LOCUS NP_391368 245 aa linear BCT 03-DEC-2008
DEFINITION 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]
imidazole-4-carboxamide isomerase [Bacillus subtilis subsp.
subtilis str. 168].
ACCESSION NP_391368
VERSION NP_391368.1 GI:16080541
DBSOURCE REFSEQ: accession NC_000964.2
KEYWORDS complete genome.
SOURCE Bacillus subtilis subsp. subtilis str. 168
ORGANISM Bacillus subtilis subsp. subtilis str. 168
Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
REFERENCE 1 (residues 1 to 245)
AUTHORS Kunst,F., Ogasawara,N., Moszer,I., Albertini,A.M., Alloni,G.,
Azevedo,V., Bertero,M.G., Bessieres,P., Bolotin,A., Borchert,S.,
Borriss,R., Boursier,L., Brans,A., Braun,M., Brignell,S.C.,
Bron,S., Brouillet,S., Bruschi,C.V., Caldwell,B., Capuano,V.,
Carter,N.M., Choi,S.K., Codani,J.J., Connerton,I.F., Cummings,N.J.,
Daniel,R.A., Denizot,F., Devine,K.M., Dusterhoft,A., Ehrlich,S.D.,
Emmerson,P.T., Entian,K.D., Errington,J., Fabret,C., Ferrari,E.,
Foulger,D., Fritz,C., Fujita,M., Fujita,Y., Fuma,S., Galizzi,A.,
Galleron,N., Ghim,S.Y., Glaser,P., Goffeau,A., Golightly,E.J.,
Grandi,G., Guiseppi,G., Guy,B.J., Haga,K., Haiech,J., Harwood,C.R.,
Henaut,A., Hilbert,H., Holsappel,S., Hosono,S., Hullo,M.F.,
Itaya,M., Jones,L., Joris,B., Karamata,D., Kasahara,Y.,
Klaerr-Blanchard,M., Klein,C., Kobayashi,Y., Koetter,P.,
Koningstein,G., Krogh,S., Kumano,M., Kurita,K., Lapidus,A.,
Lardinois,S., Lauber,J., Lazarevic,V., Lee,S.M., Levine,A., Liu,H.,
Masuda,S., Mauel,C., Medigue,C., Medina,N., Mellado,R.P.,
Mizuno,M., Moestl,D., Nakai,S., Noback,M., Noone,D., O'Reilly,M.,
Ogawa,K., Ogiwara,A., Oudega,B., Park,S.H., Parro,V., Pohl,T.M.,
Portetelle,D., Porwollik,S., Prescott,A.M., Presecan,E., Pujic,P.,
Purnelle,B., Rapoport,G., Rey,M., Reynolds,S., Rieger,M.,
Rivolta,C., Rocha,E., Roche,B., Rose,M., Sadaie,Y., Sato,T.,
Scanlan,E., Schleich,S., Schroeter,R., Scoffone,F., Sekiguchi,J.,
Sekowska,A., Seror,S.J., Serror,P., Shin,B.S., Soldo,B.,
Sorokin,A., Tacconi,E., Takagi,T., Takahashi,H., Takemaru,K.,
Takeuchi,M., Tamakoshi,A., Tanaka,T., Terpstra,P., Tognoni,A.,
Tosato,V., Uchiyama,S., Vandenbol,M., Vannier,F., Vassarotti,A.,
Viari,A., Wambutt,R., Wedler,E., Wedler,H., Weitzenegger,T.,
Winters,P., Wipat,A., Yamamoto,H., Yamane,K., Yasumoto,K., Yata,K.,
Yoshida,K., Yoshikawa,H.F., Zumstein,E., Yoshikawa,H. and
Danchin,A.
TITLE The complete genome sequence of the gram-positive bacterium
Bacillus subtilis
JOURNAL Nature 390 (6657), 249-256 (1997)
PUBMED 9384377
REFERENCE 2 (residues 1 to 245)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2001) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (residues 1 to 245)
AUTHORS Kunst,F., Ogasawara,N., Yoshikawa,H. and Danchin,A.
TITLE Direct Submission
JOURNAL Submitted (18-NOV-1997) Institut Pasteur, Regulation de
l'Expression Genetique, 28 rue du Docteur Roux, Paris Cedex 15
75724, France
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CAB15493.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..245
/organism="Bacillus subtilis subsp. subtilis str. 168"
/strain="168"
/db_xref="taxon:224308"
Protein 1..245
/product="1-(5-phosphoribosyl)-5-[(5-
phosphoribosylamino)methylideneamino]
imidazole-4-carboxamide isomerase"
/EC_number="5.3.1.16"
/function="histidine biosynthesis"
/calculated_mol_wt=26398
Region 3..245
/region_name="HisA"
/note="Phosphoribosylformimino-5-aminoimidazole
carboxamide ribonucleotide (ProFAR) isomerase [Amino acid
transport and metabolism]; COG0106"
/db_xref="CDD:30455"
Region 6..240
/region_name="HisA"
/note="HisA. Phosphoribosylformimino-5-aminoimidazole
carboxamide ribonucleotide (ProFAR) isomerase catalyzes
the fourth step in histidine biosynthesis, an
isomerisation of the aminoaldose moiety of ProFAR to the
aminoketose of PRFAR (N-(5'-phospho-D-1...; cd04732"
/db_xref="CDD:73394"
Site order(11,51,132)
/site_type="other"
/note="catalytic residues"
/db_xref="CDD:73394"
CDS 1..245
/gene="hisA"
/locus_tag="BSU34880"
/coded_by="complement(NC_000964.2:3583347..3584084)"
/note="catalyzes the formation of
5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l-
(5-phosphoribosyl)imidazole-4-carboxamide from
1-(5-phosphoribosyl)-5-[(5-
phosphoribosylamino)methylideneamino]
imidazole-4-carboxamide"
/transl_table=11
/db_xref="GOA:O35006"
/db_xref="UniProtKB/Swiss-Prot:O35006"
/db_xref="GeneID:936580"
ORIGIN
1 msaftlypai dmrngkcvrl vqgdynketi ygdspydmae lfekegaewi hlvdldgake
61 gkrvndrhvi eiaqklnlkv eigggirsen dvyeylsagv ervilgssav snppfvkkml
121 kqygekiaig ldarngfvst egwletstlk atelgkelan egaevfiftd iatdgmlsgp
181 nvkstvelak etgksviasg gvssvadlea larneadgvs gaiigkalyt nqftlseale
241 rvkrk
//