BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= PG0589
(183 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34540452|ref|NP_904931.1| HDIG domain protein [Porphyrom... 369 e-101
gi|29347544|ref|NP_811047.1| putative HD superfamily hydrol... 211 1e-53
gi|150006629|ref|YP_001301373.1| hypothetical protein BVU_4... 209 8e-53
gi|156109573|gb|EDO11318.1| hypothetical protein BACOVA_032... 208 1e-52
gi|156861303|gb|EDO54734.1| hypothetical protein BACUNI_017... 206 5e-52
gi|153808758|ref|ZP_01961426.1| hypothetical protein BACCAC... 205 1e-51
gi|60683060|ref|YP_213204.1| hypothetical protein BF3610 [B... 203 4e-51
gi|53715102|ref|YP_101094.1| putative HD superfamily hydrol... 202 5e-51
gi|154491809|ref|ZP_02031435.1| hypothetical protein PARMER... 197 3e-49
gi|150010285|ref|YP_001305028.1| hypothetical protein BDI_3... 195 1e-48
gi|77919758|ref|YP_357573.1| predicted HD domain containing... 166 8e-40
gi|95928779|ref|ZP_01311525.1| metal dependent phosphohydro... 156 4e-37
gi|67462517|ref|XP_647920.1| conserved hypothetical protein... 152 9e-36
gi|145618872|ref|ZP_01774927.1| metal dependent phosphohydr... 145 1e-33
gi|78222829|ref|YP_384576.1| HDIG [Geobacter metallireducen... 144 3e-33
gi|39996785|ref|NP_952736.1| HD domain protein [Geobacter s... 144 3e-33
gi|121541055|ref|ZP_01672812.1| HD domain protein [Candidat... 143 5e-33
gi|67462591|ref|XP_647957.1| conserved hypothetical protein... 143 5e-33
gi|148264586|ref|YP_001231292.1| metal dependent phophohydr... 138 1e-31
gi|110601108|ref|ZP_01389309.1| uncharacterized domain HDIG... 136 5e-31
gi|118744236|ref|ZP_01592232.1| HD domain protein [Geobacte... 135 1e-30
gi|150385091|ref|ZP_01923745.1| metal dependent phosphohydr... 133 6e-30
gi|118579715|ref|YP_900965.1| HDIG [Pelobacter propionicus ... 121 2e-26
gi|111223123|ref|YP_713917.1| conserved hypothetical protei... 91 2e-17
gi|23464811|ref|NP_695414.1| hypothetical protein BL0196 [B... 82 2e-14
gi|23335965|ref|ZP_00121195.1| COG1418: Predicted HD superf... 81 2e-14
gi|147921601|ref|YP_684582.1| hypothetical protein LRC275 [... 80 7e-14
gi|13541902|ref|NP_111590.1| Predicted hydrolase (HD superf... 79 1e-13
gi|48477768|ref|YP_023474.1| metal dependent phosphohydrola... 74 4e-12
gi|148642692|ref|YP_001273205.1| predicted hydrolase, HD su... 74 6e-12
gi|15679662|ref|NP_276779.1| hypothetical protein MTH1668 [... 72 2e-11
gi|16081979|ref|NP_394389.1| hypothetical protein Ta0931 [T... 70 4e-11
gi|20093932|ref|NP_613779.1| Predicted HD superfamily hydro... 69 1e-10
gi|15668959|ref|NP_247763.1| hypothetical protein MJ0778 [M... 64 6e-09
gi|73667744|ref|YP_303759.1| metal-dependent phosphohydrola... 63 9e-09
gi|21226795|ref|NP_632717.1| hypothetical protein MM_0693 [... 63 1e-08
gi|84490061|ref|YP_448293.1| hypothetical protein Msp_1273 ... 61 3e-08
gi|154489116|ref|ZP_02029965.1| hypothetical protein BIFADO... 61 3e-08
gi|119026538|ref|YP_910383.1| hypothetical protein BAD_1520... 60 4e-08
gi|150399782|ref|YP_001323549.1| metal dependent phosphohyd... 60 7e-08
gi|20092668|ref|NP_618743.1| metal-dependent phosphohydrola... 59 1e-07
gi|134046669|ref|YP_001098154.1| metal dependent phosphohyd... 54 4e-06
gi|150402958|ref|YP_001330252.1| metal dependent phosphohyd... 53 7e-06
gi|126008887|ref|ZP_01709458.1| hypothetical protein Faci_0... 53 1e-05
>gi|34540452|ref|NP_904931.1| HDIG domain protein [Porphyromonas gingivalis W83]
gi|34396765|gb|AAQ65830.1| HDIG domain protein [Porphyromonas gingivalis W83]
Length = 183
Score = 369 bits (948), Expect = e-101, Method: Composition-based stats.
Identities = 183/183 (100%), Positives = 183/183 (100%)
Query: 1 MMDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIG 60
MMDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIG
Sbjct: 1 MMDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIG 60
Query: 61 IFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIAL 120
IFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIAL
Sbjct: 61 IFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIAL 120
Query: 121 PPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALFKI 180
PPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALFKI
Sbjct: 121 PPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALFKI 180
Query: 181 PLG 183
PLG
Sbjct: 181 PLG 183
>gi|29347544|ref|NP_811047.1| putative HD superfamily hydrolase [Bacteroides thetaiotaomicron
VPI-5482]
gi|29339444|gb|AAO77241.1| putative HD superfamily hydrolase [Bacteroides thetaiotaomicron
VPI-5482]
Length = 178
Score = 211 bits (538), Expect = 1e-53, Method: Composition-based stats.
Identities = 101/177 (57%), Positives = 132/177 (74%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+PI II+K+Y + T Q HIL+ HS VA AL+IV+ HP L +R FV EAA+LHDIGI
Sbjct: 1 MNPIEIIDKFYPQDTEQRHILLIHSLSVAQKALKIVDAHPNLPINRSFVREAALLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
F+TDA +I CFG+ PYI HGY+GA++LRKEG+ RHALVCERHTG+GLT E+I RQ+ +P
Sbjct: 61 FMTDAPTIQCFGEHPYIAHGYLGADLLRKEGFERHALVCERHTGAGLTLEEIIERQLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P ++EE+I+C+ADKFFSKT L +K +E R+S+ YG + L RFD +LF
Sbjct: 121 HREMVPVTLEEQIICFADKFFSKTHLDEEKTVEKARKSIAKYGEEGLNRFDGWCSLF 177
>gi|150006629|ref|YP_001301373.1| hypothetical protein BVU_4150 [Bacteroides vulgatus ATCC 8482]
gi|149935053|gb|ABR41751.1| conserved hypothetical protein [Bacteroides vulgatus ATCC 8482]
Length = 178
Score = 209 bits (531), Expect = 8e-53, Method: Composition-based stats.
Identities = 97/171 (56%), Positives = 126/171 (73%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
MD ++IINKYY E HIL+ HSR VA AL I HPEL D+ F+EEAAMLHDIGI
Sbjct: 1 MDALAIINKYYPEDNELKHILLAHSRSVADKALWIAGKHPELNLDKQFLEEAAMLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
F+TDAE I CFG PYI HGY+GA+++RKEG+PRHALVCERHTG+G++ + I +Q+ +P
Sbjct: 61 FMTDAEGICCFGSYPYICHGYLGADLMRKEGFPRHALVCERHTGAGMSLQSIIDQQLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFD 172
P S+EE+++C+ADKFFSKT L R+K +E +S+ YG D + RF+
Sbjct: 121 HRNMVPVSLEEQVICFADKFFSKTHLDREKSVEKALKSISRYGEDGIIRFN 171
>gi|156109573|gb|EDO11318.1| hypothetical protein BACOVA_03221 [Bacteroides ovatus ATCC 8483]
Length = 225
Score = 208 bits (529), Expect = 1e-52, Method: Composition-based stats.
Identities = 98/177 (55%), Positives = 131/177 (74%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+P II+KYY E T Q ILV HS V+ A+++++ HPEL+ +R FV+EAA+LHDIGI
Sbjct: 48 MNPYEIIDKYYPENTQQRQILVIHSLAVSGKAMKMLDAHPELRLNRSFVKEAALLHDIGI 107
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
F TDA +I CFG PYI HGY+GA ILR EG+P+HALVCERHTG+GL+ EDI A+Q+ +P
Sbjct: 108 FQTDAPTIQCFGTHPYIAHGYLGAEILRAEGFPQHALVCERHTGAGLSLEDIIAQQLPVP 167
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P ++EE+++C+ADKFFSKT L +K +E R+S+ YG + L RFD +LF
Sbjct: 168 HREMLPITLEEQLICFADKFFSKTHLDEEKTVEKARQSIAKYGEEGLSRFDRWCSLF 224
>gi|156861303|gb|EDO54734.1| hypothetical protein BACUNI_01719 [Bacteroides uniformis ATCC 8492]
Length = 178
Score = 206 bits (524), Expect = 5e-52, Method: Composition-based stats.
Identities = 98/171 (57%), Positives = 126/171 (73%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+PI IINKYY E HIL+ HSR VA +L I + HPEL D+ F+ EAAMLHDIGI
Sbjct: 1 MNPIDIINKYYPEENELRHILLTHSRSVADKSLWIADRHPELSLDKDFLYEAAMLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
FLTDA I CFG +PYI HGY+GA+++R EGYPRHALVCERHTG+GL+ E I A+ + +P
Sbjct: 61 FLTDAAGIHCFGDKPYICHGYLGADLIRGEGYPRHALVCERHTGAGLSLEGIIAQDLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFD 172
P S+EE+ +C+ADKF+SKT L ++K +E R+S+ YG + +RRFD
Sbjct: 121 HREMVPVSLEEQAICFADKFYSKTHLEKEKSVEKARKSLERYGEEGVRRFD 171
>gi|153808758|ref|ZP_01961426.1| hypothetical protein BACCAC_03057 [Bacteroides caccae ATCC 43185]
gi|149128584|gb|EDM19802.1| hypothetical protein BACCAC_03057 [Bacteroides caccae ATCC 43185]
Length = 178
Score = 205 bits (521), Expect = 1e-51, Method: Composition-based stats.
Identities = 97/177 (54%), Positives = 130/177 (73%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+P II+KYY E T Q ILV HS VA A++I++ HPEL+ +R FV+EAA+LHDIGI
Sbjct: 1 MNPYEIIDKYYPENTEQRQILVIHSLSVAGKAMKILDAHPELRLNRSFVKEAALLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
F T+A +I CFG PYI HGY+GA ILR+EG+P+HALVCERHTG+GL+ +DI +Q+ +P
Sbjct: 61 FQTNAPTIQCFGSHPYIAHGYLGAEILREEGFPQHALVCERHTGAGLSLQDIVDQQLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P ++EE+++C+ADKFFSKT L +K +E R S+ YG + L RFD +LF
Sbjct: 121 HREMLPITLEEQLICFADKFFSKTHLDEEKSVEKARHSIAKYGEEGLSRFDRWCSLF 177
>gi|60683060|ref|YP_213204.1| hypothetical protein BF3610 [Bacteroides fragilis NCTC 9343]
gi|60494494|emb|CAH09291.1| conserved hypothetical protein [Bacteroides fragilis NCTC 9343]
Length = 178
Score = 203 bits (516), Expect = 4e-51, Method: Composition-based stats.
Identities = 97/177 (54%), Positives = 126/177 (71%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M + +I+KYY + HIL HSR VA AL I HPEL D +F+EEAAMLHDIGI
Sbjct: 1 MKVLDLIDKYYPQDNELKHILNVHSRSVADKALWIAGKHPELNLDTVFLEEAAMLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
FLT A I CFG EPYI HGY+GA ++RKEG+PRHALVCERHTG+GL+ +DI +++ +P
Sbjct: 61 FLTHAPGIQCFGTEPYICHGYLGAGLVRKEGFPRHALVCERHTGAGLSLKDIMDQKLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P S+EE+++C+ADKFFSKT L R+K +E R+S+ YG + L+RF+ LF
Sbjct: 121 HREMLPVSMEEQVICFADKFFSKTHLDREKTVEGARKSIAKYGDEGLQRFNNWCKLF 177
>gi|53715102|ref|YP_101094.1| putative HD superfamily hydrolase [Bacteroides fragilis YCH46]
gi|52217967|dbj|BAD50560.1| putative HD superfamily hydrolase [Bacteroides fragilis YCH46]
Length = 178
Score = 202 bits (515), Expect = 5e-51, Method: Composition-based stats.
Identities = 97/177 (54%), Positives = 126/177 (71%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M + +I+KYY + HIL HSR VA AL I HPEL D +F+EEAAMLHDIGI
Sbjct: 1 MKVLDLIDKYYPQDNELKHILNVHSRSVADKALWIAVKHPELNLDTVFLEEAAMLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
FLT A I CFG EPYI HGY+GA ++RKEG+PRHALVCERHTG+GL+ +DI +++ +P
Sbjct: 61 FLTHAPGIQCFGTEPYICHGYLGAGLVRKEGFPRHALVCERHTGAGLSLKDIMDQKLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P S+EE+++C+ADKFFSKT L R+K +E R+S+ YG + L+RF+ LF
Sbjct: 121 HREMLPVSMEEQVICFADKFFSKTHLDREKTVEGARKSIAKYGDEGLQRFNNWCKLF 177
>gi|154491809|ref|ZP_02031435.1| hypothetical protein PARMER_01430 [Parabacteroides merdae ATCC
43184]
gi|154088050|gb|EDN87095.1| hypothetical protein PARMER_01430 [Parabacteroides merdae ATCC
43184]
Length = 180
Score = 197 bits (500), Expect = 3e-49, Method: Composition-based stats.
Identities = 94/177 (53%), Positives = 123/177 (69%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+P+ II KYY G+ Y ILV HSR VA AL I +HPE+ D FVEEAAMLHDIGI
Sbjct: 1 MNPLDIIAKYYPVGSEAYRILVIHSRSVADKALAIARMHPEMNLDLTFVEEAAMLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
F +A I C G YI HGY+GA ++R EGYPRHA VCERHTG+G+T I R + LP
Sbjct: 61 FRCNAPDIDCHGDAEYICHGYLGAELMRAEGYPRHARVCERHTGTGITLAMIEERGLPLP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
+ P+++EE+++CYADKF+SKTKL ++K +E V++ + YG +++ RFD LF
Sbjct: 121 HRDFMPETLEEQLICYADKFYSKTKLDKEKSVEKVKQGLSKYGNETVERFDNWCKLF 177
>gi|150010285|ref|YP_001305028.1| hypothetical protein BDI_3714 [Parabacteroides distasonis ATCC
8503]
gi|149938709|gb|ABR45406.1| conserved hypothetical protein [Parabacteroides distasonis ATCC
8503]
Length = 180
Score = 195 bits (495), Expect = 1e-48, Method: Composition-based stats.
Identities = 91/177 (51%), Positives = 125/177 (70%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M P+ II KYY E ++ Y ILV HSR VA AL + +HPE+ D F+EEA MLHDIGI
Sbjct: 1 MKPLDIIKKYYPESSDAYRILVTHSRSVADKALALARLHPEMNLDLTFIEEATMLHDIGI 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
FL +A I C G+ YI HGY+GA+++RKEGYPRHALVCERHTG+GL+ I R + +P
Sbjct: 61 FLCNAPDIDCHGEADYICHGYLGADLMRKEGYPRHALVCERHTGTGLSLAMIEERNLPVP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P S+EE+++C+ADKFFSKTKL ++K + +++S+ YG +++ +F+ LF
Sbjct: 121 HRDMRPVSLEEQLICFADKFFSKTKLTKEKPADKIKQSLSKYGNETVEQFEHWCKLF 177
>gi|77919758|ref|YP_357573.1| predicted HD domain containing protein [Pelobacter carbinolicus DSM
2380]
gi|77545841|gb|ABA89403.1| predicted HD domain containing protein [Pelobacter carbinolicus DSM
2380]
Length = 182
Score = 166 bits (419), Expect = 8e-40, Method: Composition-based stats.
Identities = 82/182 (45%), Positives = 116/182 (63%), Gaps = 2/182 (1%)
Query: 1 MMDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIG 60
M+D I++++KYY + + IL+ HSR VAA A I P+ D FV EAA+LHDIG
Sbjct: 1 MIDAIALLDKYYIPASQAHRILLAHSRSVAAKATDIAGSLPDGSVDVTFVTEAALLHDIG 60
Query: 61 IFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIAL 120
I T A ++ CFG PY+ HG G +L EG PRHALVCERH G GLTS +I +Q+ L
Sbjct: 61 ICYTSAAALGCFGDLPYLCHGLKGRQLLEAEGLPRHALVCERHIGVGLTSAEIIRQQLPL 120
Query: 121 PPGIYTPQSIEEKIVCYADKFFSKTKLH--RQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
P P ++EE+I+ YAD FFSK + R++ ++VR S++ +G+D + FD H++F
Sbjct: 121 PERDMLPTTLEEQIIAYADLFFSKNPANHGRERTPDEVRASLMRFGSDKVDIFDRWHSMF 180
Query: 179 KI 180
+
Sbjct: 181 TV 182
>gi|95928779|ref|ZP_01311525.1| metal dependent phosphohydrolase [Desulfuromonas acetoxidans DSM
684]
gi|95135124|gb|EAT16777.1| metal dependent phosphohydrolase [Desulfuromonas acetoxidans DSM
684]
Length = 184
Score = 156 bits (395), Expect = 4e-37, Method: Composition-based stats.
Identities = 86/183 (46%), Positives = 114/183 (62%), Gaps = 6/183 (3%)
Query: 1 MMDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQA---DRLFVEEAAMLH 57
M DPI II YY T +HIL+ HS+ VA A+ I E H Q D F+++AA+LH
Sbjct: 1 MTDPIEIITAYYPPHTRAHHILLRHSQQVAEKAISIAE-HLCRQGEIIDLEFIQQAALLH 59
Query: 58 DIGIFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQ 117
DIGIF A ++ C+G+ PY+ HG GA IL+ EG PRHA VCERHTG GLT+E+I +
Sbjct: 60 DIGIFRVHAPALGCYGQLPYLHHGIEGAKILQAEGLPRHANVCERHTGVGLTAEEITQNK 119
Query: 118 IALPPGIYTPQSIEEKIVCYADKFFSKTKLH--RQKKLEDVRRSMLSYGADSLRRFDEMH 175
+ LP P ++EE+I+ YAD FFSK H RQ+ +E VR S+ ++G + FD H
Sbjct: 120 LGLPRRNMIPTTVEEQIIAYADLFFSKNPHHLDRQRPVEKVRMSLCTFGEEKGEIFDRWH 179
Query: 176 ALF 178
F
Sbjct: 180 RRF 182
>gi|67462517|ref|XP_647920.1| conserved hypothetical protein [Entamoeba histolytica HM-1:IMSS]
gi|67468224|ref|XP_650165.1| conserved hypothetical protein [Entamoeba histolytica HM-1:IMSS]
Length = 188
Score = 152 bits (384), Expect = 9e-36, Method: Composition-based stats.
Identities = 77/179 (43%), Positives = 109/179 (60%), Gaps = 1/179 (0%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
+DP I+ KYY E HIL+EH + + ++ HPE + F++E A LHDIGI
Sbjct: 10 IDPFKILEKYYKELPIAKHILIEHGKSIYGKCEQVNAKHPEYHINMEFIKEVAYLHDIGI 69
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
FL D+ C GKEPYI HG +GA+ILR+ G HA V ERHTGSG+ I + + LP
Sbjct: 70 FLVDSPQFGCNGKEPYIKHGILGADILRELGLEYHARVAERHTGSGIDPTQIVEQHLPLP 129
Query: 122 PG-IYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALFK 179
I P++IEEK++CYADKFFSK+ L + +R + +G D ++R D++ +F+
Sbjct: 130 TDRILLPKTIEEKLLCYADKFFSKSHLEDTLTQQMIREKLQKHGKDVIQRLDDLFKMFE 188
>gi|145618872|ref|ZP_01774927.1| metal dependent phosphohydrolase [Geobacter bemidjiensis Bem]
gi|144944798|gb|EDJ79868.1| metal dependent phosphohydrolase [Geobacter bemidjiensis Bem]
Length = 185
Score = 145 bits (365), Expect = 1e-33, Method: Composition-based stats.
Identities = 76/173 (43%), Positives = 106/173 (61%), Gaps = 2/173 (1%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+P +++ KYY + I+ HSR+VA AL I QA+ F+EEAA+LHDIG+
Sbjct: 1 MNPRALLEKYYEDNDAALEIVYRHSRNVADKALAIAVTAGLPQAELDFIEEAALLHDIGV 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
A + CFGK PY+ HG +G IL EG PRHA+VCERH G GLT+ DI A+ + LP
Sbjct: 61 SRIYAPKLNCFGKAPYVWHGVIGREILDAEGLPRHAMVCERHIGVGLTAADIVAQNLRLP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKT--KLHRQKKLEDVRRSMLSYGADSLRRFD 172
+P + E+IV AD FFSK +L +K + VR +L +GA+ ++ F+
Sbjct: 121 VREMSPVTTSERIVALADLFFSKKGGELDLEKSTQQVRCDLLRFGAEKVQIFE 173
>gi|78222829|ref|YP_384576.1| HDIG [Geobacter metallireducens GS-15]
gi|78194084|gb|ABB31851.1| HDIG [Geobacter metallireducens GS-15]
Length = 181
Score = 144 bits (363), Expect = 3e-33, Method: Composition-based stats.
Identities = 76/174 (43%), Positives = 107/174 (61%), Gaps = 2/174 (1%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M+ I+ +++ E T I++EHSR VA ALRI + D F+EEAA+LHDIG+
Sbjct: 1 MNVEHILTRHFGEETRACAIVLEHSRMVADKALRIARTLNDPDLDLRFIEEAALLHDIGV 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
TD+ I C G PYILHG +G IL EG PRHA+VCERH G GLT +DI + + LP
Sbjct: 61 CGTDSPGIGCSGDSPYILHGIIGREILEAEGLPRHAMVCERHIGVGLTVDDIVRQGLPLP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSK--TKLHRQKKLEDVRRSMLSYGADSLRRFDE 173
P + EE+I+CYAD FFSK L+ +K ++R+ ++ +G + F++
Sbjct: 121 LREMVPVTREERIICYADLFFSKKGNSLNHEKSPPEIRKGLIRHGEHRVAIFEQ 174
>gi|39996785|ref|NP_952736.1| HD domain protein [Geobacter sulfurreducens PCA]
gi|39983673|gb|AAR35063.1| HD domain protein [Geobacter sulfurreducens PCA]
Length = 181
Score = 144 bits (362), Expect = 3e-33, Method: Composition-based stats.
Identities = 79/181 (43%), Positives = 109/181 (60%), Gaps = 2/181 (1%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
M P +++ +++ T I++ HSR VAA AL + + D F+EEAA+LHDIG+
Sbjct: 1 MTPENLLTRHFGPATTACGIVLAHSRHVAAKALAVARRLRDPLLDLRFIEEAALLHDIGV 60
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
T++ I C G+ PYILHG +G IL EG PRHALVCERH G GLT EDI + + LP
Sbjct: 61 CRTNSTGIGCTGEAPYILHGIIGREILEAEGLPRHALVCERHIGVGLTVEDIERQSLPLP 120
Query: 122 PGIYTPQSIEEKIVCYADKFFSKT--KLHRQKKLEDVRRSMLSYGADSLRRFDEMHALFK 179
P + EE+IVC+AD FFSK L +K ++VR ++ YG + F+E A F
Sbjct: 121 RRDMVPLTREERIVCFADLFFSKKPRSLDHEKHPDEVRANLRRYGDHKVAIFEEWLAEFA 180
Query: 180 I 180
+
Sbjct: 181 V 181
>gi|121541055|ref|ZP_01672812.1| HD domain protein [Candidatus Desulfococcus oleovorans Hxd3]
gi|121519087|gb|EAX55938.1| HD domain protein [Candidatus Desulfococcus oleovorans Hxd3]
Length = 193
Score = 143 bits (360), Expect = 5e-33, Method: Composition-based stats.
Identities = 74/163 (45%), Positives = 100/163 (61%), Gaps = 2/163 (1%)
Query: 4 PISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFL 63
P+ II +YY G+ + ++ H V AL + + + D F+EEAA+LHDIGIF
Sbjct: 12 PLEIIKRYYDPGSRAFESMIPHCTRVMEKALAVARVVAAMHPDMRFIEEAALLHDIGIFK 71
Query: 64 TDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALPPG 123
A I C G PY+ HG +G +L KEG PRHALVCERH G+G+T+E+I A + LP
Sbjct: 72 VHAPDIGCTGDAPYVCHGVLGRELLEKEGLPRHALVCERHVGTGITAEEIVAAGLPLPVR 131
Query: 124 IYTPQSIEEKIVCYADKFFSKTKL--HRQKKLEDVRRSMLSYG 164
P S+EE IV YADKFFSK +R+K ++++ R M YG
Sbjct: 132 DMCPVSLEEIIVAYADKFFSKNPKAGNREKPVDEIAREMAKYG 174
>gi|67462591|ref|XP_647957.1| conserved hypothetical protein [Entamoeba histolytica HM-1:IMSS]
Length = 177
Score = 143 bits (360), Expect = 5e-33, Method: Composition-based stats.
Identities = 75/178 (42%), Positives = 104/178 (58%), Gaps = 10/178 (5%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
+DP I+ KYY E HIL+EH + + ++ HPE + F++E A LHDIGI
Sbjct: 10 IDPFKILEKYYKELPIAKHILIEHGKSIYGKCEQVNAKHPEYHINMEFIKEVAYLHDIGI 69
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
FL D+ C GKEPYI HG +GA+ILR+ G HA V ERHTGS L P
Sbjct: 70 FLVDSPQFGCNGKEPYIKHGILGADILRELGLEYHARVAERHTGSELIQ----------P 119
Query: 122 PGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYGADSLRRFDEMHALFK 179
I P++IEEK++CYADKFFSK+ L + +R + +G D ++R D++ +F+
Sbjct: 120 KLILLPKTIEEKLLCYADKFFSKSHLEDTLTQQMIREKLQKHGKDVIQRLDDLFKMFE 177
>gi|148264586|ref|YP_001231292.1| metal dependent phophohydrolase [Geobacter uraniumreducens Rf4]
gi|146398086|gb|ABQ26719.1| metal dependent phophohydrolase [Geobacter uraniumreducens Rf4]
Length = 180
Score = 138 bits (348), Expect = 1e-31, Method: Composition-based stats.
Identities = 78/184 (42%), Positives = 109/184 (59%), Gaps = 8/184 (4%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQA--DRLFVEEAAMLHDI 59
MD I+++ KY+ + I+ +HSR VA AL I L A D F+EEAA++HDI
Sbjct: 1 MDAIALLKKYFVN-QEAFEIVAKHSRMVADKALGIAS---ALNAGIDLTFIEEAALVHDI 56
Query: 60 GIFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIA 119
G+ A + C+GK PYI HG +G IL KEG+P HA+VCERH G GLT +DI +++
Sbjct: 57 GVSKIYAPKLNCYGKSPYICHGVLGREILEKEGFPVHAMVCERHIGVGLTVDDIIRQKMP 116
Query: 120 LPPGIYTPQSIEEKIVCYADKFFSKT--KLHRQKKLEDVRRSMLSYGADSLRRFDEMHAL 177
LP P S EEKI+C+AD ++SK L R+ E+VR ++ +G + FD+ A
Sbjct: 117 LPVREMCPLSQEEKIICFADLYYSKNPESLSRENSHEEVRTALKKFGTHKVAIFDQWLAE 176
Query: 178 FKIP 181
P
Sbjct: 177 LGKP 180
>gi|110601108|ref|ZP_01389309.1| uncharacterized domain HDIG [Geobacter sp. FRC-32]
gi|110548180|gb|EAT61405.1| uncharacterized domain HDIG [Geobacter sp. FRC-32]
Length = 189
Score = 136 bits (343), Expect = 5e-31, Method: Composition-based stats.
Identities = 75/177 (42%), Positives = 106/177 (59%), Gaps = 4/177 (2%)
Query: 2 MDPISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGI 61
MD +++ KY++ I+++HSR VA AL + + D F+EEAA+LHDIG+
Sbjct: 1 MDAAALLKKYFSNEA-ALEIVLKHSRLVADKALEVAG-GLGIPIDLKFIEEAALLHDIGV 58
Query: 62 FLTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALP 121
A + CFG +PYI HG G IL EG PRHA+VCERH G GLT+EDI +++ LP
Sbjct: 59 SRVHAPKMFCFGSQPYICHGITGREILETEGLPRHAMVCERHIGVGLTAEDIRRQKLPLP 118
Query: 122 PGIYTPQSIEEKIVCYADKFFSKT--KLHRQKKLEDVRRSMLSYGADSLRRFDEMHA 176
P S+EE+I+C+AD F+SK + K E+VR S+ +G + FD +A
Sbjct: 119 ARDMVPLSLEEEIICFADLFYSKIPDSVTVMKSREEVRASLEKFGEGKITIFDRWYA 175
>gi|118744236|ref|ZP_01592232.1| HD domain protein [Geobacter lovleyi SZ]
gi|118682915|gb|EAV89318.1| HD domain protein [Geobacter lovleyi SZ]
Length = 181
Score = 135 bits (340), Expect = 1e-30, Method: Composition-based stats.
Identities = 69/154 (44%), Positives = 95/154 (61%), Gaps = 2/154 (1%)
Query: 21 ILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILH 80
IL+ H R VA AL + R V EAA LHDIG+ +A IAC G EPYI H
Sbjct: 19 ILMIHGRMVAGKALSACAVVNADSETRRLVIEAAYLHDIGVCKVNAPDIACHGAEPYIRH 78
Query: 81 GYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
G +G +L EG P HAL+CERHTG GLT DI ++ + LP TP+++ E+I+CYAD
Sbjct: 79 GVLGRELLDAEGLPLHALICERHTGVGLTINDITSQNLPLPQRDMTPETLAERIICYADL 138
Query: 141 FFSKT--KLHRQKKLEDVRRSMLSYGADSLRRFD 172
FFSK +L ++K +E +R+++ +G D + F+
Sbjct: 139 FFSKNPDRLEKEKSVEKIRKNLAKFGDDKVAIFE 172
>gi|150385091|ref|ZP_01923745.1| metal dependent phosphohydrolase [Victivallis vadensis ATCC
BAA-548]
gi|150258534|gb|EDM95803.1| metal dependent phosphohydrolase [Victivallis vadensis ATCC
BAA-548]
Length = 201
Score = 133 bits (334), Expect = 6e-30, Method: Composition-based stats.
Identities = 65/141 (46%), Positives = 90/141 (63%), Gaps = 6/141 (4%)
Query: 46 DRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILHGYMGANILRKEGYPR------HALV 99
D + AMLHDIGI DA I C G EPYI HG +GA +LR+ G A +
Sbjct: 60 DARLAADGAMLHDIGIGRCDAPKILCEGSEPYITHGVIGARMLREYGAANGLDLEAFARI 119
Query: 100 CERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRS 159
CERHTGSG+T+ ++ A+ + +P Y P+++EEK+VC ADKFFSK+ ++K L+ +R S
Sbjct: 120 CERHTGSGITAAEVRAQALPIPVRDYLPETLEEKLVCLADKFFSKSGDMKEKPLDRIRCS 179
Query: 160 MLSYGADSLRRFDEMHALFKI 180
M +G D+ RFD + ALFK+
Sbjct: 180 MRKFGPDAAARFDALCALFKV 200
>gi|118579715|ref|YP_900965.1| HDIG [Pelobacter propionicus DSM 2379]
gi|118502425|gb|ABK98907.1| HDIG [Pelobacter propionicus DSM 2379]
Length = 165
Score = 121 bits (303), Expect = 2e-26, Method: Composition-based stats.
Identities = 66/160 (41%), Positives = 91/160 (56%), Gaps = 2/160 (1%)
Query: 21 ILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILH 80
+++ H V+ LA +I + + F+ +AA LHDIGI A I G PYI+H
Sbjct: 1 MVITHGSMVSHLAQKIGRVLGVSAGELTFLGQAAQLHDIGICRVRAPEIGLLGSYPYIMH 60
Query: 81 GYMGANILRKEGYPRHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
G +G IL EG PRHALVCERH G GLT +DI ++++LP P+++ E+IVC+AD
Sbjct: 61 GILGREILEAEGLPRHALVCERHIGVGLTEDDITVQELSLPLRDMAPRNLTEEIVCFADL 120
Query: 141 FFSKTK--LHRQKKLEDVRRSMLSYGADSLRRFDEMHALF 178
FFSK L + K VR + +G L+ FD A F
Sbjct: 121 FFSKYPGGLEKMKTPARVREKLSQFGEAKLQIFDRWLARF 160
>gi|111223123|ref|YP_713917.1| conserved hypothetical protein; putative HDIG domain [Frankia alni
ACN14a]
gi|111150655|emb|CAJ62356.1| conserved hypothetical protein; putative HDIG domain [Frankia alni
ACN14a]
Length = 207
Score = 91.3 bits (225), Expect = 2e-17, Method: Composition-based stats.
Identities = 55/137 (40%), Positives = 77/137 (56%), Gaps = 10/137 (7%)
Query: 50 VEEAAMLHDIGIF--LTDAESIACFGKEPYILHGYMGANILRKEGYPRHALVCER---HT 104
V A+LHDIG++ DA + Y+ HG +G +L +G P VC HT
Sbjct: 60 VRTGALLHDIGVYRLYDDAGQL---DHAQYLRHGVLGHELLAADGLPE--TVCRFASCHT 114
Query: 105 GSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSMLSYG 164
G GLT DIAA + LPPG Y Q++EE++V YADKF SK++ ++ R + +G
Sbjct: 115 GVGLTRADIAAGDLPLPPGDYLAQTVEERLVMYADKFHSKSRPTSFLTVDAYRGHVRRFG 174
Query: 165 ADSLRRFDEMHALFKIP 181
AD + RFDE+ A F +P
Sbjct: 175 ADKVARFDELTAEFGVP 191
>gi|23464811|ref|NP_695414.1| hypothetical protein BL0196 [Bifidobacterium longum NCC2705]
gi|23325391|gb|AAN24050.1| hypothetical protein BL0196 [Bifidobacterium longum NCC2705]
Length = 207
Score = 81.6 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 50/148 (33%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Query: 41 PELQADRLFVEEAAMLHDIGIFL------TDAESIACFGKEPYILHGYMGANILRKEGYP 94
P D V +LHDIG + +D E + F K+ YILHG G L EG
Sbjct: 47 PPRLLDEHLVLIGGLLHDIGTYRVFKHDGSDGEPLK-FSKKRYILHGLKGYEYLLDEGVD 105
Query: 95 RH-ALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKL 153
A C HTG GLT ED+ +++ LPP Y P ++E+++V YADKF SK+ + ++
Sbjct: 106 ESIAQFCRNHTGVGLTREDVVRQELPLPPADYVPMNLEQEVVMYADKFHSKSVPPKFLQV 165
Query: 154 EDVRRSMLSYGADSLRRFDEMHALFKIP 181
E +G ++ +R+ ++ A + +P
Sbjct: 166 EAYTARAERFGGENKQRWLDLVAKYGVP 193
>gi|23335965|ref|ZP_00121195.1| COG1418: Predicted HD superfamily hydrolase [Bifidobacterium longum
DJO10A]
Length = 234
Score = 81.3 bits (199), Expect = 2e-14, Method: Composition-based stats.
Identities = 50/148 (33%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Query: 41 PELQADRLFVEEAAMLHDIGIFL------TDAESIACFGKEPYILHGYMGANILRKEGYP 94
P D V +LHDIG + +D E + F K+ YILHG G L EG
Sbjct: 74 PPRLLDEHLVLIGGLLHDIGTYRVFKHDGSDGEPLK-FSKKRYILHGLKGYEYLLDEGVD 132
Query: 95 RH-ALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKL 153
A C HTG GLT ED+ +++ LPP Y P ++E+++V YADKF SK+ + ++
Sbjct: 133 ESIAQFCRNHTGVGLTREDVVRQELPLPPADYVPMNLEQEVVMYADKFHSKSVPPKFLQV 192
Query: 154 EDVRRSMLSYGADSLRRFDEMHALFKIP 181
E +G ++ +R+ ++ A + +P
Sbjct: 193 EAYTARAERFGGENKQRWLDLVAKYGVP 220
>gi|147921601|ref|YP_684582.1| hypothetical protein LRC275 [uncultured methanogenic archaeon RC-I]
gi|110619978|emb|CAJ35256.1| conserved hypothetical protein [uncultured methanogenic archaeon
RC-I]
Length = 217
Score = 79.7 bits (195), Expect = 7e-14, Method: Composition-based stats.
Identities = 55/145 (37%), Positives = 76/145 (52%), Gaps = 25/145 (17%)
Query: 1 MMDP---ISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLH 57
MM P ++++ KY T + ++EH + V A+ + H DR VE A+LH
Sbjct: 1 MMKPEEALALLKKYGTSDS-----VIEHVKAVRDYAMELAAQH---DCDRELVEAGALLH 52
Query: 58 DIGIFLTDAESIACFGKEPYILHGYMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAAR 116
DIG T + I H +GA ILR+EG + + ERH G+GLT ED A
Sbjct: 53 DIGRSRTHS-----------IDHAIIGAAILRQEGVDERIIRITERHIGAGLTDED--AV 99
Query: 117 QIALPPGIYTPQSIEEKIVCYADKF 141
+ LPPG Y P+++EEKIVC AD
Sbjct: 100 NLGLPPGDYLPKTMEEKIVCQADNL 124
>gi|13541902|ref|NP_111590.1| Predicted hydrolase (HD superfamily) [Thermoplasma volcanium GSS1]
gi|14325335|dbj|BAB60239.1| hypothetical protein [Thermoplasma volcanium GSS1]
Length = 338
Score = 78.6 bits (192), Expect = 1e-13, Method: Composition-based stats.
Identities = 59/174 (33%), Positives = 88/174 (50%), Gaps = 23/174 (13%)
Query: 12 YTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIAC 71
Y G + Y L+ H + V LA V I + AD V A+LHDIG T + I
Sbjct: 180 YKYGASDY--LINHVKSVKELA---VAIAKKTNADINLVTAGALLHDIG--RTQVQGIT- 231
Query: 72 FGKEPYILHGYMGANILRKEGYP-RHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSI 130
H +GA+ILR+EG R + E+H G+G+ SE+ A ++ LPP Y P++I
Sbjct: 232 --------HAVVGADILRREGIDDRVVSIVEKHIGAGIQSEE--AVKLGLPPDNYVPETI 281
Query: 131 EEKIVCYADKFFSKTK-LHRQKKLEDVRRSMLSYGADSLRRFDEMHALFKIPLG 183
EE IV +AD F+ K L Q+ +++ R+ L D+ R ++H +G
Sbjct: 282 EEMIVAHADNLFAGDKRLKLQQVVDNYRKKGLE---DAAERIAKLHKFLSTVIG 332
>gi|48477768|ref|YP_023474.1| metal dependent phosphohydrolase [Picrophilus torridus DSM 9790]
gi|48430416|gb|AAT43281.1| metal dependent phosphohydrolase [Picrophilus torridus DSM 9790]
Length = 341
Score = 73.9 bits (180), Expect = 4e-12, Method: Composition-based stats.
Identities = 50/140 (35%), Positives = 74/140 (52%), Gaps = 17/140 (12%)
Query: 17 NQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEP 76
N +++ H V +A+R+ + P DR V A+LHDIG T+
Sbjct: 182 NADDLIIRHVETVYKVAMRMADCIP---CDRRLVAAGALLHDIGRTKTNN---------- 228
Query: 77 YILHGYMGANILRKEGYP-RHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIV 135
I H GA IL+K+ R + ERHTG+G+TSE+ A+++ LP Y P++IEEKIV
Sbjct: 229 -IDHAIAGAEILKKKNIDDRIVRIVERHTGAGITSEE--AQKLGLPVKDYVPETIEEKIV 285
Query: 136 CYADKFFSKTKLHRQKKLED 155
+AD S ++ K+L D
Sbjct: 286 AHADNLVSMDRIINLKQLMD 305
>gi|148642692|ref|YP_001273205.1| predicted hydrolase, HD superfamily [Methanobrevibacter smithii
ATCC 35061]
gi|148551709|gb|ABQ86837.1| predicted hydrolase, HD superfamily [Methanobrevibacter smithii
ATCC 35061]
Length = 164
Score = 73.6 bits (179), Expect = 6e-12, Method: Composition-based stats.
Identities = 47/126 (37%), Positives = 70/126 (55%), Gaps = 16/126 (12%)
Query: 22 LVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILHG 81
++EHS+ V A++I + + AD+ +++ A+LHDIG T I H
Sbjct: 15 VIEHSKAVCKKAMKIADNFKD--ADKDLIKKGALLHDIGRSKTHG-----------ITHA 61
Query: 82 YMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
GA I+R+ GYP + ERH G+GL+ ++ A ++ LP Y PQ+IEEKIV +AD
Sbjct: 62 VEGAKIVREYGYPEEVQNIVERHIGAGLSEDE--AIKLGLPKKSYIPQTIEEKIVAHADN 119
Query: 141 FFSKTK 146
S TK
Sbjct: 120 LISGTK 125
>gi|15679662|ref|NP_276779.1| hypothetical protein MTH1668 [Methanothermobacter
thermautotrophicus str. Delta H]
gi|2622797|gb|AAB86140.1| conserved protein [Methanothermobacter thermautotrophicus str.
Delta H]
Length = 160
Score = 71.6 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 47/123 (38%), Positives = 65/123 (52%), Gaps = 17/123 (13%)
Query: 22 LVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILHG 81
+++HS V AL E+ EL D VEE A+LHDIG T + H
Sbjct: 15 VIDHSLAVRKKAL---ELSRELPVDMKLVEEGAILHDIGRCRTSG-----------VEHA 60
Query: 82 YMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
GA IL GYP + + ERH G+G+ E+ A+ + LPPG Y P+++EEKIV +AD
Sbjct: 61 VEGARILEGFGYPPEVVRIVERHVGAGIPPEE--AKALGLPPGDYMPRTLEEKIVAHADN 118
Query: 141 FFS 143
+
Sbjct: 119 LIN 121
>gi|16081979|ref|NP_394389.1| hypothetical protein Ta0931 [Thermoplasma acidophilum DSM 1728]
gi|10640246|emb|CAC12060.1| conserved hypothetical protein [Thermoplasma acidophilum]
Length = 339
Score = 70.5 bits (171), Expect = 4e-11, Method: Composition-based stats.
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 21/156 (13%)
Query: 22 LVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILHG 81
L+EH + V LAL+I E AD+ + ++LHDIG T+ I H
Sbjct: 188 LIEHVKAVEGLALKIAE---RCNADKRVIVAGSLLHDIGRTRTNG-----------IDHA 233
Query: 82 YMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
GA ILR E + ERH G+G+T E+ A ++ LP Y P+++EE IV AD
Sbjct: 234 VAGAEILRSENIHDSVVSAVERHIGAGITREEAA--RLGLPEKDYVPETLEEMIVAQADN 291
Query: 141 FFSKTKLHRQKKLEDVRRSMLSYGADS-LRRFDEMH 175
F+ K + +LE+V G DS R E+H
Sbjct: 292 LFAGNK---RLRLEEVLNIYRKRGLDSAAERIKELH 324
>gi|20093932|ref|NP_613779.1| Predicted HD superfamily hydrolase [Methanopyrus kandleri AV19]
gi|19886882|gb|AAM01709.1| Predicted HD superfamily hydrolase [Methanopyrus kandleri AV19]
Length = 173
Score = 68.9 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 54/157 (34%), Positives = 82/157 (52%), Gaps = 19/157 (12%)
Query: 22 LVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILHG 81
++EH + V LA + E E D V A+LHDIG T I H
Sbjct: 17 VIEHCKAVCRLAEEMAE-RCEEDVDLNLVRTGALLHDIGRARTHG-----------IDHA 64
Query: 82 YMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
+GANI+ + GYP+ + + ERH G+G+ ++ A+++ LPP Y P+++EEKIV +AD
Sbjct: 65 VVGANIVSELGYPKEVVRIVERHIGAGIPKDE--AKKLGLPPKDYIPETLEEKIVAHADN 122
Query: 141 FFSKTKLHRQKKLEDVRRSMLSYGADS--LRRFDEMH 175
T+ H K+ VR+ G DS ++R E+H
Sbjct: 123 LTFGTE-HVPIKVV-VRKFSERLGEDSPAVKRLIELH 157
>gi|15668959|ref|NP_247763.1| hypothetical protein MJ0778 [Methanocaldococcus jannaschii DSM
2661]
gi|2833583|sp|Q58188|Y778_METJA Uncharacterized protein MJ0778
gi|1499598|gb|AAB98768.1| conserved hypothetical protein [Methanocaldococcus jannaschii DSM
2661]
Length = 169
Score = 63.5 bits (153), Expect = 6e-09, Method: Composition-based stats.
Identities = 57/183 (31%), Positives = 90/183 (49%), Gaps = 28/183 (15%)
Query: 5 ISIINKYYTEGTNQYHILVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLT 64
+SI+ +E ++ + V ALA++ + + D V +LHDIG T
Sbjct: 7 LSILKNLCSENVVEHCLAVSEYAYELALAIK----NKGYEVDVELVRLGGLLHDIGRSRT 62
Query: 65 DAESIACFGKEPYILHGYMGANILRKEGY-PRHALVCERHTGSGLTSEDIAARQIALPPG 123
I HG +GA ILR+ G+ + AL+ ERH G+G+T E+ A ++ LPP
Sbjct: 63 HG-----------IEHGVVGAEILRELGFDEKLALIAERHIGAGITKEE--AIELGLPPK 109
Query: 124 IYTPQSIEEKIVCYADKFFSKTKLHRQKKLEDVRRSM---LSYGADSLRRF----DEMHA 176
Y P ++EEKIV +AD TK + +++DV + L S++R DE++
Sbjct: 110 DYLPITLEEKIVAHADNLIFGTK---RVEIDDVIKKFEKRLGKNHPSIKRIILLNDEINN 166
Query: 177 LFK 179
L K
Sbjct: 167 LLK 169
>gi|73667744|ref|YP_303759.1| metal-dependent phosphohydrolase [Methanosarcina barkeri str.
Fusaro]
gi|72394906|gb|AAZ69179.1| metal-dependent phosphohydrolase [Methanosarcina barkeri str.
Fusaro]
Length = 170
Score = 62.8 bits (151), Expect = 9e-09, Method: Composition-based stats.
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 29/147 (19%)
Query: 22 LVEHSRDVAALALRIVE--------IHPELQADRLFVEEAAMLHDIGIFLTDAESIACFG 73
++EH ++VA+LA+ I ++PEL VE A+LHD+G C
Sbjct: 20 VIEHCKEVASLAVEIANKAKAAGHNVNPEL------VEVGALLHDLG---------RC-- 62
Query: 74 KEPYILHGYMGANILRKEGY-PRHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEE 132
K I H G + R EG P + + +RH G+G+++E+ AR + LP Y P+S+EE
Sbjct: 63 KTHKIAHAVEGYRLARIEGIEPEISEIIKRHIGAGISTEE--ARSLGLPEDDYFPRSLEE 120
Query: 133 KIVCYADKFFSKT-KLHRQKKLEDVRR 158
KIV +AD T ++ K++E +R+
Sbjct: 121 KIVAHADNLVKGTRRITVAKRIELMRK 147
>gi|21226795|ref|NP_632717.1| hypothetical protein MM_0693 [Methanosarcina mazei Go1]
gi|20905091|gb|AAM30389.1| conserved protein [Methanosarcina mazei Go1]
Length = 170
Score = 62.8 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 48/145 (33%), Positives = 74/145 (51%), Gaps = 17/145 (11%)
Query: 22 LVEHSRDVAALALRIVEIHPEL--QADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYIL 79
++EH ++VA+LA+ I E + D VE A+LHD G T I
Sbjct: 20 VIEHCKEVASLAVEIAEKAKAAGKEVDLELVEAGALLHDAGRCRTHG-----------IA 68
Query: 80 HGYMGANILRKEGY-PRHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYA 138
H G + G P A + +RH G+G++ E+ A+++ LP Y P+S+EEKIV +A
Sbjct: 69 HAVEGFRLATSRGIEPEVAEIIKRHIGAGISKEE--AKELGLPEDDYFPRSLEEKIVAHA 126
Query: 139 DKFFSKTK-LHRQKKLEDVRRSMLS 162
D TK + Q +LE +R+ +S
Sbjct: 127 DNLVKGTKRITAQDRLELMRKKNVS 151
>gi|84490061|ref|YP_448293.1| hypothetical protein Msp_1273 [Methanosphaera stadtmanae DSM 3091]
gi|84373380|gb|ABC57650.1| conserved hypothetical protein [Methanosphaera stadtmanae DSM 3091]
Length = 164
Score = 61.2 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 41/127 (32%), Positives = 68/127 (53%), Gaps = 18/127 (14%)
Query: 22 LVEHSRDVAALALRIVEIHPEL-QADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILH 80
+++HS V R +I P D ++ AMLHD+G +T+ I H
Sbjct: 21 IIDHSTTVYE---RTKDITPHYDNIDLDLIKAGAMLHDVGRTVTND-----------IKH 66
Query: 81 GYMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYAD 139
Y+GA++LR+ + ERH G+G+++++ A+++ LPP Y PQ++EEKIV +AD
Sbjct: 67 AYLGADLLRQLNVDEKICKITERHIGAGISAKE--AQKLRLPPRNYIPQTLEEKIVAHAD 124
Query: 140 KFFSKTK 146
T+
Sbjct: 125 NLVHGTE 131
>gi|154489116|ref|ZP_02029965.1| hypothetical protein BIFADO_02430 [Bifidobacterium adolescentis
L2-32]
gi|154083253|gb|EDN82298.1| hypothetical protein BIFADO_02430 [Bifidobacterium adolescentis
L2-32]
Length = 276
Score = 61.2 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 41 PELQADRLFVEEAAMLHDIGIFL------TDAESIACFGKEPYILHGYMGANILRKEGYP 94
P D V +LHDIG + +D E + F Y+ HG G L EG
Sbjct: 115 PPWLIDEHLVVIGGLLHDIGTYFLLKQDGSDGEPLK-FDGPHYVQHGLKGYEYLLNEGVD 173
Query: 95 RH-ALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKL 153
A HTG GLT E + ++ + LPP Y P ++E+++V ADK+ SK+ +
Sbjct: 174 ESIAQFARNHTGVGLTRETVESQGLPLPPADYVPMNLEQEVVMVADKYNSKSIPPKFLTA 233
Query: 154 EDVRRSMLSYGADSLRRF 171
E R +G + R +
Sbjct: 234 EAYTRKAARFGESNKREW 251
>gi|119026538|ref|YP_910383.1| hypothetical protein BAD_1520 [Bifidobacterium adolescentis ATCC
15703]
gi|118766122|dbj|BAF40301.1| hypothetical protein [Bifidobacterium adolescentis ATCC 15703]
Length = 276
Score = 60.5 bits (145), Expect = 4e-08, Method: Composition-based stats.
Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 41 PELQADRLFVEEAAMLHDIGIFL------TDAESIACFGKEPYILHGYMGANILRKEGYP 94
P D V +LHDIG + +D E + F Y+ HG G L EG
Sbjct: 115 PPRLIDEHLVVIGGLLHDIGTYFLLKQDGSDGEPLK-FDGPHYVQHGLKGYEYLLNEGVD 173
Query: 95 RH-ALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTKLHRQKKL 153
A HTG GLT E + ++ + LPP Y P ++E+++V ADK+ SK+ +
Sbjct: 174 ESIAQFARNHTGVGLTRETVESQGLPLPPADYVPMNLEQEVVMVADKYNSKSIPPKFLTA 233
Query: 154 EDVRRSMLSYGADSLRRF 171
E R +G + R +
Sbjct: 234 EAYTRKAARFGESNKREW 251
>gi|150399782|ref|YP_001323549.1| metal dependent phosphohydrolase [Methanococcus vannielii SB]
gi|150012485|gb|ABR54937.1| metal dependent phosphohydrolase [Methanococcus vannielii SB]
Length = 194
Score = 59.7 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 14/95 (14%)
Query: 53 AAMLHDIGIFLTDAESIACFGKEPYILHGYMGANILRKEGY-PRHALVCERHTGSGLTSE 111
A+LHDIG K YI HG +GA ILRK + + A + ERH G+G++ E
Sbjct: 78 GALLHDIG-----------RSKSNYIDHGIVGAEILRKNNFNEKFAKIAERHIGAGISKE 126
Query: 112 DIAARQIALPPGIYTPQSIEEKIVCYADKFFSKTK 146
+ A + LP Y P++IEEK++ AD K
Sbjct: 127 E--AVDLNLPKIDYIPETIEEKVIANADNLIFNDK 159
>gi|20092668|ref|NP_618743.1| metal-dependent phosphohydrolase [Methanosarcina acetivorans C2A]
gi|19917952|gb|AAM07223.1| metal-dependent phosphohydrolase [Methanosarcina acetivorans C2A]
Length = 170
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 29/151 (19%)
Query: 22 LVEHSRDVAALALRIV--------EIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFG 73
++EH ++VA+LA+ I ++PEL VE A+LHD+G T
Sbjct: 20 VIEHCKEVASLAVEIAAKAKAAGNNVNPEL------VEIGALLHDLGRCRTHG------- 66
Query: 74 KEPYILHGYMGANILRKEGY-PRHALVCERHTGSGLTSEDIAARQIALPPGIYTPQSIEE 132
I H G + + +G P A + +RH G+G++ E+ A+++ LP Y P+ +EE
Sbjct: 67 ----ISHAVEGFKLAQSKGVEPEVAEIIKRHIGAGVSKEE--AKELGLPEDDYFPRRLEE 120
Query: 133 KIVCYADKFFSKTK-LHRQKKLEDVRRSMLS 162
KIV +AD TK + K+LE + + +S
Sbjct: 121 KIVAHADNLVKGTKRITINKRLELMNKRNIS 151
>gi|134046669|ref|YP_001098154.1| metal dependent phosphohydrolase [Methanococcus maripaludis C5]
gi|132664294|gb|ABO35940.1| metal dependent phosphohydrolase [Methanococcus maripaludis C5]
Length = 194
Score = 53.9 bits (128), Expect = 4e-06, Method: Composition-based stats.
Identities = 37/122 (30%), Positives = 60/122 (49%), Gaps = 24/122 (19%)
Query: 53 AAMLHDIGIFLTDAESIACFGKEPYILHGYMGANILRKEGY-PRHALVCERHTGSGLTSE 111
A+LHDIG K I HG +G+ IL K + ++A + ERH G+G++ +
Sbjct: 78 GAILHDIG-----------RSKSHSIDHGIIGSKILLKNKFNEKYAKIAERHIGAGISKK 126
Query: 112 DIAARQIALPPGIYTPQSIEEKIVCYADKFFSK----------TKLHRQKKLEDVRRSML 161
+ A+++ LP Y P+++EEK++ AD S K ++ LE V + L
Sbjct: 127 E--AKKLNLPEKDYIPETLEEKVIANADNLISGYLRVDIDFVINKFKKRTNLEVVNKVYL 184
Query: 162 SY 163
Y
Sbjct: 185 LY 186
>gi|150402958|ref|YP_001330252.1| metal dependent phosphohydrolase [Methanococcus maripaludis C7]
gi|150033988|gb|ABR66101.1| metal dependent phosphohydrolase [Methanococcus maripaludis C7]
Length = 194
Score = 53.1 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 14/92 (15%)
Query: 53 AAMLHDIGIFLTDAESIACFGKEPYILHGYMGANILRKEGYP-RHALVCERHTGSGLTSE 111
A+LHDIG T + I HG +G+ IL K + ++A + ERH G+G++
Sbjct: 78 GAILHDIGRSKTHS-----------IDHGIIGSEILLKNNFEEKYAKIAERHIGAGISKT 126
Query: 112 DIAARQIALPPGIYTPQSIEEKIVCYADKFFS 143
+ A+++ LP Y P+++EEK++ AD S
Sbjct: 127 E--AKELNLPEKDYVPETLEEKVIANADNLIS 156
>gi|126008887|ref|ZP_01709458.1| hypothetical protein Faci_03000565 [Ferroplasma acidarmanus fer1]
Length = 349
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 17/127 (13%)
Query: 22 LVEHSRDVAALALRIVEIHPELQADRLFVEEAAMLHDIGIFLTDAESIACFGKEPYILHG 81
++EH V LA+ I + A+ + A+LHDIG T+ I H
Sbjct: 190 IIEHVTTVYKLAMAIGKY---AGANMELIRAGALLHDIGRTKTNG-----------IGHA 235
Query: 82 YMGANILRKEGYPRHAL-VCERHTGSGLTSEDIAARQIALPPGIYTPQSIEEKIVCYADK 140
GA+ILR++ + + E+HTG+G+ ++ A+++ LP Y +++EEKIV AD
Sbjct: 236 VAGADILREKNIDEAIVRIVEKHTGAGILPDE--AKKLGLPDRNYIQETLEEKIVAQADN 293
Query: 141 FFSKTKL 147
S K+
Sbjct: 294 LVSGKKI 300
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.323 0.139 0.409
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 685,329,652
Number of Sequences: 5470121
Number of extensions: 27305404
Number of successful extensions: 58028
Number of sequences better than 1.0e-05: 46
Number of HSP's better than 0.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 57959
Number of HSP's gapped (non-prelim): 46
length of query: 183
length of database: 1,894,087,724
effective HSP length: 124
effective length of query: 59
effective length of database: 1,215,792,720
effective search space: 71731770480
effective search space used: 71731770480
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 125 (52.8 bits)