16
proteins |
OUT |
KOG2729 |
ER vesicle integral membrane protein involved in establishing cell polarity, signaling and protein degradation |
20 hits
144 letters
hsa 
633 = Hs5031639 (144) =
hsa 439 = Hs18548056 (160) =
hsa 
435 = Hs22062540 (160) =
dme 
434 = 7298291 (144) =
cel 
351 = CE23961 (145) =
spo 
148 = SPAC30C2.05 (141) =
hsa 148 = Hs7661824 (139) =
spo 137 = SPAC2C4.05 (134) =
sce 
128 = YGL054c (138) =
dme 127 = 7295853 (157) =
ath 
125 = At1g12390 (126) =
ath 124 = At3g12180 (146) =
ath 120 = At1g62880 (137) =
sce 118 = YBR210w (142) =
ath 106 = At4g12090 (145) =
cel 95 = CE27298 (56) =
hsa 63 _ Hs20476750 (223) KOG3595
spo 60 _ SPBC1683.03c (519) KOG0254
sce 59 YMR200w (256)
ecu 
59 _ ECU10g1600 (203) KOG3433
BLASTP 2.2.4 [Aug-26-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Hs5031639
(144 letters)
Database: kyvama
112,920 sequences; 47,500,486 total letters
Score E
Sequences producing significant alignments: (bits) Value
Hs5031639 248 3e-66
Hs18548056 173 9e-44
Hs22062540 172 2e-43
7298291 171 3e-43
CE23961 139 1e-33
SPAC30C2.05 62 5e-10
Hs7661824 62 5e-10
SPAC2C4.05 57 9e-09
YGL054c 54 1e-07
7295853 54 1e-07
At1g12390 53 2e-07
At3g12180 52 3e-07
At1g62880 51 8e-07
YBR210w 50 1e-06
At4g12090 45 4e-05
CE27298 41 7e-04
Hs20476750 29 3.4
SPBC1683.03c 28 7.6
YMR200w 27 9.9
ECU10g1600 27 9.9
# >Hs5031639
# Length = 144
#
# Score = 248 bits (633), Expect = 3e-66
# Identities = 117/144 (81%), Positives = 117/144 (81%)
#
# Query: 1 MAFTFAAFCYMXXXXXXXXXXXXXXWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHA 60
# MAFTFAAFCYM WHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHA
# Sbjct: 1 MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHA 60
#
# Query: 61 FFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGW 120
# FFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGW
# Sbjct: 61 FFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGW 120
#
# Query: 121 CKXXXXXXXXXXXXXGMIYVLVSS 144
# CK GMIYVLVSS
# Sbjct: 121 CKLAFYLLAFFYYLYGMIYVLVSS 144
#
#
# >Hs18548056
# Length = 160
#
# Score = 173 bits (439), Expect = 9e-44
# Identities = 86/160 (53%), Positives = 94/160 (58%), Gaps = 16/160 (10%)
#
# Query: 1 MAFTFAAFCYMXXXXXXXXXXXXXXWHIIAFDELKTDYKNPIDQCNT------------- 47
# MAFTFAAFCYM WHIIAFDEL+TD+K+PIDQCN
# Sbjct: 1 MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERI 60
#
# Query: 48 ---LNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPT 104
# L LVLPEY IH+ FC+MFLCA EWLTLGLN+PLL YH WRY P S YDP
# Sbjct: 61 CFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPP 120
#
# Query: 105 TIMNADILAYCQKEGWCKXXXXXXXXXXXXXGMIYVLVSS 144
# +MNAD L+YCQKE WCK MIY LVSS
# Sbjct: 121 VVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 160
#
#
# >Hs22062540
# Length = 160
#
# Score = 172 bits (435), Expect = 2e-43
# Identities = 84/159 (52%), Positives = 94/159 (58%), Gaps = 16/159 (10%)
#
# Query: 1 MAFTFAAFCYMXXXXXXXXXXXXXXWHIIAFDELKTDYKNPIDQ---------------- 44
# MAFTFAAFCYM WHIIAFDEL+TD+KNPIDQ
# Sbjct: 1 MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERI 60
#
# Query: 45 CNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPT 104
# C L LV+PEY IH FC+MFLCAAEW+TLGLN+PLL YH+WRY RP +YD
# Sbjct: 61 CCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAV 120
#
# Query: 105 TIMNADILAYCQKEGWCKXXXXXXXXXXXXXGMIYVLVS 143
# +IMNADIL YCQKE WCK M+Y LVS
# Sbjct: 121 SIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVS 159
#
#
# >7298291
# Length = 144
#
# Score = 171 bits (434), Expect = 3e-43
# Identities = 78/144 (54%), Positives = 96/144 (66%)
#
# Query: 1 MAFTFAAFCYMXXXXXXXXXXXXXXWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHA 60
# MAF F AF Y+ +H+IAFDELKTDYKNPIDQCN+LNPLVLPEYL+H
# Sbjct: 1 MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQCNSLNPLVLPEYLLHI 60
#
# Query: 61 FFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGW 120
# F ++FL EW +L +N+PL+AYHIWRY +RPVMSGPGLYDPTT++ D L +EGW
# Sbjct: 61 FLNLLFLFCGEWFSLCINIPLIAYHIWRYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGW 120
#
# Query: 121 CKXXXXXXXXXXXXXGMIYVLVSS 144
# K GM+Y L+S+
# Sbjct: 121 IKLAVYLISFFYYIYGMVYSLIST 144
#
#
# >CE23961
# Length = 145
#
# Score = 139 bits (351), Expect = 1e-33
# Identities = 66/144 (45%), Positives = 87/144 (59%)
#
# Query: 1 MAFTFAAFCYMXXXXXXXXXXXXXXWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHA 60
# MAFTFAAFCY+ + +I DEL+TDYKNPI+QC LN L+LPEY+IH
# Sbjct: 1 MAFTFAAFCYLLALIAVGFCIFFAIYTVICVDELRTDYKNPIEQCRNLNQLILPEYIIHG 60
#
# Query: 61 FFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGW 120
# F V+F+ + + +++ N+PL YHI+ Y RPVMSGPG+YDPTTI+N L+ + W
# Sbjct: 61 TFTVLFIFSWQLISILANLPLAFYHIYTYAKRPVMSGPGIYDPTTILNRSTLSSTLRISW 120
#
# Query: 121 CKXXXXXXXXXXXXXGMIYVLVSS 144
# K MIY LV+S
# Sbjct: 121 IKLAFYLVSFFYYLYAMIYTLVTS 144
#
#
# >SPAC30C2.05
# Length = 141
#
# Score = 61.6 bits (148), Expect = 5e-10
# Identities = 26/58 (44%), Positives = 36/58 (61%)
#
# Query: 28 IIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# +I F +L+ DY NPID CN LN LV+PE + H ++ L +WL N+PLL +H
# Sbjct: 31 VIMFSDLEMDYINPIDLCNKLNDLVMPEIISHTLVTLLLLLGKKWLLFLANLPLLVFH 88
#
#
# >Hs7661824
# Length = 139
#
# Score = 61.6 bits (148), Expect = 5e-10
# Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
#
# Query: 26 WHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# + II +L+ DY N C+ LN V+PE + H V+ L + W LN+P+ ++
# Sbjct: 22 YFIITLSDLECDYINARSCCSKLNKWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWN 81
#
# Query: 86 IWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKXXXXXXXXXXXXXGMIYVLVS 143
# I+RY+ P G++DPT I N L KE K MI L++
# Sbjct: 82 IYRYIMVP-SGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYSMILALIN 138
#
#
# >SPAC2C4.05
# Length = 134
#
# Score = 57.4 bits (137), Expect = 9e-09
# Identities = 31/101 (30%), Positives = 51/101 (49%), Gaps = 5/101 (4%)
#
# Query: 6 AAFCYMXXXXXXXXXXXXXXWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVM 65
# +A+ Y + + + +LK D+ NPID LN VLPE AF ++
# Sbjct: 3 SAWIYFTSLMLTCANIMLQMYFTVMYSDLKDDFINPIDLSRKLNWYVLPEMGFQAFSALL 62
#
# Query: 66 FLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTI 106
# L + W+T LN+P+LA++ ++ +MS ++D TTI
# Sbjct: 63 LLLSGAWITFLLNVPMLAWN-----AKMIMSNTHMHDSTTI 98
#
#
# >YGL054c
# Length = 138
#
# Score = 53.9 bits (128), Expect = 1e-07
# Identities = 22/58 (37%), Positives = 36/58 (61%)
#
# Query: 29 IAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHI 86
# I + +L+ DY NPI+ C+ +N L+ PE +H ++FL W LN+P+LAY++
# Sbjct: 25 ILYADLEADYINPIELCSKVNKLITPEAALHGALSLLFLLNGYWFVFLLNLPVLAYNL 82
#
#
# >7295853
# Length = 157
#
# Score = 53.5 bits (127), Expect = 1e-07
# Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
#
# Query: 26 WHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# ++++ +L+ DY N + C LN V+P++ HA CV+ L W+ LN+P++
# Sbjct: 25 YYVLTLADLECDYLNAQECCRRLNFWVIPKFGSHALLCVLLLLGGHWVMFLLNLPMV--- 81
#
# Query: 86 IWRY--MSRPVMSGPGLYDPTTIMNADIL 112
# IW + + R G+YDP I + +L
# Sbjct: 82 IWLFYELHRQRRDSLGVYDPVDIHSRGLL 110
#
#
# >At1g12390
# Length = 126
#
# Score = 52.8 bits (125), Expect = 2e-07
# Identities = 26/83 (31%), Positives = 40/83 (47%), Gaps = 5/83 (6%)
#
# Query: 26 WHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# + ++ +L+ DY NP D + +N +VLPE+++ CV +L W L +P L Y+
# Sbjct: 23 YQLVCLADLEFDYINPYDSASRINSVVLPEFIVQGVLCVFYLLTGHWFMTLLCLPYLYYN 82
#
# Query: 86 IWRYMSRPVMSGPGLYDPTTIMN 108
# Y R L D T I N
# Sbjct: 83 FHLYSKR-----QHLVDVTEIFN 100
#
#
# >At3g12180
# Length = 146
#
# Score = 52.4 bits (124), Expect = 3e-07
# Identities = 20/67 (29%), Positives = 36/67 (52%)
#
# Query: 26 WHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# + +I +L+ DY NP + +N LV+PE+++ C++FL W+ + +P+ YH
# Sbjct: 24 YQVICLTDLEADYLNPFETSTRINRLVIPEFILQGSLCLLFLLTWHWVFFLVAVPVTVYH 83
#
# Query: 86 IWRYMSR 92
# Y R
# Sbjct: 84 AMLYKER 90
#
#
# >At1g62880
# Length = 137
#
# Score = 50.8 bits (120), Expect = 8e-07
# Identities = 27/83 (32%), Positives = 41/83 (48%), Gaps = 5/83 (6%)
#
# Query: 26 WHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# + +I+ +L+ DY NP D + +N +VLPE ++ F CV +L W L +P L Y+
# Sbjct: 23 YQLISLADLEFDYINPYDSASRINFVVLPESILQGFLCVFYLVTGHWFMALLCVPYLYYN 82
#
# Query: 86 IWRYMSRPVMSGPGLYDPTTIMN 108
# Y + L D T I N
# Sbjct: 83 FHLYSRK-----QHLIDVTEIFN 100
#
#
# >YBR210w
# Length = 142
#
# Score = 50.1 bits (118), Expect = 1e-06
# Identities = 22/57 (38%), Positives = 34/57 (59%)
#
# Query: 29 IAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYH 85
# I + +L+ DY N I+ C +N L +PE ++ AF +FL W LN+P+LAY+
# Sbjct: 28 ILYGDLEADYINSIELCKRVNRLSVPEAILQAFISALFLFNGYWFVFLLNVPVLAYN 84
#
#
# >At4g12090
# Length = 145
#
# Score = 45.4 bits (106), Expect = 4e-05
# Identities = 20/60 (33%), Positives = 33/60 (54%)
#
# Query: 33 ELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSR 92
# +L+ D NP D + +N +VLPE+ + C+ ++ W L++P L Y+I YM R
# Sbjct: 40 DLEFDRINPYDVSSRINRMVLPEFGLQGLLCLYYILTGHWFMAVLSLPHLFYNIRLYMKR 99
#
#
# >CE27298
# Length = 56
#
# Score = 41.2 bits (95), Expect = 7e-04
# Identities = 20/51 (39%), Positives = 26/51 (50%)
#
# Query: 94 VMSGPGLYDPTTIMNADILAYCQKEGWCKXXXXXXXXXXXXXGMIYVLVSS 144
# +M GPG+YDPTTI+N L+ + W K MIY LV+S
# Sbjct: 1 MMPGPGIYDPTTILNRSTLSSTLRISWIKLAFYLVSFFYYLYVMIYTLVTS 51
#
#
# >Hs20476750
# Length = 223
#
# Score = 28.9 bits (63), Expect = 3.4
# Identities = 15/38 (39%), Positives = 21/38 (54%), Gaps = 1/38 (2%)
#
# Query: 84 YHIWRYMSRP-VMSGPGLYDPTTIMNADILAYCQKEGW 120
# Y +W S P VM GL+ P + + A + A C+K GW
# Sbjct: 63 YMLWVTESEPSVMWLSGLHIPESYLTALVQATCRKNGW 100
#
#
# >SPBC1683.03c
# Length = 519
#
# Score = 27.7 bits (60), Expect = 7.6
# Identities = 11/43 (25%), Positives = 22/43 (50%), Gaps = 4/43 (9%)
#
# Query: 48 LNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYM 90
# + P++ P + CV+ AA W G+ M Y++W+++
# Sbjct: 294 VQPILAPSMMNSEMGCVLICVAAGWACFGIWM----YYLWQFL 332
#
#
# >YMR200w
# Length = 256
#
# Score = 27.3 bits (59), Expect = 9.9
# Identities = 19/57 (33%), Positives = 23/57 (40%), Gaps = 12/57 (21%)
#
# Query: 47 TLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDP 103
# TL L+L YL F C E ++ Y W S V +GPG YDP
# Sbjct: 7 TLKKLILGGYL----FAQKVYCEDESNSI--------YGTWSSKSNQVFTGPGFYDP 51
#
#
# >ECU10g1600
# Length = 203
#
# Score = 27.3 bits (59), Expect = 9.9
# Identities = 12/35 (34%), Positives = 20/35 (56%), Gaps = 2/35 (5%)
#
# Query: 29 IAFDELKTDYKNPIDQCNTL--NPLVLPEYLIHAF 61
# IA+D+L D K D+CN + N ++ +Y+ F
# Sbjct: 148 IAYDKLVADRKEMADECNRIIDNVFIIQDYICSKF 182
#
#
Database: kyvama
Posted date: Nov 8, 2002 2:42 AM
Number of letters in database: 47,500,486
Number of sequences in database: 112,920
Lambda K H
0.331 0.143 0.499
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,494,907
Number of Sequences: 112920
Number of extensions: 418482
Number of successful extensions: 866
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 848
Number of HSP's gapped (non-prelim): 20
length of query: 144
length of database: 47,500,486
effective HSP length: 98
effective length of query: 46
effective length of database: 36,434,326
effective search space: 1675978996
effective search space used: 1675978996
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 59 (27.3 bits)
S2: 59 (27.3 bits)