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Infect Immun. 1977 May; 16(2): 712–714.
PMCID: PMC421014
Low sucrose levels promote extensive Streptococcus mutans-induced dental caries.
S M Michalek, J R McGhee, T Shiota, and D Devenyns
Abstract
One-tenth percent sucrose significantly promotes dental caries induced by Streptococcus mutans in young gnotobiotic rats. Maximum caries activity was observed in rats provided a purified diet containing 3% sucrose.
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Selected References
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  • Frostell, G; Keyes, PH; Larson, RH. Effect of various sugars and sugar substitutes on dental caries in hamsters and rats. J Nutr. 1967 Sep;93(1):65–76. [PubMed]
  • Gibbons, RJ; van Houte, J. Dental caries. Annu Rev Med. 1975;26:121–136. [PubMed]
  • GUSTAFSSON, BE; QUENSEL, CE; LANKE, LS; LUNDQVIST, C; GRAHNEN, H; BONOW, BE; KRASSE, B. The Vipeholm dental caries study; the effect of different levels of carbohydrate intake on caries activity in 436 individuals observed for five years. Acta Odontol Scand. 1954 Sep;11(3-4):232–264. [PubMed]
  • KEYES, PH. Dental caries in the molar teeth of rats. II. A method for diagnosing and scoring several types of lesions simultaneously. J Dent Res. 1958 37(6):1088–1099.Nov–Dec; [PubMed]
  • Larje, O; Larson, RH. Reduction of dental caries in rats by intermittent feeding with sucrose substitutes. Arch Oral Biol. 1970 Sep;15(9):805–816. [PubMed]
  • Michalek, SM; McGhee, JR; Navia, JM. Virulence of Streptococcus mutans: a sensitive method for evaluating cariogenicity in young gnotobiotic rats. Infect Immun. 1975 Jul;12(1):69–75. [PubMed]
  • Michalek, SM; McGhee, JR; Shiota, T; Devenyns, D. Virulence of Streptococcus mutans: cariogenicity of S. mutans in adult gnotobiotic rats. Infect Immun. 1977 Feb;15(2):466–471. [PubMed]
  • Rosen, S. Comparison of sucrose and glucose in the causation of dental caries in gnotobiotic rats. Arch Oral Biol. 1969 May;14(5):445–450. [PubMed]
  • Shaw, JH; Krumins, I; Gibbons, RJ. Comparison of sucrose, lactose, maltose and glucose in the causation of experimental oral diseases. Arch Oral Biol. 1967 Jun;12(6):755–768. [PubMed]
  • Van Houte, J; Upeslacis, VN; Jordan, HV; Skobe, Z; Green, DB. Role of sucrose in colonization of Streptococcus mutans in conventional Sprague-Dawley rats. J Dent Res. 1976 55(2):202–215.Mar–Apr; [PubMed]