BLASTP 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= SPy_1205 putative anti resistance factor
(407 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,515,104 sequences; 2,222,278,849 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_269344.1| putative antimicrobial resistance factor [... 839 0.0
ref|YP_596753.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 835 0.0
ref|YP_060227.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 833 0.0
ref|NP_607273.1| putative antimicrobial resistance factor [... 833 0.0
ref|YP_602563.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 831 0.0
ref|ZP_00366162.1| COG2348: Uncharacterized protein involve... 831 0.0
ref|YP_280360.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 829 0.0
ref|YP_598643.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 828 0.0
ref|NP_664650.1| putative antimicrobial resistance factor [... 822 0.0
ref|YP_001128437.1| putative peptidoglycan branched peptide... 772 0.0
ref|ZP_02920976.1| hypothetical protein STRINF_01860 [Strep... 547 e-154
ref|ZP_00785643.1| FemAB family protein [Streptococcus agal... 492 e-137
ref|ZP_00782551.1| FemAB family protein [Streptococcus agal... 491 e-137
ref|NP_687540.1| murM protein, putative [Streptococcus agal... 489 e-136
ref|NP_816296.1| FemAB family protein [Enterococcus faecali... 351 7e-95
ref|YP_141518.1| peptidoglycan branched peptide synthesis p... 348 4e-94
ref|YP_820501.1| Peptidoglycan interpeptide bridge formatio... 348 4e-94
ref|YP_139608.1| peptidoglycan branched peptide synthesis p... 347 8e-94
ref|YP_001034838.1| MurM, putative [Streptococcus sanguinis... 337 1e-90
ref|YP_001450900.1| MurM [Streptococcus gordonii str. Chall... 335 4e-90
ref|NP_721140.1| putative peptidoglycan branched peptide sy... 332 4e-89
gb|AAG34920.1|AF281139_1 MurM [Streptococcus pneumoniae] 331 6e-89
ref|ZP_02710235.1| serine/alanine-adding enzyme MurM [Strep... 331 6e-89
ref|ZP_01817314.1| beta-lactam resistance factor [Streptoco... 329 2e-88
ref|ZP_01825757.1| beta-lactam resistance factor [Streptoco... 329 2e-88
ref|NP_345127.1| beta-lactam resistance factor [Streptococc... 329 3e-88
ref|ZP_01820380.1| beta-lactam resistance factor [Streptoco... 328 3e-88
ref|ZP_01829464.1| beta-lactam resistance factor [Streptoco... 328 4e-88
ref|ZP_02714642.1| serine/alanine-adding enzyme MurM [Strep... 328 7e-88
gb|AAY56871.1| serine/alanine-adding enzyme MurM [Streptoco... 327 1e-87
ref|NP_358134.1| Serine/alanine adding enzyme [Streptococcu... 327 1e-87
gb|AAG34921.1|AF281140_1 MurM [Streptococcus pneumoniae] 326 2e-87
emb|CAH57579.1| MurM protein [Streptococcus pneumoniae] 325 3e-87
gb|AAY56867.1| serine/alanine-adding enzyme MurM [Streptoco... 325 3e-87
ref|ZP_01822001.1| beta-lactam resistance factor [Streptoco... 325 3e-87
gb|AAG34918.1|AF281137_1 MurM [Streptococcus pneumoniae] 323 2e-86
ref|ZP_02076864.1| hypothetical protein EUBDOL_00657 [Eubac... 322 2e-86
gb|ABS88698.1| MurM [Streptococcus pneumoniae] 322 4e-86
emb|CAB89537.1| MurM protein [Streptococcus pneumoniae] >gi... 321 6e-86
gb|AAY56874.1| serine/alanine-adding enzyme MurM [Streptoco... 318 6e-85
gb|AAG34919.1|AF281138_1 MurM [Streptococcus pneumoniae] 317 8e-85
gb|AAK07418.1| MurM [Streptococcus pneumoniae] 316 2e-84
ref|YP_001694093.1| MurM [Streptococcus pneumoniae Hungary1... 315 3e-84
gb|AAK07417.1| MurM [Streptococcus pneumoniae] 315 3e-84
emb|CAH57580.1| MurM protein [Streptococcus pneumoniae] 312 3e-83
gb|AAG34917.1|AF281136_1 MurM [Streptococcus pneumoniae] 310 2e-82
ref|YP_602024.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 306 2e-81
ref|YP_596233.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 304 6e-81
ref|YP_598114.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 304 8e-81
ref|NP_268868.1| putative peptidoglycan branched peptide sy... 304 9e-81
ref|YP_279959.1| UDP-N-acetylmuramoylpentapeptide-lysine N(... 303 2e-80
ref|NP_606858.1| putative peptidoglycan branched peptide sy... 302 3e-80
ref|NP_664239.1| putative peptidoglycan branched peptide sy... 301 6e-80
ref|NP_802682.1| putative peptidoglycan branched peptide sy... 301 7e-80
ref|YP_059850.1| Factor essential for expression of methici... 301 7e-80
emb|CAH57578.1| MurM protein [Streptococcus pneumoniae] 301 7e-80
ref|ZP_00366262.1| COG2348: Uncharacterized protein involve... 301 8e-80
emb|CAH57581.1| MurM protein [Streptococcus pneumoniae] 300 1e-79
emb|CAH57577.1| MurM protein [Streptococcus pneumoniae] 300 2e-79
ref|YP_001128893.1| putative peptidoglycan pentaglycine int... 297 1e-78
ref|ZP_00785649.1| beta-lactam resistance factor [Streptoco... 295 4e-78
ref|NP_687539.1| beta-lactam resistance factor [Streptococc... 293 2e-77
ref|YP_329291.1| FemAB family protein [Streptococcus agalac... 292 3e-77
gb|ABX75654.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)... 213 1e-53
ref|YP_001033596.1| putative peptidoglycan branched peptide... 207 2e-51
ref|YP_811932.1| Peptidoglycan interpeptide bridge formatio... 206 3e-51
ref|YP_001692109.1| putative antimicrobial resistance facto... 138 7e-31
ref|YP_001814298.1| Methicillin resistance protein [Exiguob... 130 1e-28
ref|NP_765390.1| FmhB protein [Staphylococcus epidermidis A... 129 5e-28
ref|YP_252705.1| FmhB protein, methicillin resistant factor... 125 7e-27
ref|YP_253446.1| FemB (factor essential for methicillin res... 125 7e-27
ref|ZP_02992217.1| Methicillin resistance protein [Exiguoba... 123 3e-26
gb|AAZ13614.1| MurM [Streptococcus pneumoniae] 122 5e-26
gb|AAZ13613.1| MurM [Streptococcus pneumoniae] 122 6e-26
ref|YP_300741.1| peptidoglycan pentaglycine interpeptide bi... 121 1e-25
ref|YP_494849.1| FmhB protein [Staphylococcus aureus subsp.... 120 1e-25
ref|NP_646997.1| FmhB protein [Staphylococcus aureus subsp.... 120 1e-25
ref|NP_372786.1| FmhB protein [Staphylococcus aureus subsp.... 120 2e-25
ref|YP_187061.1| femX protein [Staphylococcus aureus subsp.... 119 4e-25
ref|YP_417591.1| methicillin resistance factor peptidoglyca... 119 5e-25
ref|YP_041701.1| putative peptidoglycan pentaglycine interp... 117 1e-24
gb|AAY84721.1| MurB9 [Streptococcus pneumoniae] 115 6e-24
ref|YP_188525.1| femB protein [Staphylococcus epidermidis R... 114 2e-23
ref|NP_764613.1| FemB protein [Staphylococcus epidermidis A... 114 2e-23
sp|P95735|FEMB_STAEP Aminoacyltransferase femB >gi|1815620|... 114 2e-23
gb|ACA97855.1| serine/alanine adding enzyme [Streptococcus ... 112 4e-23
gb|ACA97854.1| serine/alanine adding enzyme [Streptococcus ... 112 4e-23
ref|YP_001727511.1| FemAB family protein [Leuconostoc citre... 112 4e-23
ref|ZP_00997195.1| putative peptidoglycan pentaglycine inte... 112 4e-23
gb|AAB53784.1| lysostaphin immunity factor [Staphylococcus ... 112 5e-23
gb|AAD23963.1|AF106851_2 FmhC [Staphylococcus aureus] 111 9e-23
ref|NP_645948.1| FmhC protein [Staphylococcus aureus subsp.... 111 1e-22
ref|NP_371772.1| FmhC protein [Staphylococcus aureus subsp.... 111 1e-22
ref|YP_040635.1| FemAB family protein [Staphylococcus aureu... 110 2e-22
ref|NP_721139.1| putative peptidoglycan branched peptide sy... 110 3e-22
ref|NP_815813.1| FemAB family protein [Enterococcus faecali... 108 6e-22
ref|YP_189557.1| fmhA protein [Staphylococcus epidermidis R... 108 8e-22
ref|YP_301460.1| FemB protein [Staphylococcus saprophyticus... 108 9e-22
ref|NP_371899.1| FemB protein [Staphylococcus aureus subsp.... 108 9e-22
ref|ZP_02761173.1| methicillin resistance factor FemB [Stap... 108 9e-22
ref|NP_563006.1| methicillin resistance factor [Clostridium... 108 1e-21
ref|YP_416707.1| methicillin resistance factor protein [Sta... 108 1e-21
ref|YP_253581.1| FmhC protein [Staphylococcus haemolyticus ... 108 1e-21
ref|NP_646079.1| FemB protein [Staphylococcus aureus subsp.... 107 1e-21
ref|YP_817824.1| Peptidoglycan interpeptide bridge formatio... 107 1e-21
ref|ZP_02951847.1| FemAB family protein [Clostridium perfri... 107 2e-21
ref|ZP_02634418.1| FemAB family protein [Clostridium perfri... 107 2e-21
ref|YP_696770.1| FemAB family protein [Clostridium perfring... 107 2e-21
ref|ZP_02638497.1| FemAB family protein [Clostridium perfri... 106 3e-21
ref|ZP_02631903.1| FemAB family protein [Clostridium perfri... 106 3e-21
ref|YP_431233.1| Methicillin resistance protein [Moorella t... 104 1e-20
ref|NP_765544.1| fmhA protein [Staphylococcus epidermidis A... 103 2e-20
ref|YP_252557.1| fmhA protein / lysostaphin immunity factor... 102 4e-20
ref|YP_300577.1| fmhA protein [Staphylococcus saprophyticus... 102 6e-20
ref|ZP_00121082.1| COG2348: Uncharacterized protein involve... 102 7e-20
ref|NP_695487.1| FemAB-like protein possibly involved in in... 101 1e-19
dbj|BAA21486.1| epr [Staphylococcus capitis] 100 2e-19
ref|ZP_01371899.1| Methicillin resistance protein [Desulfit... 100 3e-19
ref|YP_521176.1| hypothetical protein DSY4943 [Desulfitobac... 99 4e-19
ref|YP_227596.1| lysostaphin endopeptidase resistance prote... 99 4e-19
ref|ZP_02839171.1| Methicillin resistance protein [Arthroba... 99 6e-19
ref|YP_946784.1| putative FemAB family protein [Arthrobacte... 97 2e-18
ref|ZP_02442075.1| hypothetical protein ANACOL_01364 [Anaer... 97 3e-18
ref|NP_695488.1| FemAB-like protein possibly involved in in... 96 3e-18
ref|ZP_00790183.1| beta-lactam resistance factor [Streptoco... 95 7e-18
ref|ZP_00787931.1| beta-lactam resistance factor [Streptoco... 95 8e-18
ref|NP_687538.1| beta-lactam resistance factor [Streptococc... 95 9e-18
ref|YP_041851.1| FemAB family protein [Staphylococcus aureu... 95 1e-17
ref|ZP_00785648.1| beta-lactam resistance factor [Streptoco... 95 1e-17
ref|NP_647150.1| fmhA protein [Staphylococcus aureus subsp.... 95 1e-17
ref|NP_372935.1| fmhA protein [Staphylococcus aureus subsp.... 95 1e-17
ref|YP_329290.1| beta-lactam resistance factor [Streptococc... 95 1e-17
ref|NP_735018.1| hypothetical protein gbs0554 [Streptococcu... 94 1e-17
emb|CAA73372.1| femA [Staphylococcus hominis] 94 1e-17
ref|YP_001679516.1| methicillin resistance protein, putativ... 94 2e-17
ref|YP_141007.1| peptidoglycan branched peptide synthesis p... 93 3e-17
ref|YP_139117.1| peptidoglycan branched peptide synthesis p... 93 4e-17
ref|YP_820103.1| Peptidoglycan interpeptide bridge formatio... 93 4e-17
gb|AAD45259.1|AF145333_1 methicillin resistance protein Fem... 92 9e-17
ref|YP_001694094.1| MurN [Streptococcus pneumoniae Hungary1... 91 2e-16
ref|YP_253447.1| factor essential for methicillin resistanc... 91 2e-16
ref|ZP_00121081.2| COG2348: Uncharacterized protein involve... 91 2e-16
gb|AAC69636.1| factor essential for methicillin resistance ... 90 3e-16
gb|AAC69631.1| factor essential for methicillin resistance ... 90 3e-16
ref|YP_001623976.1| methicillin resistance protein [Renibac... 90 3e-16
gb|AAB52984.1| FemA 89 5e-16
gb|AAC69633.1| factor essential for methicillin resistance ... 89 5e-16
gb|AAD22132.1|U23711_1 FEMA [Staphylococcus haemolyticus] 89 7e-16
gb|AAD33941.1|AF144662_1 factor essential for methicillin r... 89 8e-16
emb|CAJ88363.1| conserved hypothetical protein [Streptomyce... 88 1e-15
ref|NP_688347.1| beta-lactam resistance factor [Streptococc... 88 1e-15
gb|AAC69634.1| factor essential for methicillin resistance ... 88 1e-15
emb|CAB89540.1| MurN protein [Streptococcus pneumoniae] 87 2e-15
ref|ZP_02921095.1| hypothetical protein STRINF_01979 [Strep... 87 2e-15
ref|ZP_00790772.1| beta-lactam resistance factor [Streptoco... 87 2e-15
ref|ZP_02712499.1| alanine-adding enzyme MurN [Streptococcu... 87 2e-15
ref|NP_735856.1| hypothetical protein gbs1419 [Streptococcu... 87 3e-15
gb|AAC69632.1| factor essential for methicillin resistance ... 87 3e-15
ref|NP_764612.1| methicillin resistance factor [Staphylococ... 87 3e-15
ref|YP_602023.1| Factor essential for expression of methici... 86 3e-15
ref|ZP_00366261.1| COG2348: Uncharacterized protein involve... 86 4e-15
ref|NP_268867.1| putative peptidoglycan branched peptide sy... 86 4e-15
ref|YP_279958.1| methicillin resistance expression factor [... 86 4e-15
ref|NP_664238.1| putative peptidoglycan branched peptide sy... 86 4e-15
ref|YP_059849.1| Factor essential for expression of methici... 86 4e-15
ref|YP_596232.1| factor essential for expression of methici... 86 4e-15
ref|ZP_01820381.1| beta-lactam resistance factor [Streptoco... 86 4e-15
ref|NP_606857.1| putative peptidoglycan branched peptide sy... 86 4e-15
emb|CAB89538.1| MurN protein [Streptococcus pneumoniae] 86 5e-15
gb|AAY56883.1| alanine-adding enzyme MurN [Streptococcus pn... 86 6e-15
ref|ZP_01825758.1| beta-lactam resistance factor [Streptoco... 86 6e-15
ref|ZP_01817315.1| beta-lactam resistance factor [Streptoco... 86 6e-15
gb|AAD45258.1|AF145332_1 methicillin resistance protein Fem... 86 6e-15
ref|ZP_01835631.1| beta-lactam resistance factor [Streptoco... 86 6e-15
ref|NP_345128.1| beta-lactam resistance factor [Streptococc... 86 7e-15
ref|YP_329990.1| beta-lactam resistance factor [Streptococc... 85 8e-15
ref|NP_358135.1| Alanine adding enzyme [Streptococcus pneum... 85 1e-14
gb|AAD33942.1|AF144663_1 factor essential for methicillin r... 85 1e-14
ref|YP_519925.1| hypothetical protein DSY3692 [Desulfitobac... 85 1e-14
gb|AAY56880.1| alanine-adding enzyme MurN [Streptococcus pn... 85 1e-14
ref|ZP_01827238.1| beta-lactam resistance factor [Streptoco... 85 1e-14
ref|ZP_00121083.2| COG2348: Uncharacterized protein involve... 85 1e-14
ref|ZP_01544461.1| hypothetical protein, FemAB family [Oeno... 84 2e-14
sp|P95734|FEMA_STAEP Aminoacyltransferase femA 84 2e-14
gb|AAB41947.1| FEMA [Staphylococcus epidermidis] 84 2e-14
ref|ZP_02710236.1| alanine adding enzyme [Streptococcus pne... 83 3e-14
gb|AAY56875.1| alanine-adding enzyme MurN [Streptococcus pn... 82 5e-14
ref|NP_628090.1| hypothetical protein SCO3904 [Streptomyces... 82 5e-14
ref|YP_810465.1| Peptidoglycan interpeptide bridge formatio... 82 6e-14
ref|YP_810968.1| Peptidoglycan interpeptide bridge formatio... 82 6e-14
ref|ZP_02076510.1| hypothetical protein EUBDOL_00299 [Eubac... 82 1e-13
ref|NP_695486.1| FemAB-like protein possibly involved in in... 81 1e-13
ref|NP_624914.1| hypothetical protein SCO0602 [Streptomyces... 81 1e-13
gb|AAC69635.1| factor essential for methicillin resistance ... 81 2e-13
ref|YP_001825188.1| conserved hypothetical protein [Strepto... 80 2e-13
sp|Q2YXZ5|FEMA_STAAB Aminoacyltransferase femA (Factor esse... 80 2e-13
ref|YP_416706.1| factor essential for expression of methici... 80 2e-13
ref|NP_825468.1| hypothetical protein SAV_4291 [Streptomyce... 80 3e-13
ref|NP_371898.1| factor essential for expression of methici... 80 3e-13
ref|NP_646078.1| factor essential for expression of methici... 80 4e-13
pdb|1LRZ|A Chain A, X-Ray Crystal Structure Of Staphylococc... 80 4e-13
ref|YP_186262.1| femA protein [Staphylococcus aureus subsp.... 80 4e-13
ref|YP_001034837.1| hypothetical protein SSA_0861 [Streptoc... 79 6e-13
gb|AAD33940.1|AF144661_1 factor essential for methicillin r... 79 6e-13
gb|AAC46073.1| zoocin A immunity factor [Streptococcus equi... 78 1e-12
ref|YP_301461.1| factor essential for methicillin resistanc... 78 1e-12
ref|YP_040791.1| factor essential for expression of methici... 78 1e-12
gb|ABC75742.1| FemA [Staphylococcus aureus] >gi|85720419|gb... 78 1e-12
gb|ABC75743.1| FemA [Staphylococcus aureus] >gi|85720417|gb... 78 1e-12
gb|ABC75752.1| FemA [Staphylococcus aureus] 78 1e-12
gb|ABC75753.1| FemA [Staphylococcus aureus] 77 2e-12
gb|ABC75741.1| FemA [Staphylococcus aureus] 76 4e-12
ref|ZP_02760942.1| femX protein [Staphylococcus aureus subs... 75 7e-12
pdb|1XF8|A Chain A, Crystal Structure Of Weissella Viridesc... 75 8e-12
ref|ZP_02920977.1| hypothetical protein STRINF_01861 [Strep... 75 8e-12
pdb|1NE9|A Chain A, Crystal Structure Of Weissella Viridesc... 75 1e-11
gb|AAG21689.1| FemX [Weissella viridescens] 75 1e-11
ref|ZP_02963226.1| FemAB-like protein possibly involved in ... 75 1e-11
gb|ABC75747.1| FemA [Staphylococcus aureus] 75 1e-11
ref|YP_755077.1| methicillin resistance protein [Syntrophom... 74 1e-11
gb|ABC75748.1| FemA [Staphylococcus aureus] 74 2e-11
ref|YP_001450901.1| MurN protein [Streptococcus gordonii st... 73 3e-11
pdb|1XE4|A Chain A, Crystal Structure Of Weissella Viridesc... 72 6e-11
ref|YP_057014.1| FemAB family protein [Propionibacterium ac... 68 1e-09
ref|YP_001635938.1| Methicillin resistance protein [Chlorof... 67 3e-09
ref|ZP_00786006.1| beta-lactam resistance factor [Streptoco... 66 6e-09
ref|ZP_01515703.1| Methicillin resistance protein [Chlorofl... 65 1e-08
ref|YP_925855.1| Methicillin resistance protein [Nocardioid... 64 2e-08
ref|YP_001278273.1| Methicillin resistance protein [Roseifl... 64 2e-08
ref|NP_627788.1| hypothetical protein SCO3593 [Streptomyces... 63 3e-08
gb|AAM80555.1| StaO [Streptomyces toyocaensis] 62 8e-08
ref|YP_001542863.1| Methicillin resistance protein [Herpeto... 62 1e-07
ref|YP_138883.1| peptidoglycan branched peptide synthesis p... 61 1e-07
ref|YP_140766.1| peptidoglycan branched peptide synthesis p... 61 2e-07
ref|YP_819882.1| Peptidoglycan interpeptide bridge formatio... 60 4e-07
ref|NP_825052.1| hypothetical protein SAV_3875 [Streptomyce... 59 6e-07
ref|YP_819233.1| Peptidoglycan interpeptide bridge formatio... 52 9e-05
ref|ZP_01544459.1| peptidoglycan branched peptide synthesis... 48 0.001
ref|YP_001728723.1| FemX [Leuconostoc citreum KM20] >gi|169... 48 0.002
ref|YP_810970.1| Peptidoglycan interpeptide bridge formatio... 46 0.005
ref|NP_972343.1| femAB family protein [Treponema denticola ... 42 0.061
ref|YP_004713.1| murM [Thermus thermophilus HB27] >gi|46196... 41 0.14
ref|YP_144369.1| FemA-related protein [Thermus thermophilus... 41 0.15
ref|NP_294786.1| FemA-related protein [Deinococcus radiodur... 40 0.25
ref|YP_001514886.1| hypothetical protein AM1_0520 [Acaryoch... 40 0.31
ref|NP_825051.1| hypothetical protein SAV_3874 [Streptomyce... 39 0.68
ref|ZP_02182777.1| hypothetical protein FBALC1_08118 [Flavo... 39 0.73
ref|ZP_02838884.1| hypothetical protein AchlDRAFT_3494 [Art... 39 0.98
ref|XP_001196888.1| PREDICTED: similar to mollusk-derived g... 38 1.4
gb|ABP51932.1| AcrV [Aeromonas veronii bv. sobria] 37 1.8
gb|AAV67433.1| AcrV [Aeromonas veronii bv. sobria] 37 1.9
gb|AAV67435.1| AcrV [Aeromonas veronii bv. sobria] 37 2.2
ref|ZP_01883996.1| ABC transporter, permease protein, putat... 37 2.8
ref|ZP_02728290.1| hypothetical protein CdifQCD_11195 [Clos... 37 3.0
ref|YP_001431528.1| Methicillin resistance protein [Roseifl... 37 3.1
ref|ZP_02746934.1| hypothetical protein CdifQCD-6_13298 [Cl... 37 3.7
ref|ZP_01805168.1| hypothetical protein CdifQ_04000273 [Clo... 37 3.8
ref|YP_001037287.1| Rubrerythrin [Clostridium thermocellum ... 36 4.6
ref|ZP_01120844.1| hypothetical protein RB2501_13334 [Robig... 35 7.9
ref|ZP_02760943.1| FmhB protein [Staphylococcus aureus subs... 35 8.4
ref|YP_304661.1| hypothetical protein Mbar_A1113 [Methanosa... 35 9.3
>ref|NP_269344.1| putative antimicrobial resistance factor [Streptococcus pyogenes M1
GAS]
ref|YP_282283.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS5005]
gb|AAK34065.1| putative antimicrobial resistance factor [Streptococcus pyogenes M1
GAS]
gb|AAZ51538.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS5005]
Length = 407
Score = 839 bits (2167), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 407/407 (100%), Positives = 407/407 (100%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|YP_596753.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS9429]
ref|YP_600575.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS2096]
gb|ABF32209.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS9429]
gb|ABF36031.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS2096]
Length = 407
Score = 835 bits (2158), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 405/407 (99%), Positives = 406/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|YP_060227.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS10394]
gb|AAT87044.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase;
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10394]
Length = 407
Score = 833 bits (2153), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 404/407 (99%), Positives = 405/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYP VFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|NP_607273.1| putative antimicrobial resistance factor [Streptococcus pyogenes
MGAS8232]
gb|AAL97772.1| putative antimicrobial resistance factor [Streptococcus pyogenes
MGAS8232]
Length = 407
Score = 833 bits (2153), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 404/407 (99%), Positives = 406/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMN+DFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNNDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|YP_602563.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10750]
gb|ABF38019.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10750]
Length = 407
Score = 831 bits (2147), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 403/407 (99%), Positives = 404/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYP VFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMY IRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYTIRKQLKNKH 407
>ref|ZP_00366162.1| COG2348: Uncharacterized protein involved in methicillin resistance
[Streptococcus pyogenes M49 591]
Length = 407
Score = 831 bits (2146), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 403/407 (99%), Positives = 404/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQL LINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYP VFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|YP_280360.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS6180]
gb|AAX72005.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS6180]
Length = 407
Score = 829 bits (2141), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 402/407 (98%), Positives = 403/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQL LINQDITRTQAHQKKRLKKLEDQKAS ERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKLEDQKASFERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYP VFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|YP_598643.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10270]
gb|ABF34099.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10270]
Length = 407
Score = 828 bits (2140), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 402/407 (98%), Positives = 403/407 (99%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLV FTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVVFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQL LINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYP VFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|NP_664650.1| putative antimicrobial resistance factor [Streptococcus pyogenes
MGAS315]
ref|NP_802308.1| putative antimicrobial resistance factor [Streptococcus pyogenes
SSI-1]
gb|AAM79453.1| putative antimicrobial resistance factor [Streptococcus pyogenes
MGAS315]
dbj|BAC64141.1| putative antimicrobial resistance factor [Streptococcus pyogenes
SSI-1]
Length = 407
Score = 822 bits (2123), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 400/407 (98%), Positives = 401/407 (98%)
Query: 1 MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
MTNLTFYAKIGISEEEHD FVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS
Sbjct: 1 MTNLTFYAKIGISEEEHDFFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLS 60
Query: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LLIKLLPLGRSIIYIPRGPVMDYLDRDLV FTMKTLKDYGKTKKALFIKYDPAILLKQYA
Sbjct: 61 LLIKLLPLGRSIIYIPRGPVMDYLDRDLVVFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
Query: 121 LGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
GQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR
Sbjct: 121 PGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
LIKDAKQRGV+TYR SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA
Sbjct: 181 LIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
KVNIPQKLDQYRQQL LINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
Sbjct: 241 KVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYP VFQDAYQDGIIWANMGGVEGSL
Sbjct: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMGGVEGSL 360
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH
Sbjct: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
>ref|YP_001128437.1| putative peptidoglycan branched peptide synthesis protein MurM
[Streptococcus pyogenes str. Manfredo]
emb|CAM30206.1| putative peptidoglycan branched peptide synthesis protein MurM
[Streptococcus pyogenes str. Manfredo]
Length = 405
Score = 772 bits (1993), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 374/378 (98%), Positives = 375/378 (99%)
Query: 30 LQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLV 89
LQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLV
Sbjct: 28 LQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLV 87
Query: 90 AFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLT 149
AFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLT
Sbjct: 88 AFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLT 147
Query: 150 MEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSL 209
MEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGV+TYR SQSELHKFSKIVSL
Sbjct: 148 MEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSL 207
Query: 210 TEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQ 269
TEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQL LINQDIT TQAHQ
Sbjct: 208 TEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLNLINQDITSTQAHQ 267
Query: 270 KKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKF 329
KKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKF
Sbjct: 268 KKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKF 327
Query: 330 YPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPL 389
YPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPL
Sbjct: 328 YPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPL 387
Query: 390 YHIANTMYKIRKQLKNKH 407
YHIANTMYKIRKQLKNKH
Sbjct: 388 YHIANTMYKIRKQLKNKH 405
>ref|ZP_02920976.1| hypothetical protein STRINF_01860 [Streptococcus infantarius subsp.
infantarius ATCC BAA-102]
gb|EDT46855.1| hypothetical protein STRINF_01860 [Streptococcus infantarius subsp.
infantarius ATCC BAA-102]
Length = 405
Score = 547 bits (1410), Expect = e-154, Method: Compositional matrix adjust.
Identities = 254/400 (63%), Positives = 320/400 (80%), Gaps = 1/400 (0%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD+F K Q ++LQ S+WAKIK+ W NERIG YK+++ VAS S+LIK LPL
Sbjct: 5 KIGISAEEHDNFAKASNQTNLLQSSNWAKIKDNWDNERIGFYKDDQLVASASVLIKALPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G +++YIPRGP+MDY D++LVAF + +LK YGKTK ALFIK DPA+LLKQY +G+E +E
Sbjct: 65 GFTMLYIPRGPIMDYSDKELVAFVISSLKKYGKTKHALFIKMDPALLLKQYKIGEEVDEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
L AI NL+ AG WTG T IA+SIQPRFQAN+YTQE++ FPKHT+RL+KDA R
Sbjct: 125 KDTLLAIDNLKAAGCEWTGRTTTIAESIQPRFQANVYTQEDMTTTFPKHTKRLMKDAVHR 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV T R + ++ F+ +V+LTE RK ++LRNE YF+K+M YGD AYLHLAKVN+P++L
Sbjct: 185 GVITTRGTIDDVKAFADVVALTENRKGVALRNEDYFRKMMEIYGDDAYLHLAKVNLPKRL 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILS 308
+Y++QL I +D++ T HQKKRL KL QK S+ +YI EFE F ++YP+E+++AGILS
Sbjct: 245 AEYKEQLAKIEKDLSETAEHQKKRLTKLTQQKNSVTKYIKEFEEFVEKYPDELIIAGILS 304
Query: 309 ISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFK 368
+S+GNVMEMLYAGMND+FKKFYPQY LYP VF+DAY DGIIWANMGGVEG+LDDGLTKFK
Sbjct: 305 VSFGNVMEMLYAGMNDEFKKFYPQYSLYPKVFEDAYADGIIWANMGGVEGTLDDGLTKFK 364
Query: 369 ANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQLKNKH 407
+NF PTIEEFIGEFN+PV+ LY ++N Y IRKQ +N H
Sbjct: 365 SNFNPTIEEFIGEFNIPVNGLLYKLSNLAYNIRKQRRNNH 404
>ref|ZP_00785643.1| FemAB family protein [Streptococcus agalactiae COH1]
gb|EAO75606.1| FemAB family protein [Streptococcus agalactiae COH1]
Length = 411
Score = 492 bits (1267), Expect = e-137, Method: Compositional matrix adjust.
Identities = 226/407 (55%), Positives = 319/407 (78%), Gaps = 3/407 (0%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L ++ +GISE+E+D+F Q ++L S WA++K+ WQNER+G YK+++ VA S+LI
Sbjct: 5 LMYHVTVGISEKEYDAFAIASSQTNLLHSSKWAQVKSNWQNERLGFYKDDQLVAVASILI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
K LPLG +++YIPRGP++DY +++LV F +KTLK++G+ K+A+F K+DPA+LL+QY L +
Sbjct: 65 KSLPLGFTMLYIPRGPIIDYSNKELVGFVLKTLKNFGRKKRAVFAKFDPALLLRQYHLKE 124
Query: 124 EE--EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRL 181
E EE + AI NL+ AG W G T I+++IQPRFQANIYT+ N+E FPKHT+RL
Sbjct: 125 ENVAEEIDESRQAIDNLKSAGAQWIGPTKAISETIQPRFQANIYTKANIEENFPKHTKRL 184
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
IKDAK RGV+ YR + +L KF+ +V+LTE RK ++LRNE YF +LMT YG+ AYL+LAK
Sbjct: 185 IKDAKHRGVQIYRANIDDLPKFATVVALTENRKGVALRNENYFHQLMTIYGEDAYLYLAK 244
Query: 242 VNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV 301
VN+P++L Q+++QL+ I +D++ T +HQK RL +L Q+AS+++YI EF+ F+ +YP+E
Sbjct: 245 VNLPKRLAQFKEQLLQIQRDLSETPSHQKSRLTRLNQQEASVKQYILEFQEFSKKYPDEP 304
Query: 302 VVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD 361
V+AGILSI +GNV+EMLYAGM+D F+KFYPQYLL VF+DA+++GI+ AN+GGVEGSL+
Sbjct: 305 VIAGILSIRFGNVLEMLYAGMDDSFRKFYPQYLLNARVFEDAFKNGIVSANLGGVEGSLN 364
Query: 362 DGLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQLKNKH 407
DGLTKFK+NF P EE+IGEFNL ++P LY +AN Y IRK+ ++ H
Sbjct: 365 DGLTKFKSNFNPRFEEYIGEFNLAINPLLYKLANLAYTIRKKQRHSH 411
>ref|ZP_00782551.1| FemAB family protein [Streptococcus agalactiae H36B]
ref|ZP_00787921.1| FemAB family protein [Streptococcus agalactiae CJB111]
gb|EAO73333.1| FemAB family protein [Streptococcus agalactiae CJB111]
gb|EAO78727.1| FemAB family protein [Streptococcus agalactiae H36B]
Length = 411
Score = 491 bits (1264), Expect = e-137, Method: Compositional matrix adjust.
Identities = 226/407 (55%), Positives = 318/407 (78%), Gaps = 3/407 (0%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L ++ +GISE+E+D+F Q ++L S WA++K+ WQNER+G YK+++ VA S+LI
Sbjct: 5 LMYHVTVGISEKEYDAFAIASSQTNLLHSSKWAQVKSNWQNERLGFYKDDQLVAVASILI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
K LPLG +++YIPRGP+MDY +++LV F +KTLK++G+ K+A+F K+DPA+LL+QY L +
Sbjct: 65 KSLPLGFTMLYIPRGPIMDYSNKELVNFVLKTLKNFGRKKRAVFAKFDPALLLRQYHLKE 124
Query: 124 EE--EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRL 181
E EE + AI NL+ AG W G T I+++IQPRFQANIYT+ N+E FPKHT+RL
Sbjct: 125 ENVAEEIDESRQAIDNLKSAGAQWIGPTKAISETIQPRFQANIYTKANIEENFPKHTKRL 184
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
IKDAK RGV+ YR + +L KF+ +V+LTE RK ++LRNE YF +LMT YG+ AYL+LAK
Sbjct: 185 IKDAKHRGVQIYRANIDDLPKFATVVALTENRKGVALRNENYFHQLMTIYGEDAYLYLAK 244
Query: 242 VNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV 301
VN+P++L Q+++QL+ I +D++ T +HQK RL +L Q+AS+++YI EF+ F+ +YP+E
Sbjct: 245 VNLPKRLAQFKEQLLQIQKDLSETPSHQKSRLTRLNQQEASVKQYILEFQEFSKKYPDEP 304
Query: 302 VVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD 361
V+AGILSI +GNV+EMLYAGM+D F+KFYPQYLL VF+DA+++ I+ AN+GGVEGSL+
Sbjct: 305 VIAGILSIRFGNVLEMLYAGMDDSFRKFYPQYLLNARVFEDAFKNDIVSANLGGVEGSLN 364
Query: 362 DGLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQLKNKH 407
DGLTKFK+NF P EE+IGEFNL ++P LY +AN Y IRK+ ++ H
Sbjct: 365 DGLTKFKSNFNPMFEEYIGEFNLAINPLLYKLANLAYTIRKKQRHSH 411
>ref|NP_687540.1| murM protein, putative [Streptococcus agalactiae 2603V/R]
ref|NP_735020.1| hypothetical protein gbs0556 [Streptococcus agalactiae NEM316]
ref|YP_329292.1| FemAB family protein [Streptococcus agalactiae A909]
ref|ZP_00780378.1| FemAB family protein [Streptococcus agalactiae 18RS21]
ref|ZP_00790181.1| FemAB family protein [Streptococcus agalactiae 515]
gb|AAM99412.1|AE014215_6 murM protein, putative [Streptococcus agalactiae 2603V/R]
emb|CAD46200.1| Unknown [Streptococcus agalactiae NEM316]
gb|ABA45815.1| FemAB family protein [Streptococcus agalactiae A909]
gb|EAO63036.1| FemAB family protein [Streptococcus agalactiae 18RS21]
gb|EAO71074.1| FemAB family protein [Streptococcus agalactiae 515]
Length = 406
Score = 489 bits (1259), Expect = e-136, Method: Compositional matrix adjust.
Identities = 225/405 (55%), Positives = 317/405 (78%), Gaps = 3/405 (0%)
Query: 6 FYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKL 65
++ +GISE+E+D+F Q ++L S WA++K+ WQNER+G YK+++ VA S+LIK
Sbjct: 2 YHVTVGISEKEYDAFAIASSQTNLLHSSKWAQVKSNWQNERLGFYKDDQLVAVASILIKS 61
Query: 66 LPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
LPLG +++YIPRGP+MDY +++LV F +KTLK++G+ K+A+F K+DPA+LL+QY L +E
Sbjct: 62 LPLGFTMLYIPRGPIMDYSNKELVNFVLKTLKNFGRKKRAVFAKFDPALLLRQYHLKEEN 121
Query: 126 --EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
EE + AI NL+ AG W G T I+++IQPRFQANIYT+ N+E FPKHT+RLIK
Sbjct: 122 VAEEIDESRQAIDNLKSAGAQWIGPTKAISETIQPRFQANIYTKANIEENFPKHTKRLIK 181
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
DAK RGV+ YR + +L KF+ +V+LTE RK ++LRNE YF +LMT YG+ AYL+LAKVN
Sbjct: 182 DAKHRGVQIYRANIDDLPKFATVVALTENRKGVALRNENYFHQLMTIYGEDAYLYLAKVN 241
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVV 303
+P++L Q+++QL+ I +D++ T +HQK RL +L Q+AS+++YI EF+ F+ +YP+E V+
Sbjct: 242 LPKRLAQFKEQLLQIQKDLSETPSHQKSRLTRLNQQEASVKQYILEFQEFSKKYPDEPVI 301
Query: 304 AGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDG 363
AGILSI +GNV+EMLYAGM+D F+KFYPQYLL VF+DA+++ I+ AN+GGVEGSL+DG
Sbjct: 302 AGILSIRFGNVLEMLYAGMDDSFRKFYPQYLLNARVFEDAFKNDIVSANLGGVEGSLNDG 361
Query: 364 LTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQLKNKH 407
LTKFK+NF P EE+IGEFNL ++P LY +AN Y IRK+ ++ H
Sbjct: 362 LTKFKSNFNPMFEEYIGEFNLAINPLLYKLANLAYTIRKKQRHSH 406
>ref|NP_816296.1| FemAB family protein [Enterococcus faecalis V583]
gb|AAO82366.1| FemAB family protein [Enterococcus faecalis V583]
Length = 401
Score = 351 bits (900), Expect = 7e-95, Method: Compositional matrix adjust.
Identities = 175/397 (44%), Positives = 265/397 (66%), Gaps = 1/397 (0%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGI E HD+FVK H ++LQ S WAK+K+ W +E +G+Y+++ VAS +LIK LP
Sbjct: 5 KIGIPAEVHDTFVKNHPLCNLLQSSSWAKVKDNWGSEIVGVYEKDTLVASSLVLIKPLPA 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G +++Y PRGPVMDY + LV++ M LK +GK K+ALFIK DPA+ + + LG+E +
Sbjct: 65 GFTMLYTPRGPVMDYTNERLVSYFMAELKKFGKKKRALFIKMDPAVHYQDFHLGEEHQPH 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
A + I+ L+EAG + GLTM++ +IQPRFQANIY ++ E Q K T+++IK A+++
Sbjct: 125 AEATSIIETLKEAGAKYQGLTMDMGATIQPRFQANIYREDFSEEQLSKSTKKMIKTAEKK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV + + +F K++ T +R++ISLRN YF+KL+ Y + +++ LA+VN+ ++L
Sbjct: 185 GVVVQQGHVDFVDEFEKVIQSTMERQHISLRNSDYFKKLLNIYPEDSFIMLAQVNLKERL 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILS 308
D RQ+ +D++ + +Q K+ LE+ ASL R + E E + E V VAG L+
Sbjct: 245 DSTRQRYDKNQKDLSNLKENQVKKRHNLEELDASLTRELKELEENIAEAGEIVTVAGALA 304
Query: 309 ISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFK 368
+++G E+LYAG++D +K++ P Y+ + + Q+ + G NMGG+EGSL+DGL KFK
Sbjct: 305 VTFGPTSEILYAGLDDRYKRYMPTYVTWRDAIQECFNRGCESCNMGGLEGSLNDGLIKFK 364
Query: 369 ANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQLK 404
ANF PTI EFIGEF+LPV+ L+ + YK+RKQ K
Sbjct: 365 ANFNPTINEFIGEFDLPVNKLLFKASEYAYKLRKQKK 401
>ref|YP_141518.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme [Streptococcus thermophilus CNRZ1066]
gb|AAV62703.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme [Streptococcus thermophilus CNRZ1066]
Length = 404
Score = 348 bits (893), Expect = 4e-94, Method: Compositional matrix adjust.
Identities = 175/405 (43%), Positives = 261/405 (64%), Gaps = 5/405 (1%)
Query: 6 FYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKL 65
F KIGIS EHD FV + Q ++LQ S WAKIK+ W N+R+G Y+++K VA S+LI+
Sbjct: 2 FTYKIGISTSEHDRFVIDSPQTNLLQSSSWAKIKDSWGNDRLGFYQDDKLVAVASVLIQP 61
Query: 66 LPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
LPLG S+IYIPRGP+MDY D++L+AF + +LK Y KTK+ALF+K+DP++ + + + QE
Sbjct: 62 LPLGFSMIYIPRGPIMDYQDKELLAFVITSLKKYAKTKRALFVKFDPSLFVTKNLISQEV 121
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDA 185
L+ K++Q GV WTGLT ++A++IQPRFQANIY ++ E Q K T++ I+ A
Sbjct: 122 NINEDTLSIAKDIQALGVEWTGLTEDMAENIQPRFQANIYKEDFTEEQLSKSTKQAIRTA 181
Query: 186 KQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIP 245
+ +G+ L +F+ ++ TE RKNI LR Y++KL+TTY + +Y+ L+ +++P
Sbjct: 182 RNKGISVQFGGTELLDQFADLMKKTEARKNIHLRGIDYYEKLLTTYPESSYITLSTLDLP 241
Query: 246 QKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGF---TDQYPEEVV 302
+L +QL D + +K + K+E+ K +R E D + V
Sbjct: 242 ARLKDLNKQLEKNIADAAKFT--EKTKPGKIENNKQEYKRLSEEIAFLQEKVDAGNKIVP 299
Query: 303 VAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD 362
++G L + +GN E +YAGM++D++++ P L + A++ G W NMGG+E SLD
Sbjct: 300 LSGTLVLEFGNTAENIYAGMDEDYRRYQPAILTWFETANHAFERGAKWQNMGGIENSLDG 359
Query: 363 GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
GL FK+ F P IE+FIGEFNLPVSP Y +AN YK+RK+L++KH
Sbjct: 360 GLYNFKSKFNPRIEQFIGEFNLPVSPFYGLANFAYKVRKKLRSKH 404
>ref|YP_820501.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus
thermophilus LMD-9]
gb|ABJ66305.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus thermophilus LMD-9]
Length = 404
Score = 348 bits (893), Expect = 4e-94, Method: Compositional matrix adjust.
Identities = 175/405 (43%), Positives = 261/405 (64%), Gaps = 5/405 (1%)
Query: 6 FYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKL 65
F KIG+S EHD FV + Q ++LQ S WAKIK+ W N+R+G Y++EK VA S+LI+
Sbjct: 2 FTYKIGLSTSEHDRFVIDSPQTNLLQSSSWAKIKDGWGNDRLGFYRDEKLVAVASVLIQP 61
Query: 66 LPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
LPLG S+IYIPRGP+MDY D++L+AF + +LK Y KTK+ALF+K+DP++ + + + QE
Sbjct: 62 LPLGFSMIYIPRGPIMDYQDKELLAFVITSLKKYAKTKRALFVKFDPSLFVTKNLISQEV 121
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDA 185
L+ K++Q GV WTGLT ++A++IQPRFQANIY ++ E Q K T++ I+ A
Sbjct: 122 NINEDTLSIAKDIQALGVEWTGLTEDMAENIQPRFQANIYKEDFTEEQLSKSTKQAIRTA 181
Query: 186 KQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIP 245
+ +G+ L +F+ ++ TE RKNI LR Y++KL+TTY + +Y+ L+ +++P
Sbjct: 182 RNKGISVQFGGTELLDQFADLMKKTEARKNIHLRGIDYYEKLLTTYPESSYITLSTLDLP 241
Query: 246 QKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGF---TDQYPEEVV 302
+L +QL D + +K + K+E+ K +R E D + V
Sbjct: 242 ARLKDLNKQLEKNIADAAKFT--EKTKPGKIENNKQEYKRLSEEIAFLQEKVDAGNKIVP 299
Query: 303 VAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD 362
++G L + +GN E +YAGM++D++++ P L + A++ G W NMGG+E SLD
Sbjct: 300 LSGTLVLEFGNTAENIYAGMDEDYRRYQPAILTWFETANHAFERGAEWQNMGGIENSLDG 359
Query: 363 GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
GL FK+ F P IE+FIGEFNLPVSP Y +AN YK+RK+L++KH
Sbjct: 360 GLYNFKSKFNPRIEQFIGEFNLPVSPFYGLANFAYKVRKKLRSKH 404
>ref|YP_139608.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme [Streptococcus thermophilus LMG 18311]
gb|AAK18829.1|AF327739_6 MurM [Streptococcus thermophilus]
gb|AAV60793.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme [Streptococcus thermophilus LMG 18311]
Length = 404
Score = 347 bits (890), Expect = 8e-94, Method: Compositional matrix adjust.
Identities = 174/405 (42%), Positives = 261/405 (64%), Gaps = 5/405 (1%)
Query: 6 FYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKL 65
F KIG+S EHD FV + Q ++LQ S WAKIK+ W N+R+G Y+++K VA S+LI+
Sbjct: 2 FTYKIGLSTSEHDRFVIDSPQTNLLQSSSWAKIKDSWGNDRLGFYQDDKLVAVASVLIQP 61
Query: 66 LPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
LPLG S+IYIPRGP+MDY D++L+AF + +LK Y KTK+ALF+K+DP++ + + + QE
Sbjct: 62 LPLGFSMIYIPRGPIMDYQDKELLAFVITSLKKYAKTKRALFVKFDPSLFVTKNLISQEV 121
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDA 185
L+ K++Q GV WTGLT ++A++IQPRFQANIY ++ E Q K T++ I+ A
Sbjct: 122 NINEDTLSIAKDIQALGVEWTGLTEDMAENIQPRFQANIYKEDFTEEQLSKSTKQAIRTA 181
Query: 186 KQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIP 245
+ +G+ L +F+ ++ TE RKNI LR Y++KL+TTY + +Y+ L+ +++P
Sbjct: 182 RNKGISVQFGGTELLDQFADLMKKTEARKNIHLRGIDYYEKLLTTYPESSYITLSTLDLP 241
Query: 246 QKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGF---TDQYPEEVV 302
+L +QL D + +K + K+E+ K +R E D + V
Sbjct: 242 ARLKDLNKQLEKNIADAAKFT--EKTKPGKIENNKQEYKRLSEEIAFLQEKVDAGNKIVP 299
Query: 303 VAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD 362
++G L + +GN E +YAGM++D++++ P L + A++ G W NMGG+E SLD
Sbjct: 300 LSGTLVLEFGNTAENIYAGMDEDYRRYQPAILTWFETANHAFERGAEWQNMGGIENSLDG 359
Query: 363 GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
GL FK+ F P IE+FIGEFNLPVSP Y +AN YK+RK+L++KH
Sbjct: 360 GLYNFKSKFNPRIEQFIGEFNLPVSPFYGLANFAYKVRKKLRSKH 404
>ref|YP_001034838.1| MurM, putative [Streptococcus sanguinis SK36]
gb|ABN44288.1| MurM, putative [Streptococcus sanguinis SK36]
Length = 409
Score = 337 bits (864), Expect = 1e-90, Method: Compositional matrix adjust.
Identities = 164/405 (40%), Positives = 259/405 (63%), Gaps = 1/405 (0%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
+ F KIGIS +EHD FV H Q ++LQ S WA+IK+ W+NER+G YK++ VA+ S+LI
Sbjct: 5 IMFSYKIGISAQEHDDFVTAHPQANLLQSSAWAQIKDNWENERLGFYKDDHLVAAASVLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
K LPLG +++YIPRGP+MDY D++L+ F + +LK + K KKALFIK+DP++ L + +G
Sbjct: 65 KPLPLGMTMLYIPRGPIMDYGDKELLTFVLASLKKFAKEKKALFIKFDPSLFLAESKMGG 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E ++K + I+ LQEAG W G T + ++IQPR QANI+ ++ E K TR+ I+
Sbjct: 125 ELQDKAETIELIQQLQEAGAVWVGRTESLDETIQPRLQANIHKEDFSEELLSKSTRQAIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A+ +G++ L FS ++ TE RKNI LR + Y+QKL+ TY + +Y+ L+ ++
Sbjct: 185 TARNKGIQIQFGGAELLDDFSGLMKKTENRKNIHLRGKDYYQKLLETYPEHSYVTLSTID 244
Query: 244 IPQKLDQYRQQLILINQDITR-TQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVV 302
+ +L+ + QL ++ + T+ + +++ + ++ L+ I + Q V
Sbjct: 245 LKARLEDLQAQLTKTLKEAEKFTEKTKPGKIENNQQEQKRLQEEIDFLQAKISQGAAIVP 304
Query: 303 VAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD 362
++G L + YG E +YAGM+++++++ P + + + A++ G W NMGG+E L
Sbjct: 305 LSGTLVLEYGKTSENIYAGMDEEYRRYQPAIITWYETAKHAFERGADWQNMGGIENDLKG 364
Query: 363 GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
GL FK+ F PTIEEF GEFNLP +PLYH++N Y IRK+L++KH
Sbjct: 365 GLYSFKSKFNPTIEEFAGEFNLPTNPLYHLSNLAYTIRKKLRSKH 409
>ref|YP_001450900.1| MurM [Streptococcus gordonii str. Challis substr. CH1]
gb|ABV09286.1| MurM [Streptococcus gordonii str. Challis substr. CH1]
Length = 409
Score = 335 bits (859), Expect = 4e-90, Method: Compositional matrix adjust.
Identities = 164/407 (40%), Positives = 258/407 (63%), Gaps = 5/407 (1%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
+ F KIGIS +EHD FV H Q ++LQ S WA+IK+ W NER+G YK++ VA+ S+LI
Sbjct: 5 IMFSYKIGISAQEHDDFVTAHPQANLLQSSAWAQIKDNWANERLGFYKDDHLVAAASVLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
K LPLG S++YIPRGP+MDY D++L+ F + +LK + K KKALF+K+DP++ L + +G
Sbjct: 65 KPLPLGMSMLYIPRGPIMDYSDKELLTFVLASLKKFAKEKKALFVKFDPSLFLAESKMGG 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E ++K I+ LQ+AG W G T + ++IQPR QANI+ ++ E K TR+ I+
Sbjct: 125 ELQDKTETAKLIQELQQAGAVWVGRTESLDETIQPRLQANIHKEDFSEELLSKSTRQAIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A+ +G++ L FS ++ TE RKNI LR + Y+QKL+ TY D +Y+ L+ ++
Sbjct: 185 TARNKGIQIQFGGAELLDDFSGLMKKTENRKNIHLRGKDYYQKLLDTYPDNSYITLSSID 244
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVV 303
+ +L+ + QL ++ + +K + K+E+ + +R E + D+ + +
Sbjct: 245 LKARLNDLQAQLTKTLKEAEKFT--EKTKPGKIENNQQEQKRLQEEIDFLQDKISQGATI 302
Query: 304 ---AGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+G L + YG E +YAGM+++++++ P + + + A++ G W NMGG+E L
Sbjct: 303 VPLSGTLVLEYGKTSENIYAGMDEEYRRYQPAIITWYETAKHAFERGADWQNMGGIENDL 362
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
+ GL FK+ F PTIEEF GEFNLP +PLY+++N Y IRK+L++KH
Sbjct: 363 NGGLYSFKSKFNPTIEEFAGEFNLPTNPLYYLSNLAYTIRKKLRSKH 409
>ref|NP_721140.1| putative peptidoglycan branched peptide synthesis protein MurM
[Streptococcus mutans UA159]
gb|AAN58446.1|AE014914_8 putative peptidoglycan branched peptide synthesis protein MurM
[Streptococcus mutans UA159]
Length = 404
Score = 332 bits (850), Expect = 4e-89, Method: Compositional matrix adjust.
Identities = 170/407 (41%), Positives = 251/407 (61%), Gaps = 15/407 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS+EEHD+F+K Q ++LQ S WAK+K++W+NERIG Y++ K VAS S+LI+ LPL
Sbjct: 5 KIGISKEEHDNFIKNSSQTNLLQSSSWAKVKDEWENERIGFYQDSKLVASASILIRPLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++ YIPRGPVM+Y D+DLV F + +LK + K K+ALFIK+DP ILL + + +E
Sbjct: 65 GMTMFYIPRGPVMNYQDKDLVNFVLTSLKKFAKRKRALFIKFDPFILLNHHQIDEEAINN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P A I L+ G W G T ++ ++IQPRFQANIY + E K R+ I+ AK +
Sbjct: 125 PQAQTIIDTLKHLGCEWLGQTSDMGETIQPRFQANIYAEGFSEANLSKKIRQSIRTAKNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK+I LR Y++KL+ Y +++ LA +N+ ++L
Sbjct: 185 GVSIRFGGYELLADFSDLMKKTEDRKSIHLRGIDYYRKLLDNYPQHSFITLASLNLKERL 244
Query: 249 DQYRQQ-------LILINQDITRTQA-HQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ Q L ++ ++ + KK +++L D+ A L+ +++ Q +
Sbjct: 245 TELESQRKKAQNNLAKFGDNVKPSKIDNTKKEIERLSDEIAFLQEHLS-------QGKDT 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
V ++G LS+ +G E +YAGM+D+F+++ + A++ G W NMGG+E L
Sbjct: 298 VPLSGTLSLEFGKTSENVYAGMDDEFRRYQAAIYTWFATANHAFERGSHWQNMGGIENDL 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
GL FK+ F P IEEFIGEFNLPVSPLY +AN Y IRK+ ++KH
Sbjct: 358 SGGLYNFKSKFKPEIEEFIGEFNLPVSPLYKLANIAYTIRKKRRSKH 404
>gb|AAG34920.1|AF281139_1 MurM [Streptococcus pneumoniae]
Length = 406
Score = 331 bits (849), Expect = 6e-89, Method: Compositional matrix adjust.
Identities = 165/402 (41%), Positives = 257/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ W++E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPALEYDQFVKEHELANVLQSSAWEEVKSDWEHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEET-FTESTRTSKVEAQKKEKERLLEELTFLQEYIDAGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
L++ +G LYAGM++DF+++ L + + +++ GI+W N+GGVE +LD GL
Sbjct: 303 TLTLEFGQTSVNLYAGMDEDFRRYKAPILTWYETARYSFERGILWQNLGGVENALDGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
+FKANF PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 RFKANFNPTIEEYLGEFTIPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_02710235.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC1087-00]
gb|EDT91802.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC1087-00]
Length = 406
Score = 331 bits (849), Expect = 6e-89, Method: Compositional matrix adjust.
Identities = 165/402 (41%), Positives = 257/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ ++VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELVNVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R+ K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRISKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_01817314.1| beta-lactam resistance factor [Streptococcus pneumoniae SP3-BS71]
gb|AAY56866.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
gb|EDK75254.1| beta-lactam resistance factor [Streptococcus pneumoniae SP3-BS71]
Length = 406
Score = 329 bits (844), Expect = 2e-88, Method: Compositional matrix adjust.
Identities = 165/402 (41%), Positives = 256/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R+ K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRISKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_01825757.1| beta-lactam resistance factor [Streptococcus pneumoniae SP11-BS70]
ref|ZP_02722360.1| beta-lactam resistance factor [Streptococcus pneumoniae MLV-016]
gb|EDK62975.1| beta-lactam resistance factor [Streptococcus pneumoniae SP11-BS70]
gb|EDT98212.1| beta-lactam resistance factor [Streptococcus pneumoniae MLV-016]
Length = 406
Score = 329 bits (844), Expect = 2e-88, Method: Compositional matrix adjust.
Identities = 166/402 (41%), Positives = 255/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQTIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G+IW N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMIWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|NP_345127.1| beta-lactam resistance factor [Streptococcus pneumoniae TIGR4]
ref|ZP_01408290.1| hypothetical protein SpneT_02001251 [Streptococcus pneumoniae
TIGR4]
emb|CAB89120.1| beta-lactam resistance factor [Streptococcus pneumoniae]
gb|AAK74767.1| beta-lactam resistance factor [Streptococcus pneumoniae TIGR4]
Length = 406
Score = 329 bits (843), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 166/402 (41%), Positives = 255/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G+IW N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMIWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_01820380.1| beta-lactam resistance factor [Streptococcus pneumoniae SP6-BS73]
gb|EDK76554.1| beta-lactam resistance factor [Streptococcus pneumoniae SP6-BS73]
Length = 406
Score = 328 bits (842), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 165/402 (41%), Positives = 255/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_01829464.1| beta-lactam resistance factor [Streptococcus pneumoniae SP18-BS74]
ref|ZP_01832138.1| beta-lactam resistance factor [Streptococcus pneumoniae SP19-BS75]
ref|ZP_01835630.1| beta-lactam resistance factor [Streptococcus pneumoniae SP23-BS72]
ref|ZP_02707799.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC1873-00]
ref|ZP_02712498.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae SP195]
ref|ZP_02716919.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC3059-06]
ref|YP_001835292.1| beta-lactam resistance factor [Streptococcus pneumoniae CGSP14]
gb|AAY56868.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
gb|AAY56869.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
gb|AAY56870.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
gb|AAY56873.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
gb|EDK69625.1| beta-lactam resistance factor [Streptococcus pneumoniae SP18-BS74]
gb|EDK72177.1| beta-lactam resistance factor [Streptococcus pneumoniae SP19-BS75]
gb|EDK81256.1| beta-lactam resistance factor [Streptococcus pneumoniae SP23-BS72]
gb|EDT51848.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC1873-00]
gb|ACB89827.1| beta-lactam resistance factor [Streptococcus pneumoniae CGSP14]
gb|EDT93439.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae SP195]
gb|EDT97476.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC3059-06]
Length = 406
Score = 328 bits (841), Expect = 4e-88, Method: Compositional matrix adjust.
Identities = 165/402 (41%), Positives = 255/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_02714642.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC0288-04]
gb|EDT95501.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae
CDC0288-04]
Length = 406
Score = 328 bits (840), Expect = 7e-88, Method: Compositional matrix adjust.
Identities = 164/402 (40%), Positives = 255/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA +Y + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKLYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>gb|AAY56871.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
Length = 406
Score = 327 bits (838), Expect = 1e-87, Method: Compositional matrix adjust.
Identities = 165/402 (41%), Positives = 254/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W K+K+ W +ER+G+Y+ E +A S+LIK LPL
Sbjct: 5 QIGIPALEYDQFVKEHELANVLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAIFVTFDPSICLSQSLINQEKIEY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYMDAGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
L++ +G LYAGM++DF+++ L + + +++ GI+W N+GGVE +LD GL
Sbjct: 303 TLTLEFGQTSVNLYAGMDEDFRRYKAPILTWYETARYSFERGILWQNLGGVENALDGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
+FKANF PTIEE++GEF +P P+Y + RK L+ KH
Sbjct: 363 RFKANFNPTIEEYLGEFTMPTHPIYPLLRLALDFRKTLRKKH 404
>ref|NP_358134.1| Serine/alanine adding enzyme [Streptococcus pneumoniae R6]
ref|YP_816036.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae D39]
emb|CAB89535.1| MurM protein [Streptococcus pneumoniae]
gb|AAK99344.1| Serine/alanine adding enzyme [Streptococcus pneumoniae R6]
emb|CAC80802.1| MurM protein [Streptococcus pneumoniae]
gb|ABJ53614.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae D39]
Length = 406
Score = 327 bits (838), Expect = 1e-87, Method: Compositional matrix adjust.
Identities = 164/402 (40%), Positives = 254/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+ +F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>gb|AAG34921.1|AF281140_1 MurM [Streptococcus pneumoniae]
Length = 406
Score = 326 bits (836), Expect = 2e-87, Method: Compositional matrix adjust.
Identities = 166/402 (41%), Positives = 252/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ W +ER+G+Y+ E +A S+LIK LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSDWNHERLGVYEGENLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYRDIELLKFVLQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEET-FTESTRTSKVEAQKKEKERLLEELTFLQEYMDAGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
L++ +G LYAGM++DFK++ L + + ++ GI+W N+GGVE +LD GL
Sbjct: 303 TLTLEFGQTSVNLYAGMDEDFKRYKAPILTWYETARYTFERGILWQNLGGVENALDGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
+FKANF PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 RFKANFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>emb|CAH57579.1| MurM protein [Streptococcus pneumoniae]
Length = 407
Score = 325 bits (834), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 164/402 (40%), Positives = 252/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ W++E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 6 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSDWEHEKFGVYREEKLLATASILIRTLPL 65
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 66 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 125
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 126 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 185
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNE Y++KL+ + DKAY+ LA +++ ++
Sbjct: 186 GVEIQFGGTELLESFSFLMKKTEKRKEIHLRNETYYKKLLDNFKDKAYITLATLDVSKRS 245
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 246 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDAGQARVPLAA 303
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
L++ +G LYAGM+DDFK++ L + A++ G++W N+GGVE SL+ GL
Sbjct: 304 TLTLEFGQTSVNLYAGMDDDFKRYNAPILTWYETAHYAFERGMVWQNLGGVENSLNGGLY 363
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 364 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 405
>gb|AAY56867.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
Length = 406
Score = 325 bits (834), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 164/401 (40%), Positives = 254/401 (63%), Gaps = 5/401 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRTLEET-FTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNK 406
FK F PTIEE++GEF +P PLY + RK L+ K
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKK 403
>ref|ZP_01822001.1| beta-lactam resistance factor [Streptococcus pneumoniae SP9-BS68]
gb|EDK79916.1| beta-lactam resistance factor [Streptococcus pneumoniae SP9-BS68]
Length = 406
Score = 325 bits (833), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 164/402 (40%), Positives = 254/402 (63%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF + PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMSTHPLYPLLRLALDFRKTLRKKH 404
>gb|AAG34918.1|AF281137_1 MurM [Streptococcus pneumoniae]
Length = 406
Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 166/402 (41%), Positives = 251/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W K+K+ W +E+ G+Y+E K +A S+LIK LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEKVKSDWNHEKFGVYEEGKLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYIPRGPILDYRDIELLKFVLQSIKSYARSKRAIFVTFDPSICLSQSLINQEKIEY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|ZP_02076864.1| hypothetical protein EUBDOL_00657 [Eubacterium dolichum DSM 3991]
gb|EDP11479.1| hypothetical protein EUBDOL_00657 [Eubacterium dolichum DSM 3991]
Length = 428
Score = 322 bits (826), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 158/396 (39%), Positives = 254/396 (64%), Gaps = 2/396 (0%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
I I ++EHD+FV +H ++LQ + WA +K+ W++E +G+Y +EK VAS S+LIK LPLG
Sbjct: 32 INIPKQEHDAFVSQHALSNLLQSAAWASVKDNWKHEIVGVYDDEKLVASASILIKSLPLG 91
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK- 128
+++YIPRGP+MDY D+DLV + + L+ + K K+ LF+K DP I+ KQ+ L E+ +
Sbjct: 92 FTMMYIPRGPIMDYQDKDLVIYFFQALRKWAKKKRCLFVKVDPGIVYKQFFLDDEQRQAL 151
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
A AI NLQ AG +G + + ++QPRF A++ E+ Q PK +R I AK++
Sbjct: 152 TSAKTAIANLQAAGCIHSGFSTTMDATVQPRFHASVKKCEDYIEQLPKRAKRNIHTAKKK 211
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
++ ++ +F+ ++ LTE+RK I+LR++ YF+KLM YG+ A L +A +++ Q+
Sbjct: 212 KLQIETCGVEKVAEFAHLMKLTEERKQINLRDKEYFRKLMEIYGEHALLQMAYIDLEQEY 271
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILS 308
++ ++ ++ + KK+ LE+Q+ SLER + D + ++V + G LS
Sbjct: 272 NEVIKRYTACLHELEICPENAKKKRFTLEEQQVSLERQKKMLKEELDLHGKKVYICGTLS 331
Query: 309 ISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFK 368
+ +GN E+LYAGM+D FK++ YL + + Q + G W NMGG+EGSLD GLTKFK
Sbjct: 332 VMFGNTAEVLYAGMDDAFKRYMAPYLTWYHTIQACFDRGFEWCNMGGIEGSLDGGLTKFK 391
Query: 369 ANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQL 403
+NF PTI E++GEF+ PV+ L+ + +K+RK++
Sbjct: 392 SNFHPTILEYVGEFDFPVNKLLFKASQIAFKLRKKM 427
>gb|ABS88698.1| MurM [Streptococcus pneumoniae]
Length = 408
Score = 322 bits (824), Expect = 4e-86, Method: Compositional matrix adjust.
Identities = 162/395 (41%), Positives = 250/395 (63%), Gaps = 5/395 (1%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
IGI E+D FVKEH+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPLG
Sbjct: 5 IGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
+ YIPRGP++DY D++L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E P
Sbjct: 65 YKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEFP 124
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRG 189
LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +G
Sbjct: 125 ENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNKG 184
Query: 190 VKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLD 249
++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 LEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRSQ 244
Query: 250 QYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAGI 306
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 ELEEQLA-KNRALEET-FTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAAT 302
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTK 366
LS+ +G +YAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 LSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYH 362
Query: 367 FKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRK 401
FK F PTIEE++GEF +P PLY + RK
Sbjct: 363 FKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRK 397
>emb|CAB89537.1| MurM protein [Streptococcus pneumoniae]
emb|CAB89539.1| MurM protein [Streptococcus pneumoniae]
Length = 406
Score = 321 bits (822), Expect = 6e-86, Method: Compositional matrix adjust.
Identities = 158/402 (39%), Positives = 249/402 (61%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W K+K+ W +ER+G+Y+ E +A S+LIK LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEKVKSDWNHERLGVYEGENLLAVASVLIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY+D++L+ F ++++K Y ++K+A+F+ +DP+I L Q+ + Q++ E
Sbjct: 65 GYKMFYIPRGPILDYMDKELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA ++ L + GV W+G T E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 125 PENLAIVEILGQLGVKWSGQTTEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + + +Y+ L +++ ++L
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYRKLLDNFKEDSYITLTNLDVSKRL 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +Q L + R K+E QK ER + E +G+ + + +A
Sbjct: 245 RELEEQ--LAKNKALEEAFTESTRTSKVEAQKKEKERLVEEIDFLQGYMNMEKSNIPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G LYAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>gb|AAY56874.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
Length = 406
Score = 318 bits (814), Expect = 6e-85, Method: Compositional matrix adjust.
Identities = 156/401 (38%), Positives = 254/401 (63%), Gaps = 3/401 (0%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVK+H+ +VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPTLEYDQFVKDHELGNVLQSSAWEEVKSDWQHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + Y+PRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 65 GYKMFYVPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEAKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNEAY++KL+ + + +Y+ L +++ ++L
Sbjct: 185 GVEIQFGGTELLEPFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDVSKRL 244
Query: 249 DQYRQQLILINQDITR--TQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGI 306
+ +QL N+ + A + ++++ +K LE I +G+ + + +A
Sbjct: 245 RELEEQL-EKNRVVAEKFNDATKPSKVQENIKEKERLEEEIDFLQGYMNMGKSNIPLAAT 303
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTK 366
L++ +G LYAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 304 LTLEFGQTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYH 363
Query: 367 FKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P+ PLY + RK L+ KH
Sbjct: 364 FKEKFNPTIEEYLGEFTMPIHPLYPLLRLALDFRKTLRKKH 404
>gb|AAG34919.1|AF281138_1 MurM [Streptococcus pneumoniae]
Length = 406
Score = 317 bits (813), Expect = 8e-85, Method: Compositional matrix adjust.
Identities = 159/402 (39%), Positives = 252/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVK+H+ +VLQ S W ++K+ W++E+ G+Y+EEK +A+ S+LI+ LPL
Sbjct: 5 QIGIPALEYDQFVKDHELANVLQSSAWEEVKSDWEHEKFGVYREEKLLATASILIRTLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q+ + Q++ E
Sbjct: 65 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKTEY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P L+ ++ L + GV W+G T E+ D+IQPR QA IY + E + K T++ I+ A+ +
Sbjct: 125 PEKLSIVEILGQLGVKWSGRTTEMDDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E QK ER + E + + D V +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLLEELTFLQEYIDAGQARVPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G LYAGM+D FK++ L + + ++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNLYAGMDDAFKRYNAPILTWYETARYTFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>gb|AAK07418.1| MurM [Streptococcus pneumoniae]
Length = 406
Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust.
Identities = 164/402 (40%), Positives = 250/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVK+H+ +VLQ S W K+K+ W +ER+G+Y+E K +A S+LIK LPL
Sbjct: 5 QIGIPALEYDQFVKDHELANVLQSSAWEKVKSDWNHERLGVYEEGKLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q+ + Q++ E
Sbjct: 65 GYKMFYIPRGPILDYRDAELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKTEY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA ++ L + GV W+G T E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 125 PENLALVETLGQLGVKWSGQTAEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ L FS ++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 185 GVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQ---KASLERYITEFEGFTDQYPEEVVVAG 305
+ +QL N+ + T + R K+E Q K LE I +G+ + + +A
Sbjct: 245 QELEEQLA-KNRALEETFT-ESTRTSKVEAQKKEKERLEEEIDFLQGYMNMGKSNIPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +G LYAGM+DDFK++ L + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGTTSVNLYAGMDDDFKRYNAPILTWYETACYAFERGMLWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 HFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>ref|YP_001694093.1| MurM [Streptococcus pneumoniae Hungary19A-6]
gb|AAG34916.1|AF281135_1 MurM [Streptococcus pneumoniae]
gb|AAY56872.1| serine/alanine-adding enzyme MurM [Streptococcus pneumoniae]
gb|ACA37304.1| MurM [Streptococcus pneumoniae Hungary19A-6]
Length = 406
Score = 315 bits (808), Expect = 3e-84, Method: Compositional matrix adjust.
Identities = 154/402 (38%), Positives = 252/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
++GI E+D FVKEH +++LQ S W K+K+ W +ER+G+Y+ E +A S+LIK LPL
Sbjct: 5 QLGIPLSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q+ + Q++ E
Sbjct: 65 GYKMFYIPRGPILDYRDTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA ++ L + GV W+G T+E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 125 PENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + + +Y+ L +++ ++L
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDVSKRL 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLED---QKASLERYITEFEGFTDQYPEEVVVAG 305
+ +Q L + + + R K+++ +K L+ I +G+ + + +A
Sbjct: 245 RELEEQ--LEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +GN LYAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGNTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
+FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 QFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>gb|AAK07417.1| MurM [Streptococcus pneumoniae]
Length = 406
Score = 315 bits (807), Expect = 3e-84, Method: Compositional matrix adjust.
Identities = 154/402 (38%), Positives = 252/402 (62%), Gaps = 5/402 (1%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
++GI E+D FVKEH +++LQ S W K+K+ W +ER+G+Y+ E +A S+LIK LPL
Sbjct: 5 QLGIPVSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q+ + Q++ E
Sbjct: 65 GYKMFYIPRGPILDYRDTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA ++ L + GV W+G T+E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 125 PENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + + +Y+ L +++ ++L
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDVSKRL 244
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLED---QKASLERYITEFEGFTDQYPEEVVVAG 305
+ +Q L + + + R K+++ +K L+ I +G+ + + +A
Sbjct: 245 RELEEQ--LEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPLAA 302
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLT 365
LS+ +GN LYAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 303 TLSLEFGNTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLY 362
Query: 366 KFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
+FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 363 QFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKH 404
>emb|CAH57580.1| MurM protein [Streptococcus pneumoniae]
Length = 407
Score = 312 bits (800), Expect = 3e-83, Method: Compositional matrix adjust.
Identities = 160/401 (39%), Positives = 255/401 (63%), Gaps = 3/401 (0%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W K+K+ W +ER+G+Y+ EK +A S+LIK LP
Sbjct: 6 QIGIPTLEYDQFVKEHELGNVLQSSAWEKVKSDWNHERLGVYEGEKLLAVASILIKSLPF 65
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q+ + Q++ E
Sbjct: 66 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAIFVTFDPSICLSQHLVNQDKREY 125
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA ++ L + GV W+G T E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 126 PENLALVETLGQLGVKWSGRTTEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 185
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++
Sbjct: 186 GLEVQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRS 245
Query: 249 DQYRQQLILINQDI--TRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGI 306
+ +QL N+ + T T++ + +++ + +K LE I +G+ + + +A
Sbjct: 246 QELEEQLA-KNRALEETFTESTRTSKVEAKKKEKERLEEEIDFLQGYMNMGKSNIPLAAT 304
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTK 366
LS+ +G LYAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 305 LSLEFGITSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMLWQNLGGVENSLNGGLYH 364
Query: 367 FKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P PLY + RK L+ KH
Sbjct: 365 FKEKFNPTIEEYLGEFTIPTHPLYPLLRLALDFRKTLRKKH 405
>gb|AAG34917.1|AF281136_1 MurM [Streptococcus pneumoniae]
Length = 406
Score = 310 bits (793), Expect = 2e-82, Method: Compositional matrix adjust.
Identities = 156/401 (38%), Positives = 250/401 (62%), Gaps = 3/401 (0%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
+IGI E+D FVKEH+ +VLQ S W K+K+ W +E+ G+Y+E K +A S+LIK LPL
Sbjct: 5 QIGIPTLEYDQFVKEHELANVLQSSAWEKVKSDWNHEKFGVYEEGKLLAVASILIKSLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L QY + Q++ E
Sbjct: 65 GYKMFYIPRGPILDYRDIELLKFVLQSIKSYARSKRAVFVTFDPSICLSQYLVNQDKIEY 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
P LA ++ L + GV W+G T E+ D+IQPR QA IY + E + K TR+ I+ A+ +
Sbjct: 125 PENLAIVEILGQLGVKWSGRTTEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
G++ L FS+++ TEKRK I LRNE Y++KL+ + + +Y+ L +++ ++L
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNETYYKKLLDNFKEDSYITLTSLDVSKRL 244
Query: 249 DQYRQQLILINQDITR--TQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGI 306
+ +QL N+ + A + ++++ +K LE I +G+ + + +A
Sbjct: 245 RELEEQL-EKNRVVAEKFNDATKPSKIQENIKEKERLEEEIDFLQGYMNMGKSNIPLAAT 303
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTK 366
LS+ +G LYAGM+DDFK++ L + + A++ G++W N+GGVE SL+ GL
Sbjct: 304 LSLEFGITSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMLWQNLGGVENSLNGGLYH 363
Query: 367 FKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNKH 407
FK F PTIEE++GEF +P+ PLY + RK L+ KH
Sbjct: 364 FKEKFNPTIEEYLGEFTMPIHPLYPLLRLALDFRKTLRKKH 404
>ref|YP_602024.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10750]
gb|ABF37480.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10750]
Length = 413
Score = 306 bits (783), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 158/403 (39%), Positives = 245/403 (60%), Gaps = 1/403 (0%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L + KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI
Sbjct: 5 LMYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
+ LPLG ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+
Sbjct: 65 RKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGK 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E +E +AL+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+
Sbjct: 125 ESKENDVALSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A +GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A ++
Sbjct: 185 TATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLD 244
Query: 244 IPQKLDQYRQQL-ILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVV 302
+P++ QQL + + + T + ++ + + A L++ +T +
Sbjct: 245 LPEQKKTLIQQLDKALAEQVRLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTRIP 304
Query: 303 VAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD 362
+A L++ YG E LYAGM+DD++ + L + ++A++ G W N+GGVE D
Sbjct: 305 LAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQDG 364
Query: 363 GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 365 GLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 407
>ref|YP_596233.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS9429]
ref|YP_600119.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS2096]
gb|ABF31689.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS9429]
gb|ABF35575.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS2096]
Length = 413
Score = 304 bits (779), Expect = 6e-81, Method: Compositional matrix adjust.
Identities = 161/410 (39%), Positives = 247/410 (60%), Gaps = 15/410 (3%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L + KIGIS EEHD FV Q +LQ S W K+KN W++ERI Y+ QVA+ + LI
Sbjct: 5 LMYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKNNWKHERISFYENGVQVAAAACLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
+ LPLG ++IYIPRGP+MDY + +L+ F +KTLK GK+K+ALF+K DP++++KQ G+
Sbjct: 65 RKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTVGKSKRALFVKIDPSLVIKQTLEGK 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E +E + L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+
Sbjct: 125 ESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A +GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A ++
Sbjct: 185 TATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLD 244
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYP 298
+P+ Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 245 LPE------QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLA 297
Query: 299 ---EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ +A L++ YG E LYAGM+DD++ + L + ++A++ G W N+GG
Sbjct: 298 TGQTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYKTAKEAFKRGCRWHNLGG 357
Query: 356 VEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
VE D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 VENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 407
>ref|YP_598114.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10270]
gb|ABF33570.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase /
UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-seryltransferase [Streptococcus pyogenes MGAS10270]
Length = 413
Score = 304 bits (778), Expect = 8e-81, Method: Compositional matrix adjust.
Identities = 160/410 (39%), Positives = 248/410 (60%), Gaps = 15/410 (3%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L + KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI
Sbjct: 5 LMYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
+ LPLG ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+
Sbjct: 65 RKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGK 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E +E + L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+
Sbjct: 125 ESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A +GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A ++
Sbjct: 185 TATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLD 244
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYP 298
+P+ Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 245 LPE------QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLA 297
Query: 299 E---EVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ +A L++ YG E LYAGM+DD++ + L + ++A++ G W N+GG
Sbjct: 298 AGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYETAKEAFKRGCRWHNLGG 357
Query: 356 VEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
VE D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 VENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 407
>ref|NP_268868.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes M1
GAS]
ref|YP_281874.1| UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-alanyltransferase/UDP-N-acetylmuramoylpentapeptide-
lysine N(6)-seryltransferase [Streptococcus pyogenes
MGAS5005]
gb|AAK33589.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes M1
GAS]
gb|AAZ51129.1| UDP-N-acetylmuramoylpentapeptide-lysine
N(6)-alanyltransferase/UDP-N-acetylmuramoylpentapeptide-
lysine N(6)-seryltransferase [Streptococcus pyogenes
MGAS5005]
Length = 408
Score = 304 bits (778), Expect = 9e-81, Method: Compositional matrix adjust.
Identities = 160/405 (39%), Positives = 246/405 (60%), Gaps = 15/405 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI+ LPL
Sbjct: 5 KIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALFIK DP++++KQ G+E +E
Sbjct: 65 GFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFIKIDPSLVIKQTLEGKESKEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
+ L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+ A +
Sbjct: 125 DVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A +++P+
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPE-- 242
Query: 249 DQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYP---EE 300
Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 243 ----QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLATGQTR 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+ +A L++ YG E LYAGM+DD++ + L + ++A++ G W N+GGVE
Sbjct: 298 IPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQ 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 DGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 402
>ref|YP_279959.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS6180]
gb|AAX71604.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Streptococcus pyogenes MGAS6180]
Length = 413
Score = 303 bits (775), Expect = 2e-80, Method: Compositional matrix adjust.
Identities = 159/410 (38%), Positives = 248/410 (60%), Gaps = 15/410 (3%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L + KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI
Sbjct: 5 LMYTYKIGISPEEHDQFVLAQPQAGLLQSSKWRKVKDNWKHERISFYENGVQVAAAACLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
+ LPLG ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+
Sbjct: 65 RKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGK 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E +E + L+ I L++ G+ W+G T E+ D+IQPR QANIY ++ PK ++ I+
Sbjct: 125 ESKENDVTLSIIAFLKKLGIEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A +GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A ++
Sbjct: 185 TATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLD 244
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYP 298
+P+ Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 245 LPE------QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLA 297
Query: 299 E---EVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ +A L++ YG E LYAGM+DD++ + L + ++A++ G W N+GG
Sbjct: 298 AGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYETAKEAFKRGCRWHNLGG 357
Query: 356 VEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
VE D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 VENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 407
>ref|NP_606858.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes
MGAS8232]
gb|AAL97357.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes
MGAS8232]
Length = 408
Score = 302 bits (773), Expect = 3e-80, Method: Compositional matrix adjust.
Identities = 159/405 (39%), Positives = 246/405 (60%), Gaps = 15/405 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI+ LPL
Sbjct: 5 KIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++IYIPRGPVMDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+E +E
Sbjct: 65 GFTMIYIPRGPVMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
+ L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+ A +
Sbjct: 125 DVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A +++P+
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLDLPE-- 242
Query: 249 DQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYPE---E 300
Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 243 ----QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTR 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+ +A L++ YG E LYAGM+D+++ + L + ++A++ G W N+GGVE
Sbjct: 298 IPLAATLTLIYGETSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQ 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 DGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 402
>ref|NP_664239.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes
MGAS315]
gb|AAM79042.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes
MGAS315]
Length = 408
Score = 301 bits (771), Expect = 6e-80, Method: Compositional matrix adjust.
Identities = 158/405 (39%), Positives = 246/405 (60%), Gaps = 15/405 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI+ LPL
Sbjct: 5 KIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+E +E
Sbjct: 65 GFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
+ L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+ A +
Sbjct: 125 DVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A +++P+
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPE-- 242
Query: 249 DQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYPE---E 300
Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 243 ----QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTR 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+ +A L++ YG E LYAGM+D+++ + L + ++A++ G W N+GGVE
Sbjct: 298 IPLAATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQ 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 DGGLYHFKARLNPTIEEFTGEFNIPVGLVSSLAILTYNLRKKLRS 402
>ref|NP_802682.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes
SSI-1]
dbj|BAC64515.1| putative peptidoglycan branched peptide synthesis protein,
serine/alanine adding enzyme [Streptococcus pyogenes
SSI-1]
Length = 408
Score = 301 bits (770), Expect = 7e-80, Method: Compositional matrix adjust.
Identities = 158/405 (39%), Positives = 246/405 (60%), Gaps = 15/405 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI+ LPL
Sbjct: 5 KIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+E +E
Sbjct: 65 GFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
+ L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+ A +
Sbjct: 125 DVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A +++P+
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPE-- 242
Query: 249 DQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYPE---E 300
Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 243 ----QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTR 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+ +A L++ YG E LYAGM+D+++ + L + ++A++ G W N+GGVE
Sbjct: 298 IPLAATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQ 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 DGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 402
>ref|YP_059850.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10394]
gb|AAT86667.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10394]
Length = 413
Score = 301 bits (770), Expect = 7e-80, Method: Compositional matrix adjust.
Identities = 159/410 (38%), Positives = 248/410 (60%), Gaps = 15/410 (3%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI 63
L + KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI
Sbjct: 5 LMYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLI 64
Query: 64 KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ 123
+ LPLG ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+
Sbjct: 65 RKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGK 124
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
E +E + L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+
Sbjct: 125 ESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDILPKKAKQSIR 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A +GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A ++
Sbjct: 185 TATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLD 244
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYP 298
+P+ Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 245 LPE------QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLA 297
Query: 299 E---EVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ +A L++ YG E LYAGM+D+++ + L + ++A++ G W N+GG
Sbjct: 298 AGKTRIPLAATLTLIYGETSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGG 357
Query: 356 VEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
VE D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 VENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 407
>emb|CAH57578.1| MurM protein [Streptococcus pneumoniae]
Length = 366
Score = 301 bits (770), Expect = 7e-80, Method: Compositional matrix adjust.
Identities = 150/365 (41%), Positives = 234/365 (64%), Gaps = 5/365 (1%)
Query: 28 SVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRD 87
+VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPLG + YIPRGP++DY D++
Sbjct: 4 NVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKE 63
Query: 88 LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTG 147
L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E P LA I +LQ+ GV W+G
Sbjct: 64 LLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSG 123
Query: 148 LTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIV 207
T E+ D+IQPR QA IY + E + K T++ I+ A+ +G++ L FS+++
Sbjct: 124 KTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQTIRTARNKGLEIQYGGLELLDSFSELM 183
Query: 208 SLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA 267
TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++ + +QL N+ + T
Sbjct: 184 KKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRSQELEEQLA-KNRTLEET-F 241
Query: 268 HQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMND 324
+ R K+E QK ER + E + + D V +A LS+ +G +YAGM+D
Sbjct: 242 TESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVXIYAGMDD 301
Query: 325 DFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNL 384
DFK++ L + + A++ G+IW N+GGVE SL+ GL FK F PTIEE++GEF +
Sbjct: 302 DFKRYNAPILTWYETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTM 361
Query: 385 PVSPL 389
P PL
Sbjct: 362 PTHPL 366
>ref|ZP_00366262.1| COG2348: Uncharacterized protein involved in methicillin resistance
[Streptococcus pyogenes M49 591]
Length = 408
Score = 301 bits (770), Expect = 8e-80, Method: Compositional matrix adjust.
Identities = 158/405 (39%), Positives = 246/405 (60%), Gaps = 15/405 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI+ LPL
Sbjct: 5 KIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+E +E
Sbjct: 65 GFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
+ L+ I L++ GV W+G T E+ D+IQPR QANIY ++ PK ++ I+ A +
Sbjct: 125 DVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A +++P+
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLDLPE-- 242
Query: 249 DQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYPE---E 300
Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 243 ----QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTR 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+ +A L++ YG E LYAGM+D+++ + L + ++A++ G W N+GGVE
Sbjct: 298 IPLAATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQ 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 DGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 402
>emb|CAH57581.1| MurM protein [Streptococcus pneumoniae]
Length = 366
Score = 300 bits (769), Expect = 1e-79, Method: Compositional matrix adjust.
Identities = 149/365 (40%), Positives = 235/365 (64%), Gaps = 5/365 (1%)
Query: 28 SVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRD 87
+VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPLG + YIPRGP++DY D++
Sbjct: 4 NVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKE 63
Query: 88 LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTG 147
L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E P LA I +LQ+ GV W+G
Sbjct: 64 LLNFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSG 123
Query: 148 LTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIV 207
T E+ D+IQPR QA IY + E + K T++ I+ A+ +G++ L FS+++
Sbjct: 124 KTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELM 183
Query: 208 SLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA 267
TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++ + +QL N+ + T
Sbjct: 184 KKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRSQELEEQLA-KNRTLEET-F 241
Query: 268 HQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMND 324
+ R+ K+E QK ER + E + + D V +A LS+ +G +YAGM+D
Sbjct: 242 TESTRISKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDD 301
Query: 325 DFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNL 384
DFK++ L + + A++ G++W N+GGVE SL+ GL FK F PTIEE++GEF +
Sbjct: 302 DFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTM 361
Query: 385 PVSPL 389
P PL
Sbjct: 362 PTHPL 366
>emb|CAH57577.1| MurM protein [Streptococcus pneumoniae]
Length = 366
Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust.
Identities = 149/365 (40%), Positives = 234/365 (64%), Gaps = 5/365 (1%)
Query: 28 SVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRD 87
+VLQ S W ++K+ WQ+E+ G+Y+EEK +A+ S+LI+ LPLG + YIPRGP++DY D++
Sbjct: 4 NVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKE 63
Query: 88 LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTG 147
L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E P LA I +LQ+ GV W+G
Sbjct: 64 LLNFAIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSG 123
Query: 148 LTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIV 207
T E+ D+IQPR QA IY + E + K T++ I+ A+ +G++ L FS+++
Sbjct: 124 KTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELM 183
Query: 208 SLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA 267
TEKRK I LRNEAY++KL+ + DKAY+ LA +++ ++ + +QL N+ + T
Sbjct: 184 KKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSKRSQELEEQLA-KNRTLEET-F 241
Query: 268 HQKKRLKKLEDQKASLERYITE---FEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMND 324
+ R K+E QK ER + E + + D V +A LS+ +G +YAGM+D
Sbjct: 242 TESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDD 301
Query: 325 DFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNL 384
DFK++ L + + A++ G++W N+GGVE SL+ GL FK F PTIEE++GEF +
Sbjct: 302 DFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTM 361
Query: 385 PVSPL 389
P PL
Sbjct: 362 PTHPL 366
>ref|YP_001128893.1| putative peptidoglycan pentaglycine interpeptide biosynthesis
protein [Streptococcus pyogenes str. Manfredo]
emb|CAM30680.1| putative peptidoglycan pentaglycine interpeptide biosynthesis
protein [Streptococcus pyogenes str. Manfredo]
Length = 408
Score = 297 bits (760), Expect = 1e-78, Method: Compositional matrix adjust.
Identities = 157/405 (38%), Positives = 245/405 (60%), Gaps = 15/405 (3%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
KIGIS EEHD FV Q +LQ S W K+K+ W++ERI Y+ QVA+ + LI+ LPL
Sbjct: 5 KIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPL 64
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G ++IYIPRGP+MDY + +L+ F +KTLK +GK+K+ALF+K DP++++KQ G+E +E
Sbjct: 65 GFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKEN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
+ L+ I L++ V W+G T E+ D+IQPR QANIY ++ PK ++ I+ A +
Sbjct: 125 DVTLSIIAFLKKLDVEWSGRTKELEDTIQPRIQANIYAKDFDFDILPKKAKQSIRTATNK 184
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV L FS ++ TE RK I LR ++Y+QKL+ Y ++Y+ +A +++P+
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLDLPE-- 242
Query: 249 DQYRQQLILINQDITRTQAHQ-----KKRLKKLEDQKASLERYITEFEGFTDQYPE---E 300
Q+ +LI Q + + A Q K + K+ + + ++ R + ++Q
Sbjct: 243 ----QKKLLIQQ-LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTR 297
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+ +A L++ YG E LYAGM+D+++ + L + ++A++ G W N+GGVE
Sbjct: 298 IPLAATLTLIYGETSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQ 357
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKN 405
D GL FKA PTIEEF GEFN+PV + +A Y +RK+L++
Sbjct: 358 DGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKLRS 402
>ref|ZP_00785649.1| beta-lactam resistance factor [Streptococcus agalactiae COH1]
gb|EAO75612.1| beta-lactam resistance factor [Streptococcus agalactiae COH1]
Length = 403
Score = 295 bits (755), Expect = 4e-78, Method: Compositional matrix adjust.
Identities = 159/397 (40%), Positives = 245/397 (61%), Gaps = 7/397 (1%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRS 71
I+ EHD FV E Q ++LQ S+W K+K+ W ++ +G + E Q+AS S+LIK LPLG S
Sbjct: 5 ITAVEHDRFVSESNQTNLLQSSNWPKVKDNWGSQLLGFFDGETQIASASILIKSLPLGFS 64
Query: 72 IIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP-- 129
++YIPRGP+MDY + D+V +K LK +GK ++ALFIK DP I LK ++ E P
Sbjct: 65 MLYIPRGPIMDYSNLDIVTKVLKNLKAFGKKQRALFIKCDPLIYLKMVN-AKDFENSPDE 123
Query: 130 -LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
L AI +LQ AG WTG T ++A +IQPRFQAN+Y + + K TR+ I+ +K +
Sbjct: 124 KEGLIAIDHLQRAGADWTGRTTDLAHTIQPRFQANLYANQFGLDKMSKKTRQAIRTSKNK 183
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV S L F++++ TE RK I+LR Y+QKL+ TY + +Y+ +A +++ ++L
Sbjct: 184 GVDIQFGSHELLEDFAELMKKTEDRKGINLRGIDYYQKLLDTYPNNSYITMASLDVAKRL 243
Query: 249 DQYRQQL-ILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVV-VAGI 306
++ ++ I ++ I + +++K++K+ +D L + I + Y ++V +A
Sbjct: 244 EKIEKECQIAQSERIKSLELNREKKVKQHQDTIDRLNKEIDFLKEAQKAYDRDIVPLAAT 303
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTK 366
L++ +GN E +YAGM+D FK + + Q A++ G IW NMGG+E L GL
Sbjct: 304 LTLEFGNTSENIYAGMDDYFKSYSAPIYTWFETAQRAFERGNIWQNMGGIENDLSGGLYH 363
Query: 367 FKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQ 402
FK+ F P IEEFIGEFN+PV+ LY +N +Y +RK+
Sbjct: 364 FKSKFEPIIEEFIGEFNIPVNRLLYKASNYVYALRKK 400
>ref|NP_687539.1| beta-lactam resistance factor [Streptococcus agalactiae 2603V/R]
ref|NP_735019.1| hypothetical protein gbs0555 [Streptococcus agalactiae NEM316]
ref|ZP_00780381.1| MurM [Streptococcus agalactiae 18RS21]
ref|ZP_00782538.1| beta-lactam resistance factor [Streptococcus agalactiae H36B]
ref|ZP_00787939.1| beta-lactam resistance factor [Streptococcus agalactiae CJB111]
ref|ZP_00790194.1| beta-lactam resistance factor [Streptococcus agalactiae 515]
gb|AAM99411.1|AE014215_5 beta-lactam resistance factor [Streptococcus agalactiae 2603V/R]
emb|CAD46199.1| Unknown [Streptococcus agalactiae NEM316]
gb|EAO63039.1| MurM [Streptococcus agalactiae 18RS21]
gb|EAO71087.1| beta-lactam resistance factor [Streptococcus agalactiae 515]
gb|EAO73351.1| beta-lactam resistance factor [Streptococcus agalactiae CJB111]
gb|EAO78714.1| beta-lactam resistance factor [Streptococcus agalactiae H36B]
Length = 403
Score = 293 bits (749), Expect = 2e-77, Method: Compositional matrix adjust.
Identities = 157/399 (39%), Positives = 245/399 (61%), Gaps = 11/399 (2%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRS 71
I+ EHD FV E Q ++LQ S+W K+K+ W ++ +G + E Q+AS S+LIK LPLG S
Sbjct: 5 ITAVEHDRFVSESNQTNLLQSSNWPKVKDNWGSQLLGFFDGETQIASASILIKSLPLGFS 64
Query: 72 IIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP-- 129
++YIPRGP+MDY + D+V +K LK +GK ++ALFIK DP I LK ++ E P
Sbjct: 65 MLYIPRGPIMDYSNLDIVTKVLKDLKAFGKKQRALFIKCDPLIYLKMVN-AKDFENSPDE 123
Query: 130 -LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
L AI +LQ AG WTG T ++A +IQPRFQAN+Y + + K TR+ I+ +K +
Sbjct: 124 KEGLIAIDHLQRAGADWTGRTTDLAHTIQPRFQANLYANQFGLDKMSKKTRQAIRTSKNK 183
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV S L F++++ TE RK I+LR Y+QKL+ TY + +Y+ +A +++ ++L
Sbjct: 184 GVDIQFGSHELLEDFAELMKKTEDRKGINLRGIDYYQKLLDTYPNNSYITMASLDVAKRL 243
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD---QYPEEVV-VA 304
++ ++ + + R ++ + R KK++ + +++R E + + Y +++ +A
Sbjct: 244 EKIEKECQIAQSE--RIKSLELNREKKVKQHQGTIDRLNKEIDFLKEAQKAYDRDIIPLA 301
Query: 305 GILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGL 364
L++ +GN E +YAGM+D FK + + Q A++ G IW NMGG+E L GL
Sbjct: 302 ATLTLEFGNTSENIYAGMDDYFKSYSAPIYTWFETAQRAFERGNIWQNMGGIENDLSGGL 361
Query: 365 TKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQ 402
FK+ F P IEEFIGEFN+PV+ LY +N +Y +RK+
Sbjct: 362 YHFKSKFEPIIEEFIGEFNIPVNRLLYKASNYVYALRKK 400
>ref|YP_329291.1| FemAB family protein [Streptococcus agalactiae A909]
gb|ABA44865.1| FemAB family protein [Streptococcus agalactiae A909]
Length = 403
Score = 292 bits (747), Expect = 3e-77, Method: Compositional matrix adjust.
Identities = 157/399 (39%), Positives = 244/399 (61%), Gaps = 11/399 (2%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRS 71
I+ EHD FV E Q ++LQ S+W K+K+ W ++ +G + E Q+AS S+LIK LPLG S
Sbjct: 5 ITAVEHDRFVSESNQTNLLQSSNWPKVKDNWGSQLLGFFDGETQIASASILIKSLPLGFS 64
Query: 72 IIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP-- 129
++YIPRGP+MDY + D+V +K LK +GK ++ALFIK DP I LK ++ E P
Sbjct: 65 MLYIPRGPIMDYSNLDIVTKVLKDLKAFGKKQRALFIKCDPLIYLKMVN-AKDFENSPDE 123
Query: 130 -LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQR 188
L AI +LQ AG WTG T ++A +IQPRFQAN+Y + + K TR+ I+ +K +
Sbjct: 124 KEGLIAIDHLQRAGADWTGRTTDLAHTIQPRFQANLYANQFGLDKMSKKTRQAIRTSKNK 183
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV S L F++++ TE RK I+LR Y+QKL+ TY + +Y+ +A +++ ++L
Sbjct: 184 GVDIQFGSHELLEDFAELMKKTEDRKGINLRGIDYYQKLLDTYPNNSYITMASLDVAKRL 243
Query: 249 DQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD---QYPEEVV-VA 304
++ ++ + + R ++ + R KK++ +++R E + + Y +++ +A
Sbjct: 244 EKIEKECQIAQSE--RIKSLELNREKKVKQHHGTIDRLNKEIDFLKEAQKAYDRDIIPLA 301
Query: 305 GILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGL 364
L++ +GN E +YAGM+D FK + + Q A++ G IW NMGG+E L GL
Sbjct: 302 ATLTLEFGNTSENIYAGMDDYFKSYSAPIYTWFETAQRAFERGNIWQNMGGIENDLSGGL 361
Query: 365 TKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQ 402
FK+ F P IEEFIGEFN+PV+ LY +N +Y +RK+
Sbjct: 362 YHFKSKFEPIIEEFIGEFNIPVNRLLYKASNYVYALRKK 400
>gb|ABX75654.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Lactococcus lactis subsp. lactis]
Length = 399
Score = 213 bits (543), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 146/415 (35%), Positives = 228/415 (54%), Gaps = 32/415 (7%)
Query: 2 TNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ--VASL 59
T F KI E + F+ + +LQ W K+K++W++E +G ++E VAS
Sbjct: 5 TARKFEFKIMTDLEIVEDFMIKAPLFDILQTPAWGKVKDEWKSEFLGFVEKENSELVASC 64
Query: 60 SLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY 119
+L + LPLG + YIPRG +MDY D +L+ F ++ LK YGK +KALFIK+DP I
Sbjct: 65 LVLTRSLPLGFKMCYIPRGIIMDYSDNELLDFVIQKLKTYGKKEKALFIKFDPLI----- 119
Query: 120 ALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTR 179
E+ A IK L+ GV + G T +I ++IQ RF A I ++EN H+
Sbjct: 120 ------EDSLEADLLIKKLENLGVVYGGKTKKIHETIQFRFDATI-SKENY------HSD 166
Query: 180 RLIKDAKQRGVKT------YRVSQSE-LHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYG 232
+L + K R K ++ Q E + F+ +++LTE RK I+LR++AYF+K++T +
Sbjct: 167 KLSRKLKTRLNKAKKAFPEIKMGQEECIQDFAHLMALTEARKTINLRDKAYFEKILTAFP 226
Query: 233 DKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEG 292
+ + + L N+ + ++ + ++I +++ I +KKRL LE Q + + E
Sbjct: 227 NNSAIVLVYTNVKKLQEEAKDEVIKLSERIKDISNDKKKRL--LEKQLLEKKENMNELSE 284
Query: 293 FTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWAN 352
+ E V AG L I YG LYAGMND+FKK+Y YL + + ++ G + +
Sbjct: 285 IIKKSGELVPSAGNLIIYYGENSYNLYAGMNDNFKKYYVSYLSWDESIKYSFLKGALTHD 344
Query: 353 MGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQLKNK 406
MGGVE GL FK F P+ +E+IGEF++P + +Y + +YK+RK KNK
Sbjct: 345 MGGVEAD-KGGLRSFKKIFNPSFKEYIGEFDIPTNRAIYPLIKRLYKMRKD-KNK 397
>ref|YP_001033596.1| putative peptidoglycan branched peptide synthesis protein
[Lactococcus lactis subsp. cremoris MG1363]
emb|CAL98916.1| putative peptidoglycan branched peptide synthesis protein
[Lactococcus lactis subsp. cremoris MG1363]
Length = 396
Score = 207 bits (526), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 135/407 (33%), Positives = 220/407 (54%), Gaps = 19/407 (4%)
Query: 2 TNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYK--EEKQVASL 59
T+ F K + E+ ++F+ + +LQ W +K++W++E +G + E + +AS
Sbjct: 5 TSREFEFKSIVDLEKVENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETELLASC 64
Query: 60 SLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY 119
+L + LPLG + YIPRG +MDY D +L++F + LK+YGK +KALFIK+DP I
Sbjct: 65 LVLTRSLPLGFKMCYIPRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLI----- 119
Query: 120 ALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTR 179
EE I+ L GV + G T EI ++IQ RF A IY + + K
Sbjct: 120 ------EENSEGKRLIEKLALLGVAYGGRTKEIHETIQFRFDATIYRDDYSYEKLSKKFN 173
Query: 180 RLIKDAKQRGVKTYRVSQSELHK-FSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLH 238
+ AK + ++ Q E + F+++++LTE RK I+LR++AYF+K++ + + +
Sbjct: 174 SRLNKAK-KAFPEIKIGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIV 232
Query: 239 LAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYP 298
+ N+ + LD+ + + + +++ I +KK L LE Q + + + E
Sbjct: 233 IVYTNVKELLDEVKTETLKLSKRIKDISNEKKKVL--LEHQLLEKKDEVNDLEQIIKTSG 290
Query: 299 EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG 358
E V AG L I YG LYAGM+D FKK+Y YL + + ++ G + +MGGVE
Sbjct: 291 EIVPSAGNLIIYYGEKSYNLYAGMDDAFKKYYVSYLSWDESIKYSFLKGALMHDMGGVEA 350
Query: 359 SLDDGLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQLK 404
GL FK F P+ +E++GEF++P + LY + +YK+RK K
Sbjct: 351 D-SGGLRSFKKMFNPSFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK 396
>ref|YP_811932.1| Peptidoglycan interpeptide bridge formation enzyme [Lactococcus
lactis subsp. cremoris SK11]
gb|ABJ73819.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase
[Lactococcus lactis subsp. cremoris SK11]
Length = 396
Score = 206 bits (524), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 133/392 (33%), Positives = 215/392 (54%), Gaps = 21/392 (5%)
Query: 18 DSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYK--EEKQVASLSLLIKLLPLGRSIIYI 75
++F+ + +LQ W +K++W++E +G + E + +AS +L + LPLG + YI
Sbjct: 21 ENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETELLASCLVLTRSLPLGFKMCYI 80
Query: 76 PRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAI 135
PRG +MDY D +L++F + LK+YGK +KALFIK+DP I EE I
Sbjct: 81 PRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLI-----------EENSEGKRLI 129
Query: 136 KNLQEAGVHWTGLTMEIADSIQPRFQANIYTQE-NLEMQFPKHTRRLIKDAKQRGVKTYR 194
+ L GV + G T EI ++IQ RF A IY + + E K RL K ++ +
Sbjct: 130 EKLTLLGVAYGGRTKEIHETIQFRFDATIYKDDYSYEKLSKKFNSRLNKS--KKAFPEIK 187
Query: 195 VSQSELHK-FSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQ 253
+ Q E + F+++++LTE RK I+LR++AYF+K++ + + + + N+ + LD+ +
Sbjct: 188 IGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIVIVYTNVKELLDEVKT 247
Query: 254 QLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGN 313
+ + +++ I +KK L LE Q + + + E E V AG L I YG
Sbjct: 248 ETLKLSKRIKDISNEKKKVL--LEHQLLEKKAEVNDLEQIIKTSGEIVPSAGNLIIYYGE 305
Query: 314 VMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAP 373
LYAGM+D FKK+Y YL + + ++ G + +MGGVE GL FK F P
Sbjct: 306 KSYNLYAGMDDAFKKYYVSYLSWDESIKYSFLKGALMHDMGGVEAD-SGGLRSFKKMFNP 364
Query: 374 TIEEFIGEFNLPVSP-LYHIANTMYKIRKQLK 404
+ +E++GEF++P + LY + +YK+RK K
Sbjct: 365 SFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK 396
>ref|YP_001692109.1| putative antimicrobial resistance factor [Finegoldia magna ATCC
29328]
dbj|BAG08219.1| putative antimicrobial resistance factor [Finegoldia magna ATCC
29328]
Length = 409
Score = 138 bits (348), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 119/410 (29%), Positives = 203/410 (49%), Gaps = 42/410 (10%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV-ASLSLLIKL 65
Y + +S EEHD+FVK H+ + Q W +K W + IG+ K++K + A L LL KL
Sbjct: 3 YEMVTLSAEEHDNFVKNHKYGELNQIYKWQYVKKGWIGKNIGVKKDDKLIGACLILLKKL 62
Query: 66 LPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
L Y P+GPV+DY +++ + T++ LKD+ K K +K+DP + ++ L
Sbjct: 63 PILPYYFAYAPKGPVVDYENKEDLKATIQILKDFCKKNKVFSLKFDPQVSVEIDGL---- 118
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ--ANIYTQENLEMQ-FPKHTRRLI 182
++ +KNL G + GL + + QPR+ +I E M F T+ ++
Sbjct: 119 ------ISYLKNL---GCYHHGLKKGLEYN-QPRYYMITDINKSEKDVMNSFQSRTKSVV 168
Query: 183 KDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYG--DKAYLHLA 240
K + + G++ R +SEL KFSK++ +T KR + R+ YF+ L G D L+L
Sbjct: 169 KKSLKNGLECQRCDKSELPKFSKLMEITSKRDEFNHRSHEYFENLYDVLGPDDDCELYLT 228
Query: 241 KVNIP--------QKLDQYRQQLI----LINQDITRTQAHQ-KKRLKKLEDQKASLERYI 287
K+ IP ++L+Q Q + + +DIT + + K L L++++ + I
Sbjct: 229 KL-IPSLVKKSNEEELNQIDNQELKTKNKLEKDITEDKKNNFLKELDVLDNRRKRCKDLI 287
Query: 288 TEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDG 347
+ + +E+V++G L G LY ++DF+ P YL+ + + A + G
Sbjct: 288 EQMNEYIQNGVDEIVLSGALLTFCGKKSYYLYGASSNDFRDLSPNYLMQWTMMKRAIEKG 347
Query: 348 IIWANMGGVEG-----SLDD---GLTKFKANFAPTIEEFIGEFNLPVSPL 389
+ GGV G +++D GL +FK F + IGEF++ + L
Sbjct: 348 CTTYDFGGVSGYTPEDNVEDHEAGLYEFKKRFGTEMLATIGEFDIVFNKL 397
>ref|YP_001814298.1| Methicillin resistance protein [Exiguobacterium sibiricum 255-15]
gb|ACB61281.1| Methicillin resistance protein [Exiguobacterium sibiricum 255-15]
Length = 419
Score = 130 bits (328), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 117/430 (27%), Positives = 203/430 (47%), Gaps = 46/430 (10%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLI- 63
Y ++ I + + + FVK H + +LQ W +K W +ERI + Q+ ++LL+
Sbjct: 3 YQQLEIEQAQFEQFVKTHPKGDLLQLPAWGSVKAATGWTHERIAVGTASGQLVGVALLLF 62
Query: 64 -KLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG 122
K+ L ++ Y PRG V+DY D+ VA K +KA+ IK DP +
Sbjct: 63 KKVPKLPFTLCYAPRGFVVDYTDQAAVAALRDAAIQVAKKRKAITIKLDPNV-------- 114
Query: 123 QEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIY---TQENLEMQFPKHTR 179
+ E P L +K L G G D QPRF +++ + +F R
Sbjct: 115 -DRTEYPNLLQEMKAL---GFKHNGFGGGF-DYAQPRFTMETSLEGSEKEIFDRFHSKFR 169
Query: 180 RLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKL---MTTYGDKAY 236
++ A+++G+ Y S+ EL F+ ++ T +R S+R YF+ L + GD A
Sbjct: 170 YNVRLAERKGIVCYEASREELKIFANLMVETGERDGFSIRGLDYFENLYDHLRPTGDAA- 228
Query: 237 LHLAKVNIPQKLD-------QYRQQLILINQDITRTQAHQK-----KRLKKLEDQKASLE 284
L L K+++ + L+ Q ++L+ I++ + + +K RL++ Q E
Sbjct: 229 LFLTKLDVVRALENTEAALLQAEKELVKIHRQLEKETVEKKINSLNNRLEQTTAQIEKAE 288
Query: 285 RYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAY 344
+ TE ++P V+++G L G LY ++++++F P +L+ + + A
Sbjct: 289 KSKTELMAIAAKHPNGVILSGGLLTLAGRRSYYLYGASSNEYREFMPNHLMQWTMMRHAK 348
Query: 345 QDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANT--- 395
G + + GGV GS D GL FK+ + + E IGEF+ ++ PLY + T
Sbjct: 349 AHGALSYDFGGVSGSTDPDDHYAGLYAFKSGWGSEMIEKIGEFDYVLNKPLYLLLETGLP 408
Query: 396 -MYKIRKQLK 404
+ KIRK+L+
Sbjct: 409 ILQKIRKKLR 418
>ref|NP_765390.1| FmhB protein [Staphylococcus epidermidis ATCC 12228]
ref|YP_189407.1| femX protein [Staphylococcus epidermidis RP62A]
sp|Q5HLY6|FEMX_STAEQ Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
sp|Q8CNE9|FEMX_STAES Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
gb|AAO05476.1|AE016750_81 FmhB protein [Staphylococcus epidermidis ATCC 12228]
gb|AAW55189.1| femX protein [Staphylococcus epidermidis RP62A]
Length = 416
Score = 129 bits (323), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 121/431 (28%), Positives = 200/431 (46%), Gaps = 50/431 (11%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLS-LLIKL 65
K+ I+ ++HD+FVK H +LQ S WA K W + RI + E Q+ + LL K
Sbjct: 3 KMNITNQQHDAFVKSHPNGDLLQLSKWADTKKLTGWYSRRIAV-GENGQIKGVGQLLFKK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
+P L ++ Y+ RG V DY +++++ + K+ K +K+ IK DP + + + A
Sbjct: 62 IPKLPYTLCYVSRGFVADYNNKEVLEALLSYAKEVAKDEKSYAIKIDPDVEVDKGA---- 117
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANI---YTQENLEMQFPKHTRR 180
A+KNL+E G G ++ D IQPR T + L F + R
Sbjct: 118 --------EALKNLRELGFKHKGFKEGLSKDYIQPRMTMITPIDKTDDELVQSFERRNRS 169
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYL 237
++ A +RG K R ++ L F+ ++ +T +R R+ +YF+ + GD A L
Sbjct: 170 KVRLALKRGTKVERSNREGLKIFANLMKITGERDGFLTRDISYFENIYDALHEDGD-AEL 228
Query: 238 HLAKVNIPQKLDQYRQQL--ILINQDITRTQAHQKKRLKKLED------QKASLERYITE 289
L K+ LD Q L L ++ +++ KK L KL D + L+ +TE
Sbjct: 229 FLVKLEPKPVLDTVNQDLEAQLAEKEKLQSKKQDKKTLNKLNDIDNKIKKTNELKSDLTE 288
Query: 290 FEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
E PE + ++G L + GN LY ++D++ F P + + + + A + G
Sbjct: 289 LE---KSEPEGIYLSGALLMFAGNKSYYLYGASSNDYRDFLPNHHMQFEMMKYAREHGAT 345
Query: 350 WANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTM------- 396
+ GG + D GL FK + + E IGEF+ ++ PLYH+ +
Sbjct: 346 TYDFGGTDNDPDKDSEHYGLWAFKRVWGTYLSEKIGEFDYVLNQPLYHLVEKVKPRLTKA 405
Query: 397 -YKIRKQLKNK 406
KI ++LK K
Sbjct: 406 KIKISRKLKGK 416
>ref|YP_252705.1| FmhB protein, methicillin resistant factor [Staphylococcus
haemolyticus JCSC1435]
sp|Q4L8C6|FEMX_STAHJ Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
dbj|BAE04099.1| FmhB protein, methicillin resistant factor [Staphylococcus
haemolyticus JCSC1435]
Length = 419
Score = 125 bits (313), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 108/408 (26%), Positives = 197/408 (48%), Gaps = 37/408 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK H +LQ + WA+ K W ++R+ + ++ + LL K +
Sbjct: 3 KMNITNQEHDAFVKAHPNGDLLQLTKWAETKRLTGWYSKRVAVGEDGEIKGVGQLLFKKI 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ Y+ RG V DY D+ + ++ K K +KA IK DP + + +
Sbjct: 63 PKLPFTLCYVSRGFVTDYSDKAALEQLLEETKKVAKAEKAYAIKIDPDVEVDK------- 115
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANI---YTQENLEMQFPKHTRRL 181
+ A+KNL G G ++ D IQPR + E + F + R
Sbjct: 116 -----GIDALKNLNALGFKHKGFKEGLSKDYIQPRMTMITPIDKSDEEIFQSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ + +RG K R ++ L F++++ +T +R R+ +YFQ + + GD A L
Sbjct: 171 VRLSLKRGTKVERSNREGLKNFAELMKITGERDGFLTRDLSYFQNIYDSLHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITRTQ-AHQKKRLK----KLEDQKASLERYITEFEGF 293
L K+ LD +L + + T+ Q +++K++K KL D +A +++ I +
Sbjct: 230 LVKLEPKPVLDDIDNELKELESEKTQLQNKYERKQVKKTKNKLNDVEAKIQKSIERKDDM 289
Query: 294 TD---QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
TD ++P + ++G L + G+ LY ++D++ F P + + + + A + G
Sbjct: 290 TDLLAKHPNGIYLSGALLMFAGSKSYYLYGASSNDYRDFLPNHHMQYEMMKFAREHGAKT 349
Query: 351 ANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 YDFGGTDNNPDKDSEHYGLWAFKRVWGTYLSEKIGEFDYVLNQPLYQL 397
>ref|YP_253446.1| FemB (factor essential for methicillin resistance B) protein
[Staphylococcus haemolyticus JCSC1435]
gb|AAD22133.1|U23712_1 FEMB [Staphylococcus haemolyticus]
dbj|BAE04840.1| FemB (factor essential for methicillin resistance B) protein
[Staphylococcus haemolyticus JCSC1435]
Length = 419
Score = 125 bits (313), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 107/383 (27%), Positives = 172/383 (44%), Gaps = 33/383 (8%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+G+ E +V + SL K+ +G + Y RGPVMDY D LV F ++ L+ Y + L
Sbjct: 44 LGVKDESNKVLAASLFSKIPTMGSYVYYSNRGPVMDYSDLGLVDFYLRELEKYLHQHQCL 103
Query: 107 FIKYDPAILLKQYALGQEEEEKPLALAAIKNL-QEAGVHWTGLTMEIADSIQPRFQANIY 165
++K DP + + Y E AI NL + G G T E S Q R+ Y
Sbjct: 104 YVKIDPYWIYQIYDKDINPLEDREKNDAIVNLFKSHGYEHHGFTTEYDTSSQARWMGVSY 163
Query: 166 ----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T +L QF +R I A GVK + + E H F + TE R + +
Sbjct: 164 LKGETPASLRKQFDSQRKRNINKAINYGVKVRFLGRDEFHIFLDLYRETEARTGFVSKTD 223
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKA 281
YF TYGDK + LA ++ LD+Y + L QD + +++ ++ E++
Sbjct: 224 EYFYNFFDTYGDKVLVPLAYID----LDEYIKSL----QDALNDKENRRDQMMAKENKND 275
Query: 282 SLERYITEFEGFTDQYPEEVVVAGIL------------SISYGNVMEMLY--AGMNDDFK 327
R I E + + +E++ A L I + N E+ Y G ++ +
Sbjct: 276 KQLRKIAELDNQIEHDKKELLQASELRQTDGQILNLASGIFFANSYEVNYFSGGSSEKYN 335
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIGEF 382
+ Y+++ ++ ++ G N G+ G S D G+ +FK F IEE IG+F
Sbjct: 336 NYMGPYMMHWHMMNYCFEHGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVYIEELIGDF 395
Query: 383 NLPVSPL-YHIANTMYKIRKQLK 404
P++ + Y + NT+ IRK +K
Sbjct: 396 YKPINKVKYWLFNTLNTIRKNVK 418
>ref|ZP_02992217.1| Methicillin resistance protein [Exiguobacterium sp. AT1b]
gb|EDU19934.1| Methicillin resistance protein [Exiguobacterium sp. AT1b]
Length = 417
Score = 123 bits (308), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 110/422 (26%), Positives = 193/422 (45%), Gaps = 38/422 (9%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLLP 67
I ++E+EHD FVK H + +LQ S W +K N W +ER+ + ++ LL K +P
Sbjct: 6 ITLTEKEHDDFVKTHDRGDLLQLSSWGDVKRQNGWTSERVAVARDGVTSGVALLLFKRVP 65
Query: 68 -LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEE 126
L ++ Y PRG V+DY D + +K KA+ +K DP I + +
Sbjct: 66 KLPYTLCYAPRGFVVDYDDLASLQALVKEATRVATAHKAIVVKIDPNI---------DRD 116
Query: 127 EKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI---YTQENLEMQFPKHTRRLIK 183
E P L + + G G D QPRF +++++ +F R ++
Sbjct: 117 ELPGLLTEMAAI---GFKHKGYGGGF-DYAQPRFTMETDLRPSEKDIFAKFHHKFRYNVR 172
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY-GDKAYLHLA-- 240
A+++G+ V + L F+ ++ +T +R + R YF+ L + A L L
Sbjct: 173 LAEKKGIVCKEVGRDGLKTFADLMKVTGERDGFATRGLDYFENLYDCLQPNDARLFLTTL 232
Query: 241 --KVNIPQK---LDQYRQQLILINQDITRTQAHQKK-----RLKKLEDQKASLERYITEF 290
K+ + Q+ L++ +++L I + + + +K+ R ++ E Q E+ + E
Sbjct: 233 EPKIALEQQQATLEKAKKELAKIERGLEKETIEKKRNSLLNRKEQTEAQIQKAEQALPEL 292
Query: 291 EGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
YP +V++G L G LY +++F++F P +L+ + Q A G
Sbjct: 293 VELDQTYPNGLVLSGGLLTLAGRRSYYLYGASSNEFREFMPNHLMQWTMMQAAKASGAER 352
Query: 351 ANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQLK 404
+ GGV GS D GL FK+ + + E +GEF+L ++ PLY + K L+
Sbjct: 353 YDFGGVSGSTDPDDEYAGLYAFKSGWGSDMIEKVGEFDLVLNRPLYMALEKGLPLLKGLR 412
Query: 405 NK 406
+
Sbjct: 413 KR 414
>gb|AAZ13614.1| MurM [Streptococcus pneumoniae]
Length = 121
Score = 122 bits (306), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 54/121 (44%), Positives = 84/121 (69%)
Query: 63 IKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG 122
I+ LPLG + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q +
Sbjct: 1 IRTLPLGYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAIFVTFDPSICLSQSLIN 60
Query: 123 QEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLI 182
QE+ E P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I
Sbjct: 61 QEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAI 120
Query: 183 K 183
+
Sbjct: 121 R 121
>gb|AAZ13613.1| MurM [Streptococcus pneumoniae]
Length = 121
Score = 122 bits (305), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 54/121 (44%), Positives = 84/121 (69%)
Query: 63 IKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG 122
I+ LPLG + YIPRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q +
Sbjct: 1 IRSLPLGYKMFYIPRGPLLDYRDTELLSFVIQSIKSYARSKRAIFVTFDPSICLSQSLIN 60
Query: 123 QEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLI 182
QE+ E P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I
Sbjct: 61 QEKTEYPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAI 120
Query: 183 K 183
+
Sbjct: 121 R 121
>ref|YP_300741.1| peptidoglycan pentaglycine interpeptide biosynthesis protein
[Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305]
sp|Q49ZI0|FEMX_STAS1 Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
dbj|BAE17796.1| peptidoglycan pentaglycine interpeptide biosynthesis protein
[Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305]
Length = 415
Score = 121 bits (303), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 109/405 (26%), Positives = 185/405 (45%), Gaps = 34/405 (8%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+++ HD+FVK H Q +LQ + WA+ K W + RI + ++++ V LL K +
Sbjct: 3 KMNITDQAHDAFVKAHPQGDLLQLTQWAETKTLTGWYSRRIAVGEDDEIVGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V DY ++ + ++ K +KA IK DP + + + A
Sbjct: 63 PKLPYTLCYISRGFVTDYSNKLALETLLEAAMQIAKEEKAYAIKIDPDVEVDKGA----- 117
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANI---YTQENLEMQFPKHTRRL 181
A+ NL+ G G ++ D IQPR T L F + R
Sbjct: 118 -------DALSNLRALGFKHKGFKEGLSKDYIQPRMTMITPIEKTDVALIQSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R ++ L F+ ++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSNREGLKTFANLMQITGERDGFLTRDISYFENIYDALHPDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITR--TQAHQKKRLKKLEDQK---ASLERYITEFEGF 293
L K+ L+ RQ+L + + + + KK L K+ D A + I E
Sbjct: 230 LVKLEPKPVLEDLRQELHELEDEKAKLADKKQDKKTLNKINDADNKIAKTQELIDEMVTL 289
Query: 294 TDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANM 353
+PE + ++G L + G LY +++++ F P + + + Q A + G +
Sbjct: 290 ESTHPEGIYLSGALLMFAGKKSYYLYGASSNEYRNFLPNHHMQFAMMQYAREHGATSYDF 349
Query: 354 GGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPV-SPLYHI 392
GG + + D GL FK + + E IGEF+ + +PLY I
Sbjct: 350 GGTDNNPDKDSDHYGLWTFKKVWGTYLSEKIGEFDYVLNAPLYQI 394
>ref|YP_494849.1| FmhB protein [Staphylococcus aureus subsp. aureus USA300]
ref|YP_500991.1| FmhB protein, putative [Staphylococcus aureus subsp. aureus NCTC
8325]
ref|YP_001333197.1| peptidoglycan pentaglycine interpeptide biosynthesis protein
[Staphylococcus aureus subsp. aureus str. Newman]
ref|YP_001576116.1| peptidoglycan pentaglycine interpeptide biosynthesis protein FmhB
[Staphylococcus aureus subsp. aureus USA300_TCH1516]
sp|Q2FEM9|FEMX_STAA3 Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
sp|Q2FVZ4|FEMX_STAA8 Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
gb|ABD22463.1| FmhB protein [Staphylococcus aureus subsp. aureus USA300_FPR3757]
gb|ABD31542.1| FmhB protein, putative [Staphylococcus aureus subsp. aureus NCTC
8325]
dbj|BAF68435.1| peptidoglycan pentaglycine interpeptide biosynthesis protein
[Staphylococcus aureus subsp. aureus str. Newman]
gb|ABX30237.1| peptidoglycan pentaglycine interpeptide biosynthesis protein FmhB
[Staphylococcus aureus subsp. aureus USA300_TCH1516]
Length = 421
Score = 120 bits (302), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 106/410 (25%), Positives = 190/410 (46%), Gaps = 39/410 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK H +LQ + WA+ K W RI + ++ + LL K +
Sbjct: 3 KMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V+DY +++ + + + K+ K +KA IK DP +
Sbjct: 63 PKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDV----------- 111
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANIYTQEN---LEMQFPKHTRRL 181
E A++NL+ G G ++ D IQPR +N L F + R
Sbjct: 112 -EVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R + L F++++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITRTQAHQK---KRLKKLEDQKASLERYIT------- 288
L K++ + + + Q+L ++ +I + Q K K+ KK ++ + I
Sbjct: 230 LVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKR 289
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ E ++PE + ++G L + G+ LY +++F+ F P + + + + A + G
Sbjct: 290 DLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGA 349
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 TTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQL 399
>ref|NP_646997.1| FmhB protein [Staphylococcus aureus subsp. aureus MW2]
ref|YP_044264.1| putative peptidoglycan pentaglycine interpeptide biosynthesis
protein [Staphylococcus aureus subsp. aureus MSSA476]
sp|Q6G760|FEMX_STAAS Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
sp|Q8NVA9|FEMX_STAAW Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
dbj|BAB96045.1| FmhB protein [Staphylococcus aureus subsp. aureus MW2]
emb|CAG43963.1| putative peptidoglycan pentaglycine interpeptide biosynthesis
protein [Staphylococcus aureus subsp. aureus MSSA476]
Length = 421
Score = 120 bits (302), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 105/410 (25%), Positives = 191/410 (46%), Gaps = 39/410 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK H +LQ + WA+ K W RI + ++ + LL K +
Sbjct: 3 KMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V+DY +++ + + + K+ K +KA IK DP +
Sbjct: 63 PKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDV----------- 111
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANIYTQEN---LEMQFPKHTRRL 181
E A++NL+ G G ++ D IQPR +N L F + R
Sbjct: 112 -EVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R + L F++++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITR------TQAHQKKRLKKL----EDQKASLERYIT 288
L K++ + + + Q+L ++ +I + T Q K+ + + +++ A E
Sbjct: 230 LVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKR 289
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ E ++PE + ++G L + G+ LY +++F+ F P + + + + A + G
Sbjct: 290 DLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGA 349
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 TTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQL 399
>ref|NP_372786.1| FmhB protein [Staphylococcus aureus subsp. aureus Mu50]
ref|NP_375375.1| FmhB protein [Staphylococcus aureus subsp. aureus N315]
ref|YP_001247644.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
ref|YP_001317441.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
ref|YP_001442836.1| FmhB protein [Staphylococcus aureus subsp. aureus Mu3]
sp|Q7A2M4|FEMX_STAAM Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
sp|Q7A447|FEMX_STAAN Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
sp|P0C1Q0|FEMX_STAAU Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
gb|AAD23961.1|AF106850_1 FmhB [Staphylococcus aureus]
dbj|BAB43354.1| FmhB protein [Staphylococcus aureus subsp. aureus N315]
dbj|BAB58424.1| FmhB protein [Staphylococcus aureus subsp. aureus Mu50]
gb|ABQ50068.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
gb|ABR53154.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
dbj|BAF79129.1| FmhB protein [Staphylococcus aureus subsp. aureus Mu3]
Length = 421
Score = 120 bits (302), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 105/410 (25%), Positives = 191/410 (46%), Gaps = 39/410 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK H +LQ + WA+ K W RI + ++ + LL K +
Sbjct: 3 KMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V+DY +++ + + + K+ K +KA IK DP +
Sbjct: 63 PKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDV----------- 111
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANIYTQEN---LEMQFPKHTRRL 181
E A++NL+ G G ++ D IQPR +N L F + R
Sbjct: 112 -EVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R + L F++++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITR------TQAHQKKRLKKL----EDQKASLERYIT 288
L K++ + + + Q+L ++ +I + T Q K+ + + +++ A E
Sbjct: 230 LVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKR 289
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ E ++PE + ++G L + G+ LY +++F+ F P + + + + A + G
Sbjct: 290 DLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGA 349
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 TTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQL 399
>ref|YP_187061.1| femX protein [Staphylococcus aureus subsp. aureus COL]
sp|Q5HDU6|FEMX_STAAC Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
gb|AAF14182.2|AF105976_1 FmhB [Staphylococcus aureus]
gb|AAW37126.1| femX protein [Staphylococcus aureus subsp. aureus COL]
Length = 421
Score = 119 bits (298), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 104/410 (25%), Positives = 190/410 (46%), Gaps = 39/410 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK H +LQ + WA+ K W RI + ++ + LL K +
Sbjct: 3 KMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V+DY +++ + + + K+ K +K IK DP + + +
Sbjct: 63 PKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKTYAIKIDPDVEVDK------- 115
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANIYTQEN---LEMQFPKHTRRL 181
A++NL+ G G ++ D IQPR +N L F + R
Sbjct: 116 -----GTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R + L F++++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITRTQAHQK---KRLKKLEDQKASLERYIT------- 288
L K++ + + + Q+L ++ +I + Q K K+ KK ++ + I
Sbjct: 230 LVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKR 289
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ E ++PE + ++G L + G+ LY +++F+ F P + + + + A + G
Sbjct: 290 DLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGA 349
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 TTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQL 399
>ref|YP_417591.1| methicillin resistance factor peptidoglycan pentaglycine
interpeptide biosynthetic protein [Staphylococcus aureus
RF122]
sp|Q2YYN5|FEMX_STAAB Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
emb|CAI81823.1| methicillin resistance factor peptidoglycan pentaglycine
interpeptide biosynthetic protein [Staphylococcus aureus
RF122]
Length = 421
Score = 119 bits (297), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 104/410 (25%), Positives = 191/410 (46%), Gaps = 39/410 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK H +LQ + WA+ K W RI + ++ + LL K +
Sbjct: 3 KMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V+DY +++ + + + K+ K +KA IK DP +
Sbjct: 63 PKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDV----------- 111
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANIYTQEN---LEMQFPKHTRRL 181
E A++NL+ G G ++ D IQPR +N L + + R
Sbjct: 112 -EVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSYERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R + L F++++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITR------TQAHQKKRLKKL----EDQKASLERYIT 288
L K++ + + + Q+L ++ +I + T Q K+ + + +++ A E
Sbjct: 230 LVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKR 289
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ E ++PE + ++G L + G+ LY +++F+ F P + + + + A + G
Sbjct: 290 DLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGA 349
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 TTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQL 399
>ref|YP_041701.1| putative peptidoglycan pentaglycine interpeptide biosynthesis
protein [Staphylococcus aureus subsp. aureus MRSA252]
sp|Q6GEH2|FEMX_STAAR Aminoacyltransferase femX (Factor essential for expression of
methicillin resistance X)
emb|CAG41327.1| putative peptidoglycan pentaglycine interpeptide biosynthesis
protein [Staphylococcus aureus subsp. aureus MRSA252]
Length = 421
Score = 117 bits (294), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 104/410 (25%), Positives = 191/410 (46%), Gaps = 39/410 (9%)
Query: 9 KIGISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
K+ I+ +EHD+FVK + +LQ + WA+ K W RI + ++ + LL K +
Sbjct: 3 KMHITNQEHDAFVKSNPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKV 62
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P L ++ YI RG V+DY +++ + + + K+ K +KA IK DP +
Sbjct: 63 PKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDV----------- 111
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQANIYTQEN---LEMQFPKHTRRL 181
E A++NL+ G G ++ D IQPR +N L F + R
Sbjct: 112 -EVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSK 170
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY---GDKAYLH 238
++ A +RG R + L F++++ +T +R R+ +YF+ + GD A L
Sbjct: 171 VRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGD-AELF 229
Query: 239 LAKVNIPQKLDQYRQQLILINQDITR------TQAHQKKRLKKL----EDQKASLERYIT 288
L K++ + + + Q+L ++ +I + T Q K+ + + +++ A E
Sbjct: 230 LVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKR 289
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ E ++PE + ++G L + G+ LY +++F+ F P + + + + A + G
Sbjct: 290 DLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGA 349
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHI 392
+ GG + D GL FK + + E IGEF+ ++ PLY +
Sbjct: 350 TTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQL 399
>gb|AAY84721.1| MurB9 [Streptococcus pneumoniae]
Length = 121
Score = 115 bits (288), Expect = 6e-24, Method: Compositional matrix adjust.
Identities = 49/121 (40%), Positives = 84/121 (69%)
Query: 63 IKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG 122
I+ LPLG + Y+PRGP++DY D +L++F ++++K Y ++K+A+F+ +DP+I L Q+ +
Sbjct: 1 IRALPLGYKMFYVPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQHLVN 60
Query: 123 QEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLI 182
Q++ E P L+ ++ L + GV W+G T E+ D+IQPR QA IY + E + K T++ I
Sbjct: 61 QDKTEYPEKLSIVEILGQLGVKWSGRTTEMDDTIQPRIQAKIYKENFEEDKLSKSTKQAI 120
Query: 183 K 183
+
Sbjct: 121 R 121
>ref|YP_188525.1| femB protein [Staphylococcus epidermidis RP62A]
sp|Q5HPG5|FEMB_STAEQ Aminoacyltransferase femB
gb|AAW54350.1| femB protein [Staphylococcus epidermidis RP62A]
Length = 417
Score = 114 bits (284), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 102/385 (26%), Positives = 178/385 (46%), Gaps = 39/385 (10%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+G+ ++ +V + SL K+ +G + Y RGPVMDY D LV F +K L Y + L
Sbjct: 44 LGVKDDDNRVIAASLFSKIPTMGSYVYYSNRGPVMDYSDLGLVDFYLKELDKYLHQHQCL 103
Query: 107 FIKYDPAILLKQYALGQEEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L + Y +++ PL A + + G G T + S Q R+
Sbjct: 104 YVKLDPYWLYQVY----DKDINPLTEKNDALVNLFKSHGYDHHGFTTQYDSSSQVRWMGV 159
Query: 164 I----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T +L +F +R I A GVK +S+ E F + TE R + +
Sbjct: 160 LDLEGKTPASLRKEFDSQRKRNINKAINYGVKVRFLSKDEFDLFLDLYRETEARTGFASK 219
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + YGDK + LA ++ L++Y Q L Q+ + +++ + E++
Sbjct: 220 TDDYFYNFIEHYGDKVLVPLAYID----LNEYIQHL----QESLNDKENRRDDMMAKENK 271
Query: 280 KASLERYITEFEGFTDQYPEEVVVAG--------ILSISYG----NVMEMLY--AGMNDD 325
+ I E + D +E++ A IL+++ G N E+ Y G ++
Sbjct: 272 TDKQLKKIAELDKQIDHDKKELLQASELRQTDGEILNLASGVYFANAYEVNYFSGGSSEK 331
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ ++ Y ++ ++ + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 332 YNQYMGPYAMHWHMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVRIEELIG 391
Query: 381 EFNLPVSPL-YHIANTMYKIRKQLK 404
+F P++ + Y + NT+ +IR +LK
Sbjct: 392 DFYKPINKVKYWLFNTLDRIRNKLK 416
>ref|NP_764613.1| FemB protein [Staphylococcus epidermidis ATCC 12228]
sp|Q8CPA8|FEMB_STAES Aminoacyltransferase femB
gb|AAO04655.1|AE016747_152 FemB protein [Staphylococcus epidermidis ATCC 12228]
Length = 417
Score = 114 bits (284), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 102/385 (26%), Positives = 178/385 (46%), Gaps = 39/385 (10%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+G+ ++ +V + SL K+ +G + Y RGPVMDY D LV F +K L Y + L
Sbjct: 44 LGVKDDDNRVIAASLFSKIPTMGSYVYYSNRGPVMDYSDLGLVDFYLKELDKYLHQHQCL 103
Query: 107 FIKYDPAILLKQYALGQEEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L + Y +++ PL A + + G G T + S Q R+
Sbjct: 104 YVKLDPYWLYQVY----DKDINPLTEKNDALVNLFKSHGYDHHGFTTQYDSSSQVRWMGV 159
Query: 164 I----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T +L +F +R I A GVK +S+ E F + TE R + +
Sbjct: 160 LDLEGKTPASLRKEFDSQRKRNINKAINYGVKVRFLSKDEFDLFLDLYRETEARTGFASK 219
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + YGDK + LA ++ L++Y Q L Q+ + +++ + E++
Sbjct: 220 TDDYFYNFIEHYGDKVLVPLAYID----LNEYIQHL----QESLNDKENRRDDMMAKENK 271
Query: 280 KASLERYITEFEGFTDQYPEEVVVAG--------ILSISYG----NVMEMLY--AGMNDD 325
+ I E + D +E++ A IL+++ G N E+ Y G ++
Sbjct: 272 TDKQLKKIAELDKQIDHDKKELLQASELRQTDGEILNLASGVYFANAYEVNYFSGGSSEK 331
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ ++ Y ++ ++ + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 332 YNQYMGPYAMHWHMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVRIEELIG 391
Query: 381 EFNLPVSPL-YHIANTMYKIRKQLK 404
+F P++ + Y + NT+ +IR +LK
Sbjct: 392 DFYKPINKVKYWLFNTLDRIRNKLK 416
>sp|P95735|FEMB_STAEP Aminoacyltransferase femB
gb|AAB41948.1| FEMB [Staphylococcus epidermidis]
Length = 417
Score = 114 bits (284), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 102/385 (26%), Positives = 178/385 (46%), Gaps = 39/385 (10%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+G+ ++ +V + SL K+ +G + Y RGPVMDY D LV F +K L Y + L
Sbjct: 44 LGVKDDDNRVIAASLFSKIPTMGSYVYYSNRGPVMDYSDLGLVDFYLKELDKYLHQHQCL 103
Query: 107 FIKYDPAILLKQYALGQEEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L + Y +++ PL A + + G G T + S Q R+
Sbjct: 104 YVKLDPYWLYQVY----DKDINPLTEKNDALVNLFKSHGYDHHGFTTQYDSSSQVRWMGV 159
Query: 164 I----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T +L +F +R I A GVK +S+ E F + TE R + +
Sbjct: 160 LDLEGKTPASLRKEFDSQRKRNINKAINYGVKVRFLSKDEFGLFLDLYRETEARTGFASK 219
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + YGDK + LA ++ L++Y Q L Q+ + +++ + E++
Sbjct: 220 TDDYFYNFIEHYGDKVLVPLAYID----LNEYIQHL----QESLNDKENRRDDMMAKENK 271
Query: 280 KASLERYITEFEGFTDQYPEEVVVAG--------ILSISYG----NVMEMLY--AGMNDD 325
+ I E + D +E++ A IL+++ G N E+ Y G ++
Sbjct: 272 TDKQLKKIAELDKQIDHDKKELLQASELRQTDGEILNLASGVYFANAYEVNYFSGGSSEK 331
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ ++ Y ++ ++ + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 332 YNQYMGPYAMHWHMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVRIEELIG 391
Query: 381 EFNLPVSPL-YHIANTMYKIRKQLK 404
+F P++ + Y + NT+ +IR +LK
Sbjct: 392 DFYKPINKVKYWLFNTLDRIRNKLK 416
>gb|ACA97855.1| serine/alanine adding enzyme [Streptococcus pneumoniae]
Length = 116
Score = 112 bits (281), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 50/115 (43%), Positives = 78/115 (67%)
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G I Y+PRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 1 GYKIFYVPRGPILDYGDTELLNFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKIEF 60
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
P LA I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+
Sbjct: 61 PENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIR 115
>gb|ACA97854.1| serine/alanine adding enzyme [Streptococcus pneumoniae]
Length = 116
Score = 112 bits (281), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 49/115 (42%), Positives = 78/115 (67%)
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
G + YIPRGP++DY D +L+ F ++++K Y ++K+A+F+ +DP+I L Q + QE+ E
Sbjct: 1 GYKMFYIPRGPILDYRDIELLKFVLQSIKSYARSKRAIFVTFDPSICLSQSLINQEKTEF 60
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIK 183
P +A I +LQ+ GV W+G T E+ D+IQPR QA IY + E + K T++ I+
Sbjct: 61 PENMAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIR 115
>ref|YP_001727511.1| FemAB family protein [Leuconostoc citreum KM20]
gb|ACA82067.1| FemAB family protein [Leuconostoc citreum KM20]
Length = 417
Score = 112 bits (281), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 92/362 (25%), Positives = 171/362 (47%), Gaps = 23/362 (6%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
IG+ +E+ VA+ +L + G S+ RGP++D+ DR L F + + + K + AL
Sbjct: 45 IGVKHDERVVAAALVLTETTRFG-SVFLFDRGPLIDFNDRALCHFFVTKSRQFAKQRGAL 103
Query: 107 FIKYDPAI--LLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ--- 161
+I++ P + L+ ++ +A + L G T ++ + P ++
Sbjct: 104 YIEWTPNVTYLVTNNKGDMQQSVNDSFMATMSGL---GFQHEPFTFGMSTTGSPSWEYVK 160
Query: 162 --ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+++ ++++ + K+ + +K KQ G++ +S+++L F + T +R + +
Sbjct: 161 DISDLSDEKSILKSYSKNVQYYLKKNKQFGIQLRELSRTDLPSFKALTESTAERLHYHDK 220
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIP-------QKLDQYRQQLILINQDITR--TQAHQK 270
+ A+++ + YGD A A++N K+ Q+L IN+ I++ Q K
Sbjct: 221 DLAFYESIYDIYGDDAIFVFAELNFETYIASERDKVSALEQKLAKINEKISKYPNQDKFK 280
Query: 271 KRLKKLEDQKASLERYITEF-EGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKF 329
++ + EDQK + I + + F+D VVVAG L I M LY+G + +K +
Sbjct: 281 RQYHEFEDQKQHHSQRIQKATKQFSDAGQATVVVAGALFIKQPQEMTYLYSGTYEAYKDY 340
Query: 330 YPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVS 387
Y Y + + + A GI N G+ G D DG+ FK F + +G F LPV
Sbjct: 341 YGPYQIQDMMIRRAVALGIPRYNFYGISGRFDGSDGVLGFKTAFEGHARQLVGRFILPVR 400
Query: 388 PL 389
PL
Sbjct: 401 PL 402
>ref|ZP_00997195.1| putative peptidoglycan pentaglycine interpeptide
biosynthesisprotein [Janibacter sp. HTCC2649]
gb|EAP97052.1| putative peptidoglycan pentaglycine interpeptide
biosynthesisprotein [Janibacter sp. HTCC2649]
Length = 408
Score = 112 bits (281), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 101/420 (24%), Positives = 188/420 (44%), Gaps = 42/420 (10%)
Query: 8 AKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYK--------EEKQVA 57
+ + ++E EHD FV++H ++Q + W K K W + + + + +E A
Sbjct: 4 SALSLTEREHDDFVRDHPNGHLMQTTPWGKEKEHTGWTWKTVAVGRKGAGPDGADEVTGA 63
Query: 58 SLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLK 117
+L L + + ++ Y PRG V+D+ D + V + + K + + ++ DPA+ +
Sbjct: 64 ALILFRRTPVVPMALAYCPRGFVVDWADAEAVDALLAEVTKVAKENRGVLLRIDPAVRID 123
Query: 118 QYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSI-QP--RFQANIYTQENLEMQF 174
+ +P L+ G T + A ++ QP R +I E L
Sbjct: 124 NPDI------RPA-------LESRGFTRTDPGDDAAKTLAQPALRMVTDISDLEALHKDL 170
Query: 175 PKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKL--MTTYG 232
+ TR+ I+ A++ G+ V + ++ F +++ T R +R+ YF L + +
Sbjct: 171 TQGTRQSIRKAEKSGLVYESVGRDKIPAFYELMKTTGARDGFGIRSMEYFTTLYDVLSPT 230
Query: 233 DKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKK-RLKKLEDQKASLERYI---- 287
D + L K++ + R +L + + + A ++K +K + Q A LE I
Sbjct: 231 DDIVISLVKLDHGAAAEAARAKLEDLRGQLEKAAAKREKYPSEKADRQVAGLEESIEKNE 290
Query: 288 ---TEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAY 344
EFE ++P+ +AG + + G LYA +D+ + P YL+ + QDA
Sbjct: 291 GSAAEFEASHAKHPDGQYLAGSVFATCGTRGSYLYAASSDEHRNLRPNYLMVWQIMQDAA 350
Query: 345 QDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLY----HIANTMYKIR 400
G+ + GG++ S +GL +FK + P E+ GEF + PL +A +YK R
Sbjct: 351 AKGVTTFDFGGIDAS--EGLEEFKRQWNPERREYAGEFTKQLRPLSGRLIDLAVRVYKRR 408
>gb|AAB53784.1| lysostaphin immunity factor [Staphylococcus simulans]
Length = 413
Score = 112 bits (280), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 108/409 (26%), Positives = 182/409 (44%), Gaps = 30/409 (7%)
Query: 7 YAKIGISEEEHDSFVKEHQQIS-VLQGSDWAKIKNQWQN--ERIGIYKEEKQVASLSLLI 63
++K+ I E E F Q++S Q + + +N QN +G+ E +V + LL
Sbjct: 3 FSKLNIQEFEEFVF----QKMSHYTQSASHFEYRNNHQNNVHLVGVKNETGEVLAACLLT 58
Query: 64 KLLPLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG 122
+ L Y RGPVM++ D +LV F + L Y K + L++ DP +L +
Sbjct: 59 EARCLKFFKYFYTHRGPVMNFKDHELVRFFYENLTTYLKKQNCLYVLTDPYLLENIRSCD 118
Query: 123 QE--EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK---- 176
E E + NL G G T + + Q R+ + + + E Q K
Sbjct: 119 GEILESYDNETFMNVMNL--LGYRHQGFTTGYSQTSQIRWLSVLNLENKDEKQLLKEMDY 176
Query: 177 HTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAY 236
TRR IK + VK +S +E +F K+ + E++ R ++YF+++ TY D +
Sbjct: 177 QTRRNIKKTYEMQVKVRDLSINETDRFFKLFKMAEEKHGFKFREQSYFERMQKTYADNSM 236
Query: 237 LHLAKVNIPQKLDQYRQQLILINQDITRTQA---------HQKKRLKKLEDQKASLERYI 287
L LA +++ + L+ ++ +N DI QA K + + + Q A+ ER I
Sbjct: 237 LKLAYIDLEELLETQNAKVAELNTDIENIQAALKENPNSKKNKNKYAQYQKQLAAQERKI 296
Query: 288 TEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDG 347
TE + + + +A I + + L +G N + + Y L + Q A G
Sbjct: 297 TETKKLIETDGPVLDLAAAYYIYTPHEVYYLSSGSNPKYNAYMGAYRLQWEMIQFAKNKG 356
Query: 348 IIWANMGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSPLYH 391
I N G+ G D G+ KFK F +EE++G+F P+ PL++
Sbjct: 357 INRYNFYGITGDFSEDAEDFGVQKFKEGFNAHVEEYVGDFIKPIKPLFY 405
>gb|AAD23963.1|AF106851_2 FmhC [Staphylococcus aureus]
Length = 414
Score = 111 bits (278), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 107/410 (26%), Positives = 187/410 (45%), Gaps = 23/410 (5%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNER--IGIYKEEKQVASLSLLIKLLPLG 69
+SEEE ++ K+H + Q + +N+ +E +G+ ++ +V + LL +
Sbjct: 6 LSEEEFTNYTKKHFK-HYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFK 64
Query: 70 -RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
Y RGP++DY D LV + K L + + +FI DP ++ +
Sbjct: 65 FYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRLIKD 184
+K L + G G T ++ Q R+ + + ++ E Q K TRR IK
Sbjct: 125 YNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKK 184
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
+ GVK +S E ++F K+ + E++ NE YF+++ Y DKA L +A +N+
Sbjct: 185 TIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINL 244
Query: 245 PQKLDQYRQQLILI-NQDITRTQA--------HQKKRLKKLEDQKASLERYITEFEGFTD 295
+ D+ + QL+ I N+ +T +A K +L +L Q +S+ I++ E
Sbjct: 245 NEYQDKLKIQLLKIENEMMTVNRALNENPNSKRNKSKLNQLNMQLSSINNRISKTEELIL 304
Query: 296 QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ + +A L I + + L +G N + ++ Y L ++ + A I N G
Sbjct: 305 EDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYG 364
Query: 356 VEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKI 399
+ G D G+ +FK F +EE IG+F PV P LY A +YK+
Sbjct: 365 ITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>ref|NP_645948.1| FmhC protein [Staphylococcus aureus subsp. aureus MW2]
ref|YP_043308.1| FemAB family protein [Staphylococcus aureus subsp. aureus MSSA476]
ref|YP_186123.1| endopeptidase resistance gene [Staphylococcus aureus subsp. aureus
COL]
ref|YP_493838.1| endopeptidase resistance gene [Staphylococcus aureus subsp. aureus
USA300]
ref|YP_499756.1| hypothetical protein SAOUHSC_01220 [Staphylococcus aureus subsp.
aureus NCTC 8325]
ref|YP_001332192.1| methicillin resistance-related protein FmhC [Staphylococcus aureus
subsp. aureus str. Newman]
ref|YP_001575073.1| FemAB family peptidoglycan biosynthesis protein [Staphylococcus
aureus subsp. aureus USA300_TCH1516]
ref|ZP_02759715.1| FemAB family peptidoglycan biosynthesis protein [Staphylococcus
aureus subsp. aureus USA300_TCH1516]
dbj|BAA33857.1| Eprh [Staphylococcus aureus]
dbj|BAB94996.1| FmhC protein [Staphylococcus aureus subsp. aureus MW2]
emb|CAG42959.1| FemAB family protein [Staphylococcus aureus subsp. aureus MSSA476]
gb|AAW38097.1| endopeptidase resistance gene [Staphylococcus aureus subsp. aureus
COL]
gb|ABD20618.1| endopeptidase resistance gene [Staphylococcus aureus subsp. aureus
USA300_FPR3757]
gb|ABD30324.1| conserved hypothetical protein [Staphylococcus aureus subsp. aureus
NCTC 8325]
dbj|BAF67430.1| methicillin resistance-related protein FmhC [Staphylococcus aureus
subsp. aureus str. Newman]
gb|ABX29194.1| FemAB family peptidoglycan biosynthesis protein [Staphylococcus
aureus subsp. aureus USA300_TCH1516]
Length = 414
Score = 111 bits (277), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 107/410 (26%), Positives = 187/410 (45%), Gaps = 23/410 (5%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNER--IGIYKEEKQVASLSLLIKLLPLG 69
+SEEE ++ K+H + Q + +N+ +E +G+ ++ +V + LL +
Sbjct: 6 LSEEEFTNYTKKHFK-HYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFK 64
Query: 70 -RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
Y RGP++DY D LV + K L + + +FI DP ++ +
Sbjct: 65 FYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRLIKD 184
+K L + G G T ++ Q R+ + + ++ E Q K TRR IK
Sbjct: 125 YNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKK 184
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
+ GVK +S E ++F K+ + E++ NE YF+++ Y DKA L +A +N+
Sbjct: 185 TIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINL 244
Query: 245 PQKLDQYRQQLILI-NQDITRTQA--------HQKKRLKKLEDQKASLERYITEFEGFTD 295
+ D+ + QL+ I N+ +T +A K +L +L Q +S+ I++ E
Sbjct: 245 NEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIF 304
Query: 296 QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ + +A L I + + L +G N + ++ Y L ++ + A I N G
Sbjct: 305 EDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYG 364
Query: 356 VEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKI 399
+ G D G+ +FK F +EE IG+F PV P LY A +YK+
Sbjct: 365 ITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>ref|NP_371772.1| FmhC protein [Staphylococcus aureus subsp. aureus Mu50]
ref|NP_374364.1| FmhC protein [Staphylococcus aureus subsp. aureus N315]
ref|YP_001246682.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
ref|YP_001316472.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
ref|YP_001441828.1| FmhC protein [Staphylococcus aureus subsp. aureus Mu3]
dbj|BAB42343.1| FmhC protein [Staphylococcus aureus subsp. aureus N315]
dbj|BAB57410.1| FmhC protein [Staphylococcus aureus subsp. aureus Mu50]
gb|ABQ49106.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
gb|ABR52185.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
dbj|BAF78121.1| FmhC protein [Staphylococcus aureus subsp. aureus Mu3]
Length = 414
Score = 111 bits (277), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 107/410 (26%), Positives = 187/410 (45%), Gaps = 23/410 (5%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNER--IGIYKEEKQVASLSLLIKLLPLG 69
+SEEE ++ K+H + Q + +N+ +E +G+ ++ +V + LL +
Sbjct: 6 LSEEEFTNYTKKHFK-HYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFK 64
Query: 70 -RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
Y RGP++DY D LV + K L + + +FI DP ++ +
Sbjct: 65 FYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRLIKD 184
+K L + G G T ++ Q R+ + + ++ E Q K TRR IK
Sbjct: 125 YNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKK 184
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
+ GVK +S E ++F K+ + E++ NE YF+++ Y DKA L +A +N+
Sbjct: 185 TIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINL 244
Query: 245 PQKLDQYRQQLILI-NQDITRTQA--------HQKKRLKKLEDQKASLERYITEFEGFTD 295
+ D+ + QL+ I N+ +T +A K +L +L Q +S+ I++ E
Sbjct: 245 NEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIL 304
Query: 296 QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ + +A L I + + L +G N + ++ Y L ++ + A I N G
Sbjct: 305 EDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYG 364
Query: 356 VEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKI 399
+ G D G+ +FK F +EE IG+F PV P LY A +YK+
Sbjct: 365 ITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>ref|YP_040635.1| FemAB family protein [Staphylococcus aureus subsp. aureus MRSA252]
emb|CAG40226.1| FemAB family protein [Staphylococcus aureus subsp. aureus MRSA252]
Length = 414
Score = 110 bits (275), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 106/410 (25%), Positives = 187/410 (45%), Gaps = 23/410 (5%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNER--IGIYKEEKQVASLSLLIKLLPLG 69
+SEEE ++ K+H + Q + +N+ +E +G+ ++ +V + LL +
Sbjct: 6 LSEEEFTNYTKKHFK-HYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFK 64
Query: 70 -RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
Y RGP++DY D LV + K L + + +FI DP ++ +
Sbjct: 65 FYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKN 124
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRLIKD 184
+K L + G G T ++ Q R+ + + ++ E Q K TRR IK
Sbjct: 125 YNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKK 184
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
+ GVK +S E ++F K+ + E++ NE YF+++ Y DKA L +A +++
Sbjct: 185 TIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACIDL 244
Query: 245 PQKLDQYRQQLILI-NQDITRTQA--------HQKKRLKKLEDQKASLERYITEFEGFTD 295
+ D+ + QL+ I N+ +T +A K +L +L Q +S+ I++ E
Sbjct: 245 NEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIL 304
Query: 296 QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ + +A L I + + L +G N + ++ Y L ++ + A I N G
Sbjct: 305 EDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYG 364
Query: 356 VEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKI 399
+ G D G+ +FK F +EE IG+F PV P LY A +YK+
Sbjct: 365 ITGVFSDEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>ref|NP_721139.1| putative peptidoglycan branched peptide synthesis protein; alanine
adding enzyme; beta-lactam resistance factor MurN
[Streptococcus mutans UA159]
gb|AAN58445.1|AE014914_7 putative peptidoglycan branched peptide synthesis protein; alanine
adding enzyme; beta-lactam resistance factor MurN
[Streptococcus mutans UA159]
Length = 410
Score = 110 bits (274), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 113/415 (27%), Positives = 197/415 (47%), Gaps = 34/415 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL-GR 70
IS+ + V++ +Q S +Q + AK+ ++ I E +S ++ +P+ G
Sbjct: 6 ISQNDFALHVQKAEQKSFMQTLEMAKLLSKRGFTLNYIAWLENGTIEISAILYSMPMTGG 65
Query: 71 SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPL 130
I GPV+ D+ L F + LKDY K K AL +++K Y Q +
Sbjct: 66 RYFEINCGPVVT-RDKHLTDF-YRELKDYVKEKGAL------ELVIKPYDTYQTFDGDGQ 117
Query: 131 ALAA-----IKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHTRR 180
A +A I L G H+ GL + + +P + ++I +++ L F K R
Sbjct: 118 ATSAEKKELISQLTNLGYHFDGLQRDYPNG-EPDWHYVKDLSDI-SEQTLLKSFSKKGRP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K AK G K R+++ EL+ F +I S T R+ S ++ Y+Q ++G+ A +A
Sbjct: 176 LVKKAKTFGTKLRRLNRDELNLFKEITSATSDRREYSDKSLDYYQDFYDSFGNNAEFMIA 235
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQA------HQKKRLKKLEDQKASLERYIT---EFE 291
+N L ++ + I + QA H +K+ +L + + + + T E +
Sbjct: 236 SLNFENYLSHLQRDQNKLGNKIAKLQADLEKNPHSEKKQNQLRELSSQFDTFTTRQEEAQ 295
Query: 292 GFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
F +Y ++V++AG L + L++G +F KFY LL +V +A + GI +
Sbjct: 296 KFITKYGKKDVILAGSLFVYTPQEAVYLFSGSYPEFNKFYAPALLQEHVMLEALKRGISF 355
Query: 351 ANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMYKIRKQ 402
N+ G+ G D DG+ +FK NF I +G F+ +PL Y + NT+ KI ++
Sbjct: 356 YNLLGITGHFDNSDGVLRFKQNFNGYIVRKMGTFHYYPNPLKYRLLNTIKKILRR 410
>ref|NP_815813.1| FemAB family protein [Enterococcus faecalis V583]
gb|AAO81883.1| FemAB family protein [Enterococcus faecalis V583]
Length = 426
Score = 108 bits (271), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 104/410 (25%), Positives = 187/410 (45%), Gaps = 33/410 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++E+E +F H + L+ + + + W E +G+ +E + +A+ L K + +G
Sbjct: 21 LTEQEFTTFAMTHPAGNFLETPEMKHLLERRGWHCEYVGVKREGQLIAACILSKKKVKIG 80
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDP--AILLKQYALGQEEEE 127
+ I G +MDY D+ V LK Y K L++ + P I L+ + G+ E+
Sbjct: 81 YAFD-IDGGILMDYTDKKCVEAFFTGLKKYVKKNDGLYLTFTPNKQICLRDFNGGEVEK- 138
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF-----QANIYTQENLEMQFPKHTRRLI 182
+ G G + D PR+ A + T+E+L + K + I
Sbjct: 139 --VNQETFDYFTSIGFEHQGFDVHNFDG-APRWLFVKDMAGL-TEEDLWKSYGKDAKYDI 194
Query: 183 KDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKV 242
K + GV + EL F K+ T R+N ++ AY+Q + +G++A +A++
Sbjct: 195 KKTWEYGVTIRELRYEELPLFKKLTEETSARRNFEDKDLAYYQAVYEEFGERAKFMVAEL 254
Query: 243 -------NIPQKLDQYRQQLILINQDITRTQAHQKKRLKK--LEDQKASLERYITEF-EG 292
N+ +KL + ++ L +N+ + +KK +K ED+ ++ + I E E
Sbjct: 255 NFATYLENLHEKLRKLQETLNEVNEALIANPKSRKKNNQKREFEDEVRTVRKRIDEAKEM 314
Query: 293 FTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWAN 352
T PE ++AG L I + + L++G + +K++Y YL+ + ++ I N
Sbjct: 315 KTSDEPE--ILAGALFIVHPQEVVYLFSGTYEKYKQYYAPYLIQHKMLTYTVENNIPKYN 372
Query: 353 MGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSP----LYHIANTM 396
GV+G D DG+ KFK +F +EE +G F P LYH T+
Sbjct: 373 FYGVDGIFDGSDGVLKFKQSFGGHVEELMGNFQWKAKPMKYALYHALKTI 422
>ref|YP_189557.1| fmhA protein [Staphylococcus epidermidis RP62A]
gb|AAW52801.1| fmhA protein [Staphylococcus epidermidis RP62A]
Length = 415
Score = 108 bits (270), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 111/419 (26%), Positives = 185/419 (44%), Gaps = 30/419 (7%)
Query: 10 IGISEEEHDSFVKE---HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLL 66
+ ++ EE + F E H S + ++ +K K +G+ +++ V + LL +
Sbjct: 4 VNLTSEEFEQFTSENFSHYTQSSIHYNNRSKTKGDVH--LVGVKDDQEDVIAACLLTEAR 61
Query: 67 PLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
L Y RGPVMD+ + LV F K+L Y K L++ DP +L E
Sbjct: 62 SLKFFKYFYTHRGPVMDFNNLVLVRFFFKSLTAYLKKHNCLYVLVDPYVLENLRQPNGEI 121
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRL 181
E A IK ++E G G T+ Q R+ + + ++ E Q K TRR
Sbjct: 122 IESFDNRALIKTMEELGYKHQGYTVGYDTMSQIRWLSVLNLKDKSEDQLLKEMDYQTRRN 181
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
IK + GVK + E + F ++ + E++ R E YF ++ TY D A L LA
Sbjct: 182 IKKTYEMGVKVKTLPIEETNTFFELFKMAEEKHGFKFREEPYFVEMQKTYEDHAMLKLAY 241
Query: 242 VNIPQKLDQYRQQLILINQ---DITRT---QAHQKKRLKKLEDQKASLERYITEFEGFTD 295
+++ LD + + +NQ D+ +T + KK K K + + +
Sbjct: 242 IDLQDYLDTLQTKHQNLNQQLKDVEKTLEENPNSKKNKTKHTQVKQQFDSNARKIRQTKE 301
Query: 296 QYPEE---VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWAN 352
+ EE + +A L I + + L +G N + + Y L ++ Q A + I N
Sbjct: 302 KIAEEGQVLHLAAALYIYNDHEVYYLSSGSNPKYNAYMGAYRLQWDMIQFAKEHNIDRYN 361
Query: 353 MGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNK 406
GV G D G+ KFK F I E+IG+F P+ PL+ YK++++L+++
Sbjct: 362 FYGVTGDFSENAEDAGVQKFKEGFNAKIYEYIGDFIKPIKPLF------YKVKQELESR 414
>ref|YP_301460.1| FemB protein [Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305]
dbj|BAE18515.1| FemB protein [Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305]
Length = 419
Score = 108 bits (269), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 98/383 (25%), Positives = 179/383 (46%), Gaps = 33/383 (8%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+G+ ++ QV + SL K+ +G + Y RGPVMDY D LV F ++ L Y + L
Sbjct: 44 LGLKDDDNQVIAASLFSKIPTMGSYVYYSNRGPVMDYNDLGLVDFYLRELDTYLQQHNCL 103
Query: 107 FIKYDPAILLKQYALGQEEEEKPLALA----AIKNLQEAG--VHWTGLTMEIADSIQPRF 160
++K DP + + Y +++ PL A+ NL ++ +H G T S Q R+
Sbjct: 104 YVKMDPYWIYQIY----DKDINPLPNHDKNDALVNLFKSHRYIH-HGFTTSYDTSSQVRW 158
Query: 161 QANIY----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNI 216
+ T +L+ QF +R I A GVK +++ E F ++ TE+R
Sbjct: 159 MGVLNLDGETPASLKKQFDSQRKRNINKAINFGVKVRLLTRDEFDIFLELYRETEERTGF 218
Query: 217 SLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITR------TQAHQK 270
+ + YF + YGDKA + LA +++ + ++ ++ IN+ +R +
Sbjct: 219 VSKTDEYFYNFIDNYGDKALIPLAYIDLDEYINHTQES---INEKESRRDQMMQNENKSD 275
Query: 271 KRLKKLEDQKASLERYITEFEGFTD-QYPEEVVVAGILSISYGNVMEMLY--AGMNDDFK 327
K+LKK+ + +E E ++ + + ++ + + N E+ Y G ++ +
Sbjct: 276 KQLKKIAELDKQIEHDKKELLHASELRLTDGAILNLAAGVYFANAYEVNYFSGGSSEKYN 335
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIGEF 382
++ Y+++ + + G N G+ G S D G+ +FK F IEE IG+F
Sbjct: 336 QYMGPYMMHWYMMNYCFDHGYGRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDF 395
Query: 383 NLPV-SPLYHIANTMYKIRKQLK 404
P+ Y + NT+ +RK++K
Sbjct: 396 YKPIKKSKYWLFNTLNNVRKKIK 418
>ref|NP_371899.1| FemB protein [Staphylococcus aureus subsp. aureus Mu50]
ref|NP_374488.1| FemB protein [Staphylococcus aureus subsp. aureus N315]
ref|YP_040792.1| putative methicillin resistance expression factor [Staphylococcus
aureus subsp. aureus MRSA252]
ref|YP_043439.1| putative methicillin resistance expression factor [Staphylococcus
aureus subsp. aureus MSSA476]
ref|YP_186263.1| femB protein [Staphylococcus aureus subsp. aureus COL]
ref|YP_493967.1| methicillin resistance protein FemB [Staphylococcus aureus subsp.
aureus USA300]
ref|YP_499901.1| methicillin resistance factor, putative [Staphylococcus aureus
subsp. aureus NCTC 8325]
ref|YP_001246806.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
ref|YP_001316602.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
ref|YP_001332321.1| methicillin resistance expression factor FemB [Staphylococcus
aureus subsp. aureus str. Newman]
ref|YP_001441953.1| FemB protein [Staphylococcus aureus subsp. aureus Mu3]
ref|YP_001575201.1| methicillin resistance factor FemB [Staphylococcus aureus subsp.
aureus USA300_TCH1516]
sp|Q6G9I4|FEMB_STAAS Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
sp|Q6GH30|FEMB_STAAR Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
sp|P0A0A6|FEMB_STAAM Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
sp|P0A0A7|FEMB_STAAN Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
sp|P0A0A8|FEMB_STAAU Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
sp|Q5HG44|FEMB_STAAC Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
sp|Q2FYR1|FEMB_STAA8 Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
emb|CAA35680.1| ORF 419 protein [Staphylococcus aureus]
dbj|BAB42467.1| FemB protein [Staphylococcus aureus subsp. aureus N315]
dbj|BAB57537.1| FemB protein [Staphylococcus aureus subsp. aureus Mu50]
emb|CAG40386.1| putative methicillin resistance expression factor [Staphylococcus
aureus subsp. aureus MRSA252]
emb|CAG43092.1| putative methicillin resistance expression factor [Staphylococcus
aureus subsp. aureus MSSA476]
gb|AAW38156.1| femB protein [Staphylococcus aureus subsp. aureus COL]
gb|ABD21376.1| methicillin resistance protein FemB [Staphylococcus aureus subsp.
aureus USA300_FPR3757]
gb|ABD30469.1| methicillin resistance factor, putative [Staphylococcus aureus
subsp. aureus NCTC 8325]
gb|ABQ49230.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
gb|ABR52315.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
dbj|BAF67559.1| methicillin resistance expression factor FemB [Staphylococcus
aureus subsp. aureus str. Newman]
dbj|BAF78246.1| FemB protein [Staphylococcus aureus subsp. aureus Mu3]
gb|ABX29322.1| methicillin resistance factor FemB [Staphylococcus aureus subsp.
aureus USA300_TCH1516]
Length = 419
Score = 108 bits (269), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 98/366 (26%), Positives = 164/366 (44%), Gaps = 36/366 (9%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+GI + +V + SL K+ +G + Y RGPVMD+ D LV + +K L Y + + L
Sbjct: 44 LGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCL 103
Query: 107 FIKYDPAILLKQY---ALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L Y + E EK AL + + G G T E S Q R+
Sbjct: 104 YVKLDPYWLYHLYDKDIVPFEGREKNDALVNL--FKSHGYEHHGFTTEYDTSSQVRWMGV 161
Query: 164 IY----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T E L+ F +R I A GVK + + E + F + TE+R +
Sbjct: 162 LNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSK 221
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + TYGDK + LA ++ LD+Y ++ + Q++ + + + + K E++
Sbjct: 222 TDDYFYNFIDTYGDKVLVPLAYID----LDEY---VLKLQQELNDKENRRDQMMAK-ENK 273
Query: 280 KASLERYITEFEGFTDQYPEEVVVAGILS------------ISYGNVMEMLY--AGMNDD 325
+ I E + D E++ A LS + + N E+ Y G ++
Sbjct: 274 SDKQMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEK 333
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ +F Y+++ + + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 334 YNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIG 393
Query: 381 EFNLPV 386
+F P+
Sbjct: 394 DFYKPI 399
>ref|ZP_02761173.1| methicillin resistance factor FemB [Staphylococcus aureus subsp.
aureus USA300_TCH1516]
Length = 409
Score = 108 bits (269), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 98/366 (26%), Positives = 164/366 (44%), Gaps = 36/366 (9%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+GI + +V + SL K+ +G + Y RGPVMD+ D LV + +K L Y + + L
Sbjct: 34 LGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCL 93
Query: 107 FIKYDPAILLKQY---ALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L Y + E EK AL + + G G T E S Q R+
Sbjct: 94 YVKLDPYWLYHLYDKDIVPFEGREKNDALVNL--FKSHGYEHHGFTTEYDTSSQVRWMGV 151
Query: 164 IY----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T E L+ F +R I A GVK + + E + F + TE+R +
Sbjct: 152 LNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSK 211
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + TYGDK + LA ++ LD+Y ++ + Q++ + + + + K E++
Sbjct: 212 TDDYFYNFIDTYGDKVLVPLAYID----LDEY---VLKLQQELNDKENRRDQMMAK-ENK 263
Query: 280 KASLERYITEFEGFTDQYPEEVVVAGILS------------ISYGNVMEMLY--AGMNDD 325
+ I E + D E++ A LS + + N E+ Y G ++
Sbjct: 264 SDKQMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEK 323
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ +F Y+++ + + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 324 YNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIG 383
Query: 381 EFNLPV 386
+F P+
Sbjct: 384 DFYKPI 389
>ref|NP_563006.1| methicillin resistance factor [Clostridium perfringens str. 13]
ref|ZP_02864740.1| FemAB family protein [Clostridium perfringens C str. JGS1495]
dbj|BAB81796.1| methicillin resistance factor [Clostridium perfringens str. 13]
gb|EDS80391.1| FemAB family protein [Clostridium perfringens C str. JGS1495]
Length = 445
Score = 108 bits (269), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 114/449 (25%), Positives = 201/449 (44%), Gaps = 56/449 (12%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ-VASLSLLIKL 65
Y + I+ E D F + ++ + Q S WA++K W+ + I Y + V + ++L++
Sbjct: 2 YKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
P + + + YIPR DY ++ L+ + L+++ K FI DP I LK E
Sbjct: 62 APYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLK------E 115
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQEN-------LEMQFP 175
EE IKN ++ + + + ++IQP F+ + T+ N + +F
Sbjct: 116 NEEALSEGTEIKNFLKS-LGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFS 174
Query: 176 KHTRRLIKDAKQRG--VKTY---RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTT 230
TR IK A++RG V+ Y +++ L +F +I+ T KR N +R+ YF+ ++
Sbjct: 175 SKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDY 234
Query: 231 YGDKAYLHLAKVNIPQKLDQYRQQL----------------ILINQDITRTQAHQKKRLK 274
L++ K + ++ ++L + + D+ + + + K
Sbjct: 235 LYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVETDEDKKSRIEK 294
Query: 275 KLEDQKASLERYITEFEGF----TDQYP---EEVVVAGILSISYGNVMEMLYAGMNDDFK 327
KL DQ L+ + EGF +D P +E+ ++G + + YGN LY + +
Sbjct: 295 KLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENILR 354
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEF 382
P + + ++ D+ G + GV G L+ GL KFK F EFIGEF
Sbjct: 355 DTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEF 414
Query: 383 NLPVS----PLYHIANTMY-KIRKQLKNK 406
++ V LY A + KIR + NK
Sbjct: 415 DIVVDNGIYTLYKKAFPQFKKIRNAIMNK 443
>ref|YP_416707.1| methicillin resistance factor protein [Staphylococcus aureus RF122]
sp|Q2YXZ4|FEMB_STAAB Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
emb|CAI80919.1| methicillin resistance factor protein [Staphylococcus aureus RF122]
Length = 419
Score = 108 bits (269), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 98/366 (26%), Positives = 164/366 (44%), Gaps = 36/366 (9%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+GI + +V + SL K+ +G + Y RGPVMD+ D LV + +K L Y + + L
Sbjct: 44 LGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCL 103
Query: 107 FIKYDPAILLKQY---ALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L Y + E EK AL + + G G T E S Q R+
Sbjct: 104 YVKLDPYWLYHLYDKDIVPFEGREKNDALVNL--FKSHGYEHHGFTTEYDTSSQVRWMGV 161
Query: 164 IY----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T E L+ F +R I A GVK + + E + F + TE+R +
Sbjct: 162 LNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSK 221
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + TYGDK + LA ++ LD+Y ++ + Q++ + + + + K E++
Sbjct: 222 TDDYFYNFIDTYGDKVLVPLAYID----LDEY---VLKLQQELNDKENRRDQMMAK-ENK 273
Query: 280 KASLERYITEFEGFTDQYPEEVVVAGILS------------ISYGNVMEMLY--AGMNDD 325
+ I E + D E++ A LS + + N E+ Y G ++
Sbjct: 274 SDKQMKKIAELDKQIDHDQHELLNASELSKTDGSILNLASGVYFANAYEVNYFSGGSSEK 333
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ +F Y+++ + + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 334 YNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIG 393
Query: 381 EFNLPV 386
+F P+
Sbjct: 394 DFYKPI 399
>ref|YP_253581.1| FmhC protein [Staphylococcus haemolyticus JCSC1435]
dbj|BAE04975.1| FmhC protein [Staphylococcus haemolyticus JCSC1435]
Length = 409
Score = 108 bits (269), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 89/335 (26%), Positives = 154/335 (45%), Gaps = 18/335 (5%)
Query: 73 IYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLAL 132
Y RGPVMD+ + LV F K L Y ++ +FI DP +L + E E
Sbjct: 68 FYTHRGPVMDFTNLALVEFFFKKLTHYVSMRRGVFILVDPYVLENIRSADGEIIEHFNNK 127
Query: 133 AAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRLIKDAKQR 188
K + + G G T + Q R+ + + ++ E Q K TRR I +
Sbjct: 128 QWFKVMNKLGYQHQGFTTGYSAMSQIRWHSILDLKDKSEQQLLKDMSYQTRRNIMKTIEM 187
Query: 189 GVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKL 248
GV+ +S E ++F ++ + E++ + E YF++++ YGDKA + LA +++ + +
Sbjct: 188 GVQIKTLSIKETNRFYRLYHMAEEKHGFHFQEEPYFKQMLEIYGDKACMKLAYIDLNKYI 247
Query: 249 DQYRQQLILINQDIT------RTQAHQKK---RLKKLEDQKASLERYITEFEGFTDQYPE 299
+ +Q+ I + + +T + A+ KK + +L Q SL + I + E
Sbjct: 248 NLLKQRAIELEEKVTEIKQSLKVNANSKKTKTKYHQLNQQLESLNKKIAKTEQLIITDGT 307
Query: 300 EVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGS 359
+ +A L I + M L +G N + +F Y L ++ + A + GI N G+ G
Sbjct: 308 LLDLAAALFIYNNHEMYYLSSGSNPKYNEFMGAYCLQWDMIRYAKEKGIERYNFYGITGD 367
Query: 360 L-----DDGLTKFKANFAPTIEEFIGEFNLPVSPL 389
D G+ +FK F +EE++G F PV+ L
Sbjct: 368 FGEDAEDYGVQQFKKGFNAFVEEYVGNFIKPVNKL 402
>ref|NP_646079.1| FemB protein [Staphylococcus aureus subsp. aureus MW2]
sp|Q8NWU0|FEMB_STAAW Aminoacyltransferase femB (Factor essential for expression of
methicillin resistance B)
dbj|BAB95127.1| FemB protein [Staphylococcus aureus subsp. aureus MW2]
Length = 419
Score = 107 bits (268), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 98/366 (26%), Positives = 163/366 (44%), Gaps = 36/366 (9%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL 106
+GI + +V + SL K+ +G + Y RGPVMD+ D LV + +K L Y + + L
Sbjct: 44 LGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCL 103
Query: 107 FIKYDPAILLKQY---ALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQAN 163
++K DP L Y + E EK AL + + G G T E S Q R+
Sbjct: 104 YVKLDPYWLYHLYDKDIVPFEGREKNDALVNL--FKSHGYEHHGFTTEYDTSSQVRWMGV 161
Query: 164 IY----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ T E L+ F +R I A GVK + E + F + TE+R +
Sbjct: 162 LNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLESDEFNLFLDLYRETEERAGFVSK 221
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
+ YF + TYGDK + LA ++ LD+Y ++ + Q++ + + + + K E++
Sbjct: 222 TDDYFYNFIDTYGDKVLVPLAYID----LDEY---VLKLQQELNDKENRRDQMMAK-ENK 273
Query: 280 KASLERYITEFEGFTDQYPEEVVVAGILS------------ISYGNVMEMLY--AGMNDD 325
+ I E + D E++ A LS + + N E+ Y G ++
Sbjct: 274 SDKQMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEK 333
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIG 380
+ +F Y+++ + + +G N G+ G S D G+ +FK F IEE IG
Sbjct: 334 YNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIG 393
Query: 381 EFNLPV 386
+F P+
Sbjct: 394 DFYKPI 399
>ref|YP_817824.1| Peptidoglycan interpeptide bridge formation enzyme [Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293]
gb|ABJ61451.1| Peptidoglycan interpeptide bridge formation enzyme [Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293]
Length = 417
Score = 107 bits (268), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 95/402 (23%), Positives = 186/402 (46%), Gaps = 31/402 (7%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
+++EE+ F K+ + LQ + A++ K ++ +GI ++K VA+ ++ + + +G
Sbjct: 8 LTKEEYTEFEKQSSVGTFLQSGEQAELLQKRGYKIWLLGIKADDKVVAAALVMREKVHMG 67
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA-----LGQE 124
I I RGP++D+ + +L+AF M + + K L+I+ P + LK LG+E
Sbjct: 68 -YIFSIDRGPLLDFENHELLAFFMSNFVKFSRENKGLYIEVRPNVTLKMTNNHGDLLGEE 126
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHTR 179
I+ +++ G + P ++ + + ++++ + K +
Sbjct: 127 N------TVFIEEMKKLGFTHLPFVDGFTTAGSPEWEYIKDLSELTDEKSVRASYNKKAQ 180
Query: 180 RLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHL 239
+K Q G++ ++++ +L F ++ T R + +N ++Q + YGD A
Sbjct: 181 YYLKKNAQFGIRLRQLTRDDLPDFKELTQKTADRLHYKDKNLNFYQTVYDVYGDDATFVF 240
Query: 240 AKVNIP-------QKLDQYRQQLILINQDITR--TQAHQKKRLKKLEDQKASLERYITEF 290
A++N +K+ + +L INQ I + T K++ + +DQK + I +
Sbjct: 241 AELNFDNYIKEENEKISELDAKLAKINQKIEKYPTNDKFKRQYAEFDDQKNQHSKRILKA 300
Query: 291 EGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
E + + VVVAG L I M LY+G +++ +Y Y + + A Q G+
Sbjct: 301 EQQKEAAGKSTVVVAGALFIQQPQEMNYLYSGTYEEYMDYYGPYQIQDVMINKAVQAGLK 360
Query: 350 WANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
N G+ G D DG+ FK F + +G F +PV+P
Sbjct: 361 RYNFYGIAGKFDGSDGVLGFKTTFEGQARQLVGNFMMPVNPF 402
>ref|ZP_02951847.1| FemAB family protein [Clostridium perfringens D str. JGS1721]
gb|EDT73306.1| FemAB family protein [Clostridium perfringens D str. JGS1721]
Length = 445
Score = 107 bits (267), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 117/451 (25%), Positives = 202/451 (44%), Gaps = 60/451 (13%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ-VASLSLLIKL 65
Y + I+ E D F + ++ + Q S WA++K W+ + I Y + V + ++L++
Sbjct: 2 YKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
P + + + YIPR DY ++ L+ + L+++ K FI DP I LK E
Sbjct: 62 APYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLK------E 115
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF-----------QANIYTQENLEMQ 173
EE IKN ++ + + + ++IQP F + NI ++ + +
Sbjct: 116 NEEALSEGTEIKNFLKS-LGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMNI--KKAVFKK 172
Query: 174 FPKHTRRLIKDAKQRG--VKTY---RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLM 228
F TR IK A++RG V+ Y +++ L +F +I+ T KR N +R+ YF+ ++
Sbjct: 173 FSSKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMI 232
Query: 229 TTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITR---------------TQAHQKKRL 273
L++ K + ++ ++L + T+ T +K R+
Sbjct: 233 DYLYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDAETDEDKKSRI 292
Query: 274 -KKLEDQKASLERYITEFEGF----TDQYP---EEVVVAGILSISYGNVMEMLYAGMNDD 325
KKL DQ L+ + EGF +D P +E+ ++G + + YGN LY +
Sbjct: 293 EKKLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENI 352
Query: 326 FKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIG 380
+ P + + ++ D+ G + GV G L+ GL KFK F EFIG
Sbjct: 353 LRDTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIG 412
Query: 381 EFNLPVS----PLYHIANTMY-KIRKQLKNK 406
EF++ V LY A + KIR + NK
Sbjct: 413 EFDIVVDNGIYTLYKKAFPQFKKIRNAIMNK 443
>ref|ZP_02634418.1| FemAB family protein [Clostridium perfringens B str. ATCC 3626]
gb|EDT25271.1| FemAB family protein [Clostridium perfringens B str. ATCC 3626]
Length = 445
Score = 107 bits (267), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 117/449 (26%), Positives = 202/449 (44%), Gaps = 56/449 (12%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ-VASLSLLIKL 65
Y + I+ E D F + ++ + Q S WA++K W+ + I Y + V + ++L++
Sbjct: 2 YKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
P + + + YIPR DY ++ L+ + L+++ K FI DP I LK E
Sbjct: 62 APYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLK------E 115
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQEN-------LEMQFP 175
EE IKN ++ + + + ++IQP F+ + T+ N + +F
Sbjct: 116 NEEALSEGTEIKNFLKS-LGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFS 174
Query: 176 KHTRRLIKDAKQRG--VKTY---RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTT 230
TR IK A++RG V+ Y +++ L +F +I+ T KR N +R+ YF+ ++
Sbjct: 175 SKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDY 234
Query: 231 YGDKAYLHLAKVNIPQKLDQYRQQLILINQDITR---------------TQAHQKKRL-K 274
L++ K + ++ ++L + T+ T +K R+ K
Sbjct: 235 LYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDAETDEDKKSRIEK 294
Query: 275 KLEDQKASLERYITEFEGF----TDQYP---EEVVVAGILSISYGNVMEMLYAGMNDDFK 327
KL DQ L+ + EGF +D P +EV ++G + + YGN LY + +
Sbjct: 295 KLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEVYLSGSIYLYYGNKAWYLYGASENILR 354
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEF 382
P + + ++ D+ G + GV G L+ GL KFK F EFIGEF
Sbjct: 355 DTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEF 414
Query: 383 NLPVS----PLYHIANTMY-KIRKQLKNK 406
++ + LY A + KIR + NK
Sbjct: 415 DIVIDNGIYTLYKKAFPQFKKIRNAIMNK 443
>ref|YP_696770.1| FemAB family protein [Clostridium perfringens ATCC 13124]
ref|YP_699368.1| FemAB family protein [Clostridium perfringens SM101]
ref|ZP_02641343.1| FemAB family protein [Clostridium perfringens NCTC 8239]
gb|ABG83450.1| FemAB family protein [Clostridium perfringens ATCC 13124]
gb|ABG87847.1| FemAB family protein [Clostridium perfringens SM101]
gb|EDT79830.1| FemAB family protein [Clostridium perfringens NCTC 8239]
Length = 445
Score = 107 bits (267), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 117/449 (26%), Positives = 202/449 (44%), Gaps = 56/449 (12%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ-VASLSLLIKL 65
Y + I+ E D F + ++ + Q S WA++K W+ + I Y + V + ++L++
Sbjct: 2 YKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
P + + + YIPR DY ++ L+ + L+++ K FI DP I LK E
Sbjct: 62 APYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLK------E 115
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQEN-------LEMQFP 175
EE IKN ++ + + + ++IQP F+ + T+ N + +F
Sbjct: 116 NEEALSEGTEIKNFLKS-LGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFS 174
Query: 176 KHTRRLIKDAKQRG--VKTY---RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTT 230
TR IK A++RG V+ Y +++ L +F +I+ T KR N +R+ YF+ ++
Sbjct: 175 SKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDY 234
Query: 231 YGDKAYLHLAKVNIPQKLDQYRQQLILINQDITR---------------TQAHQKKRL-K 274
L++ K + ++ ++L + T+ T +K R+ K
Sbjct: 235 LYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDAETDEDKKSRIEK 294
Query: 275 KLEDQKASLERYITEFEGF----TDQYP---EEVVVAGILSISYGNVMEMLYAGMNDDFK 327
KL DQ L+ + EGF +D P +E+ ++G + + YGN LY + +
Sbjct: 295 KLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENILR 354
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEF 382
P + + ++ D+ G + GV G L+ GL KFK F EFIGEF
Sbjct: 355 DTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEF 414
Query: 383 NLPVS----PLYHIANTMY-KIRKQLKNK 406
++ V LY A + KIR + NK
Sbjct: 415 DIVVDNGIYTLYKKAFPQFKKIRNAIMNK 443
>ref|ZP_02638497.1| FemAB family protein [Clostridium perfringens CPE str. F4969]
gb|EDT27730.1| FemAB family protein [Clostridium perfringens CPE str. F4969]
Length = 445
Score = 106 bits (265), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 116/449 (25%), Positives = 202/449 (44%), Gaps = 56/449 (12%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ-VASLSLLIKL 65
Y + I+ E D F + ++ + Q S WA++K W+ + I Y + V + ++L++
Sbjct: 2 YKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
P + + + YIPR DY ++ L+ + L+++ K FI DP I LK E
Sbjct: 62 APYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLK------E 115
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQEN-------LEMQFP 175
EE IKN ++ + + + ++IQP F+ + T+ N + +F
Sbjct: 116 NEEALSEGTEIKNFLKS-LGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFS 174
Query: 176 KHTRRLIKDAKQRG--VKTY---RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTT 230
TR IK A++RG V+ Y +++ L +F +I+ T KR N +R+ YF+ ++
Sbjct: 175 SKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDY 234
Query: 231 YGDKAYLHLAKVNIPQKLDQYRQQLILINQDITR---------------TQAHQKKRL-K 274
L++ K + ++ ++L + T+ T +K R+ K
Sbjct: 235 LYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDAETDEDKKSRIEK 294
Query: 275 KLEDQKASLERYITEFEGF----TDQYP---EEVVVAGILSISYGNVMEMLYAGMNDDFK 327
KL DQ L+ + EGF +D P +E+ ++G + + YGN LY + +
Sbjct: 295 KLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENILR 354
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEF 382
P + + ++ D+ G + GV G L+ GL KFK F EFIGEF
Sbjct: 355 DTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEF 414
Query: 383 NLPVS----PLYHIANTMY-KIRKQLKNK 406
++ + LY A + KIR + NK
Sbjct: 415 DIVIDNGIYTLYKKAFPQFKKIRNAIMNK 443
>ref|ZP_02631903.1| FemAB family protein [Clostridium perfringens E str. JGS1987]
gb|EDT15291.1| FemAB family protein [Clostridium perfringens E str. JGS1987]
Length = 445
Score = 106 bits (265), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 116/449 (25%), Positives = 202/449 (44%), Gaps = 56/449 (12%)
Query: 7 YAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ-VASLSLLIKL 65
Y + I+ E D F + ++ + Q S WA++K W+ + I Y + V + ++L++
Sbjct: 2 YKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRK 61
Query: 66 LP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
P + + + YIPR DY ++ L+ + L+++ K FI DP I LK E
Sbjct: 62 APYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLK------E 115
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQEN-------LEMQFP 175
EE IKN ++ + + + ++IQP F+ + T+ N + +F
Sbjct: 116 NEEALSEGTEIKNFLKS-LGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFS 174
Query: 176 KHTRRLIKDAKQRG--VKTY---RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTT 230
TR IK A++RG V+ Y +++ L +F +I+ T KR N +R+ YF+ ++
Sbjct: 175 SKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDY 234
Query: 231 YGDKAYLHLAKVNIPQKLDQYRQQLILINQDITR---------------TQAHQKKRL-K 274
L++ K + ++ ++L + T+ T +K R+ K
Sbjct: 235 LYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDAETDEDKKSRVEK 294
Query: 275 KLEDQKASLERYITEFEGF----TDQYP---EEVVVAGILSISYGNVMEMLYAGMNDDFK 327
KL DQ L+ + EGF +D P +E+ ++G + + YGN LY + +
Sbjct: 295 KLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENILR 354
Query: 328 KFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEF 382
P + + ++ D+ G + GV G L+ GL KFK F EFIGEF
Sbjct: 355 DTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEF 414
Query: 383 NLPVS----PLYHIANTMY-KIRKQLKNK 406
++ + LY A + KIR + NK
Sbjct: 415 DIVIDNGIYTLYKKAFPQFKKIRNAIMNK 443
>ref|YP_431233.1| Methicillin resistance protein [Moorella thermoacetica ATCC 39073]
gb|ABC20690.1| Methicillin resistance protein [Moorella thermoacetica ATCC 39073]
Length = 363
Score = 104 bits (259), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 103/395 (26%), Positives = 166/395 (42%), Gaps = 81/395 (20%)
Query: 10 IGISEEEH-DSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLL 66
IG EE+ D+FV H + LQ W ++K WQ R+ + +E + +A+ SLL + L
Sbjct: 8 IGPEEEKRFDAFVAGHPKGHFLQSYGWGEVKASTGWQPLRLVLEEEGRIIAAASLLKRRL 67
Query: 67 P-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
P + ++I+Y PRGPV+D+ D DL + + + + + A+ +K DP I A+ +
Sbjct: 68 PYINKAILYAPRGPVVDFHDPDLFSEILAAISRVARQEGAILLKIDPDIPESDRAVKELL 127
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQ-ENLEMQFPKHTRRLI 182
+EK LAA TG D +QPR F+ +I E L TR I
Sbjct: 128 QEKGFRLAARG---------TGF-----DGVQPRHVFRLDITPPLEELLANMHSKTRYNI 173
Query: 183 KDAKQRGVKTYR-VSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
+ A+++GV + +L F +I+ T R + +R+ YF+ + ++ Y L
Sbjct: 174 RLAEKKGVVIKEDCTLEDLPVFYEILKETTLRDHFLVRSYNYFETMWREMVERGYAKL-- 231
Query: 242 VNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV 301
F Y E
Sbjct: 232 ---------------------------------------------------FLALYQGEA 240
Query: 302 VVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD 361
+ AG L+ G+ LY ++ + P YLL + + A + G + GV G LD
Sbjct: 241 I-AGTLAFIMGDKAWYLYGASSNRHRNVMPNYLLQWTMIRWAKEQGCTMYDFRGVPGDLD 299
Query: 362 D-----GLTKFKANFAPTIEEFIGEFNLPVSPLYH 391
+ GL +FK F EF+GE++L SPL++
Sbjct: 300 ENNPLYGLYRFKKGFNGVFTEFVGEYDLVYSPLFY 334
>ref|NP_765544.1| fmhA protein [Staphylococcus epidermidis ATCC 12228]
gb|AAO05630.1|AE016750_235 fmhA protein [Staphylococcus epidermidis ATCC 12228]
Length = 415
Score = 103 bits (258), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 109/419 (26%), Positives = 184/419 (43%), Gaps = 30/419 (7%)
Query: 10 IGISEEEHDSFVKE---HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLL 66
+ ++ EE + F E H S + ++ +K K +G+ +++ V + LL +
Sbjct: 4 VNLTSEEFEQFTSENFSHYTQSSIHYNNRSKTKGDVH--LVGVKDDQEDVIAACLLTEAR 61
Query: 67 PLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEE 125
L Y RGPVM++ + LV F K+L Y K L++ DP +L E
Sbjct: 62 SLKFFKYFYTHRGPVMNFNNLVLVRFFFKSLTAYLKKHNCLYVLVDPYVLENLRQPNGEI 121
Query: 126 EEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRL 181
E A IK ++E G G T+ Q R+ + + ++ E Q K TRR
Sbjct: 122 IESFDNRALIKTMEELGYKHQGYTVGYDTMSQIRWLSVLNLKDKSEDQLLKEMDYQTRRN 181
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
IK + GVK + + F ++ + E++ R E YF ++ TY D A L LA
Sbjct: 182 IKKTYEMGVKVKTLPIEKTDTFFELFKMAEEKHGFKFREEPYFVEMQKTYEDHAMLKLAY 241
Query: 242 VNIPQKLDQYRQQLILINQ---DITRT---QAHQKKRLKKLEDQKASLERYITEFEGFTD 295
+++ LD + + +NQ D+ +T + KK K K + + +
Sbjct: 242 IDLQDYLDTLQTKHQNLNQQLKDVEKTLEENPNSKKNKTKHTQVKQQFDSNARKIRQTKE 301
Query: 296 QYPEE---VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWAN 352
+ EE + +A L I + + L +G N + + Y L ++ Q A + I N
Sbjct: 302 KIAEEGQVLHLAAALYIYNDHEVYYLSSGSNPKYNAYMGAYRLQWDMIQFAKEHNIDRYN 361
Query: 353 MGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNK 406
GV G D G+ KFK F I E+IG+F P+ PL+ YK++++L+++
Sbjct: 362 FYGVTGDFSENAEDAGVQKFKEGFNAKIYEYIGDFIKPIKPLF------YKVKQELESR 414
>ref|YP_252557.1| fmhA protein / lysostaphin immunity factor [Staphylococcus
haemolyticus JCSC1435]
dbj|BAE03951.1| fmhA protein / lysostaphin immunity factor [Staphylococcus
haemolyticus JCSC1435]
Length = 414
Score = 102 bits (255), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 99/379 (26%), Positives = 170/379 (44%), Gaps = 25/379 (6%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKA 105
+G+ + V + +L+ + L Y RGPVMDY + +LV F K+L Y K
Sbjct: 42 VGVKDDSDNVIAATLMTEARALKVFKYFYTHRGPVMDYSNIELVHFFFKSLTSYLKKHNC 101
Query: 106 LFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIY 165
L++ DP IL E E A IK L++ G G T+ + Q R+ + +
Sbjct: 102 LYVLVDPYILENLRNADGEILESYDNRAVIKTLEDLGYKHQGWTVGYSTMSQIRWLSVLD 161
Query: 166 TQENLEMQFPK----HTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
++ E Q K TRR IK + GVK + E F ++ + E++ R++
Sbjct: 162 LKDKSEDQLLKEMDYQTRRNIKKTYEMGVKVRTLPMDETDTFFELFQMAEEKHGFKFRDK 221
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIP-------QKLDQYRQQLILINQDITRTQAHQKKRLK 274
YF ++ TY D A L LA +++ QK D +QL ++ + +K + K
Sbjct: 222 PYFYEMQKTYKDHAMLKLAYIDLKDYLSTLQQKHDSLIEQLAEVDAVLEENPNSKKNKNK 281
Query: 275 K--LEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQ 332
+ ++ Q S ER + E + + E + +A L + + + L +G N + +
Sbjct: 282 RTQIQQQVDSNERKLNETKNKIAEEGETLNLAAALYLYNEHEVYYLSSGSNPKYNAYMGA 341
Query: 333 YLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVS 387
Y L ++ + A + + N G+ G D G+ +FK F + E+IG+F P+
Sbjct: 342 YRLQWDMIKFAKEHNVDRYNFYGITGDFSEDAEDYGVQQFKKGFNANVYEYIGDFIKPIH 401
Query: 388 PLYHIANTMYKIRKQLKNK 406
PL YK+++ L+ K
Sbjct: 402 PL------AYKVKQLLERK 414
>ref|YP_300577.1| fmhA protein [Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305]
dbj|BAE17632.1| fmhA protein [Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305]
Length = 410
Score = 102 bits (254), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 97/413 (23%), Positives = 180/413 (43%), Gaps = 28/413 (6%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
+ ++ EE +F + H ++ + Q+ +G+ + +V + + + L
Sbjct: 4 VNLTPEEFQTFTQNHFSHYTQSRVNY---EAQYNAHLLGVKDDNDEVIAAGMFTEARALK 60
Query: 70 R-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
Y RGP++DY + LV F L Y K L++ DP IL E ++
Sbjct: 61 FFKYFYSQRGPILDYTNLSLVDFYFSELTKYLKQHNCLYVLLDPYILENLRNADGEIKKS 120
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRRLIKD 184
I L++ G G + + + Q R+ + + ++ E Q K TRR IK
Sbjct: 121 YDNRMLISTLEKLGYKHQGYPVGYSKTSQIRWLSVLDLKDKSEQQLLKEMDYQTRRNIKR 180
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
++ GVK ++ E +F K+ + E++ S R+E YF++L Y A + LA +++
Sbjct: 181 TEEMGVKVRQLPIEETDRFFKLFKMAEEKHGFSFRDEPYFEQLQKDYQGFASIQLAYIDL 240
Query: 245 PQKLDQYRQQLILINQDITRTQA---------HQKKRLKKLEDQKASLERYITEFEGFTD 295
+ ++ +Q+L +N + +A QK + +L Q S +R I +
Sbjct: 241 SEYVNGLKQKLDTLNHQMKDVEAALQESPNSKKQKTKQTQLNQQIVSTQRKIDDTNKTIT 300
Query: 296 QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+ +A + I + L +G N D+ + Y L + + A I N G
Sbjct: 301 TDGPVLDLAAAIYIYNDYEVYYLSSGSNPDYNAYMGAYKLQWEMIKFAKNHNIDRYNFYG 360
Query: 356 VEG-----SLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQL 403
+ G ++D G+ +FK F +EE+IG+F P+ PL +YK+ K++
Sbjct: 361 ITGDFSEDAIDYGVQQFKKGFNADVEEYIGDFVKPIKPL------LYKLGKRI 407
>ref|ZP_00121082.1| COG2348: Uncharacterized protein involved in methicillin resistance
[Bifidobacterium longum DJO10A]
Length = 436
Score = 102 bits (253), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 95/422 (22%), Positives = 181/422 (42%), Gaps = 38/422 (9%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKN-QWQNERIGIYKEEKQVASLSLLIKLLPLG- 69
I+ E D+F Q S Q S A + + +G+ + +K +A+ ++ G
Sbjct: 16 ITPAELDAFSAAQVQGSFQQTSQMAAMGAFNGPVDYVGVKRGDKLIAACYVVYTRSRFGL 75
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
++ GP+ DY + +V + L+ K A+ + PA + + + L + P
Sbjct: 76 EGSVWC--GPLCDYDNPQVVEAMTEALRRSAKAHHAISVSCWPAAVYRLHDLDGKPTSDP 133
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHTRRLIKD 184
+ N+ G G T+ +S+ R+ I+ ++ L F K+ R+ I+
Sbjct: 134 -DTTMMDNMARFGWKHGGFTVGY-ESVVNRWNFVKGLDGIHNEKELLASFSKYRRKNIRI 191
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
A+ G++ R+ + EL F K+ ++ R+ R+ AY+++L T+GD + + +
Sbjct: 192 AQDSGLRVRRLERGELSTFVKLCDMSAARQGFKSRDLAYYERLFDTFGDLIEFKVVETHF 251
Query: 245 PQKLDQYRQQLILINQD-------ITRTQ--------------AHQKKRLKKLEDQKASL 283
+ LD + +L ++D + R Q A +KR+ + + A+L
Sbjct: 252 DEYLDTLQSKLNAASKDKRNLERLLQRAQQQPEGTAKKGASDPATLEKRIATADKKIAAL 311
Query: 284 ERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDA 343
E+ I E G + V + + N + L +G +D F +YP L++ D
Sbjct: 312 EKTIGEVNGIIASDGPVIPVEAGVYFWHPNEVVCLSSGEDDRFMDYYPSSLIHFEAMLDC 371
Query: 344 YQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMY 397
G+ N G+ G D G+ +FK F +EE G+F LPV L + ++ +
Sbjct: 372 IARGVERFNFYGISGIFDANDPSYGVWQFKTRFGGFVEELPGKFTLPVDGLRFGVSEAAH 431
Query: 398 KI 399
K+
Sbjct: 432 KL 433
>ref|NP_695487.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium longum
NCC2705]
gb|AAN24123.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium longum
NCC2705]
Length = 436
Score = 101 bits (252), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 95/422 (22%), Positives = 181/422 (42%), Gaps = 38/422 (9%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKN-QWQNERIGIYKEEKQVASLSLLIKLLPLG- 69
I+ E D+F Q S Q S A + + +G+ + +K +A+ ++ G
Sbjct: 16 ITPAELDAFSAAQVQGSFQQTSQMAAMGAFNGPVDYVGVKRGDKLIAACYVVYTRSRFGL 75
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
++ GP+ DY + +V + L+ K A+ + PA + + + L + P
Sbjct: 76 EGSVWC--GPLCDYDNPQVVEAMTEALRRSAKAHHAISVSCWPAAVYRLHDLDGKPTSDP 133
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHTRRLIKD 184
+ N+ G G T+ +S+ R+ I+ ++ L F K+ R+ I+
Sbjct: 134 -DTTMMDNMARFGWKHGGFTVGY-ESVVNRWNFVKGLDCIHNEKELLASFSKYRRKNIRI 191
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
A+ G++ R+ + EL F K+ ++ R+ R+ AY+++L T+GD + + +
Sbjct: 192 AQDSGLRVRRLERGELSTFVKLCDMSAARQGFKSRDLAYYERLFDTFGDLIEFKVVETHF 251
Query: 245 PQKLDQYRQQLILINQD-------ITRTQ--------------AHQKKRLKKLEDQKASL 283
+ LD + +L ++D + R Q A +KR+ + + A+L
Sbjct: 252 DEYLDTLQSKLNAASKDKRNLERLLQRAQQQPEGTAKKGASDPATLEKRIATADKKIAAL 311
Query: 284 ERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDA 343
E+ I E G + V + + N + L +G +D F +YP L++ D
Sbjct: 312 EKTIGEVNGIIASDGPVIPVEAGVYFWHPNEVVCLSSGEDDRFMDYYPSSLIHFEAMLDC 371
Query: 344 YQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMY 397
G+ N G+ G D G+ +FK F +EE G+F LPV L + ++ +
Sbjct: 372 IARGVERFNFYGISGIFDANDPSYGVWQFKTRFGGFVEELPGKFTLPVDGLRFGVSEAAH 431
Query: 398 KI 399
K+
Sbjct: 432 KL 433
>dbj|BAA21486.1| epr [Staphylococcus capitis]
Length = 413
Score = 100 bits (249), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 103/420 (24%), Positives = 181/420 (43%), Gaps = 36/420 (8%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNE--RIGIYKEEKQVASLSLLIKLLP 67
+ +S+ E +FV H Q + +N++QN+ +G+ V + LL +
Sbjct: 4 VQLSKTEFQNFVNSHFS-HYTQSNQHFDYRNKFQNDVHLVGVKDNVGTVIAACLLTEAQA 62
Query: 68 LGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLK----QYALG 122
L Y RGPV+D+ + +LV F K L Y K + LF+ DP L Q +
Sbjct: 63 LKVFKYFYTHRGPVLDFKNFELVRFFYKNLTRYLKKNRGLFVLTDPYTLENIRNAQGEIL 122
Query: 123 QEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI-YTQENLEM---QFPKHT 178
+ +PL IK L+ G G ++ + + Q R+ + + +N +M + T
Sbjct: 123 TSYDNRPL----IKTLKNIGYKHQGYSIGYSQTSQIRWLSVLDLNNKNTDMLLSEMDYQT 178
Query: 179 RRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLH 238
RR IK + V+ +S E +F K+ + E++ RN+ YF+K+ Y D + L
Sbjct: 179 RRNIKKTYEMNVQVRTLSIEETSRFFKLFKMAEEKHGFKFRNQDYFEKMQKIYNDNSMLK 238
Query: 239 LAKVNIPQKLDQYRQQLILINQD---------ITRTQAHQKKRLKKLEDQKASLERYITE 289
LA +N+ L++ ++ +N+ K + ++ Q ++ R I E
Sbjct: 239 LAYINLSDLLEKQNNKITQLNKQYEEIINALKANPNSKKNKNKANQINQQISAQNRKINE 298
Query: 290 FEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
+ + + +A I + + L +G N + + Y L + + A Q+ I
Sbjct: 299 TKELIKTDGKIIDLAAAFYIYNNDEVYYLSSGSNPKYNAYMGAYRLQWEMIKFAKQNNIP 358
Query: 350 WANMGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLK 404
N G+ G D G+ +FK F +EE+IG+F P+ P +YKI LK
Sbjct: 359 RYNFYGITGDFSETAEDYGVQRFKEGFNAYVEEYIGDFIKPLRPF------IYKIYTLLK 412
>ref|ZP_01371899.1| Methicillin resistance protein [Desulfitobacterium hafniense DCB-2]
gb|EAT50641.1| Methicillin resistance protein [Desulfitobacterium hafniense DCB-2]
Length = 360
Score = 100 bits (248), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 99/403 (24%), Positives = 172/403 (42%), Gaps = 80/403 (19%)
Query: 13 SEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPL-G 69
++E D F+ H + VLQ W ++K++ W+ R+ + + VA++S+L + +P+ G
Sbjct: 12 AKERFDQFMARHAKGHVLQTWGWGELKSKTGWKPWRLVLEDRGEIVAAISILERKIPVVG 71
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
I Y RGPV+D+ D +L + +K K + A+F+K DP I ++ E
Sbjct: 72 IPIFYASRGPVLDWTDHELFDALLVEIKKLAKKRGAIFLKIDPDI-----PSADQDLEGY 126
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYT-QENLEMQFPKHTRRLIKDAK 186
L ++ + TG E +QP+ F+ +I +E L Q + TR +K A
Sbjct: 127 LKSRGFRSAE------TGKGFE---GVQPKYVFRLDISPDEETLMAQMHQKTRYNVKLAT 177
Query: 187 QRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ 246
++GV ++ +L F +++ T +R +RN +YF+ + LH A +
Sbjct: 178 KKGVAIRVGTKEDLPAFYRVLKETTERDKFLVRNYSYFEDMYDE------LHAAGMA--- 228
Query: 247 KLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGI 306
E +I E+EG ++AG
Sbjct: 229 -------------------------------------ELFIAEYEG--------QIIAGT 243
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD---- 362
L++ G LY ++ + P YL+ + + A G + GV G L +
Sbjct: 244 LALIIGEKAWYLYGASSNSHRNVMPNYLIQWEMIRWAKAKGCTLYDFRGVPGHLTEDNPL 303
Query: 363 -GLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQL 403
GL +FK F EFIGE++L P +Y + NT+ + L
Sbjct: 304 YGLYRFKKGFNGEYTEFIGEWDLVYRPVVYFLWNTLEPVYSDL 346
>ref|YP_521176.1| hypothetical protein DSY4943 [Desulfitobacterium hafniense Y51]
dbj|BAE86732.1| hypothetical protein [Desulfitobacterium hafniense Y51]
Length = 360
Score = 99.4 bits (246), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 98/403 (24%), Positives = 172/403 (42%), Gaps = 80/403 (19%)
Query: 13 SEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPL-G 69
++E D F+ H + VLQ W ++K++ W+ R+ + + VA++S+L + +P+ G
Sbjct: 12 AKERFDQFMARHAKGHVLQTWGWGELKSKTGWKPWRLVLEDRGEIVAAISILERKIPVVG 71
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
I Y RGPV+D+ D +L + +K K + A+F+K DP I ++ E
Sbjct: 72 IPIFYASRGPVLDWTDHELFDALLVEIKKLAKKRGAIFLKIDPDI-----PSADQDLEGY 126
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYT-QENLEMQFPKHTRRLIKDAK 186
L ++ + TG E +QP+ F+ +I +E L Q + TR +K A
Sbjct: 127 LKSRGFRSAE------TGKGFE---GVQPKYVFRLDISPDEETLMAQMHQKTRYNVKLAT 177
Query: 187 QRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ 246
++GV ++ +L F +++ T +R +RN +YF+ + LH A +
Sbjct: 178 KKGVAIRVGTKEDLPAFYRVLKETTERDKFLVRNYSYFEDMYDE------LHAAGMA--- 228
Query: 247 KLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGI 306
E +I E+EG ++AG
Sbjct: 229 -------------------------------------ELFIAEYEG--------QIIAGT 243
Query: 307 LSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD---- 362
L++ G LY ++ + P YL+ + + A G + GV G L +
Sbjct: 244 LALIIGEKAWYLYGASSNSHRNVMPNYLIQWEMIRWAKAKGCTLYDFRGVPGHLTEDNPL 303
Query: 363 -GLTKFKANFAPTIEEFIGEFNLPVSP-LYHIANTMYKIRKQL 403
GL +FK F EF+GE++L P +Y + NT+ + L
Sbjct: 304 YGLYRFKKGFNGEYTEFVGEWDLVYRPVVYFLWNTLEPVYSDL 346
>ref|YP_227596.1| lysostaphin endopeptidase resistance protein [Staphylococcus sciuri
subsp. sciuri]
gb|AAG16879.2| lysostaphin endopeptidase resistance [Staphylococcus sciuri subsp.
sciuri]
Length = 415
Score = 99.4 bits (246), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 101/410 (24%), Positives = 190/410 (46%), Gaps = 26/410 (6%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNER--IGIYKEEKQVASLSLLIKLLP 67
+ +S+EE D F +E+ Q + + +N+ + + +G+ QV + SLL +
Sbjct: 4 LKLSKEEFDKFTQENFS-HYTQSLNHFEYRNEHKKDVHIVGVKNNNGQVIAASLLTEARA 62
Query: 68 LGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY-ALGQE- 124
L Y RGPV+DY +++LV F K L Y K + LF+ DP I+++++ A G+
Sbjct: 63 LRFFKYFYSHRGPVIDYNNKELVNFFFKNLTKYLKKQNCLFVLVDPYIVIQKHTADGKTI 122
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPK----HTRR 180
E + + AI L+ G G ++ Q R+ + + ++ E + K TRR
Sbjct: 123 ESYEHQSFKAI--LESLGYKHQGYSVGYQPMSQIRWLSVLDLKDKSEDELLKEMNYQTRR 180
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
IK ++ V+ ++ +E +F K+ + E++ S R YF+++ Y D + L +A
Sbjct: 181 NIKKTEEMNVQIEDLNINETERFFKLFKMAEEKHGFSFRGLDYFKEMQKIYHDNSMLKIA 240
Query: 241 KVNIPQKL------DQYRQQLILINQDITRTQAHQKKR---LKKLEDQKASLERYITEFE 291
+N+ L D+ + +L+ ++ + + KK+ + L + S + I + +
Sbjct: 241 TINLKDYLKSLELQDEQLKNDVLLAENKLKENPNSKKQKTAINNLLQRLDSSNKKIDKIK 300
Query: 292 GFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWA 351
+ E + +A L I + M L +G N + +F Y L + + + I
Sbjct: 301 RLIETDGEIIDLAAALYIYNNHEMYYLSSGSNPKYNEFMGAYKLQWEMIKFSKTHNIERY 360
Query: 352 NMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTM 396
N GV G D G+ +FK F +EE+IG+F P+ ++ N +
Sbjct: 361 NFYGVTGDFSDTAEDYGVQQFKKGFNANVEEYIGDFIKPIRKNWYFINKL 410
>ref|ZP_02839171.1| Methicillin resistance protein [Arthrobacter chlorophenolicus A6]
gb|EDS60977.1| Methicillin resistance protein [Arthrobacter chlorophenolicus A6]
Length = 437
Score = 99.0 bits (245), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 106/409 (25%), Positives = 176/409 (43%), Gaps = 26/409 (6%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPLG 69
+S++E ++F +H Q S LQ +D+ + + Q E GI + + VA+ L LG
Sbjct: 15 LSDDEFEAFALKHPQNSFLQSADFTRFQRARGQQVELFGIRRNGELVAAGKLNFTTTRLG 74
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
++ +GP+MDY D LV + L+ +KA ++ P LK A ++ E P
Sbjct: 75 YTVCDCAKGPLMDYTDPALVRDVVVLLRKRAAERKAAELRISPN--LKYIARDEDGAEHP 132
Query: 130 LAL---AAIKNLQEAGVHWTGLTMEIADSIQPRFQAN---IYTQENLEMQFPKHTRRLIK 183
+ + L G GL M + + F + I E L M TR+ I+
Sbjct: 133 ETVDNRPLVARLGGLGFRHQGLEMNFVN-VNWMFVKDLQGIADPEELIMGTSYRTRKAIR 191
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLM-TTYGDKAYLHLAKV 242
A++ GV + + L F +S K R Y++ L+ TT + L +AK+
Sbjct: 192 KAEKNGVFLEQATLETLDDFYGALSRAGDEKGFVYREREYYENLLRTTSPEFTKLMMAKI 251
Query: 243 NIP-------QKLDQYRQQLILINQDITRTQAHQK-KRLKKLEDQKASLERYITEFEGFT 294
+IP ++LD + +++ T + +K RLK ++D S ER + + E F
Sbjct: 252 DIPAYRKSITERLDAESATAAELRREVEETGSKKKANRLKVVQDLVDSYERSLKDIERFP 311
Query: 295 DQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMG 354
D VA I + YG+ + + G D+ F LY + A + G N
Sbjct: 312 DSVG-VATVAAIHFVCYGDEVVCVIGGTVQDYIYFNGATSLYWGMMLHALEKGYPRYNFY 370
Query: 355 GVEG-SLDD----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYK 398
G G S D G +FK F + + +G+F +PV AN + +
Sbjct: 371 GTFGISGQDQEGHGGYEFKKGFGGEVVQLVGDFVMPVRAAAFHANRLAR 419
>ref|YP_946784.1| putative FemAB family protein [Arthrobacter aurescens TC1]
gb|ABM09637.1| putative FemAB family protein [Arthrobacter aurescens TC1]
Length = 438
Score = 97.4 bits (241), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 105/405 (25%), Positives = 184/405 (45%), Gaps = 36/405 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPLG 69
+S+ + ++F K H Q S +Q D + + + E G+ + +A+ L+ +G
Sbjct: 6 LSDADFETFAKGHPQGSFIQSMDLTRFQRARGQEVELFGVTRGGSLIAAGKLVYTSNRVG 65
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAI-LLKQYALGQE---- 124
+GP+MDY D +V+F ++ LK + +KKA + P I + + G E
Sbjct: 66 YKTADCAKGPLMDYSDPTVVSFVVEQLKKHAASKKAAELCISPNIRYIARDEEGAEHPEV 125
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF--QAN-IYTQENLEMQFPKHTRRL 181
E+ +PL +K L+ G G M A+ I F Q N I E L M TR+
Sbjct: 126 EDNRPL----LKELEGLGFKHQGFDMNFAN-INWMFIKQLNGIADSEELIMGMNYRTRKA 180
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDK-AYLHLA 240
I+ A++ GV + + L +F +S K + R Y+++L+ D+ L +A
Sbjct: 181 IRKAEKNGVYLEQATLETLDEFYNALSTAGDEKGFTYREREYYEQLLRNTSDEFTKLMMA 240
Query: 241 KVNIP-------QKLDQYRQQLILINQDITRTQAHQK-KRLKKLEDQKASLERYITEFEG 292
K+NIP ++LD + L + +++ T + +K R+K ++D S ER + + E
Sbjct: 241 KINIPEYRASITERLDAESKTLAELKREVEETGSKKKANRVKVVQDLVDSYERSLKDIE- 299
Query: 293 FTDQYPEEVVVAGILSISY---GNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
++P+ V VA + +I + G+ + + G D+ F LY + A +G
Sbjct: 300 ---RFPDSVGVATVAAIHFACSGDELVCVIGGTVQDYIYFNGATSLYWGMMLHALNNGYS 356
Query: 350 WANMGGVEG-----SLDDGLTKFKANFAPTIEEFIGEFNLPVSPL 389
N G G G +FK F + + +G+F PV+PL
Sbjct: 357 RYNFYGTFGIQGQDETGHGGYEFKKGFGGEVVQLVGDFVAPVNPL 401
>ref|ZP_02442075.1| hypothetical protein ANACOL_01364 [Anaerotruncus colihominis DSM
17241]
gb|EDS11986.1| hypothetical protein ANACOL_01364 [Anaerotruncus colihominis DSM
17241]
Length = 349
Score = 96.7 bits (239), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 86/384 (22%), Positives = 152/384 (39%), Gaps = 80/384 (20%)
Query: 16 EHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV-ASLSLLIKLLPL-GRSII 73
E ++FV H Q Q +W K+KN W E + + + ++S+L++ +PL G S +
Sbjct: 11 EFEAFVSAHPQGCFTQSVNWQKVKNNWGYEAVVSRTADGTIQGAVSVLVQKIPLIGTSFL 70
Query: 74 YIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALA 133
Y PRGPV D DR ++A + K +A K DP +L+ + ++ +
Sbjct: 71 YAPRGPVCDPHDRAVLADLKAGVDALAKKYRAHAFKMDPDVLMSDAEFIRIAKD----MG 126
Query: 134 AIKNLQEAGVHWTGLTMEIADSIQPRFQANIY----TQENLEMQFPKHTRRLIKDAKQRG 189
+++ G + IQ RF +Y T++ L + TRR ++ A +
Sbjct: 127 FVQSYGPDGF----------EGIQARFNYRLYLNGRTEDELFANLTQGTRRKVRIAIKND 176
Query: 190 VKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLD 249
V+ V L +F +I+ +T R ++R AYF++++ G+ L++
Sbjct: 177 VQVRPVGPEYLDEFVRIMRVTGARDGFNVRPRAYFERMLDALGEHVRLYM---------- 226
Query: 250 QYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSI 309
GF P V G ++
Sbjct: 227 ------------------------------------------GFYQGTP----VCGAVTT 240
Query: 310 SYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD----GLT 365
+Y +Y ++ + P YL+ + + A Q G + GV G L+ GL
Sbjct: 241 NYAGKCCYVYGASDNVHRDVMPNYLMQWEMIKWAVQTGCEVYDFQGVSGDLEGGHMAGLY 300
Query: 366 KFKANFAPTIEEFIGEFNLPVSPL 389
+FK F ++E GEF+ P+
Sbjct: 301 QFKRGFNGQLDELAGEFDYTYKPI 324
>ref|NP_695488.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium longum
NCC2705]
gb|AAN24124.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium longum
NCC2705]
Length = 422
Score = 96.3 bits (238), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 95/406 (23%), Positives = 178/406 (43%), Gaps = 30/406 (7%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKN-QWQNERIGIYKEEKQVASLSLLIKLLPL 68
+ +++EE D F H Q + Q S +++ Q + KE +++ + +L
Sbjct: 7 VKLTDEEFDDFSARHPQGNFQQTSAMGRLRAAQGIDVEYLALKEGEKIVAAALFETHRSR 66
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLK-----QYALGQ 123
+ I GP+ DY D + + F M LK + K K A ++ P + +L
Sbjct: 67 FSTFAVIHDGPMCDYHDTEALTFFMDALKRHAKAKGASQLEITPESSYRLRDTNGASLPD 126
Query: 124 EEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHT 178
++ P I+ L+ G G T + + PR++ I +++L + K T
Sbjct: 127 DQNGAPDN-KLIEQLEAIGFTHGGFT--VGYTAVPRWRYLKDLTGITDEKSLLKSYDKRT 183
Query: 179 RRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLH 238
+ +K A+ GV +S EL F++I T +R++ R EAYF + +G KA+
Sbjct: 184 QWSVKRAQSMGVHVRELSDDELGVFARIEQQTAERRSFEYRGEAYFHRFKEAFGSKAHFM 243
Query: 239 LAKVNIPQ---KLDQYRQQL-----ILINQDITRTQAHQKKRLKKLEDQKASLERYITEF 290
+A+++I + + R+ L L ++ +++L + A+ E+ + E
Sbjct: 244 VAEIHIDEYVADMTSKREALSAKVAALTAKNAEHPTTKTERQLGEETRNLAAAEKRLNEA 303
Query: 291 EGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLL-YPNVFQDAYQDGII 349
F + + A L + + + L++G + +K FY L+ + + + G+
Sbjct: 304 AEFAKD-GDVLPAAASLFVEHPREVIYLFSGSVEQYKPFYASALIQHDAMLHFCVEHGLS 362
Query: 350 WANMGGVEGSLDD------GLTKFKANFAPTIEEFIGEFNLPVSPL 389
N G++G DD G+ +FK F +EE GEF LPV P+
Sbjct: 363 RYNFYGIDGVFDDPDDEGRGVLEFKQGFNGYVEELPGEFVLPVKPV 408
>ref|ZP_00790183.1| beta-lactam resistance factor [Streptococcus agalactiae 515]
gb|EAO71076.1| beta-lactam resistance factor [Streptococcus agalactiae 515]
Length = 411
Score = 95.1 bits (235), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 102/397 (25%), Positives = 187/397 (47%), Gaps = 25/397 (6%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
+ + GP + + + K L++Y K++ AL + P +++ G+ E +
Sbjct: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFT-GEGEPKGA 121
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRRLIKDA 185
I +L G H GL + +P + N+ T +NL F K R L+K A
Sbjct: 122 PNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
Query: 186 KQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI- 244
G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A +N
Sbjct: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
Query: 245 ---------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD 295
+KL++ L +Q+ T + + ++R +L +Q ASL++ E E F
Sbjct: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEVEPFIQ 299
Query: 296 QYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMG 354
++ ++VV+AG L I L++G +F KFY +L V Q+A + + N
Sbjct: 300 KFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
Query: 355 GVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
>ref|ZP_00787931.1| beta-lactam resistance factor [Streptococcus agalactiae CJB111]
gb|EAO73343.1| beta-lactam resistance factor [Streptococcus agalactiae CJB111]
Length = 411
Score = 95.1 bits (235), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 107/402 (26%), Positives = 188/402 (46%), Gaps = 35/402 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE--EEE 127
+ + GP + + + K L++Y K++ AL +L+K Y QE E
Sbjct: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGAL------ELLIKPYDTYQEFTGEG 116
Query: 128 KPLALAA---IKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRR 180
KP I +L G H GL + +P + N+ T +NL F K R
Sbjct: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K A G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A
Sbjct: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
Query: 241 KVNI----------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEF 290
+N +KL++ L +Q+ T + + ++R +L +Q ASL++ E
Sbjct: 236 TLNFREYDHNLQLNAKKLEEQITVLDNHHQNNTDSAKYHRQR-TELVNQLASLDKRRKEV 294
Query: 291 EGFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
E F ++ ++VV+AG L I L++G +F KFY +L V Q+A +
Sbjct: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
Query: 350 WANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
+ N G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 FYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
>ref|NP_687538.1| beta-lactam resistance factor [Streptococcus agalactiae 2603V/R]
ref|ZP_00780367.1| beta-lactam resistance factor [Streptococcus agalactiae 18RS21]
ref|ZP_00782558.1| beta-lactam resistance factor [Streptococcus agalactiae H36B]
gb|AAM99410.1|AE014215_4 beta-lactam resistance factor [Streptococcus agalactiae 2603V/R]
gb|EAO63025.1| beta-lactam resistance factor [Streptococcus agalactiae 18RS21]
gb|EAO78734.1| beta-lactam resistance factor [Streptococcus agalactiae H36B]
Length = 411
Score = 95.1 bits (235), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 107/402 (26%), Positives = 188/402 (46%), Gaps = 35/402 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE--EEE 127
+ + GP + + + K L++Y K++ AL +L+K Y QE E
Sbjct: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGAL------ELLIKPYDTYQEFTGEG 116
Query: 128 KPLALAA---IKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRR 180
KP I +L G H GL + +P + N+ T +NL F K R
Sbjct: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K A G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A
Sbjct: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
Query: 241 KVNI----------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEF 290
+N +KL++ L +Q+ T + + ++R +L +Q ASL++ E
Sbjct: 236 TLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEV 294
Query: 291 EGFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
E F ++ ++VV+AG L I L++G +F KFY +L V Q+A +
Sbjct: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
Query: 350 WANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
+ N G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 FYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
>ref|YP_041851.1| FemAB family protein [Staphylococcus aureus subsp. aureus MRSA252]
emb|CAG41481.1| FemAB family protein [Staphylococcus aureus subsp. aureus MRSA252]
Length = 416
Score = 95.1 bits (235), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 99/379 (26%), Positives = 165/379 (43%), Gaps = 25/379 (6%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKA 105
+G+ + QV + LL + L Y RGPVMDY ++ LVAF K L Y K +
Sbjct: 42 VGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNC 101
Query: 106 LFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIY 165
L++ DP ++ E + A ++ + G G + Q R+ + +
Sbjct: 102 LYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLD 161
Query: 166 TQENLEMQFPK----HTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
++ E Q K TRR IK GVKT ++ E F + + E++ R
Sbjct: 162 LKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFREL 221
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLD--QYRQQ-----LILINQDITRTQAHQKKRLK 274
YF+++ Y D A L LA +++ + L Q +QQ L + + + + +K + K
Sbjct: 222 PYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTK 281
Query: 275 K--LEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQ 332
+ LE Q S +R I +Q + +A L I + + L +G N + +
Sbjct: 282 RTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGA 341
Query: 333 YLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVS 387
Y L + + A I N G+ G D G+ +FK F +EE+IG+F P+
Sbjct: 342 YHLQWEMIKFAKAHHIDRYNFYGITGDFSESAEDYGVQQFKKGFNAHVEEYIGDFIKPIK 401
Query: 388 PLYHIANTMYKIRKQLKNK 406
P+ +YK++ LK+K
Sbjct: 402 PI------LYKLQTYLKHK 414
>ref|ZP_00785648.1| beta-lactam resistance factor [Streptococcus agalactiae COH1]
gb|EAO75611.1| beta-lactam resistance factor [Streptococcus agalactiae COH1]
Length = 411
Score = 95.1 bits (235), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 102/397 (25%), Positives = 186/397 (46%), Gaps = 25/397 (6%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
+ + GP + + + K L++Y K++ AL + P +++ G+ E +
Sbjct: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFT-GEGEPKGA 121
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRRLIKDA 185
I L G H GL + +P + N+ T +NL F K R L+K A
Sbjct: 122 PNTYLIDGLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
Query: 186 KQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI- 244
G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A +N
Sbjct: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
Query: 245 ---------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD 295
+KL++ L +Q+ T + + ++R +L +Q ASL++ E E F
Sbjct: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEVEPFIQ 299
Query: 296 QYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMG 354
++ ++VV+AG L I L++G +F KFY +L V Q+A + + N
Sbjct: 300 KFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
Query: 355 GVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
>ref|NP_647150.1| fmhA protein [Staphylococcus aureus subsp. aureus MW2]
ref|YP_044414.1| FemAB family protein [Staphylococcus aureus subsp. aureus MSSA476]
ref|YP_187212.1| fmhA protein [Staphylococcus aureus subsp. aureus COL]
ref|YP_494991.1| fmhA protein [Staphylococcus aureus subsp. aureus USA300]
ref|YP_501158.1| fmhA protein, putative [Staphylococcus aureus subsp. aureus NCTC
8325]
ref|YP_001333344.1| methicillin resistance determinant fmhA protein [Staphylococcus
aureus subsp. aureus str. Newman]
ref|YP_001576261.1| FemAB family peptidoglycan biosynthesis protein [Staphylococcus
aureus subsp. aureus USA300_TCH1516]
ref|ZP_02761361.1| FemAB family peptidoglycan biosynthesis protein [Staphylococcus
aureus subsp. aureus USA300_TCH1516]
dbj|BAB96198.1| fmhA protein [Staphylococcus aureus subsp. aureus MW2]
emb|CAG44115.1| FemAB family protein [Staphylococcus aureus subsp. aureus MSSA476]
gb|AAW37234.1| fmhA protein [Staphylococcus aureus subsp. aureus COL]
gb|ABD21500.1| fmhA protein [Staphylococcus aureus subsp. aureus USA300_FPR3757]
gb|ABD31704.1| fmhA protein, putative [Staphylococcus aureus subsp. aureus NCTC
8325]
dbj|BAF68582.1| methicillin resistance determinant fmhA protein [Staphylococcus
aureus subsp. aureus str. Newman]
gb|ABX30382.1| FemAB family peptidoglycan biosynthesis protein [Staphylococcus
aureus subsp. aureus USA300_TCH1516]
Length = 416
Score = 94.7 bits (234), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 100/379 (26%), Positives = 165/379 (43%), Gaps = 25/379 (6%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKA 105
+G+ + QV + LL + L Y RGPVMDY ++ LVAF K L Y K
Sbjct: 42 VGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNC 101
Query: 106 LFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIY 165
L++ DP ++ E + A ++ + + G G + Q R+ + +
Sbjct: 102 LYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLD 161
Query: 166 TQENLEMQFPK----HTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
++ E Q K TRR IK GVKT ++ E F + + E++ R
Sbjct: 162 LKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFREL 221
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLD--QYRQQ-----LILINQDITRTQAHQKKRLK 274
YF+++ Y D A L LA +++ + L Q +QQ L + + + + +K + K
Sbjct: 222 PYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTK 281
Query: 275 K--LEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQ 332
+ LE Q S +R I +Q + +A L I + + L +G N + +
Sbjct: 282 RTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGA 341
Query: 333 YLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIGEFNLPVS 387
Y L + + A I N G+ G S D G+ +FK F +EE+IG+F P+
Sbjct: 342 YHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIK 401
Query: 388 PLYHIANTMYKIRKQLKNK 406
PL +YK++ L +K
Sbjct: 402 PL------LYKVQTYLNHK 414
>ref|NP_372935.1| fmhA protein [Staphylococcus aureus subsp. aureus Mu50]
ref|NP_375522.1| fmhA protein [Staphylococcus aureus subsp. aureus N315]
ref|YP_001247789.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
ref|YP_001317595.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
ref|YP_001442985.1| fmhA protein [Staphylococcus aureus subsp. aureus Mu3]
gb|AAD23960.1|AF106849_1 FmhA [Staphylococcus aureus]
dbj|BAB43501.1| fmhA protein [Staphylococcus aureus subsp. aureus N315]
dbj|BAB58573.1| fmhA protein [Staphylococcus aureus subsp. aureus Mu50]
gb|ABQ50213.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
gb|ABR53308.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
dbj|BAF79278.1| fmhA protein [Staphylococcus aureus subsp. aureus Mu3]
Length = 416
Score = 94.7 bits (234), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 100/379 (26%), Positives = 165/379 (43%), Gaps = 25/379 (6%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKA 105
+G+ + QV + LL + L Y RGPVMDY ++ LVAF K L Y K
Sbjct: 42 VGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNC 101
Query: 106 LFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIY 165
L++ DP ++ E + A ++ + + G G + Q R+ + +
Sbjct: 102 LYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLD 161
Query: 166 TQENLEMQFPK----HTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
++ E Q K TRR IK GVKT ++ E F + + E++ R
Sbjct: 162 LKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFREL 221
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLD--QYRQQ-----LILINQDITRTQAHQKKRLK 274
YF+++ Y D A L LA +++ + L Q +QQ L + + + + +K + K
Sbjct: 222 PYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTK 281
Query: 275 K--LEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQ 332
+ LE Q S +R I +Q + +A L I + + L +G N + +
Sbjct: 282 RTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGA 341
Query: 333 YLLYPNVFQDAYQDGIIWANMGGVEG-----SLDDGLTKFKANFAPTIEEFIGEFNLPVS 387
Y L + + A I N G+ G S D G+ +FK F +EE+IG+F P+
Sbjct: 342 YHLQWEMIKFAKAHHIDRYNFYGITGDYSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIK 401
Query: 388 PLYHIANTMYKIRKQLKNK 406
PL +YK++ L +K
Sbjct: 402 PL------LYKVQTYLNHK 414
>ref|YP_329290.1| beta-lactam resistance factor [Streptococcus agalactiae A909]
gb|ABA46228.1| beta-lactam resistance factor [Streptococcus agalactiae A909]
Length = 411
Score = 94.7 bits (234), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 107/402 (26%), Positives = 188/402 (46%), Gaps = 35/402 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE--EEE 127
+ + GP + + + K L++Y K++ AL +L+K Y QE E
Sbjct: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGAL------ELLIKPYDTYQEFTGEG 116
Query: 128 KPLALAA---IKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRR 180
KP I +L G H GL + +P + N+ T +NL F K R
Sbjct: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGG-KPDWHYVKNLEGITPQNLLKSFSKKGRP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K A G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A
Sbjct: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
Query: 241 KVNI----------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEF 290
+N +KL++ L +Q+ T + + ++R +L +Q ASL++ E
Sbjct: 236 TLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEV 294
Query: 291 EGFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
E F ++ ++VV+AG L I L++G +F KFY +L V Q+A +
Sbjct: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
Query: 350 WANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
+ N G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 FYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
>ref|NP_735018.1| hypothetical protein gbs0554 [Streptococcus agalactiae NEM316]
emb|CAD46198.1| Unknown [Streptococcus agalactiae NEM316]
Length = 411
Score = 94.4 bits (233), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 106/402 (26%), Positives = 188/402 (46%), Gaps = 35/402 (8%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE--EEE 127
+ + GP + + + K L++Y K++ AL +L+K Y QE E
Sbjct: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGAL------ELLIKPYDTYQEFTGEG 116
Query: 128 KPLALAA---IKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRR 180
KP I +L G H GL + +P + N+ T +NL F K R
Sbjct: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K A G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A
Sbjct: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
Query: 241 KVNI----------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEF 290
+N +KL++ L +Q+ T + + ++R +L +Q ASL++ E
Sbjct: 236 TLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEV 294
Query: 291 EGFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGII 349
E F ++ ++VV+AG L I L++G +F KFY +L + Q+A +
Sbjct: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYIMQEALKRQST 354
Query: 350 WANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
+ N G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 FYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
>emb|CAA73372.1| femA [Staphylococcus hominis]
Length = 420
Score = 94.4 bits (233), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 90/388 (23%), Positives = 177/388 (45%), Gaps = 22/388 (5%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVMDYLDRDLVAFTMK 94
K+ + + +GI ++ +V + +L + P+ + Y RGPV+DY +++LV F
Sbjct: 33 KVAEKTETHLVGIKNKDNEVIAACMLTAV-PVMKIFKYFYSNRGPVIDYENKELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L+++ DP + + + +++ G G T
Sbjct: 92 ELSKYLKQQHCLYVRIDPYLPYQYRNHDGDITGNAGNDWFFDKMKQLGYQHEGFTTGFDP 151
Query: 155 SIQPRFQANIY----TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q RF + + T +++ +R K ++ GVK +++ EL F + T
Sbjct: 152 ILQIRFHSVLNLKDKTAKDVLNGMDSLRKRNTKKVQKNGVKVRFLTKEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQK 270
+ K S R ++++ + D+ + LA + + L++ + +N+D+ + +
Sbjct: 212 SETKEFSDREDSFYYNRFDHFKDRVLVPLAYIKFDEYLEELHAERQTLNKDLNKALKDIE 271
Query: 271 KRL--KKLEDQKASLERYITEFEGFTDQYPEEVVVAGI-LSISYG----NVMEMLY--AG 321
KR KK +++K +LE+ + E D+ + + G L IS G N E++Y G
Sbjct: 272 KRPDNKKAQNKKINLEQQLKANEQKIDEATQLQLEHGNELPISAGFFFINPFEVVYYAGG 331
Query: 322 MNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIE 376
++ ++ F Y + + A GI N G+ G D G+ KFK F +
Sbjct: 332 TSNKYRHFAGSYAVQWTMINYAIDHGIDRYNFYGISGHFTDDAEDAGVVKFKKGFNADVI 391
Query: 377 EFIGEFNLPVS-PLYHIANTMYKIRKQL 403
E++G+F P++ P+Y + T+ KI+K+L
Sbjct: 392 EYVGDFVKPINKPMYSLYTTLKKIKKRL 419
>ref|YP_001679516.1| methicillin resistance protein, putative [Heliobacterium
modesticaldum Ice1]
gb|ABZ83505.1| methicillin resistance protein, putative [Heliobacterium
modesticaldum Ice1]
Length = 356
Score = 93.6 bits (231), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 94/412 (22%), Positives = 171/412 (41%), Gaps = 86/412 (20%)
Query: 13 SEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPL-G 69
+E + F+ EH + VLQ +W +K++ WQ R+ + + +A++S+L + +P+ G
Sbjct: 10 DKERFNRFMAEHPKGHVLQSWEWGDVKSRTGWQPHRLMVEEAGTPLAAVSILKRRIPVVG 69
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
+ I Y PRGPV+D D ++ ++ + +KALF+K DP ++ + +
Sbjct: 70 KHIFYAPRGPVIDPARPDAADRLLEGIEALARREKALFLKIDPDVIDP-----APDWTEY 124
Query: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLE---MQFPKHTRRLIKDAK 186
L + + + E + +QPRF + ++L+ +F + TR I+ A+
Sbjct: 125 LCSRGFRRVDKG---------EGFEGVQPRFVFRLDISDDLDQIFARFHQKTRYNIRLAE 175
Query: 187 QRGVKTYR-VSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIP 245
++GV + EL F K++ T +R N +R+ AYF+ + +P
Sbjct: 176 KKGVVIDEDCGKEELPLFYKVLKETSERDNFLVRSYAYFEDMWDNL------------VP 223
Query: 246 QKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAG 305
+ K + RY E +AG
Sbjct: 224 AGM------------------------------AKLFIARYQGE------------AIAG 241
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD--- 362
L+ G +Y ++ + P YLL + A +G + GV G + +
Sbjct: 242 TLAFILGKKAWYIYGASSNRHRNVMPNYLLQWKMICWAKAEGCTLYDFRGVPGQVGEDHP 301
Query: 363 --GLTKFKANFAPTIEEFIGEFNLPVSP----LYHIANTMYK--IRKQLKNK 406
GL +FK F FIGE++ P L+++A MY+ +RK L +
Sbjct: 302 LYGLVRFKRGFNGDYVGFIGEYDRVYQPFFYHLWNVAEPMYQNLVRKALSRR 353
>ref|YP_141007.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme [Streptococcus thermophilus CNRZ1066]
gb|AAV62192.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme [Streptococcus thermophilus CNRZ1066]
Length = 411
Score = 93.2 bits (230), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 105/405 (25%), Positives = 181/405 (44%), Gaps = 29/405 (7%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLP 67
I +++EE ++ ++ + S +Q + AK+ K + + +KE Q+ +++ +
Sbjct: 4 IQVTKEEFNTHAQQVSERSFMQTEEMAKLLEKRGFSISYVA-WKEGNQIEVSAIVYSMPM 62
Query: 68 LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL--FIK-YDPAILLKQYALGQE 124
G + + GP+ + L F + LKDY K AL IK YD +
Sbjct: 63 TGGLRMEVNCGPIHSSVAH-LSDF-YQCLKDYAKANGALELVIKPYDTYQIFDSNGEPIS 120
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF----QANIYTQENLEMQFPKHTRR 180
E+K L I L + G + GL +P + + + +++L F K +
Sbjct: 121 SEQKQL----ISQLTDLGYSFDGLQTGYPGG-EPDWHYVKELSGIEEKDLIKSFSKKGKP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K AK G+K ++ + EL F +I S T R+ S ++ Y+Q +GD A +A
Sbjct: 176 LVKKAKTFGIKLKKLKRDELSIFKEITSATSDRREYSDKSLDYYQDFYDAFGDNADFMVA 235
Query: 241 KVNIPQKLD-------QYRQQLILINQDITRTQAHQKK--RLKKLEDQKASLERYITEFE 291
+N D + R +++ + D+ +KK +L++L Q + + E
Sbjct: 236 TLNFQDYFDHLESNQAKLRARIVKLQADLETNPTSEKKQNQLRELSSQFETFDVRKGEAT 295
Query: 292 GFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
F D+Y E++V+AG L + L++G +F KFY LL V A + GI +
Sbjct: 296 AFIDKYGQEDIVLAGSLFVYTPQEAVYLFSGSYPEFNKFYAPALLQEYVMTQAIKRGIGF 355
Query: 351 ANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPLYHIA 393
N G+ G D DG+ +FK NF I +G F PL + A
Sbjct: 356 YNFLGIMGIFDGSDGVLRFKQNFNGYIVRKMGTFRYYPQPLKYKA 400
>ref|YP_139117.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme, [Streptococcus thermophilus LMG 18311]
gb|AAV60302.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme, [Streptococcus thermophilus LMG 18311]
Length = 411
Score = 92.8 bits (229), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 105/405 (25%), Positives = 181/405 (44%), Gaps = 29/405 (7%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLP 67
I +++EE ++ ++ + S +Q + AK+ K + + +KE Q+ +++ +
Sbjct: 4 IQVTKEEFNTHAQQVSERSFMQTEEMAKLLEKRGFSISYVA-WKEGNQIEVSAIVYSMPM 62
Query: 68 LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL--FIK-YDPAILLKQYALGQE 124
G + + GP+ + L F + LKDY K AL IK YD +
Sbjct: 63 TGGLRMEVNCGPIHSSVAH-LSDF-YQCLKDYAKENGALELVIKPYDTYQIFDSNGEPIS 120
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF----QANIYTQENLEMQFPKHTRR 180
E+K L I L + G + GL +P + + + +++L F K +
Sbjct: 121 SEQKQL----ISQLTDLGYSFDGLQTGYPGG-EPDWHYVKELSGIEEKDLIKSFSKKGKP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K AK G+K ++ + EL F +I S T R+ S ++ Y+Q +GD A +A
Sbjct: 176 LVKKAKTFGIKLKKLKRDELSIFKEITSATSDRREYSDKSLDYYQDFYDAFGDNADFMVA 235
Query: 241 KVNIPQKLD-------QYRQQLILINQDITRTQAHQKK--RLKKLEDQKASLERYITEFE 291
+N D + R +++ + D+ +KK +L++L Q + + E
Sbjct: 236 TLNFQDYFDHLESNQAKLRARIVKLQADLETNPTSEKKQNQLRELSSQLETFDVRKGEAT 295
Query: 292 GFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
F D+Y E++V+AG L + L++G +F KFY LL V A + GI +
Sbjct: 296 AFIDKYGQEDIVLAGSLFVYTPQEAVYLFSGSYPEFNKFYAPALLQEYVMTQAIKRGIGF 355
Query: 351 ANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPLYHIA 393
N G+ G D DG+ +FK NF I +G F PL + A
Sbjct: 356 YNFLGIMGIFDGSDGVLRFKQNFNGYIVRKMGTFRYYPQPLKYKA 400
>ref|YP_820103.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus
thermophilus LMD-9]
gb|ABJ65907.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus
thermophilus LMD-9]
Length = 411
Score = 92.8 bits (229), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 105/405 (25%), Positives = 181/405 (44%), Gaps = 29/405 (7%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLP 67
I +++EE ++ ++ + S +Q + AK+ K + + +KE Q+ +++ +
Sbjct: 4 IQVTKEEFNTHAQQVSERSFMQTEEMAKLLEKRGFSISYVA-WKEGNQIEVSAIVYSMPM 62
Query: 68 LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKAL--FIK-YDPAILLKQYALGQE 124
G + + GP+ + L F + LKDY K AL IK YD +
Sbjct: 63 TGGLRMEVNCGPIHSSVAH-LSDF-YQCLKDYAKANGALELVIKPYDTYQIFDSNGEPIS 120
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF----QANIYTQENLEMQFPKHTRR 180
E+K L I L + G + GL +P + + + +++L F K +
Sbjct: 121 SEQKQL----ISQLTDLGYSFDGLQTGYPGG-EPDWHYVKELSGIEEKDLIKSFSKKGKP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+K AK G+K ++ + EL F +I S T R+ S ++ Y+Q +GD A +A
Sbjct: 176 LVKKAKTFGIKLKKLKRDELSIFKEITSATSDRREYSDKSLDYYQDFYDAFGDNADFMVA 235
Query: 241 KVNIPQKLD-------QYRQQLILINQDITRTQAHQKK--RLKKLEDQKASLERYITEFE 291
+N D + R +++ + D+ +KK +L++L Q + + E
Sbjct: 236 TLNFQDYFDHLESNQAKLRARIVKLQADLETNPKSEKKQNQLRELSSQFETFDVRKREAT 295
Query: 292 GFTDQYP-EEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
F D+Y E++V+AG L + L++G +F KFY LL V A + GI +
Sbjct: 296 AFIDKYGQEDIVLAGSLFVYTPQEAVYLFSGSYPEFNKFYAPALLQEYVMTQAIKRGIGF 355
Query: 351 ANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPLYHIA 393
N G+ G D DG+ +FK NF I +G F PL + A
Sbjct: 356 YNFLGIMGIFDGSDGVLRFKQNFNGYIVRKMGTFRYYPQPLKYKA 400
>gb|AAD45259.1|AF145333_1 methicillin resistance protein FemA [Staphylococcus cohnii subsp.
urealyticus]
Length = 419
Score = 91.7 bits (226), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 94/420 (22%), Positives = 187/420 (44%), Gaps = 32/420 (7%)
Query: 12 ISEEEHDSFVKE--HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++ +E +FV + + + G+ KI + +G+ E +V + LL + P+
Sbjct: 6 LTAKEFGAFVDHMPNSHFTQMVGNYELKIAEGTETHLVGVKNNENEVIAACLLTAV-PVM 64
Query: 70 R--SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEE 127
+ Y RGPV+D+ +++LV + L Y K AL+++ DP + + + E
Sbjct: 65 KIFKYFYTNRGPVIDFENKELVHYFFNELTKYVKKHNALYLRVDPYLAYQYRNHDGDVLE 124
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIK 183
+++ G G IQ RF + + T +++ +R K
Sbjct: 125 NAGHDWIFDKMKQLGYKHQGFLTGFDPIIQIRFHSVLDLKDKTAKDVLNDMDSLRKRNTK 184
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
++ GVK + + EL F + T + K+ R ++++ + Y ++ + LA ++
Sbjct: 185 KVQKNGVKVRFLGEDELPIFRSFMEDTSESKDFDDREDSFYYNRLKYYKNRVLVPLAYMD 244
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQKKRL--KKLEDQKASLERY-------ITEFEGFT 294
+D+ + + ++++DI + KR KK ++K +LE+ I E +
Sbjct: 245 FEAYIDELKSEREVLSKDINKALKDIAKRPENKKAYNKKENLEKQLIANQQKIDEAKSLQ 304
Query: 295 DQYPEEVVVAGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWAN 352
+Q+ E+ ++ I N E++Y G +++F+ F Y + + A + I N
Sbjct: 305 EQHGNELPISAAFFIV--NPYEVVYYAGGTSNEFRHFAGSYAIQWKMINYAIDNNIDRYN 362
Query: 353 MGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQLKNK 406
G+ G D G+ KFK F + E++G+F P++ P+Y I Y + K LK+K
Sbjct: 363 FYGISGDFSEEAEDAGVVKFKKGFNADVVEYVGDFIKPINKPMYKI----YTMVKGLKDK 418
>ref|YP_001694094.1| MurN [Streptococcus pneumoniae Hungary19A-6]
gb|AAK07416.1| MurN [Streptococcus pneumoniae]
gb|AAY56881.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
gb|ACA36790.1| MurN [Streptococcus pneumoniae Hungary19A-6]
Length = 410
Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 95/364 (26%), Positives = 168/364 (46%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + E P+ + I+ L + G + GLTM +P +
Sbjct: 100 --ELLVKPYETYQTFDSEGNPIDAEKKSIIQGLTDLGYQFDGLTMGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T++NL F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKNLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKL-----DQYRQQLIL--INQDITRTQAHQKK--R 272
Y++ ++G++A +A +N + + +Q + + IL + D+++ +KK +
Sbjct: 217 EYYEHFYDSFGEQAEFLIASLNFSEYMSKLQGEQSKLEEILDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>ref|YP_253447.1| factor essential for methicillin resistance A(FemA) protein
[Staphylococcus haemolyticus JCSC1435]
dbj|BAE04841.1| factor essential for methicillin resistance A(FemA) protein
[Staphylococcus haemolyticus JCSC1435]
Length = 420
Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 90/388 (23%), Positives = 174/388 (44%), Gaps = 22/388 (5%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVMDYLDRDLVAFTMK 94
K+ N+ + +GI ++ +V + +L +P+ + Y RGPV+DY +R+LV F
Sbjct: 33 KVANKTETHLVGIKNKDNEVIAACMLT-AVPVMKFFKYFYSNRGPVIDYDNRELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K L+++ DP + + E ++ G G T
Sbjct: 92 ELTKYLKQHNCLYVRVDPYLPYQYLNHDGEITGNAGNDWFFDKMKHLGFKHEGFTKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
Q R+ + + T +++ +R K ++ GVK +S+ EL F + T
Sbjct: 152 IKQIRYHSVLDLKNKTSKDILNGMDSLRKRNTKKVQKNGVKVKFLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQK 270
+ K R+++++ + D+ + LA + + +++ + + +N+D+ + +
Sbjct: 212 TETKEFQDRDDSFYYNRYRHFKDRVLVPLAYIKFDEYIEELQNERETLNKDVNKALKDIE 271
Query: 271 KRL--KKLEDQKASLERYITEFEGFTDQYPEEVVVAGI-LSISYG----NVMEMLY--AG 321
KR KK ++K +LE+ + + D+ + G L IS G N E++Y G
Sbjct: 272 KRPDNKKAFNKKENLEKQLDANQQKLDEAKKLQAEHGNELPISAGFFFINPFEVVYYAGG 331
Query: 322 MNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANFAPTIE 376
++ ++ F Y + + A GI N G+ G+ D G+ KFK F +
Sbjct: 332 TSNKYRHFAGSYAIQWTMINYAIDHGIDRYNFYGISGNFSEDAEDVGVIKFKKGFNADVI 391
Query: 377 EFIGEFNLPVS-PLYHIANTMYKIRKQL 403
E++G+F P++ PLY + T+ KI+K+
Sbjct: 392 EYVGDFVKPINKPLYSVYKTLKKIKKRF 419
>ref|ZP_00121081.2| COG2348: Uncharacterized protein involved in methicillin resistance
[Bifidobacterium longum DJO10A]
Length = 391
Score = 90.5 bits (223), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 86/364 (23%), Positives = 161/364 (44%), Gaps = 29/364 (7%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
KE +++ + +L + I GP+ DY D + + F M LK + K K A ++
Sbjct: 18 KEGEKIVAAALFETHRSRFSTFAVIHDGPMCDYHDTEALTFFMDALKRHAKAKGASQLEI 77
Query: 111 DPAILLK-----QYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ---- 161
P + +L ++ P I+ L+ G G T + + PR++
Sbjct: 78 TPESPYRLRDTNGASLPDDQNGAP-DNKLIEQLEAIGFTHGGFT--VGYTAVPRWRYLKD 134
Query: 162 -ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRN 220
I +++L + K T+ +K A+ GV +S EL F++I T +R++ R
Sbjct: 135 LTGITDEKSLLKSYDKRTQWSVKRAQSMGVHVRELSDDELGVFARIEQQTAERRSFEYRG 194
Query: 221 EAYFQKLMTTYGDKAYLHLAKVNIPQ---KLDQYRQQL-----ILINQDITRTQAHQKKR 272
EAYF + +G KA+ +A+++I + + R+ L L ++ +++
Sbjct: 195 EAYFHRFKEAFGSKAHFMVAEIHIDEYVADMTSKREALSAKVAALTAKNAEHPTTKTERQ 254
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQ 332
L + A++E+ + E F + + A L + + + L++G + +K FY
Sbjct: 255 LGEETRNLAAVEKRLNEAAEFAKD-GDVLPAAASLFVEHPREVIYLFSGSVEQYKPFYAS 313
Query: 333 YLL-YPNVFQDAYQDGIIWANMGGVEGSLDD------GLTKFKANFAPTIEEFIGEFNLP 385
L+ + + + G+ N G++G DD G+ +FK F +EE GEF LP
Sbjct: 314 ALIQHDAMLHFCVEHGLSRYNFYGIDGVFDDPDDEGRGVLEFKQGFNGYVEELPGEFVLP 373
Query: 386 VSPL 389
V P+
Sbjct: 374 VKPV 377
>gb|AAC69636.1| factor essential for methicillin resistance FEMA [Staphylococcus
schleiferi]
Length = 421
Score = 90.1 bits (222), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 97/406 (23%), Positives = 178/406 (43%), Gaps = 30/406 (7%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVM 81
+ + + G+ K+ + +GI V + LL + P+ + Y RGPVM
Sbjct: 20 YSHFTQMVGNYELKVAEGVETHLVGIKDNNNNVLAACLLTAV-PVMKFFKYFYSNRGPVM 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEA 141
DY +++LV F L Y K AL+++ DP + + + E E+ + + E
Sbjct: 79 DYENKELVHFFFNELSKYVKKYHALYLRVDPYLPMLKRNHDGEVIERYGSDWFFDKMAEL 138
Query: 142 GVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQ 197
G T Q RF + + T +++ Q +R K ++ GVK +++
Sbjct: 139 NFEHEGFTTGFDTIRQIRFHSVLDVENKTSKDILNQMDNLRKRNTKKVQKNGVKVRYLNE 198
Query: 198 SELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQ------- 250
ELH F + T + K+ R++ ++ M Y D+ + LA ++ L +
Sbjct: 199 DELHIFRSFMEDTSETKDFVDRDDDFYYHRMKYYKDRVRVPLAYIDFNAYLAELNTEAQD 258
Query: 251 YRQQLILINQDITRTQAHQK--KRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGIL 307
+++++ ++DI + +QK + K LE Q + + I E E ++ + + + AG
Sbjct: 259 FKKEIAKADKDIDKRPENQKAINKKKNLEQQLEANQAKIKEAETLQLKHGDTLPISAGFF 318
Query: 308 SISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL----- 360
I N E++Y G ++F+ F Y + + A I N G+ G
Sbjct: 319 II---NPFEVVYYAGGTANEFRHFAGSYAVQWEMINYAIDYQIPRYNFYGISGDFSEDAE 375
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRKQLKNK 406
D G+ KFK + + E++G+F + P+ A T+Y KQLK+K
Sbjct: 376 DAGVIKFKKGYNAEVIEYVGDF---IKPINKPAYTVYLKLKQLKDK 418
>gb|AAC69631.1| factor essential for methicillin resistance FEMA [Staphylococcus
haemolyticus]
Length = 420
Score = 90.1 bits (222), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 90/388 (23%), Positives = 173/388 (44%), Gaps = 22/388 (5%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVMDYLDRDLVAFTMK 94
K+ N+ + +GI ++ +V + +L +P+ + Y RGPV+DY +R+LV F
Sbjct: 33 KVANKTETHLVGIKNKDNEVIAACMLT-AVPVMKFFKYFYSNRGPVIDYDNRELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K L+++ DP + + E ++ G G T
Sbjct: 92 ELTKYLKQHNCLYVRVDPYLPYQYLNHDGEITGNAGNDWFFDKMKHLGFEHEGFTKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
Q R+ + + T +++ +R K ++ GVK +S+ EL F + T
Sbjct: 152 IKQIRYHSVLDLKNKTSKDILNGMDSLRKRNTKKVQKNGVKVKFLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQK 270
+ K R+++++ + D + LA + + +++ + + +N+D+ + +
Sbjct: 212 TETKEFQDRDDSFYYNRYRHFKDHVLVPLAYIKFDEYIEELQNERETLNKDVNKALKDIE 271
Query: 271 KRL--KKLEDQKASLERYITEFEGFTDQYPEEVVVAGI-LSISYG----NVMEMLY--AG 321
KR KK ++K +LE+ + + D+ + G L IS G N E++Y G
Sbjct: 272 KRPDNKKAFNKKENLEKQLDANQQKLDEAKKLQAEHGNELPISAGFFFINPFEVVYYAGG 331
Query: 322 MNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANFAPTIE 376
++ ++ F Y + + A GI N G+ G+ D G+ KFK F +
Sbjct: 332 TSNKYRHFAGSYAIQWTMINYAIDHGIDRYNFYGISGNFSEDAEDVGVIKFKKGFNADVI 391
Query: 377 EFIGEFNLPVS-PLYHIANTMYKIRKQL 403
E++G+F P++ PLY + T+ KI+K+
Sbjct: 392 EYVGDFVKPINKPLYSVYKTLKKIKKRF 419
>ref|YP_001623976.1| methicillin resistance protein [Renibacterium salmoninarum ATCC
33209]
gb|ABY22562.1| methicillin resistance protein [Renibacterium salmoninarum ATCC
33209]
Length = 428
Score = 89.7 bits (221), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 91/405 (22%), Positives = 169/405 (41%), Gaps = 29/405 (7%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLI-KLL 66
+ ++E E ++F H+Q + LQ K + WQ +G+ ++ V + +LL + +
Sbjct: 4 VQLTEHEFEAFEANHRQGNFLQSVVMGKRRQSTGWQMHLVGLKNDDGAVVAAALLSSRKV 63
Query: 67 PLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEE 126
LG S +GPV+DY D +++A + LK Y +AL +P +LL L E
Sbjct: 64 FLGYSDFDCAQGPVLDYDDAEVLAAFLTGLKGYLHEHRALRTTLNPTVLLTHRDLDAELI 123
Query: 127 EKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF--------QANIYTQENLEMQFPKHT 178
+ + K +++ +W P + I + L F
Sbjct: 124 DD--GYSGWKYVEQFEANWFSHQDNAEVDRDPHLFRWFFSKDLSGITNADELTASFDSRA 181
Query: 179 RRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYG-DKAYL 237
+R ++ + + GV+ + + +L +F ++ T +R+ R+++Y L D+
Sbjct: 182 QRSLQTSIKSGVEVSVLGREQLDEFHDVLKHTAERRGFEYRDKSYHHSLAEFLSPDELKF 241
Query: 238 HLAKVN-------IPQKLDQYRQQLILINQDITRTQAHQK--KRLKKLEDQKASLERYIT 288
A++N + Q LD+ + ++ + + + K RL+ ++ AS + +
Sbjct: 242 CAARLNTQVYGEFLQQSLDKQQTEVRKAEDALAKNPENVKAQNRLRAAQEAVASGDVKLK 301
Query: 289 EFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGI 348
+ + ++ G+ IS+ N M L G DD+ F + L+ Q A Q GI
Sbjct: 302 QLDELKANGANPILAVGLF-ISHANEMVFLAGGSYDDYASFRAPFSLHWFAMQQAMQAGI 360
Query: 349 IWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSP 388
N G G G+ FK F EE IG F+L +P
Sbjct: 361 TRYNFYGTNGEFSGNPEQHGVYLFKRGFGGVSEERIGYFSLVSTP 405
>gb|AAB52984.1| FemA
Length = 418
Score = 89.4 bits (220), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 88/403 (21%), Positives = 177/403 (43%), Gaps = 28/403 (6%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + + G+ K+ + +G+ ++ V + LL +P+ + Y RGPV+
Sbjct: 20 YSHFTQMVGNYELKVAEGTETHLVGVKDKDDNVIAACLLT-AVPVMKFFKYFYSNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEA 141
DY +++LV + + LK Y K AL+++ DP + + E +++
Sbjct: 79 DYDNKELVHYFFRELKAYVKQYNALYLRVDPYLPYQYRNHDGEITGNAGHDWIFDKMEQL 138
Query: 142 GVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQ 197
G G T IQ RF + + T +++ +R K K+ GVK + +
Sbjct: 139 GYIHQGFTTGFDPIIQIRFHSVLDLKDKTPQDVLKGMDSLRKRNTKKVKRNGVKVRFLGE 198
Query: 198 SELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR----- 252
E+H F K + T + K+ R + ++ + Y ++ + +A ++ +++
Sbjct: 199 DEMHIFRKFMEDTAEAKDFDDREDDFYYHRLKHYKNRVLVPMAYIDFEDYINELNAEQKN 258
Query: 253 --QQLILINQDITRTQAHQKKRLKK--LEDQKASLERYITEFEGFTDQYPEEV-VVAGIL 307
+++ +D+ + +QK KK LE Q + + + E ++ E+ + AG
Sbjct: 259 LEKEINKAEKDLNKNPENQKAARKKENLEQQLEAHHQKVAEARDLQQKHGNELPISAGFF 318
Query: 308 SISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL----- 360
I N E++Y G ++++ F Y + + A GI N G+ G
Sbjct: 319 II---NPFEVVYYAGGTANEYRHFAGSYAVQWEMINYAINHGIDRYNFYGISGHFTEDAE 375
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQ 402
D G+ KFK F + E++G+F P++ P+Y + T+ KI+ +
Sbjct: 376 DAGVVKFKKGFNADVIEYVGDFIAPINKPMYKLYTTLKKIKDR 418
>gb|AAC69633.1| factor essential for methicillin resistance FEMA [Staphylococcus
capitis]
Length = 417
Score = 89.0 bits (219), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 87/402 (21%), Positives = 178/402 (44%), Gaps = 28/402 (6%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + ++G+ K+ + +GI + QV + LL + P+ + Y RGPV+
Sbjct: 20 YSHFTQMEGNYELKVAEGTDSHLVGIKNNDNQVIAACLLTAV-PVMKIFKYFYSNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEA 141
DY +++LV F L Y K L+++ DP + + E ++E
Sbjct: 79 DYDNKELVHFFFNELSKYVKKHNCLYLRVDPYLPYQYLNHDGEIIGNAGHDWFFNKMEEL 138
Query: 142 GVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQ 197
G G +Q R+ + + T +++ +R K ++ GVK +S+
Sbjct: 139 GFEHEGFHKGFHPILQVRYHSVLDLKDKTAKDVLKGMDSLRKRNTKKVQKNGVKVRFLSE 198
Query: 198 SELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLIL 257
EL F + T + K + R+++++ + + D+ + LA V+ + +++ + +
Sbjct: 199 DELPIFRSFMEDTTETKEFADRDDSFYYNRLKYFKDRVLVPLAYVDFDEYIEELNNERDV 258
Query: 258 INQDITRTQAHQKKR---------LKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGIL 307
+N+D+ + +KR L+ Q + ++ I E + ++ E+ + AG
Sbjct: 259 LNKDLNKALKDIEKRPDNKKAYNKRDNLQQQLDANQQKIDEAKNLQQEHGNELPISAGYF 318
Query: 308 SISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL----- 360
I N E++Y G ++ ++ + Y + + A + GI N GV G
Sbjct: 319 FI---NPFEVVYYAGGTSNRYRHYAGSYAIQWKMINYALEHGINRYNFYGVSGDFSEDAE 375
Query: 361 DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRK 401
D G+ KFK + + E++G+F P++ P+Y I N + K++K
Sbjct: 376 DVGVIKFKKGYNADVIEYVGDFIKPINKPMYAIYNALKKLKK 417
>gb|AAD22132.1|U23711_1 FEMA [Staphylococcus haemolyticus]
Length = 420
Score = 89.0 bits (219), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 89/385 (23%), Positives = 172/385 (44%), Gaps = 22/385 (5%)
Query: 40 NQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVMDYLDRDLVAFTMKTLK 97
N+ + +GI ++ +V + +L +P+ + Y RGPV+DY +R+LV F L
Sbjct: 36 NKTETHLVGIKNKDNEVIAACMLT-AVPVMKFFKYFYSNRGPVIDYDNRELVHFFFNELT 94
Query: 98 DYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQ 157
Y K L+++ DP + + E ++ G G T Q
Sbjct: 95 KYLKQHNCLYVRVDPYLPYQYLNHDGEITGNAGNDWFFDKMKHLGFEHEGFTKGFDPIKQ 154
Query: 158 PRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKR 213
R+ + + T +++ +R K ++ GVK +S+ EL F + T +
Sbjct: 155 IRYHSVLDLKNKTSKDILNGMDSLRKRNTKKVQKNGVKVKFLSEEELPIFRSFMEDTTET 214
Query: 214 KNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRL 273
K R+++++ + D+ + LA + + +++ + + +N+D+ + +KR
Sbjct: 215 KEFQDRDDSFYYNRYRHFKDRVLVPLAYIKFDEYIEELQNERETLNKDVNKALKDIEKRP 274
Query: 274 --KKLEDQKASLERYITEFEGFTDQYPEEVVVAGI-LSISYG----NVMEMLY--AGMND 324
KK ++K +LE+ + + D+ + G L IS G N E++Y G ++
Sbjct: 275 DNKKAFNKKENLEKQLDANQQKLDEAKKLQAEHGNELPISAGFFFINPFEVVYYAGGTSN 334
Query: 325 DFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANFAPTIEEFI 379
++ F Y + + A GI N G+ G+ D G+ KFK F + E++
Sbjct: 335 KYRHFAGSYAIQWTMINYAIDHGIDRYNFYGISGNFSEDAEDVGVIKFKKGFNADVIEYV 394
Query: 380 GEFNLPVS-PLYHIANTMYKIRKQL 403
G+F P++ PLY + T+ KI+K+
Sbjct: 395 GDFVKPINKPLYSVYKTLKKIKKRF 419
>gb|AAD33941.1|AF144662_1 factor essential for methicillin resistance [Staphylococcus
intermedius]
Length = 421
Score = 88.6 bits (218), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 93/409 (22%), Positives = 175/409 (42%), Gaps = 36/409 (8%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVM 81
+ + + G+ K+ + +GI + QV + LL + P+ + Y RGPVM
Sbjct: 20 YSHFTQMVGNYELKVAEGVETHLVGIKDNQNQVLAACLLTAV-PVMKVFKYFYTNRGPVM 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEA 141
DY +++LV F L Y K AL+++ DP + + + E E+ + +
Sbjct: 79 DYENQELVHFFFNELTKYVKKYNALYVRVDPYLPMLKRNHDGEVIERFQNDWFFDKMAQL 138
Query: 142 GVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQ 197
G G T Q RF + + T +++ +R K ++ GVK + +
Sbjct: 139 GFEHEGFTTGFDTVRQIRFHSVLDVEGKTAKDILNNMDSLRKRNTKKVQKNGVKVRFLDE 198
Query: 198 SELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLIL 257
+ELH + T + K+ R + ++ + Y D+ + LA ++ + + +
Sbjct: 199 NELHILRSFMEDTSETKDFVDREDDFYYHRLKHYKDRVLVPLAYIDFTTYIPGLKSE--- 255
Query: 258 INQDITRTQAHQKKRLKKLEDQKASLER-------------YITEFEGFTDQYPEEV-VV 303
QD + A +K L+K D + +L + I E E ++ + + +
Sbjct: 256 -EQDFHKQIAKTEKELEKRPDNQKALNKKKNLMQQLEANQAKIQEAEQLQAKHGDTLPIS 314
Query: 304 AGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL- 360
AG I N E++Y G ++F+ F Y + + A + I N G+ G
Sbjct: 315 AGFFII---NPFEVVYYAGGTANEFRHFAGSYAVQWEMINYAIEHDIPRYNFYGISGHFT 371
Query: 361 ----DDGLTKFKANFAPTIEEFIGEFNLPV-SPLYHIANTMYKIRKQLK 404
D G+ KFK + + E++G+F PV P+Y I T+ +++K++K
Sbjct: 372 EDAEDAGVVKFKKGYNADVIEYVGDFIKPVQKPVYKIYTTLKQLKKKIK 420
>emb|CAJ88363.1| conserved hypothetical protein [Streptomyces ambofaciens ATCC
23877]
Length = 373
Score = 88.2 bits (217), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 96/427 (22%), Positives = 169/427 (39%), Gaps = 83/427 (19%)
Query: 4 LTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV--ASLSL 61
+T + K+ I+ EEH FV +S LQ W +K W+ E +G + E + A L L
Sbjct: 1 MTCHLKV-ITREEHLRFVAARPSVSHLQIPAWGDVKPDWRAESLGWFDEGGDLVGAGLVL 59
Query: 62 LIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA- 120
L L + R + Y+P GPV+D+ DL + ++ + Y K + A ++ P ++ ++++
Sbjct: 60 LRPLPGVRRYLAYLPEGPVVDWAATDLERW-LEPMLAYLKGRGAFSVRMGPPVVARRWSA 118
Query: 121 --------------LGQEEE--EKPLALAAIKNLQEAGVHWTGLTMEIA-DSIQPRFQAN 163
LG E +P A + L G T E + QPR+
Sbjct: 119 EAVKAAIADRAGRRLGDVEATVREPGADGVAQQLLRMGWRRTEPGGEDGFAAGQPRYVCQ 178
Query: 164 I----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLR 219
+ + + ++ F + RR IK A + GVK R Q +L F ++ + T +R + R
Sbjct: 179 VPLTGRSLDQIQNGFNQQWRRNIKKADKAGVKVVRGDQEDLPAFYELYAETAERDRFAPR 238
Query: 220 NEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQ 279
YFQ++ T L +D R
Sbjct: 239 PLTYFQRMWTA--------------------------LTAEDPDR--------------- 257
Query: 280 KASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ Y+ +G V+A ++ G + Y ++ P L +
Sbjct: 258 ---MRLYLAHHDG--------DVLAAATMLTVGEHVWYSYGASTARRREVQPNNALQWRM 306
Query: 340 FQDAYQDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIAN 394
DA++ G + G+ +LD+ GL +FK E++GE+ P++ + H A
Sbjct: 307 MCDAHELGAAVYDFRGITDTLDEDNHLLGLLRFKTGAGGEAVEYLGEWEYPLNRVLHRAL 366
Query: 395 TMYKIRK 401
+Y R+
Sbjct: 367 GLYMARR 373
>ref|NP_688347.1| beta-lactam resistance factor [Streptococcus agalactiae 2603V/R]
gb|AAN00220.1|AE014253_18 beta-lactam resistance factor [Streptococcus agalactiae 2603V/R]
Length = 411
Score = 87.8 bits (216), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 98/382 (25%), Positives = 166/382 (43%), Gaps = 27/382 (7%)
Query: 28 SVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLD 85
S LQ + AK+ K + +G Y+ E ++ +SL + G + I GPV + +
Sbjct: 22 SFLQTPEMAKLLEKRGYDVRYLG-YQVENKLEIISLSYIMPVTGGFQMKIDSGPV--HSN 78
Query: 86 RDLVAFTMKTLKDYGKTKKALFI---KYDPAILLKQYALGQEEEEKPLALAAIKNLQEAG 142
+ K L+ Y K+ L + YD L + + L I++ +G
Sbjct: 79 SKYLKQFYKALQGYAKSNGVLELIVEPYDDYQLFTSSGVPSNQGNDNL----IEDFTSSG 134
Query: 143 VHWTGLTMEIADS-IQPRFQANI--YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSE 199
H GLT + + N+ T E L F K R L+K A G+K + + E
Sbjct: 135 YHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKAMSFGIKVRVLKRDE 194
Query: 200 LHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ-------KLDQYR 252
LH F +I + T R++ ++ Y+Q ++ KA +A +N + K +
Sbjct: 195 LHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFREYDHNLQIKAEALE 254
Query: 253 QQLILINQDITRTQAHQKKRLKKLE--DQKASLERYITEFEGFTDQYP-EEVVVAGILSI 309
+L L+++ K ++ E +Q AS E E + F +Y ++VV+AG L +
Sbjct: 255 NKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQKYDNQDVVLAGSLFV 314
Query: 310 SYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKF 367
++G +F KFY +L V Q+A + G + N+ G++G+ D D + +F
Sbjct: 315 YSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLGIQGTFDGSDSILRF 374
Query: 368 KANFAPTIEEFIGEFNLPVSPL 389
K NF I +G FN SP
Sbjct: 375 KQNFNGCIIRKMGTFNYYPSPF 396
>gb|AAC69634.1| factor essential for methicillin resistance FEMA [Staphylococcus
xylosus]
Length = 420
Score = 87.8 bits (216), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 87/396 (21%), Positives = 176/396 (44%), Gaps = 26/396 (6%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + + G+ KI + +GI + +V + LL + P+ + Y RGPV+
Sbjct: 20 NSHFTQMVGNYELKIAESTETHLVGIKNNDNEVIAACLLTAV-PVMKFFKYFYTNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEA 141
D+ +++LV + L Y K AL+++ DP + + E E +++
Sbjct: 79 DFENKELVHYFFNELSKYVKKHNALYLRVDPYLAYQYRNHDGEVLENAGHDWIFDKMKQL 138
Query: 142 GVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQ 197
G G IQ RF + + T +++ +R K ++ GVK + +
Sbjct: 139 GYKHQGFLTGFDSIIQIRFHSVLDLVGKTAKDVLNGMDSLRKRNTKKVQKNGVKVRFLRE 198
Query: 198 SELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLIL 257
EL F + T + K+ R++ ++ + Y D+ + LA ++ + +++ + + +
Sbjct: 199 DELPIFRSFMEDTSETKDFDDRDDGFYYNRLRYYKDRVLVPLAYMDFNEYIEELQAEREV 258
Query: 258 INQDITRTQAHQKKRL--KKLEDQKASLERY-------ITEFEGFTDQYPEEVVVAGILS 308
+++DI + +KR KK ++K +LE+ I E + +++ E+ ++
Sbjct: 259 LSKDINKAVKDIEKRPENKKAYNKKDNLEKQLIANQQKIDEAKTLQEKHGNELPISAAYF 318
Query: 309 ISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----D 361
I N E++Y G +++F+ F Y + + A I N G+ G D
Sbjct: 319 II--NPYEVVYYAGGTSNEFRHFAGSYAIQWKMINYAIDHNIDRYNFYGISGHFTEDAED 376
Query: 362 DGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTM 396
G+ KFK F + E++G+F P++ P+Y I T+
Sbjct: 377 AGVVKFKKGFNADVVEYVGDFIKPINKPMYKIYTTL 412
>emb|CAB89540.1| MurN protein [Streptococcus pneumoniae]
Length = 410
Score = 87.4 bits (215), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 94/369 (25%), Positives = 169/369 (45%), Gaps = 30/369 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + I GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMEINSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T++NL F K + L+K ++ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKNLLKSFSKKGKPLVKKSETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKL-----DQYRQQLIL--INQDITRTQAHQKK--R 272
Y++ ++G++A +A +N + + +Q + + IL + D+++ +KK +
Sbjct: 217 EYYEHFYDSFGEQAEFLIASLNFSEYMSKLQGEQSKLEEILDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMSQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIANTMYK 398
+ A + K
Sbjct: 397 KYKAIQLLK 405
>ref|ZP_02921095.1| hypothetical protein STRINF_01979 [Streptococcus infantarius subsp.
infantarius ATCC BAA-102]
gb|EDT46974.1| hypothetical protein STRINF_01979 [Streptococcus infantarius subsp.
infantarius ATCC BAA-102]
Length = 410
Score = 87.4 bits (215), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 76/283 (26%), Positives = 124/283 (43%), Gaps = 20/283 (7%)
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ----ANIYTQENLEMQFPKHTRR 180
++E+P I L E G H+ GL +P + E L+ F K R
Sbjct: 120 DDERP---GLITCLTELGYHFDGLQTGYPGG-EPDWHYVKDLTGLVPETLKKSFSKKGRP 175
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
L+ G+K R+ + ELH F I + T R+ + Y++ ++G+ +A
Sbjct: 176 LVNKTNSFGIKVRRLKRDELHIFKAITASTSARREYMDKPLDYYEAFYDSFGENCEFMIA 235
Query: 241 KVNIPQKL-------DQYRQQLILINQDITR--TQAHQKKRLKKLEDQKASLERYITEFE 291
+N L D+ +L ++NQ I A K+ +L+ Q A+ + + E +
Sbjct: 236 TLNFQDYLKNLQDSYDKIAAELAVLNQKIADGVNSAKVHKQKAQLDKQIATFDVRLKEAK 295
Query: 292 GFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW 350
+Y E+VV+AG L + L++G +F KFY L +V +A + GI +
Sbjct: 296 ELIQKYGSEDVVLAGSLFVYTPQEAVYLFSGSYTEFNKFYAPVALQEHVMTEALKRGINF 355
Query: 351 ANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPLYH 391
N G++G D DG+ +FK NF I +G F PL H
Sbjct: 356 YNFLGIQGIFDGSDGVLRFKQNFNGYIVRKMGTFRYYPRPLLH 398
>ref|ZP_00790772.1| beta-lactam resistance factor [Streptococcus agalactiae 515]
gb|EAO70492.1| beta-lactam resistance factor [Streptococcus agalactiae 515]
Length = 411
Score = 87.4 bits (215), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 98/382 (25%), Positives = 166/382 (43%), Gaps = 27/382 (7%)
Query: 28 SVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLD 85
S LQ + AK+ K + +G Y+ E ++ +SL + G + I GPV + +
Sbjct: 22 SFLQTPEMAKLLEKRGYDVRYLG-YRVENKLEIISLSYIMPVTGGFQMKIDSGPV--HSN 78
Query: 86 RDLVAFTMKTLKDYGKTKKALFI---KYDPAILLKQYALGQEEEEKPLALAAIKNLQEAG 142
+ K L+ Y K+ L + YD L + + L I++ +G
Sbjct: 79 SKYLKQFYKALQGYAKSNGVLELIVEPYDDYQLFTSSGVPSNQGNDNL----IEDFTSSG 134
Query: 143 VHWTGLTMEIADS-IQPRFQANI--YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSE 199
H GLT + + N+ T E L F K R L+K A G+K + + E
Sbjct: 135 YHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKAMSFGIKVRVLKRDE 194
Query: 200 LHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ-------KLDQYR 252
LH F +I + T R++ ++ Y+Q ++ KA +A +N + K +
Sbjct: 195 LHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFREYDHNLQIKAEALE 254
Query: 253 QQLILINQDITRTQAHQKKRLKKLE--DQKASLERYITEFEGFTDQYP-EEVVVAGILSI 309
+L L+++ K ++ E +Q AS E E + F +Y ++VV+AG L +
Sbjct: 255 NKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQKYDNQDVVLAGSLFV 314
Query: 310 SYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKF 367
++G +F KFY +L V Q+A + G + N+ G++G+ D D + +F
Sbjct: 315 YSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLGIQGTFDGSDSILRF 374
Query: 368 KANFAPTIEEFIGEFNLPVSPL 389
K NF I +G FN SP
Sbjct: 375 KQNFNGYIIRKMGTFNYYPSPF 396
>ref|ZP_02712499.1| alanine-adding enzyme MurN [Streptococcus pneumoniae SP195]
gb|EDT93445.1| alanine-adding enzyme MurN [Streptococcus pneumoniae SP195]
Length = 410
Score = 87.0 bits (214), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 92/369 (24%), Positives = 169/369 (45%), Gaps = 30/369 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT+ +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTIGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + ++L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIANTMYK 398
+ A + K
Sbjct: 397 KYKAIQLLK 405
>ref|NP_735856.1| hypothetical protein gbs1419 [Streptococcus agalactiae NEM316]
ref|ZP_00783864.1| beta-lactam resistance factor [Streptococcus agalactiae H36B]
ref|ZP_00787501.1| beta-lactam resistance factor [Streptococcus agalactiae CJB111]
emb|CAC83745.1| Fem-homologue [Streptococcus agalactiae]
emb|CAD47078.1| unknown [Streptococcus agalactiae NEM316]
gb|EAO73726.1| beta-lactam resistance factor [Streptococcus agalactiae CJB111]
gb|EAO77402.1| beta-lactam resistance factor [Streptococcus agalactiae H36B]
Length = 411
Score = 86.7 bits (213), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 98/382 (25%), Positives = 166/382 (43%), Gaps = 27/382 (7%)
Query: 28 SVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLD 85
S LQ + AK+ K + +G Y+ E ++ +SL + G + I GPV + +
Sbjct: 22 SFLQTPEMAKLLEKRGYDVRYLG-YQVENKLEIISLSYIMPVTGGFQMKIDSGPV--HSN 78
Query: 86 RDLVAFTMKTLKDYGKTKKALFI---KYDPAILLKQYALGQEEEEKPLALAAIKNLQEAG 142
+ K L+ Y K+ L + YD L + + L I++ +G
Sbjct: 79 SKYLKQFYKALQGYAKSNGVLELIVEPYDDYQLFTSSGVPSNQGNDNL----IEDFTSSG 134
Query: 143 VHWTGLTMEIADS-IQPRFQANI--YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSE 199
H GLT + + N+ T E L F K R L+K A G+K + + E
Sbjct: 135 YHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKAMSFGIKVRVLKRDE 194
Query: 200 LHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ-------KLDQYR 252
LH F +I + T R++ ++ Y+Q ++ KA +A +N + K +
Sbjct: 195 LHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFREYDHNLQIKAEALE 254
Query: 253 QQLILINQDITRTQAHQKKRLKKLE--DQKASLERYITEFEGFTDQYP-EEVVVAGILSI 309
+L L+++ K ++ E +Q AS E E + F +Y ++VV+AG L +
Sbjct: 255 NKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQKYDNQDVVLAGSLFV 314
Query: 310 SYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKF 367
++G +F KFY +L V Q+A + G + N+ G++G+ D D + +F
Sbjct: 315 YSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLGIQGTFDGSDSILRF 374
Query: 368 KANFAPTIEEFIGEFNLPVSPL 389
K NF I +G FN SP
Sbjct: 375 KQNFNGYIIRKMGTFNYYPSPF 396
>gb|AAC69632.1| factor essential for methicillin resistance FEMA [Staphylococcus
lugdunensis]
Length = 419
Score = 86.7 bits (213), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 92/415 (22%), Positives = 179/415 (43%), Gaps = 48/415 (11%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVM 81
+ + + G+ K+ + + +G+ +V + LL + P+ + Y RGPV+
Sbjct: 20 YSHFTQMTGNYNLKVAEKTETHLVGVKNNNNEVIAACLLTAV-PVMKFFKYFYSNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAA----IKN 137
DY +++LV F L Y K L+++ DP L QY ++ + A A
Sbjct: 79 DYANQELVHFFFNELTKYLKKYNCLYVRIDP-YLPYQY---RDHDGNITANAGNDWFFNK 134
Query: 138 LQEAGVHWTGLTMEIADSIQPRFQANIY----TQENLEMQFPKHTRRLIKDAKQRGVKTY 193
+++ G H G T +Q RF + + T +++ +R K + + GVK
Sbjct: 135 MEQLGYHHDGFTTGFDPILQIRFHSILNLKDKTAKDVLNNMDSLRKRNTKKSSKNGVKVK 194
Query: 194 RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQ 253
+++ EL F + T + K S R++ ++ Y D+ + LA + K D+Y +
Sbjct: 195 FLTEEELPIFRSFMEQTSESKEFSDRDDQFYYNRFKYYKDRVLVPLAYL----KFDEYIE 250
Query: 254 QLILINQDITRTQAHQKKRLKKLEDQKASLERY-------------ITEFEGFTDQYPEE 300
+L Q + + K ++K D K + + + E ++ E
Sbjct: 251 ELTNERQTLEKDLGKALKDIEKRPDNKKAYNKRDNLQQQLDANQQKLNEANQLQAEHGNE 310
Query: 301 V-VVAGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVE 357
+ + AG I N E++Y G + ++ F Y + + A + GI N G+
Sbjct: 311 LPISAGFFII---NPFEVVYYAGGTANKYRHFAGSYAVQWTMINYAIEHGIDRYNFYGIS 367
Query: 358 GSLDD-----GLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQLKNK 406
G+ D G+ +FK + + E++G+F P++ P+Y +Y + K+++NK
Sbjct: 368 GNFSDDAEDAGVIRFKKGYGAEVIEYVGDFVKPINKPMY----KLYSVLKRIQNK 418
>ref|NP_764612.1| methicillin resistance factor [Staphylococcus epidermidis ATCC
12228]
ref|YP_188524.1| femA protein [Staphylococcus epidermidis RP62A]
sp|Q5HPG6|FEMA_STAEQ Aminoacyltransferase femA
sp|Q8CPA9|FEMA_STAES Aminoacyltransferase femA
gb|AAO04654.1|AE016747_151 methicillin resistance factor [Staphylococcus epidermidis ATCC
12228]
gb|AAW54349.1| femA protein [Staphylococcus epidermidis RP62A]
Length = 417
Score = 86.7 bits (213), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 94/410 (22%), Positives = 182/410 (44%), Gaps = 44/410 (10%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + ++G+ K+ ++ +GI + +V + LL +P+ + Y RGPV+
Sbjct: 20 YSHFTQMEGNYELKVAEGTESHLVGIKNNDNEVIAACLLTA-VPVMKIFKYFYSNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALA--AIKNLQ 139
DY +++LV F L Y K L+++ DP L QY L E E A L+
Sbjct: 79 DYNNKELVHFFFNELSKYVKKYNCLYLRVDP-YLPYQY-LNHEGEITGNAGHDWIFDELE 136
Query: 140 EAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYR----- 194
G G +Q R+ + + NL + + + ++R K +
Sbjct: 137 SLGYKHEGFHKGFDPVLQIRYHSVL----NLANKSANDVLKNMDGLRKRNTKKVKKNGVK 192
Query: 195 ---VSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQY 251
+S+ EL F + T + K+ + R ++++ Y D+ + LA +N + +++
Sbjct: 193 VRFLSEEELPIFRSFMEDTSETKDFADREDSFYYNRFKHYKDRVLVPLAYINFDEYIEEL 252
Query: 252 RQQLILINQDITRT-----------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ ++N+D + +AH KK + LE Q + ++ I E + ++ E
Sbjct: 253 NNERNVLNKDYNKALKDIEKRPENKKAHNKK--ENLEQQLDANQQKINEAKNLKQEHGNE 310
Query: 301 V-VVAGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVE 357
+ + AG I N E++Y G ++ ++ F Y + + A + GI N G+
Sbjct: 311 LPISAGFFII---NPFEVVYYAGGTSNRYRHFAGSYAVQWKMINYAIEHGINRYNFYGIS 367
Query: 358 GSL-----DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRK 401
G D G+ KFK + + E++G+F P++ P+Y+I T+ K++K
Sbjct: 368 GDFSEDAEDAGVVKFKKGYDADVIEYVGDFIKPINKPMYNIYRTLKKLKK 417
>ref|YP_602023.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10750]
gb|ABF37479.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10750]
Length = 411
Score = 86.3 bits (212), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 109/425 (25%), Positives = 189/425 (44%), Gaps = 40/425 (9%)
Query: 8 AKIGISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKE-EKQVASLSLLIK 64
A I IS+E+ D + S +Q S+ A + K + + +G+ K+ E +VA++ K
Sbjct: 2 ALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLGLEKDGELKVAAMVFSQK 61
Query: 65 LLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
+ G + + GP ++ + +L F + LKDY K K + ++LK Y Q
Sbjct: 62 VA--GGWRMELNAGPNTNHPE-ELEHFYTQ-LKDYAKQKDVI------ELILKPYDNYQS 111
Query: 125 EEEKPLALAA-----IKNLQEAGVHWTGLTMEIADSIQPRF----QANIYTQENLEMQFP 175
+ + ++ I L G GL + +P + + +L F
Sbjct: 112 FDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEG-EPVWHYVKKLEGIDSSHLTHSFS 170
Query: 176 KHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKA 235
K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q ++GD
Sbjct: 171 KKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYDSFGDSC 230
Query: 236 YLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQKASLERY 286
+A +N L+ +Q+ + + I + + H +K RLK+L Q + +
Sbjct: 231 EFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVR 290
Query: 287 ITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
I+E F ++Y ++V +AG L I L++G F KFY LL + A
Sbjct: 291 ISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIH 350
Query: 346 DGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMYKIRKQ 402
GI N G+ G D DG+ +FK NF I + G F P+ YH ++ K+
Sbjct: 351 KGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFKCYPFPIKYHFI----RLAKK 406
Query: 403 LKNKH 407
L N++
Sbjct: 407 LLNRY 411
>ref|ZP_00366261.1| COG2348: Uncharacterized protein involved in methicillin resistance
[Streptococcus pyogenes M49 591]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 109/425 (25%), Positives = 189/425 (44%), Gaps = 40/425 (9%)
Query: 8 AKIGISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKE-EKQVASLSLLIK 64
A I IS+E+ D + + S +Q S+ A + K + + +G+ K+ E +VA++ K
Sbjct: 2 ALIEISQEQFDHYCHSLVRHSFIQTSEMASLMAKRGAKPQFLGLEKDGELKVAAMVFSQK 61
Query: 65 LLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
+ G + + GP ++ + +L F + LKDY K K + ++LK Y Q
Sbjct: 62 VA--GGWRMELNAGPNTNHPE-ELEHFYTQ-LKDYAKQKDVI------ELILKPYDNYQS 111
Query: 125 EEEKPLALAA-----IKNLQEAGVHWTGLTMEIADSIQPRF----QANIYTQENLEMQFP 175
+ + ++ I L G GL + +P + + L F
Sbjct: 112 FDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEG-EPVWHYVKKLEGIDSSRLTHSFS 170
Query: 176 KHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKA 235
K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q ++GD
Sbjct: 171 KKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYDSFGDSC 230
Query: 236 YLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQKASLERY 286
+A +N L+ +Q+ + + I + + H +K RLK+L Q + +
Sbjct: 231 EFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVR 290
Query: 287 ITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
I+E F ++Y ++V +AG L I L++G F KFY LL + A
Sbjct: 291 ISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIH 350
Query: 346 DGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMYKIRKQ 402
GI N G+ G D DG+ +FK NF I + G F P+ YH ++ K+
Sbjct: 351 KGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI----RLAKK 406
Query: 403 LKNKH 407
L N++
Sbjct: 407 LLNRY 411
>ref|NP_268867.1| putative peptidoglycan branched peptide synthesis protein, alanine
adding enzyme [Streptococcus pyogenes M1 GAS]
ref|YP_281873.1| factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS5005]
gb|AAK33588.1| putative peptidoglycan branched peptide synthesis protein, alanine
adding enzyme [Streptococcus pyogenes M1 GAS]
gb|AAZ51128.1| factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS5005]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/251 (28%), Positives = 117/251 (46%), Gaps = 17/251 (6%)
Query: 170 LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMT 229
L F K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q
Sbjct: 165 LTRSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYD 224
Query: 230 TYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQK 280
++GD +A +N L+ +Q+ + + I + + H +K RLK+L Q
Sbjct: 225 SFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQF 284
Query: 281 ASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ + I+E F ++Y ++V +AG L I L++G F KFY LL +
Sbjct: 285 ETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHA 344
Query: 340 FQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTM 396
A GI N G+ G D DG+ +FK NF I + G F P+ YH
Sbjct: 345 MLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI--- 401
Query: 397 YKIRKQLKNKH 407
++ K+L N++
Sbjct: 402 -RLAKKLLNRY 411
>ref|YP_279958.1| methicillin resistance expression factor [Streptococcus pyogenes
MGAS6180]
gb|AAX71603.1| methicillin resistance expression factor [Streptococcus pyogenes
MGAS6180]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/251 (28%), Positives = 117/251 (46%), Gaps = 17/251 (6%)
Query: 170 LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMT 229
L F K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q
Sbjct: 165 LTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYD 224
Query: 230 TYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQK 280
++GD +A +N L+ +Q+ + + I + + H +K RLK+L Q
Sbjct: 225 SFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQF 284
Query: 281 ASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ + I+E F ++Y ++V +AG L I L++G F KFY LL +
Sbjct: 285 ETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHA 344
Query: 340 FQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTM 396
A GI N G+ G D DG+ +FK NF I + G F P+ YH
Sbjct: 345 MLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI--- 401
Query: 397 YKIRKQLKNKH 407
++ K+L N++
Sbjct: 402 -RLAKKLLNRY 411
>ref|NP_664238.1| putative peptidoglycan branched peptide synthesis protein, alanine
adding enzyme [Streptococcus pyogenes MGAS315]
ref|NP_802683.1| putative peptidoglycan branched peptide synthesis protein, alanine
adding enzyme [Streptococcus pyogenes SSI-1]
gb|AAM79041.1| putative peptidoglycan branched peptide synthesis protein, alanine
adding enzyme [Streptococcus pyogenes MGAS315]
dbj|BAC64516.1| putative peptidoglycan branched peptide synthesis protein, alanine
adding enzyme [Streptococcus pyogenes SSI-1]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/251 (28%), Positives = 117/251 (46%), Gaps = 17/251 (6%)
Query: 170 LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMT 229
L F K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q
Sbjct: 165 LTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYD 224
Query: 230 TYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQK 280
++GD +A +N L+ +Q+ + + I + + H +K RLK+L Q
Sbjct: 225 SFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQF 284
Query: 281 ASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ + I+E F ++Y ++V +AG L I L++G F KFY LL +
Sbjct: 285 ETFQVRISEALHFLEEYGTKDVFLAGSLFIYTKQEAVYLFSGSYPKFNKFYSPALLQEHA 344
Query: 340 FQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTM 396
A GI N G+ G D DG+ +FK NF I + G F P+ YH
Sbjct: 345 MLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI--- 401
Query: 397 YKIRKQLKNKH 407
++ K+L N++
Sbjct: 402 -RLAKKLLNRY 411
>ref|YP_059849.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10394]
ref|YP_598113.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10270]
ref|YP_001128894.1| putative peptidoglycan branched peptide synthesis protein
[Streptococcus pyogenes str. Manfredo]
gb|AAT86666.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10394]
gb|ABF33569.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS10270]
emb|CAM30681.1| putative peptidoglycan branched peptide synthesis protein
[Streptococcus pyogenes str. Manfredo]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/251 (28%), Positives = 117/251 (46%), Gaps = 17/251 (6%)
Query: 170 LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMT 229
L F K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q
Sbjct: 165 LTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYD 224
Query: 230 TYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQK 280
++GD +A +N L+ +Q+ + + I + + H +K RLK+L Q
Sbjct: 225 SFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQF 284
Query: 281 ASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ + I+E F ++Y ++V +AG L I L++G F KFY LL +
Sbjct: 285 ETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHA 344
Query: 340 FQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTM 396
A GI N G+ G D DG+ +FK NF I + G F P+ YH
Sbjct: 345 MLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI--- 401
Query: 397 YKIRKQLKNKH 407
++ K+L N++
Sbjct: 402 -RLAKKLLNRY 411
>ref|YP_596232.1| factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS9429]
ref|YP_600118.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS2096]
gb|ABF31688.1| factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS9429]
gb|ABF35574.1| Factor essential for expression of methicillin resistance
[Streptococcus pyogenes MGAS2096]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/251 (28%), Positives = 117/251 (46%), Gaps = 17/251 (6%)
Query: 170 LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMT 229
L F K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q
Sbjct: 165 LTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYD 224
Query: 230 TYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQK 280
++GD +A +N L+ +Q+ + + I + + H +K RLK+L Q
Sbjct: 225 SFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQF 284
Query: 281 ASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ + I+E F ++Y ++V +AG L I L++G F KFY LL +
Sbjct: 285 ETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHA 344
Query: 340 FQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTM 396
A GI N G+ G D DG+ +FK NF I + G F P+ YH
Sbjct: 345 MLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI--- 401
Query: 397 YKIRKQLKNKH 407
++ K+L N++
Sbjct: 402 -RLAKKLLNRY 411
>ref|ZP_01820381.1| beta-lactam resistance factor [Streptococcus pneumoniae SP6-BS73]
ref|ZP_01829465.1| beta-lactam resistance factor [Streptococcus pneumoniae SP18-BS74]
ref|ZP_01832137.1| beta-lactam resistance factor [Streptococcus pneumoniae SP19-BS75]
ref|ZP_02707800.1| alanine-adding enzyme MurN [Streptococcus pneumoniae CDC1873-00]
ref|YP_001835293.1| beta-lactam resistance factor [Streptococcus pneumoniae CGSP14]
gb|AAY56877.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
gb|AAY56878.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
gb|EDK69626.1| beta-lactam resistance factor [Streptococcus pneumoniae SP18-BS74]
gb|EDK72176.1| beta-lactam resistance factor [Streptococcus pneumoniae SP19-BS75]
gb|EDK76555.1| beta-lactam resistance factor [Streptococcus pneumoniae SP6-BS73]
gb|EDT51750.1| alanine-adding enzyme MurN [Streptococcus pneumoniae CDC1873-00]
gb|ACB89828.1| beta-lactam resistance factor [Streptococcus pneumoniae CGSP14]
Length = 410
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 166/364 (45%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + ++L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>ref|NP_606857.1| putative peptidoglycan branched peptide synthesis protein alanine
adding enzyme [Streptococcus pyogenes MGAS8232]
gb|AAL97356.1| putative peptidoglycan branched peptide synthesis protein alanine
adding enzyme [Streptococcus pyogenes MGAS8232]
Length = 411
Score = 86.3 bits (212), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/251 (28%), Positives = 118/251 (47%), Gaps = 17/251 (6%)
Query: 170 LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMT 229
L F K + LIK A G+K ++ + ELH F +I T R++ ++ +Y+Q
Sbjct: 165 LTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYD 224
Query: 230 TYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQA------HQKK---RLKKLEDQK 280
++GD +A +N L+ +Q+ + + I + + H +K RLK+L Q
Sbjct: 225 SFGDSCEFIVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQF 284
Query: 281 ASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNV 339
+ + I+E F ++Y ++V +AG L I L++G F KFY LL +
Sbjct: 285 ETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHA 344
Query: 340 FQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTM 396
A GI N G+ G+ D DG+ +FK NF I + G F P+ YH
Sbjct: 345 MLKAIHKGIKQYNFLGITGNFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFI--- 401
Query: 397 YKIRKQLKNKH 407
++ K+L N++
Sbjct: 402 -RLAKKLLNRY 411
>emb|CAB89538.1| MurN protein [Streptococcus pneumoniae]
Length = 410
Score = 85.9 bits (211), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 93/369 (25%), Positives = 166/369 (44%), Gaps = 30/369 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + I GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMEINSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIANTMYK 398
+ A + K
Sbjct: 397 KYKAIQLLK 405
>gb|AAY56883.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
Length = 410
Score = 85.9 bits (211), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 103/415 (24%), Positives = 190/415 (45%), Gaps = 35/415 (8%)
Query: 8 AKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIY---KEEKQVASLSLLIK 64
A I +++EE ++ + S +Q + + + RI +Y K+E ++ +L+
Sbjct: 2 ALITLTKEEFQAYSGQVSSRSFMQSVQMGDLLEK-RGARI-VYLALKQEGEIQVAALVYS 59
Query: 65 LLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ- 123
L LG + I GP+ Y +D + LK+Y K L +L+K Y Q
Sbjct: 60 LPMLGGLHMEINSGPI--YTQQDALPVFYAELKEYAKQNGVL------ELLVKPYETYQT 111
Query: 124 -EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIA----DSIQPRFQANIYTQENLEMQFP 175
+ + P+ + I+ L + G + GLT D + + A + T+++L F
Sbjct: 112 FDIQGNPIDAEKKSMIQGLTDLGYQFDGLTRGYPGGEPDWLYYKDLAEL-TEKSLLKSFS 170
Query: 176 KHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKA 235
K + L+K A+ G++ ++ + EL F I T +R+ S ++ Y++ T+G++A
Sbjct: 171 KKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQA 230
Query: 236 YLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--RLKKLEDQKASLERY 286
+A +N + + + + ++L + D+++ +KK +L++ Q + E
Sbjct: 231 EFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVR 290
Query: 287 ITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
E ++Y EE +V+AG L + L++G +F KFY LL V ++ +
Sbjct: 291 KAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIK 350
Query: 346 DGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYK 398
GI N G++G D DG+ +FK NF I G F SPL + A + K
Sbjct: 351 RGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLK 405
>ref|ZP_01825758.1| beta-lactam resistance factor [Streptococcus pneumoniae SP11-BS70]
ref|ZP_02722359.1| beta-lactam resistance factor [Streptococcus pneumoniae MLV-016]
gb|EDK62976.1| beta-lactam resistance factor [Streptococcus pneumoniae SP11-BS70]
gb|EDT98223.1| beta-lactam resistance factor [Streptococcus pneumoniae MLV-016]
Length = 410
Score = 85.9 bits (211), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 165/364 (45%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I++L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKL-------DQYRQQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + ++ + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>ref|ZP_01817315.1| beta-lactam resistance factor [Streptococcus pneumoniae SP3-BS71]
ref|ZP_01822000.1| beta-lactam resistance factor [Streptococcus pneumoniae SP9-BS68]
gb|EDK75255.1| beta-lactam resistance factor [Streptococcus pneumoniae SP3-BS71]
gb|EDK79915.1| beta-lactam resistance factor [Streptococcus pneumoniae SP9-BS68]
Length = 410
Score = 85.5 bits (210), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 165/364 (45%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>gb|AAD45258.1|AF145332_1 methicillin resistance protein FemA [Staphylococcus gallinarum]
Length = 420
Score = 85.5 bits (210), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 88/406 (21%), Positives = 178/406 (43%), Gaps = 28/406 (6%)
Query: 18 DSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYI 75
DS H + + G+ KI + +GI E +V + LL + P+ + Y
Sbjct: 16 DSMPNSH--FTQMVGNYELKIAEGTETHLVGIKNNENEVIAACLLTAV-PVMKYFKYFYT 72
Query: 76 PRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAI 135
RGPV+D+ +++LV + L Y K +AL+++ DP + + + E
Sbjct: 73 NRGPVIDFENKELVHYFFNELSKYVKKHRALYLRVDPYLPYQYRNHDGDVLENAGHDWIF 132
Query: 136 KNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHT----RRLIKDAKQRGVK 191
++ G G +Q RF + + ++ + K +R K ++ GVK
Sbjct: 133 DKMKHLGYKHQGFLTGFDPVVQIRFHSVLELKDKTDKDVLKDMDGLRKRNTKKVQKNGVK 192
Query: 192 TYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQY 251
+ + EL F + T + K R+++++ + Y ++ + LA ++ + +++
Sbjct: 193 VRFLGEDELPIFRAFMEDTSETKAFEDRDDSFYYNRLKYYKNRVLVPLAYMDFDEYIEEL 252
Query: 252 RQQLILINQDITRTQAHQKKRL--KKLEDQKASLERY-------ITEFEGFTDQYPEEVV 302
+ ++++DI + +KR KK +++ +LE+ I E + Q+ E+
Sbjct: 253 TAEREVLSKDINKALKDIEKRPENKKAYNKRDNLEKQLIANQQKIDEAKALQKQHGNELP 312
Query: 303 VAGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
++ I N E++Y G +++F+ F Y + + A + I N G+ G
Sbjct: 313 ISAAFFII--NPYEVVYYAGGTSNEFRHFAGSYAVQWTMINYALDNNIDRYNFYGISGDF 370
Query: 361 -----DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIR 400
D G+ KFK F + E++G+F P++ P Y I + K++
Sbjct: 371 TEDAEDAGVVKFKKGFNADVIEYVGDFIKPINRPAYKIYTALKKLK 416
>ref|ZP_01835631.1| beta-lactam resistance factor [Streptococcus pneumoniae SP23-BS72]
gb|EDK81257.1| beta-lactam resistance factor [Streptococcus pneumoniae SP23-BS72]
Length = 410
Score = 85.5 bits (210), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 92/369 (24%), Positives = 167/369 (45%), Gaps = 30/369 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT+ +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTIGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIANTMYK 398
+ A + K
Sbjct: 397 KYKAIQLLK 405
>ref|NP_345128.1| beta-lactam resistance factor [Streptococcus pneumoniae TIGR4]
ref|ZP_01408291.1| hypothetical protein SpneT_02001252 [Streptococcus pneumoniae
TIGR4]
emb|CAB89121.1| beta-lactam resistance factor [Streptococcus pneumoniae]
gb|AAK74768.1| beta-lactam resistance factor [Streptococcus pneumoniae TIGR4]
Length = 410
Score = 85.5 bits (210), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 165/364 (45%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I++L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>ref|YP_329990.1| beta-lactam resistance factor [Streptococcus agalactiae A909]
gb|ABA44921.1| beta-lactam resistance factor [Streptococcus agalactiae A909]
Length = 411
Score = 85.1 bits (209), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 73/270 (27%), Positives = 123/270 (45%), Gaps = 15/270 (5%)
Query: 135 IKNLQEAGVHWTGLTMEIADS-IQPRFQANI--YTQENLEMQFPKHTRRLIKDAKQRGVK 191
I++ +G H GLT + + N+ T E L F K R L+K A G+K
Sbjct: 127 IEDFTSSGYHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKAMSFGIK 186
Query: 192 TYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ----- 246
+ + ELH F +I + T R++ ++ Y+Q ++ KA +A +N +
Sbjct: 187 VRVLKRDELHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFREYDHNL 246
Query: 247 --KLDQYRQQLILINQDITRTQAHQKKRLKKLE--DQKASLERYITEFEGFTDQYP-EEV 301
K + +L L+++ K ++ E +Q AS E E + F +Y ++V
Sbjct: 247 QIKAEALENKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQKYDNQDV 306
Query: 302 VVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD 361
V+AG L + ++G +F KFY +L V Q+A + G + N+ G++G+ D
Sbjct: 307 VLAGSLFVYSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLGIQGTFD 366
Query: 362 --DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
D + +FK NF I +G FN SP
Sbjct: 367 GSDSILRFKQNFNGYIIRKMGTFNYYPSPF 396
>ref|NP_358135.1| Alanine adding enzyme [Streptococcus pneumoniae R6]
ref|YP_816037.1| beta-lactam resistance factor [Streptococcus pneumoniae D39]
ref|ZP_02714641.1| alanine adding enzyme [Streptococcus pneumoniae CDC0288-04]
ref|ZP_02716920.1| alanine adding enzyme [Streptococcus pneumoniae CDC3059-06]
emb|CAB89536.1| MurN protein [Streptococcus pneumoniae]
gb|AAK99345.1| Alanine adding enzyme [Streptococcus pneumoniae R6]
emb|CAC80803.1| MurN protein [Streptococcus pneumoniae]
gb|AAY56876.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
gb|AAY56879.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
gb|AAY56882.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
gb|ABJ53607.1| beta-lactam resistance factor [Streptococcus pneumoniae D39]
gb|EDT95559.1| alanine adding enzyme [Streptococcus pneumoniae CDC0288-04]
gb|EDT97537.1| alanine adding enzyme [Streptococcus pneumoniae CDC3059-06]
Length = 410
Score = 85.1 bits (209), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 164/364 (45%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>gb|AAD33942.1|AF144663_1 factor essential for methicillin resistance [Staphylococcus
warneri]
Length = 418
Score = 84.7 bits (208), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 95/410 (23%), Positives = 177/410 (43%), Gaps = 42/410 (10%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + + G+ K+ ++ +GI + +V + LL + P+ + Y RGPV+
Sbjct: 20 YTHFTQMVGNYELKLAEGTESHLVGIKNNDNEVIAACLLTAV-PVMKFFKYFYTNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY------ALGQEEEEKPLALAAI 135
DY +++LV F L Y K L+++ DP L QY G + A
Sbjct: 79 DYDNKELVHFFFNELSKYVKKHHCLYLRVDP-YLPYQYRNHDGDITGNAGNDWIFDKLAS 137
Query: 136 KNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHT--------RRLIKDAKQ 187
+ G H + P Q ++ NL+ + K +R K ++
Sbjct: 138 LGFKHEGFH---------NGFDPILQVRHHSVLNLKGKTAKDVLNDMDNLRKRNTKKVQK 188
Query: 188 RGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQK 247
GVK +S+ EL F + T + K R+++Y+ + D+ + LA +N +
Sbjct: 189 NGVKVKFLSEDELPIFRSFMEDTSESKAFLDRDDSYYYDRYKHFKDRVLVPLAYINFDEY 248
Query: 248 LDQYRQQLILINQDITRTQAHQKKRL--KKLEDQKASLERYITEFEGFTDQYPEEVVVAG 305
L++ + + +D+ + +KR KK ++KA+LE+ + + D+ + G
Sbjct: 249 LEELNNEKETLTKDLNKALKDIEKRPDNKKSHNKKANLEQQLAANQQKIDEAKQLQAEHG 308
Query: 306 I-LSISYG----NVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG 358
L IS G N E++Y G ++ ++ F Y + + A GI N G+ G
Sbjct: 309 NELPISAGYFFINPFEVVYYAGGTSNKYRHFAGSYAVQWTMINYALDHGIDRYNFYGISG 368
Query: 359 SL-----DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQ 402
D G+ KFK + + E++G+F P++ P+Y + T+ K+ K+
Sbjct: 369 DFSEDAEDAGVIKFKKGYNADVIEYVGDFIKPINKPMYTVYTTLKKLLKK 418
>ref|YP_519925.1| hypothetical protein DSY3692 [Desulfitobacterium hafniense Y51]
dbj|BAE85481.1| hypothetical protein [Desulfitobacterium hafniense Y51]
Length = 375
Score = 84.7 bits (208), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 91/422 (21%), Positives = 175/422 (41%), Gaps = 85/422 (20%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLI--KLLPLG 69
ISEE + +F+ + + +Q WAK+K +W ++ +G + + ++A L++ K+ L
Sbjct: 7 ISEETYYAFISQADLGNFMQYPSWAKVKTEWTSDLLGWFTPDNKLAGCGLILYRKMPCLN 66
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA-------LG 122
R + Y PRGP++D+ +L + + L Y ++K+ IK DP ++ +++ LG
Sbjct: 67 RYLAYCPRGPLIDWQSPNLREW-FEPLVAYLRSKQVFSIKIDPPVVQAKWSAPTIKTFLG 125
Query: 123 QEEEE----------KPLALAAIKNLQEAGVHWTGLTMEIADS----IQPRFQANIYTQ- 167
Q E+ P + + G + D+ QP++ + +
Sbjct: 126 QAREQGSKGKVLRDLPPDEDYTTVQQVQQQLRQMGWRKQRGDTGFAATQPQYVYRLPLEG 185
Query: 168 ---ENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYF 224
E + F + RR +K A++ GVK ++ +L F +++ +T +R + +R+ +YF
Sbjct: 186 RSLEEVFAGFHTNWRRNVKKAERLGVKVRVGTEQDLPAFYELLKVTSERDHFKVRSFSYF 245
Query: 225 QKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLE 284
L YR + +A + L ED
Sbjct: 246 SNL-----------------------YRS---------LKAEAADRIALYLAED------ 267
Query: 285 RYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAY 344
EE ++A L++ LY ++ ++ P + + + QDAY
Sbjct: 268 --------------EEELLAATLAVHSNAHSWYLYGASSNVKREKAPNHAIQWRMIQDAY 313
Query: 345 QDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKI 399
Q + G+ +LD+ GL +FK F E I ++ P+ PL + A +Y
Sbjct: 314 QLKAYTYDFRGISPTLDESDPLFGLLRFKLGFGGEACEMISAWDYPLQPLLYRAFQLYLK 373
Query: 400 RK 401
R+
Sbjct: 374 RR 375
>gb|AAY56880.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
Length = 410
Score = 84.7 bits (208), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 101/415 (24%), Positives = 186/415 (44%), Gaps = 35/415 (8%)
Query: 8 AKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIY---KEEKQVASLSLLIK 64
A I +++EE ++ + S +Q + + + RI +Y K+E ++ +L+
Sbjct: 2 ALITLTKEEFQAYSGQVSSRSFMQSVQMGDLLEK-RGARI-VYLALKQEGEIQVAALVYS 59
Query: 65 LLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQ- 123
L LG + + GP+ Y +D + LK+Y K L +L+K Y Q
Sbjct: 60 LPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL------ELLVKPYETYQT 111
Query: 124 -EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----QANIYTQENLEMQFP 175
+ + P+ + I+ L + G + GLT +P + T+++L F
Sbjct: 112 FDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKDLTELTEKSLLKSFS 170
Query: 176 KHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKA 235
K + L+K A+ G++ ++ + EL F I T +R+ S ++ Y++ T+G++A
Sbjct: 171 KKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQA 230
Query: 236 YLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--RLKKLEDQKASLERY 286
+A +N + + + + L + D+++ +KK +L++ Q + E
Sbjct: 231 EFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVR 290
Query: 287 ITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
E ++Y EE +V+AG L + L++G +F KFY LL V ++ +
Sbjct: 291 KAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIK 350
Query: 346 DGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYK 398
GI N G++G D DG+ +FK NF I G F SPL + A + K
Sbjct: 351 RGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLK 405
>ref|ZP_01827238.1| beta-lactam resistance factor [Streptococcus pneumoniae SP14-BS69]
gb|EDK66602.1| beta-lactam resistance factor [Streptococcus pneumoniae SP14-BS69]
Length = 410
Score = 84.7 bits (208), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 165/364 (45%), Gaps = 30/364 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-KPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + + L + D+++ +KK +
Sbjct: 217 EYYEYFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFCYHPSPL 396
Query: 390 YHIA 393
+ A
Sbjct: 397 KYKA 400
>ref|ZP_00121083.2| COG2348: Uncharacterized protein involved in methicillin resistance
[Bifidobacterium longum DJO10A]
Length = 411
Score = 84.7 bits (208), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 89/414 (21%), Positives = 178/414 (42%), Gaps = 27/414 (6%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSD---WAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
I+ EE D + Q S Q S AKI+ + E +G+ + + +++ L
Sbjct: 2 ITPEELDRLSEATSQGSFQQWSGQVRLAKIRGH-EAECVGVCDASGNLVTGCVILYLNGR 60
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
+ + GP+ D L+ + +++ + A+ + P + + Y+ + + +
Sbjct: 61 FGADGSVYFGPIGISDDPALLRAITEAIRESARRHHAVSVACWPNVAYRLYSSDGQPDGE 120
Query: 129 P----LALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKD 184
P LA A G H TG + + + + I + L F K + +K
Sbjct: 121 PNDALLAGFADAGWMHGGFH-TGYDV-VCQWMYVKDLTGITNGKELLASFGKRAQWSVKR 178
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
A+ GV + E F+ I T +R+ + R YF++ YG A+ LA+++I
Sbjct: 179 AQSMGVHVREIGPDEFDVFADIERRTGERRGFATRGADYFRQFKQAYGADAHFMLAEIHI 238
Query: 245 PQKLDQYRQQLILINQDITRTQAHQKKR-LKKLEDQ-------KASLERYITEFEGFTDQ 296
+ + + + + R QA +R ++E Q A+ ++ + E EG+ +
Sbjct: 239 AEYVADMTAKREALQAKVARLQAKYDERPTTRIERQLGEESRNLAAADKRLAEVEGYARK 298
Query: 297 YPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLL-YPNVFQDAYQDGIIWANMGG 355
+ + A + +S+ N + Y+G +++K FY L+ Y + + G+ N G
Sbjct: 299 -GDVLPAAASMFVSHPNEVVYQYSGSLEEYKPFYASALIQYEAMLHLCVEKGVPRYNFYG 357
Query: 356 VEGSLDD------GLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMYKIRKQ 402
+ G DD G+ +FK F +E+ +G+F LPV + ++N +K+ ++
Sbjct: 358 ISGVFDDPDDEGRGVLEFKQGFNGYVEQMVGKFTLPVDKFRFGVSNLAHKLLRR 411
>ref|ZP_01544461.1| hypothetical protein, FemAB family [Oenococcus oeni ATCC BAA-1163]
gb|EAV39286.1| hypothetical protein, FemAB family [Oenococcus oeni ATCC BAA-1163]
Length = 422
Score = 84.0 bits (206), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 90/403 (22%), Positives = 173/403 (42%), Gaps = 42/403 (10%)
Query: 16 EHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLI-KLLPLGRSI 72
E+ +F H Q + +Q ++ + K +G+ + +V + +L+ + LG ++
Sbjct: 12 EYANFENNHPQGNFVQSAEQKSLLEKRGENAALVGLKDDTGKVVAGALVTWAKVKLG-NL 70
Query: 73 IYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA-----LGQEEE- 126
I RGP++DY + L+ + L + K + LFI+ P I +Y +G +
Sbjct: 71 FSIERGPLLDYSNEQLIKAFISGLTVFSKKRDGLFIRIRPNIAYAKYTERGKLIGDKNTT 130
Query: 127 --EKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ----ANIYTQENLEMQFPKHTRR 180
EK +LAA L + G + S +P +Q E++ + + +
Sbjct: 131 FVEKLNSLAADHQLPQIG---------FSTSCEPEWQFVKDLTEVDPEHVVKSYNRQAKY 181
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
+ KQ +K ++ + EL F +I T R + ++ +++ L TYG KA A
Sbjct: 182 HLNKNKQFCIKLRKIGRDELPAFKRITQQTADRLHYHDKSLDFYETLFDTYGKKAKFIFA 241
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQY 297
++N + + + L I + +T + L D AS +R+++E E +
Sbjct: 242 EINFKEYSESIEKDLNDIQKKLTEIAGADYHNISDLSDFSASAKRHLSEGIKTETALQKR 301
Query: 298 PEE------------VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
+E V+V+ L + + LY+G ++ ++ + Y + + +A +
Sbjct: 302 LQEAKKMHQEAKHDIVLVSVALFVIENQEVVYLYSGSDEKYEHLFAPYEIQDTMITEAVK 361
Query: 346 DGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPV 386
+ I N GV G D DG+ FK +F E +G F+ PV
Sbjct: 362 ERIPLYNFYGVSGKFDGSDGVLGFKTHFNGYTREMVGSFDFPV 404
>sp|P95734|FEMA_STAEP Aminoacyltransferase femA
Length = 417
Score = 83.6 bits (205), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 93/410 (22%), Positives = 181/410 (44%), Gaps = 44/410 (10%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + ++G+ K+ ++ +GI + +V + LL +P+ + Y RGPV+
Sbjct: 20 YSHFTQMEGNYELKVAEGTESHLVGIKNNDNEVIAACLLTA-VPVMKIFKYFYSNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALA--AIKNLQ 139
DY +++LV F L Y K L+++ DP L QY L E E A L+
Sbjct: 79 DYNNKELVHFFFNELSKYVKKYNCLYLRVDP-YLPYQY-LNHEGEITGNAGHDWIFDELE 136
Query: 140 EAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYR----- 194
G G +Q R+ + + NL + + + ++R K +
Sbjct: 137 SLGYKHEGFHKGFDPVLQIRYHSVL----NLANKSANDVLKNMDGLRKRNTKKVKKNGVK 192
Query: 195 ---VSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQY 251
+S+ EL F + T + K+ + R ++++ Y + + LA +N + +++
Sbjct: 193 VRFLSEEELPIFRSFMEDTSETKDFADREDSFYYNRFKHYKGRVLVPLAYINFDEYIEEL 252
Query: 252 RQQLILINQDITRT-----------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ ++N+D + +AH KK + LE Q + ++ I E + ++ E
Sbjct: 253 NNERNVLNKDYNKALKDIEKRPENKKAHNKK--ENLEQQLDANQQKINEAKNLKQEHGNE 310
Query: 301 V-VVAGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVE 357
+ + AG I N E++Y G ++ ++ F Y + + A + GI N G+
Sbjct: 311 LPISAGFFII---NPFEVVYYAGGTSNRYRHFAGSYAVQWKMINYAIEHGINRYNFYGIS 367
Query: 358 GSL-----DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRK 401
G D G+ KFK + + E++G+F P++ P+Y+I T+ K++K
Sbjct: 368 GDFSEDAEDAGVVKFKKGYDADVIEYVGDFIKPINKPMYNIYRTLKKLKK 417
>gb|AAB41947.1| FEMA [Staphylococcus epidermidis]
Length = 422
Score = 83.6 bits (205), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 93/410 (22%), Positives = 181/410 (44%), Gaps = 44/410 (10%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGR--SIIYIPRGPVM 81
+ + ++G+ K+ ++ +GI + +V + LL +P+ + Y RGPV+
Sbjct: 25 YSHFTQMEGNYELKVAEGTESHLVGIKNNDNEVIAACLLTA-VPVMKIFKYFYSNRGPVI 83
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALA--AIKNLQ 139
DY +++LV F L Y K L+++ DP L QY L E E A L+
Sbjct: 84 DYNNKELVHFFFNELSKYVKKYNCLYLRVDP-YLPYQY-LNHEGEITGNAGHDWIFDELE 141
Query: 140 EAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYR----- 194
G G +Q R+ + + NL + + + ++R K +
Sbjct: 142 SLGYKHEGFHKGFDPVLQIRYHSVL----NLANKSANDVLKNMDGLRKRNTKKVKKNGVK 197
Query: 195 ---VSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQY 251
+S+ EL F + T + K+ + R ++++ Y + + LA +N + +++
Sbjct: 198 VRFLSEEELPIFRSFMEDTSETKDFADREDSFYYNRFKHYKGRVLVPLAYINFDEYIEEL 257
Query: 252 RQQLILINQDITRT-----------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ ++N+D + +AH KK + LE Q + ++ I E + ++ E
Sbjct: 258 NNERNVLNKDYNKALKDIEKRPENKKAHNKK--ENLEQQLDANQQKINEAKNLKQEHGNE 315
Query: 301 V-VVAGILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVE 357
+ + AG I N E++Y G ++ ++ F Y + + A + GI N G+
Sbjct: 316 LPISAGFFII---NPFEVVYYAGGTSNRYRHFAGSYAVQWKMINYAIEHGINRYNFYGIS 372
Query: 358 GSL-----DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRK 401
G D G+ KFK + + E++G+F P++ P+Y+I T+ K++K
Sbjct: 373 GDFSEDAEDAGVVKFKKGYDADVIEYVGDFIKPINKPMYNIYRTLKKLKK 422
>ref|ZP_02710236.1| alanine adding enzyme [Streptococcus pneumoniae CDC1087-00]
gb|EDT91670.1| alanine adding enzyme [Streptococcus pneumoniae CDC1087-00]
Length = 410
Score = 83.2 bits (204), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 91/369 (24%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQEEEEKPLALAA-----IKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + ++ A I+ L + G + GLT +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNSIDAEKKSIIQGLTDLGYQFDGLTTGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ +G++A +A +N + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDIFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIANTMYK 398
+ A + K
Sbjct: 397 KYKAIQLLK 405
>gb|AAY56875.1| alanine-adding enzyme MurN [Streptococcus pneumoniae]
Length = 410
Score = 82.4 bits (202), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 91/369 (24%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKY 110
K+E ++ +L+ L LG + + GP+ Y +D + LK+Y K L
Sbjct: 46 KQEGEIQVAALVYSLPMLGGLHMELNSGPI--YTQQDALPVFYAELKEYAKQNGVL---- 99
Query: 111 DPAILLKQYALGQ--EEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRF----Q 161
+L+K Y Q + + P+ + I+ L + G + GL +P +
Sbjct: 100 --ELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLITGYPGG-EPDWLYYKD 156
Query: 162 ANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNE 221
T+++L F K + L+K A+ G++ ++ + EL F I T +R+ S ++
Sbjct: 157 LTELTEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSL 216
Query: 222 AYFQKLMTTYGDKAYLHLAKVNIPQKLDQYR-------QQLILINQDITRTQAHQKK--R 272
Y++ T+G++A +A +N + + + + L + D+++ +KK +
Sbjct: 217 EYYEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ 276
Query: 273 LKKLEDQKASLERYITEFEGFTDQYPEE-VVVAGILSISYGNVMEMLYAGMNDDFKKFYP 331
L++ Q + E E ++Y EE +V+AG L + L++G +F KFY
Sbjct: 277 LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYA 336
Query: 332 QYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
LL V ++ + GI N G++G D DG+ +FK NF I G F SPL
Sbjct: 337 PALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPL 396
Query: 390 YHIANTMYK 398
+ A + K
Sbjct: 397 KYKAIQLLK 405
>ref|NP_628090.1| hypothetical protein SCO3904 [Streptomyces coelicolor A3(2)]
emb|CAB42732.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]
Length = 373
Score = 82.4 bits (202), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 90/421 (21%), Positives = 173/421 (41%), Gaps = 86/421 (20%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKE---EKQVASLSLLIKLLPL 68
IS E+H ++++ S +Q WA +K +W++E +G + + E A L L +L +
Sbjct: 8 ISREQHLAYIQSLPAASHMQVPAWADVKAEWRSENLGWFDDRTGELVGAGLVLYRQLPKI 67
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
R + Y+P GPV+++ +L + M+ + + K + A +K P ++++++ +K
Sbjct: 68 KRYLAYLPEGPVINWFAPNLQDW-MEPMLAHLKQQGAFSVKMGPPVIIRRW--DATSIKK 124
Query: 129 PLALAAIKNLQEAGV-HWTGLTMEIAD------------------SIQPR--FQANIYTQ 167
+ +K L++ H E+AD +QPR FQ + +
Sbjct: 125 GIQDPDVKRLRDIEADHIEPRAFEVADKLRRMGWQQGEDGGAGFGDVQPRYVFQVPLANR 184
Query: 168 --ENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQ 225
E + F + RR IK A++ GV+ + +L ++ ++ +T R + R +YFQ
Sbjct: 185 SLEEVHKNFNQLWRRNIKKAEKAGVEVVQGGYHDLEEWQRLYEITAVRDHFRPRPLSYFQ 244
Query: 226 KLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLER 285
++ L N+D R +
Sbjct: 245 RMWAA--------------------------LNNEDPNR------------------MRL 260
Query: 286 YITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
Y G +VV G + SYG ++ ++ P + + +D+Y
Sbjct: 261 YFARHNGVNLSAATMLVVGGHVWYSYG--------ASDNIGREVRPSNAMQWAMLRDSYA 312
Query: 346 DGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIR 400
G ++ G+ SLD+ GL +FK E++GE++ P++ L H A +Y R
Sbjct: 313 LGATVYDLRGISDSLDESDHLFGLIQFKVGTGGQAAEYLGEWDFPLNKLLHKALDIYMSR 372
Query: 401 K 401
+
Sbjct: 373 R 373
>ref|YP_810465.1| Peptidoglycan interpeptide bridge formation enzyme [Oenococcus oeni
PSU-1]
gb|ABJ56800.1| Peptidoglycan interpeptide bridge formation enzyme [Oenococcus oeni
PSU-1]
Length = 388
Score = 82.4 bits (202), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 88/382 (23%), Positives = 169/382 (44%), Gaps = 49/382 (12%)
Query: 51 KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRD---LVAFTMKTLKDYGKTKKALF 107
KE+ +V +L+ K+ + I GP++D+ + + ++AF +K L Y K + A +
Sbjct: 19 KEKDEVLLTALMRKIKNHTGDVYEIMGGPLVDFENENNNQIIAFFLKELHKYLKKQHAYY 78
Query: 108 IKYDPA--------------ILLKQYALGQEEEEKPLALAA---IKNLQEAGVHWTGLTM 150
++ P LK Y+ L A ++ ++ G +
Sbjct: 79 LRIVPNEKTQRVENNGKVVNYDLKNYS--------SLYFAEGFIYRSFEQVGYGFATPHY 130
Query: 151 EIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
E I+ ++ L + K T+ IK + G+ T +S EL F + + T
Sbjct: 131 EYQKRIEG------LNKKTLFQSYSKKTQYSIKKTYEFGITTRNISYDELEMFHENTTKT 184
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQ----------QLILINQ 260
KR + +Y+Q + T+GD A +A++N+ + +++ Q+ILI
Sbjct: 185 AKRLGFYDKELSYYQSVYRTFGDNAKFMIAEINLSDYIGHFQEIIRNLKDKIDQMILI-- 242
Query: 261 DITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYA 320
D R + + +++K+L Q E+ I + + +QY +++ +AG L + +++
Sbjct: 243 DSKREKPTKTRQIKELRSQVEQHEKRIVQAKKLIEQYGKKINLAGALFFIQPQEVSYMFS 302
Query: 321 GMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG--SLDDGLTKFKANFAPTIEEF 378
N +FK FY Y ++ + A ++ + N GV G S DG+ +FK F + +
Sbjct: 303 YTNAEFKNFYGPYRTQADMLEFALKEKVPVYNFYGVSGDRSGHDGVYEFKKGFQGYMVDN 362
Query: 379 IGEFNLPVSPL-YHIANTMYKI 399
+G F LP++ Y T+ KI
Sbjct: 363 MGAFILPINKFRYQFLQTIKKI 384
>ref|YP_810968.1| Peptidoglycan interpeptide bridge formation enzyme [Oenococcus oeni
PSU-1]
gb|ABJ57303.1| Peptidoglycan interpeptide bridge formation enzyme [Oenococcus oeni
PSU-1]
Length = 422
Score = 82.4 bits (202), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 90/403 (22%), Positives = 173/403 (42%), Gaps = 42/403 (10%)
Query: 16 EHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLI-KLLPLGRSI 72
E+ +F H Q + +Q ++ + K +G+ + +V + +L+ + LG ++
Sbjct: 12 EYANFENNHPQGNFVQSAEQKSLLEKRGENAALVGLKDDTGKVVAGALVTWAKVKLG-NL 70
Query: 73 IYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA-----LGQEEE- 126
I RGP++DY + L+ + L + K + LFI+ P I +Y +G +
Sbjct: 71 FSIERGPLLDYSNEQLIKAFISGLTVFSKKRDGLFIRIRPNIAYAKYTERGKLIGDKNTT 130
Query: 127 --EKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ----ANIYTQENLEMQFPKHTRR 180
EK +LAA L + G + S +P +Q E++ + + +
Sbjct: 131 FVEKLNSLAADHQLPQIG---------FSTSSEPEWQFVKDLTEVDPEHVVKSYNRQAKY 181
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
+ KQ +K ++ + EL F +I T R + ++ +++ L TYG KA A
Sbjct: 182 HLNKNKQFCIKLRKIGRDELPAFKRITQQTADRLHYHDKSLDFYETLFDTYGKKAKFIFA 241
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITE---FEGFTDQY 297
++N + + + L I + +T + L D AS +R+++E E +
Sbjct: 242 EINFKEYSESIEKDLNDIQKKLTEIAGADYHNISDLSDFSASAKRHLSEGIKTETALQKR 301
Query: 298 PEE------------VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
+E V+V+ L + + LY+G ++ ++ + Y + + +A +
Sbjct: 302 LQEAKKMHQEAKHDIVLVSVALFVIENQEVVYLYSGSDEKYEHLFAPYEIQDTMITEAVK 361
Query: 346 DGIIWANMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPV 386
+ I N GV G D DG+ FK +F E +G F+ PV
Sbjct: 362 ERIPLYNFYGVSGKFDGSDGVLGFKTHFNGYTREMVGSFDFPV 404
>ref|ZP_02076510.1| hypothetical protein EUBDOL_00299 [Eubacterium dolichum DSM 3991]
gb|EDP12053.1| hypothetical protein EUBDOL_00299 [Eubacterium dolichum DSM 3991]
Length = 422
Score = 81.6 bits (200), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 78/402 (19%), Positives = 173/402 (43%), Gaps = 25/402 (6%)
Query: 10 IGISEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLP 67
+ +++EE+ SF + Q + AK++ W+ +G+ + + + + +L +
Sbjct: 4 VVLTKEEYSSFFNSSHLQNFWQSVEMAKMRESRGWEIHYVGVKENDILLCAATLQSLQVY 63
Query: 68 LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYAL---GQE 124
G + RG ++DY + +L+ F ++ +K Y K L++K DP I + + +
Sbjct: 64 RGYKLFMALRGFLVDYHNEELLRFFIQNVKAYVNDNKCLYMKIDPYISYQPHDIDGNAMP 123
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKH----TRR 180
+K L A+ +E G G D +PR+ + + T E + K+ T+R
Sbjct: 124 NGKKEDGLIAL--FEEYGFVHQGFRTYHDDEFEPRWISVLNTANTTEEEILKNMHSMTKR 181
Query: 181 LIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
I K+ ++ + + +L ++ T RKN +N AY+ + + + A
Sbjct: 182 NIAFTKKNNIEVCTLERDQLSILDDVIRETGGRKNFHSQNLAYYTSMYDCFKEHFEAKAA 241
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQ---------AHQKKRLKKLEDQKASLERYITEFE 291
+ P + + +++ ++ I + + + +LK L+ Q+ L++ + E
Sbjct: 242 YIYFPTYITKTEGEVLNLSAQIDKLEIACAQNPDAKKKTNQLKDLKRQQEVLKKRLCEAA 301
Query: 292 GFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWA 351
++ + + +A + + Y + + L+ G + F +F Y + ++ ++ I
Sbjct: 302 ELQREHGDTLYLAAAMFLKYDSEILYLFGGSYEKFHQFKGSYAIQWDMIKECINRKIPRY 361
Query: 352 NMGGVEGSL-----DDGLTKFKANFAPTIEEFIGEFNLPVSP 388
N G+ G+ D G+ FK F + E +G+F P
Sbjct: 362 NFYGISGNFHEDAEDYGVYLFKKGFHADVVELLGDFIYIADP 403
>ref|NP_695486.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium longum
NCC2705]
gb|AAN24122.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium longum
NCC2705]
Length = 426
Score = 81.3 bits (199), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 88/416 (21%), Positives = 177/416 (42%), Gaps = 31/416 (7%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSD---WAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPL 68
I+ EE D + Q S Q S AKI+ + E +G+ + + +++ L
Sbjct: 17 ITPEEFDRLSEATSQGSFQQWSGQVRLAKIRGH-EAECVGVCDASGNLVAGCVILYLNGR 75
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYAL-GQEEEE 127
+ + GP+ D L+ + +++ + A+ + P + + Y+ GQ + E
Sbjct: 76 FGADGSVYFGPIGISDDPALLRAITEAIRESARRHHAVSVACWPNVAYRLYSSDGQPDGE 135
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHTRRLI 182
AL + +AG WT + ++ I + L F K + +
Sbjct: 136 PNDAL--LTGFTDAG--WTHGGFHTGYDVVCQWMYVKDLTGITNGKELLASFGKRAQWSV 191
Query: 183 KDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKV 242
K A+ GV + E F+ I T +R+ + R YF++ YG A+ LA++
Sbjct: 192 KRAQSMGVHVREIGPDEFDVFADIERRTGERRGFATRGADYFRQFKQAYGADAHFMLAEI 251
Query: 243 NIPQKLDQYRQQLILINQDITRTQAHQKKR-LKKLEDQ-------KASLERYITEFEGFT 294
+I + + + + + + Q +R ++E Q A+ ++ + E EG+
Sbjct: 252 HIAEYVADMTAKREALQTKVAQLQTKYDERPTTRIERQLGEESRNLAAADKRLAEVEGYA 311
Query: 295 DQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLL-YPNVFQDAYQDGIIWANM 353
+ + + A + +S+ N + Y+G +++K FY L+ Y + + G+ N
Sbjct: 312 KK-GDVLPAAASMFVSHPNEVVYQYSGSLEEYKPFYASALIQYEAMLHLCVEQGVSRYNF 370
Query: 354 GGVEGSLDD------GLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMYKIRKQ 402
G+ G DD G+ +FK F +E+ +G+F LPV + ++N +K+ ++
Sbjct: 371 YGISGVFDDPNNEGRGVLEFKQGFNGYVEQMVGKFTLPVDKFRFGVSNLAHKLLRR 426
>ref|NP_624914.1| hypothetical protein SCO0602 [Streptomyces coelicolor A3(2)]
emb|CAB61296.1| conserved hypothetical protein SCF55.26 [Streptomyces coelicolor
A3(2)]
Length = 373
Score = 81.3 bits (199), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 99/421 (23%), Positives = 166/421 (39%), Gaps = 86/421 (20%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV--ASLSLLIKLLPLG 69
I+ EEH FV +S LQ W +K W+ E +G + E ++ A L LL L L
Sbjct: 8 ITREEHLRFVAARPSVSHLQVPSWGDVKPDWRAESLGWFDEGGELVGAGLVLLRPLPRLK 67
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA--------- 120
R + Y+P GPV+D+ D + ++ + + + + A ++ P ++ ++++
Sbjct: 68 RYLAYLPEGPVIDW-SADGLERWLEPMLAHLRGRGAFTVRMGPPVVARRWSAEAVKAAIA 126
Query: 121 ------LGQEE--EEKPLALAAIKNLQEAGVHWTGLTMEIADSI---QPRFQANI----Y 165
LG E E +P A A + L+ G W AD QPR +
Sbjct: 127 DPGARRLGDVEATEHEPGADALAERLRRMG--WRRTEPGGADGFAAGQPRHVCQVPLAGR 184
Query: 166 TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQ 225
+ E L+ F + RR IK A + GVK R Q +L F ++ T +R + R AYFQ
Sbjct: 185 SLEQLQNGFNQQWRRNIKKADKAGVKVVRGDQEDLPVFYELYVETARRDRFAPRPLAYFQ 244
Query: 226 KLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLER 285
++ Q L + D R
Sbjct: 245 RMW------------------------QALTAEDPDRMRL-------------------- 260
Query: 286 YITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQ 345
Y+ +G EV+ A + ++ G + Y ++ P L + DA +
Sbjct: 261 YLAHHDG-------EVLAAATM-LTVGEHVWYSYGASTGRRREVQPNNALQWRMMCDARE 312
Query: 346 DGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIR 400
G + G+ +LD+ GL +FK E++GE+ P++ + H A +Y R
Sbjct: 313 LGAAVYDFRGITDTLDEDNHLLGLLRFKVGAGGKAVEYLGEWEYPLNRVLHKAVALYLAR 372
Query: 401 K 401
+
Sbjct: 373 R 373
>gb|AAC69635.1| factor essential for methicillin resistance FEMA [Staphylococcus
sciuri]
Length = 417
Score = 80.9 bits (198), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 89/382 (23%), Positives = 173/382 (45%), Gaps = 33/382 (8%)
Query: 47 IGIYKEEKQVASLSLLIKLLPLGR-SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKA 105
+G+ + +V + LL + + + + Y RGPVMDY +++LV F K + Y K+ K
Sbjct: 43 VGVKDNQGEVLAACLLTSVPVMKKFNYFYSNRGPVMDYDNKELVDFFFKEIVSYLKSYKG 102
Query: 106 LFIKYDPAILLKQYALGQEEEEKPLAL---AAIKNLQEAGVHWTGLTMEIADSIQPRFQA 162
LF + DP + Y L + + IK + G G T Q R+ +
Sbjct: 103 LFFRIDPYL---PYQLRDHDGNIKKSFNRDGLIKQFESLGYEHQGFTTGFHPIHQIRWHS 159
Query: 163 NIYTQENLEMQFPKHT----RRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISL 218
+ + E K+ +R K ++ GVK +S+ E+ F + + T ++K+ +
Sbjct: 160 VLDLESMDEKTLIKNMDSLRKRNTKKVQKNGVKVRFLSKDEMPIFRQFMEDTTEKKDFND 219
Query: 219 RNEAYFQKLMTTYGDKAYLHLAKVN----IPQ---KLDQYRQQLILINQDITRTQAHQK- 270
R + ++ + Y + + LA ++ IPQ + +QY + + +D+ + +QK
Sbjct: 220 RGDDFYYNRL-KYFENVKIPLAYIDFETYIPQLEKEHEQYNKDIAKAEKDLEKKPDNQKT 278
Query: 271 -KRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEMLY--AGMNDDF 326
++ L+ Q+ + E + E ++ + + + AG I N E++Y G ++++
Sbjct: 279 INKIDNLKQQREANEAKLEEALQLQQEHGDTLPIAAGFFII---NPFEVVYYAGGSSNEY 335
Query: 327 KKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANFAPTIEEFIGE 381
+ F Y + + + A I N G+ G D G+ KFK + + E+IG+
Sbjct: 336 RHFAGSYAIQWEMIKYALDHNIDRYNFYGISGDFSEDAPDVGVIKFKKGYNADVYEYIGD 395
Query: 382 FNLPVS-PLYHIANTMYKIRKQ 402
F P++ P Y T+ K+ K+
Sbjct: 396 FVKPINKPAYKAYTTLKKVLKK 417
>ref|YP_001825188.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus
NBRC 13350]
dbj|BAG20505.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus
NBRC 13350]
Length = 372
Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 89/422 (21%), Positives = 172/422 (40%), Gaps = 89/422 (21%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV--ASLSLLIKLLPLG 69
IS E+H ++++ S Q WA +K +W++E +G + + ++ A L L +L +
Sbjct: 8 ISREQHLAYIQSLPSASHCQVPAWADVKTEWRSENLGWFDKNGEIVGAGLVLYRQLPKIK 67
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY--ALGQEEEE 127
R + Y+P GPV+++ +L + L K + A +K P ++++++ A + +
Sbjct: 68 RYLAYLPEGPVINWYAPNLEDWLQPMLAHL-KQQGAFSVKMGPPVVIRRWDSAAIKSGIQ 126
Query: 128 KPLALAAIKNLQEA-GVHWTGLTMEIAD------------------SIQPR--FQANIYT 166
P +K L++ H E++D +QPR FQ +
Sbjct: 127 DP----DVKRLRDVEATHIEPRAFEVSDRLRKMGWQQGEDGGAGFGDVQPRYVFQVPLAN 182
Query: 167 Q--ENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYF 224
+ E++ F + RR IK A + GV+ + +L ++ ++ +T R R +YF
Sbjct: 183 RSLEDVLKGFNQLWRRNIKKADKAGVEVVQGGYEDLAEWQRLYEITAVRDRFRPRPLSYF 242
Query: 225 QKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLE 284
Q++ T +L ++D R +
Sbjct: 243 QRMWT--------------------------VLNSEDPNR------------------MR 258
Query: 285 RYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAY 344
Y G +VV G + SYG ++ ++ P + + +D+Y
Sbjct: 259 LYFARHNGVNLSAATMLVVGGHVWYSYG--------ASDNIGREVRPSNAMQWRMLRDSY 310
Query: 345 QDGIIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKI 399
G ++ G+ SLD+ GL +FK E++GE++ P++ L H A +Y
Sbjct: 311 AMGATVYDLRGISDSLDETDHLFGLIQFKVGTGGEAVEYVGEWDFPLNKLLHKALDIYMS 370
Query: 400 RK 401
R+
Sbjct: 371 RR 372
>sp|Q2YXZ5|FEMA_STAAB Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
Length = 420
Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 89/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 33 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 92 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNASNDWFFDKMSNLGFEHTGFHKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 152 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 212 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 271
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 272 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 326
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 327 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDTGVVKFKKGY 386
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 387 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 419
>ref|YP_416706.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus RF122]
emb|CAI80918.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus RF122]
Length = 433
Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 89/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 46 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 104
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 105 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNASNDWFFDKMSNLGFEHTGFHKGFDP 164
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 165 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 224
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 225 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 284
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 285 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 339
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 340 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDTGVVKFKKGY 399
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 400 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 432
>ref|NP_825468.1| hypothetical protein SAV_4291 [Streptomyces avermitilis MA-4680]
dbj|BAC72003.1| hypothetical protein [Streptomyces avermitilis MA-4680]
Length = 373
Score = 80.1 bits (196), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 89/419 (21%), Positives = 165/419 (39%), Gaps = 82/419 (19%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKE---EKQVASLSLLIKLLPL 68
IS E+H ++++ S +Q WA +K +W++E +G + + E A L L +L +
Sbjct: 8 ISREQHLAYIQSLPAASHMQVPAWADVKAEWRSESLGWFDDRTGEMVGAGLVLYRQLPKI 67
Query: 69 GRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG------ 122
R + Y+P GPV+++ +L + L K + A +K P ++++++
Sbjct: 68 KRYLAYLPEGPVINWFAPNLDDWLQPMLAHL-KQQGAFSVKMGPPVIIRRWEAASIKGGI 126
Query: 123 QEEEEK-----------PLALAAIKNLQEAGVHWTGLTMEIADSIQPR--FQANIYTQ-- 167
Q + K P A L+ G +QPR FQ + +
Sbjct: 127 QNPDVKRLRDIEADFIEPRAFEVADKLRRMGWQQGEDGGAGFGDVQPRYVFQVPLANRSL 186
Query: 168 ENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKL 227
E + F + RR IK A++ GV+ + +L ++ ++ +T R + R +YFQ++
Sbjct: 187 EEVHKNFNQLWRRNIKKAEKAGVEVVQGGYHDLEEWQRLYEITAVRDHFRPRPLSYFQRM 246
Query: 228 MTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYI 287
T L +D R + Y
Sbjct: 247 WTA--------------------------LNTEDPNR------------------MRLYF 262
Query: 288 TEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDG 347
G +VV G + SYG ++ ++ P + + +D+Y G
Sbjct: 263 ARHNGVNLSAATMLVVGGHVWYSYG--------ASDNIGREVRPSNAMQWRMLRDSYALG 314
Query: 348 IIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRK 401
++ G+ SLD+ GL +FK E++GE++ P++ L H A +Y R+
Sbjct: 315 ATVYDLRGISDSLDETDHLFGLIQFKVGTGGEAAEYLGEWDFPLNKLLHKALDIYMSRR 373
>ref|NP_371898.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus Mu50]
ref|NP_374487.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus N315]
ref|YP_001246805.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
ref|YP_001316601.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
ref|YP_001441952.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus Mu3]
sp|Q7A5R3|FEMA_STAAN Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
sp|Q99UA7|FEMA_STAAM Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
dbj|BAB42466.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus N315]
dbj|BAB57536.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus Mu50]
gb|ABQ49229.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH9]
gb|ABR52314.1| Methicillin resistance protein [Staphylococcus aureus subsp. aureus
JH1]
dbj|BAF78245.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus Mu3]
Length = 420
Score = 79.7 bits (195), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 89/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 33 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 92 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 152 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 212 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 271
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 272 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 326
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 327 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 386
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 387 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 419
>ref|NP_646078.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus MW2]
ref|YP_043438.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus MSSA476]
ref|YP_499900.1| methicillin resistance factor, FemA, putative [Staphylococcus
aureus subsp. aureus NCTC 8325]
ref|YP_001332320.1| methicillin resistance protein FemA [Staphylococcus aureus subsp.
aureus str. Newman]
ref|YP_001575200.1| methicillin resistance factor FemA [Staphylococcus aureus subsp.
aureus USA300_TCH1516]
ref|ZP_02761174.1| methicillin resistance protein FemA [Staphylococcus aureus subsp.
aureus USA300_TCH1516]
sp|Q6G9I5|FEMA_STAAS Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
sp|Q5HG45|FEMA_STAAC Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
sp|P0A0A5|FEMA_STAAU Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
sp|P0A0A4|FEMA_STAAW Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
sp|Q2FYR2|FEMA_STAA8 Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
dbj|BAB95126.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus MW2]
emb|CAG43091.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus MSSA476]
gb|ABD30468.1| methicillin resistance factor, FemA, putative [Staphylococcus
aureus subsp. aureus NCTC 8325]
dbj|BAF67558.1| methicillin resistance protein FemA [Staphylococcus aureus subsp.
aureus str. Newman]
gb|ABX29321.1| methicillin resistance factor FemA [Staphylococcus aureus subsp.
aureus USA300_TCH1516]
Length = 420
Score = 79.7 bits (195), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 89/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 33 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 92 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 152 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 212 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 271
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 272 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 326
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 327 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 386
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 387 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 419
>pdb|1LRZ|A Chain A, X-Ray Crystal Structure Of Staphylococcus Aureus Fema
Length = 426
Score = 79.7 bits (195), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 89/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 33 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 92 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 152 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 212 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 271
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 272 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 326
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 327 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 386
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 387 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 419
>ref|YP_186262.1| femA protein [Staphylococcus aureus subsp. aureus COL]
ref|YP_493966.1| methicillin resistance protein FemA [Staphylococcus aureus subsp.
aureus USA300]
emb|CAA35679.1| FemA protein [Staphylococcus aureus]
gb|AAW38155.1| femA protein [Staphylococcus aureus subsp. aureus COL]
gb|ABD21750.1| methicillin resistance protein FemA [Staphylococcus aureus subsp.
aureus USA300_FPR3757]
Length = 433
Score = 79.7 bits (195), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 89/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 46 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 104
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 105 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 164
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 165 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDT 224
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 225 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 284
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 285 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 339
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 340 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 399
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 400 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 432
>ref|YP_001034837.1| hypothetical protein SSA_0861 [Streptococcus sanguinis SK36]
gb|ABN44287.1| Conserved hypothetical protein [Streptococcus sanguinis SK36]
Length = 411
Score = 79.0 bits (193), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 97/398 (24%), Positives = 171/398 (42%), Gaps = 26/398 (6%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
+S+EE Q S +Q + ++ K + + +G + QV ++L + G
Sbjct: 6 LSQEEFIQHTSASSQRSFMQTVEMTELLSKRGFNTQYVGYTDPQGQVVVSAVLYSMPMTG 65
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY-ALGQEEEEK 128
+ I GPV D + + L+ Y K + AL + P + + + GQ E+
Sbjct: 66 GLHMEINCGPVS--TDAQYLTPFYQALQAYAKKEGALELIIKPYETYQTFDSNGQPTSEE 123
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ-----ANIYTQENLEMQFPKHTRRLIK 183
L I+ L + G + GL +P + A++ T+++L F K+ + +K
Sbjct: 124 KGEL--IQQLTDLGFAFDGLQTGYPGG-EPDWHYVKDLADL-TEKDLLKSFSKNGKATVK 179
Query: 184 DAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
A G+K R+ + +L F I + T R+ + Y+Q ++G +A A +N
Sbjct: 180 KANTFGIKLKRLERDQLSIFKDITAATSDRREYDDKPLDYYQDFYDSFGQQADFMTASLN 239
Query: 244 IPQKLDQYRQQLILINQDITRTQAHQKK---------RLKKLEDQKASLERYITEFEGFT 294
L ++ + Q I + QA +K +L++L Q S E E +
Sbjct: 240 FKDYLQNLQKDQEKLGQKIQKLQADLEKNPQSEKKQNQLRELSSQFDSFETRKAEAQELI 299
Query: 295 DQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANM 353
D+Y ++ ++A L I L++G +F KFY LL V ++ + GI + N
Sbjct: 300 DKYGDQDQILAASLFIYTPQEATYLFSGSYPEFNKFYAPALLQEYVMTESIKRGIPFYNF 359
Query: 354 GGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
G+ G D DG+ +FK NF I +G F +PL
Sbjct: 360 LGIMGIFDGSDGVLRFKQNFNGFIVRKMGTFRYYPNPL 397
>gb|AAD33940.1|AF144661_1 factor essential for methicillin resistance [Staphylococcus aureus
subsp. anaerobius]
Length = 420
Score = 79.0 bits (193), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 94/395 (23%), Positives = 174/395 (44%), Gaps = 36/395 (9%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 33 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAA--IKNLQEAGVHWTGLTMEI 152
L Y K + L++ DP L QY L + E A + G TG
Sbjct: 92 ELSKYVKKHRCLYLHIDP-YLPYQY-LNHDGEITGNAGNGWFFDKMSNLGFEHTGFHKGF 149
Query: 153 ADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVS 208
+Q R+ + + T +++ +R K K+ GVK +S+ EL F +
Sbjct: 150 DPVLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFME 209
Query: 209 LTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT--- 265
T + K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 DTSESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKD 269
Query: 266 --------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVME 316
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E
Sbjct: 270 IEKRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFE 324
Query: 317 MLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKA 369
++Y G ++ F+ F Y + + A GI N GV G D G+ KFK
Sbjct: 325 VVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKK 384
Query: 370 NFAPTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
+ I E++G+F P + P+Y + K++ ++
Sbjct: 385 GYNAEIIEYVGDFIKPSNKPVYTAYTALKKVKDRI 419
>gb|AAC46073.1| zoocin A immunity factor [Streptococcus equi subsp. zooepidemicus]
Length = 410
Score = 78.2 bits (191), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 61/222 (27%), Positives = 106/222 (47%), Gaps = 12/222 (5%)
Query: 166 TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQ 225
T ENL F K R L+K + G+K ++++ EL F+ I + T R+ + + Y++
Sbjct: 161 TSENLLNSFSKKGRPLVKKSNTFGIKVRKLNKDELQIFANITNDTATRRGYNDKGLEYYE 220
Query: 226 KLMTTYGDKAYLHLAKVNIPQKLD-------QYRQQLILINQDITRTQAHQ--KKRLKKL 276
K + DK+ +A +N + L + ++ ++ + + + K +L++L
Sbjct: 221 KFFDAFKDKSEFTIATLNFREYLGNILDGRHRLENKISILGTRLDKNPNSEKIKNQLREL 280
Query: 277 EDQKASLERYITEFEGFTDQY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLL 335
Q+ + E + F +Y E+VV+AG L + + LY+G +F KFY LL
Sbjct: 281 NSQRETFLIREEEAKSFVKKYGDEDVVLAGSLFVYTQQELVYLYSGSYVEFNKFYAPALL 340
Query: 336 YPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANFAPTI 375
+A + GI + NM G+ G D DG+ FK NF I
Sbjct: 341 QEYAMLNALKKGIKFYNMLGITGKFDNSDGVLCFKQNFKGYI 382
>ref|YP_301461.1| factor essential for methicillin resistance FEMA [Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305]
emb|CAA73373.1| femA [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305]
dbj|BAE18516.1| factor essential for methicillin resistance FEMA [Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305]
Length = 420
Score = 78.2 bits (191), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 90/400 (22%), Positives = 179/400 (44%), Gaps = 34/400 (8%)
Query: 24 HQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVM 81
+ + + G+ KI + +GI + +V + LL + P+ + Y RGPV+
Sbjct: 20 NSHFTQMVGNYELKIAESTETHLVGIKNNDNEVIAACLLTAV-PVMKFFKYFYSNRGPVI 78
Query: 82 DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAA----IKN 137
D+ +++LV + L Y K AL+++ DP L QY + + + LA A
Sbjct: 79 DFENKELVHYFFNELAKYVKKHNALYLRVDP-YLAYQY---RNHDGEVLANAGHDWIFDK 134
Query: 138 LQEAGVHWTGLTMEIADSIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTY 193
+++ G G +Q RF + + T +++ +R K ++ GVK
Sbjct: 135 MKQLGYKHEGFLTGFDPILQIRFHSVLDLAGKTAKDVLNGMDSLRKRNTKKVQKNGVKVR 194
Query: 194 RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQ 253
+ + EL F + T + K+ R++ ++ + Y D+ + LA ++ + + + +
Sbjct: 195 FLGEDELPIFRSFMEDTSETKDFDDRDDDFYYNRLRYYKDRVLVPLAYMDFDEYITELKA 254
Query: 254 QLILINQDITRTQAHQKKRL--KKLEDQKASLERY-------ITEFEGFTDQYPEEVVVA 304
+ ++++DI + +KR KK ++K +LE+ I E +++ E+ ++
Sbjct: 255 EREVLSKDINKAVKDIEKRPENKKAYNKKENLEQQLIANQQKIDEATALQEKHGNELPIS 314
Query: 305 GILSISYGNVMEMLY--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-- 360
I N E++Y G +++F+ F Y + + A I N G+ G
Sbjct: 315 AAYFII--NPYEVVYYAGGTSNEFRHFAGSYAIQWKMINYAIDHNIDRYNFYGISGHFTE 372
Query: 361 ---DDGLTKFKANFAPTIEEFIGEFNLPVS-PLYHIANTM 396
D G+ KFK F + E++G+F P++ P+Y I T+
Sbjct: 373 DAEDAGVVKFKKGFNADVVEYVGDFIKPINKPMYKIYTTL 412
>ref|YP_040791.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus MRSA252]
sp|Q6GH31|FEMA_STAAR Aminoacyltransferase femA (Factor essential for expression of
methicillin resistance A)
emb|CAG40385.1| factor essential for expression of methicillin resistance
[Staphylococcus aureus subsp. aureus MRSA252]
Length = 420
Score = 78.2 bits (191), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 88/393 (22%), Positives = 171/393 (43%), Gaps = 32/393 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 33 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 91
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 92 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 151
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 152 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 211
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y ++ + LA +N + + + ++ ++N+D+ +
Sbjct: 212 SESKAFADRDDKFYYNRLKYYKERVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 271
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 272 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 326
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 327 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 386
Query: 372 APTIEEFIGEFNLPVS-PLYHIANTMYKIRKQL 403
I E++G+F P++ P+Y + K++ ++
Sbjct: 387 NAEIIEYVGDFIKPINKPVYAAYTALKKVKDRI 419
>gb|ABC75742.1| FemA [Staphylococcus aureus]
gb|ABC75745.1| FemA [Staphylococcus aureus]
gb|ABC75746.1| FemA [Staphylococcus aureus]
gb|ABC75749.1| FemA [Staphylococcus aureus]
gb|ABC75750.1| FemA [Staphylococcus aureus]
gb|ABC75751.1| FemA [Staphylococcus aureus]
Length = 405
Score = 78.2 bits (191), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 88/380 (23%), Positives = 165/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 31 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>gb|ABC75743.1| FemA [Staphylococcus aureus]
gb|ABC75744.1| FemA [Staphylococcus aureus]
Length = 405
Score = 77.8 bits (190), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 88/380 (23%), Positives = 165/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 31 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>gb|ABC75752.1| FemA [Staphylococcus aureus]
Length = 405
Score = 77.8 bits (190), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 88/380 (23%), Positives = 165/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 31 KLAEGFETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>gb|ABC75753.1| FemA [Staphylococcus aureus]
Length = 405
Score = 77.0 bits (188), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 88/380 (23%), Positives = 165/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 31 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKDRLLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>gb|ABC75741.1| FemA [Staphylococcus aureus]
Length = 405
Score = 76.3 bits (186), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 87/380 (22%), Positives = 165/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 31 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y ++ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKERVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>ref|ZP_02760942.1| femX protein [Staphylococcus aureus subsp. aureus USA300_TCH1516]
Length = 333
Score = 75.5 bits (184), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 77/323 (23%), Positives = 144/323 (44%), Gaps = 36/323 (11%)
Query: 93 MKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEI 152
+ + K+ K +KA IK DP + + + A++NL+ G G +
Sbjct: 2 LDSAKEIAKAEKAYAIKIDPDVEVDK------------GTDALQNLKALGFKHKGFKEGL 49
Query: 153 A-DSIQPRFQANIYTQEN---LEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVS 208
+ D IQPR +N L F + R ++ A +RG R + L F++++
Sbjct: 50 SKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMK 109
Query: 209 LTEKRKNISLRNEAYFQKLMTTY---GDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT 265
+T +R R+ +YF+ + GD A L L K++ + + + Q+L ++ +I +
Sbjct: 110 ITGERDGFLTRDISYFENIYDALHEDGD-AELFLVKLDPKENIAKVNQELNELHAEIAKW 168
Query: 266 QAHQK---KRLKKLED-------QKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVM 315
Q K K+ KK ++ + A E + E ++PE + ++G L + G+
Sbjct: 169 QQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKS 228
Query: 316 EMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLDD-----GLTKFKAN 370
LY +++F+ F P + + + + A + G + GG + D GL FK
Sbjct: 229 YYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKV 288
Query: 371 FAPTIEEFIGEFNLPVS-PLYHI 392
+ + E IGEF+ ++ PLY +
Sbjct: 289 WGTYLSEKIGEFDYVLNQPLYQL 311
>pdb|1XF8|A Chain A, Crystal Structure Of Weissella Viridescens Femx (Y254f)
Mutant
Length = 335
Score = 75.5 bits (184), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 94/392 (23%), Positives = 159/392 (40%), Gaps = 95/392 (24%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ---VASLSLLIKLLPLGRS 71
E ++ F+++ V Q WAK+KN W E + +Y E+ Q +A++S+L+ P +
Sbjct: 12 ERYEEFMRQSPYGQVTQDLGWAKVKNNW--EPVDVYLEDDQGAIIAAMSMLLGDTPTDKK 69
Query: 72 IIYIPRGPVMDYLDRD----LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEE 127
Y +GPVMD D D LV +K L +A +++DP + ++
Sbjct: 70 FAYASKGPVMDVTDVDLLDRLVDEAVKALD-----GRAYVLRFDPEVAYSDEFNTTLQDH 124
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI------YTQENLEMQFPKHTRRL 181
+ +N+ +AG+H T IQPR + + L++ +P T+
Sbjct: 125 G--YVTRNRNVADAGMHAT---------IQPRLNMVLDLTKFPDAKTTLDL-YPSKTKSK 172
Query: 182 IKDAKQRGVKTYRV-SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
IK + GV+ + S +EL +F K + +R I+ R YFQ++ +
Sbjct: 173 IKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAF--------- 223
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ D R ++ E EG +
Sbjct: 224 ------------------DADTMRI--------------------FVAEREG-------K 238
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-S 359
++ GI ++ YG + +YAG D +Y Y + + Q A ++GG+E S
Sbjct: 239 LLSTGI-ALKYGRKIWFMYAGSMDG-NTYYAPYAVQSEMIQWALDTNTDLYDLGGIESES 296
Query: 360 LDDGLTKFKANF---APTIEEFIGEFNLPVSP 388
DD L FK F AP E+IGE + + P
Sbjct: 297 TDDSLYVFKHVFVKDAP--REYIGEIDKVLDP 326
>ref|ZP_02920977.1| hypothetical protein STRINF_01861 [Streptococcus infantarius subsp.
infantarius ATCC BAA-102]
gb|EDT46856.1| hypothetical protein STRINF_01861 [Streptococcus infantarius subsp.
infantarius ATCC BAA-102]
Length = 392
Score = 75.1 bits (183), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 99/411 (24%), Positives = 174/411 (42%), Gaps = 52/411 (12%)
Query: 5 TFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIK 64
TFY + H SF++ + +L+ K +Q +G+ K+E+ + ++L
Sbjct: 14 TFYNTV-----SHKSFMQSVEMADLLK-------KRGYQVTYLGL-KDEETLQVAAVLFS 60
Query: 65 LLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQE 124
L G + I GP+ Y + L+ LKDY K A+ + P + +
Sbjct: 61 LPMTGGLHMEINSGPL--YQEETLLEPFYVALKDYAKKNGAIELVIKPYDNYQTFDSDGN 118
Query: 125 --EEEKPLALAAIKNL--QEAGVH---------WTGLTMEIADSIQPRFQANIYTQENLE 171
EE+ L +KNL Q G W L D + ++
Sbjct: 119 PISEEQSHFLDTLKNLGYQHDGFQTGYPEGEPVWHYLKTIKGDDTKSLLKS--------- 169
Query: 172 MQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTY 231
F K+ R I A G+ +++ E+ +F +I+ T KR+ ++ +Y+ L ++
Sbjct: 170 --FNKNCSRNITTALNYGISIRNITREEIPQFKQIIEETGKRQGFEDKSLSYYYDLYDSF 227
Query: 232 GDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFE 291
G A +A++N L Q++ L+N + + ++L+KLE QK ++ + E
Sbjct: 228 GPNAEFVVAEINSTAALAHLDQKISLLNPSAKQYE----QQLQKLEKQKNIVQGTLAGKE 283
Query: 292 GFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWA 351
E V +A L I + + L+ G ++KF +LL + + + Q GI
Sbjct: 284 S------ENVPLACALIIYTPSEVTYLFGGSYTKYQKFSAAFLLQYHAMKRSLQKGITLY 337
Query: 352 NMGGVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL-YHIANTMYKI 399
N G++G D DG+ +FK NF I +G F PL Y + + + KI
Sbjct: 338 NFLGIQGIFDGSDGVLRFKQNFNGYIVRKMGTFRYYPHPLKYKLIHNLKKI 388
>pdb|1NE9|A Chain A, Crystal Structure Of Weissella Viridescens Femx At 1.7 Ang
Resolution
pdb|1P4N|A Chain A, Crystal Structure Of Weissella Viridescens
Femx:udp-Murnac- Pentapeptide Complex
pdb|1XIX|A Chain A, Crystal Structure Of Weissella Viridescens Femx Form Ii
Length = 335
Score = 74.7 bits (182), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 94/392 (23%), Positives = 159/392 (40%), Gaps = 95/392 (24%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ---VASLSLLIKLLPLGRS 71
E ++ F+++ V Q WAK+KN W E + +Y E+ Q +A++S+L+ P +
Sbjct: 12 ERYEEFMRQSPYGQVTQDLGWAKVKNNW--EPVDVYLEDDQGAIIAAMSMLLGDTPTDKK 69
Query: 72 IIYIPRGPVMDYLDRD----LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEE 127
Y +GPVMD D D LV +K L +A +++DP + ++
Sbjct: 70 FAYASKGPVMDVTDVDLLDRLVDEAVKALD-----GRAYVLRFDPEVAYSDEFNTTLQDH 124
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI------YTQENLEMQFPKHTRRL 181
+ +N+ +AG+H T IQPR + + L++ +P T+
Sbjct: 125 G--YVTRNRNVADAGMHAT---------IQPRLNMVLDLTKFPDAKTTLDL-YPSKTKSK 172
Query: 182 IKDAKQRGVKTYRV-SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
IK + GV+ + S +EL +F K + +R I+ R YFQ++ +
Sbjct: 173 IKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAF--------- 223
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ D R ++ E EG +
Sbjct: 224 ------------------DADTMRI--------------------FVAEREG-------K 238
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-S 359
++ GI ++ YG + +YAG D +Y Y + + Q A ++GG+E S
Sbjct: 239 LLSTGI-ALKYGRKIWYMYAGSMDG-NTYYAPYAVQSEMIQWALDTNTDLYDLGGIESES 296
Query: 360 LDDGLTKFKANF---APTIEEFIGEFNLPVSP 388
DD L FK F AP E+IGE + + P
Sbjct: 297 TDDSLYVFKHVFVKDAP--REYIGEIDKVLDP 326
>gb|AAG21689.1| FemX [Weissella viridescens]
Length = 336
Score = 74.7 bits (182), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 94/392 (23%), Positives = 159/392 (40%), Gaps = 95/392 (24%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ---VASLSLLIKLLPLGRS 71
E ++ F+++ V Q WAK+KN W E + +Y E+ Q +A++S+L+ P +
Sbjct: 13 ERYEEFMRQSPYGQVTQDLGWAKVKNNW--EPVDVYLEDDQGAIIAAMSMLLGDTPTDKK 70
Query: 72 IIYIPRGPVMDYLDRD----LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEE 127
Y +GPVMD D D LV +K L +A +++DP + ++
Sbjct: 71 FAYASKGPVMDVTDVDLLDRLVDEAVKALD-----GRAYVLRFDPEVAYSDEFNTTLQDH 125
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI------YTQENLEMQFPKHTRRL 181
+ +N+ +AG+H T IQPR + + L++ +P T+
Sbjct: 126 G--YVTRNRNVADAGMHAT---------IQPRLNMVLDLTKFPDAKTTLDL-YPSKTKSK 173
Query: 182 IKDAKQRGVKTYRV-SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
IK + GV+ + S +EL +F K + +R I+ R YFQ++ +
Sbjct: 174 IKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAF--------- 224
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ D R ++ E EG +
Sbjct: 225 ------------------DADTMRI--------------------FVAEREG-------K 239
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-S 359
++ GI ++ YG + +YAG D +Y Y + + Q A ++GG+E S
Sbjct: 240 LLSTGI-ALKYGRKIWYMYAGSMDG-NTYYAPYAVQSEMIQWALDTNTDLYDLGGIESES 297
Query: 360 LDDGLTKFKANF---APTIEEFIGEFNLPVSP 388
DD L FK F AP E+IGE + + P
Sbjct: 298 TDDSLYVFKHVFVKDAP--REYIGEIDKVLDP 327
>ref|ZP_02963226.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium animalis
subsp. lactis HN019]
gb|EDT89384.1| FemAB-like protein possibly involved in interpeptide bridge
formation in peptidoglycan [Bifidobacterium animalis
subsp. lactis HN019]
Length = 427
Score = 74.7 bits (182), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 86/415 (20%), Positives = 176/415 (42%), Gaps = 33/415 (7%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
++E+E +F + Q + Q + A ++ + + +G+ ++ + A P+
Sbjct: 9 LNEQEFRAFAEASPQSNFQQTVEMANLRRMHGMDVDFVGMREDGEIKAGAVFATHHAPMA 68
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLK-----QYALGQE 124
+ + GP+ DY D +LVA ++ L + K K A+ + P + AL +
Sbjct: 69 -TFCSVISGPLCDYDDDELVAEFLRALARFAKKKGAVHLDIAPNQRYRVRDDHGEALPES 127
Query: 125 EEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQAN---IYTQENLEMQFPKHTRRL 181
E P I+N+++AG G +++ RF + I + L + K T+
Sbjct: 128 EGGAP-DKRMIRNIEQAGYEHGGFVRGYTSTVRWRFAKDMTGIGDESELLKSYSKRTQWS 186
Query: 182 IKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
IK A+ GV + EL F++I T +R++ R YF++ +G++A LA+
Sbjct: 187 IKRARSMGVHVREIGVDELDTFARIEQQTAERRHFEFRGPQYFKQFAQCFGERARFVLAE 246
Query: 242 VNIPQ-------KLDQYRQQLILINQDIT-RTQAHQKKRLKKLEDQKASLERYITEFEGF 293
++ + K D R + + I R ++RL + A+ + + E
Sbjct: 247 IDTAEYQRSMQRKADDLRALVDGLEAKIAQRETTKLRRRLNEESSNLAAANKRLAEANEL 306
Query: 294 TDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLL-YPNVFQDAYQDGIIWAN 352
++ A + + V+ L++G +++K FY L+ + + + Q + +
Sbjct: 307 VEKGDLIPAAASMFVLGPREVV-YLFSGSVEEYKPFYASALIQHEAMLRYCVQGVEPFGH 365
Query: 353 MG-----GVEGSLDD------GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTM 396
+ G++G DD G+ +FK F + E G+F + P+ + A +
Sbjct: 366 VNLYDFYGIDGIFDDPDDEGRGVLEFKQGFNGYVVEMPGDFMKVLRPVTYRAQRL 420
>gb|ABC75747.1| FemA [Staphylococcus aureus]
Length = 405
Score = 74.7 bits (182), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 87/380 (22%), Positives = 164/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+D +++LV F
Sbjct: 31 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDNENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y D+ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + E+ I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>ref|YP_755077.1| methicillin resistance protein [Syntrophomonas wolfei subsp. wolfei
str. Goettingen]
gb|ABI69706.1| methicillin resistance protein [Syntrophomonas wolfei subsp. wolfei
str. Goettingen]
Length = 366
Score = 74.3 bits (181), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 92/396 (23%), Positives = 161/396 (40%), Gaps = 90/396 (22%)
Query: 14 EEEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLLPLG-- 69
++ + FV H + LQ +W ++K W+ + + ++ + ASL +L + LPL
Sbjct: 12 KDRYKRFVDSHPKGHFLQLWEWGQVKKGTGWEPLPLVLEQDGEIRASLLILKRKLPLPGL 71
Query: 70 -RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEK 128
+ I Y PRGPV D + + + + + A+F+K DP + + + ++
Sbjct: 72 KKCIFYSPRGPVADLENEEQITALFNGAARVARDEGAIFLKIDPDV-----SCHNQHFQE 126
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRF-------QANIYTQENLEMQFPKHTRRL 181
L A K + TGL E +QP F + I EN+ ++ R
Sbjct: 127 ILQRAGFKKNE------TGLNFE---GVQPNFVFRLDITPSEIKLLENMHSKW----RYN 173
Query: 182 IKDAKQRGVKTYRV-SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
I+ A ++GVK + S+ ++ F +++ T +R +R YF+ + +K LA
Sbjct: 174 IRLAGRKGVKVRKAESKEDMRLFYELLQETAQRDKFLIRGYEYFEWIWEYMVEK---KLA 230
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
V ++ E++G
Sbjct: 231 CV-------------------------------------------FLAEYQG-------R 240
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL 360
+V A + IS G V LY ++ + P YL+ + Q A Q G + GV G L
Sbjct: 241 LVAATLALISAGKVW-YLYGASSNLHRNIMPNYLIQWEMIQWARQQGCSIYDFRGVSGDL 299
Query: 361 DD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYH 391
D+ GL +FK F + EF+GE++ SPL++
Sbjct: 300 DEDNPLYGLYRFKKGFNGDLVEFVGEWDKVYSPLFY 335
>gb|ABC75748.1| FemA [Staphylococcus aureus]
Length = 405
Score = 73.9 bits (180), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 86/380 (22%), Positives = 164/380 (43%), Gaps = 32/380 (8%)
Query: 37 KIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI--IYIPRGPVMDYLDRDLVAFTMK 94
K+ ++ +GI +V + LL +P+ + Y RGPV+DY +++LV F
Sbjct: 31 KLAEGYETHLVGIKNNNNEVIAACLLTA-VPVMKVFKYFYSNRGPVIDYENQELVHFFFN 89
Query: 95 TLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIAD 154
L Y K + L++ DP + + E + G TG
Sbjct: 90 ELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDP 149
Query: 155 SIQPRFQANI----YTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLT 210
+Q R+ + + T +++ +R K K+ GVK +S+ EL F + T
Sbjct: 150 VLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDT 209
Query: 211 EKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRT----- 265
+ K + R++ ++ + Y ++ + LA +N + + + ++ ++N+D+ +
Sbjct: 210 SESKAFADRDDKFYYNRLKYYKNRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIE 269
Query: 266 ------QAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV-VVAGILSISYGNVMEML 318
+AH K+ L+ Q + + I E + +++ E+ + AG I N E++
Sbjct: 270 KRPENKKAHNKR--DNLQQQLDANAQKIEEGKRLKEEHGNELPISAGFFFI---NPFEVV 324
Query: 319 Y--AGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL-----DDGLTKFKANF 371
Y G ++ F+ F Y + + A GI N GV G D G+ KFK +
Sbjct: 325 YYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGY 384
Query: 372 APTIEEFIGEFNLPVS-PLY 390
I E++G+F P++ P+Y
Sbjct: 385 NAEIIEYVGDFIKPINKPVY 404
>ref|YP_001450901.1| MurN protein [Streptococcus gordonii str. Challis substr. CH1]
gb|ABV10049.1| MurN protein [Streptococcus gordonii str. Challis substr. CH1]
Length = 411
Score = 73.2 bits (178), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 92/397 (23%), Positives = 169/397 (42%), Gaps = 24/397 (6%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
+S+EE Q S +Q + A++ K + + +G + QV ++L + G
Sbjct: 6 LSQEEFIQHTSASSQRSFMQTVEIAELLSKRGFSTQYVGYTDPQGQVVVSAILYSMSMTG 65
Query: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQY-ALGQEEEEK 128
+ I GPV + + + L+ Y K + AL + P + + + GQ ++
Sbjct: 66 GLHMEINCGPVS--TNAQYLTPFYQALQAYAKKEGALELIIKPYETYQTFDSNGQPTSDE 123
Query: 129 PLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ----ANIYTQENLEMQFPKHTRRLIKD 184
+ L I+ L + G + GL +P + T+++L F K+ + +K
Sbjct: 124 KVEL--IQQLTDLGFDFDGLQTGYPGG-EPDWHYVKDLTGLTEKDLLKSFSKNGKATVKK 180
Query: 185 AKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI 244
A G+K R+ + +L F I + T R+ + Y++ ++G +A A +N
Sbjct: 181 ANTFGIKLKRLERDQLSIFKDITAATSDRRKYDDKPLDYYKDFYDSFGQQADFMTASLNF 240
Query: 245 PQKLDQYRQQLILINQDITRTQAH---------QKKRLKKLEDQKASLERYITEFEGFTD 295
L ++ + Q I + +A ++ +L++L Q S E E + D
Sbjct: 241 KDYLQNLQKDQEKLGQKIQKLRADLENNPQSEKKQNQLRELSSQFDSFETRKAEAQDLID 300
Query: 296 QYPE-EVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMG 354
+Y + + V+A L I L++G +F KFY LL V ++ + I + N
Sbjct: 301 KYGDKDQVLAASLFIYTPQEATYLFSGSYPEFNKFYAPALLQEYVMTESIKRDIPFYNFL 360
Query: 355 GVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
G+ G D DG+ +FK NF I +G F +PL
Sbjct: 361 GIMGIFDGSDGVLRFKQNFNGFIVRKMGTFRYYPNPL 397
>pdb|1XE4|A Chain A, Crystal Structure Of Weissella Viridescens Femx (K36m)
Mutant
Length = 335
Score = 72.4 bits (176), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/392 (23%), Positives = 158/392 (40%), Gaps = 95/392 (24%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQ---VASLSLLIKLLPLGRS 71
E ++ F+++ V Q WAK+ N W E + +Y E+ Q +A++S+L+ P +
Sbjct: 12 ERYEEFMRQSPYGQVTQDLGWAKVMNNW--EPVDVYLEDDQGAIIAAMSMLLGDTPTDKK 69
Query: 72 IIYIPRGPVMDYLDRD----LVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEE 127
Y +GPVMD D D LV +K L +A +++DP + ++
Sbjct: 70 FAYASKGPVMDVTDVDLLDRLVDEAVKALD-----GRAYVLRFDPEVAYSDEFNTTLQDH 124
Query: 128 KPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI------YTQENLEMQFPKHTRRL 181
+ +N+ +AG+H T IQPR + + L++ +P T+
Sbjct: 125 G--YVTRNRNVADAGMHAT---------IQPRLNMVLDLTKFPDAKTTLDL-YPSKTKSK 172
Query: 182 IKDAKQRGVKTYRV-SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLA 240
IK + GV+ + S +EL +F K + +R I+ R YFQ++ +
Sbjct: 173 IKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAF--------- 223
Query: 241 KVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE 300
+ D R ++ E EG +
Sbjct: 224 ------------------DADTMRI--------------------FVAEREG-------K 238
Query: 301 VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEG-S 359
++ GI ++ YG + +YAG D +Y Y + + Q A ++GG+E S
Sbjct: 239 LLSTGI-ALKYGRKIWYMYAGSMDG-NTYYAPYAVQSEMIQWALDTNTDLYDLGGIESES 296
Query: 360 LDDGLTKFKANF---APTIEEFIGEFNLPVSP 388
DD L FK F AP E+IGE + + P
Sbjct: 297 TDDSLYVFKHVFVKDAP--REYIGEIDKVLDP 326
>ref|YP_057014.1| FemAB family protein [Propionibacterium acnes KPA171202]
gb|AAT84056.1| FemAB family protein [Propionibacterium acnes KPA171202]
Length = 363
Score = 67.8 bits (164), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 60/236 (25%), Positives = 107/236 (45%), Gaps = 31/236 (13%)
Query: 20 FVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLP-LGRSIIYIPRG 78
F+ S LQ WA++K++W+ ER+G Y ++ +L + LP L R + Y+P G
Sbjct: 4 FIAARGSASFLQTPAWARVKSEWRGERVGFYDGDELTGVGLILYRKLPKLPRYLAYLPEG 63
Query: 79 PVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNL 138
PV+D+ RD +A L + K ++A ++ PA++ + + G + + +A I +L
Sbjct: 64 PVLDW-SRDDIAEHFDALVTHVKKRQAFAVRIGPAVVHRIW--GTKTIKTAIADDNITSL 120
Query: 139 QEA--------GVH---------W-TGLTMEIADSIQPRFQANIY---------TQENLE 171
E G H W T T + QP+F + +++ L
Sbjct: 121 TEVEPDIVTPEGEHVVSVLKQGGWITDETGHGFAAGQPQFNFQLSLRHEDGTQKSEDELL 180
Query: 172 MQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKL 227
+ RR IK A + GV+ ++ +L +F K+ T +R + R YF+ +
Sbjct: 181 KGMNQLWRRNIKKAAKFGVEVKLGTRDDLARFHKVYLETAERDGFTGRPLEYFEHM 236
>ref|YP_001635938.1| Methicillin resistance protein [Chloroflexus aurantiacus J-10-fl]
ref|ZP_02985678.1| Methicillin resistance protein [Chloroflexus sp. Y-400-fl]
gb|ABY35549.1| Methicillin resistance protein [Chloroflexus aurantiacus J-10-fl]
gb|EDU26843.1| Methicillin resistance protein [Chloroflexus sp. Y-400-fl]
Length = 352
Score = 66.6 bits (161), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 55/236 (23%), Positives = 109/236 (46%), Gaps = 23/236 (9%)
Query: 13 SEEEHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPLGR 70
S + D+FV H Q +VLQ S W +K + W RI +Y ++ + + + ++ G
Sbjct: 11 SAAQWDAFVASHPQGNVLQASPWGALKARFGWHCRRIAVYDDDGTIRAGAQVLFRRYAGL 70
Query: 71 SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPL 130
+ Y PRGP++ D L + ++ G+ A+ I+ +P + +++ + P
Sbjct: 71 AFGYTPRGPLLSG-DPALDNHLIDGMRRLGRQMLAVAIRLEPNVR-------EDDAQAP- 121
Query: 131 ALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHT---RRLIKDAKQ 187
+LQ +T + +A+ IQPR + Q +E F ++ R I+ A++
Sbjct: 122 ------HLQ---TWFTRHRLVVAEPIQPRSTILVDLQPPVETIFTAYSKGHRADIRRAER 172
Query: 188 RGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVN 243
GV +++L F I+ T +R ++ + AY+ + + L +A++N
Sbjct: 173 IGVTVRTGGEADLSTFYDIMRATGERAAFAIHSAAYYTTAWQLHQPHSCLLVAELN 228
>ref|ZP_00786006.1| beta-lactam resistance factor [Streptococcus agalactiae COH1]
gb|EAO75262.1| beta-lactam resistance factor [Streptococcus agalactiae COH1]
Length = 361
Score = 65.9 bits (159), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 60/235 (25%), Positives = 105/235 (44%), Gaps = 13/235 (5%)
Query: 135 IKNLQEAGVHWTGLTMEIADS-IQPRFQANI--YTQENLEMQFPKHTRRLIKDAKQRGVK 191
I++ +G H GLT + + N+ T E L F K R L+K A G+K
Sbjct: 127 IEDFTSSGYHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKAMSFGIK 186
Query: 192 TYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQ----- 246
+ + ELH F +I + T R++ ++ Y+Q ++ KA +A +N +
Sbjct: 187 VRVLKRDELHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFREYDHNL 246
Query: 247 --KLDQYRQQLILINQDITRTQAHQKKRLKKLE--DQKASLERYITEFEGFTDQYP-EEV 301
K + +L L+++ K ++ E +Q AS E E + F +Y ++V
Sbjct: 247 QIKAEALENKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQKYDNQDV 306
Query: 302 VVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGV 356
V+AG L + ++G +F KFY +L V Q+A + G + N+ G+
Sbjct: 307 VLAGSLFVYSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLGI 361
>ref|ZP_01515703.1| Methicillin resistance protein [Chloroflexus aggregans DSM 9485]
gb|EAV10577.1| Methicillin resistance protein [Chloroflexus aggregans DSM 9485]
Length = 350
Score = 64.7 bits (156), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 59/242 (24%), Positives = 108/242 (44%), Gaps = 32/242 (13%)
Query: 10 IGISEE-EHDSFVKEHQQISVLQGSDWAKIKNQ--WQNERIGIYKE-EKQVASLSLLIKL 65
IGI ++ + D+FV H ++LQ S W ++K + W R+ ++ VA +L +
Sbjct: 5 IGIPDQVQWDAFVAAHPHGNLLQASPWGRLKERFGWHCHRLAVFDSMGTPVAGCQVLFRR 64
Query: 66 LPLGRSIIYIPRGPVM---DYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALG 122
G + Y+PRGP++ +D L+ + L+ G A+ I+ +P +LL
Sbjct: 65 A-YGLAFGYVPRGPLLAGDPAIDDQLI----RALRWLGWRMAAVLIRLEPNVLL------ 113
Query: 123 QEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQANI---YTQENLEMQFPKHTR 179
++P A + + IA++IQPR + T+E L K R
Sbjct: 114 ----DEPHATTLMDWVHRH-------RWPIAETIQPRSTILVDLQPTEEALFAACSKGHR 162
Query: 180 RLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHL 239
I+ A++ GV +++L F I+ T R + ++ + AY+ + A L +
Sbjct: 163 ADIRRAERLGVTVRVGDETDLTTFYTIMQATGSRASFAIHSPAYYTAAWRLHQPHARLLI 222
Query: 240 AK 241
A+
Sbjct: 223 AE 224
>ref|YP_925855.1| Methicillin resistance protein [Nocardioides sp. JS614]
gb|ABL84168.1| Methicillin resistance protein [Nocardioides sp. JS614]
Length = 383
Score = 64.3 bits (155), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 55/246 (22%), Positives = 115/246 (46%), Gaps = 28/246 (11%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLP-LGR 70
I E +H + ++ + S LQ W ++K +W+ E IG ++ ++ V + +L + LP + R
Sbjct: 18 IPESDHLALLRSRRSASFLQTPAWGRVKAEWRRESIGWFRGDELVGAALVLYRQLPKVKR 77
Query: 71 SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPL 130
+ Y+P GPV+D+ DL + ++ + + + ++ P ++ +++ ++ +
Sbjct: 78 YLAYLPEGPVIDWEADDLREW-LEPMAAHLGARGVFGVRMGPPVVTRRWDAATIKDG--I 134
Query: 131 ALAAIKNLQE--------AGVHWTGLTMEIA----------DSIQPR--FQANIY--TQE 168
A A++ L + +G T E+ + QP+ FQ + T+E
Sbjct: 135 ADDAVRRLGDLPPTERTHSGARVTSQLTELGWRPQAVEGGFAAGQPQYVFQVPLAGRTEE 194
Query: 169 NLEMQFPKHTRRLIKDAKQRGVK--TYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQK 226
++ + RR IK A + GV+ + V EL F + T +R + + R +YF+
Sbjct: 195 DVLAGMNQLWRRNIKKAAKEGVEVTSTDVPGEELAAFHDLYVHTAERDHFTPRPLSYFRT 254
Query: 227 LMTTYG 232
++ G
Sbjct: 255 MLDALG 260
>ref|YP_001278273.1| Methicillin resistance protein [Roseiflexus sp. RS-1]
gb|ABQ92323.1| Methicillin resistance protein [Roseiflexus sp. RS-1]
Length = 366
Score = 63.9 bits (154), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 59/231 (25%), Positives = 101/231 (43%), Gaps = 27/231 (11%)
Query: 18 DSFVKEHQQISVLQGSDWAKIKNQ--WQNE-RIGIYKEEKQVASLSLLIKLLPLGRSIIY 74
D+FV H +LQ S W +K + W+ R + E Q +L+L + L L S +Y
Sbjct: 30 DAFVAAHPDGHLLQSSRWGALKGRFGWKPHLRAVVAGETIQAGALALEKQRLAL--SALY 87
Query: 75 IPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAA 134
+PRGP+ D + A + + G+ ++A+F++ +P I E+ P A
Sbjct: 88 VPRGPLFSG-DPSIDALLLDDMIRLGRRRRAVFVRIEPNI----------TEDDPRAATL 136
Query: 135 IKNLQEAGVHWTGLTMEIADSIQPRFQANI---YTQENLEMQFPKHTRRLIKDAKQRGVK 191
L + ++ IQPR ++ E L K R IK A + GV+
Sbjct: 137 HSFLLD-------RALQPTPPIQPRSTIHLDLTPEPERLLAGMSKGHRADIKRALREGVE 189
Query: 192 TYRV-SQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
+ ++L F I+ T R ++ + AY+ ++ +GD L LA+
Sbjct: 190 VREGGTPADLDAFYAIMQATSARAGFAIHSPAYYAAVLELFGDAVRLWLAE 240
>ref|NP_627788.1| hypothetical protein SCO3593 [Streptomyces coelicolor A3(2)]
emb|CAB45460.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]
Length = 397
Score = 63.2 bits (152), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 72/137 (52%), Gaps = 6/137 (4%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLP-LGR 70
IS EH +FV+ + +S LQ W ++K +W++E +G + + V + +L + +P L R
Sbjct: 20 ISAAEHLAFVRAQRSVSFLQTPAWGRVKTEWRSESLGWFDGGRLVGAGLVLHRPVPRLER 79
Query: 71 -SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
++ Y+P GPV+D+ D+ A+ + L Y K + A I+ P + ++ +E ++
Sbjct: 80 FTLAYLPEGPVIDWTG-DIDAW-LDPLAAYLKARGAFAIRLGPPVCTDVWS--ADEIKEG 135
Query: 130 LALAAIKNLQEAGVHWT 146
+A + L WT
Sbjct: 136 IADPGTRRLTGLPTRWT 152
>gb|AAM80555.1| StaO [Streptomyces toyocaensis]
Length = 388
Score = 62.0 bits (149), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 58/248 (23%), Positives = 108/248 (43%), Gaps = 36/248 (14%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLP-LGR 70
IS +H +FV+ + +S LQ W ++K +W++E +G + + V + +L + +P L R
Sbjct: 22 ISAADHLAFVRAQRSVSFLQTPAWGRVKTEWRSESLGWFDGPRLVGAGLVLHRPVPRLDR 81
Query: 71 -SIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEE--- 126
++ Y+P GPV+D+ + + L Y K A I+ P ++ + Q ++
Sbjct: 82 YTLAYLPEGPVIDWSSE--IGAWLDPLAAYLKEHGAFAIRLGPPVVTDTWDATQIKDGIA 139
Query: 127 --------------EKPLALAAIKNLQEAGVHWTGLTMEIADSI---QPRFQANI----Y 165
+ P+ L++AG W L D P+F+ +
Sbjct: 140 DPQIRRLTDMPGRWDDPVGARVSSQLKDAG--W--LPQNPLDGFGVGHPQFKYVLPLAGR 195
Query: 166 TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQS---ELHKFSKIVSLTEKRKNISLRNEA 222
T++ L + RR IK + + GV+ VS +L F + T +R + R +
Sbjct: 196 TEDELLRGMNQQWRRNIKKSAKEGVEVT-VSDGGPEDLKAFHDLYVHTAERDRFTPRPLS 254
Query: 223 YFQKLMTT 230
YF+ + T
Sbjct: 255 YFETMFTA 262
>ref|YP_001542863.1| Methicillin resistance protein [Herpetosiphon aurantiacus ATCC
23779]
gb|ABX02735.1| Methicillin resistance protein [Herpetosiphon aurantiacus ATCC
23779]
Length = 354
Score = 61.6 bits (148), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 53/225 (23%), Positives = 108/225 (48%), Gaps = 22/225 (9%)
Query: 27 ISVLQGSDWAKIKNQ--WQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYL 84
+ +LQ ++W ++K Q WQ +RI IY + A +L + G + Y+PRGPV
Sbjct: 23 VHLLQRAEWGQLKAQFGWQPQRIAIYNQHGFCAGAQVLWRS-QYGLRVAYVPRGPVWS-A 80
Query: 85 DRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVH 144
D+ +++L+ + + A F++ +P +L A ++ L LA + +
Sbjct: 81 DQAANRLLLQSLERLARKRWAAFLRLEPNLLDAGAA---DQLHSELLLAGYEQSR----- 132
Query: 145 WTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRV--SQSELHK 202
+M+ + SI Q + +L+ Q K R ++ A+++GV + RV ++++L +
Sbjct: 133 ----SMQPSASIHLDLQPEL---ASLQAQCSKGHRADVRRAERQGV-SIRVGTTEADLDQ 184
Query: 203 FSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQK 247
F I+ T +R N + + Y+ + +G A++ I ++
Sbjct: 185 FYAIMQATSQRANFGIHSREYYAQAWRLFGGDQADGAARLLIAER 229
>ref|YP_138883.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme, putative [Streptococcus thermophilus LMG 18311]
gb|AAV60068.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme, putative [Streptococcus thermophilus LMG 18311]
Length = 419
Score = 61.2 bits (147), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 99/233 (42%), Gaps = 20/233 (8%)
Query: 174 FPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGD 233
F +R +K VKT + + +L +F I+S T +RK S+ YFQ L +G
Sbjct: 185 FSPSLKRDLKKFTALNVKTEELDEHQLDQFYDILSRTAERKGFSVHPLVYFQNLKKYFGK 244
Query: 234 KAYLHLAKVNIP---QKLDQYRQQLILINQDITRTQAHQKKRLK----KLEDQKASLERY 286
A LA ++ P LD+ Q QD+ + QKKR K EDQ S +
Sbjct: 245 SAKFMLAYLDCPAYLAYLDENIQSFEAKIQDL--KEGPQKKRTKGQIADAEDQLRSYYKR 302
Query: 287 ITEFEGF---TDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDA 343
+ +F+ + TD+ P ++ L + YG + Y G ++ + F LL+ + + A
Sbjct: 303 LEQFKSYQIKTDKLP----LSAYLFMDYGPEIVSFYGGNDEAYLNFGGAVLLHWEMLKYA 358
Query: 344 YQDGIIWANMGGV----EGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI 392
N G S G FK F +E +G F+ ++P Y I
Sbjct: 359 KSKSKKHFNFYGTIETEAASSGKGNFNFKRQFGGQLETLVGSFDKTLNPFYDI 411
>ref|YP_140766.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme, putative [Streptococcus thermophilus CNRZ1066]
gb|AAV61951.1| peptidoglycan branched peptide synthesis protein, alanine adding
enzyme, putative [Streptococcus thermophilus CNRZ1066]
Length = 419
Score = 60.8 bits (146), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 97/233 (41%), Gaps = 20/233 (8%)
Query: 174 FPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGD 233
F +R +K VKT + + +L +F I+S T +RK S+ YFQ L +G
Sbjct: 185 FSPSLKRDLKKFTALNVKTEELDEHQLDQFYDILSRTAERKGFSVHPLVYFQNLKKFFGK 244
Query: 234 KAYLHLAKVNIP---QKLDQYRQQLILINQDITRTQAHQKKRLK-KLEDQKASLERYITE 289
A LA ++ P LD+ Q QD+ + QKKR K ++ D + L Y
Sbjct: 245 SAKFMLAYLDCPAYLAYLDENIQSFEAKIQDL--KEGPQKKRTKGQIADAEDQLRSYYKR 302
Query: 290 FEGF------TDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDA 343
E F TD+ P ++ L + YG + Y G ++ + F LL+ + + A
Sbjct: 303 LEQFKSYQIKTDKLP----LSAYLFMDYGPEIVSFYGGNDEAYLNFGGAVLLHWEMLKYA 358
Query: 344 YQDGIIWANMGGV----EGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI 392
N G S G FK F +E +G F+ ++P Y I
Sbjct: 359 KSKSKKHFNFYGTIETEAASSGKGNFNFKRQFGGQLETLVGSFDKTLNPFYDI 411
>ref|YP_819882.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus
thermophilus LMD-9]
gb|ABJ65686.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus
thermophilus LMD-9]
Length = 381
Score = 59.7 bits (143), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 97/233 (41%), Gaps = 20/233 (8%)
Query: 174 FPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGD 233
F +R +K VKT + + L +F I+S T +RK S+ YFQ L +G
Sbjct: 147 FSPSLKRDLKKFTALNVKTEELDEHRLDQFYDILSRTAERKGFSVHPLVYFQNLKKYFGK 206
Query: 234 KAYLHLAKVNIP---QKLDQYRQQLILINQDITRTQAHQKKRLK----KLEDQKASLERY 286
A LA ++ P LD+ Q QD+ + QKKR K EDQ S +
Sbjct: 207 SAKFMLAYLDCPAYLAYLDENIQSFEAKIQDL--KEGPQKKRTKGQIADAEDQLRSYYKR 264
Query: 287 ITEFEGF---TDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDA 343
+ +F+ + TD+ P ++ L + YG + Y G + + F LL+ + + A
Sbjct: 265 LEQFKSYQIKTDKLP----LSAYLFMDYGPEIVSFYGGNEEAYLNFGGAVLLHWEMLKYA 320
Query: 344 YQDGIIWANMGGV----EGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI 392
N G S G FK F +E +G F+ ++P Y I
Sbjct: 321 KSKSKKHFNFYGTIETEAASSGKGNFNFKRQFGGQLETLVGSFDKTLNPFYDI 373
>ref|NP_825052.1| hypothetical protein SAV_3875 [Streptomyces avermitilis MA-4680]
dbj|BAC71587.1| hypothetical protein [Streptomyces avermitilis MA-4680]
Length = 180
Score = 58.9 bits (141), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 9/117 (7%)
Query: 12 ISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKE-------EKQVASLSLLIK 64
I+ EEH +FV S +Q W +K W+ E +G Y E + V + +L +
Sbjct: 8 ITREEHLAFVASRPSASHMQVPSWGDVKPDWRAESLGWYDEGDGGARGGRLVGAGLVLFR 67
Query: 65 LLP-LGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYA 120
LP L R + Y+P GPV+D+ DL + + + Y K + A +K P +++++++
Sbjct: 68 PLPKLKRYLAYLPEGPVIDWYVPDLDRW-LDPMLAYLKARGAFSVKMGPPVVVRRWS 123
>ref|YP_819233.1| Peptidoglycan interpeptide bridge formation enzyme [Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293]
gb|ABJ62860.1| Peptidoglycan interpeptide bridge formation enzyme [Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293]
Length = 345
Score = 52.0 bits (123), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 92/374 (24%), Positives = 148/374 (39%), Gaps = 64/374 (17%)
Query: 16 EHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEE--KQVASLSLLIKLLPLGRSII 73
++ FV+E+ + V Q W ++K+ W + I +Y E K A++S+L G+ +
Sbjct: 14 DYQQFVRENPRGQVTQDPLWGELKSNWGH--IYVYHETDGKIDAAMSVLTVEAVPGKLLA 71
Query: 74 YIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALA 133
Y+ RGPV D D DL+ +M ++ DP + AL Q+ + A
Sbjct: 72 YVGRGPVADVEDIDLIK-SMINEALTALPDNVFLVRMDPEVSYSD-ALNQKYLD-----A 124
Query: 134 AIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTY 193
K + H G +IQPR +Y D + G K
Sbjct: 125 GFKTRNKQVKHMHG-------NIQPRKNVVLYY-----------------DGRGEGAKPI 160
Query: 194 RVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQ 253
++ EL ++ K +N R A+ + T GD + +I D Y
Sbjct: 161 -TNEDEL-----MLHFKPKVRNDIRR--AFRDGVTVTSGD------GEEDIRALFDTYVS 206
Query: 254 QLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGN 313
+ + IT R++KL Y+ +E DQ V+A L SYG+
Sbjct: 207 --MAKSHGITHRPIDYFLRMQKLWAGTGLFRVYLAHYE---DQ-----VIASGLGFSYGD 256
Query: 314 VMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DGLTKFKANF 371
+ +YAG +F K + + + + G + + GG+ G D DGL KFK F
Sbjct: 257 EIWYMYAGSYREFGKHNAPAAIQYEMLKWGLELGKVEYDFGGI-GEFDNSDGLYKFKHEF 315
Query: 372 A--PTIEEFIGEFN 383
A E+IGE +
Sbjct: 316 AYHDPHAEYIGELD 329
>ref|ZP_01544459.1| peptidoglycan branched peptide synthesis protein [Oenococcus oeni
ATCC BAA-1163]
gb|EAV39284.1| peptidoglycan branched peptide synthesis protein [Oenococcus oeni
ATCC BAA-1163]
Length = 339
Score = 48.1 bits (113), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 79/384 (20%), Positives = 153/384 (39%), Gaps = 88/384 (22%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV-ASLSLL-IKLLPLGRSI 72
++++ FV+ + + Q + W +K W + + E Q+ A++++L I+ +P G+ +
Sbjct: 12 KKYNDFVRTNWRGQATQDTLWGALKANWGHLYVYHENESGQIDAAMAVLTIEAVP-GKLL 70
Query: 73 IYIPRGPVMDYLDRDLV-AFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLA 131
Y PRGP+ D+ + +LV + + L+ ++ DP ++ Q + A
Sbjct: 71 AYSPRGPIADFENIELVDSLVNEALE--ALPNNVFLLRMDPEVIYDQ----DLNDRYQAA 124
Query: 132 LAAIKNLQEAGVHWTGLTMEIADSIQPRFQA-----NIYTQENLEMQFPKHTRRLIKDAK 186
+N+Q +H +IQPR +I +++L F ++ R I+ A
Sbjct: 125 GYQTRNVQIKSMH---------GNIQPRKNMVLSYKDIKNEDDLMTHFKRYYRTQIRHAI 175
Query: 187 QRGVKT-YRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIP 245
+ G+ + S+ + F + + + I+ R + YF
Sbjct: 176 KDGMTVDFGHSREFVDDFYETYVMMANAQQITYRPKEYFY-------------------- 215
Query: 246 QKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAG 305
R+ L + ++ F+G +V +G
Sbjct: 216 --------------------------RMSDLFASTGLFKIFLAHFQG-------HIVASG 242
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DG 363
I ++G+ + +YAG + + K Y YLL + + + GGV G+ D DG
Sbjct: 243 I-GFAHGDEIWYMYAGSDRKYSKHYGPYLLQWEMTKWGLSLQKAEYDFGGV-GAFDPSDG 300
Query: 364 LTKFKANF----APTIEEFIGEFN 383
L +FK F AP E+IGE +
Sbjct: 301 LYRFKHGFTYKDAP--REYIGEVD 322
>ref|YP_001728723.1| FemX [Leuconostoc citreum KM20]
gb|ACA83279.1| FemX [Leuconostoc citreum KM20]
Length = 345
Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 85/385 (22%), Positives = 140/385 (36%), Gaps = 94/385 (24%)
Query: 20 FVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGP 79
FV+ + V Q W ++K+ W + + + A LS+L G+ + Y RGP
Sbjct: 18 FVRRDPRGQVTQDPLWGELKSNWGHVYVYHETNGRIDAVLSVLTVEAVTGKLLGYAGRGP 77
Query: 80 VMDYLD----RDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAAI 135
+ D D + ++ + L D I+ DP E P A
Sbjct: 78 IADIDDIDLIKSMIEEALTALPD-----NVFLIRMDP--------------EVPYTPARN 118
Query: 136 KNLQEAG-VHWTGLTMEIADSIQPRFQANIY------------TQENLEMQFPKHTRRLI 182
Q AG V + +IQPR +Y +++L + F + R I
Sbjct: 119 TAYQNAGFVTRNRDITHMHGNIQPRKNVVLYYDGRGEGAKPITNEDDLMLHFKRDYRNQI 178
Query: 183 KDAKQRGVK-TYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAK 241
+ A + GV T S++++ F + + ++I+ R YF
Sbjct: 179 RRAAKDGVTVTSGDSEADVRAFFETYVMMATAQSITHRPIDYFL---------------- 222
Query: 242 VNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEV 301
R++KL + ++ FEG V
Sbjct: 223 ------------------------------RMQKLWQGTGLFKVFLAHFEG-------HV 245
Query: 302 VVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSL- 360
V +GI SYG+ + +YAG + + K Y Y + ++ Q G + + GGV +
Sbjct: 246 VASGI-GFSYGDEIWYMYAGSDRRYAKHYGPYAVQWHMLQWGLALGKVAYDFGGVGDFVP 304
Query: 361 DDGLTKFKANFA--PTIEEFIGEFN 383
DGL KFK FA E+IGE +
Sbjct: 305 TDGLYKFKHGFAYHDPHAEYIGELD 329
>ref|YP_810970.1| Peptidoglycan interpeptide bridge formation enzyme [Oenococcus oeni
PSU-1]
gb|ABJ57305.1| Peptidoglycan interpeptide bridge formation enzyme [Oenococcus oeni
PSU-1]
Length = 339
Score = 45.8 bits (107), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 79/384 (20%), Positives = 151/384 (39%), Gaps = 88/384 (22%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIYKEEKQV-ASLSLL-IKLLPLGRSI 72
++++ FV+ + + Q + W +K W + + E Q+ A++++L I+ +P G+ +
Sbjct: 12 KKYNDFVRTNWRGQATQDTLWGALKANWGHLYVYHENESGQIDAAMAVLTIEAVP-GKLL 70
Query: 73 IYIPRGPVMDYLDRDLV-AFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLA 131
Y PRGP+ D+ + +LV + + L+ ++ DP ++ Q + A
Sbjct: 71 AYSPRGPIADFENIELVDSLVNEALE--ALPNNVFLLRMDPEVIYDQ----DLNDRYQAA 124
Query: 132 LAAIKNLQEAGVHWTGLTMEIADSIQPRFQA-----NIYTQENLEMQFPKHTRRLIKDAK 186
+N+Q +H +IQPR +I +++L F + R I+ A
Sbjct: 125 GYQTRNVQIKSMH---------GNIQPRKNMVLSYKDIKNEDDLMTHFKRDYRTQIRHAI 175
Query: 187 QRGVKT-YRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIP 245
+ G+ + S+ + F + + + I+ R + YF
Sbjct: 176 KDGMTVDFGHSREFVDDFYETYVMMANAQQITYRPKEYFY-------------------- 215
Query: 246 QKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEEVVVAG 305
R+ L + ++ F+G +V +G
Sbjct: 216 --------------------------RMSDLFASTGLFKIFLAHFQG-------HIVASG 242
Query: 306 ILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGSLD--DG 363
I ++G+ + +YAG + + K Y YLL + + + GGV G D DG
Sbjct: 243 I-GFAHGDEIWYMYAGSDRKYSKHYGPYLLQWEMTKWGLSLQKAEYDFGGV-GVFDPSDG 300
Query: 364 LTKFKANF----APTIEEFIGEFN 383
L +FK F AP E+IGE +
Sbjct: 301 LYRFKHGFTYKDAP--REYIGEVD 322
>ref|NP_972343.1| femAB family protein [Treponema denticola ATCC 35405]
gb|AAS12254.1| femAB family protein [Treponema denticola ATCC 35405]
Length = 354
Score = 42.4 bits (98), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 79/380 (20%), Positives = 140/380 (36%), Gaps = 85/380 (22%)
Query: 45 ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKK 104
ERIG +++ K + ++ +P + I +M + ++ LK+ K +
Sbjct: 40 ERIGFFEDGKLKNGIQIIFSKIPKTNYTVGIASKTIMPEQEH------IEALKEAAKKHR 93
Query: 105 ALFIKYDPAILL---KQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRFQ 161
A+FIK +P + K +L + + A I++ ++ L A + +P F+
Sbjct: 94 AVFIKLEPDVFSPVQKDNSLEETSSDAGFLEAPIEDKKKI------LLKNGAKNGKPFFE 147
Query: 162 ANIY------TQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSE-LHKFSKIVSLTEKRK 214
+ T+E+L F TR I+ A+++GV S E + + +++ T KR+
Sbjct: 148 KYNFLLNIEKTEEDLLASFHSKTRYNIRLAEKKGVSIIEKSTEEGMEDYIRLMEETTKRQ 207
Query: 215 NISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLK 274
N YF R+ + +D R
Sbjct: 208 GFFNHNGEYF---------------------------RRMFKIFPKDTLRI--------- 231
Query: 275 KLEDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL 334
F Y +EV+ A IL + + Y ++ ++ P L
Sbjct: 232 ------------------FEAVYGDEVLTAWIL-FKFNGKLYYPYGASSNSHRELMPNNL 272
Query: 335 LYPNVFQDAYQDGIIWANMGGVEGSLDD------GLTKFKANFAPTIEEFIGEFNLPVSP 388
+ Q + ++ G G D G KFKA + P + E+IG F+ P
Sbjct: 273 IMWKAIQYGKKLNCSVFDLWGCLGPNPDTENSWYGFHKFKAGYNPQLVEYIGTFDFVYKP 332
Query: 389 -LYHIANTMYKIRK-QLKNK 406
+Y + N KIR LKNK
Sbjct: 333 FMYKLFNLADKIRWIILKNK 352
>ref|YP_004713.1| murM [Thermus thermophilus HB27]
gb|AAS81086.1| murM [Thermus thermophilus HB27]
Length = 340
Score = 41.2 bits (95), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 50/242 (20%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI 72
E + V S LQ W ++K W+ R + E VA+ +L+K P G +
Sbjct: 11 EAWNRLVSGFAITSPLQSWGWGEVKRTTGWEPRRFLLLGGEGPVAAAQVLLKAAPGGLRL 70
Query: 73 IYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLAL 132
Y PRGP + L+ DL + + G+ +A + +P E P L
Sbjct: 71 AYAPRGPALHRLE-DLP----QVARALGRALRATHLVLEP------------EAGLPAHL 113
Query: 133 AAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKT 192
A + + GL +E + IQP +L + + L+K K+ +
Sbjct: 114 PAPR--------FPGLLLE--EPIQP--------AHSLWLDLTQGEEALLKGMKEMHRRN 155
Query: 193 YRVS----------QSELHKFSKIVSLTEKRKNISLRNEAYFQ---KLMTTYGDKAYLHL 239
R++ + +F ++ + T +R + +EAY++ K M +A+L L
Sbjct: 156 ARLALKRVALSVEGEEAFAEFYRLFTETNRRARLLQHDEAYYRAVLKEMNQPLGEAFLAL 215
Query: 240 AK 241
A+
Sbjct: 216 AR 217
>ref|YP_144369.1| FemA-related protein [Thermus thermophilus HB8]
dbj|BAD70926.1| FemA-related protein [Thermus thermophilus HB8]
Length = 340
Score = 41.2 bits (95), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 50/242 (20%)
Query: 15 EEHDSFVKEHQQISVLQGSDWAKIK--NQWQNERIGIYKEEKQVASLSLLIKLLPLGRSI 72
E + V S LQ W ++K W+ R + E VA+ +L+K P G +
Sbjct: 11 EAWNRLVSGFAITSPLQSWGWGEVKRTTGWEPRRFLLLGGEGPVAAAQVLLKAAPGGLRL 70
Query: 73 IYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLAL 132
Y PRGP + L+ DL + + G+ +A + +P E P L
Sbjct: 71 AYAPRGPALHRLE-DLP----EVARALGRALRATHLVLEP------------EAGLPAHL 113
Query: 133 AAIKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKT 192
A + + GL +E + IQP +L + + L+K K+ +
Sbjct: 114 PAPR--------FPGLLLE--EPIQP--------AHSLWLDLTQGEEALLKGMKEMHRRN 155
Query: 193 YRVS----------QSELHKFSKIVSLTEKRKNISLRNEAYFQ---KLMTTYGDKAYLHL 239
R++ + +F ++ + T +R + +EAY++ K M +A+L L
Sbjct: 156 ARLALKRVALSVEGEEAFAEFYRLFTETNRRARLLQHDEAYYRAVLKEMNQPLGEAFLAL 215
Query: 240 AK 241
A+
Sbjct: 216 AR 217
>ref|NP_294786.1| FemA-related protein [Deinococcus radiodurans R1]
gb|AAF10635.1|AE001957_3 FemA-related protein [Deinococcus radiodurans R1]
Length = 405
Score = 40.4 bits (93), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 55/230 (23%), Positives = 98/230 (42%), Gaps = 23/230 (10%)
Query: 17 HDSFVKEHQQISVLQGSDWAKIKNQWQN--ERIGIYKEEKQVASLSLLIKLLPLGRSIIY 74
+D V E S LQG + + + R I E+ V ++ LL K L G S +Y
Sbjct: 62 YDKVVSEMPITSALQGWGYGEARRVLGQVPMRYLIKDGERTVGAVQLLRKRLVPGLSTLY 121
Query: 75 IPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKPLALAA 134
PRGP ++ L+ L AF K T + +K +P Y G+ + + L AA
Sbjct: 122 APRGPAIESLEL-LPAFADAVRKVAKPTD--VLLKIEPPY---PYLAGENDHGESLP-AA 174
Query: 135 IKNLQEAGVHWTGLTMEIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYR 194
+ + T+ +AD + ++++L RR ++ A++ GV R
Sbjct: 175 FGPFRRSETEQPEHTI-VADLRR--------SEDDLFSGLHSMARRNVRTAQKLGVVAGR 225
Query: 195 VSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLM---TTYGDKAYLHLAK 241
+ F +I + T +R + Y++ ++ YG +AY+ L++
Sbjct: 226 --DDDFEAFWEIFTATNERAKLGAFPREYYETMLREANAYGGEAYIVLSR 273
>ref|YP_001514886.1| hypothetical protein AM1_0520 [Acaryochloris marina MBIC11017]
gb|ABW25572.1| hypothetical protein AM1_0520 [Acaryochloris marina MBIC11017]
Length = 358
Score = 40.0 bits (92), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 296 QYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGG 355
+Y +E++ AG+ S G +++ L G + K P L + A Q G ++GG
Sbjct: 229 EYQDEIISAGLYSECSG-IVQGLLGGTTPEGLKLSPTSLEFYQTSLWAKQRGNTILHLGG 287
Query: 356 VEGSLDDGLTKFKANFAPTIEEF 378
G +DGL ++KANF+ EF
Sbjct: 288 GVGCSEDGLYQYKANFSKQRHEF 310
>ref|NP_825051.1| hypothetical protein SAV_3874 [Streptomyces avermitilis MA-4680]
dbj|BAC71586.1| hypothetical protein [Streptomyces avermitilis MA-4680]
Length = 188
Score = 38.9 bits (89), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 49/239 (20%), Positives = 87/239 (36%), Gaps = 57/239 (23%)
Query: 168 ENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKL 227
++L + RR IK A++ GVK + +L F + + T R R YFQ++
Sbjct: 2 DDLHRGLNQQWRRNIKKAEKAGVKVVQGGYHDLPAFYTLYTETAARDRFIPRPLPYFQRM 61
Query: 228 MTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYI 287
T + D +R +L L AH
Sbjct: 62 WTALTAE--------------DPHRMRLYL---------AHHGG---------------- 82
Query: 288 TEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDG 347
EV+ A + ++ G + Y ++ P + + DA+ G
Sbjct: 83 ------------EVLSAATM-LTVGTHVWYSYGASTSRRREAQPNNAVQWRMLTDAHARG 129
Query: 348 IIWANMGGVEGSLDD-----GLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIRK 401
++ G+ +L+D GL +FK E++GE++ P++ L H A +Y R+
Sbjct: 130 AEVYDLRGITDTLEDSNHLLGLLRFKVGTGGEAAEYLGEWDFPLNRLLHKALDLYMARR 188
>ref|ZP_02182777.1| hypothetical protein FBALC1_08118 [Flavobacteriales bacterium
ALC-1]
gb|EDP70709.1| hypothetical protein FBALC1_08118 [Flavobacteriales bacterium
ALC-1]
Length = 350
Score = 38.9 bits (89), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 20/79 (25%), Positives = 42/79 (53%)
Query: 300 EVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMGGVEGS 359
+ ++ G + I G++++ +G+++ + P L+ V A +G N+GG GS
Sbjct: 226 QTIIGGAIFIKKGDLVQYHLSGLSEAYFDLNPIKLIIDEVRIRATHEGYKHFNLGGGRGS 285
Query: 360 LDDGLTKFKANFAPTIEEF 378
+D L +FK+ F+ ++F
Sbjct: 286 SEDSLFRFKSGFSKNFKKF 304
>ref|ZP_02838884.1| hypothetical protein AchlDRAFT_3494 [Arthrobacter chlorophenolicus
A6]
gb|EDS61262.1| hypothetical protein AchlDRAFT_3494 [Arthrobacter chlorophenolicus
A6]
Length = 118
Score = 38.5 bits (88), Expect = 0.98, Method: Composition-based stats.
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 42 WQNERIGIYKEEKQVASLSLLIKLLPLG-RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYG 100
W +R+ + E V + LL++ LPL R+++YIPRGP+ D V + +L D+
Sbjct: 4 WSVDRVLLKDGETTVGAAQLLVRPLPLPFRALVYIPRGPMCSVADTQAV---LNSLADHA 60
Query: 101 KTK 103
+
Sbjct: 61 AIR 63
>ref|XP_001196888.1| PREDICTED: similar to mollusk-derived growth factor; MDGF, partial
[Strongylocentrotus purpuratus]
ref|XP_788317.2| PREDICTED: similar to mollusk-derived growth factor; MDGF, partial
[Strongylocentrotus purpuratus]
Length = 531
Score = 37.7 bits (86), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 8/64 (12%)
Query: 277 EDQKASLERYITEFEGFTDQYPEEVVVAGILSISY------GNVMEMLYAGMNDDFKKFY 330
Q+ +L+ YI + FTDQYP + V I+S S V + +Y GM DF+K Y
Sbjct: 308 SSQEHTLQEYIRVLKDFTDQYPNDFVGGKIISSSLRYPLNKTLVRDQVYLGM--DFRKKY 365
Query: 331 PQYL 334
P++
Sbjct: 366 PEFF 369
>gb|ABP51932.1| AcrV [Aeromonas veronii bv. sobria]
Length = 361
Score = 37.4 bits (85), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 13/121 (10%)
Query: 111 DPAILLKQYALGQEEEEKPLALAAIKNLQEAG-------VHWTG---LTMEIADSIQPRF 160
DPA + +A+GQ + + A+AAIK + E G HWT + + ++ R
Sbjct: 70 DPASINGGWAMGQFQGGQDAAIAAIKGMIERGAKQTPPVTHWTVPEFMLLSLSALTMDRI 129
Query: 161 QANIYTQENLEMQFPKHTRRLIKD--AKQRG-VKTYRVSQSELHKFSKIVSLTEKRKNIS 217
++ T M F + R+ ++D A+ G +K Y V QSE++K S N +
Sbjct: 130 DDDLITTFTGVMAFQDNQRKGLRDELAEMTGELKIYGVIQSEINKVLSAASSQTFNTNFN 189
Query: 218 L 218
L
Sbjct: 190 L 190
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 10, 2008 4:54 AM
Number of letters in database: 2,222,278,849
Number of sequences in database: 6,515,104
Lambda K H
0.318 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 6515104
Number of Hits to DB: 1,707,147,623
Number of extensions: 72560266
Number of successful extensions: 205205
Number of sequences better than 10.0: 357
Number of HSP's gapped: 207635
Number of HSP's successfully gapped: 375
Length of query: 407
Length of database: 2,222,278,849
Length adjustment: 136
Effective length of query: 271
Effective length of database: 1,336,224,705
Effective search space: 362116895055
Effective search space used: 362116895055
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 80 (35.4 bits)