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Treponema denticola Search Results

Record: 1 of 1  
MiniMap IGR0309 IGR0313 IGR0312 IGR0311 IGR0314 IGR0310 IGR0308 TDE0363 TDE0364 TDE0360 TDE0359 TDE0362 gltS,gltP, - TDE0361 TDE0363 TDE0364 TDE0360 TDE0359 TDE0362 gltS,gltP, - TDE0361 Type: tandem, Name: TDE-TR-22 - 22 TDE0363 TDE0364 TDE0360 TDE0359 TDE0362 gltS,gltP, - TDE0361


Gene ID:TDE0361

DNA Molecule Name:
1  

GenBank ID:
42525877

Gene Name:
gltS  gltP  

Definition:
sodium/glutamate symporter

Cellular Location:
Inner membrane, Cytoplasm [Evidence]

Gene Start:
406129

Gene Stop:
407499

Gene Length:
1449

Molecular Weight*:
52634

pI*:


Net Charge*:


EC:
 

Functional Class:
Transport and binding proteins; Amino acids, peptides, and amines  

Gene Ontology:

Pathway: pathway table

Secondary Evidence:
Navarro F, Martín-Figueroa E, Candau P, Florencio FJ.
Ferredoxin-dependent iron-sulfur flavoprotein glutamate synthase (GlsF) from the Cyanobacterium synechocystis sp. PCC 6803: expression and assembly in Escherichia coli.
Arch Biochem Biophys. 2000 Jul;379(2):267-76.
PMID: 10898944

Quintero MJ, Montesinos ML, Herrero A, Flores E.
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Genome Res. 2001 Dec;11(12):2034-40.
PMID: 11731493

Hosie AH, Allaway D, Poole PS.
A monocarboxylate permease of Rhizobium leguminosarum is the first member of a new subfamily of transporters.
J Bacteriol. 2002 Oct;184(19):5436-48.
PMID: 12218

Comment:
Other related symporters are TDE0130 and TDE2336, and in addition, other 'glt' genes are TDE1594, TDE2167, TDE0204, TDE0407.

View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search

TDE0361 has no significant similarity (BLAST p-value < 1e-03) to a Treponema pallidum gene.

TDE0361 has no significant similarity (BLAST p-value < 1e-3) to a Borrelia burgdorferi gene.


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|42525877|ref|NP_970975.1|  transporter, putative [Trepone...   825   0.0  
 gi|156864521|gb|EDO57952.1|  hypothetical protein CLOL250_01...   292   3e-77
 gi|154484877|ref|ZP_02027325.1|  hypothetical protein EUBVEN...   283   1e-74
 gi|150388602|ref|YP_001318651.1|  sodium/glutamate symporter...   281   5e-74
 gi|148324007|gb|EDK89257.1|  ESS family glutamate:sodium (Na...   270   1e-70
 gi|118444359|ref|YP_878176.1|  sodium/glutamate symporter [C...   266   3e-69
 gi|106886913|ref|ZP_01354239.1|  sodium/glutamate symporter ...   259   2e-67
 gi|90410464|ref|ZP_01218480.1|  Putative sodium/glutamate sy...   251   7e-65
 gi|59713665|ref|YP_206440.1|  sodium/glutamate symport carri...   251   8e-65
 gi|54309273|ref|YP_130293.1|  Putative sodium/glutamate symp...   250   1e-64


COGS Summary:  COGS Search
BeTs to clades of COG0786
COG name: Na+/glutamate symporter
Functional Class:  E
The phylogenetic pattern of COG0786 is -------------cefgh-nu-----
Number of proteins in this genome belonging to this COG is


Blocks Summary:  Blocks Search


ProDom Summary:  Protein Domain Search

Residues 305 to 449 match (3e-32) PD:PD017853 which is described as COMPLETE PROTEOME GLUTAMATE SODIUM/GLUTAMATE SYMPORT PERMEASE CARRIER SYMPORTER GLTS SODIUM

Residues 18 to 206 match (2e-18) PD:PD017853 which is described as COMPLETE PROTEOME GLUTAMATE SODIUM/GLUTAMATE SYMPORT PERMEASE CARRIER SYMPORTER GLTS SODIUM

Paralogs:  Local Blast Search

TDE0361 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search

Residues 3 to 425 (E-value = 2e-95) place TDE0361 in the Glt_symporter family which is described as Sodium/glutamate symporter (PF03616)


Structural Feature(s):
Feature Type  Start  Stop
transmembrane  
11  
28
transmembrane  
37  
54
transmembrane  
68  
85
transmembrane  
96  
114
transmembrane  
119  
137
transmembrane  
156  
175
transmembrane  
276  
293
transmembrane  
304  
321
transmembrane  
343  
360
transmembrane  
365  
382
transmembrane  
397  
414
transmembrane  
430  
450

Top PDB Hits:
No PDB hits found using the nr database and 5 rounds of Psi-BLAST (E-value < 0.01)

Gene Protein Sequence:
MVIHMNMYQSLGFAIAWLLVGRFIKAKFEFFQKYCIPAPIVGGFLFALIS
LALHVTRVLDFEFDTTLQTYWMVMFFTSVGYNAGFSILRDGGKKVFVFLA
VAIVFAILQNVVAQGAARLINFSPMLAVMLGSTSFTGGFGTAASFAPIVD
PENTLGALSLAVAVPTFGSLISSILGGPVGNRLIKKYGLQPSNADESVRI
DESGNIIKTKKVVKKVEAVHPSFIKRLFFNPTKGREEGQEVVTVQEEVIH
EASAKGEVDNSTTSSEKHLSSEKLLMSFMLLVLASGFGLFVTNHLNSLSP
KFKFPIYIGAMICAAIIRNIADTSKKFKVNMDEIDALGNISLNMFLALAL
VSLKLWQLVSLAIPLMIILSAQIVLLYLYTRFVTFKVMGGDYDAAVITAG
HIGFGFAATPNAMANMGSICEKYGYSKIAFFVVPIVGSLFIDFFNIMIIG
ITIGLVD

Gene Nucleotide Sequence:  Sequence Viewer
ATGGTAATTCATATGAATATGTACCAGTCGCTCGGCTTTGCAATCGCTTG
GTTGCTTGTCGGACGATTCATTAAGGCGAAGTTTGAGTTTTTTCAAAAGT
ATTGTATACCTGCCCCGATAGTGGGCGGCTTTTTGTTTGCGCTGATTTCG
TTAGCACTTCACGTAACAAGGGTACTCGACTTCGAATTTGACACAACCCT
GCAAACCTATTGGATGGTGATGTTTTTTACTTCTGTGGGTTATAATGCAG
GGTTTTCGATTTTAAGAGACGGCGGGAAAAAAGTTTTTGTCTTTTTGGCT
GTAGCTATCGTTTTTGCTATTTTGCAAAACGTTGTAGCTCAAGGAGCCGC
AAGGCTTATAAACTTTAGTCCGATGCTCGCCGTCATGCTGGGTTCAACAT
CCTTTACAGGGGGGTTCGGTACAGCGGCCTCCTTTGCACCGATTGTTGAT
CCGGAAAACACTCTGGGAGCCTTATCCCTCGCAGTAGCCGTTCCCACCTT
CGGCTCTTTGATAAGCTCCATCTTAGGCGGTCCCGTCGGAAACCGTCTGA
TAAAAAAATACGGCTTACAGCCTTCAAATGCCGATGAAAGCGTAAGAATT
GATGAATCGGGAAACATAATAAAAACAAAAAAAGTTGTTAAGAAAGTAGA
AGCGGTTCATCCGAGCTTTATAAAGCGGCTCTTCTTTAATCCCACAAAGG
GCAGGGAAGAGGGGCAAGAAGTCGTAACGGTTCAGGAGGAAGTTATTCAT
GAAGCCTCGGCAAAAGGTGAAGTAGATAACTCGACAACCAGTTCTGAAAA
GCATCTTAGCAGTGAAAAGCTTTTAATGTCATTTATGCTTTTAGTTCTGG
CCTCAGGTTTTGGTCTTTTTGTTACCAATCATCTTAATTCGTTGTCGCCC
AAATTTAAATTCCCCATTTATATCGGGGCGATGATTTGTGCTGCCATTAT
ACGGAACATTGCAGATACCTCAAAAAAATTCAAGGTAAATATGGATGAAA
TTGATGCACTCGGAAATATTTCTTTGAATATGTTTTTGGCTTTAGCTCTT
GTTTCGCTGAAACTTTGGCAGCTTGTAAGTTTGGCTATCCCTCTGATGAT
TATTTTAAGCGCTCAAATCGTTCTTTTGTATTTGTATACACGCTTTGTTA
CCTTTAAGGTTATGGGCGGAGATTATGACGCTGCGGTCATCACGGCCGGA
CACATTGGGTTCGGTTTTGCCGCAACCCCTAACGCCATGGCTAATATGGG
CTCTATATGCGAAAAATACGGCTATTCAAAGATAGCCTTCTTTGTCGTTC
CTATAGTCGGCTCCTTATTTATTGATTTTTTCAATATAATGATAATTGGT
ATTACCATAGGCTTGGTCGAC

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