Bibliographic Citation
| Document | For copies of Journal Articles, please contact the Publisher or your local public or university library and refer to the information in the Resource Relation field. For copies of other documents, please see the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or Document Availability. |
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| Title | Evidence for homosexuality gene |
| Creator/Author | Pool, R. |
| Publication Date | 1993 Jul 16 |
| OSTI Identifier | OSTI ID: 5957271 |
| Other Number(s) | ISSN0036-8075; CODEN: SCIEAS |
| Resource Type | Journal Article |
| Resource Relation | Science (Washington, D.C.) ; Vol/Issue: 261:5119 |
| Subject | 550400 -- Genetics; BEHAVIOR-- GENES;HUMAN X CHROMOSOME-- GENETIC MAPPING;MALES-- BEHAVIOR;SEX-- GENES; BIOLOGICAL MARKERS |
| Related Subject | CHROMOSOMES;HETEROCHROMOSOMES;HUMAN CHROMOSOMES;MAPPING;X CHROMOSOME |
| Description/Abstract | A genetic analysis of 40 pairs of homosexual brothers has uncovered a region on the X chromosome that appears to contain a gene or genes for homosexuality.^When analyzing the pedigrees of homosexual males, the researcheres found evidence that the trait has a higher likelihood of being passed through maternal genes.^This led them to search the X chromosome for genes predisposing to homosexuality.^The researchers examined the X chromosomes of pairs of homosexual brothers for regions of DNA that most or all had in common.^Of the 40 sets of brothers, 33 shared a set of five markers in the q28 region of the long arm of the X chromosome.^The linkage has a LOD score of 4.0, which translates into a 99.5% certainty that there is a gene or genes in this area that predispose males to homosexuality.^The chief researcher warns, however, that this one site cannot explain all instances of homosexuality, since there were some cases where the trait seemed to be passed paternally.^And even among those brothers where there was no evidence that the trait was passed paternally, seven sets of brothers did not share the Xq28 markers.^It seems likely that homosexuality arises from a variety of causes. |
| Country of Publication | United States |
| Language | English |
| Format | Pages: 291-292 |
| System Entry Date | 2001 May 13 |
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Last Updated: 02/16/2009