Landry R, Cintron NM.
Aviat Space Environ Med. 1989 May; 60: 510.
Biomedical Laboratories Branch, KRUG International, Houston, TX, USA.
INTRODUCTION. The Space Station Health Maintenance Facility (HMF) will require a clinical hematology capability to monitor and diagnose the health status of crewmembers. Since conventional techniques present unique problems in a reduced-gravity environment, the Clay Adams QBC II Centrifugal Hematology System was evaluated for possible use in the HMF. METHODS. Hematocrit, platelet, total leukocytes, granulocyte and agranulocyte counts were measured. Blood samples were collected from 107 hospitalized patients (medical and surgical). Specimens were analyzed on the QBC II, a Coulter S Plus II, and Sysmex 5000 for comparison purposes. Manual differential counts were performed and centrifuged microhematocrits were measured. RESULTS. QBC hematocrit data were closer to the reference microhematocrit than the data from the Coulter and Sysmex. Total leukocyte and platelet counts from the QBC showed good correlation with both electronic methods. The QBC modified differential compared favorably with interlaboratory data when manual differential cell classes were appropriately combined. Non-separation of erythrocytes and granulocytes resulted in loss of leukocyte data with 8.4% of the specimens. CONCLUSION. The QBC II is easy to use and can provide reliable basic hematology data. Data are limited to hematocrit and platelet count in some specimens due to overlapping erythrocyte/leukocyte density.
Publication Types:
Keywords:
- Granulocytes
- Hematocrit
- Hematologic Tests
- Hematology
- Humans
- Leukocytes
- Platelet Count
- methods
- NASA Center JSC
- NASA Discipline Regulatory Physiology
Other ID:
UI: 102233982
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