R = Retrieve links to Related sequences (neighbors).
Use the 
icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
Use the 
icon (if present) to retrieve links to the Ligand Enzyme and Chemical Compound Database .
Use the 
icon (if present) to retrieve links to the Protein Data Bank database.
WARNING: Descriptions of 1285 database sequences were not reported due to the
limiting value of parameter V = 50.
>gi|7433539|pir||B71400 glycine hydroxymethyltransferase (EC 2.1.2.1) -
Arabidopsis thaliana >gi|2244749|emb|CAB10172.1| (Z97335)
hydroxymethyltransferase [Arabidopsis thaliana]
>gi|7268097|emb|CAB78435.1| (AL161537) hydroxymethyltransferase
[Arabidopsis thaliana]
Length = 471
Frame 3 hits (HSPs): ______________________
Frame 1 hits (HSPs): __________
__________________________________________________
Database sequence: | | | | | 471
0 150 300 450
Plus Strand HSPs:
Score = 658 (231.6 bits), Expect = 1.4e-63, P = 1.4e-63
Identities = 133/194 (68%), Positives = 146/194 (75%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D +WGVNVQPYSGSPANFAAYTA+L PHDRIMGLDLPSGGHLTHGYYTSGG ISATSI
Sbjct: 93 DPAAWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHLTHGYYTSGGKKISATSI 152
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF SLPYKVN TTGYIDYD+LEEKAL FRPKL+ICGGSAYPRDWDY RFR IADK GALL
Sbjct: 153 YFESLPYKVNFTTGYIDYDKLEEKALDFRPKLLICGGSAYPRDWDYARFRAIADKVGALL 212
Query: 369 LLRXGAHXRPCWPPKN*T-PFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNPQKRA-PEXR 539
L AH + PF YC +VTTTTHK+ G F +GP P K+ PE
Sbjct: 213 LCDM-AHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIFYRKGPKPPKKGQPEGA 271
Query: 540 -FLFQEKLTLGVPFPA 584
+ F++K+ V FPA
Sbjct: 272 VYDFEDKINFAV-FPA 286
Score = 92 (32.4 bits), Expect = 1.2, P = 0.69
Identities = 31/89 (34%), Positives = 38/89 (42%), Frame = +1
Query: 358 GHCFSCXMAHTXGLVGRPRIEHPSXIAXL*PPPPIK-LAGSTGXDXXLPKGPTP-KKGRX 531
G C MAH GLV +P + K L G KGP P KKG+
Sbjct: 209 GALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIFYRKGPKPPKKGQP 268
Query: 532 KXVFY-FKKN*LWG-FPSLQGGPQ-HQFG 609
+ Y F+ + FP+LQGGP HQ G
Sbjct: 269 EGAVYDFEDKINFAVFPALQGGPHNHQIG 297
>gi|11762130|gb|AAG40343.1|AF324991_1 (AF324991) DL3005C [Arabidopsis thaliana]
Length = 471
Frame 3 hits (HSPs): ______________________
Frame 1 hits (HSPs): __________
__________________________________________________
Database sequence: | | | | | 471
0 150 300 450
Plus Strand HSPs:
Score = 658 (231.6 bits), Expect = 1.4e-63, P = 1.4e-63
Identities = 133/194 (68%), Positives = 146/194 (75%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D +WGVNVQPYSGSPANFAAYTA+L PHDRIMGLDLPSGGHLTHGYYTSGG ISATSI
Sbjct: 93 DPAAWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHLTHGYYTSGGKKISATSI 152
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF SLPYKVN TTGYIDYD+LEEKAL FRPKL+ICGGSAYPRDWDY RFR IADK GALL
Sbjct: 153 YFESLPYKVNFTTGYIDYDKLEEKALDFRPKLLICGGSAYPRDWDYARFRAIADKVGALL 212
Query: 369 LLRXGAHXRPCWPPKN*T-PFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNPQKRA-PEXR 539
L AH + PF YC +VTTTTHK+ G F +GP P K+ PE
Sbjct: 213 LCDM-AHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIFYRKGPKPPKKGQPEGA 271
Query: 540 -FLFQEKLTLGVPFPA 584
+ F++K+ V FPA
Sbjct: 272 VYDFEDKINFAV-FPA 286
Score = 92 (32.4 bits), Expect = 1.2, P = 0.69
Identities = 31/89 (34%), Positives = 38/89 (42%), Frame = +1
Query: 358 GHCFSCXMAHTXGLVGRPRIEHPSXIAXL*PPPPIK-LAGSTGXDXXLPKGPTP-KKGRX 531
G C MAH GLV +P + K L G KGP P KKG+
Sbjct: 209 GALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIFYRKGPKPPKKGQP 268
Query: 532 KXVFY-FKKN*LWG-FPSLQGGPQ-HQFG 609
+ Y F+ + FP+LQGGP HQ G
Sbjct: 269 EGAVYDFEDKINFAVFPALQGGPHNHQIG 297
>gi|7433549|pir||T05258 glycine hydroxymethyltransferase (EC 2.1.2.1) F18A5.280
- Arabidopsis thaliana >gi|4455318|emb|CAB36853.1| (AL035528)
glycine hydroxymethyltransferase-like protein [Arabidopsis
thaliana] >gi|7268093|emb|CAB78431.1| (AL161537) glycine
hydroxymethyltransferase-like protein [Arabidopsis thaliana]
Length = 470
Frame 3 hits (HSPs): _____________________
__________________________________________________
Database sequence: | | | | | 470
0 150 300 450
Plus Strand HSPs:
Score = 618 (217.5 bits), Expect = 2.4e-59, P = 2.4e-59
Identities = 120/192 (62%), Positives = 141/192 (73%), Frame = +3
Query: 15 QSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYF 194
+ WGVNVQPYSGSPANFAAYTA+L PHDRIMGLDLPSGGH+THGYY+SGG ISATSIYF
Sbjct: 95 EKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYF 154
Query: 195 XSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLL 374
+LPYKV+S TGYIDYD+LEEKA+ FRPKLIICGG++YPR+WDY RFR +ADK GA LL
Sbjct: 155 ENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLC 214
Query: 375 RXGAHXRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNPQKRA-PEXR-FL 545
+ + PF YC +VTT+THK+ G F +GP P K+ PE +
Sbjct: 215 DMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYD 274
Query: 546 FQEKLTLGVPFPA 584
F K+ V FPA
Sbjct: 275 FDAKINSAV-FPA 286
>gi|9280677|gb|AAF86546.1|AC069252_5 (AC069252) F2E2.7 [Arabidopsis thaliana]
Length = 599
Frame 3 hits (HSPs): __________________
Frame 1 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | | 599
0 150 300 450
Plus Strand HSPs:
Score = 528 (185.9 bits), Expect = 4.8e-53, Sum P(2) = 4.8e-53
Identities = 102/197 (51%), Positives = 134/197 (68%), Frame = +3
Query: 15 QSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYF 194
+ WGVNVQPYS + ANFA +T +L P +RIMGLD PSGGH++HGYYT GG +S SI+F
Sbjct: 225 EKWGVNVQPYSCTSANFAVFTGLLMPGERIMGLDSPSGGHMSHGYYTPGGKKVSGASIFF 284
Query: 195 XSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLL 374
S PYKV+ TGYIDYD+LEEKAL +RPK++ICGGS+YPRDW++ RFR IADKCGA+L+
Sbjct: 285 ESFPYKVDPRTGYIDYDKLEEKALDYRPKILICGGSSYPRDWEFPRFRHIADKCGAVLMF 344
Query: 375 RXGAHXRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXFTE-GPNPQKRA-------P 530
++ PF YC IVT+TTHK+ G F + G P+K++
Sbjct: 345 DMAQISGLVAAKESPNPFDYCDIVTSTTHKSLRGPRGGIIFYKRGLKPKKQSINLNHCES 404
Query: 531 EXRFLFQEKLTLGVPFPA 584
++ F+EK+ V FP+
Sbjct: 405 NIQYDFEEKINFSV-FPS 421
Score = 48 (16.9 bits), Expect = 4.8e-53, Sum P(2) = 4.8e-53
Identities = 10/17 (58%), Positives = 12/17 (70%), Frame = +1
Query: 571 FPSLQGGPQHQFGFSLA 621
FPSLQGGP + +LA
Sbjct: 419 FPSLQGGPHNNHIAALA 435
>gi|12324475|gb|AAG52195.1|AC021199_1 (AC021199) putative
hydroxymethyltransferase; 49598-47322 [Arabidopsis thaliana]
Length = 578
Frame 3 hits (HSPs): ________________
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | 578
0 150 300 450
Plus Strand HSPs:
Score = 516 (181.6 bits), Expect = 8.8e-52, Sum P(2) = 8.8e-52
Identities = 100/173 (57%), Positives = 123/173 (71%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
++ WGVNVQPYS + ANFA YT +L P +RIMGLD PSGGH++HGY T GG ISA SI
Sbjct: 199 ESDKWGVNVQPYSCTSANFAVYTGLLLPGERIMGLDSPSGGHMSHGYCTPGGKKISAASI 258
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S PYKVN TGYIDYD+LE+KAL +RPK++ICGGS+YPRDWD+ R R+IADKCGA+L
Sbjct: 259 FFESFPYKVNPQTGYIDYDKLEDKALDYRPKILICGGSSYPRDWDFARVRQIADKCGAVL 318
Query: 369 LLRXGAHXRPCWPPKN*T-PFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNPQKR 524
+ AH K + PF +C IVT+TTHK G F GP +K+
Sbjct: 319 MCDM-AHISGLVATKECSNPFDHCDIVTSTTHKGLRGPRGGIIFYRRGPKIRKQ 371
Score = 48 (16.9 bits), Expect = 8.8e-52, Sum P(2) = 8.8e-52
Identities = 10/17 (58%), Positives = 12/17 (70%), Frame = +1
Query: 571 FPSLQGGPQHQFGFSLA 621
FPSLQGGP + +LA
Sbjct: 395 FPSLQGGPHNNHIAALA 411
>gi|7433550|pir||T05362 glycine hydroxymethyltransferase (EC 2.1.2.1) F8B4.220
- Arabidopsis thaliana >gi|4049354|emb|CAA22579.1| (AL034567)
glycine hydroxymethyltransferase (EC 2.1.2.1)-like protein
[Arabidopsis thaliana] >gi|7270156|emb|CAB79969.1| (AL161581)
glycine hydroxymethyltransferase (EC 2.1.2.1)-like protein
[Arabidopsis thaliana]
Length = 462
Frame 3 hits (HSPs): __________________
Frame 2 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | | 462
0 150 300 450
Plus Strand HSPs:
Score = 472 (166.2 bits), Expect = 1.6e-46, Sum P(2) = 1.6e-46
Identities = 94/163 (57%), Positives = 113/163 (69%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D+ WGVNVQP SGSPANFA YTA+L+PHDRIMGLDLP GGHL+HG+ T+ +S TSI
Sbjct: 97 DSTKWGVNVQPLSGSPANFAVYTAILSPHDRIMGLDLPHGGHLSHGFMTAK-RRVSGTSI 155
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF S+PY+++ +TG +DYD LE+ A FRPKLII G SAY RD+DY R R+IAD GA L
Sbjct: 156 YFESMPYRLDESTGIVDYDMLEKTATLFRPKLIIAGASAYSRDFDYPRMRKIADSVGAFL 215
Query: 369 LLRXGAHXRPCWPPKN*T-PFXYCXIVTTTTHKTCXVHXXGXXF 497
++ AH PF YC IVTTTTHK+ G F
Sbjct: 216 MMDM-AHISGLVAASVVADPFEYCDIVTTTTHKSLRGPRGGMIF 258
Score = 42 (14.8 bits), Expect = 1.6e-46, Sum P(2) = 1.6e-46
Identities = 7/14 (50%), Positives = 10/14 (71%), Frame = +2
Query: 464 NLXGPXGGXXFYRR 505
+L GP GG F+R+
Sbjct: 248 SLRGPRGGMIFFRK 261
>gi|5821827|pdb|1BJ4|A Chain A, Recombinant Serine Hydroxymethyltransferase
(Human)
Length = 470
Frame 3 hits (HSPs): _____________________
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | 470
0 150 300 450
Plus Strand HSPs:
Score = 465 (163.7 bits), Expect = 8.7e-46, Sum P(2) = 8.7e-46
Identities = 103/192 (53%), Positives = 120/192 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 97 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 155
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F PKLII G S Y R+ +Y R R+IAD+ GA L
Sbjct: 156 FFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYL 215
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNPQKRAPEXRF 542
+ AH +PF +C +VTTTTHKT G F +G A
Sbjct: 216 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEI 274
Query: 543 LFQ-EKLTLGVPFP 581
L+ E L FP
Sbjct: 275 LYNLESLINSAVFP 288
Score = 42 (14.8 bits), Expect = 8.7e-46, Sum P(2) = 8.7e-46
Identities = 7/10 (70%), Positives = 8/10 (80%), Frame = +1
Query: 571 FPSLQGGPQH 600
FP LQGGP +
Sbjct: 287 FPGLQGGPHN 296
>gi|8388673|emb|CAB94023.1| (AL358652) (mitochondrial?) serine
hydroxymethyltransferase [Leishmania major]
Length = 465
Frame 3 hits (HSPs): __________________
Frame 2 hits (HSPs): _____
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | 465
0 150 300 450
Plus Strand HSPs:
Score = 460 (161.9 bits), Expect = 1.1e-45, Sum P(2) = 1.1e-45
Identities = 96/163 (58%), Positives = 109/163 (66%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQPYSGSPANFA YTA+L PH RIMGLDLPSGGHLTHG+YT +SATSI
Sbjct: 89 DPGEWGVNVQPYSGSPANFAVYTALLEPHSRIMGLDLPSGGHLTHGFYTPK-KKVSATSI 147
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF S PY V G IDYD LE AL FRPK+II G SAY RD+DY+RFR + D+ G+LL
Sbjct: 148 YFESFPYHVKED-GLIDYDALESVALVFRPKMIITGASAYARDFDYERFRHVCDEVGSLL 206
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF Y +VTTTTHK+ G F
Sbjct: 207 FMDM-AHTAGLIAGGVLKSPFPYADVVTTTTHKSLRGPRAGMIF 249
Score = 46 (16.2 bits), Expect = 1.1e-45, Sum P(2) = 1.1e-45
Identities = 14/45 (31%), Positives = 21/45 (46%), Frame = +2
Query: 464 NLXGPXGGXXFYRRAQPPKKGAXKXFFISRKINFGGSLPCRVGPN 598
+L GP G FYR+ K I++ + F G C+ GP+
Sbjct: 239 SLRGPRAGMIFYRKKDRQGKPTDHESRINQAV-FPG---CQGGPH 279
Score = 44 (15.5 bits), Expect = 1.8e-45, Sum P(2) = 1.8e-45
Identities = 10/19 (52%), Positives = 13/19 (68%), Frame = +1
Query: 571 FPSLQGGP-QHQFGFSLAKQ 627
FP QGGP +HQ ++A Q
Sbjct: 271 FPGCQGGPHEHQIA-AIATQ 289
>gi|1707994|sp|P35623|GLYC_SHEEP SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC
(SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
>gi|2136860|pir||S65688 glycine hydroxymethyltransferase (EC
2.1.2.1) - sheep >gi|7433543|pir||A40202 glycine
hydroxymethyltransferase (EC 2.1.2.1), cytosolic - sheep
>gi|2407962|emb|CAA56326.1| (X80024) serine hydroxymethyl
transferase [Ovis aries]
Length = 484
Frame 3 hits (HSPs): _____________________
Frame 1 hits (HSPs): __
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 484
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 42..70
BLOCKS BL00096B: Serine hydroxymethyltransferas 95..127
BLOCKS BL00096C: Serine hydroxymethyltransferas 128..151
BLOCKS BL00096D: Serine hydroxymethyltransferas 177..217
BLOCKS BL00096E: Serine hydroxymethyltransferas 218..260
BLOCKS BL00096F: Serine hydroxymethyltransferas 290..330
BLOCKS BL00096G: Serine hydroxymethyltransferas 384..421
Entrez acetylation site 2
Entrez binding site: PYRIDOXAL PHOSPHATE. 257
PFAM SHMT: Serine hydroxymethyltransferase 25..424
PRODOM PD090147: GLYC_SHEEP 1..23
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 25..423
PRODOM PD023539: GLYC(3) 425..482
PROSITE SHMT: Serine hydroxymethyltransferase py 249..265
__________________
Plus Strand HSPs:
Score = 457 (160.9 bits), Expect = 6.0e-45, Sum P(2) = 6.0e-45
Identities = 101/192 (52%), Positives = 121/192 (63%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPECWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F P+LII G S Y R+ DY R R+IAD GA L
Sbjct: 166 FFESMPYKVNPDTGYINYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF----TEGPNPQKRAPE 533
+ AH +PF +C +V+TTTHKT G F +P K E
Sbjct: 226 MADM-AHISGLVAAGVVPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDP-KTGKE 283
Query: 534 XRFLFQEKLTLGVPFP 581
R+ + + V FP
Sbjct: 284 TRYNLESLINSAV-FP 298
Score = 42 (14.8 bits), Expect = 6.0e-45, Sum P(2) = 6.0e-45
Identities = 7/10 (70%), Positives = 8/10 (80%), Frame = +1
Query: 571 FPSLQGGPQH 600
FP LQGGP +
Sbjct: 297 FPGLQGGPHN 306
>gi|2136861|pir||S72452 glycine hydroxymethyltransferase (EC 2.1.2.1) - sheep
Length = 484
Frame 3 hits (HSPs): _____________________
Frame 1 hits (HSPs): __
Annotated Domains: ___
__________________________________________________
Database sequence: | | | | | 484
0 150 300 450
__________________
Annotated Domains:
PROSITE SHMT: Serine hydroxymethyltransferase py 249..265
__________________
Plus Strand HSPs:
Score = 457 (160.9 bits), Expect = 6.0e-45, Sum P(2) = 6.0e-45
Identities = 101/192 (52%), Positives = 121/192 (63%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPECWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F P+LII G S Y R+ DY R R+IAD GA L
Sbjct: 166 FFESMPYKVNPDTGYINYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF----TEGPNPQKRAPE 533
+ AH +PF +C +V+TTTHKT G F +P K E
Sbjct: 226 MADM-AHISGLVAAGVVPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDP-KTGKE 283
Query: 534 XRFLFQEKLTLGVPFP 581
R+ + + V FP
Sbjct: 284 TRYNLESLINSAV-FP 298
Score = 42 (14.8 bits), Expect = 6.0e-45, Sum P(2) = 6.0e-45
Identities = 7/10 (70%), Positives = 8/10 (80%), Frame = +1
Query: 571 FPSLQGGPQH 600
FP LQGGP +
Sbjct: 297 FPGLQGGPHN 306
>gi|7007323|emb|CAB72302.2| (AL138973) serine hydroxymethyltransferase
[Leishmania major]
Length = 480
Frame 3 hits (HSPs): __________________
Frame 1 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | | 480
0 150 300 450
Plus Strand HSPs:
Score = 451 (158.8 bits), Expect = 7.7e-45, Sum P(2) = 7.7e-45
Identities = 88/163 (53%), Positives = 110/163 (67%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
DA WGV+VQPYSGSPAN A YTA+L PHDR+MGL L +GGHLTHG+YT+ +SA+SI
Sbjct: 111 DAALWGVSVQPYSGSPANLAVYTALLRPHDRMMGLSLQAGGHLTHGFYTAT-KRLSASSI 169
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F SLPY + + G +DYD+L A ++P+LII GGSAYPRDWDYKR+REI D GA
Sbjct: 170 FFESLPYSI-TPKGLVDYDQLAYLADIYKPRLIIAGGSAYPRDWDYKRYREICDSVGAYF 228
Query: 369 LLRXGAHXRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXF 497
++ ++ PF Y +VTTTTHKT G F
Sbjct: 229 MVDMSHFSGLVAAREHNDPFEYADVVTTTTHKTLRGPRSGMIF 271
Score = 47 (16.5 bits), Expect = 7.7e-45, Sum P(2) = 7.7e-45
Identities = 11/19 (57%), Positives = 13/19 (68%), Frame = +1
Query: 571 FPSLQGGPQ-HQFGFSLAKQ 627
FP+LQGGP HQ +A Q
Sbjct: 294 FPALQGGPHLHQIA-GIATQ 312
>gi|543154|pir||S40497 serine hydroxymethyltransferase - sheep
>gi|545298|gb|AAB29853.1| serine hydroxymethyltransferase, SHMT {EC
2.1.2.1} [sheep, liver, cytosol, Peptide, 483 aa]
Length = 483
Frame 3 hits (HSPs): _____________________
Frame 1 hits (HSPs): __
Annotated Domains: ___
__________________________________________________
Database sequence: | | | | | 483
0 150 300 450
__________________
Annotated Domains:
PROSITE SHMT: Serine hydroxymethyltransferase py 248..264
__________________
Plus Strand HSPs:
Score = 442 (155.6 bits), Expect = 2.3e-43, Sum P(2) = 2.3e-43
Identities = 100/192 (52%), Positives = 120/192 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + +GVN QPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 106 DPECFGVNYQPYSGSPANFAVYTALVEPHARIMGLDLPDGGHLTHGFMTDK-KKISATSI 164
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+ YKVN TGYI+YD+LEE A F PKLII G S Y R+ DY R R+IAD+ GA L
Sbjct: 165 FFESMAYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADENGAYL 224
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNP--QKRAPEX 536
+ AH +PF +C +VTTTTHKT G F +G K E
Sbjct: 225 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKET 283
Query: 537 RFLFQEKLTLGVPFP 581
R+ + + V FP
Sbjct: 284 RYNLESLINSAV-FP 297
Score = 42 (14.8 bits), Expect = 2.3e-43, Sum P(2) = 2.3e-43
Identities = 7/10 (70%), Positives = 8/10 (80%), Frame = +1
Query: 571 FPSLQGGPQH 600
FP LQGGP +
Sbjct: 296 FPGLQGGPHN 305
>gi|1707992|sp|P50432|GLYC_CAEEL SERINE HYDROXYMETHYLTRANSFERASE (SERINE
METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
>gi|485099|gb|AAB53830.1| (U00048) Contains similarity to Pfam
domain: PF00464 (SHMT), Score=954.1, E-value=9.9e-287, N=1
[Caenorhabditis elegans]
Length = 484
Frame 3 hits (HSPs): ________________
Frame 2 hits (HSPs): _____
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 484
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 46..74
BLOCKS BL00096B: Serine hydroxymethyltransferas 99..131
BLOCKS BL00096C: Serine hydroxymethyltransferas 132..155
BLOCKS BL00096D: Serine hydroxymethyltransferas 181..221
BLOCKS BL00096E: Serine hydroxymethyltransferas 222..264
BLOCKS BL00096F: Serine hydroxymethyltransferas 293..333
BLOCKS BL00096G: Serine hydroxymethyltransferas 387..424
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 26..458
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 260
PFAM SHMT: Serine hydroxymethyltransferase 29..427
PRODOM PD090151: GLYC_CAEEL 1..30
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 32..426
PRODOM PD116684: GLYC_CAEEL 428..483
PROSITE SHMT: Serine hydroxymethyltransferase py 252..268
__________________
Plus Strand HSPs:
Score = 433 (152.4 bits), Expect = 2.9e-43, Sum P(2) = 2.9e-43
Identities = 89/153 (58%), Positives = 106/153 (69%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SGSPANFA YTA++ + RIMGLDLP GGHLTHG++T +SATS
Sbjct: 110 DPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPDGGHLTHGFFTPA-RKVSATSE 168
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F SLPYKV+ TTG IDYD+LE+ A+ FRPK II G S Y R DY+RFR+IA K GA L
Sbjct: 169 FFQSLPYKVDPTTGLIDYDKLEQNAMLFRPKAIIAGVSCYARHLDYERFRKIATKAGAYL 228
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKT 467
+ AH +PF Y +VTTTTHK+
Sbjct: 229 MSDM-AHISGLVAAGLIPSPFEYSDVVTTTTHKS 261
Score = 50 (17.6 bits), Expect = 2.9e-43, Sum P(2) = 2.9e-43
Identities = 12/35 (34%), Positives = 16/35 (45%), Frame = +2
Query: 464 NLXGPXGGXXFYRRA--QPPKKGAXKXFFISRKIN 562
+L GP G FYR+ KG + + KIN
Sbjct: 261 SLRGPRGALIFYRKGVRSTNAKGVDTLYDLEEKIN 295
>gi|232178|sp|P07511|GLYC_RABIT SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC
(SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
>gi|2144397|pir||XYRBSC glycine hydroxymethyltransferase (EC
2.1.2.1), cytosolic - rabbit >gi|1537|emb|CAA77870.1| (Z11846)
cytosolic serine hydroxymethyltransferase [Oryctolagus cuniculus]
Length = 484
Frame 3 hits (HSPs): __________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 484
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 42..70
BLOCKS BL00096B: Serine hydroxymethyltransferas 95..127
BLOCKS BL00096C: Serine hydroxymethyltransferas 128..151
BLOCKS BL00096D: Serine hydroxymethyltransferas 177..217
BLOCKS BL00096E: Serine hydroxymethyltransferas 218..260
BLOCKS BL00096F: Serine hydroxymethyltransferas 290..330
BLOCKS BL00096G: Serine hydroxymethyltransferas 384..421
Entrez acetylation site 2
Entrez amidation site: DE. 6
Entrez binding site: PYRIDOXAL PHOSPHATE. 257
PFAM SHMT: Serine hydroxymethyltransferase 25..424
PRODOM PD090146: GLYC_RABIT 1..23
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 25..423
PRODOM PD023539: GLYC(3) 425..482
PROSITE SHMT: Serine hydroxymethyltransferase py 249..265
__________________
Plus Strand HSPs:
Score = 465 (163.7 bits), Expect = 3.9e-43, P = 3.9e-43
Identities = 96/163 (58%), Positives = 108/163 (66%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+ YKVN TGYIDYDRLEE A F PKLII G S Y R+ DY R R+IAD+ GA L
Sbjct: 166 FFESMAYKVNPDTGYIDYDRLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ +PF +C +VTTTTHKT G F
Sbjct: 226 MADMAHISGLVVAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 268
>gi|5107549|pdb|1CJ0|A Chain A, Crystal Structure Of Rabbit Cytosolic Serine
Hydroxymethyltransferase At 2.8 Angstrom Resolution
>gi|5107550|pdb|1CJ0|B Chain B, Crystal Structure Of Rabbit
Cytosolic Serine Hydroxymethyltransferase At 2.8 Angstrom
Resolution
Length = 470
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | 470
0 150 300 450
Plus Strand HSPs:
Score = 465 (163.7 bits), Expect = 3.9e-43, P = 3.9e-43
Identities = 96/163 (58%), Positives = 108/163 (66%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 93 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 151
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+ YKVN TGYIDYDRLEE A F PKLII G S Y R+ DY R R+IAD+ GA L
Sbjct: 152 FFESMAYKVNPDTGYIDYDRLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYL 211
Query: 369 LLRXGAHXRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ +PF +C +VTTTTHKT G F
Sbjct: 212 MADMAHISGLVVAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 254
>gi|4759106 ref|NP_004160.1| serine hydroxymethyltransferase 1 (soluble);
cytoplasmic serine hydroxymethyltransferase [Homo sapiens]
>gi|11427860 ref|XP_008637.1| serine hydroxymethyltransferase 1
(soluble) [Homo sapiens] >gi|462184|sp|P34896|GLYC_HUMAN SERINE
HYDROXYMETHYLTRANSFERASE, CYTOSOLIC (SERINE METHYLASE) (GLYCINE
HYDROXYMETHYLTRANSFERASE) (SHMT) >gi|539603|pir||A46746 glycine
hydroxymethyltransferase (EC 2.1.2.1), cytosolic - human
>gi|307422|gb|AAA63257.1| (L11931) serine hydroxymethyltransferase
[Homo sapiens] >gi|438636|gb|AAA36020.1| (L23928) serine
hydroxymethyltransferase [Homo sapiens] >gi|5830436|emb|CAB54838.1|
(Y14485) cytosolic serine hydroxymethyltransferase [Homo sapiens]
Length = 483
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | 483
0 150 300 450
Plus Strand HSPs:
Score = 462 (162.6 bits), Expect = 8.2e-43, P = 8.2e-43
Identities = 96/163 (58%), Positives = 111/163 (68%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F PKLII G S Y R+ +Y R R+IAD+ GA L
Sbjct: 166 FFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF +C +VTTTTHKT G F
Sbjct: 226 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 268
>gi|438634|gb|AAA36018.1| (L23928) serine hydroxymethyltransferase [Homo
sapiens]
Length = 444
Frame 3 hits (HSPs): ____________________
__________________________________________________
Database sequence: | | | | 444
0 150 300
Plus Strand HSPs:
Score = 462 (162.6 bits), Expect = 8.2e-43, P = 8.2e-43
Identities = 96/163 (58%), Positives = 111/163 (68%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F PKLII G S Y R+ +Y R R+IAD+ GA L
Sbjct: 166 FFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF +C +VTTTTHKT G F
Sbjct: 226 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 268
>gi|438635|gb|AAA36019.1| (L23928) serine hydroxymethyltransferase [Homo
sapiens]
Length = 403
Frame 3 hits (HSPs): _____________________
__________________________________________________
Database sequence: | | | | 403
0 150 300
Plus Strand HSPs:
Score = 462 (162.6 bits), Expect = 8.2e-43, P = 8.2e-43
Identities = 96/163 (58%), Positives = 111/163 (68%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F PKLII G S Y R+ +Y R R+IAD+ GA L
Sbjct: 166 FFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF +C +VTTTTHKT G F
Sbjct: 226 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 268
>gi|5830440|emb|CAB54840.1| (Y14487) cytosolic serine hydroxymethyltransferase
[Homo sapiens]
Length = 347
Frame 3 hits (HSPs): ________________________
__________________________________________________
Database sequence: | | | | 347
0 150 300
Plus Strand HSPs:
Score = 462 (162.6 bits), Expect = 8.2e-43, P = 8.2e-43
Identities = 96/163 (58%), Positives = 111/163 (68%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 107 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 165
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TGYI+YD+LEE A F PKLII G S Y R+ +Y R R+IAD+ GA L
Sbjct: 166 FFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYL 225
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF +C +VTTTTHKT G F
Sbjct: 226 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 268
>gi|6677943 ref|NP_033197.1| serine hydroxymethyl transferase 1 (soluble) [Mus
musculus] >gi|2137763|pir||JC4958 serine hydroxymethyltransferase
(EC 2.1.2.-) 1 - mouse >gi|1139579|emb|CAA64225.1| (X94478)
hydroxymethyltransferase [Mus musculus]
Length = 309
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | | | | | 309
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 456 (160.5 bits), Expect = 3.5e-42, P = 3.5e-42
Identities = 96/163 (58%), Positives = 109/163 (66%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 101 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 159
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKV TGYI+YD+LEE A F PKLII G S Y R+ DY R R+IAD GA L
Sbjct: 160 FFESMPYKVYPETGYINYDQLEENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYL 219
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF +C +VTTTTHKT G F
Sbjct: 220 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 262
>gi|1707993|sp|P50431|GLYC_MOUSE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC
(SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
>gi|2137764|pir||JC4959 serine hydroxymethyltransferase (EC
2.1.2.-) 2 - mouse >gi|1139581|emb|CAA64226.1| (X94479)
hydroxymethyltransferase [Mus musculus]
Length = 316
Frame 3 hits (HSPs): ___________________________
Annotated Domains: _______________________________________________
__________________________________________________
Database sequence: | | | | | | | | 316
0 50 100 150 200 250 300
__________________
Annotated Domains:
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 251
PFAM SHMT: Serine hydroxymethyltransferase 20..315
PROSITE SHMT: Serine hydroxymethyltransferase py 243..259
__________________
Plus Strand HSPs:
Score = 456 (160.5 bits), Expect = 3.5e-42, P = 3.5e-42
Identities = 96/163 (58%), Positives = 109/163 (66%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 101 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSI 159
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKV TGYI+YD+LEE A F PKLII G S Y R+ DY R R+IAD GA L
Sbjct: 160 FFESMPYKVYPETGYINYDQLEENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYL 219
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
+ AH +PF +C +VTTTTHKT G F
Sbjct: 220 MADM-AHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIF 262
>gi|109230|pir||A33696 glycine hydroxymethyltransferase (EC 2.1.2.1),
mitochondrial - rabbit
Length = 475
Frame 3 hits (HSPs): _____________________
Annotated Domains: ___
__________________________________________________
Database sequence: | | | | | 475
0 150 300 450
__________________
Annotated Domains:
PROSITE SHMT: Serine hydroxymethyltransferase py 243..259
__________________
Plus Strand HSPs:
Score = 448 (157.7 bits), Expect = 2.5e-41, P = 2.5e-41
Identities = 101/193 (52%), Positives = 121/193 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQPYSGSPAN AAYTA+L PHDRIMGLDLP GGHLTHGY S +SATSI
Sbjct: 101 DPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYM-SDVKRVSATSI 159
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYK+N TG IDY++L A FRP+LII G SAY R DY R RE+ D+ A L
Sbjct: 160 FFESMPYKLNPQTGLIDYEQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHL 219
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNP--QKRAPEX 536
L AH K +PF + +VTTTTHKT G F +G K E
Sbjct: 220 LADM-AHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVRTVDPKTGQEI 278
Query: 537 RFLFQEKLTLGVPFPA 584
+ F++++ V FP+
Sbjct: 279 PYTFEDRINFAV-FPS 293
>gi|2507389|sp|P14519|GLYM_RABIT SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|1848137|emb|CAA62998.1| (X91902) serine
hydroxymethyltransferase [Oryctolagus cuniculus]
Length = 504
Frame 3 hits (HSPs): ____________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 504
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 66..94
BLOCKS BL00096B: Serine hydroxymethyltransferas 119..151
BLOCKS BL00096C: Serine hydroxymethyltransferas 152..175
BLOCKS BL00096D: Serine hydroxymethyltransferas 201..241
BLOCKS BL00096E: Serine hydroxymethyltransferas 242..284
BLOCKS BL00096F: Serine hydroxymethyltransferas 314..354
BLOCKS BL00096G: Serine hydroxymethyltransferas 408..445
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 17..449
Entrez binding site: PYRIDOXAL PHOSPHATE. 280
PFAM SHMT: Serine hydroxymethyltransferase 49..448
PRODOM PD033777: GLYM(2) 1..47
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 49..447
PRODOM PD038299: GLYM(2) 449..503
PROSITE SHMT: Serine hydroxymethyltransferase py 272..288
__________________
Plus Strand HSPs:
Score = 448 (157.7 bits), Expect = 2.5e-41, P = 2.5e-41
Identities = 101/193 (52%), Positives = 121/193 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQPYSGSPAN AAYTA+L PHDRIMGLDLP GGHLTHGY S +SATSI
Sbjct: 130 DPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYM-SDVKRVSATSI 188
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYK+N TG IDY++L A FRP+LII G SAY R DY R RE+ D+ A L
Sbjct: 189 FFESMPYKLNPQTGLIDYEQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHL 248
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNP--QKRAPEX 536
L AH K +PF + +VTTTTHKT G F +G K E
Sbjct: 249 LADM-AHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVRTVDPKTGQEI 307
Query: 537 RFLFQEKLTLGVPFPA 584
+ F++++ V FP+
Sbjct: 308 PYTFEDRINFAV-FPS 322
>gi|7290652|gb|AAF46101.1| (AE003435) CG3011 gene product [Drosophila
melanogaster]
Length = 537
Frame 3 hits (HSPs): ___________________
__________________________________________________
Database sequence: | | | | | 537
0 150 300 450
Plus Strand HSPs:
Score = 447 (157.4 bits), Expect = 3.2e-41, P = 3.2e-41
Identities = 100/192 (52%), Positives = 119/192 (61%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + WGVNVQPYSGSPAN A YT V PHDRIMGLDLP GGHLTHG++T ISATSI
Sbjct: 162 DDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPT-KKISATSI 220
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYKVN TG IDYD+L E A FRP++II G S Y R DY RFR+I D GA L
Sbjct: 221 FFESMPYKVNPETGIIDYDKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYL 280
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXFTEGPNPQKRAPEXRFL 545
+ AH +PF + IVTTTTHKT G F +A + L
Sbjct: 281 MADM-AHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRAGVIFFRKGVRSTKANGDKVL 339
Query: 546 F--QEKLTLGVPFPA 584
+ +E++ V FP+
Sbjct: 340 YDLEERINQAV-FPS 353
>gi|539602|pir||B46746 glycine hydroxymethyltransferase (EC 2.1.2.1) precursor,
mitochondrial - human (fragment) >gi|703093|gb|AAA63258.1| (L11932)
serine hydroxymethyltransferase [Homo sapiens]
Length = 474
Frame 3 hits (HSPs): _____________________
Annotated Domains: ___
__________________________________________________
Database sequence: | | | | | 474
0 150 300 450
__________________
Annotated Domains:
PROSITE SHMT: Serine hydroxymethyltransferase py 242..258
__________________
Plus Strand HSPs:
Score = 445 (156.6 bits), Expect = 5.2e-41, P = 5.2e-41
Identities = 102/193 (52%), Positives = 121/193 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQPYSGSPAN A YTA+L PHDRIMGLDLP GGHLTHGY S ISATSI
Sbjct: 100 DPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYM-SDVKRISATSI 158
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYK+N TG IDY++L A FRP+LII G SAY R DY R RE+ D+ A L
Sbjct: 159 FFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHL 218
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF----TEGPNPQKRAPE 533
L AH K +PF + IVTTTTHKT G F + +P K E
Sbjct: 219 LADM-AHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDP-KTGRE 276
Query: 534 XRFLFQEKLTLGVPFPA 584
+ F++++ V FP+
Sbjct: 277 ILYTFEDRINFAV-FPS 292
>gi|4885595 ref|NP_005403.1| serine hydroxymethyltransferase 2 (mitochondrial)
[Homo sapiens] >gi|746436|gb|AAA64572.1| (U23143) mitochondrial
serine hydroxymethyltransferase [Homo sapiens]
Length = 483
Frame 3 hits (HSPs): _____________________
__________________________________________________
Database sequence: | | | | | 483
0 150 300 450
Plus Strand HSPs:
Score = 445 (156.6 bits), Expect = 5.2e-41, P = 5.2e-41
Identities = 102/193 (52%), Positives = 121/193 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQPYSGSPAN A YTA+L PHDRIMGLDLP GGHLTHGY S ISATSI
Sbjct: 109 DPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYM-SDVKRISATSI 167
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYK+N TG IDY++L A FRP+LII G SAY R DY R RE+ D+ A L
Sbjct: 168 FFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHL 227
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF----TEGPNPQKRAPE 533
L AH K +PF + IVTTTTHKT G F + +P K E
Sbjct: 228 LADM-AHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDP-KTGRE 285
Query: 534 XRFLFQEKLTLGVPFPA 584
+ F++++ V FP+
Sbjct: 286 IPYTFEDRINFAV-FPS 301
>gi|6226865|sp|P34897|GLYM_HUMAN SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT)
Length = 504
Frame 3 hits (HSPs): ____________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 504
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 45..73
BLOCKS BL00096B: Serine hydroxymethyltransferas 98..130
BLOCKS BL00096C: Serine hydroxymethyltransferas 131..154
BLOCKS BL00096D: Serine hydroxymethyltransferas 180..220
BLOCKS BL00096E: Serine hydroxymethyltransferas 221..263
BLOCKS BL00096F: Serine hydroxymethyltransferas 293..333
BLOCKS BL00096G: Serine hydroxymethyltransferas 387..424
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 25..457
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 280
PFAM SHMT: Serine hydroxymethyltransferase 28..427
PRODOM PD033777: GLYM(2) 1..47
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 49..447
PRODOM PD038299: GLYM(2) 449..503
PROSITE SHMT: Serine hydroxymethyltransferase py 272..288
__________________
Plus Strand HSPs:
Score = 445 (156.6 bits), Expect = 5.2e-41, P = 5.2e-41
Identities = 102/193 (52%), Positives = 121/193 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQPYSGSPAN A YTA+L PHDRIMGLDLP GGHLTHGY S ISATSI
Sbjct: 130 DPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYM-SDVKRISATSI 188
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S+PYK+N TG IDY++L A FRP+LII G SAY R DY R RE+ D+ A L
Sbjct: 189 FFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHL 248
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF----TEGPNPQKRAPE 533
L AH K +PF + IVTTTTHKT G F + +P K E
Sbjct: 249 LADM-AHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDP-KTGRE 306
Query: 534 XRFLFQEKLTLGVPFPA 584
+ F++++ V FP+
Sbjct: 307 IPYTFEDRINFAV-FPS 322
>gi|11514068|pdb|1EJI|A Chain A, Recombinant Serine Hydroxymethyltransferase
(Mouse) >gi|11514069|pdb|1EJI|B Chain B, Recombinant Serine
Hydroxymethyltransferase (Mouse) >gi|11514070|pdb|1EJI|C Chain C,
Recombinant Serine Hydroxymethyltransferase (Mouse)
>gi|11514071|pdb|1EJI|D Chain D, Recombinant Serine
Hydroxymethyltransferase (Mouse)
Length = 478
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | 478
0 150 300 450
Plus Strand HSPs:
Score = 445 (156.6 bits), Expect = 5.2e-41, P = 5.2e-41
Identities = 95/163 (58%), Positives = 106/163 (65%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RI GLDLP GGHLTHG+ T ISATSI
Sbjct: 101 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIXGLDLPDGGHLTHGFXTDK-KKISATSI 159
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F S PYKV TGYI+YD+LEE A F PKLII G S Y R+ DY R R+IAD GA L
Sbjct: 160 FFESXPYKVYPETGYINYDQLEENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYL 219
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF 497
AH +PF +C +VTTTTHKT G F
Sbjct: 220 XA-DXAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGXIF 262
>gi|1346156|sp|P49358|GLYN_FLAPR SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
2 PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|481943|pir||S40213 glycine hydroxymethyltransferase (EC
2.1.2.1) isoform 2 - Flaveria pringlei >gi|437997|emb|CAA81079.1|
(Z25860) glycine hydroxymethyltransferase [Flaveria pringlei]
Length = 517
Frame 3 hits (HSPs): ___________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 517
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 73..101
BLOCKS BL00096B: Serine hydroxymethyltransferas 126..158
BLOCKS BL00096C: Serine hydroxymethyltransferas 159..182
BLOCKS BL00096D: Serine hydroxymethyltransferas 208..248
BLOCKS BL00096E: Serine hydroxymethyltransferas 249..291
BLOCKS BL00096F: Serine hydroxymethyltransferas 320..360
BLOCKS BL00096G: Serine hydroxymethyltransferas 414..451
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 287
PFAM SHMT: Serine hydroxymethyltransferase 56..454
PRODOM PD016315: GLYM(3) GLYN(1) 1..54
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 56..450
PRODOM PD013734: GLYM(3) GLYN(1) O04952(1) 454..515
PROSITE SHMT: Serine hydroxymethyltransferase py 279..295
__________________
Plus Strand HSPs:
Score = 441 (155.2 bits), Expect = 1.4e-40, P = 1.4e-40
Identities = 96/191 (50%), Positives = 121/191 (63%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
DA WGVNVQP SGSPANF YTA+L HDRIM LDLP GGHL+HGY T ISA SI
Sbjct: 137 DAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLSHGYQTDT-KKISAVSI 195
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F ++PY++N +TGYIDYD+LE+ A FRPKLI+ G SAY R +DY R R++ DK A+L
Sbjct: 196 FFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYDYARIRKVCDKQKAIL 255
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEGPNP-QKRAPEXR 539
L AH +PF Y +VTTTTHK+ F +G K+ E
Sbjct: 256 LADM-AHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFRKGVKEVNKQGKEVL 314
Query: 540 FLFQEKLTLGVPFP 581
+ +++K+ V FP
Sbjct: 315 YDYEDKINQAV-FP 327
>gi|462187|sp|P34899|GLYM_PEA SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|282928|pir||A42906 glycine hydroxymethyltransferase (EC
2.1.2.1) - garden pea >gi|169158|gb|AAA33687.1| (M87649) serine
hydroxymethyltransferase [Pisum sativum]
Length = 518
Frame 3 hits (HSPs): ___________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 518
0 150 300 450
__________________
Annotated Domains:
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 287
PFAM SHMT: Serine hydroxymethyltransferase 56..454
PRODOM PD016315: GLYM(3) GLYN(1) 1..54
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 60..452
PRODOM PD013734: GLYM(3) GLYN(1) O04952(1) 454..516
PROSITE SHMT: Serine hydroxymethyltransferase py 279..295
__________________
Plus Strand HSPs:
Score = 435 (153.1 bits), Expect = 5.9e-40, P = 5.9e-40
Identities = 94/191 (49%), Positives = 121/191 (63%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SGSP+NF YTA+L PHDRIM LDLP GGHL+HGY T ISA SI
Sbjct: 137 DPAKWGVNVQPLSGSPSNFQVYTALLKPHDRIMALDLPHGGHLSHGYQTDT-KKISAVSI 195
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F ++PY+++ +TGYIDYD+LE+ A FRPKLI+ G SAY R +DY R R++ DK A+L
Sbjct: 196 FFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYDYARIRKVCDKQKAVL 255
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEG-PNPQKRAPEXR 539
L AH +PF Y +VTTTTHK+ F +G K+ E
Sbjct: 256 LADM-AHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFRKGLKEVNKQGKEVF 314
Query: 540 FLFQEKLTLGVPFP 581
+ +++K+ V FP
Sbjct: 315 YDYEDKINQAV-FP 327
>gi|1346155|sp|P49357|GLYM_FLAPR SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
1 PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|481942|pir||S40212 glycine hydroxymethyltransferase (EC
2.1.2.1) isoform 1 - Flaveria pringlei >gi|437995|emb|CAA81078.1|
(Z25859) glycine hydroxymethyltransferase [Flaveria pringlei]
Length = 517
Frame 3 hits (HSPs): ___________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 517
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 73..101
BLOCKS BL00096B: Serine hydroxymethyltransferas 126..158
BLOCKS BL00096C: Serine hydroxymethyltransferas 159..182
BLOCKS BL00096D: Serine hydroxymethyltransferas 208..248
BLOCKS BL00096E: Serine hydroxymethyltransferas 249..291
BLOCKS BL00096F: Serine hydroxymethyltransferas 320..360
BLOCKS BL00096G: Serine hydroxymethyltransferas 414..451
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 53..486
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 287
PFAM SHMT: Serine hydroxymethyltransferase 56..454
PRODOM PD016315: GLYM(3) GLYN(1) 1..54
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 56..450
PRODOM PD013734: GLYM(3) GLYN(1) O04952(1) 454..515
PROSITE SHMT: Serine hydroxymethyltransferase py 279..295
__________________
Plus Strand HSPs:
Score = 433 (152.4 bits), Expect = 9.7e-40, P = 9.7e-40
Identities = 94/191 (49%), Positives = 120/191 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SGSPANF YTA+L HDRIM LDLP GGHL+HGY T ISA SI
Sbjct: 137 DPAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLSHGYQTDT-KKISAVSI 195
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F ++PY++N +TGYIDYD+LE+ A FRPKLI+ G SAY R +DY R R++ DK A++
Sbjct: 196 FFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYDYARIRKVCDKQKAIM 255
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEG-PNPQKRAPEXR 539
L AH +PF Y +VTTTTHK+ F +G K+ E
Sbjct: 256 LADM-AHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFRKGLKEVNKQGKEVF 314
Query: 540 FLFQEKLTLGVPFP 581
+ +++K+ V FP
Sbjct: 315 YDYEDKINQAV-FP 327
>gi|1346154|sp|Q10104|GLY1_SCHPO PROBABLE SERINE HYDROXYMETHYLTRANSFERASE,
CYTOSOLIC (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|7493372|pir||T37918 serine hydroxymethyltransferase -
fission yeast (Schizosaccharomyces pombe)
>gi|1122369|emb|CAA92384.1| (Z68198) serine
hydroxymethyltransferase [Schizosaccharomyces pombe]
Length = 472
Frame 3 hits (HSPs): _____________________
Annotated Domains: _________________________________________________
__________________________________________________
Database sequence: | | | | | 472
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 35..63
BLOCKS BL00096B: Serine hydroxymethyltransferas 88..120
BLOCKS BL00096C: Serine hydroxymethyltransferas 121..144
BLOCKS BL00096D: Serine hydroxymethyltransferas 170..210
BLOCKS BL00096E: Serine hydroxymethyltransferas 211..253
BLOCKS BL00096F: Serine hydroxymethyltransferas 282..322
BLOCKS BL00096G: Serine hydroxymethyltransferas 376..413
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 15..451
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 249
PFAM SHMT: Serine hydroxymethyltransferase 18..416
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 18..415
PRODOM PD116682: GLY1_SCHPO 417..471
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 429..436
PROSITE SHMT: Serine hydroxymethyltransferase py 241..257
__________________
Plus Strand HSPs:
Score = 433 (152.4 bits), Expect = 9.7e-40, P = 9.7e-40
Identities = 95/191 (49%), Positives = 116/191 (60%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + WGVNVQP+SGSPAN AY AV+ PHDR+MGLDLP GGHL+HG+ T ISA S
Sbjct: 99 DGEKWGVNVQPHSGSPANLQAYQAVMKPHDRLMGLDLPHGGHLSHGFSTPQ-KAISAVST 157
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF ++PY VN TG IDYD LE+ A+ FRPK+I+ G SAY R DYKR R+I + C A L
Sbjct: 158 YFSTMPYNVNKETGIIDYDSLEKAAIQFRPKVIVAGASAYARLVDYKRMRKITEMCNAYL 217
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNPQ-KRAPEXR 539
L AH +PF Y IVTTTTHK+ F +G KR
Sbjct: 218 LCDM-AHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFYRKGTRSHDKRGNPIL 276
Query: 540 FLFQEKLTLGVPFP 581
+ ++K+ V FP
Sbjct: 277 YELEDKINFSV-FP 289
>gi|7433551|pir||T05620 glycine hydroxymethyltransferase (EC 2.1.2.1) F20D10.50
- Arabidopsis thaliana >gi|4467099|emb|CAB37533.1| (AL035538)
glycine hydroxymethyltransferase like protein [Arabidopsis
thaliana] >gi|6899945|emb|CAB71289.1| (AJ271726) serine
hydroxymethyl transferase [Arabidopsis thaliana]
>gi|7270776|emb|CAB80458.1| (AL161592) glycine
hydroxymethyltransferase like protein [Arabidopsis thaliana]
Length = 517
Frame 3 hits (HSPs): ___________________
__________________________________________________
Database sequence: | | | | | 517
0 150 300 450
Plus Strand HSPs:
Score = 433 (152.4 bits), Expect = 9.7e-40, P = 9.7e-40
Identities = 92/191 (48%), Positives = 122/191 (63%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + WGVNVQP SGSPANF YTA+L PH+RIM LDLP GGHL+HGY T ISA SI
Sbjct: 136 DPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALDLPHGGHLSHGYQTDT-KKISAVSI 194
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F ++PY+++ +TGYIDYD++E+ A FRPKLI+ G SAY R +DY R R++ +K A++
Sbjct: 195 FFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAGASAYARLYDYARIRKVCNKQKAVM 254
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEGPNP-QKRAPEXR 539
L AH +PF Y +VTTTTHK+ F +G K+ E
Sbjct: 255 LADM-AHISGLVAANVIPSPFDYADVVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVL 313
Query: 540 FLFQEKLTLGVPFP 581
+ F++K+ V FP
Sbjct: 314 YDFEDKINQAV-FP 326
>gi|7674050|sp|O62585|GLYC_ENCCU SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC
(SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
>gi|3097067|emb|CAA06649.1| (AJ005644) serine
hydroxymethyltransferase [Encephalitozoon cuniculi]
Length = 460
Frame 3 hits (HSPs): _________________
Frame 2 hits (HSPs): ______
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | 460
0 150 300 450
Plus Strand HSPs:
Score = 395 (139.0 bits), Expect = 1.7e-39, Sum P(2) = 1.7e-39
Identities = 87/152 (57%), Positives = 100/152 (65%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D +WGV VQPYSGSPANFA YTAV+ P RIMGLDLPSGGHLTHGY T ISA+S+
Sbjct: 95 DPDAWGVYVQPYSGSPANFAIYTAVVPPGGRIMGLDLPSGGHLTHGYKTKT-RKISASSV 153
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF S PY V S G IDY+ LE+ F P ++ICG SAY RD DYKR + IA + GA L
Sbjct: 154 YFDSRPYTVGSN-GLIDYEGLEKTFTDFLPHILICGYSAYSRDIDYKRLQSIAGRNGAFL 212
Query: 369 LLRXGAHXRPCWPP--KN*TPFXYCXIVTTTTHK 464
+H P N +PF +C IV TTT K
Sbjct: 213 FADI-SHISPLVASGLMN-SPFEHCDIVMTTTQK 244
Score = 52 (18.3 bits), Expect = 1.7e-39, Sum P(2) = 1.7e-39
Identities = 16/46 (34%), Positives = 22/46 (47%), Frame = +2
Query: 467 LXGPXGGXXFYRRAQPPKKGAXKXFFISRKINFGGSLPCRVGPNTN 604
L GP G FYRRA K G + + +INF + GP+ +
Sbjct: 246 LRGPRGALIFYRRAVT-KNG--ETVDLDARINFAVFPMLQGGPHNH 288
Score = 41 (14.4 bits), Expect = 2.5e-38, Sum P(2) = 2.5e-38
Identities = 7/10 (70%), Positives = 8/10 (80%), Frame = +1
Query: 571 FPSLQGGPQH 600
FP LQGGP +
Sbjct: 278 FPMLQGGPHN 287
>gi|3023885|sp|O13425|GLYM_CANAL SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|2282056|gb|AAB64196.1| (AF009965) serine
hydroxymethyl-transferase I [Candida albicans]
Length = 493
Frame 3 hits (HSPs): ________________
Frame 2 hits (HSPs): ____
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 493
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 56..84
BLOCKS BL00096B: Serine hydroxymethyltransferas 109..141
BLOCKS BL00096C: Serine hydroxymethyltransferas 142..165
BLOCKS BL00096D: Serine hydroxymethyltransferas 191..231
BLOCKS BL00096E: Serine hydroxymethyltransferas 232..274
BLOCKS BL00096F: Serine hydroxymethyltransferas 303..343
BLOCKS BL00096G: Serine hydroxymethyltransferas 397..434
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 270
PFAM SHMT: Serine hydroxymethyltransferase 39..437
PRODOM PD090154: GLYM_CANAL 1..37
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 39..436
PRODOM PD116681: GLYM_CANAL 438..492
PROSITE SHMT: Serine hydroxymethyltransferase py 262..278
__________________
Plus Strand HSPs:
Score = 392 (138.0 bits), Expect = 2.2e-39, Sum P(2) = 2.2e-39
Identities = 83/153 (54%), Positives = 100/153 (65%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SG+PAN AY+A+L DRIMGLDLP GGHL+HGY T IS S
Sbjct: 120 DPSQWGVNVQPLSGAPANLYAYSAILEVGDRIMGLDLPHGGHLSHGYQTKT-TKISYISK 178
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF ++PY++N TG IDYD LE+ A FRPK+I+ G SAY R DYKR R+++ + GA L
Sbjct: 179 YFQTMPYRLNEETGIIDYDTLEKNAQLFRPKVIVAGASAYSRVIDYKRMRQLSIRLGAYL 238
Query: 369 LLRXGAHXRPCWPPK-N*TPFXYCXIVTTTTHKT 467
L AH +PF Y IVTTTTHK+
Sbjct: 239 LSDM-AHISGLVSAVVTDSPFPYSDIVTTTTHKS 271
Score = 54 (19.0 bits), Expect = 2.2e-39, Sum P(2) = 2.2e-39
Identities = 13/36 (36%), Positives = 19/36 (52%), Frame = +2
Query: 464 NLXGPXGGXXFYRRA--QPPKKGAXKXFFISRKINF 565
+L GP G F+R+ + KG + + RKINF
Sbjct: 271 SLRGPRGAMIFFRKGIRKVTTKGKEIPYELERKINF 306
>gi|1707998|sp|P50433|GLYM_SOLTU SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|481944|pir||S40218 glycine hydroxymethyltransferase (EC
2.1.2.1) - potato >gi|438247|emb|CAA81082.1| (Z25863) glycine
hydroxymethyltransferase [Solanum tuberosum]
Length = 518
Frame 3 hits (HSPs): ___________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 518
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 73..101
BLOCKS BL00096B: Serine hydroxymethyltransferas 126..158
BLOCKS BL00096C: Serine hydroxymethyltransferas 159..182
BLOCKS BL00096D: Serine hydroxymethyltransferas 208..248
BLOCKS BL00096E: Serine hydroxymethyltransferas 249..291
BLOCKS BL00096F: Serine hydroxymethyltransferas 320..360
BLOCKS BL00096G: Serine hydroxymethyltransferas 414..451
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 287
PFAM SHMT: Serine hydroxymethyltransferase 56..454
PRODOM PD016315: GLYM(3) GLYN(1) 1..54
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 56..452
PRODOM PD013734: GLYM(3) GLYN(1) O04952(1) 454..516
PROSITE SHMT: Serine hydroxymethyltransferase py 279..295
__________________
Plus Strand HSPs:
Score = 429 (151.0 bits), Expect = 2.6e-39, P = 2.6e-39
Identities = 93/191 (48%), Positives = 121/191 (63%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SGSPANF YTA+L PH+RIM LDLP GGHL+HGY T ISA SI
Sbjct: 137 DPAKWGVNVQPLSGSPANFQVYTALLKPHERIMALDLPHGGHLSHGYQTDT-KKISAVSI 195
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F ++PY+++ +TGYIDYD+LE+ A FRPKLI+ G SAY R +DY R R++ +K A+L
Sbjct: 196 FFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYDYDRIRKVCNKQKAIL 255
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXF-TEGPNP-QKRAPEXR 539
L AH +PF Y +VTTTTHK+ F +G K+ E
Sbjct: 256 LADM-AHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFYRKGVKEVNKQGKEVF 314
Query: 540 FLFQEKLTLGVPFP 581
+ +++K+ V FP
Sbjct: 315 YDYEDKINQAV-FP 327
>gi|3183015|sp|O13972|GLY2_SCHPO PROBABLE SERINE HYDROXYMETHYLTRANSFERASE,
CYTOSOLIC (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|7493373|pir||T38353 serine hydroxymethyltransferase -
fission yeast (Schizosaccharomyces pombe)
>gi|2330795|emb|CAB11269.1| (Z98601) serine
hydroxymethyltransferase [Schizosaccharomyces pombe]
Length = 467
Frame 3 hits (HSPs): __________________
Frame 2 hits (HSPs): ____
Annotated Domains: _________________________________________________
__________________________________________________
Database sequence: | | | | | 467
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 29..57
BLOCKS BL00096B: Serine hydroxymethyltransferas 82..114
BLOCKS BL00096C: Serine hydroxymethyltransferas 115..138
BLOCKS BL00096D: Serine hydroxymethyltransferas 164..204
BLOCKS BL00096E: Serine hydroxymethyltransferas 205..247
BLOCKS BL00096F: Serine hydroxymethyltransferas 276..316
BLOCKS BL00096G: Serine hydroxymethyltransferas 370..407
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 243
Entrez Domain: POLY-THR. 238..241
PFAM SHMT: Serine hydroxymethyltransferase 12..410
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 12..409
PRODOM PD116679: GLYC(3) GLY2(1) 411..463
PROSITE SHMT: Serine hydroxymethyltransferase py 235..251
__________________
Plus Strand HSPs:
Score = 389 (136.9 bits), Expect = 3.6e-39, Sum P(2) = 3.6e-39
Identities = 82/153 (53%), Positives = 98/153 (64%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQ SGSPAN Y A++ PH R+MGLDLPSGGHL+HGY T ISA S
Sbjct: 93 DPAKWGVNVQCLSGSPANMQVYQAIMPPHGRLMGLDLPSGGHLSHGYQTDT-KKISAVST 151
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF S+PY+V+ TG IDYD LE A FRPK+++ G SAY R DY R R+IAD A L
Sbjct: 152 YFESMPYRVDPNTGLIDYDMLEHDAQLFRPKILVAGTSAYCRLIDYARMRQIADSVNAYL 211
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKT 467
++ AH +PF Y +VTTTTHK+
Sbjct: 212 VVDM-AHISGLVSAGVIPSPFEYADVVTTTTHKS 244
Score = 55 (19.4 bits), Expect = 3.6e-39, Sum P(2) = 3.6e-39
Identities = 14/36 (38%), Positives = 19/36 (52%), Frame = +2
Query: 464 NLXGPXGGXXFYRRA--QPPKKGAXKXFFISRKINF 565
+L GP G F+RR + KKG + + KINF
Sbjct: 244 SLRGPRGAMIFFRRGLRKHDKKGNPIYYDLEDKINF 279
>gi|7433553|pir||T01759 glycine hydroxymethyltransferase (EC 2.1.2.1)
A_IG002P16.3 - Arabidopsis thaliana >gi|2191159|gb|AAB61045.1|
(AF007270) Similar to serine hydroxymethyltransferase; coded for by
A. thaliana cDNA T42313; coded for by A. thaliana cDNA W43384
[Arabidopsis thaliana]
Length = 532
Frame 3 hits (HSPs): ___________________
__________________________________________________
Database sequence: | | | | | 532
0 150 300 450
Plus Strand HSPs:
Score = 419 (147.5 bits), Expect = 2.9e-38, P = 2.9e-38
Identities = 90/191 (47%), Positives = 120/191 (62%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQ SGSPANF YTA+L PH+RIM LDLP GGHL+HGY T ISA SI
Sbjct: 128 DPSKWGVNVQSLSGSPANFQVYTALLKPHERIMALDLPHGGHLSHGYQTDT-KKISAVSI 186
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
+F ++PY+++ TGYIDYD+LE+ A+ FRPKLI+ G SAY R +DY R R++ +K A++
Sbjct: 187 FFETMPYRLDENTGYIDYDQLEKSAVLFRPKLIVAGASAYARLYDYARIRKVCNKQKAVM 246
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEGPNP-QKRAPEXR 539
L AH +PF Y +VTTTTHK+ F +G K+ E
Sbjct: 247 LADM-AHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGLKEINKQGKEVM 305
Query: 540 FLFQEKLTLGVPFP 581
+ +++++ V FP
Sbjct: 306 YDYEDRINQAV-FP 318
>gi|439120|gb|AAA21023.1| (L22529) serine hydroxymethyltransferase
[Saccharomyces cerevisiae]
Length = 469
Frame 3 hits (HSPs): _________________
__________________________________________________
Database sequence: | | | | | 469
0 150 300 450
Plus Strand HSPs:
Score = 416 (146.4 bits), Expect = 6.1e-38, P = 6.1e-38
Identities = 85/149 (57%), Positives = 101/149 (67%), Frame = +3
Query: 21 WGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXS 200
WGVNVQ SGSPAN Y A++ PH+R+MGL LP GGHL+HGY T ISA S YF S
Sbjct: 102 WGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPDGGHLSHGYATEN-RKISAVSTYFES 160
Query: 201 LPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRX 380
PY+VN TG IDYD LE+ A+ +RPK+++ G SAY R DYKR REIADKCGA L++
Sbjct: 161 FPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMVDM 220
Query: 381 GAHXRPCWPPKN*-TPFXYCXIVTTTTHKT 467
AH +PF Y IVTTTTHK+
Sbjct: 221 -AHISGLIAAGVIPSPFEYADIVTTTTHKS 249
>gi|6323087 ref|NP_013159.1| serine hydroxymethyltransferase; Shm2p
[Saccharomyces cerevisiae] >gi|1707995|sp|P37291|GLYC_YEAST SERINE
HYDROXYMETHYLTRANSFERASE, CYTOSOLIC (SERINE METHYLASE) (GLYCINE
HYDROXYMETHYLTRANSFERASE) (SHMT) >gi|2117695|pir||S61632 glycine
hydroxymethyltransferase (EC 2.1.2.1), cytosolic - yeast
(Saccharomyces cerevisiae) >gi|1181279|emb|CAA64305.1| (X94607)
glycine hydroxymethyltransferase [Saccharomyces cerevisiae]
>gi|1360402|emb|CAA97588.1| (Z73230) ORF YLR058c [Saccharomyces
cerevisiae]
Length = 469
Frame 3 hits (HSPs): _________________
__________________________________________________
Database sequence: | | | | | 469
0 150 300 450
Plus Strand HSPs:
Score = 416 (146.4 bits), Expect = 6.1e-38, P = 6.1e-38
Identities = 85/149 (57%), Positives = 101/149 (67%), Frame = +3
Query: 21 WGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXS 200
WGVNVQ SGSPAN Y A++ PH+R+MGL LP GGHL+HGY T ISA S YF S
Sbjct: 102 WGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPDGGHLSHGYATEN-RKISAVSTYFES 160
Query: 201 LPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRX 380
PY+VN TG IDYD LE+ A+ +RPK+++ G SAY R DYKR REIADKCGA L++
Sbjct: 161 FPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMVDM 220
Query: 381 GAHXRPCWPPKN*-TPFXYCXIVTTTTHKT 467
AH +PF Y IVTTTTHK+
Sbjct: 221 -AHISGLIAAGVIPSPFEYADIVTTTTHKS 249
>gi|3023886|sp|O13426|GLYC_CANAL SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC
(SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
(SHMII) >gi|2282058|gb|AAB64197.1| (AF009966) serine hydroxymethyl
transferase II [Candida albicans]
Length = 470
Frame 3 hits (HSPs): _________________
Annotated Domains: _________________________________________________
__________________________________________________
Database sequence: | | | | | 470
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 35..63
BLOCKS BL00096B: Serine hydroxymethyltransferas 88..120
BLOCKS BL00096C: Serine hydroxymethyltransferas 121..144
BLOCKS BL00096D: Serine hydroxymethyltransferas 170..210
BLOCKS BL00096E: Serine hydroxymethyltransferas 211..253
BLOCKS BL00096F: Serine hydroxymethyltransferas 283..323
BLOCKS BL00096G: Serine hydroxymethyltransferas 377..414
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 249
PFAM SHMT: Serine hydroxymethyltransferase 18..417
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 18..416
PRODOM PD116679: GLYC(3) GLY2(1) 420..469
PROSITE SHMT: Serine hydroxymethyltransferase py 241..257
__________________
Plus Strand HSPs:
Score = 405 (142.6 bits), Expect = 9.0e-37, P = 9.0e-37
Identities = 83/149 (55%), Positives = 102/149 (68%), Frame = +3
Query: 21 WGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXS 200
WGVNVQ SGSPAN Y A++ PH+R+MGLDLP GGHL+HGY T ISA S YF +
Sbjct: 103 WGVNVQTLSGSPANLQVYQAIMKPHERLMGLDLPHGGHLSHGYQTDS-RKISAVSTYFET 161
Query: 201 LPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRX 380
+PY+V+ TG IDYD LE+ A+ +RPK+++ G SAY R DYKR REIADK GA L++
Sbjct: 162 MPYRVDLETGLIDYDMLEKTAVLYRPKVLVAGTSAYCRLIDYKRMREIADKVGAYLVVDM 221
Query: 381 GAHXRPCWPPKN*-TPFXYCXIVTTTTHKT 467
AH +PF Y IVTTTTHK+
Sbjct: 222 -AHISGLIAAGVIPSPFEYADIVTTTTHKS 250
>gi|6319739 ref|NP_009822.1| Serine hydroxymethyltransferase, mitochondrial;
Shm1p [Saccharomyces cerevisiae] >gi|419894|pir||S29348 glycine
hydroxymethyltransferase (EC 2.1.2.1) precursor, mitochondrial -
yeast (Saccharomyces cerevisiae) >gi|296561|emb|CAA49927.1|
(X70529) ORF YBR1732 [Saccharomyces cerevisiae]
>gi|536692|emb|CAA85226.1| (Z36131) ORF YBR263w [Saccharomyces
cerevisiae]
Length = 565
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | 565
0 150 300 450
Plus Strand HSPs:
Score = 401 (141.2 bits), Expect = 2.4e-36, P = 2.4e-36
Identities = 89/192 (46%), Positives = 114/192 (59%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SG+PAN Y+A++N +R+MGLDLP GGHL+HGY G IS S
Sbjct: 189 DPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISK 248
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF S+PY V+ TTG IDYD L+ A FRPK+I+ G SAY R DY RF+EI+ CGA L
Sbjct: 249 YFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYL 308
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEG-PNPQKRAPEXR 539
+ AH +PF + IVTTTTHK+ F +G + K+ E
Sbjct: 309 MSDM-AHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVTKKGKEIP 367
Query: 540 FLFQEKLTLGVPFP 581
+ ++K+ V FP
Sbjct: 368 YELEKKINFSV-FP 380
>gi|585214|sp|P37292|GLYM_YEAST SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)
(SHMT) >gi|408368|gb|AAA21024.1| (L22528) serine
hydroxymethyltransferase [Saccharomyces cerevisiae]
Length = 490
Frame 3 hits (HSPs): _____________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 490
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 50..78
BLOCKS BL00096B: Serine hydroxymethyltransferas 103..135
BLOCKS BL00096C: Serine hydroxymethyltransferas 136..159
BLOCKS BL00096D: Serine hydroxymethyltransferas 186..226
BLOCKS BL00096E: Serine hydroxymethyltransferas 227..269
BLOCKS BL00096F: Serine hydroxymethyltransferas 298..338
BLOCKS BL00096G: Serine hydroxymethyltransferas 392..429
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 30..470
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 265
PFAM SHMT: Serine hydroxymethyltransferase 33..432
PRODOM PD090152: GLYM_YEAST 1..31
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 33..431
PRODOM PD116687: GLYM_YEAST 433..489
PROSITE SHMT: Serine hydroxymethyltransferase py 257..273
__________________
Plus Strand HSPs:
Score = 401 (141.2 bits), Expect = 2.4e-36, P = 2.4e-36
Identities = 89/192 (46%), Positives = 114/192 (59%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D WGVNVQP SG+PAN Y+A++N +R+MGLDLP GGHL+HGY G IS S
Sbjct: 114 DPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISK 173
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF S+PY V+ TTG IDYD L+ A FRPK+I+ G SAY R DY RF+EI+ CGA L
Sbjct: 174 YFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYL 233
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCX-VHXXGXXFTEG-PNPQKRAPEXR 539
+ AH +PF + IVTTTTHK+ F +G + K+ E
Sbjct: 234 MSDM-AHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVTKKGKEIP 292
Query: 540 FLFQEKLTLGVPFP 581
+ ++K+ V FP
Sbjct: 293 YELEKKINFSV-FP 305
>gi|462185|sp|P34898|GLYC_NEUCR SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC
(SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT)
>gi|539387|pir||A42241 glycine hydroxymethyltransferase (EC
2.1.2.1), cytosolic - Neurospora crassa >gi|7545109|gb|AAA31967.2|
(M81918) serine hydroxymethyltransferase [Neurospora crassa]
Length = 479
Frame 3 hits (HSPs): _____________________
Annotated Domains: ________________________________________________
__________________________________________________
Database sequence: | | | | | 479
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 35..63
BLOCKS BL00096B: Serine hydroxymethyltransferas 88..120
BLOCKS BL00096C: Serine hydroxymethyltransferas 121..144
BLOCKS BL00096D: Serine hydroxymethyltransferas 170..210
BLOCKS BL00096E: Serine hydroxymethyltransferas 211..253
BLOCKS BL00096F: Serine hydroxymethyltransferas 282..322
BLOCKS BL00096G: Serine hydroxymethyltransferas 376..413
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 15..450
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 249
PFAM SHMT: Serine hydroxymethyltransferase 18..416
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 18..415
PRODOM PD116679: GLYC(3) GLY2(1) 417..469
PROSITE SHMT: Serine hydroxymethyltransferase py 241..257
__________________
Plus Strand HSPs:
Score = 395 (139.0 bits), Expect = 1.0e-35, P = 1.0e-35
Identities = 89/191 (46%), Positives = 113/191 (59%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D + WGVNVQ SGSPAN Y A++ H R+MGLDLP GGHL+HGY T ISA S
Sbjct: 99 DPKQWGVNVQCLSGSPANLQVYQAIMPVHGRLMGLDLPHGGHLSHGYQTPQ-RKISAVST 157
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALL 368
YF ++PY+VN TG IDYD LE+ A FRPK+++ G SAY R DY+R R+IAD GA L
Sbjct: 158 YFETMPYRVNIDTGLIDYDTLEKNAQLFRPKVLVAGTSAYCRLIDYERMRKIADSVGAYL 217
Query: 369 LLRXGAHXRPCWPPKN*-TPFXYCXIVTTTTHKTCXVHXXGXXFTEGPNP--QKRAPEXR 539
++ AH + +PF Y +VTTTTHK+ F G K E
Sbjct: 218 VVDM-AHISGLIASEVIPSPFLYADVVTTTTHKSLRGPRGAMIFFRGVRSVDAKTGKETL 276
Query: 540 FLFQEKLTLGVPFP 581
+ ++K+ V FP
Sbjct: 277 YDLEDKINFSV-FP 289
>gi|6319183|gb|AAF07198.1|AF195023_1 (AF195023) SHMT [Plasmodium falciparum]
Length = 442
Frame 3 hits (HSPs): _________________
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | 442
0 150 300
Plus Strand HSPs:
Score = 327 (115.1 bits), Expect = 2.7e-31, Sum P(2) = 2.7e-31
Identities = 73/150 (48%), Positives = 91/150 (60%), Frame = +3
Query: 15 QSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYF 194
+ WGVNVQP SGS AN A A++ +IMG+ L SGGHLTHG++ +S TS F
Sbjct: 90 EEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHLCSGGHLTHGFFDEK-KKVSITSDLF 148
Query: 195 XSLPYKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLL 374
S YK NS GY+D + + AL F+PK+IICG ++YPRD DYK FREI D+ A L
Sbjct: 149 ESKLYKCNSE-GYVDMESVRNLALSFQPKVIICGYTSYPRDIDYKGFREICDEVNAYLFA 207
Query: 375 RXG--AHXRPCWPPKN*TPFXYCXIVTTTTHK 464
+ C N PF Y +VTTTTHK
Sbjct: 208 DISHISSFVACNLLNN--PFTYADVVTTTTHK 237
Score = 42 (14.8 bits), Expect = 2.7e-31, Sum P(2) = 2.7e-31
Identities = 7/10 (70%), Positives = 8/10 (80%), Frame = +1
Query: 571 FPSLQGGPQH 600
FPS QGGP +
Sbjct: 266 FPSFQGGPHN 275
>gi|6919904|sp|Q9WZH9|GLYA_THEMA SERINE HYDROXYMETHYLTRANSFERASE (SERINE
METHYLASE) (SHMT) >gi|7433556|pir||F72341 glycine
hydroxymethyltransferase (EC 2.1.2.1) - Thermotoga maritima (strain
MSB8) >gi|4981245|gb|AAD35802.1|AE001743_4 (AE001743) serine
hydroxymethyltransferase [Thermotoga maritima]
Length = 427
Frame 3 hits (HSPs): ____________________
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | 427
0 150 300
Plus Strand HSPs:
Score = 314 (110.5 bits), Expect = 1.3e-29, Sum P(2) = 1.3e-29
Identities = 72/171 (42%), Positives = 91/171 (53%), Frame = +3
Query: 30 NVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXSLPY 209
NVQP+SGS AN A Y A+ P D IMG+ L GGHLTHG ++ + F +PY
Sbjct: 89 NVQPHSGSQANMAVYLALAQPGDTIMGMSLSHGGHLTHG------APVNFSGKIFKVVPY 142
Query: 210 KVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRXGAH 389
VN T IDYD + AL +PK+I+ GGSAY R D+KRFREIAD+ GA L++
Sbjct: 143 GVNLETETIDYDEVRRLALEHKPKIIVAGGSAYARIIDFKRFREIADEVGAYLMVDMAHF 202
Query: 390 XRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXFTEGPNPQKRAPEXRF 542
+ P Y +VT+TTHKT G T P K + F
Sbjct: 203 AGLVAAGIHPNPLEYAHVVTSTTHKTLRGPRGGLILTNDPEIAKAVDKTIF 253
Score = 39 (13.7 bits), Expect = 1.3e-29, Sum P(2) = 1.3e-29
Identities = 6/8 (75%), Positives = 7/8 (87%), Frame = +1
Query: 571 FPSLQGGP 594
FP +QGGP
Sbjct: 253 FPGIQGGP 260
>gi|7716549|gb|AAF68430.1|AF239165_1 (AF239165) serine hydroxymethyltransferase
[Sus scrofa]
Length = 158
Frame 3 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | | 158
0 50 100 150
Plus Strand HSPs:
Score = 333 (117.2 bits), Expect = 3.8e-29, P = 3.8e-29
Identities = 63/88 (71%), Positives = 70/88 (79%), Frame = +3
Query: 9 DAQSWGVNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSI 188
D Q WGVNVQPYSGSPANFA YTA++ PH RIMGLDLP GGHLTHG+ T ISATSI
Sbjct: 71 DPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTEK-KKISATSI 129
Query: 189 YFXSLPYKVNSTTGYIDYDRLEEKALXF 272
+F S+PYKV+ TGYI+YDRLEE A F
Sbjct: 130 FFESMPYKVDPDTGYINYDRLEENARLF 157
>gi|729608|sp|P39148|GLYA_BACSU SERINE HYDROXYMETHYLTRANSFERASE (SERINE
METHYLASE) (SHMT) >gi|2117693|pir||I40483 glycine
hydroxymethyltransferase (EC 2.1.2.1) glyA - Bacillus subtilis
>gi|556886|emb|CAA86110.1| (Z38002) serine hydroxymethyltransferase
[Bacillus subtilis] >gi|2636215|emb|CAB15707.1| (Z99122) serine
hydroxymethyltransferase [Bacillus subtilis]
>gi|1095424|prf||2108403J Ser hydroxymethyltransferase [Bacillus
subtilis]
Length = 415
Frame 3 hits (HSPs): __________________
Frame 1 hits (HSPs): ___
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 415
0 150 300
__________________
Annotated Domains:
BLOCKS BL00096A: Serine hydroxymethyltransferas 21..49
BLOCKS BL00096B: Serine hydroxymethyltransferas 70..102
BLOCKS BL00096C: Serine hydroxymethyltransferas 103..126
BLOCKS BL00096D: Serine hydroxymethyltransferas 147..187
BLOCKS BL00096E: Serine hydroxymethyltransferas 188..230
BLOCKS BL00096F: Serine hydroxymethyltransferas 245..285
BLOCKS BL00096G: Serine hydroxymethyltransferas 340..377
DOMO DM00789: SERINEHYDROXYMETHYLTRANSFERASEP 1..414
Entrez binding site: PYRIDOXAL PHOSPHATE (BY SI 226
PFAM SHMT: Serine hydroxymethyltransferase 4..380
PRODOM PD001547: GLYA(22) GLYC(7) GLYM(7) 4..379
PRODOM PD163617: GLYA_BACSU 381..414
PROSITE SHMT: Serine hydroxymethyltransferase py 218..234
__________________
Plus Strand HSPs:
Score = 307 (108.1 bits), Expect = 6.8e-29, Sum P(2) = 6.8e-29
Identities = 66/147 (44%), Positives = 89/147 (60%), Frame = +3
Query: 27 VNVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXSLP 206
VNVQP+SG+ AN A Y +L D ++G++L GGHLTHG ++ + + + +
Sbjct: 87 VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHG------SPVNFSGVQYNFVE 140
Query: 207 YKVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRXGA 386
Y V+ T YIDYD + EKAL +PKLI+ G SAYPR D+K+FREIAD+ GA ++ A
Sbjct: 141 YGVDKETQYIDYDDVREKALAHKPKLIVAGASAYPRTIDFKKFREIADEVGAYFMVDM-A 199
Query: 387 HXRPCWPPK-N*TPFXYCXIVTTTTHKT 467
H + P Y VTTTTHKT
Sbjct: 200 HIAGLVAAGLHPNPVPYADFVTTTTHKT 227
Score = 39 (13.7 bits), Expect = 6.8e-29, Sum P(2) = 6.8e-29
Identities = 6/8 (75%), Positives = 7/8 (87%), Frame = +1
Query: 571 FPSLQGGP 594
FP +QGGP
Sbjct: 251 FPGIQGGP 258
Score = 38 (13.4 bits), Expect = 8.7e-29, Sum P(2) = 8.7e-29
Identities = 8/20 (40%), Positives = 12/20 (60%), Frame = +1
Query: 595 QHQFGFSLAKQPFPGL-GXP 651
+ +FG + K FPG+ G P
Sbjct: 239 REEFGKKIDKSIFPGIQGGP 258
>gi|4928761|gb|AAD33721.1| (AF136495) GlyA [Campylobacter lari]
Length = 213
Frame 3 hits (HSPs): _________________________________
Frame 1 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | | | 213
0 50 100 150 200
Plus Strand HSPs:
Score = 301 (106.0 bits), Expect = 2.9e-28, Sum P(2) = 2.9e-28
Identities = 67/146 (45%), Positives = 88/146 (60%), Frame = +3
Query: 30 NVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXSLPY 209
NVQP SGS AN Y A+LNP DRI+G+DL GGHLTHG +S++ + S Y
Sbjct: 40 NVQPNSGSQANQGVYMALLNPGDRILGMDLSHGGHLTHG------SKVSSSGKVYESFFY 93
Query: 210 KVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRXGAH 389
V G I+YD++ E A +PKLI+CG SAYPR D+ +FREIAD+ GA L
Sbjct: 94 GVE-LDGRINYDKVREIAKEIKPKLIVCGASAYPRVIDFAKFREIADEVGAYLFADIAHI 152
Query: 390 XRPCWPPKN*TPFXYCXIVTTTTHKT 467
++ +PF Y +V++TTHKT
Sbjct: 153 AGLVVAGEHPSPFPYAHVVSSTTHKT 178
Score = 39 (13.7 bits), Expect = 2.9e-28, Sum P(2) = 2.9e-28
Identities = 6/8 (75%), Positives = 7/8 (87%), Frame = +1
Query: 571 FPSLQGGP 594
FP +QGGP
Sbjct: 203 FPGIQGGP 210
>gi|6225462|sp|O66776|GLYA_AQUAE SERINE HYDROXYMETHYLTRANSFERASE (SERINE
METHYLASE) (SHMT) >gi|7433536|pir||D70343 glycine
hydroxymethyltransferase (EC 2.1.2.1) - Aquifex aeolicus
>gi|2983131|gb|AAC06734.1| (AE000692) serine hydroxymethyl
transferase [Aquifex aeolicus]
Length = 428
Frame 3 hits (HSPs): __________________
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | 428
0 150 300
Plus Strand HSPs:
Score = 299 (105.3 bits), Expect = 4.7e-28, Sum P(2) = 4.7e-28
Identities = 69/157 (43%), Positives = 88/157 (56%), Frame = +3
Query: 30 NVQPYSGSPANFAAYTAVLNPHDRIMGLDLPSGGHLTHGYYTSGGXXISATSIYFXSLPY 209
NVQP+SGS AN A Y AVLNP D IMG+DL GGHLTHG ++ + + + Y
Sbjct: 88 NVQPHSGSQANMAVYFAVLNPGDTIMGMDLAHGGHLTHG------AKVNFSGKLYNVIHY 141
Query: 210 KVNSTTGYIDYDRLEEKALXFRPKLIICGGSAYPRDWDYKRFREIADKCGALLLLRXGAH 389
VN T IDYD+L + A +PKLI+ G SAYPR +D+ + REIAD+ GAL ++ +
Sbjct: 142 GVNPETELIDYDQLYKLAKEHKPKLIVGGASAYPRVFDWAKMREIADEVGALFMVDMAHY 201
Query: 390 XRPCWPPKN*TPFXYCXIVTTTTHKTCXVHXXGXXFT 500
P Y VT+TTHKT G T
Sbjct: 202 AGLIAGGVYPNPVPYAQFVTSTTHKTLRGPRSGFILT 238
Score = 39 (13.7 bits), Expect = 4.7e-28, Sum P(2) = 4.7e-28
Identities = 6/8 (75%), Positives = 7/8 (87%), Frame = +1
Query: 571 FPSLQGGP 594
FP +QGGP
Sbjct: 251 FPGIQGGP 258
WARNING: HSPs involving 1285 database sequences were not reported due to the
limiting value of parameter B = 50.
Parameters:
filter=none
matrix=BLOSUM62
V=50
B=50
E=10
gi
H=1
sort_by_pvalue
echofilter
ctxfactor=5.92
Query ----- As Used ----- ----- Computed ----
Frame MatID Matrix name Lambda K H Lambda K H
Std. 0 BLOSUM62 0.318 0.135 0.401
+3 0 BLOSUM62 0.318 0.135 0.401 0.329 0.145 0.500
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+2 0 BLOSUM62 0.318 0.135 0.401 0.332 0.149 0.510
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+1 0 BLOSUM62 0.318 0.135 0.401 0.325 0.140 0.483
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-1 0 BLOSUM62 0.318 0.135 0.401 0.351 0.156 0.565
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-2 0 BLOSUM62 0.318 0.135 0.401 0.342 0.152 0.607
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-3 0 BLOSUM62 0.318 0.135 0.401 0.326 0.149 0.487
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
Query
Frame MatID Length Eff.Length E S W T X E2 S2
+3 0 224 209 10. 77 3 12 22 0.099 35
31 0.11 38
+2 0 225 210 10. 77 3 12 22 0.099 35
31 0.11 38
+1 0 225 210 10. 77 3 12 22 0.099 35
31 0.11 38
-1 0 225 213 10. 77 3 12 22 0.10 35
31 0.11 38
-2 0 225 210 10. 77 3 12 22 0.099 35
31 0.11 38
-3 0 224 210 10. 77 3 12 22 0.099 35
31 0.11 38
Statistics:
Database: /usr/local/dot5/sl_home/beauty/seqdb/blast/nr
Title: nr
Release date: unknown
Posted date: 4:06 PM CST Feb 28, 2001
Format: BLAST
# of letters in database: 197,782,623
# of sequences in database: 625,274
# of database sequences satisfying E: 1335
No. of states in DFA: 591 (58 KB)
Total size of DFA: 240 KB (256 KB)
Time to generate neighborhood: 0.01u 0.01s 0.02t Elapsed: 00:00:00
No. of threads or processors used: 6
Search cpu time: 286.73u 1.05s 287.78t Elapsed: 00:00:48
Total cpu time: 286.82u 1.08s 287.90t Elapsed: 00:00:49
Start: Mon Oct 1 21:29:30 2001 End: Mon Oct 1 21:30:19 2001
WARNINGS ISSUED: 2
Annotated Domains Database: March 14, 2000
Release Date: March 14, 2000