[Code of Federal Regulations] [Title 21, Volume 3] [Revised as of April 1, 2006] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR172.580] [Page 66] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 172_FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION--Table of Contents Subpart F_Flavoring Agents and Related Substances Sec. 172.580 Safrole-free extract of sassafras. The food additive safrole-free extract of sassafras may be safely used in accordance with the following prescribed conditions: (a) The additive is the aqueous extract obtained from the root bark of the plant Sassafras albidum (Nuttall) Nees (Fam. Lauraceae). (b) It is obtained by extracting the bark with dilute alcohol, first concentrating the alcoholic solution by vacuum distillation, then diluting the concentrate with water and discarding the oily fraction. (c) The purified aqueous extract is safrole-free. (d) It is used as a flavoring in food.