LOCUS       NP_996258                249 aa            linear   ROD 08-JUN-2008
DEFINITION  Cd200 receptor 2 [Mus musculus].
ACCESSION   NP_996258 XP_195003
VERSION     NP_996258.1  GI:45504373
DBSOURCE    REFSEQ: accession NM_206535.1
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
REFERENCE   1  (residues 1 to 249)
  AUTHORS   Gorczynski,R., Khatri,I., Lee,L. and Boudakov,I.
  TITLE     An interaction between CD200 and monoclonal antibody agonists to
            CD200R2 in development of dendritic cells that preferentially
            induce populations of CD4+CD25+ T regulatory cells
  JOURNAL   J. Immunol. 180 (9), 5946-5955 (2008)
   PUBMED   18424714
  REMARK    GeneRIF: An interaction between CD200 and monoclonal antibody
            agonists to CD200R2 in development of dendritic cells that
            preferentially induce populations of CD4+CD25+ T regulatory cells.
REFERENCE   2  (residues 1 to 249)
  AUTHORS   Hatherley,D., Cherwinski,H.M., Moshref,M. and Barclay,A.N.
  TITLE     Recombinant CD200 protein does not bind activating proteins closely
            related to CD200 receptor
  JOURNAL   J. Immunol. 175 (4), 2469-2474 (2005)
   PUBMED   16081818
  REMARK    GeneRIF: The CD200 receptor family consists of both activatory and
            inhibitory members, like several other paired ligand receptors.
REFERENCE   3  (residues 1 to 249)
  AUTHORS   Gorczynski,R.M., Chen,Z., Clark,D.A., Kai,Y., Lee,L., Nachman,J.,
            Wong,S. and Marsden,P.
  TITLE     Structural and functional heterogeneity in the CD200R family of
            immunoregulatory molecules and their expression at the
            feto-maternal interface
  JOURNAL   Am. J. Reprod. Immunol. 52 (2), 147-163 (2004)
   PUBMED   15274657
REFERENCE   4  (residues 1 to 249)
  AUTHORS   Gorczynski,R., Chen,Z., Kai,Y., Lee,L., Wong,S. and Marsden,P.A.
  TITLE     CD200 is a ligand for all members of the CD200R family of
            immunoregulatory molecules
  JOURNAL   J. Immunol. 172 (12), 7744-7749 (2004)
   PUBMED   15187158
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY230198.1.
            On Mar 22, 2004 this sequence version replaced gi:38079800.
FEATURES             Location/Qualifiers
     source          1..249
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16B5"
     Protein         1..249
                     /product="Cd200 receptor 2"
                     /note="CD200 cell surface glycoprotein receptor"
                     /calculated_mol_wt=27277
     Region          26..126
                     /region_name="V-set"
                     /note="Immunoglobulin V-set domain; pfam07686"
                     /db_xref="CDD:116300"
     Region          136..202
                     /region_name="IG"
                     /note="Immunoglobulin domain family; members are
                     components of immunoglobulins, neuroglia, cell surface
                     glycoproteins, such as, T-cell receptors, CD2, CD4, CD8,
                     and membrane glycoproteins, such as, butyrophilin and
                     chondroitin sulfate proteoglycan core...; cl00093"
                     /db_xref="CDD:119524"
     CDS             1..249
                     /gene="Cd200r2"
                     /gene_synonym="AY230198"
                     /coded_by="NM_206535.1:214..963"
                     /db_xref="CCDS:CCDS28191.1"
                     /db_xref="GeneID:271375"
                     /db_xref="MGI:3042847"
ORIGIN      
        1 mhalgrtpal tllifiynfv svytivsvqm gtkarlccrs ipltkavlit wiikprgqps
       61 cimaykvetk etnetclgrn itwastpdhi pdlqisaval qhegnylcei ttpegnfhkv
      121 ydlqvlvppe vtyflgenrt avceamagkp aaqiswtpdg dcvtkseshs ngtvtvrstc
      181 hweqnnvsav scivshstgn qslsielsrg ttsttpsllt ilyvkmvllg iillkvgfaf
      241 fqkrnvtrt
//