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Low field encoding
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High field detection = better sensitivity
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APPLICATIONS:
Enhanced sensitivity expands the uses of nuclear magnetic
resonance (NMR) and magnetic resonance imaging (MRI)
to:
- Minute
sample quantities
- Low
concentrations
- Environments
not conducive to conventional NMR
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–––––––––
>
travel time:
~5 meters in ~ 15 seconds
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ADVANTAGES:
-
Conditions for encoding can be manipulated independently
from those for detection, optimizing both procedures
- Broadens
NMR/MRI applications by utilizing the myriad encoding features
of NMR while introducing alternative and sensitive detection
techniques
- Employs
non-penetrating detection methods
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ABSTRACT:
Berkeley
Lab's remote NMR/MRI detection invention allows for independent
manipulation of encoding and detection conditions so that
experimental and technical parameters can be adjusted to optimize
both processes.
Alexander Pines and colleagues have invented a technique that
allows the NMR/MRI signal of any gas or liquid having a long
polarization relaxation time to be prepared in one location
and detected in another. The signal can be remotely detected
by an array of ultrasensitive techniques so as to reconstruct
images and spectra yielding spatial distributions and molecular
compositions. The signal information can be encoded in the
longitudinal magnetization of 129xenon,
for example, which has been used extensively to characterize
surfaces and cavities in porous materials and biological systems.
This new Berkeley Lab method makes accessible spatial and
spectroscopic information about minute sample quantities or
samples encoded in very low magnetic fields. It includes optimized
rf coil detection and the possibility of using ultrasensitive
techniques like SQUIDs and optical devices in addition to
conventional NMR detection.
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STATUS:
- U.S. Patent Application #7,061,237. Available for licensing or collaborative research
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FOR
MORE INROMATION PLEASE SEE:
http://www.lbl.gov/Science-Articles/Archive/MSD-remote-detection-MRI.html
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REFERENCE
NUMBER: IB-1771
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SEE
THESE OTHER BERKELEY LAB TECHNOLOGIES IN THIS FIELD:
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