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Introduction xiii Acknowledgements xvii Anatomical and neurophysiological phenomena 1 1. Andreas Vesalius: the origins of anatomy 3 2. The localisation of function: early neuroanatomy and neurophysiology 14 3. Convolutions and asymmetries of the brain 22 4. The fissure of Rolando 26 5. The fissure of Sylvius 29 6. Robert Whytt and the stretch reflex 33 7. Notes on the life and work of Marshall Hall 37 8. Erb, Westphal and the tendon reflexes 44 9. Lockhart Clarke's column 48 10. The Schwann cell 51 11. Wallerian degeneration 55 12. Rudolf Ludwig Karl Virchow and myelin 59 13. Remak, father and son 62 Aspects of cerebral disorders 67 14. Aphasia or aphemia 69 15. Early concepts of aphasia; the Broca-Dax controversy 70 16. Development of concepts of aphasia 76 17. Aphasia and Wernicke's arc 81 18. Paul Broca and aphasia 84 19. Von Monakow and diaschisis 90 20. Gerstmann's syndrome 92 21. Early descriptions of sleep paralysis 95 22. Cobb's views on functional illness 98 Demnentias 101 22. Alzheimer's disease 103 24. Pick's disease 108 25. Binswanger's "encephalitis subcorticalis chronica progressiva" 113 26. Alois Alzheimer on Binswanger's disease 116 27. Huntington's chorea 118 Headaches 123 28 Edward Liveing's nerve storms in migraine 125 29 Historical aspects of migraine 138 30 Cervicogenic headache: an early description 156 31 Cluster headache 159 32 Emil Heinrich Du Bois-Reymond 164 33 Hutchinson: an early description of cranial arteritis 168 34 Samuel-Auguste Tissot and migraine 170 35 Nicolaus Petreus Tulpius on headaches 174 3t Gerhard van Swieten and episodic cluster headache 177 Epilepsy and related disorders 179 37. Early accounts of epilepsy 181 38. Sir Victor Horsley: surgery for epilepsy 191 35. Robert Bentley Todd and Todd's paralysis 194 40. West's syndrome: hypsarrhythmic infantile spasms 197 Cerebrospinal fluid and hydrocephalus 199 41. Lumbar puncture 201 42. The cerebral ventricles: seat of the soul 206 43. Early treatment of hydrocephalus 209 44. Domenico Cotugno, C.S.F., and the origins of sciatica 211 Strokes and vascular diseases 213 45. Dechambre and lacunes 215 46. Dejerine and Roussy: the thalamic syndrome 217 47. Brown-Sequard: description of cerebellar haemorrhage; contributions to endocrinology 221 48. The circle of Willis 228 49. Wallenberg's syndrome 233 50. Raynaud's phenomenon 237 Ocular disorders 241 51. Duane's syndrome 243 52. The Marcus Gunn pupil 245 53. A note on heterochromia iridis 248 54. The Holmes-Adie tonic pupil and Hughlings Jackson 249 55. Claude Bernard-Horner's syndrome and Edward Selleck Hare 252 Cranial nerve disorders 257 56. Lucja Frey and the "auriculotemporal syndrome" 259 57. Melkersson's syndrome 261 58. Meniere's disease 263 59. Bell's or Friedreich's palsy 267 60. Sir Charles Bell: a biographical note 272 61. John Locke and the trigeminal neuralgia of the Countess of Northumberland 280 Diseases of the spine, the spinal cord, and radiculopathies 285 62. Subacute combined degeneration of the spinal cord 287 63. Multiple sclerosis: some British contributions 290 64. Quadruplegia and cervical dislocation in the Edwin Smith papyrus 294 65. Samuel Richardson and Forestier's disease 297 66. Sir William Osler on tabes dorsalis (locomotor ataxia) 300 67. Robert Bentley Todd and locomotor ataxia 303 68. Lathyrism 306 Ne aralgias and polyneuropathies 311 69. Octave Landry and the Guillain-Barre-Strohl syndrome 313 70. Silas Weir Mitchell and causalgia 318 71. Bontius and Tulp on beriberi polyneuritis 322 72. Howard Henry Tooth and Charcot-Marie-Tooth disease 324 73. Robert Graves and multiple neuritis 332 74. Sir Henry Head: a note on herpes zoster 335 Physical signs 339 75 A brief history of the reflex hammer 341 76 A brief history of the tuning fork 347 77 Babinski's sign 352 78 Cheyne-Stokes respiration 355 79 Oppenheim's sign 359 80 J.-J. Forst and Lasegue's sign 362 81 Kernig and Brudzinski 365 82. Lhermitte's sign 367 83. Prevost's sign or Vulpian's law: conjugate deviation of the eyes 370 84. Romberg's sign 373 85. Hoffmann and Tinel's sign of formication 375 86. Gowers' sign 378 Genetic, developmental and congenital disorders 381 87. Down's syndrome 383 88. Tay-Sachs disease 386 89. Little's disease 389 90. Bourneville's tuberous sclerosis: "When the cat is away..." 391 91. Arnold Chiari, or Cruveilhier-Cleland-Chiari malformation 395 Movement disorders 399 92. Botulinum toxin 401 93. Wilson's disease 404 94. Athetosis and William Alexander Hammond, a founder of American neurology 413 95. Parkinson's disease 417 96. The Lewy body 429 97. The subthalamic nucleus and Jules Bernard Luys 434 98. Baron Constantin von Economo's encephalitis lethargica 437 99. Thomas Sydenham and Richard Bright on chorea 440 100. Samuel Jones Gee and stereotypic movements caused by apomorphia 448 101. Gilles de la Tourette syndrome 451 102. Romberg on Ekbom's restless legs syndrome 454 Neuromuscular diseases 457 103. Myasthenia gravis 459 104. Some contributions of Duchenne de Boulogne 463 105. Steinert's disease: dystrophia myotonica 469 106. Notes on tetanus: Hippocrates and Aretaeus 473 Miscellaneous 477 107. The Hippocratic oath 479 108. The caduceus and the Aesculapian staff 481 109. Galen of Pergamum: neurological notes 485 110. Walter Brown: early intravenous transfusion 493 111. Ammon's horn and the hippocampus 495 112 Clinical thermometers 497 113 Acromegaly (Pierre Marie's disease) 501 114 Who discovered insulin? 510 115 Who discovered aspirin? 513 116 Bromides in epilepsy 517 117 Harvey Cushing 524 118 Armand Trousseau, physician and neurologist 528 119 Ilya Ilyich Mechnikov and phagocytes 548 120 Sir James Paget 550 121 John and James Parkinson on appendicitis 556 122 The origins of syphilis 558 123 Charcot joints 563 124 Francis Bacon: father of the scientific experiment 566 125 Sir Charles Symonds 569 126 Derek Denny-Brown 573 Illnesses of the famous, and some medical truants 577 127. Peter Mark Roget and his thesaurus 579 128. Chekhov: playwright and physician 582 129. William Brownrigg: a doctor's adventures with physics 585 130. The emperor with the shaking head: Claudius' movement disorder 588 131. The madness of King George III 592 132. Johann Jakob Wepfer on cerebral haemorrhage, with a note on the apoplexy of Malpighi 597 133. Dr Samuel Johnson: a victim of Gilles de la Tourette's syndrome 602 134. Freud's migraine, and contributions to neurology 615 135. Wegener's granulomatosis 622Library of Congress Subject Headings for this publication: Neurology History, Neurology Anecdotes, Eponyms, Neurology history Anecdotes, Neurology history Collected Works, Eponyms Anecdotes, Eponyms Collected Works, Nervous System Diseases history Anecdotes, Nervous System Diseases history Collected Works