Selected Publications:

  • Diane J. Rodi, Suneeta Mandava, and Lee Makowski (2004) DIVAA Analysis of Amino Acid Diversity in Multiple Aligned Protein Sequences. Bioinformatics vol 20/3481-3489.request reprint

  • Mandava, S., Makowski, L., Devarapalli, S., Uzubell, J. and Rodi, D.J. (2004) RELIC A bioinformatics server for combinatorial peptide analysis and identification of protein-ligand interaction sites. Proteomics 2004, 4, 1439-1460.request reprint

  • R.F. Fischetti, D.J. Rodi, D.B. Gore and L. Makowski (2004) Wide Angle X-ray Solution Scattering As a Probe of Ligand-Induced Conformational Changes in Proteins. Chemistry and Biology vol 11, 1-20.request reprint

  • Rodi, D.J., Mandava, S. and Makowski, L. (2004) M13 bacteriophage structure and biology, In: Phage Display in Biotechnology and Drug Discovery (ed. Sachdev Sidhu), invited chapter, in press.

  • Fischetti RF, Rodi DJ, Mirza A, Irving TC, Kondrashkina E, Makowski L. (2003) High-resolution wide-angle X-ray scattering of protein solutions: effect of beam dose on protein integrity. J Synchrotron Radiat. 2003 Sep 1;10(Pt 5):398-404.request reprint

  • Makowski, L. and A. Soares (2003) Estimating the Diversity of Peptides Populations from Limited Sequence Data. Bioinformatics 19:483-489.request reprint

  • Makowski, L. and Rodi, D.J. (2003) Genome-wide characterization of the binding repertoire of small molecule drugs. Human Genomics 1:41-51.request reprint

  • Rodi, D.J., Soares, A. and Makowski, L. (2002) Quantitative Assessment of Peptide Sequence Diversity in M13 Combinatorial Peptide Phage Display Libraries. J. Mol. Biol. 322:1039.request reprint

  • Rodi, D.J., Agoston, G.E., Manon, R., Green, S.J. and Makowski, L. (2001) Identification of Small Molecule Binding Sites within Protein Sequences Using Phage Display Technology. Combinatorial Chemistry & High Throughput Screening, 4 (7), 553-572.request reprint

  • Rodi, D.J., Makowski, L. and Kay, B.K. (2001) One from Column A and Two from Column B: The Benefits of Phage-display in Molecular Recognition Studies. Current Opinion in Biol. And Chem. 6:92-96.request reprint

  • Mu XQ, Makowski L. (2000) The likelihood function in fiber diffraction. Acta Crystallogr A. 2000 Mar;56 (Pt 2):168-77.request reprint

  • Rodi DJ, Makowski L. (1999) Similarity between the sequences of taxol-selected peptides and the disordered loop of the anti-apoptotic protein, Bcl-2. Pac Symp Biocomput. 1999;:532-41.request reprint

  • Rodi DJ, Makowski L. (1999) Phage-display technology--finding a needle in a vast molecular haystack. Curr Opin Biotechnol. 1999 Feb;10(1):87-93. Review.request reprint

  • Rodi,D.J., Janes, R.W., Sanganee, H.J., Holton, R., Wallace, B.A. and Makowski, L. (1999) Screening a library of phage-displayed peptides identifies human Bcl-2 as a Taxol-binding protein. J. Mol. Biol. 285,197-204.request reprint

  • Makowski L. (1998) Don Caspar, TMV, and protein-protein interactions. Proteins. 1998 Feb 1;30(2):109-12.request reprint

  • Mu XQ, Makowski L, Magdoff-Fairchild B. (1998) Analysis of the stability of hemoglobin S double strands. Biophys J. 1998 Jan;74(1):655-68.request reprint

  • Cheng W, Bullitt E, Bhattacharyya L, Brewer CF, Makowski L. (1998) Electron microscopy and x-ray diffraction studies of Lotus tetragonolobus A isolectin cross-linked with a divalent Lewisx oligosaccharide, an oncofetal antigen. J Biol Chem. 1998 Dec 25;273(52):35016-22.request reprint

  • Bullitt E, Makowski L. (1998) Bacterial adhesion pili are heterologous assemblies of similar subunits. Biophys J. 1998 Jan;74(1):623-32.request reprint

  • Makowski L. (1998) An unreasonable man in a quasi-equivalent world. Biophys J. 1998 Jan;74(1):534-6.request reprint

  • Kishchenko G, Makowski L. (1997) Shuffling of structural elements in filamentous bacteriophages. Proteins. 1997 Mar;27(3):405-9.request reprint

  • Mu XQ, Makowski L, Fairchild BM. (1997) X-ray diffraction from a helix of any length that displays cumulative azimuthal disorder. Acta Crystallogr A. 1997 Jan 1;53 ( Pt 1):55-62.

  • Bullitt E, Jones CH, Striker R, Soto G, Jacob-Dubuisson F, Pinkner J, Wick MJ, Makowski L, Hultgren SJ. (1996) Development of pilus organelle subassemblies in vitro depends on chaperone uncapping of a beta zipper. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12890-5.request reprint

  • Bullitt E, Makowski L. (1995) Structural polymorphism of bacterial adhesion pili. Nature. 1995 Jan 12;373(6510):164-7.

  • Makowski L. (1995) Electron crystallography. Taxol found on tubulin. Nature. 1995 Jun 1;375(6530):361-2.

  • Kishchenko G, Batliwala H, Makowski L. (1994) Structure of a foreign peptide displayed on the surface of bacteriophage M13. J Mol Biol. 1994 Aug 12;241(2):208-13.

  • Makowski L. (1993) Structural constraints on the display of foreign peptides on filamentous bacteriophages. Gene. 1993 Jun 15;128(1):5-11. Review.

  • Specthrie L, Bullitt E, Horiuchi K, Model P, Russel M, Makowski L. (1992) Construction of a microphage variant of filamentous bacteriophage. J Mol Biol. 1992 Dec 5;228(3):720-4.

  • Bhattacharjee S, Glucksman MJ, Makowski L. (1992) Structural polymorphism correlated to surface charge in filamentous bacteriophages. Biophys J. 1992 Mar;61(3):725-35.

  • Gong M, Makowski L. (1992) Helical structure of P pili from Escherichia coli. Evidence from X-ray fiber diffraction and scanning transmission electron microscopy. J Mol Biol. 1992 Dec 5;228(3):735-42.

  • Glucksman MJ, Bhattacharjee S, Makowski L. (1992) Three-dimensional structure of a cloning vector. X-ray diffraction studies of filamentous bacteriophage M13 at 7 A resolution. J Mol Biol. 1992 Jul 20;226(2):455-70.

  • Makowski L. (1992) Terminating a macromolecular helix. Structural model for the minor proteins of bacteriophage M13. J Mol Biol. 1992 Dec 5;228(3):885-92.

  • Nambudripad R, Stark W, Makowski L. (1991) Neutron diffraction studies of the structure of filamentous bacteriophage Pf1. Demonstration that the coat protein consists of a pair of alpha-helices with an intervening, non-helical surface loop. J Mol Biol. 1991 Jul 20;220(2):359-79.

  • Nambudripad R, Stark W, Opella SJ, Makowski L. (1991) Membrane-mediated assembly of filamentous bacteriophage Pf1 coat protein. Science. 1991 May 31;252(5010):1305-8.

  • Stark W, Glucksman MJ, Makowski L. (1988) Conformation of the coat protein of filamentous bacteriophage Pf1 determined by neutron diffraction from magnetically oriented gels of specifically deuterated virions. J Mol Biol. 1988 Jan 5;199(1):171-82.

  • Weisel JW, Nagaswami C, Makowski L. (1987) Twisting of fibrin fibers limits their radial growth. Proc Natl Acad Sci U S A. 1987 Dec;84(24):8991-5.request reprint

  • Specthrie L, Greenberg J, Glucksman MJ, Diaz J, Makowski L. (1987) Structural responsiveness of filamentous bacteriophage Pf1: comparison of virion structure in fibers and solution. The effect of temperature and ionic strength. Biophys J. 1987 Aug;52(2):199-214.

  • Stubbs G, Namba K, Makowski L. (1986) Application of restrained least-squares refinement to fiber diffraction from macromolecular assemblies. Biophys J. 1986 Jan;49(1):58-60.

  • Glucksman MJ, Hay RD, Makowski L. (1986) X-ray diffraction from magnetically oriented solutions of macromolecular assemblies. Science. 1986 Mar 14;231(4743):1273-6.

  • Makowski L, Magdoff-Fairchild B. (1986) Polymorphism of sickle cell hemoglobin aggregates: structural basis for limited radial growth. Science. 1986 Dec 5;234(4781):1228-31.

  • Makowski L, Caspar DL, Phillips WC, Goodenough DA. (1984) Gap junction structures. V. Structural chemistry inferred from X-ray diffraction measurements on sucrose accessibility and trypsin susceptibility. J Mol Biol. 1984 Apr 15;174(3):449-81.

  • Castleman H, Specthrie L, Makowski L, Erlanger BF. (1984) Electronmicroscopy and circular dichroism of the dynamics of the formation and dissolution of supramolecular forms of Z-DNA. J Biomol Struct Dyn. 1984 Oct;2(2):271-83.

  • Makowski L, Caspar DL, Phillips WC, Baker TS, Goodenough DA. (1984) Gap junction structures. VI. Variation and conservation in connexon conformation and packing. Biophys J. 1984 Jan;45(1):208-18.

  • Caspar DL, Makowski L. (1981) The symmetries of filamentous phage particles. J Mol Biol. 1981 Jan 25;145(3):611-7.

  • Moody MF, Makowski L. (1981) X-ray diffraction study of tail-tubes from bacteriophage T2L. J Mol Biol. 1981 Aug 5;150(2):217-44.

  • Marvin D, Makowski L. (1980) Helical viruses. Prog Clin Biol Res. 1980;40:347-8.

  • Makowski L. (1980) Structural studies of the assembly of simple viruses. Prog Clin Biol Res. 1980;40:233-58. Review.

  • Makowski L, Caspar DL, Marvin DA. (1980) Filamentous bacteriophage Pf1 structure determined at 7A resolution by refinement of models for the alpha-helical subunit. J Mol Biol. 1980 Jun 25;140(2):149-81.

  • Makowski L, Caspar DL, Phillips WC, Goodenough DA. (1977) Gap junction structures. II. Analysis of the x-ray diffraction data. J Cell Biol. 1977 Aug;74(2):629-45.request reprint

  • Caspar DL, Goodenough DA, Makowski L, Phillips WC. (1977) Gap junction structures. I. Correlated electron microscopy and x-ray diffraction. J Cell Biol. 1977 Aug;74(2):605-28.request reprint

  • Makowski L. (1976) A physical basis for red cell membrane elasticity. J Theor Biol. 1976 Sep 7;61(1):27-45.

  • Makowski L. (1976) A phase transition model for hemolysis. J Theor Biol. 1976 Sep 7;61(1):47-53.

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