Early afterdepolarization abolished by potassium channel opener in a patient with idiopathic long QT syndrome.

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Title:	Early afterdepolarization abolished by potassium channel opener in a patient with idiopathic long QT syndrome.
Author:	Sato, T : Hata, Y : Yamamoto, M : Morita, H : Mizuo, K : Yamanari, H : Saito, D : Ohe, T
Citation:	J-Cardiovasc-Electrophysiol. 1995 Apr; 6(4): 279-82
Abstract:	We describe a 17-year-old boy with idiopathic long QT syndrome and repeated syncopal episodes. Early afterdepolarization (EAD) in the monophasic action potential (MAP) was demonstrated in the posterior septum of the left ventricle. Injection of the potassium channel opener nicorandil decreased EAD and shortened MAP duration. The syncopal episodes due to ventricular fibrillation disappeared after administration of the potassium channel opener.
Review References:	None
Notes:	None
Language:	English
Publication Type:	Journal-Article
Keywords:	Anti Arrhythmia Agents therapeutic use : Long QT Syndrome drug therapy : Niacinamide analogs and derivatives : Potassium Channels drug effects : Syncope etiology
URL:	http://www.futuraco.com/jce.htm