Mandibular osteomas in sporadic colorectal carcinoma. A genetic marker.

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Title:	Mandibular osteomas in sporadic colorectal carcinoma. A genetic marker.
Author:	Sondergaard, J O : Rasmussen, M S : Videbaek, H : Bernstein, I T : Myrhoj, T : Kristiansen, V B : Sommer, P : Bulow, S
Citation:	Scand-J-Gastroenterol. 1993 Jan; 28(1): 23-4
Abstract:	Pantomography of the mandible was performed in 98 patients with sporadic colorectal adenocarcinoma. Twenty-eight patients (29%) had osteomas versus 5% in a control group (P less than 0.001). Mandibular osteomas are found in most patients with the premalignant dominant syndrome familial adenomatous polyposis. Sporadic colorectal cancer examinations of married couples have shown that diet has only a moderate influence on the development of colorectal cancer, whereas pedigree studies indicate a genetic component. On this basis we conclude that mandibular osteomas are probably genetic markers of the development of sporadic colorectal carcinoma.
Review References:	None
Notes:	None
Language:	English
Publication Type:	Journal-Article
Keywords:	Adenocarcinoma genetics : Colorectal Neoplasms genetics : Mandibular Neoplasms genetics : Neoplasms, Multiple Primary genetics : Osteoma genetics
URL:	http://www.scup.no/journals/en/j-304.htm