Evidence that in vitro adherence of Klebsiella pneumoniae to ciliated hamster tracheal cells is mediated by type 1 fimbriae.

Infect Immun. 1988 November; 56(11): 3011–3013.

PMCID: PMC259688

R C Fader, K Gondesen, B Tolley, D G Ritchie, and P Moller

Shriners Burns Institute, University of Texas Medical Branch, Galveston 77550.

This article has been cited by other articles in PMC.

Abstract

Clinical isolates of fimbriated and nonfimbriated Klebsiella pneumoniae were examined for the ability to adhere to hamster tracheal cells cultured in vitro. Fimbriated-phase K. pneumoniae adhered preferentially to ciliated cells, whereas nonfimbriated-phase organisms were not adherent. The adherence was inhibited by D-mannose but not D-glucose, suggesting that type 1 fimbriae serve as the adhesin in the attachment process.

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Selected References

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