Compton WM, Cotter LB, Ben-Abdallah A, Cunningham-Williams RM; International Conference on AIDS.

Int Conf AIDS. 1998; 12: 1069 (abstract no. 60380).

Washington University/Dept Psychiatry, St. Louis, MO 63108, USA.

OBJECTIVE: To compare the effectiveness of the NIDA standard HIV testing and counseling protocol to a four session, peer-delivered educational intervention among drug abusers with psychiatric comorbidity who are at high risk for becoming exposed to HIV. DESIGN: Randomized, controlled, 3-month follow-up study. METHODS: In this randomized, NIDA-funded (Grant DA08324) HIV prevention study, 897 out-of-treatment injection drug (IDU) or crack cocaine using subjects have completed the three month follow-up so far. Psychiatric diagnoses of antisocial personality disorder (ASPD) and depression were based on the Diagnostic Interview Schedule, Version III-R administered at baseline. HIV risk behaviors were assessed with the NIDA Risk Behavior Assessment administered at baseline and at the three month follow-up. RESULTS: We found significant improvement for both intervention groups in: crack cocaine use and number of drug injections, number of IDU sex partners and overall sex partners, but not condom use. In addition, subjects in the peer-delivered intervention improved more than the standard on crack cocaine use (84% vs. 78%, p < .05). We are now focusing on the effects of antisocial personality disorder (ASPD) and major depression on the prevention interventions because these disorders have been associated with higher than expected rates of HIV risk behaviors. For subjects with ASPD, the peer-delivered intervention is significantly (p < .05) more effective than the standard in reducing the number of IDU sex partners. Depression is not associated with differential intervention outcome. CONCLUSION: If these preliminary results are confirmed by further analyses on the complete sample, we conclude that ASPD should be considered when evaluating the results of HIV prevention studies because persons with ASPD need more intensive intervention that those without ASPD.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• Antisocial Personality Disorder
• Cocaine-Related Disorders
• Comorbidity
• Counseling
• Crack Cocaine
• Follow-Up Studies
• HIV Infections
• HIV Seropositivity
• Mental Disorders
• Peer Group
• Safe Sex
• Sexual Partners
• Substance-Related Disorders
• methods
• prevention & control
• therapy

Other ID:

• 98408629

UI: 102232331

From Meeting Abstracts