National Institute on Aging
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Laboratory of Personality and Cognition
Recent Publications

  1. Bagby RM, Quilty LC, Segal ZV, McBride CC, Kennedy SH, Costa PT. Personality and differential treatment response in major depression: a randomized controlled trial comparing cognitive-behavioural therapy and pharmacotherapy. Can J Psychiatry. 2008;53(6):361-370.

  2. Beason-Held LL, Kraut MA, Resnick SM. I. Longitudinal changes in aging brain function. Neurobiol Aging. 2008;29(4):483-496.

  3. Beason-Held LL, Kraut MA, Resnick SM. II. Temporal patterns of longitudinal change in aging brain function. Neurobiol Aging. 2008;29(4):497-513.

  4. Beydoun MA, Beason-Held LL. Does hypertension interact with body weight to impact cognitive function in the elderly?: Emerging evidence. Am J Hypertens. 2008;21(6):603.

  5. Beydoun MA, Lhotsky A, Wang Y, Forno GD, An Y, Metter EJ, Ferrucci L, O'Brien R, Zonderman AB. Association of adiposity status and changes in early to mid-adulthood with incidence of Alzheimer's disease. Am J Epidemiol. 2008;168(10):1179-1189.

  6. Brummett BH, Siegler IC, Day RS, Costa PT. Personality as a predictor of dietary quality in spouses during midlife. Behav Med. 2008;34(1):5-10.

  7. Davatzikos C, Fan Y, Wu X, Shen D, Resnick SM. Detection of prodromal Alzheimer's disease via pattern classification of magnetic resonance imaging. Neurobiol Aging. 2008;29(4):514-523.

  8. Davatzikos C, Resnick SM, Wu X, Parmpi P, Clark CM. Individual patient diagnosis of AD and FTD via high-dimensional pattern classification of MRI. Neuroimage. 2008;41(4):1220-1227.

  9. Dotson VM, Kitner-Triolo M, Evans MK, Zonderman AB. Literacy-based normative data for low socioeconomic status African Americans. Clin Neuropsychol. 2008;22(6):989-1017.

  10. Dotson VM, Resnick SM, Zonderman AB. Differential association of concurrent, baseline, and average depressive symptoms with cognitive decline in older adults. Am J Geriatr Psychiatry. 2008;16(4):318-330.

  11. Fan Y, Resnick SM, Wu X, Davatzikos C. Structural and functional biomarkers of prodromal Alzheimer's disease: A high-dimensional pattern classification study. Neuroimage. 2008;41(2):277-285.

  12. Grober E, Hall CB, Lipton RB, Zonderman AB, Resnick SM, Kawas C. Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease. J Int Neuropsychol Soc. 2008;14(2):266-278.

  13. Iacono D, O'Brien R, Resnick SM, Zonderman AB, Pletnikova O, Rudow G, An Y, West MJ, Crain B, Troncoso JC. Neuronal hypertrophy in asymptomatic Alzheimer disease. J Neuropathol Exp Neurol. 2008;67(6):578-589.

  14. Ironson GH, O'Cleirigh C, Weiss A, Schneiderman N, Costa PT Jr. Personality and HIV disease progression: role of NEO-PI-R openness, extraversion, and profiles of engagement. Psychosom Med. 2008;70(2):245-253.

  15. Jarvik L, Larue A, Blacker D, Gatz M, Kawas C, McArdle JJ, Morris JC, Mortimer JA, Ringman JM, Ercoli L, Freimer N, Gokhman I, Manly JJ, Plassman BL, Rasgon N, Roberts JS, Sunderland T, Swan GE, Wolf PA, Zonderman AB. Children of persons with Alzheimer disease: what does the future hold? Alzheimer Dis Assoc Disord. 2008;22(1):6-20.

  16. Kraut MA, Beason-Held LL, Elkins WD, Resnick SM. The impact of magnetic resonance imaging-detected white matter hyperintensities on longitudinal changes in regional cerebral blood flow. J Cereb Blood Flow Metab. 2008;28(1):190-197.

  17. Lettre G, Sankaran VG, Bezerra MA, Araújo AS, Uda M, Sanna S, Cao A, Schlessinger D, Costa FF, Hirschhorn JN, Orkin SH. DNA polymorphisms at the BCL11A, HBS1L-MYB, and {beta}-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Proc Natl Acad Sci USA. 2008; 105(33):11869-11874.

  18. Lockenhoff CE, Costa PT Jr, Lane RD. Age differences in descriptions of emotional experiences in oneself and others. J Gerontol B Psychol Sci Soc Sci. 2008;63(2):P92-P99.

  19. Lockenhoff CE, Terracciano A, Bienvenu OJ, Patriciu NS, Nestadt G, McCrae RR, Eaton WW, Costa PT, Jr. Ethnicity, education, and the temporal stability of personality traits in the East Baltimore Epidemiologic Catchment Area study. J Res Pers. 2008;42(3):577-598.

  20. McCrae RR. A note on some measures of profile agreement. J Pers Assess. 2008;90(2):105-109.

  21. McCrae RR, Martin TA, Hrebickova M, Urbanek T, Boomsma DI, Willemsen G, Costa PT Jr. Personality trait similarity between spouses in four cultures. J Pers. 2008;76(5):1137-1164.

  22. McCrae RR, Yamagata S, Jang KL, Riemann R, Ando J, Ono Y, Angleitner A, Spinath FM. Substance and artifact in the higher-order factors of the Big Five. J Pers Soc Psychol. 2008;95(2):442-455.

  23. Nestadt G, Costa PT Jr, Hsu FC, Samuels J, Bienvenu OJ, Eaton WW. The relationship between the five-factor model and latent Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition personality disorder dimensions. Compr Psychiatry. 2008;49(1):98-105.

  24. Rice SC, Zonderman AB, Metter EJ, Najjar SS, Waldstein SR. Absence of relation between depressive symptoms and carotid intimal medial thickness in the Baltimore Longitudinal Study of Aging. Psychosom Med. 2008 Oct. [Epub ahead of print].

  25. Rudow G, O'Brien R, Savonenko AV, Resnick SM, Zonderman AB, Pletnikova O, Marsh L, Dawson TM, Crain BJ, West MJ, Troncoso JC. Morphometry of the human substantia nigra in ageing and Parkinson's disease. Acta Neuropathol. 2008;115(4):461-470.

  26. Sharov AA, Falco G, Piao Y, Poosala S, Becker KG, Zonderman AB, Longo DL, Schlessinger D, Ko MS. Effects of aging and calorie restriction on the global gene expression profiles of testis and ovary. BMC Biol. 2008;6(1):24.

  27. Sojkova J, Beason-Held L, Zhou Y, An Y, Kraut MA, Ye W, Ferrucci L, Mathis CA, Klunk WE, Wong DF, Resnick SM. Longitudinal cerebral blood flow and amyloid deposition: An emerging pattern? J Nucl Med. 2008;49(9):1465-1471.

  28. Szekely CA, Green RC, Breitner JC, Ostbye T, Beiser AS, Corrada MM, Dodge HH, Ganguli M, Kawas CH, Kuller LH, Psaty BM, Resnick SM, Wolf PA, Zonderman AB, Welsh-Bohmer KA, Zandi PP. No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. Neurology. 2008;70(24):2291-2298.

  29. Terracciano A, Lockenhoff CE, Crum RM, Bienvenu OJ, Costa PT Jr. Five-Factor Model personality profiles of drug users. BMC Psychiatry. 2008;8(1):22.

  30. Terracciano A, Lockenhoff CE, Zonderman AB, Ferrucci L, Costa PT Jr. Personality predictors of longevity: activity, emotional stability, and conscientiousness. Psychosom Med. 2008;70(6):621-627.

  31. Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, Maschio A, Scally M, Patriciu N, Chen WM, Distel MA, Slagboom EP, Boomsma DI, Villafuerte S, Sliwerska E, Burmeister M, Amin N, Janssens AC, van Duijn CM, Schlessinger D, Abecasis GR, Costa PT Jr. Genome-wide association scan for five major dimensions of personality. Mol Psychiatry. 2008 Oct. [Epub ahead of print].

  32. Troncoso JC, Zonderman AB, Resnick SM, Crain B, Pletnikova O, O'Brien RJ. Effect of infarcts on dementia in the Baltimore Longitudinal Study of Aging. Ann Neurol. 2008;64(2);168-176.

  33. Trzeciak AR, Barnes J, Ejiogu N, Foster K, Brant LJ, Zonderman AB, Evans MK. Age, sex, and race influence single-strand break repair capacity in a human population. Free Radic Biol Med. 2008;45(12):1631-1641.

  34. Waldstein SR, Rice SC, Thayer JF, Najjar SS, Scuteri A, Zonderman AB. Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore Longitudinal Study of Aging. Hypertension. 2008;51(1):99-104.

  35. Beason-Held LL, Moghekar A, Zonderman AB, Kraut MA, Resnick SM. Longitudinal changes in cerebral blood flow in the older hypertensive brain. Stroke. 2007;38(6):1766-1773.

  36. Bruni AC, Momeni P, Bernardi L, Tomaino C, Frangipane F, Elder J, Kawarai T, Sato C, Pradella S, Wakutani Y, Anfossi M, Gallo M, Geracitano S, Costanzo A, Smirne N, Curcio SA, Mirabelli M, Puccio G, Colao R, Maletta RG, Kertesz A, St George-Hyslop P, Hardy J, Rogaeva E. Heterogeneity within a large kindred with frontotemporal dementia: a novel progranulin mutation. Neurology. 2007;69(2):140-147.

  37. Costa PT Jr, Terracciano A, Uda M, Vacca L, Mameli C, Pilia G, Zonderman AB, Lakatta E, Schlessinger D, McCrae RR. Personality traits in Sardinia: testing founder population effects on trait means and variances. Behav Genet. 2007;37(2):376-387.

  38. Driscoll I, Resnick SM. Testosterone and cognition in normal aging and Alzheimer's disease: an update. Curr Alzheimer Res. 2007;4(1):33-45.

  39. Isaacowitz DM, Lockenhoff CE, Lane RD, Wright R, Sechrest L, Riedel R, Costa PT. Age differences in recognition of emotion in lexical stimuli and facial expressions. Psychol Aging. 2007;22(1):147-159.

  40. Kraut MA, Beason-Held LL, Elkins WD, Resnick SM. The impact of magnetic resonance imaging-detected white matter hyperintensities on longitudinal changes in regional cerebral blood flow. J Cereb Blood Flow Metab. 2007 May; [Epub ahead of print].

  41. Lustig A, Weeraratna AT, Wood WW 3rd, Teichberg D, Bertak D, Carter A, Poosala S, Firman J, Becker KG, Zonderman AB, Longo DL, Taub DD. Transcriptome analysis of age-, gender- and diet-associated changes in murine thymus. Cell Immunol. 2007;245(1):42-61.

  42. Maki PM, Ernst M, London ED, Mordecai KL, Perschler P, Durso SC, Brandt J, Dobs A, Resnick SM. Intramuscular testosterone treatment in elderly men: evidence of memory decline and altered brain function. J Clin Endocrinol Metab. 2007;92(11):4107-4114.

  43. Moffat SD, Resnick SM. Long-term measures of free testosterone predict regional cerebral blood flow patterns in elderly men. Neurobiol Aging. 2007;28(6):914-920.

  44. Morgan MD, Mielke MM, O'Brien R, Troncoso JC, Zonderman AB, Lyketsos CG. Rates of depression in individuals with pathologic but not clinical Alzheimer disease are lower than those in individuals without the disease: findings from the Baltimore Longitudinal Study on Aging (BLSA). Alzheimer Dis Assoc Disord. 2007;21(3):199-204.

  45. Nguyen HT, Evans MK, Zonderman AB. Influence of medical conditions on executive and memory functions in low socioeconomic status African Americans. Arch Clin Neuropsychol. 2007;22(6):689-698.

  46. O'Cleirigh C, Ironson G, Weiss A, Costa PT Jr. Conscientiousness predicts disease progression (CD4 number and viral load) in people living with HIV. Health Psychol. 2007;26(4):473-480.

  47. Resnick SM, Driscoll I, Lamar M. Vulnerability of the orbitofrontal cortex to age-associated structural and functional brain changes. Ann NY Acad Sci. 2007;1121:562-575.

  48. Riudavets MA, Iacono D, Resnick SM, O'Brien R, Zonderman AB, Martin LJ, Rudow G, Pletnikova O, Troncoso JC. Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons. Neurobiol Aging. 2007;28(10):1484-1492.

  49. Ryder AG, Costa PT, Bagby RM. Evaluation of the SCID-II personality disorder traits for DSM-IV: coherence, discrimination, relations with general personality traits, and functional impairment. J Personal Disord. 2007;21(6):626-637.

  50. Xu X, Zhan M, Duan W, Prabhu V, Brenneman R, Wood W, Firman J, Li H, Zhang P, Ibe C, Zonderman AB, Longo DL, Poosala S, Becker KG, Mattson MP. Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender. Genome Biol. 2007 Nov.;8(11):R234 [Epub ahead of print].

  51. Zahn JM, Poosala S, Owen AB, Ingram DK, Lustig A, Carter A, Weeraratna AT, Taub DD, Gorospe M, Mazan-Mamczarz K, Lakatta EG, Boheler KR, Xu X, Mattson MP, Falco G, Ko MS, Schlessinger D, Firman J, Kummerfeld SK, Wood WH, Zonderman AB, Kim SK, Becker KG. AGEMAP: A Gene Expression Database for Aging in Mice. PLoS Genet. 2007;3(11):e201.

  52. Zhou Y, Resnick SM, Ye W, Fan H, Holt DP, Klunk WE, Mathis CA, Dannals R, Wong DF. Using a reference tissue model with spatial constraint to quantify [(11)C]Pittsburgh compound B PET for early diagnosis of Alzheimer's disease. Neuroimage. 2007;36(2):298-312.

  53. Brosschot JF, Gerin W, Thayer JF. The perseverative cognition hypothesis: A review of worry, prolonged stress-related physiological activation, and health. J Psychosom Res. 2006;60(2):113-124.

  54. Costa PT Jr, McCrae RR. Age changes in personality and their origins: comment on Roberts, Walton, and Viechtbauer. Psychol Bull. 2006;132(1):26-28.

  55. Davatzikos C, Fan Y, Wu X, Shen D, Resnick SM. Detection of prodromal Alzheimer's disease via pattern classification of MRI. Neurobiol Aging. 2006 Dec.; [Epub ahead of print].

  56. Driscoll I, Resnick SM, Troncoso JC, An Y, O'Brien R, Zonderman AB. Impact of Alzheimer's pathology on cognitive trajectories in nondemented elderly. Ann Neurol. 2006;60(6):688-695.

  57. Espeland MA, Coker LH, Wallace R, Rapp SR, Resnick SM, Limacher M, Powell LH, Messina CR. Association between alcohol intake and domain-specific cognitive function in older women. Neuroepidemiology. 2006;27(1):1-12.

  58. Gamaldo A, Moghekar A, Kilada S, Resnick SM, Zonderman AB, O'Brien R. Effect of a clinical stroke on the risk of dementia in a prospective cohort. Neurology. 2006;67(8):1363-1369.

  59. Irwin MR, Valladares EM, Motivala S, Thayer JF, Ehlers CL. Association between nocturnal vagal tone and sleep depth, sleep quality, and fatigue in alcohol dependence. Psychosom Med. 2006;68(1):159-166.

  60. Matthews G, Emo AK, Funke G, Zeidner M, Roberts RD, Costa PT Jr, Schulze R. Emotional intelligence, personality, and task-induced stress. J Exp Psychol Appl. 2006;12(2):96-107.

  61. Moffat SD, Resnick SM. Long-term measures of free testosterone predict regional cerebral blood flow patterns in elderly men. Neurobiol Aging. 2006 May; [Epub ahead of print].

  62. Nestadt G, Hsu FC, Samuels J, Bienvenu OJ, Reti I, Costa PT Jr, Eaton WW. Latent structure of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition personality disorder criteria. Compr Psychiatry. 2006;47(1):54-62.

  63. Nguyen HT, Zonderman AB. Relationship between age and aspects of depression: consistency and reliability across two longitudinal studies. Psychol Aging. 2006;21(1):119-126.

  64. Pilia G, Chen WM, Scuteri A, Orru M, Albai G, Dei M, Lai S, Usala G, Lai M, Loi P, Mameli C, Vacca L, Deiana M, Olla N, Masala M, Cao A, Najjar SS, Terracciano A, Nedorezov T, Sharov A, Zonderman AB, Abecasis GR, Costa P, Lakatta E, Schlessinger D. Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet. 2006;2(8).

  65. Resnick SM, Maki PM, Rapp SR, Espeland MA, Brunner R, Coker LH, Granek IA, Hogan P, Ockene JK, Shumaker SA. Effects of combination Estrogen plus Progestin hormone treatment on cognition and affect. J Clin Endocrinol Metab. 2006;91(5):1802-1810.

  66. Terracciano A, Costa PT Jr, McCrae RR. Personality plasticity after age 30. Pers Soc Psychol Bull. 2006;32(8):999-1009.

  67. Terracciano A, McCrae RR, Costa PT Jr. Longitudinal trajectories in Guilford-Zimmerman temperament survey data: results from the Baltimore Longitudinal Study of Aging. J Gerontol B Psychol Sci Soc Sci. 2006;61(2):P108-P116.

  68. Tosun D, Rettmann ME, Naiman DQ, Resnick SM, Kraut MA, Prince JL. Cortical reconstruction using implicit surface evolution: Accuracy and precision analysis. Neuroimage. 2006;29(3):838-852.

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Updated: Thursday January 15, 2009