LOCUS NP_996258 249 aa linear ROD 08-JUN-2008
DEFINITION Cd200 receptor 2 [Mus musculus].
ACCESSION NP_996258 XP_195003
VERSION NP_996258.1 GI:45504373
DBSOURCE REFSEQ: accession NM_206535.1
KEYWORDS .
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
Sciurognathi; Muroidea; Muridae; Murinae; Mus.
REFERENCE 1 (residues 1 to 249)
AUTHORS Gorczynski,R., Khatri,I., Lee,L. and Boudakov,I.
TITLE An interaction between CD200 and monoclonal antibody agonists to
CD200R2 in development of dendritic cells that preferentially
induce populations of CD4+CD25+ T regulatory cells
JOURNAL J. Immunol. 180 (9), 5946-5955 (2008)
PUBMED 18424714
REMARK GeneRIF: An interaction between CD200 and monoclonal antibody
agonists to CD200R2 in development of dendritic cells that
preferentially induce populations of CD4+CD25+ T regulatory cells.
REFERENCE 2 (residues 1 to 249)
AUTHORS Hatherley,D., Cherwinski,H.M., Moshref,M. and Barclay,A.N.
TITLE Recombinant CD200 protein does not bind activating proteins closely
related to CD200 receptor
JOURNAL J. Immunol. 175 (4), 2469-2474 (2005)
PUBMED 16081818
REMARK GeneRIF: The CD200 receptor family consists of both activatory and
inhibitory members, like several other paired ligand receptors.
REFERENCE 3 (residues 1 to 249)
AUTHORS Gorczynski,R.M., Chen,Z., Clark,D.A., Kai,Y., Lee,L., Nachman,J.,
Wong,S. and Marsden,P.
TITLE Structural and functional heterogeneity in the CD200R family of
immunoregulatory molecules and their expression at the
feto-maternal interface
JOURNAL Am. J. Reprod. Immunol. 52 (2), 147-163 (2004)
PUBMED 15274657
REFERENCE 4 (residues 1 to 249)
AUTHORS Gorczynski,R., Chen,Z., Kai,Y., Lee,L., Wong,S. and Marsden,P.A.
TITLE CD200 is a ligand for all members of the CD200R family of
immunoregulatory molecules
JOURNAL J. Immunol. 172 (12), 7744-7749 (2004)
PUBMED 15187158
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AY230198.1.
On Mar 22, 2004 this sequence version replaced gi:38079800.
FEATURES Location/Qualifiers
source 1..249
/organism="Mus musculus"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="16"
/map="16B5"
Protein 1..249
/product="Cd200 receptor 2"
/note="CD200 cell surface glycoprotein receptor"
/calculated_mol_wt=27277
Region 26..126
/region_name="V-set"
/note="Immunoglobulin V-set domain; pfam07686"
/db_xref="CDD:116300"
Region 136..202
/region_name="IG"
/note="Immunoglobulin domain family; members are
components of immunoglobulins, neuroglia, cell surface
glycoproteins, such as, T-cell receptors, CD2, CD4, CD8,
and membrane glycoproteins, such as, butyrophilin and
chondroitin sulfate proteoglycan core...; cl00093"
/db_xref="CDD:119524"
CDS 1..249
/gene="Cd200r2"
/gene_synonym="AY230198"
/coded_by="NM_206535.1:214..963"
/db_xref="CCDS:CCDS28191.1"
/db_xref="GeneID:271375"
/db_xref="MGI:3042847"
ORIGIN
1 mhalgrtpal tllifiynfv svytivsvqm gtkarlccrs ipltkavlit wiikprgqps
61 cimaykvetk etnetclgrn itwastpdhi pdlqisaval qhegnylcei ttpegnfhkv
121 ydlqvlvppe vtyflgenrt avceamagkp aaqiswtpdg dcvtkseshs ngtvtvrstc
181 hweqnnvsav scivshstgn qslsielsrg ttsttpsllt ilyvkmvllg iillkvgfaf
241 fqkrnvtrt
//