LOCUS NP_666983 306 aa linear ROD 11-FEB-2008
DEFINITION olfactory receptor 1189 [Mus musculus].
ACCESSION NP_666983
VERSION NP_666983.2 GI:110735420
DBSOURCE REFSEQ: accession NM_146772.2
KEYWORDS .
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
Sciurognathi; Muroidea; Muridae; Murinae; Mus.
REFERENCE 1 (residues 1 to 306)
AUTHORS Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
Walker,M., Williams,E.M. and Trask,B.J.
TITLE Odorant receptor expressed sequence tags demonstrate olfactory
expression of over 400 genes, extensive alternate splicing and
unequal expression levels
JOURNAL Genome Biol. 4 (11), R71 (2003)
PUBMED 14611657
REFERENCE 2 (residues 1 to 306)
AUTHORS Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
and Trask,B.J.
TITLE Different evolutionary processes shaped the mouse and human
olfactory receptor gene families
JOURNAL Hum. Mol. Genet. 11 (5), 535-546 (2002)
PUBMED 11875048
REMARK Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE 3 (residues 1 to 306)
AUTHORS Zhang,X. and Firestein,S.
TITLE The olfactory receptor gene superfamily of the mouse
JOURNAL Nat. Neurosci. 5 (2), 124-133 (2002)
PUBMED 11802173
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AL929265.6.
On Jul 26, 2006 this sequence version replaced gi:22129303.
Summary: Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. The nomenclature assigned to the
olfactory receptor genes and proteins for this organism is
independent of other organisms.
Sequence Note: This RefSeq record was created from genomic sequence
data because no single transcript from the same strain was
available for the full length of the gene.
FEATURES Location/Qualifiers
source 1..306
/organism="Mus musculus"
/db_xref="taxon:10090"
/chromosome="2"
Protein 1..306
/product="olfactory receptor 1189"
/note="GA_x6K02T2Q125-50079044-50079964; olfactory
receptor MOR237-2"
/calculated_mol_wt=34488
Region 45..285
/region_name="7tm_1"
/note="7 transmembrane receptor (rhodopsin family);
cl10458"
/db_xref="CDD:127389"
CDS 1..306
/gene="Olfr1189"
/gene_synonym="MOR237-2"
/coded_by="NM_146772.2:1..921"
/db_xref="CCDS:CCDS16341.1"
/db_xref="GeneID:258768"
/db_xref="MGI:3031023"
ORIGIN
1 mmnknnvtef illgvtrdpe lrkilsvlfl imymatvfgn llivvtitrs pslrspmyff
61 llslslmdvt yssviapkli mdslsertiv sfercmtqlf aehffggvgi illivmaydr
121 yvaickplhy vkmmtprvcc lmvggawvgg smhatiqllf myqipfcssn iidhfmcdlf
181 pllklacmdt hilgllviln sgvmcvsifl iliasymvil cslksysseg rrkalstcss
241 hftvvvlffv pciflymrpv vtfpidkama vsftivepml npliytlrnt evkyaiknmc
301 rkqgsh
//