US 7,402,558 B2
Method for aiding implantation or decreasing miscarriage rate
Yves Menezo, Clauire (France)
Assigned to Laboratoires Seronosa, Coinsins, Vaud (Switzerland)
Appl. No. 10/489,412
PCT Filed Sep. 12, 2002, PCT No. PCT/GB02/04167
§ 371(c)(1), (2), (4) Date Sep. 14, 2004,
PCT Pub. No. WO03/022303, PCT Pub. Date Mar. 20, 2003.
Claims priority of application No. 01307758 (EP), filed on Sep. 12, 2001.
Prior Publication US 2005/0020489 A1, Jan. 27, 2005
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/08 (2006.01); A61K 38/09 (2006.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 38/24 (2006.01); C07K 14/475 (2006.01)
U.S. Cl. 514—2  [514/8; 514/12; 514/15; 514/16; 424/85.1; 530/350; 530/351; 930/110; 930/130] 6 Claims
 
1. A method for aiding/encouraging implantation and/or decreasing miscarriage rates of an embryo in a human patient, comprising administering human luteinising hormone (hLH) during controlled ovarian hyperstimulation (COH) in a human patient in need thereof, while continuing administration of FSH, wherein the hLH is administered starting between the 3rd and 10th day after commencing treatment with FSH, to aid/encourage implantation and/or decrease miscarriage rates of an embryo in the human patient.