Supplementary material S2: List of gis, ordered by E2-domain family Each cluster of gi numbers represents a non-classical, eukaryotic E2 ligase domain variant and is preceded by a count of total members from selected lineages. Please refer to previous work for lists of prokaryotic E2 proteins (ftp://ftp.ncbi.nih.gov/pub/aravind/UB/). Each sequence is identified by gi, gene name, protein length, species name, lineage name, and genbank protein description. Note: eukaryotic proteomes with unassigned gi numbers have been assigned temporary ids, prefixed by species abbreviations which follow: Naegleria gruberi: Ngru Phytophthora sojae: Psoj Phytophthora ramorum: Pram Phaeodactylum tricornutum: Ptri Chlamydomonas reinhardtii: Crei Thalassiosira pseudonana: Tpseu Nematostella vectens: Nvec Branchiostoma floridae:Bflo --------------------------------------------------------------------- Table of Contents 1. Apg3 2. Apg10 3. Tsg101 (UEV) 4. BRUCE-like 5. UBE2W 6. Ufc1 7. Ubc6p 8. UbcI 9. AKTIP 10. RWD --------------------------------------------------------------------- 1. Apg3 **COUNTS** parabasalidea 1 heterolobosea 1 euglenozoa>kinetoplastida 4 alveolata 5 alveolata>ciliophora 6 stramenopiles 4 viridiplantae 3 entamoebidae 1 mycetozoa>dictyosteliida 2 fungi>ascomycota 10 fungi>basidiomycota 2 metazoa 1 metazoa>Choanoflagellida 1 metazoa>Chordata 4 metazoa>Cnidaria 1 metazoa>echinodermata 1 metazoa>hexapoda 4 metazoa>vertebrata 5 metazoa>vertebrata>actinopterygii 4 65303096 TA03605 203 Theileria annulata alveolata hypothetical protein, conserved [Theileria annulata]. X#46.m01688 X#46.m01688 389 Toxoplasma gondii alveolata autophagocytosis associated protein, putative 66359970 cgd8_2630 242 Cryptosporidium parvum Iowa II alveolata APG10/ Aut1p like like autophagocytosis protein involved in 71027271 TP03_0261 197 Theileria parva strain Muguga alveolata hypothetical protein TP03_0261 [Theileria parva strain Muguga]. 23613578 PFI0280c 298 Plasmodium falciparum 3D7 alveolata hypothetical protein [Plasmodium falciparum 3D7]. 124396640 GSPATT00032381001 229 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 89292028 TTHERM_01050620 280 Tetrahymena thermophila SB210 alveolata>ciliophora Autophagocytosis associated protein, C-terminal domain containing 124405511 GSPATT00000653001 240 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124430297 GSPATT00027413001 108 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124419471 GSPATT00018613001 241 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 89290045 TTHERM_00012980 225 Tetrahymena thermophila SB210 alveolata>ciliophora Autophagocytosis associated protein, C-terminal domain containing 56471771 46.t00033 268 Entamoeba histolytica HM-1:IMSS entamoebidae autophagocytosis protein, putative [Entamoeba histolytica 71421296 Tc00.1047053510257.90 270 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida autophagocytosis associated protein [Trypanosoma cruzi strain CL 68128829 LmjF33.0295 275 Leishmania major euglenozoa>kinetoplastida autophagocytosis protein, putative [Leishmania major]. 84043456 Tb927.2.1890 292 Trypanosoma brucei TREU927 euglenozoa>kinetoplastida autophagocytosis associated protein [Trypanosoma brucei TREU927]. 71649849 Tc00.1047053509213.130 270 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida autophagocytosis associated protein [Trypanosoma cruzi strain CL 50420719 DEHA0D10846g 324 Debaryomyces hansenii CBS767 fungi>ascomycota hypothetical protein DEHA0D10846g [Debaryomyces hansenii CBS767]. 50310697 KLLA0F06402g 302 Kluyveromyces lactis NRRL Y-1140 fungi>ascomycota unnamed protein product [Kluyveromyces lactis]. 50290141 CAGL0I05808g 309 Candida glabrata CBS 138 fungi>ascomycota hypothetical protein CAGL0I05808g [Candida glabrata CBS138]. 6324334 ATG3 310 Saccharomyces cerevisiae fungi>ascomycota Atg3p [Saccharomyces cerevisiae]. 42548126 FG08900.1 349 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG08900.1 [Gibberella zeae PH-1]. 85112065 NCU01955.1 352 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. 70998182 AFUA_5G08170 353 Aspergillus fumigatus Af293 fungi>ascomycota autophagocytosis protein Aut1, putative [Aspergillus fumigatus 50553884 YALI0E24453g 366 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 19113456 SPBC3B9.06c 275 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPBC3B9.06c [Schizosaccharomyces pombe 972h-]. 45198343 AGOS_AFL178W 282 Ashbya gossypii ATCC 10895 fungi>ascomycota AFL178Wp [Ashbya gossypii ATCC 10895]. 58260390 CNK00360 385 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota autophagy-related protein [Cryptococcus neoformans var. neoformans 71003271 UM00169.1 439 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM00169.1 [Ustilago maydis 521]. Ngru1000009601 Ngru1000009601 304 Naegleria gruberi heterolobosea fgeneshNG_pg.scaffold_40000109 17543646 Y55F3AM.4 305 Caenorhabditis elegans metazoa Y55F3AM.4 [Caenorhabditis elegans]. Mbre1000005126 Mbre1000005126 342 Monosiga brevicollis metazoa>Choanoflagellida fgenesh2_pg.scaffold_25000124 ci0100131803 ci0100131803 254 Ciona intestinalis metazoa>Chordata ci0100131803 Bflo1000027008 Bflo1000027008 1023 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pg.C_400088 Bflo1000029400 Bflo1000029400 318 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pg.C_1590012 ci0100142936 ci0100142936 312 Ciona intestinalis metazoa>Chordata ci0100146633 Nvec1000006208 Nvec1000006208 329 Nematostella vectensis metazoa>Cnidaria e_gw.31.166.1 115956521 LOC594526 268 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to MGC80121 protein [Strongylocentrotus 91092526 LOC655634 316 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG6877-PA [Tribolium castaneum]. 58379448 AgaP_ENSANGG00000012603 331 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000015092 [Anopheles gambiae str. PEST]. 66564768 LOC552315 327 Apis mellifera metazoa>hexapoda PREDICTED: similar to Aut1 CG6877-PA [Apis mellifera]. 21357935 Aut1 330 Drosophila melanogaster metazoa>hexapoda Aut1 CG6877-PA [Drosophila melanogaster]. 19526773 ATG3 314 Homo sapiens metazoa>vertebrata Apg3p [Homo sapiens]. 114588464 ATG3 318 Pan troglodytes metazoa>vertebrata PREDICTED: Apg3p isoform 2 [Pan troglodytes]. 19705511 Apg3l 314 Rattus norvegicus metazoa>vertebrata APG3 autophagy 3-like [Rattus norvegicus]. 114588462 ATG3 314 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein isoform 1 [Pan troglodytes]. 13385890 Atg3 314 Mus musculus metazoa>vertebrata autophagy Apg3p/Aut1p-like [Mus musculus]. 41053345 apg3l 317 Danio rerio metazoa>vertebrata>actinopterygii APG3 autophagy 3-like [Danio rerio]. 47226783 GSTEN:00027065:G:001 133 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47226782 GSTEN:00027064:G:001 135 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 68355530 LOC563944 66 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to APG3 autophagy 3-like [Danio rerio]. 66818030 DDBDRAFT_0217934 343 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0217934 [Dictyostelium discoideum 28828597 - 338 Dictyostelium discoideum mycetozoa>dictyosteliida hypothetical protein [Dictyostelium discoideum]. 121911929 TVAG_447140 258 Trichomonas vaginalis G3 parabasalidea autophagocytosis associated protein, putative [Trichomonas Tpseu1000007918 Tpseu1000007918 315 Thalassiosira pseudonana stramenopiles 145968 Psoj1000017156 Psoj1000017156 337 Phytophthora sojae stramenopiles 110627 Ptri1000002031 Ptri1000002031 303 Phaeodactylum tricornutum stramenopiles fgenesh1_pm.C_chr_1000016 Pram1000014227 Pram1000014227 323 Phytophthora ramorum stramenopiles 47287 18424474 AT5G61500 313 Arabidopsis thaliana viridiplantae autophagy 3 (APG3) [Arabidopsis thaliana]. Crei1000012355 Crei1000012355 307 Chlamydomonas reinhardtii viridiplantae estExt_fgenesh2_pg.C_50319 116058478 Ot06g04060 81 Ostreococcus tauri viridiplantae Protein involved in autophagocytosis during starvation (ISS) 2. Apg10 **COUNTS** parabasalidea 1 stramenopiles 2 viridiplantae 2 entamoebidae 1 mycetozoa>dictyosteliida 1 fungi>ascomycota 3 fungi>basidiomycota 1 metazoa 1 metazoa>Chordata 3 metazoa>Cnidaria 1 metazoa>hexapoda 3 metazoa>vertebrata 4 metazoa>vertebrata>actinopterygii 1 56467139 215.t00010 198 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 215.t00010 [Entamoeba histolytica HM-1:IMSS]. 19113870 SPAC227.04 179 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPAC227.04 [Schizosaccharomyces pombe 972h-]. 50425969 DEHA0G01309g 221 Debaryomyces hansenii CBS767 fungi>ascomycota hypothetical protein DEHA0G01309g [Debaryomyces hansenii CBS767]. 42544793 FG00611.1 313 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG00611.1 [Gibberella zeae PH-1]. 58267542 CNE03590 782 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hemolysin [Cryptococcus neoformans var. neoformans JEC21]. 71984851 D2085.2 157 Caenorhabditis elegans metazoa D2085.2 [Caenorhabditis elegans]. ci0100138026 ci0100138026 101 Ciona intestinalis metazoa>Chordata ci0100138026 Bflo1000011200 Bflo1000011200 218 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_138000045 Bflo1000028874 Bflo1000028874 241 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pg.C_1380027 Nvec1000017690 Nvec1000017690 218 Nematostella vectensis metazoa>Cnidaria fgenesh1_pg.scaffold_108000021 110761124 LOC726781 197 Apis mellifera metazoa>hexapoda PREDICTED: similar to autophagy-related 10-like [Apis mellifera]. 58378916 ENSANGG00000018063 135 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000020552 [Anopheles gambiae str. PEST]. 28573298 CG12821 130 Drosophila melanogaster metazoa>hexapoda CG12821-PA [Drosophila melanogaster]. 18594496 ATG10 220 Homo sapiens metazoa>vertebrata APG10 autophagy 10-like [Homo sapiens]. 55624036 LOC461768 220 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein [Pan troglodytes]. 109464245 LOC688555 214 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to autophagy-related 10-like [Rattus 27777646 Atg10 215 Mus musculus metazoa>vertebrata autophagy-related 10-like [Mus musculus]. 47207141 GSTEN:00005155:G:001 141 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 60475073 DDBDRAFT_0190076 230 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0190076 [Dictyostelium discoideum 121893860 TVAG_457890 145 Trichomonas vaginalis G3 parabasalidea hypothetical protein TVAG_457890 [Trichomonas vaginalis G3]. Psoj1000014309 Psoj1000014309 239 Phytophthora sojae stramenopiles 142106 Pram1000006756 Pram1000006756 186 Phytophthora ramorum stramenopiles 76873 30680336 AT3G07525 226 Arabidopsis thaliana viridiplantae autophagocytosis-associated family protein [Arabidopsis thaliana]. 30680332 AT3G07525 225 Arabidopsis thaliana viridiplantae autophagocytosis-associated family protein [Arabidopsis thaliana]. 3. Tsg101 (UEV) **COUNTS** parabasalidea 2 euglenozoa>kinetoplastida 13 alveolata 2 alveolata>ciliophora 3 stramenopiles 5 viridiplantae 5 entamoebidae 6 fungi>ascomycota 8 fungi>basidiomycota 2 metazoa 1 metazoa>Choanoflagellida 1 metazoa>Chordata 10 metazoa>Cnidaria 1 metazoa>echinodermata 1 metazoa>hexapoda 5 metazoa>vertebrata 14 metazoa>vertebrata>actinopterygii 12 mycetozoa>dictyosteliida 1 65305040 TA06765 294 Theileria annulata alveolata hypothetical protein, conserved [Theileria annulata]. 71033227 TP01_0734 309 Theileria parva strain Muguga alveolata hypothetical protein TP01_0734 [Theileria parva strain Muguga]. 124407857 GSPATT00009545001 444 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 89285001 TTHERM_01027520 512 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 124396952 GSPATT00005706001 410 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 67478665 46.t00043 434 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 46.t00043 [Entamoeba histolytica HM-1:IMSS]. 67466467 310.t00002 322 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 310.t00002 [Entamoeba histolytica HM-1:IMSS]. 67481843 15.t00074 250 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 15.t00074 [Entamoeba histolytica HM-1:IMSS]. 56468853 134.t00016 212 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 134.t00016 [Entamoeba histolytica HM-1:IMSS]. 56469948 96.t00001 111 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 96.t00001 [Entamoeba histolytica HM-1:IMSS]. 67466719 296.t00005 494 Entamoeba histolytica HM-1:IMSS entamoebidae hypothetical protein 296.t00005 [Entamoeba histolytica HM-1:IMSS]. 71651794 Tc00.1047053505025.144 309 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71408683 Tc00.1047053509031.6 295 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71413390 Tc00.1047053509971.80 293 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 70834758 Tb11.01.4703 241 Trypanosoma brucei euglenozoa>kinetoplastida hypothetical protein, conserved [Trypanosoma brucei]. 71666894 Tc00.1047053506459.235 247 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71666892 Tc00.1047053506459.195 247 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71419864 Tc00.1047053508869.75 293 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71656365 Tc00.1047053508871.105 247 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein Tc00.1047053508871.105 [Trypanosoma cruzi 71413135 Tc00.1047053509097.28 247 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71659407 Tc00.1047053504081.23 293 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71659181 Tc00.1047053510377.61 293 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71655155 Tc00.1047053506967.13 293 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71662378 Tc00.1047053510021.185 247 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein Tc00.1047053510021.185 [Trypanosoma cruzi 45184818 AGOS_AAL006C 445 Ashbya gossypii ATCC 10895 fungi>ascomycota AAL006Cp [Ashbya gossypii ATCC 10895]. 50556412 VPS23 378 Yarrowia lipolytica CLIB122 fungi>ascomycota YlVPS23 [Yarrowia lipolytica]. 50426875 DEHA0G12397g 496 Debaryomyces hansenii CBS767 fungi>ascomycota hypothetical protein DEHA0G12397g [Debaryomyces hansenii CBS767]. 42547092 FG02656.1 519 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG02656.1 [Gibberella zeae PH-1]. 85093619 NCU05753.1 580 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. 70998933 AFUA_3G14380 579 Aspergillus fumigatus Af293 fungi>ascomycota endosomal sorting complex protein TSG101, putative [Aspergillus 50289071 CAGL0H03927g 468 Candida glabrata CBS 138 fungi>ascomycota unnamed protein product [Candida glabrata]. 42759852 STP22 385 Saccharomyces cerevisiae fungi>ascomycota Component of the ESCRT-I complex, which is involved in 46098756 UM02831.1 1157 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM02831.1 [Ustilago maydis 521]. 58264686 CNC02240 550 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hypothetical protein [Cryptococcus neoformans var. neoformans 71982582 C09G12.9 425 Caenorhabditis elegans metazoa C09G12.9 [Caenorhabditis elegans]. Mbre1000007539 Mbre1000007539 1347 Monosiga brevicollis metazoa>Choanoflagellida estExt_fgenesh2_pg.C_300048 ci0100154542 ci0100154542 317 Ciona intestinalis metazoa>Chordata ci0100154542 Bflo1000012054 Bflo1000012054 484 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_152000021 ci0100154515 ci0100154515 419 Ciona intestinalis metazoa>Chordata ci0100154515 Bflo1000010581 Bflo1000010581 401 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_127000072 Bflo1000016007 Bflo1000016007 306 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_226000051 Bflo1000047714 Bflo1000047714 372 Branchiostoma floridae metazoa>Chordata estExt_gwp.C_290132 Bflo1000042242 Bflo1000042242 69 Branchiostoma floridae metazoa>Chordata e_gw.285.132.1 Bflo1000036388 Bflo1000036388 116 Branchiostoma floridae metazoa>Chordata gw.291.66.1 Bflo1000042438 Bflo1000042438 119 Branchiostoma floridae metazoa>Chordata e_gw.298.13.1 Bflo1000048372 Bflo1000048372 144 Branchiostoma floridae metazoa>Chordata estExt_gwp.C_2850128 Nvec1000024634 Nvec1000024634 432 Nematostella vectensis metazoa>Cnidaria estExt_fgenesh1_pg.C_1050038 115681892 LOC590965 108 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to Tumor susceptibility gene 101, partial 91086823 LOC662712 4316 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG6303-PA [Tribolium castaneum]. 17648053 TSG101 408 Drosophila melanogaster metazoa>hexapoda tumor suppressor protein 101 CG9712-PA [Drosophila melanogaster]. 66531777 LOC409438 416 Apis mellifera metazoa>hexapoda PREDICTED: similar to tumor suppressor protein 101 CG9712-PA [Apis 91080041 LOC661457 392 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG9712-PA [Tribolium castaneum]. 58388004 ENSANGG00000011072 376 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000013561 [Anopheles gambiae str. PEST]. 109458775 LOC691172 683 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2-like [Rattus 114636495 LOC748881 215 Pan troglodytes metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2-like isoform 23943814 UEV3 379 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2-like [Homo sapiens]. 114636489 LOC748881 379 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2-like isoform 7 [Pan 5454140 TSG101 390 Homo sapiens metazoa>vertebrata tumor susceptibility gene 101 [Homo sapiens]. 109461971 LOC688000 470 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2-like [Rattus 114636476 TSG101 390 Pan troglodytes metazoa>vertebrata PREDICTED: tumor susceptibility gene 101 isoform 1 [Pan 48374087 Tsg101 391 Rattus norvegicus metazoa>vertebrata tumor susceptibility gene 101 [Rattus norvegicus]. 11230780 Tsg101 391 Mus musculus metazoa>vertebrata tumor susceptibility gene 101 protein [Mus musculus]. 114636491 LOC748881 357 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2-like isoform 3 [Pan 114636478 TSG101 403 Pan troglodytes metazoa>vertebrata PREDICTED: tumor susceptibility gene 101 isoform 2 [Pan 70780379 Attp 250 Mus musculus metazoa>vertebrata signaling molecule ATTP [Mus musculus]. 114636483 LOC748881 449 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2-like isoform 6 [Pan 114636481 LOC748881 471 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2-like isoform 8 [Pan 68368272 LOC562443 816 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to FLJ10111 [Danio rerio]. 68356050 LOC567642 984 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to RING finger protein 31 (Zinc 68364140 LOC558584 396 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to tumor susceptibility gene 101 isoform 2 68405599 zgc:100959 471 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: zgc:100959 [Danio rerio]. 68364142 LOC558584 393 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to tumor susceptibility gene 101 isoform 1 47203297 GSTEN:00012595:G:001 192 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 50344832 zgc:86926 390 Danio rerio metazoa>vertebrata>actinopterygii hypothetical protein LOC415179 [Danio rerio]. 47215244 GSTEN:00019782:G:001 470 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 68405637 LOC561016 185 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to tumor susceptibility gene 101 [Danio rerio]. 47212486 GSTEN:00004508:G:001 463 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47217083 GSTEN:00021501:G:001 371 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 68405668 LOC564878 185 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to tumor susceptibility gene 101 [Danio rerio]. 66807691 DDBDRAFT_0218848 478 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0218848 [Dictyostelium discoideum 121907565 TVAG_128690 264 Trichomonas vaginalis G3 parabasalidea MGC81040 protein, putative [Trichomonas vaginalis G3]. 121915555 TVAG_193190 293 Trichomonas vaginalis G3 parabasalidea hypothetical protein TVAG_193190 [Trichomonas vaginalis G3]. Psoj1000006153 Psoj1000006153 412 Phytophthora sojae stramenopiles 132761 Ptri1000008763 Ptri1000008763 411 Phaeodactylum tricornutum stramenopiles estExt_Genewise1.C_chr_140041 Ptri1000004948 Ptri1000004948 421 Phaeodactylum tricornutum stramenopiles estExt_fgenesh1_pg.C_chr_230106 Pram1000004476 Pram1000004476 444 Phytophthora ramorum stramenopiles 79629 Tpseu1000001553 Tpseu1000001553 400 Thalassiosira pseudonana stramenopiles 103937 116056391 Ot03g00280 438 Ostreococcus tauri viridiplantae putative human tumor susceptibility gene-like protein (ISS) 18399596 ATELC/ELC 398 Arabidopsis thaliana viridiplantae ATELC/ELC; ubiquitin binding [Arabidopsis thaliana]. Crei1000005374 Crei1000005374 525 Chlamydomonas reinhardtii viridiplantae Chlre2_kg.scaffold_16000223 15240732 ATELC-LIKE/ELC-LIKE 368 Arabidopsis thaliana viridiplantae ATELC-LIKE/ELC-LIKE [Arabidopsis thaliana]. 42569747 AT2G38830 331 Arabidopsis thaliana viridiplantae tumor susceptibility protein-related [Arabidopsis thaliana]. 4. BRUCE-like **COUNTS** alveolata>ciliophora 12 fungi>ascomycota 3 fungi>basidiomycota 2 metazoa 1 metazoa>Chordata 7 metazoa>Cnidaria 5 metazoa>echinodermata 1 metazoa>hexapoda 8 metazoa>vertebrata 12 metazoa>vertebrata>actinopterygii 7 mycetozoa>dictyosteliida 2 stramenopiles 1 viridiplantae 6 124406526 GSPATT00008424001 4620 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124400960 GSPATT00035572001 2472 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 89285001 TTHERM_01027520 512 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 89289979 TTHERM_00011330 464 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 89299207 TTHERM_00481290 2633 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 89303321 TTHERM_00149190 6304 Tetrahymena thermophila SB210 alveolata>ciliophora ubiquitin-activating enzyme E1 family protein [Tetrahymena 124401200 GSPATT00035810001 5133 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124399658 GSPATT00034627001 2123 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 89288400 TTHERM_00028560 3915 Tetrahymena thermophila SB210 alveolata>ciliophora ubiquitin-activating enzyme E1 family protein [Tetrahymena 124409420 GSPATT00010919001 1850 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124398217 GSPATT00033569001 2396 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124412336 GSPATT00012991001 2601 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 85118516 NCU02688.1 440 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. 70999189 AFUA_3G13060 1062 Aspergillus fumigatus Af293 fungi>ascomycota ubiquitin conjugating enzyme, putative [Aspergillus fumigatus 42544747 FG01207.1 431 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG01207.1 [Gibberella zeae PH-1]. 58261412 CNL05830 927 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hypothetical protein [Cryptococcus neoformans var. neoformans 58268232 CNF01270 920 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hypothetical protein [Cryptococcus neoformans var. neoformans 71981623 ubc-17 679 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-17) [Caenorhabditis Bflo1000002074 Bflo1000002074 527 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_8000077 ci0100131458 ci0100131458 1058 Ciona intestinalis metazoa>Chordata ci0100131458 Bflo1000037265 Bflo1000037265 301 Branchiostoma floridae metazoa>Chordata e_gw.8.290.1 Bflo1000027761 Bflo1000027761 1307 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pg.C_760117 Bflo1000048584 Bflo1000048584 307 Branchiostoma floridae metazoa>Chordata estExt_gwp.C_3740030 Bflo1000011222 Bflo1000011222 981 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_138000092 Bflo1000025135 Bflo1000025135 307 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pm.C_2360005 Nvec1000007435 Nvec1000007435 158 Nematostella vectensis metazoa>Cnidaria e_gw.69.171.1 Nvec1000012274 Nvec1000012274 222 Nematostella vectensis metazoa>Cnidaria e_gw.2654.4.1 Nvec1000013121 Nvec1000013121 275 Nematostella vectensis metazoa>Cnidaria estExt_gwp.C_30788 Nvec1000015586 Nvec1000015586 1039 Nematostella vectensis metazoa>Cnidaria fgenesh1_pg.scaffold_10000074 Nvec1000005680 Nvec1000005680 659 Nematostella vectensis metazoa>Cnidaria e_gw.18.24.1 115964468 LOC580131 234 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: hypothetical protein [Strongylocentrotus purpuratus]. 91086823 LOC662712 4316 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG6303-PA [Tribolium castaneum]. 91084477 LOC659924 1041 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG10254-PA, isoform A [Tribolium castaneum]. 24649371 CG10254 1398 Drosophila melanogaster metazoa>hexapoda CG10254-PB, isoform B [Drosophila melanogaster]. 110760609 LOC724799 1287 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG10254-PA, isoform A [Apis mellifera]. 58383761 ENSANGG00000017845 1220 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000020334 [Anopheles gambiae str. PEST]. 45550729 Bruce 4876 Drosophila melanogaster metazoa>hexapoda Bruce CG6303-PA [Drosophila melanogaster]. 58382934 IAP6 4760 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000002826 [Anopheles gambiae str. PEST]. 110756922 LOC411115 4673 Apis mellifera metazoa>hexapoda PREDICTED: similar to Bruce CG6303-PA [Apis mellifera]. 61744456 BIRC6 4829 Homo sapiens metazoa>vertebrata baculoviral IAP repeat-containing 6 [Homo sapiens]. 114666526 LOC455196 371 Pan troglodytes metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2Z [Pan 31542455 Ube2z 350 Mus musculus metazoa>vertebrata ubiquitin-conjugating enzyme E2Z (putative) [Mus musculus]. 10048468 Birc6 4845 Mus musculus metazoa>vertebrata baculoviral IAP repeat-containing 6 [Mus musculus]. 109478992 Birc6_predicted 5017 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to baculoviral IAP repeat-containing 6 [Rattus 50234896 Ube2o 1288 Mus musculus metazoa>vertebrata ubiquitin-conjugating enzyme E2O [Mus musculus]. 33636750 UBE2O 1292 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2O [Homo sapiens]. 12751495 UBE2Z 246 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2Z (putative) [Homo sapiens]. 109492276 Ube2o_predicted 1312 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2O [Rattus 109489413 Ube2o_predicted 1315 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2O [Rattus 83320076 Ube2z 246 Rattus norvegicus metazoa>vertebrata ubiquitin-conjugating enzyme E2Z (putative) [Rattus norvegicus]. 114670605 UBE2O 1392 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2O [Pan troglodytes]. 47213169 GSTEN:00010000:G:001 2135 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 68387366 LOC566895 354 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to Baculoviral IAP repeat-containing protein 6 68437089 LOC564215 837 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to RIKEN cDNA B230113M03 [Danio rerio]. 50539720 zgc:92419 248 Danio rerio metazoa>vertebrata>actinopterygii hypothetical protein LOC436602 [Danio rerio]. 47213168 GSTEN:00009999:G:001 3047 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47214958 GSTEN:00032514:G:001 1309 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47217004 GSTEN:00020460:G:001 403 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 28830048 - 2208 Dictyostelium discoideum mycetozoa>dictyosteliida similar to Homo sapiens (Human). Hypothetical protein FLJ13786 (EC 60472388 DDBDRAFT_0217536 910 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0217536 [Dictyostelium discoideum Ptri1000008184 Ptri1000008184 415 Phaeodactylum tricornutum stramenopiles estExt_fgenesh1_pg.C_chr_190218 15219165 UBC26 1163 Arabidopsis thaliana viridiplantae UBC26 (ubiquitin-conjugating enzyme 25); ubiquitin-protein ligase Crei1000012890 Crei1000012890 222 Chlamydomonas reinhardtii viridiplantae estExt_fgenesh2_pg.C_110201 30685832 PHO2/UBC24 907 Arabidopsis thaliana viridiplantae PHO2/UBC24 (PHOSPHATE 2); ubiquitin-protein ligase [Arabidopsis 15227320 UBC23 1102 Arabidopsis thaliana viridiplantae UBC23 (ubiquitin-conjugating enzyme 22); ubiquitin-protein ligase 15229481 UBC25 609 Arabidopsis thaliana viridiplantae UBC25 (ubiquitin-conjugating enzyme 23); small conjugating protein 5. UBE2W **COUNTS** heterolobosea 1 alveolata 2 alveolata>ciliophora 5 viridiplantae 5 fungi>ascomycota 3 fungi>basidiomycota 1 metazoa 1 metazoa>Chordata 3 metazoa>Cnidaria 1 metazoa>echinodermata 1 metazoa>hexapoda 4 metazoa>vertebrata 7 metazoa>vertebrata>actinopterygii 3 mycetozoa>dictyosteliida 1 23509349 PF14_0128 299 Plasmodium falciparum 3D7 alveolata ubiquitin conjugating enzyme, putative [Plasmodium falciparum 3D7]. VIIb#55.m04812 VIIb#55.m04812 287 Toxoplasma gondii alveolata ubiquitin-conjugating enzyme domain-containing protein 89300310 TTHERM_00285290 256 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 94364832 Ube2w 180 Mus musculus metazoa>vertebrata PREDICTED: similar to CG7220-PA, isoform A isoform 5 [Mus 50557414 YALI0F31955g 178 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 82795563 Ube2w 178 Mus musculus metazoa>vertebrata PREDICTED: similar to CG7220-PA, isoform A isoform 11 [Mus 114620512 UBE2W 162 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2W (putative) isoform 1 47933381 UBE2W 162 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2W (putative) isoform 1 [Homo 18401461 ATUBC2-1 161 Arabidopsis thaliana viridiplantae ATUBC2-1 (Arabidopsis thaliana ubiquitin-conjugating enzyme); 18410856 UBC16 161 Arabidopsis thaliana viridiplantae UBC16 (ubiquitin-conjugating enzyme 15); ubiquitin-protein ligase 18419831 UBC17 161 Arabidopsis thaliana viridiplantae UBC17 (UBIQUITIN-CONJUGATING ENZYME 17); ubiquitin-protein ligase 18422281 UBC18 161 Arabidopsis thaliana viridiplantae UBC18 (ubiquitin-conjugating enzyme 16); ubiquitin-protein ligase Crei1000002793 Crei1000002793 161 Chlamydomonas reinhardtii viridiplantae e_gwW.24.158.1 46124999 FG06877.1 158 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG06877.1 [Gibberella zeae PH-1]. 71002042 AFUA_2G13690 157 Aspergillus fumigatus Af293 fungi>ascomycota ubiquitin conjugating enzyme, putative [Aspergillus fumigatus 28573347 CG7220 154 Drosophila melanogaster metazoa>hexapoda CG7220-PA, isoform A [Drosophila melanogaster]. 58387116 ENSANGG00000018586 154 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000024002 [Anopheles gambiae str. PEST]. 66549055 LOC409100 154 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG7220-PA, isoform A [Apis mellifera]. 91079008 LOC663661 154 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG7220-PA, isoform A [Tribolium castaneum]. 124416285 GSPATT00016175001 152 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 17510293 ubc-16 152 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-16) [Caenorhabditis 46099348 UM03443.1 152 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM03443.1 [Ustilago maydis 521]. Nvec1000014187 Nvec1000014187 153 Nematostella vectensis metazoa>Cnidaria estExt_gwp.C_3490026 114620514 UBE2W 151 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2W (putative) isoform 2 45387655 flj11011l 151 Danio rerio metazoa>vertebrata>actinopterygii hypothetical protein LOC402907 [Danio rerio]. 47933385 UBE2W 151 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2W (putative) isoform 2 [Homo Bflo1000025168 Bflo1000025168 152 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pm.C_2780002 124394210 GSPATT00030369001 150 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124397544 GSPATT00032900001 150 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 115663109 LOC582071 149 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to Ubiquitin-conjugating enzyme E2W (putative) 66827055 DDBDRAFT_0202295 149 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0202295 [Dictyostelium discoideum 124399351 GSPATT00034321001 148 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. Ngru1000001737 Ngru1000001737 148 Naegleria gruberi heterolobosea fgeneshHS_pm.scaffold_72000004 47223533 GSTEN:00015564:G:001 144 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. ci0100140113 ci0100140113 145 Ciona intestinalis metazoa>Chordata ci0100140113 Bflo1000032579 Bflo1000032579 144 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pg.C_5140030 68356096 LOC556071 126 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to CG7220-PB, isoform B [Danio rerio]. 109475992 LOC682704 396 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to CG7220-PA, isoform A [Rattus norvegicus]. 6. Ufc1 **COUNTS** heterolobosea 1 alveolata 3 alveolata>ciliophora 3 euglenozoa>kinetoplastida 3 metazoa 1 metazoa>Choanoflagellida 1 metazoa>Chordata 3 metazoa>Cnidaria 2 metazoa>echinodermata 2 metazoa>hexapoda 4 metazoa>vertebrata 6 metazoa>vertebrata>actinopterygii 1 mycetozoa>dictyosteliida 1 stramenopiles 1 viridiplantae 2 65305321 TA20810 162 Theileria annulata alveolata protein CGI-126, putative [Theileria annulata]. 71032621 TP01_0425 172 Theileria parva strain Muguga alveolata hypothetical protein TP01_0425 [Theileria parva strain Muguga]. V#31.m00087 V#31.m00087 158 Toxoplasma gondii alveolata hypothetical protein 124411671 GSPATT00012387001 156 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124416518 GSPATT00016381001 156 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 89284506 TTHERM_01108500 180 Tetrahymena thermophila SB210 alveolata>ciliophora hypothetical protein TTHERM_01108500 [Tetrahymena thermophila 68125492 LmjF15.1250 171 Leishmania major euglenozoa>kinetoplastida hypothetical protein, conserved [Leishmania major]. 71650234 Tc00.1047053506445.100 164 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein [Trypanosoma cruzi strain CL Brener]. 71744660 Tb09.160.4150 165 Trypanosoma brucei TREU927 euglenozoa>kinetoplastida hypothetical protein Tb09.160.4150 [Trypanosoma brucei TREU927]. Ngru1000001149 Ngru1000001149 176 Naegleria gruberi heterolobosea e_gw1.20.112.1 17552592 C40H1.6 162 Caenorhabditis elegans metazoa C40H1.6 [Caenorhabditis elegans]. Mbre1000002981 Mbre1000002981 167 Monosiga brevicollis metazoa>Choanoflagellida fgenesh2_pm.scaffold_3000061 ci0100146879 ci0100146879 166 Ciona intestinalis metazoa>Chordata ci0100146879 Bflo1000011222 Bflo1000011222 981 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_138000092 Bflo1000025213 Bflo1000025213 170 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pm.C_3610002 Nvec1000018661 Nvec1000018661 170 Nematostella vectensis metazoa>Cnidaria fgenesh1_pg.scaffold_199000025 Nvec1000012015 Nvec1000012015 116 Nematostella vectensis metazoa>Cnidaria e_gw.1650.2.1 72013071 LOC582152 139 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to conserved hypothetical protein 115937394 LOC582152 170 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to conserved hypothetical protein 58389907 ENSANGG00000008034 164 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000010523 [Anopheles gambiae str. PEST]. 66561255 LOC551106 170 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG8386-PA [Apis mellifera]. 19922352 CG8386 164 Drosophila melanogaster metazoa>hexapoda CG8386-PA [Drosophila melanogaster]. 91084695 LOC657656 166 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to Ufm1-conjugating enzyme 1 (Ubiquitin-fold 13384768 Ufc1 167 Mus musculus metazoa>vertebrata ubiquitin-fold modifier conjugating enzyme 1 [Mus musculus]. 114560786 LOC457449 122 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein isoform 1 [Pan troglodytes]. 7705481 UFC1 167 Homo sapiens metazoa>vertebrata ubiquitin-fold modifier conjugating enzyme 1 [Homo sapiens]. 55588606 LOC457449 167 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]. 114560788 LOC457449 148 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]. 51172600 Ufc1 167 Rattus norvegicus metazoa>vertebrata Ufm1-conjugating enzyme 1 [Rattus norvegicus]. 51011123 zgc:100800 166 Danio rerio metazoa>vertebrata>actinopterygii hypothetical protein LOC445256 [Danio rerio]. 90970505 ufc1 164 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida ubiquitin-like (UBL) post-translational modifier [Dictyostelium Pram1000015146 Pram1000015146 158 Phytophthora ramorum stramenopiles 53495 Crei1000013700 Crei1000013700 167 Chlamydomonas reinhardtii viridiplantae estExt_fgenesh2_pg.C_240032 18396376 AT1G27530 174 Arabidopsis thaliana viridiplantae unknown protein [Arabidopsis thaliana]. 7. Ubc6p **COUNTS** diplomonadida group>diplomonadida group 3 parabasalidea 2 euglenozoa>kinetoplastida 8 heterolobosea 2 alveolata 4 alveolata>ciliophora 6 stramenopiles 11 viridiplantae 8 entamoebidae 3 mycetozoa>dictyosteliida 3 fungi>ascomycota 14 fungi>basidiomycota 3 metazoa 3 metazoa>Choanoflagellida 3 metazoa>Chordata 4 metazoa>Cnidaria 3 metazoa>echinodermata 2 metazoa>hexapoda 6 metazoa>vertebrata 10 metazoa>vertebrata>actinopterygii 5 50554345 YALI0E30173g 132 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 50550481 YALI0D11748g 252 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 46101486 UM05955.1 223 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM05955.1 [Ustilago maydis 521]. 71423664 Tc00.1047053504055.81 225 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida ubiquitin-conjugating enzyme E2 [Trypanosoma cruzi strain CL 71655980 Tc00.1047053508387.100 437 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida ubiquitin-conjugating enzyme [Trypanosoma cruzi strain CL Brener]. 71668166 Tc00.1047053506435.300 225 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida ubiquitin-conjugating enzyme E2 [Trypanosoma cruzi strain CL 71665910 Tc00.1047053506789.200 410 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida ubiquitin-conjugating enzyme [Trypanosoma cruzi strain CL Brener]. 62359387 Tb927.4.3190 220 Trypanosoma brucei euglenozoa>kinetoplastida ubiquitin-conjugating enzyme E2, putative [Trypanosoma brucei]. 70802852 - 310 Trypanosoma brucei euglenozoa>kinetoplastida ubiquitin-conjugating enzyme, putative [Trypanosoma brucei]. 121894423 TVAG_091080 352 Trichomonas vaginalis G3 parabasalidea Ubiquitin-conjugating enzyme family protein [Trichomonas vaginalis 121911847 TVAG_066800 344 Trichomonas vaginalis G3 parabasalidea Ubiquitin-conjugating enzyme family protein [Trichomonas vaginalis 91082969 LOC662641 225 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to ubiquitin conjugating enzyme E2, J2 isoform 2 91079666 LOC655113 268 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to ubiquitin-conjugating enzyme E2, J1 Ib#25.m01819 Ib#25.m01819 676 Toxoplasma gondii alveolata hypothetical protein XII#65.m01972 XII#65.m01972 202 Toxoplasma gondii alveolata ubiquitin-conjugating enzyme E2, putative XII#50.m03405 XII#50.m03405 207 Toxoplasma gondii alveolata ubiquitin-conjugating enzyme E2, putative Tpseu1000010010 Tpseu1000010010 175 Thalassiosira pseudonana stramenopiles 160728 Tpseu1000002627 Tpseu1000002627 318 Thalassiosira pseudonana stramenopiles 109475 Tpseu1000004117 Tpseu1000004117 183 Thalassiosira pseudonana stramenopiles 119221 47212316 GSTEN:00003577:G:001 185 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47190747 GSTEN:00037077:G:001 81 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 89287327 TTHERM_00470910 443 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 89303616 TTHERM_00931940 221 Tetrahymena thermophila SB210 alveolata>ciliophora Ubiquitin-conjugating enzyme family protein [Tetrahymena 115969448 LOC590010 240 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to LOC495424 protein [Strongylocentrotus 72159165 LOC587822 370 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to ubiquitin-conjugating enzyme E2, J1 (UBC6 19114168 SPAC10F6.05c 227 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPAC10F6.05c [Schizosaccharomyces pombe 6320947 UBC6 250 Saccharomyces cerevisiae fungi>ascomycota Ubc6p [Saccharomyces cerevisiae]. 56090425 MGC94113 259 Rattus norvegicus metazoa>vertebrata similar to Ubc6p homolog [Rattus norvegicus]. 109474783 Ube2j1_predicted 386 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2, J1 [Rattus 109476293 Ube2j1_predicted 426 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2, J1 [Rattus Psoj1000015568 Psoj1000015568 249 Phytophthora sojae stramenopiles 143578 Psoj1000000332 Psoj1000000332 214 Phytophthora sojae stramenopiles 108600 Pram1000004878 Pram1000004878 332 Phytophthora ramorum stramenopiles 79160 Pram1000009034 Pram1000009034 185 Phytophthora ramorum stramenopiles 74102 Pram1000009035 Pram1000009035 225 Phytophthora ramorum stramenopiles 74101 Ptri1000008341 Ptri1000008341 119 Phaeodactylum tricornutum stramenopiles gw1.25.109.1 Ptri1000001394 Ptri1000001394 223 Phaeodactylum tricornutum stramenopiles fgenesh1_pg.C_chr_12000047 Ptri1000004266 Ptri1000004266 143 Phaeodactylum tricornutum stramenopiles e_gw1.10.176.1 124397229 GSPATT00032588001 322 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124408394 GSPATT00010030001 214 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124394906 GSPATT00005174001 232 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 124398877 GSPATT00033849001 388 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 114550572 LOC457188 267 Pan troglodytes metazoa>vertebrata PREDICTED: similar to ubiquitin conjugating enzyme 6 [Pan 114608464 UBE2J1 318 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2, J1 [Pan troglodytes]. 116058293 Ot06g02230 437 Ostreococcus tauri viridiplantae Non-Canonical UBiquitin Conjugating Enzyme 1 (ISS) [Ostreococcus 116054737 Ot14g00680 209 Ostreococcus tauri viridiplantae Ubiquitin-protein ligase (ISS) [Ostreococcus tauri]. 85099285 NCU01268.1 313 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. 85098002 NCU05592.1 232 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. Nvec1000011974 Nvec1000011974 81 Nematostella vectensis metazoa>Cnidaria e_gw.1577.2.1 Nvec1000008459 Nvec1000008459 129 Nematostella vectensis metazoa>Cnidaria e_gw.112.71.1 Nvec1000013828 Nvec1000013828 218 Nematostella vectensis metazoa>Cnidaria estExt_gwp.C_1190068 Ngru1000000443 Ngru1000000443 140 Naegleria gruberi heterolobosea gw1.2.320.1 Ngru1000015437 Ngru1000015437 209 Naegleria gruberi heterolobosea estExt_fgeneshNG_kg.C_40012 85662413 Ube2j2 271 Mus musculus metazoa>vertebrata ubiquitin-conjugating enzyme E2, J2 homolog isoform a [Mus 31980960 Ube2j1 318 Mus musculus metazoa>vertebrata ubiquitin-conjugating enzyme E2, J1 [Mus musculus]. Mbre1000001520 Mbre1000001520 3469 Monosiga brevicollis metazoa>Choanoflagellida fgenesh1_pg.scaffold_23000057 Mbre1000003059 Mbre1000003059 227 Monosiga brevicollis metazoa>Choanoflagellida fgenesh2_pg.scaffold_2000117 Mbre1000002602 Mbre1000002602 111 Monosiga brevicollis metazoa>Choanoflagellida e_gw1.7.295.1 68223781 LmjF05.0930 464 Leishmania major euglenozoa>kinetoplastida ubiquitin-conjugating enzyme, putative [Leishmania major]. 68129257 LmjF34.0900 289 Leishmania major euglenozoa>kinetoplastida ubiquitin-conjugating enzyme E2, putative [Leishmania major]. 50309721 KLLA0E20493g 251 Kluyveromyces lactis NRRL Y-1140 fungi>ascomycota unnamed protein product [Kluyveromyces lactis]. 37577122 UBE2J1 318 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2, J1 [Homo sapiens]. 37577126 UBE2J2 275 Homo sapiens metazoa>vertebrata ubiquitin conjugating enzyme E2, J2 isoform 1 [Homo sapiens]. 37577124 UBE2J2 259 Homo sapiens metazoa>vertebrata ubiquitin conjugating enzyme E2, J2 isoform 2 [Homo sapiens]. 46127873 FG08314.1 264 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG08314.1 [Gibberella zeae PH-1]. 42554638 FG07464.1 328 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG07464.1 [Gibberella zeae PH-1]. 29251108 - 177 Giardia lamblia ATCC 50803 diplomonadida group>diplomonadida group GLP_487_28716_29249 [Giardia lamblia ATCC 50803]. 29250521 - 324 Giardia lamblia ATCC 50803 diplomonadida group>diplomonadida group GLP_68_18546_19520 [Giardia lamblia ATCC 50803]. 71078496 GLP_546_71955_72440 161 Giardia lamblia ATCC 50803 diplomonadida group>diplomonadida group ubquitin conjugating enzyme [Giardia lamblia ATCC 50803]. 67480959 22.t00035 145 Entamoeba histolytica HM-1:IMSS entamoebidae ubiquitin-conjugating enzyme [Entamoeba histolytica HM-1:IMSS]. 56472977 22.t00037 159 Entamoeba histolytica HM-1:IMSS entamoebidae ubiquitin-conjugating enzyme, putative [Entamoeba histolytica 67483836 4.t00050 344 Entamoeba histolytica HM-1:IMSS entamoebidae ubiquitin-conjugating enzyme [Entamoeba histolytica HM-1:IMSS]. 21358599 CG5823 283 Drosophila melanogaster metazoa>hexapoda CG5823-PA [Drosophila melanogaster]. 60462031 DDBDRAFT_0229815 170 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0229815 [Dictyostelium discoideum 60466117 DDBDRAFT_0218828 241 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0218828 [Dictyostelium discoideum 66813106 DDBDRAFT_0218298 401 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0218298 [Dictyostelium discoideum 50408085 DEHA0A09999g 242 Debaryomyces hansenii CBS767 fungi>ascomycota hypothetical protein DEHA0A09999g [Debaryomyces hansenii CBS767]. 50421749 DEHA0E02871g 296 Debaryomyces hansenii CBS767 fungi>ascomycota hypothetical protein DEHA0E02871g [Debaryomyces hansenii CBS767]. 68442601 LOC563187 259 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to LOC495424 protein isoform 1 [Danio rerio]. 68442599 LOC563187 185 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to Ubiquitin-conjugating enzyme E2 J2 68393616 LOC554884 314 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: hypothetical protein XP_697630 [Danio rerio]. 46228870 cgd8_3850 368 Cryptosporidium parvum Iowa II alveolata Ubc6p like ubiquiting conjugating enzyme E2, possible transmembrane 58268762 CNF02130 162 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota ubiquitin-conjugating enzyme E2-28.4KD [Cryptococcus neoformans 58267460 CNE03270 297 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota ubiquitin conjugating enzyme [Cryptococcus neoformans var. ci0100148642 ci0100148642 293 Ciona intestinalis metazoa>Chordata ci0100148642 ci0100138685 ci0100138685 233 Ciona intestinalis metazoa>Chordata ci0100138685 Crei1000003831 Crei1000003831 167 Chlamydomonas reinhardtii viridiplantae estExt_gwp_1H.C_640021 Crei1000011977 Crei1000011977 179 Chlamydomonas reinhardtii viridiplantae estExt_fgenesh2_kg.C_470012 50290111 CAGL0I05478g 246 Candida glabrata CBS 138 fungi>ascomycota hypothetical protein CAGL0I05478g [Candida glabrata CBS138]. 17532649 ubc-6 314 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-6) [Caenorhabditis 17537739 ubc-15 218 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-15) [Caenorhabditis 32563946 ubc-26 203 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-26) [Caenorhabditis Bflo1000025151 Bflo1000025151 240 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pm.C_5590003 Bflo1000029101 Bflo1000029101 275 Branchiostoma floridae metazoa>Chordata estExt_fgenesh2_pg.C_1470011 71002606 AFUA_2G16470 312 Aspergillus fumigatus Af293 fungi>ascomycota ubiquitin conjugating enzyme (UbcF), putative [Aspergillus 45201468 AGOS_AGR372W 242 Ashbya gossypii ATCC 10895 fungi>ascomycota AGR372Wp [Ashbya gossypii ATCC 10895]. 15240671 UBC33 243 Arabidopsis thaliana viridiplantae UBC33; ubiquitin-protein ligase [Arabidopsis thaliana]. 15220062 UBC34 237 Arabidopsis thaliana viridiplantae UBC34 (ubiquitin-conjugating enzyme 32); ubiquitin-protein ligase 18401338 UBC32 309 Arabidopsis thaliana viridiplantae UBC32 (ubiquitin-conjugating enzyme 31); ubiquitin-protein ligase 79330462 UBC33 230 Arabidopsis thaliana viridiplantae UBC33; ubiquitin-protein ligase [Arabidopsis thaliana]. 48132665 LOC413253 230 Apis mellifera metazoa>hexapoda PREDICTED: similar to Ubiquitin-conjugating enzyme E2 J2 66507431 LOC409794 265 Apis mellifera metazoa>hexapoda PREDICTED: similar to ubiquitin-conjugating enzyme E2, J1 [Apis 58388043 ENSANGG00000008285 127 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000010774 [Anopheles gambiae str. PEST]. 8. UbcI **COUNTS** parabasalidea 3 heterolobosea 2 stramenopiles 2 viridiplantae 2 fungi>ascomycota 2 metazoa 1 metazoa>Choanoflagellida 1 metazoa>Chordata 7 metazoa>Cnidaria 2 metazoa>echinodermata 2 metazoa>hexapoda 7 metazoa>vertebrata 22 metazoa>vertebrata>actinopterygii 4 94395457 3110006E14Rik 296 Mus musculus metazoa>vertebrata PREDICTED: similar to CG4502-PA, isoform A [Mus musculus]. 94408620 LOC245350 372 Mus musculus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2Q (putative) 2 94387187 Ube2q2 364 Mus musculus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2Q 2 [Mus 30725841 Ube2q2 378 Mus musculus metazoa>vertebrata ubiquitin-conjugating enzyme E2Q 2 [Mus musculus]. 51830637 LOC245350 387 Mus musculus metazoa>vertebrata PREDICTED: similar to Ubiquitin-conjugating enzyme E2Q (putative) 2 94396224 3110006E14Rik 304 Mus musculus metazoa>vertebrata PREDICTED: similar to CG4502-PA, isoform A [Mus musculus]. 30425296 E330021D16Rik 371 Mus musculus metazoa>vertebrata hypothetical protein LOC243676 [Mus musculus]. 31541872 Ube2q1 422 Mus musculus metazoa>vertebrata ubiquitin-conjugating enzyme E2Q [Mus musculus]. 115923264 LOC581772 341 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to GA15522-PA [Strongylocentrotus purpuratus]. 115966376 LOC591210 448 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: hypothetical protein [Strongylocentrotus purpuratus]. 116058204 Ot06g01340 200 Ostreococcus tauri viridiplantae Predicted ubiquitin-conjugating enzyme (ISS) [Ostreococcus tauri]. 70993182 AFUA_4G13940 1158 Aspergillus fumigatus Af293 fungi>ascomycota ubiquitin conjugating enzyme, putative [Aspergillus fumigatus 24639327 CG2924 397 Drosophila melanogaster metazoa>hexapoda CG2924-PA, isoform A [Drosophila melanogaster]. 19920874 CG4502 306 Drosophila melanogaster metazoa>hexapoda CG4502-PA, isoform A [Drosophila melanogaster]. 121908902 TVAG_467860 237 Trichomonas vaginalis G3 parabasalidea Ubiquitin-conjugating enzyme family protein [Trichomonas vaginalis 121900284 TVAG_153580 238 Trichomonas vaginalis G3 parabasalidea hypothetical protein TVAG_153580 [Trichomonas vaginalis G3]. 121908958 TVAG_043860 234 Trichomonas vaginalis G3 parabasalidea Ubiquitin-conjugating enzyme family protein [Trichomonas vaginalis 91082929 LOC661636 247 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG4502-PA, isoform A [Tribolium castaneum]. Bflo1000000060 Bflo1000000060 354 Branchiostoma floridae metazoa>Chordata fgenesh2_pm.scaffold_6000039 Bflo1000009658 Bflo1000009658 276 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_113000037 Bflo1000000133 Bflo1000000133 161 Branchiostoma floridae metazoa>Chordata fgenesh2_pm.scaffold_19000016 Bflo1000013501 Bflo1000013501 345 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_177000006 Bflo1000003589 Bflo1000003589 207 Branchiostoma floridae metazoa>Chordata fgenesh2_pg.scaffold_19000068 48104639 LOC412360 261 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG4502-PA, isoform A [Apis mellifera]. 48109570 LOC409607 382 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG2924-PC, isoform C [Apis mellifera]. Mbre1000002317 Mbre1000002317 171 Monosiga brevicollis metazoa>Choanoflagellida e_gw1.3.520.1 113416990 FLJ25076 245 Homo sapiens metazoa>vertebrata PREDICTED: similar to CG4502-PA, isoform A [Homo sapiens]. 31543906 UBE2Q1 422 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2Q [Homo sapiens]. 29789401 UBE2Q2 375 Homo sapiens metazoa>vertebrata ubiquitin-conjugating enzyme E2Q (putative) 2 [Homo sapiens]. 88982452 FLJ25076 283 Homo sapiens metazoa>vertebrata PREDICTED: similar to CG4502-PA, isoform A [Homo sapiens]. 58386327 ENSANGG00000010568 317 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000013057 [Anopheles gambiae str. PEST]. 58396115 ENSANGG00000009070 389 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000011559 [Anopheles gambiae str. PEST]. ci0100153655 ci0100153655 373 Ciona intestinalis metazoa>Chordata ci0100153655 ci0100140471 ci0100140471 313 Ciona intestinalis metazoa>Chordata ci0100140471 42551042 FG10841.1 1077 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG10841.1 [Gibberella zeae PH-1]. Crei1000012978 Crei1000012978 518 Chlamydomonas reinhardtii viridiplantae estExt_fgenesh2_pg.C_120266 Tpseu1000003290 Tpseu1000003290 162 Thalassiosira pseudonana stramenopiles 113635 Ptri1000000857 Ptri1000000857 518 Phaeodactylum tricornutum stramenopiles estExt_fgenesh1_pg.C_chr_180019 47229506 GSTEN:00017587:G:001 278 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47216182 GSTEN:00022489:G:001 297 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 47220542 GSTEN:00025628:G:001 417 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. Nvec1000021943 Nvec1000021943 159 Nematostella vectensis metazoa>Cnidaria fgenesh1_pm.scaffold_160000004 Nvec1000009989 Nvec1000009989 373 Nematostella vectensis metazoa>Cnidaria e_gw.227.7.1 109504540 LOC679949 264 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to CG4502-PA, isoform A [Rattus norvegicus]. 109465090 Ube2q_predicted 583 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2Q [Rattus 109484735 Ube2q2_predicted 597 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2Q 2 [Rattus 109510440 RGD1563226_predicted 492 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to ubiquitin-conjugating enzyme E2Q (putative) 2 68392303 LOC557472 279 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to CG4502-PA, isoform A [Danio rerio]. 114598936 LOC750981 291 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein [Pan troglodytes]. 114658247 UBE2Q2 375 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2Q (putative) 2 isoform 4 114658255 UBE2Q2 357 Pan troglodytes metazoa>vertebrata PREDICTED: similar to Ubiquitin-conjugating enzyme E2Q (putative) 2 114658251 UBE2Q2 353 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2Q (putative) 2 isoform 1 114658249 UBE2Q2 340 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein isoform 5 [Pan troglodytes]. 114559985 UBE2Q1 422 Pan troglodytes metazoa>vertebrata PREDICTED: ubiquitin-conjugating enzyme E2Q [Pan troglodytes]. 71984336 ubc-25 387 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-25) [Caenorhabditis Ngru1000014952 Ngru1000014952 330 Naegleria gruberi heterolobosea estExt_fgeneshNG_pg.C_610113 Ngru1000013764 Ngru1000013764 772 Naegleria gruberi heterolobosea estExt_fgeneshNG_pg.C_160052 9. AKTIP **COUNTS** parabasalidea 1 alveolata 2 alveolata>ciliophora 1 stramenopiles 3 fungi>basidiomycota 2 mycetozoa>dictyosteliida 1 metazoa 1 metazoa>Choanoflagellida 1 metazoa>Chordata 1 metazoa>Cnidaria 3 metazoa>echinodermata 1 metazoa>hexapoda 5 metazoa>vertebrata 7 metazoa>vertebrata>actinopterygii 2 121917901 TVAG_476010 182 Trichomonas vaginalis G3 parabasalidea Ubiquitin-conjugating enzyme family protein [Trichomonas vaginalis 23509112 PFL2100w 465 Plasmodium falciparum 3D7 alveolata hypothetical protein PFL2100w [Plasmodium falciparum 3D7]. Mbre1000000752 Mbre1000000752 386 Monosiga brevicollis metazoa>Choanoflagellida fgenesh1_pg.scaffold_7000053 114662500 FTS 332 Pan troglodytes metazoa>vertebrata PREDICTED: fused toes homolog isoform 5 [Pan troglodytes]. VIIb#55.m05100 VIIb#55.m05100 303 Toxoplasma gondii alveolata ubiquitin-conjugating enzyme domain-containing protein Nvec1000022094 Nvec1000022094 298 Nematostella vectensis metazoa>Cnidaria fgsh_est.C_scaffold_25000015 114662502 FTS 293 Pan troglodytes metazoa>vertebrata PREDICTED: fused toes homolog isoform 1 [Pan troglodytes]. 17566194 ubc-19 292 Caenorhabditis elegans metazoa UBiquitin Conjugating enzyme family member (ubc-19) [Caenorhabditis 58865430 Fts 292 Rattus norvegicus metazoa>vertebrata AKT interacting protein [Rattus norvegicus]. 61743933 AKTIP 292 Homo sapiens metazoa>vertebrata AKT interacting protein [Homo sapiens]. 6753918 Aktip 292 Mus musculus metazoa>vertebrata AKT interacting protein [Mus musculus]. 47216620 GSTEN:00025428:G:001 290 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 114600887 LOC736031 281 Pan troglodytes metazoa>vertebrata PREDICTED: similar to fused toes homolog [Pan troglodytes]. Pram1000008760 Pram1000008760 281 Phytophthora ramorum stramenopiles 74424 115929982 LOC578956 277 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: hypothetical protein [Strongylocentrotus purpuratus]. Nvec1000020327 Nvec1000020327 273 Nematostella vectensis metazoa>Cnidaria fgenesh1_pg.scaffold_1565000002 Nvec1000015413 Nvec1000015413 272 Nematostella vectensis metazoa>Cnidaria fgenesh1_pg.scaffold_6000043 91084089 LOC656942 267 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to fused toes (predicted) [Tribolium 24656026 CG16894 266 Drosophila melanogaster metazoa>hexapoda CG16894-PA [Drosophila melanogaster]. 66510005 LOC552831 266 Apis mellifera metazoa>hexapoda PREDICTED: similar to fused toes [Apis mellifera]. Bflo1000043060 Bflo1000043060 264 Branchiostoma floridae metazoa>Chordata e_gw.431.37.1 41056191 aktip 261 Danio rerio metazoa>vertebrata>actinopterygii akt interacting protein [Danio rerio]. Ptri1000004528 Ptri1000004528 250 Phaeodactylum tricornutum stramenopiles fgenesh1_pg.C_chr_3000244 17933724 cbx 244 Drosophila melanogaster metazoa>hexapoda crossbronx CG10536-PB, isoform B [Drosophila melanogaster]. 58258487 CNA02640 242 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hypothetical protein [Cryptococcus neoformans var. neoformans 71003864 UM00451.1 240 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM00451.1 [Ustilago maydis 521]. 124429462 GSPATT00026577001 239 Paramecium tetraurelia alveolata>ciliophora unnamed protein product [Paramecium tetraurelia]. 114662514 FTS 237 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein isoform 6 [Pan troglodytes]. 66816191 DDBDRAFT_0204404 232 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0204404 [Dictyostelium discoideum 58381786 ENSANGG00000011255 203 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000013744 [Anopheles gambiae str. PEST]. Tpseu1000010538 Tpseu1000010538 161 Thalassiosira pseudonana stramenopiles 165255 10.RWD **COUNTS** euglenozoa>kinetoplastida 4 heterolobosea 2 stramenopiles 8 alveolata 2 viridiplantae 14 fungi>ascomycota 31 fungi>basidiomycota 6 metazoa 6 metazoa>choanoflagellida 4 metazoa>chordata 28 metazoa>echinodermata 7 metazoa>hexapoda 21 metazoa>mollusca 9 metazoa>nematoda 7 metazoa>vertebrata 45 metazoa>vertebrata>actinopterygii 17 mycetozoa>dictyosteliida 5 28828088 - 2388 Dictyostelium discoideum mycetozoa>dictyosteliida similar to Derepression of GCN4 expression; Gcn2p [Saccharomyces 46100672 UM05045.1 1859 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM05045.1 [Ustilago maydis 521]. 42733778 - 1700 Dictyostelium discoideum mycetozoa>dictyosteliida similar to Derepression of GCN4 expression; Gcn2p [Saccharomyces 45184741 AGOS_AAL083W 1698 Ashbya gossypii ATCC 10895 fungi>ascomycota AAL083Wp [Ashbya gossypii ATCC 10895]. 46121513 FG05135.1 1698 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG05135.1 [Gibberella zeae PH-1]. 17537697 Y81G3A.3 1696 Caenorhabditis elegans metazoa>nematoda Y81G3A.3 [Caenorhabditis elegans]. 47230269 GSTEN:00032391:G:001 1683 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 116060479 Ot11g02100 1680 Ostreococcus tauri viridiplantae mRNA splicing factor ATP-dependent RNA helicase (ISS) [Ostreococcus 50305443 KLLA0C10802g 1672 Kluyveromyces lactis NRRL Y-1140 fungi>ascomycota unnamed protein product [Kluyveromyces lactis]. 6320489 GCN2 1659 Saccharomyces cerevisiae fungi>ascomycota Gcn2p [Saccharomyces cerevisiae]. 114656304 EIF2AK4 1649 Pan troglodytes metazoa>vertebrata PREDICTED: eukaryotic translation initiation factor 2 alpha kinase 62645579 Eif2ak4_predicted 1649 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to Eukaryotic translation initiation factor 65287717 EIF2AK4 1649 Homo sapiens metazoa>vertebrata eukaryotic translation initiation factor 2 alpha kinase 4 [Homo 50288841 CAGL0H01199g 1648 Candida glabrata CBS 138 fungi>ascomycota unnamed protein product [Candida glabrata]. 7305017 Eif2ak4 1648 Mus musculus metazoa>vertebrata eukaryotic translation initiation factor 2 alpha kinase 4 [Mus 85103595 NCU01187.1 1646 Neurospora crassa OR74A fungi>ascomycota hypothetical protein ( (X91867) CPC3 protein [Neurospora crassa 114656306 EIF2AK4 1621 Pan troglodytes metazoa>vertebrata PREDICTED: eukaryotic translation initiation factor 2 alpha kinase 114656310 EIF2AK4 1611 Pan troglodytes metazoa>vertebrata PREDICTED: eukaryotic translation initiation factor 2 alpha kinase 50546875 YALI0B14949g 1609 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 115954900 LOC579979 1605 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to Eukaryotic translation initiation factor 114656308 EIF2AK4 1592 Pan troglodytes metazoa>vertebrata PREDICTED: similar to GCN2beta isoform 2 [Pan troglodytes]. 70998472 AFUA_5G06750 1592 Aspergillus fumigatus Af293 fungi>ascomycota protein kinase (Gcn2), putative [Aspergillus fumigatus Af293]. 17137328 Gcn2 1589 Drosophila melanogaster metazoa>hexapoda Gcn2 CG1609-PA [Drosophila melanogaster]. 58393600 ENSANGG00000008705 1588 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000011194 [Anopheles gambiae str. PEST]. 63054755 SPBC36B7.09 1576 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPBC36B7.09 [Schizosaccharomyces pombe 972h-]. Bflo1000005297 Bflo1000005297 1539 Branchiostoma floridae metazoa>chordata fgenesh2_pg.scaffold_35000183 Bflo1000010868 Bflo1000010868 1531 Branchiostoma floridae metazoa>chordata fgenesh2_pg.scaffold_132000061 115746620 LOC588023 1517 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to Eukaryotic translation initiation factor Pram1000005575 Pram1000005575 1515 Phytophthora ramorum stramenopiles 78300 Psoj1000006922 Psoj1000006922 1508 Phytophthora sojae stramenopiles 133639 66827481 DDBDRAFT_0189340 1451 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0189340 [Dictyostelium discoideum 58262126 CNM01750 1447 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hypothetical protein CNM01750 [Cryptococcus neoformans var. 6323451 YLR419W 1435 Saccharomyces cerevisiae fungi>ascomycota Putative helicase with limited sequence similarity to human Rb 50290941 CAGL0J04532g 1420 Candida glabrata CBS 138 fungi>ascomycota unnamed protein product [Candida glabrata]. Mbre1000006681 Mbre1000006681 1419 Monosiga brevicollis metazoa>choanoflagellida estExt_fgenesh2_pg.C_110114 50423967 DEHA0F05170g 1408 Debaryomyces hansenii CBS767 fungi>ascomycota hypothetical protein DEHA0F05170g [Debaryomyces hansenii CBS767]. 50306461 KLLA0D03058g 1401 Kluyveromyces lactis NRRL Y-1140 fungi>ascomycota unnamed protein product [Kluyveromyces lactis]. 45190700 AGOS_AER094C 1398 Ashbya gossypii ATCC 10895 fungi>ascomycota AER094Cp [Ashbya gossypii ATCC 10895]. 71002536 AFUA_2G16140 1344 Aspergillus fumigatus Af293 fungi>ascomycota DEAD/DEAH box helicase, putative [Aspergillus fumigatus Af293]. 30694992 AT3G59410 1241 Arabidopsis thaliana viridiplantae protein kinase family protein [Arabidopsis thaliana]. 68128710 LmjF32.3110 962 Leishmania major euglenozoa>kinetoplastida hypothetical protein, conserved [Leishmania major]. Bflo1000014871 Bflo1000014871 693 Branchiostoma floridae metazoa>chordata fgenesh2_pg.scaffold_202000012 15223171 NHL8 688 Arabidopsis thaliana viridiplantae NHL8 (NDR1/HIN1-like 8); protein binding / zinc ion binding Pram1000007906 Pram1000007906 662 Phytophthora ramorum stramenopiles 75495 66826425 DDBDRAFT_0190829 588 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0190829 [Dictyostelium discoideum 58265564 CNC02490 548 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota regulation of translational termination-related protein 114602433 RNF14 526 Pan troglodytes metazoa>vertebrata PREDICTED: ring finger protein 14 isoform 8 [Pan troglodytes]. 41056245 zgc:66260 513 Danio rerio metazoa>vertebrata>actinopterygii hypothetical protein LOC100003846 [Danio rerio]. 72007037 LOC580319 505 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to androgen receptor associated protein 54 116061570 Ot02g04130 498 Ostreococcus tauri viridiplantae zinc finger (ISS) [Ostreococcus tauri]. 68392563 LOC558876 498 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to Ring finger protein 14 [Danio rerio]. 9910592 Rnf14 485 Mus musculus metazoa>vertebrata ring finger protein 14 [Mus musculus]. 110767586 LOC552305 484 Apis mellifera metazoa>hexapoda PREDICTED: similar to RING finger protein 14 (Androgen 109507232 Rnf14 479 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to RING finger protein 14 (Androgen 47219245 GSTEN:00033761:G:001 479 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 34577098 RNF14 474 Homo sapiens metazoa>vertebrata ring finger protein 14 isoform 1 [Homo sapiens]. 114583341 RNF25 459 Pan troglodytes metazoa>vertebrata PREDICTED: ring finger protein 25 isoform 2 [Pan troglodytes]. 34878787 RNF25 459 Homo sapiens metazoa>vertebrata ring finger protein 25 [Homo sapiens]. 50344828 rnf14 459 Danio rerio metazoa>vertebrata>actinopterygii ring finger protein 14 [Danio rerio]. 156226211 NEMVEDRAFT_v1g160848 457 Nematostella vectensis metazoa predicted protein [Nematostella vectensis]. 10946616 Rnf25 456 Mus musculus metazoa>vertebrata ring finger protein 25 [Mus musculus]. ci0100144226 ci0100144226 456 Ciona intestinalis metazoa>chordata ci0100144226 Bflo1000001057 Bflo1000001057 454 Branchiostoma floridae metazoa>chordata fgenesh2_pm.scaffold_858000004 17553680 F56D2.2 451 Caenorhabditis elegans metazoa>nematoda F56D2.2 [Caenorhabditis elegans]. 71009474 UM02130.1 445 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM02130.1 [Ustilago maydis 521]. 50549189 YALI0C20889g 440 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 17553686 F56D2.5 437 Caenorhabditis elegans metazoa>nematoda F56D2.5 [Caenorhabditis elegans]. 114672738 LOC455343 435 Pan troglodytes metazoa>vertebrata PREDICTED: similar to IMPACT [Pan troglodytes]. 19114414 SPAC1002.14 435 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPAC1002.14 [Schizosaccharomyces pombe 972h-]. 68392561 LOC558804 427 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to Ring finger protein 14 [Danio rerio]. ci0100131213 ci0100131213 413 Ciona intestinalis metazoa>chordata ci0100131213 114583343 RNF25 410 Pan troglodytes metazoa>vertebrata PREDICTED: ring finger protein 25 isoform 3 [Pan troglodytes]. 114583345 RNF25 404 Pan troglodytes metazoa>vertebrata PREDICTED: ring finger protein 25 isoform 1 [Pan troglodytes]. Bflo1000000164 Bflo1000000164 398 Branchiostoma floridae metazoa>chordata fgenesh2_pm.scaffold_24000008 45550424 CG13344 374 Drosophila melanogaster metazoa>hexapoda CG13344-PA, isoform A [Drosophila melanogaster]. Bflo1000036047 Bflo1000036047 367 Branchiostoma floridae metazoa>chordata gw.468.72.1 66806621 DDBDRAFT_0187616 345 Dictyostelium discoideum AX4 mycetozoa>dictyosteliida hypothetical protein DDBDRAFT_0187616 [Dictyostelium discoideum 66565937 LOC551842 342 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG13344-PA, isoform A isoform 1 [Apis 70985074 AFUA_5G03000 336 Aspergillus fumigatus Af293 fungi>ascomycota Impact family protein [Aspergillus fumigatus Af293]. 110763765 LOC724849 329 Apis mellifera metazoa>hexapoda PREDICTED: similar to Gcn2 CG1609-PA, partial [Apis mellifera]. 8923819 IMPACT 320 Homo sapiens metazoa>vertebrata Impact homolog [Homo sapiens]. 6680447 Impact 318 Mus musculus metazoa>vertebrata imprinted and ancient [Mus musculus]. 47219321 GSTEN:00032736:G:001 317 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 58866042 Impact 317 Rattus norvegicus metazoa>vertebrata imprinted and ancient [Rattus norvegicus]. 115931317 LOC758373 316 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to Imprinted and ancient [Strongylocentrotus 68392559 LOC558736 311 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to Ring finger protein 14 [Danio rerio]. 156396655 NEMVEDRAFT_v1g92085 310 Nematostella vectensis metazoa predicted protein [Nematostella vectensis]. Mbre1000003516 Mbre1000003516 310 Monosiga brevicollis metazoa>choanoflagellida fgenesh2_pg.scaffold_4000220 46097319 UM01736.1 299 Ustilago maydis 521 fungi>basidiomycota hypothetical protein UM01736.1 [Ustilago maydis 521]. 85091150 NCU09542.1 299 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. Psoj1000013472 Psoj1000013472 298 Phytophthora sojae stramenopiles 141131 Pram1000007905 Pram1000007905 294 Phytophthora ramorum stramenopiles 75496 ci0100130613 ci0100130613 294 Ciona intestinalis metazoa>chordata ci0100130613 71994745 Y53G8AR.5 287 Caenorhabditis elegans metazoa>nematoda Y53G8AR.5 [Caenorhabditis elegans]. 47213740 GSTEN:00013011:G:001 285 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. Bflo1000040076 Bflo1000040076 282 Branchiostoma floridae metazoa>chordata e_gw.76.113.1 19115314 SPAC27E2.02 280 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPAC27E2.02 [Schizosaccharomyces pombe 972h-]. 47217977 GSTEN:00021291:G:001 279 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. Bflo1000039208 Bflo1000039208 271 Branchiostoma floridae metazoa>chordata e_gw.57.104.1 91094661 LOC661023 269 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG13344-PA, isoform A [Tribolium castaneum]. Ib#25.m01824 Ib#25.m01824 269 Toxoplasma gondii alveolata RWD domain-containing protein 50307629 KLLA0D16632g 267 Kluyveromyces lactis NRRL Y-1140 fungi>ascomycota unnamed protein product [Kluyveromyces lactis]. 6320356 GIR2 265 Saccharomyces cerevisiae fungi>ascomycota Gir2p [Saccharomyces cerevisiae]. 71995232 Y52B11A.2 257 Caenorhabditis elegans metazoa>nematoda Y52B11A.2a [Caenorhabditis elegans]. 45201140 AGOS_AGR045W 256 Ashbya gossypii ATCC 10895 fungi>ascomycota AGR045Wp [Ashbya gossypii ATCC 10895]. 15218023 AT1G51730 252 Arabidopsis thaliana viridiplantae RWD domain-containing protein [Arabidopsis thaliana]. Mbre1000006089 Mbre1000006089 250 Monosiga brevicollis metazoa>choanoflagellida estExt_fgenesh2_pg.C_20271 50547711 YALI0C01331g 245 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 58269324 CNG01320 245 Cryptococcus neoformans var. neoformans JEC21 fungi>basidiomycota hypothetical protein CNG01320 [Cryptococcus neoformans var. 28572074 CG5515 244 Drosophila melanogaster metazoa>hexapoda CG5515-PB, isoform B [Drosophila melanogaster]. Crei1000009193 Crei1000009193 245 Chlamydomonas reinhardtii viridiplantae fgenesh2_pg.C_scaffold_19000175 114609025 RWDD1 243 Pan troglodytes metazoa>vertebrata PREDICTED: RWD domain containing 1 isoform 4 [Pan troglodytes]. 21735427 Rwdd1 243 Mus musculus metazoa>vertebrata RWD domain containing 1 [Mus musculus]. 22129753 Rwdd1 243 Rattus norvegicus metazoa>vertebrata RWD domain containing 1 [Rattus norvegicus]. 55953123 RWDD1 243 Homo sapiens metazoa>vertebrata RWD domain containing 1 isoform a [Homo sapiens]. 17509259 T26E3.4 240 Caenorhabditis elegans metazoa>nematoda T26E3.4 [Caenorhabditis elegans]. 68435817 zgc:92801 240 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: zgc:92801 [Danio rerio]. 91091940 LOC656075 240 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG5515-PA, isoform A [Tribolium castaneum]. 48115538 LOC409681 239 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG5515-PA, isoform A [Apis mellifera]. Bflo1000027816 Bflo1000027816 238 Branchiostoma floridae metazoa>chordata estExt_fgenesh2_pg.C_790036 70993548 AFUA_4G12100 236 Aspergillus fumigatus Af293 fungi>ascomycota RWD domain protein (Gir2), putative [Aspergillus fumigatus Af293]. 58383719 ENSANGG00000017841 235 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000020330 [Anopheles gambiae str. PEST]. ci0100146916 ci0100146916 234 Ciona intestinalis metazoa>chordata ci0100145629 Psoj1000001657 Psoj1000001657 233 Phytophthora sojae stramenopiles 127587 156400027 NEMVEDRAFT_v1g36131 231 Nematostella vectensis metazoa predicted protein [Nematostella vectensis]. 46108494 FG01129.1 228 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG01129.1 [Gibberella zeae PH-1]. 85111207 NCU09381.1 227 Neurospora crassa OR74A fungi>ascomycota hypothetical protein [Neurospora crassa OR74A]. Bflo1000014876 Bflo1000014876 227 Branchiostoma floridae metazoa>chordata fgenesh2_pg.scaffold_202000018 Ngru1000009018 Ngru1000009018 226 Naegleria gruberi heterolobosea fgeneshNG_pg.scaffold_33000165 50550635 YALI0D13508g 223 Yarrowia lipolytica CLIB122 fungi>ascomycota hypothetical protein [Yarrowia lipolytica]. 19075467 SPCC1393.09c 215 Schizosaccharomyces pombe 972h- fungi>ascomycota hypothetical protein SPCC1393.09c [Schizosaccharomyces pombe 24585022 CG10343 214 Drosophila melanogaster metazoa>hexapoda CG10343-PA [Drosophila melanogaster]. Bflo1000029377 Bflo1000029377 204 Branchiostoma floridae metazoa>chordata estExt_fgenesh2_pg.C_1570080 58392186 ENSANGG00000009400 201 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000011889 [Anopheles gambiae str. PEST]. 110755042 LOC410964 192 Apis mellifera metazoa>hexapoda PREDICTED: similar to CG10343-PA [Apis mellifera]. 47218791 GSTEN:00021986:G:001 192 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. 114597051 RWDD4A 188 Pan troglodytes metazoa>vertebrata PREDICTED: RWD domain containing 4A isoform 3 [Pan troglodytes]. 114683912 LOC746498 188 Pan troglodytes metazoa>vertebrata PREDICTED: similar to RWD domain containing 4A [Pan troglodytes]. 22749371 RWDD4A 188 Homo sapiens metazoa>vertebrata RWD domain containing 4A [Homo sapiens]. 45356139 Rwdd4a 188 Mus musculus metazoa>vertebrata RWD domain containing 4A [Mus musculus]. 78097114 Rwdd4a 188 Rattus norvegicus metazoa>vertebrata RWD domain containing 4A [Rattus norvegicus]. 91091246 LOC656880 188 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to CG10343-PA [Tribolium castaneum]. 114597053 RWDD4A 187 Pan troglodytes metazoa>vertebrata PREDICTED: RWD domain containing 4A isoform 4 [Pan troglodytes]. 54400472 zgc:103545 186 Danio rerio metazoa>vertebrata>actinopterygii hypothetical protein LOC449812 [Danio rerio]. 156226640 NEMVEDRAFT_v1g160402 185 Nematostella vectensis metazoa predicted protein [Nematostella vectensis]. 91079412 LOC655512 183 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to Y52B11A.2a [Tribolium castaneum]. ci0100139746 ci0100139746 182 Ciona intestinalis metazoa>chordata ci0100139746 114597057 RWDD4A 178 Pan troglodytes metazoa>vertebrata PREDICTED: RWD domain containing 4A isoform 1 [Pan troglodytes]. 47209187 GSTEN:00009725:G:001 174 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. Pram1000014635 Pram1000014635 165 Phytophthora ramorum stramenopiles 49940 Bflo1000044940 Bflo1000044940 121 Branchiostoma floridae metazoa>chordata e_gw.506.31.1 71995236 Y52B11A.2 101 Caenorhabditis elegans metazoa>nematoda Y52B11A.2b [Caenorhabditis elegans]. 156226059 NEMVEDRAFT_v1g239604 662 Nematostella vectensis metazoa predicted protein [Nematostella vectensis]. Pram1000008033 Pram1000008033 414 Phytophthora ramorum stramenopiles 75340 23619480 PF13_0297 405 Plasmodium falciparum 3D7 alveolata hypothetical protein [Plasmodium falciparum 3D7]. 115930481 LOC578110 329 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: hypothetical protein [Strongylocentrotus purpuratus]. 114557939 LOC457042 322 Pan troglodytes metazoa>vertebrata PREDICTED: hypothetical protein [Pan troglodytes]. 55655678 LOC473941 319 Pan troglodytes metazoa>vertebrata PREDICTED: similar to chromosome 21 open reading frame 6 variant 8393018 RWDD2B 319 Homo sapiens metazoa>vertebrata RWD domain containing 2B [Homo sapiens]. 42550016 FG03119.1 297 Gibberella zeae PH-1 fungi>ascomycota hypothetical protein FG03119.1 [Gibberella zeae PH-1]. Bflo1000024953 Bflo1000024953 298 Branchiostoma floridae metazoa>chordata estExt_fgenesh2_pm.C_1380002 Bflo1000024954 Bflo1000024954 298 Branchiostoma floridae metazoa>chordata estExt_fgenesh2_pm.C_1380005 156390817 NEMVEDRAFT_v1g98046 296 Nematostella vectensis metazoa predicted protein [Nematostella vectensis]. 47221078 GSTEN:00035210:G:001 296 Tetraodon nigroviridis metazoa>vertebrata>actinopterygii unnamed protein product [Tetraodon nigroviridis]. ci0100134651 ci0100134651 297 Ciona intestinalis metazoa>chordata ci0100134651 114608280 RWDD2 292 Pan troglodytes metazoa>vertebrata PREDICTED: RWD domain containing 2 isoform 2 [Pan troglodytes]. 15529986 RWDD2A 292 Homo sapiens metazoa>vertebrata RWD domain containing 2A [Homo sapiens]. 21312304 Rwdd2a 292 Mus musculus metazoa>vertebrata RWD domain containing 2A [Mus musculus]. 34865383 Rwdd2_predicted 292 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to RWD domain containing 2 [Rattus norvegicus]. 8393889 ORF5 291 Mus musculus metazoa>vertebrata hypothetical protein LOC53858 [Mus musculus]. 94400661 ORF5 291 Mus musculus metazoa>vertebrata PREDICTED: similar to Protein C21orf6 homolog [Mus musculus]. Mbre1000000887 Mbre1000000887 292 Monosiga brevicollis metazoa>choanoflagellida fgenesh1_pg.scaffold_9000212 27671236 RGD1305062 290 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to Protein C21orf6 homolog [Rattus norvegicus]. 70996855 AFUA_5G14750 290 Aspergillus fumigatus Af293 fungi>ascomycota DUF1115 domain protein [Aspergillus fumigatus Af293]. Bflo1000038170 Bflo1000038170 291 Branchiostoma floridae metazoa>chordata e_gw.35.176.1 68394741 LOC566444 289 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: similar to CG30338-PA isoform 1 [Danio rerio]. 24652142 CG30338 288 Drosophila melanogaster metazoa>hexapoda CG30338-PA [Drosophila melanogaster]. Bflo1000011104 Bflo1000011104 289 Branchiostoma floridae metazoa>chordata fgenesh2_pg.scaffold_136000070 91081553 LOC663945 278 Tribolium castaneum metazoa>hexapoda PREDICTED: similar to RWD domain-containing protein 2 [Tribolium Bflo1000004634 Bflo1000004634 278 Branchiostoma floridae metazoa>chordata fgenesh2_pg.scaffold_28000037 Bflo1000042783 Bflo1000042783 278 Branchiostoma floridae metazoa>chordata e_gw.318.73.1 114608278 RWDD2 270 Pan troglodytes metazoa>vertebrata PREDICTED: similar to OTTHUMP00000016790 isoform 1 [Pan 58394267 ENSANGG00000006591 269 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000008752 [Anopheles gambiae str. PEST]. 109465507 Rwdd3 267 Rattus norvegicus metazoa>vertebrata PREDICTED: similar to RWD domain-containing protein 3 [Rattus 39930449 Rwdd3 267 Mus musculus metazoa>vertebrata RWD domain containing 3 [Mus musculus]. ci0100140215 ci0100140215 244 Ciona intestinalis metazoa>chordata ci0100140215 110768026 LOC727015 242 Apis mellifera metazoa>hexapoda PREDICTED: similar to RWD domain containing 2 [Apis mellifera]. 115933574 LOC582453 234 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to X2CR1, partial [Strongylocentrotus 7661656 RWDD3 195 Homo sapiens metazoa>vertebrata RWD domain containing 3 [Homo sapiens]. 57908910 ENSANGG00000024642 175 Anopheles gambiae str. PEST metazoa>hexapoda ENSANGP00000026767 [Anopheles gambiae str. PEST]. 68355746 LOC554404 141 Danio rerio metazoa>vertebrata>actinopterygii PREDICTED: hypothetical protein [Danio rerio]. 115957054 LOC577333 523 Strongylocentrotus purpuratus metazoa>echinodermata PREDICTED: similar to MGC85593 protein [Strongylocentrotus Bflo1000035554 Bflo1000035554 516 Branchiostoma floridae metazoa>chordata gw.410.54.1 Bflo1000035563 Bflo1000035563 498 Branchiostoma floridae metazoa>chordata gw.920.15.1 Ngru1000004988 Ngru1000004988 1552 Naegleria gruberi heterolobosea estExt_fgeneshHS_pg.C_420068 74026362 Tb11.01.8680 912 Trypanosoma brucei TREU927 euglenozoa>kinetoplastida hypothetical protein Tb11.01.8680 [Trypanosoma brucei TREU927]. 71407364 Tc00.1047053503749.10 884 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein Tc00.1047053503749.10 [Trypanosoma cruzi 71419936 Tc00.1047053511021.99 382 Trypanosoma cruzi strain CL Brener euglenozoa>kinetoplastida hypothetical protein Tc00.1047053511021.99 [Trypanosoma cruzi