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Etorphine - Substance Summary (SID 169418)

A narcotic analgesic morphinan used as a sedative in veterinary practice.


Drug and Chemical Information: (Total:1)         

Pharmacological Action

Analgesics, Opioid - Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.

Hypnotics and Sedatives - Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.

Narcotics - Agents that induce NARCOSIS. This term is considered outdated due to imprecision but continues to be widely used. Originally, agents that ...


  Pharmacological Classification
Chemical Actions and Uses
      Pharmacologic Actions
            Physiological Effects of Drugs
                  Central Nervous System Depressants
                        Hypnotics and Sedatives
                        Narcotics
                  Hypnotics and Sedatives
                  Peripheral Nervous System Agents
                        Sensory System Agents
                              Analgesics
                                    Analgesics, Opioid
                                    Narcotics
            Therapeutic Uses
                  Central Nervous System Agents
                        Analgesics
                              Analgesics, Opioid
                              Narcotics
                        Central Nervous System Depressants
                              Analgesics, Opioid
                              Hypnotics and Sedatives
                              Narcotics
                        Hypnotics and Sedatives


  Chemical Classification
Heterocyclic Compounds
      Alkaloids
            Opiate Alkaloids
                  Morphinans
                        Etorphine
      Heterocyclic Compounds with 4 or More Rings
            Morphinans
                  Etorphine
      Heterocyclic Compounds, Bridged-Ring
            Morphinans
                  Etorphine
Polycyclic Compounds
      Polycyclic Hydrocarbons, Aromatic
            Phenanthrenes
                  Morphinans
                        Etorphine


Safety and Toxicology

EINECS - European Inventory of Existing Commercial Chemical Substances

TOXLINE - Citations to the toxicological literature


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Literature Keyword Mining Tool



Data Source:   

Depositor: ChemIDplus
External ID: 014521961

Depositor-Supplied Synonyms: (Total: 19)
Display: Next 9 | All | Sort:
Etorphine
19-Propylorvinol
7-alpha-Etorphine
M99 Injection
Etorfina [DCIT]
Etorphinum [INN-Latin]
Etorphine [BAN:INN]
DEA No. 9056
EINECS 238-535-9
Etorphine (except hydrochloride salt)


Properties Computed from Structure:
Molecular Weight411.53382 [g/mol]
Molecular FormulaC25H33NO4
XLogP3-AA3.1
H-Bond Donor2
H-Bond Acceptor5
Rotatable Bond Count4
Tautomer Count3
Exact Mass411.240959
MonoIsotopic Mass411.240959
Topological Polar Surface Area62.2
Heavy Atom Count30
Formal Charge0
Complexity772
Isotope Atom Count0
Defined Atom StereoCenter Count3
Undefined Atom StereoCenter Count4
Defined Bond StereoCenter Count0
Undefined Bond StereoCenter Count0
Covalently-Bonded Unit Count1


Descriptors Computed from Structure:
Canonical SMILES: CCCC(C)(C1CC23C=CC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)C)OC)O
Isomeric SMILES: CCCC(C)(C1C[C@@]23C=CC1(C4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)C)OC)O
InChI: InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,
29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,
9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17?,18-,21?,22?,23-,24+,
25?/m1/s1
InChIKey: CAHCBJPUTCKATP-HBDRVVKHSA-N


Substance Information:
SID 169418   
Deposit Date: 2005-08-08
Modify Date: 2006-04-28

CID 26721   
Create Date: 2005-08-08

Related Substances:
Same: 5 Links
Same, Connectivity: 28 Links
Same, Isotopes: 26 Links

Similar Substances: 2883 Links

     
Compound Displayed

2D

3D

Compound ID26721
Molecular Weight411.53382 [g/mol]
Molecular FormulaC25H33NO4
XLogP3-AA3.1
H-Bond Donor2
H-Bond Acceptor5


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