1: HAS1 ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles [ Saccharomyces cerevisiae ]
GeneID: 855335 updated 08-Mar-2009 - Gene name
- HAS1
- Primary source
- SGD:S000004903
- Locus tag
- YMR290C
- Gene type
- protein coding
- RefSeq status
- Reviewed
- Organism
- Saccharomyces cerevisiae (strain: S288C)
- Lineage
- Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
- Also known as
- HAS1
[Top][Help]Genomic regions, transcripts, and products
Related Articles in PubMed
GeneRIFs: Gene References Into FunctionWhat's a GeneRIF?
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1. |
Mutational analysis of the conserved residues in motifs that are important for ATPase and unwinding activities of Has1p. |
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Has1p helicase is required for snoRNA release from pre-rRNA and production of the U6 snRNP |
[Top][Help]General gene informationGeneOntology Provided by SGD
[Top][Help]General protein information- Names
- ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
- Has1p
[Top][Help]NCBI Reference Sequences (RefSeq)Genome Annotation
The following sections contain reference sequences that belong to a specific genome build. Explain This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.
mRNA and Protein(s)
NP_014017.1 ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles; Has1p [Saccharomyces cerevisiae]
- UniProtKB/Swiss-Prot
- Q03532
- Conserved Domains (3) summary
- cd00268
Location:44–251
Blast Score:652
- DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif...
- cd00079
Location:287–377
Blast Score:235
- HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...
- COG0513
Location:14–500
Blast Score:830
- SrmB; Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]
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