Moore R, Loveless M, Neufeld E, Yangco B, Frazier R, Carton G; International Conference on AIDS.

Int Conf AIDS. 1993 Jun 6-11; 9: 528 (abstract no. PO-B36-2355).

Univ. of Minn. Hospital.

OBJECTIVES: To identify the rationale for use of home parenteral nutrition (HPN) in HIV+ patients and the potential effects on patient outcome. METHODS: This is a nationwide, retrospective study of patients who received HPN through physicians in the Health Research Network within the last two years. Patient characteristics included an average age of 36.8 +/- 8.25 years, 94% male, 92% Caucasian, and 68% gay. Current vs usual weight ratio averaged 85 +/- 9%, with an average weight loss of 23 pounds over the previous 6 months. The most common reasons for starting HPN were nausea, vomiting, and anorexia. Two-thirds of the patients had opportunistic infections (O/Is). Quantitative assessment of gastrointestinal function was performed in one-third of the patients. Nutrition assessments were performed in two thirds of the patients. The average duration of therapy was 113 days, with a median duration of 85 days and a range of 4-515 days. RESULTS: Half of the patients showed a positive benefit to HPN as assessed by the physicians, with most patients gaining over 5 lbs and having a subjective improvement in their quality of life. Half the patients showed either no improvement or a decrease in the quality of life. The presence of an opportunistic infection did not predict response to HPN. CONCLUSIONS: Further investigation is needed to identify clinical characteristics and therapeutic guidelines associated with a positive response to HPN.

Publication Types:

• Meeting Abstracts

Keywords:

• Enteral Nutrition
• Home Nursing
• Hospitalization
• Humans
• Male
• Nutritional Status
• Parenteral Nutrition
• Parenteral Nutrition, Home
• Parenteral Nutrition, Total
• Retrospective Studies
• therapy

Other ID:

• 93335992

UI: 102205370

From Meeting Abstracts