LOCUS       NP_561234                595 aa            linear   BCT 20-JUL-2008
DEFINITION  L-fucose isomerase [Clostridium perfringens str. 13].
ACCESSION   NP_561234
VERSION     NP_561234.1  GI:18309300
DBSOURCE    REFSEQ: accession NC_003366.1
KEYWORDS    .
SOURCE      Clostridium perfringens str. 13
  ORGANISM  Clostridium perfringens str. 13
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (residues 1 to 595)
  AUTHORS   Shimizu,T., Ohtani,K., Hirakawa,H., Ohshima,K., Yamashita,A.,
            Shiba,T., Ogasawara,N., Hattori,M., Kuhara,S. and Hayashi,H.
  TITLE     Complete genome sequence of Clostridium perfringens, an anaerobic
            flesh-eater
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (2), 996-1001 (2002)
   PUBMED   11792842
REFERENCE   2  (residues 1 to 595)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 595)
  AUTHORS   Hattori,M., Yamashita,A., Oshima,K. and Shiba,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2001) Masahira Hattori, Kitasato Institute for
            Life Sciences, Kitasato University; Kitasato 1-15-1, Sagamihara,
            Kanagawa 228-8555, Japan
            (E-mail:hattori@genome.ls.kitasato-u.ac.jp,
            URL:http://genome.ls.kitasato-u.ac.jp, Tel:81-42-778-8194,
            Fax:81-42-778-8193)
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BAB80024.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Clostridium perfringens str. 13"
                     /strain="13"
                     /db_xref="taxon:195102"
     Protein         1..595
                     /product="L-fucose isomerase"
                     /EC_number="5.3.1.25"
                     /calculated_mol_wt=65798
     Region          1..594
                     /region_name="fucI"
                     /note="L-fucose isomerase; Provisional; PRK10991"
                     /db_xref="CDD:104980"
     Region          5..594
                     /region_name="L-fucose_isomerase"
                     /note="L-fucose isomerase (FucIase); FucIase converts
                     L-fucose, an aldohexose, to its ketose form, which
                     prepares it for aldol cleavage (similar to the
                     isomerization of glucose during glycolysis). L-fucose (or
                     6-deoxy-L-galactose) is found in blood group...; cd03556"
                     /db_xref="CDD:63887"
     Site            order(15,17,63,67,71,74,129,174,193,196,203,206..209,213,
                     290..291,297,307..308,312,471,588,594)
                     /site_type="other"
                     /note="hexamer (dimer of trimers) interface"
                     /db_xref="CDD:63887"
     Site            order(16,18,88,90..92,111..112,124,127..128,137,139..141,
                     143,156,183..184,186,306..307,367,369,371,377,444,446,469,
                     471..472,498,521,524,528,555,572..575,577,579,583..584,
                     588)
                     /site_type="other"
                     /note="trimer interface"
                     /db_xref="CDD:63887"
     Site            order(16,88,183,306,341,365,397,444,503,530..531)
                     /site_type="other"
                     /note="substrate binding site"
                     /db_xref="CDD:63887"
     Site            order(341,365,531)
                     /site_type="other"
                     /note="Mn binding site"
                     /db_xref="CDD:63887"
     CDS             1..595
                     /gene="fucI"
                     /locus_tag="CPE0318"
                     /coded_by="NC_003366.1:402971..404758"
                     /note="catalyzes the conversion of the aldose L-fucose
                     into the corresponding ketose L-fuculose"
                     /transl_table=11
                     /db_xref="GeneID:988571"
ORIGIN      
        1 mktypkigir ptidgrqggv resleekamk maqaakklie nslyyadgtp vqcvlasrti
       61 ggsgdagivq qeftgkniva tlsvtpswcy gtetmdldpn tikaiwgfng terpgavyla
      121 aamsgyaqkg ipafkiyghd vqeldddtip vdvqekilsf argaiavgqm kgksyvniga
      181 ssmgiagsqv disffedylg mlvefvdmte ilrrihleif dpieydkaln wikencregi
      241 dinegkdlpd ivkkskvipa dkdwefiakq aiiirdilyr neklgdlgwe eeargrnaia
      301 ggfqgqrqwt dwlpngdfte aimastfdwn gprqvtafat endtlngvsm llgtlltnka
      361 pifsdvrtyw spesvkrvtg keltgkakng iihlinsgas aldgtaaakd kdgnktmkef
      421 wnmtnedvqs clkatdwcra nyeyfrgggf sshfkteael pvtlirvnli kgigptlqia
      481 egytcvided ihqildertd ktwpttwfap nlgecgfetv ydvmnhwgan hgafvhghig
      541 sdlitlasml ripvtlhnvp rerifrpnif egagtkalet adfeicrllg plykk
//