SEMINAR: Monday January 24 2000, 11:00 am Lister Hill Center (NIH BLdg 38A), 8th floor conference room Sean Turner, Ph.D., Department of Biology, Indiana University, a visitor of the NCBI taxonomy group, will present a talk on the molecular systematics of cyanobacteria. The abstract is appended below. Regards, Detlef Leipe NCBI taxonomy group Sean Turner: "Molecular systematics of cyanobacteria: problems and solutions" The systematics and taxonomy of cyanobacteria ("blue-green algae") have been unusually problematic due in large part to differences in methodologies between the Botanical Code, by which cyanobacteria have traditionally been classied, and the Bacteriological Code, by which some investigators argue they should be classified, as they are now recognized to be true bacteria. Over the past 20 years, efforts have been made by proponents of each method to find common ground in order to resolve differences between competing classification systems, and significant progress has been made toward this end. However, during the same period methods of molecular phylogenetic sequence analysis have also been applied to the problem, and while there is some agreement between the results of these studies and the emergent system based on more classical criteria, there are also areas of significant disagreement pertaining to inferred evolutionary relationships among cyanobacteria and their systematic classification. Results of phylogenetic sequence studies using ribosomal RNAs from cyanobacteria and photosynthetic plastids will be presented along with a discussion of potentially confounding phenomena that can result in misleading inferences based on these analyses. Methods to circumvent such effects will discussed and the results of their application to the sequence data will be presented.