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hLF(1-11) Peptide and Fluconazole Act Synergistically against Systemic Infections with Fluconazole-Resistant Candida albicans.

LUPETTI A, BROUWER CP, WELLING MM, BOGAARDS S, DOGTEROM-BALLERING H, VAN DISSEL JT, NIBBERING PH; Interscience Conference on Antimicrobial Agents and Chemotherapy (43rd: 2003: Chicago, Ill.).

Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 2003 Sep 14-17; 43: abstract no. M-366.

Dept. of Infect. Dis., Leiden University Medical Center, Leiden, Netherlands.

BACKGROUND: In light of the need of new antifungal regimens we investigated whether the human lactoferrin-derived peptide hLF(1-11) is effective against infections with fluconazole-resistant Candida albicans and whether the combination of this peptide with fluconazole acts synergistically against such infections. METHODS: Fluconazole-resistant C. albicans (1 Publication Types:

  • Meeting Abstracts
Keywords:
  • Animals
  • Antifungal Agents
  • Antigens, Fungal
  • Candida albicans
  • Fluconazole
  • Humans
  • Lactoferrin
  • Mice
  • Peptides
  • immunology
Other ID:
  • GWAIDS0024909
UI: 102264533

From Meeting Abstracts




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