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Clinical Trials in TMD Sections
Author Bio
Introduction
The Biopsychosocial Model
Designing Multicenter RCTs
Players in an RCT
Randomization
Trial Design Quality
Currently selected section: TMD Case Definition
Endpoints and Outcome Measures
Blinding & Masking
Study Sample Size
Number and Nature of Interventions
Study Length and Follow up
Intent-to-treat Analyses and Sample Size
Compliance
Multicenter RCTs
Implementing RCTs: Practical Issues
Analysis of TMD Trials
Conclusions
Acknowledgments
Appendix A
Appendix B

 

Chapter 22: Clinical Trials in Temporomandibular: TMD Case Definition
          

Mandibular Dysfunction

Limitation in ability to use the jaw without pain or discomfort is a common clinical presentation and restoration of adequate and comfortable jaw function is an objective for much of clinical TMD treatment. For purposes of defining potential TMD cases to receive clinical interventions in an RCT, the major manifestations of mandibular dysfunction are:

  • Limitations in range of motion--inability to open the mouth or to move the jaw laterally without pain; measured in mm.

  • Locking or catching of the jaw so that it remains in relatively fixed open or closed positions; assessed by history or clinical examination finding

  • Inability to use the jaws for normal functions such as chewing hard or soft foods, talking, smiling and even maintaining typical facial appearance; assessed by mandibular dysfunction scale scores (Stetenga et al., 1993).

Certain aspects of mandibular dysfunction can be operationally defined with relative objective measures, such as vertical range of motion, measured as millimeters, when the jaw is opened, without assistance, either with or without pain, or when the clinician assists the mandible to a maximum assisted opening position.

Question 7.1

The subjective report of pain is known to influence mandibular vertical range of motion, which is measured objectively using a millimeter ruler. Which of the following best describes how you would classify vertical range of jaw motion:

Selection AAs a clear objective sign of restricted mandibular function
Selection BAs a clear symptom of pain influencing mandibular movement
Selection CFor certain measurements more usefully viewed as a subjective symptom than as an objective sign of mandibular function
Selection DFor certain measurements more usefully viewed as an objective sign than as a subjective symptom of mandibular function


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