PUMA2 -- Evolutionary Analysis of Metabolism

PUMA2 is not being maintained or updated by Argonne National Laboratory and will be taken down in the near future. If there is any data here that you wish to preserve, you are responsible for downloading it. An overview of the bioinformatics research being conducted at the Mathematics and Computer Science Division is available at this page.

EC-number:  4.2.1.20 ----- tryptophan synthase

EC-NUMBER	4.2.1.20
ENZYME-NAME	tryptophan synthase
ENZYME-SYSNAME	A pyridoxal-phosphate protein. The alpha-subunit catalyses the conversion of 1-C-(indol-3-yl)glycerol 3-phosphate to indole and glyceraldehyde 3-phosphate. The indole then migrates to the beta-subunit where, with serine in the presence of pyridoxal 5''-phosphate, it is converted to tryptophan. Also catalyses the conversion of serine and indole into tryptophan and water, and of indoleglycerol phosphate into indole and glyceraldehyde phosphate (the latter reaction was listed formerly as EC 4.1.2.8). In some organisms, this enzyme is part of a multifunctional protein, together with one or more other components of the system for the biosynthesis of tryptophan [EC 2.4.2.18 (anthranilate phosphoribosyltransferase), EC 4.1.1.48 (indole-3-glycerol-phosphate synthase), EC 4.1.3.27 (anthranilate synthase) and EC 5.3.1.24 (phosphoribosylanthranilate isomerase)].
ENZYME-CLASS	Lyases Carbon-oxygen lyases Hydro-lyases
SYNONYMS	L-tryptophan synthetase;; indoleglycerol phosphate aldolase;; tryptophan desmolase;; tryptophan synthase;;   >>more synonyms
REACTION	L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate [RN:R02722]
PATHWAY	EMP-PATHWAYS: Chorismate,_Glutamine--Tryptophan,_Glyceraldehyde_3-phosphate_Anabolism;   >>more EMP pathways
	KEGG-PATHWAYS: Phenylalanine, tyrosine and tryptophan biosynthesis; Two-component system - General;   >>more KEGG pathways
GO_TERM	GO:0004834:tryptophan synthase activity
ENZYME-COMMENT	L-serine hydro-lyase (adding indoleglycerol-phosphate)

ExternalDB ----- DBLINKS Diseases Structure Gene Motif Ortholog Literature Other

InterPro Domains found in sequences annotated as EC 4.2.1.20    IPR000010 Proteinase inhibitor I25, cystatin    IPR000169 Peptidase, cysteine peptidase active site    IPR000652 Triosephosphate isomerase    IPR000794 Beta-ketoacyl synthase    IPR000834 Peptidase M14, carboxypeptidase A    IPR000909 Phosphatidylinositol-specific phospholipase C, X region    IPR001226 Flavodoxin    IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit    IPR002028 Tryptophan synthase, alpha chain    IPR002086 Aldehyde dehydrogenase    IPR002110 Ankyrin    IPR002345 Lipocalin    IPR003009 FMN/related compound-binding core    IPR003975 Shal voltage-gated K+ channel    IPR005137 Photosystem I assembly BtpA    IPR005828 General substrate transporter    IPR006316 Tryptophan synthase, beta chain-like    IPR006653 Tryptophan synthase, beta chain and related    IPR006654 Tryptophan synthase, beta chain    IPR008205 PcrB-like protein    IPR011060 Ribulose-phosphate binding barrel   color IDs with selected Interpro hits color IDs with selected Interpro hits (AND NO OTHERS)       PIR SuperFamilies containing EC 4.2.1.20 SF001411 tryptophan synthase alpha chain SF001412 yeast tryptophan synthase SF001413 tryptophan synthase, beta subunit Taxonomic breakdown of EC 4.2.1.20 sequences To perform phylogenetic analysis, first select some protein ids by clicking on their checkboxes, then click on one of the buttons below.   Additional gi numbers:    Archaea Crenarchaeota Thermoprotei Aeropyrum pernix 14601988 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002110 Ankyrin IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 14602139 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 14602140 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR008205 PcrB-like protein IPR011060 Ribulose-phosphate binding barrel Pyrobaculum aerophilum 18160891 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Sulfolobus acidocaldarius 70607174 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 70607175 IPR000652 Triosephosphate isomerase IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Sulfolobus solfataricus 13814067 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 13814068 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 13814334 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Sulfolobus tokodaii 15622281 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15622282 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Euryarchaeota Archaeoglobi Archaeoglobus fulgidus 11498839 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 11499192 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 11499193 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Halobacteria Haloarcula marismortui 55231344 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 55231345 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Halobacterium salinarum 15789583 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 16554463 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Haloferax volcanii 136258 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 136274 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Natronomonas pharaonis 76802221 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 76802222 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 76802389 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Methanobacteria Methanothermobacter thermautotrophicus 149749 2622591 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 2622787 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Methanococci Methanocaldococcus jannaschii 15669226 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15669227 Methanococcus maripaludis 45358565 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 45358566 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Methanococcus voltae 150072 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 150073 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Methanomicrobia Methanosarcina acetivorans 19916995 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 19916996 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 19917223 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Methanosarcina mazei 21226439 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 21228923 IPR000652 Triosephosphate isomerase IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Methanopyri Methanopyrus kandleri 20093841 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 20094221 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Thermococci Pyrococcus abyssi 14520674 IPR000652 Triosephosphate isomerase IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 14520675 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 14520795 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Pyrococcus furiosus 18977964 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 22775324 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 22775325 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Pyrococcus horikoshii 14591361 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Thermococcus kodakarensis 57640192 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 57640193 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 57641377 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Thermoplasmata Picrophilus torridus 48429861 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 48430065 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 48430066 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Thermoplasma acidophilum 10639955 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Thermoplasma volcanium 13541762 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Bacteria Actinobacteria Actinobacteria (class) Bifidobacterium longum 23465333 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Corynebacterium diphtheriae 38201150 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 38201158 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 38201159 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Corynebacterium efficiens 23494716 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 23494717 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Corynebacterium glutamicum 39597 39598 12541874 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 19554225 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Corynebacterium jeikeium 68263472 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 68263473 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Leifsonia xyli 50954795 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 50954796 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Mycobacterium avium 41407405 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Mycobacterium bovis 31792799 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Mycobacterium intracellulare 6226270 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 6226275 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Mycobacterium leprae 4883463 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 13093205 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 13093206 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Mycobacterium tuberculosis 13881278 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 31792798 31792799 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Nocardia farcinica 54023830 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Propionibacterium acnes 50842610 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 50842611 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Streptomyces avermitilis 29832719 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 29832720 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Streptomyces coelicolor 21220517 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 21220518 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Symbiobacterium thermophilum 51892553 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Thermobifida fusca 72161570 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Aquificae Aquificae (class) Aquifex aeolicus 15606106 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15606594 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 15606687 IPR000909 Phosphatidylinositol-specific phospholipase C, X region IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bacteroidetes Bacteroidetes (class) Bacteroides fragilis 60492151 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 60493581 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 60493587 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Bacteroides thetaiotaomicron 29337831 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 29337837 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Chlamydiae Chlamydiae (class) Chlamydia trachomatis 6599049 IPR000834 Peptidase M14, carboxypeptidase A IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 20805962 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 20805963 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 76788890 76788891 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006654 Tryptophan synthase, beta chain Chlamydophila caviae 29840318 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 29840324 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 29840325 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Chlorobi Chlorobia Chlorobaculum tepidum 21673033 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related 21673356 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 21673370 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Chlorobium chlorochromatii 78188429 78189262 78189280 Pelodictyon luteolum 78186429 78187771 Chloroflexi Dehalococcoidetes Dehalococcoides ethenogenes 57233819 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 57233820 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Dehalococcoides sp. CBDB1 73660870 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 73660871 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Cyanobacteria Anabaena variabilis 75908132 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 75908303 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Nostoc sp. PCC 7120 17129755 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 17132928 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Prochlorococcus marinus 33239640 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 33240025 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 33634654 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 33641072 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 33860724 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 33861129 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 72381848 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 78778957 Synechococcus elongatus 56751115 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Synechococcus sp. CC9605 78212524 78213926 Synechococcus sp. CC9902 78184471 Synechococcus sp. PCC 7002 22652014 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Synechococcus sp. WH 8102 33639028 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 33639411 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Synechocystis sp. PCC 6803 16329464 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 16332038 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Gloeobacteria Gloeobacter violaceus 35213181 IPR000834 Peptidase M14, carboxypeptidase A IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 35213327 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Deinococcus-Thermus Deinococci Deinococcus radiodurans 15805965 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15805966 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Thermus thermophilus 155133 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 46199037 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 55981063 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Firmicutes Bacilli Bacillus anthracis 65318615 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 65318616 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bacillus cereus 30019390 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 30019391 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 42736354 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 42736355 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 51977561 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 51977562 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Bacillus clausii 56963664 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 56963665 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bacillus halodurans 10174280 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 10174281 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bacillus licheniformis 52003982 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bacillus subtilis 143773 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 143812 18390356 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR005828 General substrate transporter IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 22775329 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 50812257 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Bacillus thuringiensis 49477158 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 65318615 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Geobacillus kaustophilus 56420637 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 56420734 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 56420735 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Geobacillus stearothermophilus 136253 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 136269 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Lactobacillus casei 136260 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 136276 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Lactobacillus plantarum 28378349 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 28378350 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Lactococcus lactis 149521 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 149522 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Listeria innocua 16414155 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 16414156 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Listeria monocytogenes 16411063 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 16411064 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 46907857 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 46907858 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Oceanobacillus iheyensis 23097976 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR005137 Photosystem I assembly BtpA IPR011060 Ribulose-phosphate binding barrel 23097977 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Staphylococcus aureus 46580 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15924362 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15924363 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 21204427 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 49244658 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 49244659 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 49483565 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 49483566 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Staphylococcus epidermidis 27467971 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 27467972 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Streptococcus mutans 24379019 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 24379020 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Streptococcus pneumoniae 15459301 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15459302 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15901640 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15901641 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Streptococcus thermophilus 55739476 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 55821563 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Clostridia Carboxydothermus hydrogenoformans 78044192 78044818 Clostridium acetobutylicum 15026224 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15026225 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Heliobacillus mobilis 27262488 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Thermoanaerobacter tengcongensis 20808006 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 20808007 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Fusobacteria Fusobacteria (class) Fusobacterium nucleatum 19713780 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Planctomycetes Planctomycetacia Rhodopirellula baltica 32447086 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Proteobacteria Alphaproteobacteria Agrobacterium tumefaciens 17933943 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Azospirillum brasilense 7381257 IPR000169 Peptidase, cysteine peptidase active site IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bradyrhizobium japonicum 27375856 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 27375857 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Brucella melitensis 17984073 17984074 23348992 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 23348994 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 62290950 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Candidatus Pelagibacter ubique 71062306 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 71062307 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Caulobacter vibrioides 136272 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 144288 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Gluconobacter oxydans 58039654 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 58039655 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Mesorhizobium loti 13474230 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR003975 Shal voltage-gated K+ channel IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 13474231 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Nitrobacter winogradskyi 75674253 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 75674254 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Rhizobium etli 5834681 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 45505288 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 45505289 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Rhodobacter sphaeroides 4761127 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 4761131 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 77462053 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Rhodopseudomonas palustris 39933149 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 39933150 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 39934666 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Silicibacter pomeroyi 56677447 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 56677454 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Sinorhizobium meliloti 15072956 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15072957 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Zymomonas mobilis 56543055 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 73622061 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Betaproteobacteria Azoarcus sp. EbN1 56478136 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Bordetella bronchiseptica 33597847 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 33602748 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Bordetella parapertussis 33574275 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 33574276 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Bordetella pertussis 33594458 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 33594459 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Burkholderia mallei 53716176 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 67637617 IPR000010 Proteinase inhibitor I25, cystatin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Burkholderia pseudomallei 53722719 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 67755675 IPR000010 Proteinase inhibitor I25, cystatin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 76818222 IPR000010 Proteinase inhibitor I25, cystatin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 76819683 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Burkholderia sp. 383 78062970 78062972 Chromobacterium violaceum 34498216 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Cupriavidus necator 73541990 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Neisseria gonorrhoeae 25052797 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002086 Aldehyde dehydrogenase IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 59800701 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 59800724 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Neisseria meningitidis 7379594 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 7379616 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15676576 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15676597 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Nitrosomonas europaea 30248702 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 30248703 IPR000909 Phosphatidylinositol-specific phospholipase C, X region IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Ralstonia solanacearum 17428999 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 17429001 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Thiobacillus denitrificans 74317931 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 74317932 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Deltaproteobacteria Desulfotalea psychrophila 50876519 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Desulfovibrio desulfuricans 78358517 Desulfovibrio vulgaris 46578502 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 46578886 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 46578887 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Geobacter sulfurreducens 39984358 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Epsilonproteobacteria Campylobacter jejuni 57237403 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 57237404 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Helicobacter hepaticus 32262965 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel 32262966 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Helicobacter pylori 15612263 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15612264 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15645891 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15645892 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Thiomicrospira denitrificans 78777878 Wolinella succinogenes 34482842 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002110 Ankyrin IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 34483424 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 34483845 IPR002028 Tryptophan synthase, alpha chain IPR011060 Ribulose-phosphate binding barrel Gammaproteobacteria Acinetobacter calcoaceticus 141798 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Acinetobacter sp. ADP1 50083869 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 50083874 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Buchnera aphidicola 396658 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 396659 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 769838 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 769839 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 1081994 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related 1081998 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related 3170097 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 3170098 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 6492283 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 6492284 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15616888 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 15616889 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 27904150 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 27904151 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Candidatus Blochmannia floridanus 33519884 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 33519885 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Colwellia psychrerythraea 71277952 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 71278320 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 71278975 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Coxiella burnetii 29654461 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Escherichia coli 43184 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 775160 775167 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 775188 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 1742050 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15801917 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 15801918 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Francisella tularensis 56708766 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 56708767 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Haemophilus influenzae 16273336 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 16273337 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 68058238 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 68058239 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Idiomarina loihiensis 56460857 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Klebsiella aerogenes 43783 IPR006653 Tryptophan synthase, beta chain and related 43784 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Legionella pneumophila 52841535 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 52841536 IPR001226 Flavodoxin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 54294203 IPR001226 Flavodoxin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 54297224 IPR001226 Flavodoxin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Mannheimia succiniciproducens 52307261 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Methylococcus capsulatus 53803318 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 53803319 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Nitrosococcus oceani 77164533 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 77164534 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Pasteurella multocida 733126 12720845 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 12720846 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pectobacterium atrosepticum 49611754 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 49611755 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Photobacterium profundum 54309655 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Photorhabdus luminescens 37526359 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 37526360 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Pseudoalteromonas haloplanktis 77360231 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 77360232 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pseudomonas aeruginosa 9945856 IPR001226 Flavodoxin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 9945857 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pseudomonas fluorescens 70733549 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 70733550 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pseudomonas putida 45749 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 45750 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 26986827 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 26986828 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pseudomonas savastanoi 28883193 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 71733716 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 71734425 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pseudomonas syringae 151619 IPR001226 Flavodoxin IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 151620 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 63254011 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 63254012 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Pseudomonas syringae group genomosp. 3 28867398 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 28867399 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Psychrobacter arcticus 71065002 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 71065003 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Salmonella paratyphi 56413348 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Salmonella typhimurium 47940 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 47942 6851080 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 29142074 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Shewanella oneidensis 24374548 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 24374549 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Shigella flexneri 16129221 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 16129222 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Thiomicrospira crunogena 78485149 78486328 Vibrio cholerae 75829478 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 75829479 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Vibrio fischeri 59711634 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 59711635 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Vibrio metschnikovii 6689542 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 6689543 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Vibrio parahaemolyticus 28898734 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 28898735 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 28900440 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Vibrio vulnificus 27366338 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 37679400 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 37679401 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Xanthomonas axonopodis 21243443 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 21243444 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Xanthomonas campestris 66767899 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 66767901 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 78048421 78048425 Xylella fastidiosa 15837977 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 28198521 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 28198522 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 77747544 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Yersinia pestis 45436663 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 51596452 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Yersinia pseudotuberculosis 51596451 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 51596452 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Spirochaetes Spirochaetes (class) Leptospira biflexa 56384920 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR005137 Photosystem I assembly BtpA IPR011060 Ribulose-phosphate binding barrel Leptospira interrogans 45656750 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 45656751 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Thermotogae Thermotogae (class) Thermotoga maritima 1054861 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 4980629 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 4981053 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006316 Tryptophan synthase, beta chain-like IPR006653 Tryptophan synthase, beta chain and related Eukaryota Bangiophyceae Cyanidioschyzon merolae 30409152 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Cyanidium caldarium 3915890 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 6466362 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Porphyra purpurea 1717756 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Florideophyceae Antithamnion sp. 11331 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Gracilaria tenuistipitata 51210034 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Ascomycota Eurotiomycetes Emericella nidulans 9651535 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002028 Tryptophan synthase, alpha chain IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain IPR011060 Ribulose-phosphate binding barrel Saccharomycetes Saccharomyces cerevisiae 6321412 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain IPR011060 Ribulose-phosphate binding barrel Schizosaccharomycetes Schizosaccharomyces pombe 2388914 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002028 Tryptophan synthase, alpha chain IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain IPR011060 Ribulose-phosphate binding barrel 7436997 Sordariomycetes Neurospora crassa 136372 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002028 Tryptophan synthase, alpha chain IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain IPR011060 Ribulose-phosphate binding barrel Basidiomycota Homobasidiomycetes Coprinopsis cinerea 32307635 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain IPR011060 Ribulose-phosphate binding barrel Chlorophyta Chlorophyceae Chlamydomonas reinhardtii 2970343 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Streptophyta Arabidopsis thaliana 3892048 IPR000652 Triosephosphate isomerase IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 7258367 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel 7269560 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 22137210 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Camptotheca acuminata 2801771 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain Isatis tinctoria 52673242 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel Liliopsida Oryza sativa 2081609 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006654 Tryptophan synthase, beta chain Zea mays 440171 1174778 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 1174780 IPR001926 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit IPR006653 Tryptophan synthase, beta chain and related IPR006654 Tryptophan synthase, beta chain 30720306 IPR002028 Tryptophan synthase, alpha chain IPR003009 FMN/related compound-binding core IPR011060 Ribulose-phosphate binding barrel   Additional gi numbers:    To perform phylogenetic analysis: Select some ids by clicking on their checkboxes. Click on one of the buttons above.

Front page | Protein Query | Acknowledgements | Site Map Disclaimer | Security Notice Questions & Concerns: puma2@mcs.anl.gov