Zwahlen A, Guerra RL, Hadley WK, Tauber MG; International Conference on AIDS.
Int Conf AIDS. 1991 Jun 16-21; 7: 274 (abstract no. M.B.2368).
San Francisco General Hospital (SFGH), University of California, San Francisco, CA, USA
OBJECTIVE: HIV is a risk factor for bacteremic pneumococcal infection and H.i. pneumonia in adults. This study was designed to better define the association between HIV infection and H.i. bacteremia in a population of patients with a high prevalence of HIV infection and other chronic conditions that may predispose to H.i. bacteremia. METHODS: All episodes of H.i. bacteremia or meningitis were identified by review of microbiology records at SFGH from August 1986 to November 1990, and the medical records were reviewed to analyze the age, sex, HIV risk factors and antibody status, associated conditions, clinical presentation and outcome. RESULTS: Of the 48 patients with documented H.i. bacteremia, 31 were adults (24 males, 7 females, median age 38 yrs) and 17 children (9 males, 8 females, median age 10 mos). Sixteen (52%) of the 31 adult patients had documented HIV infection (AIDS 6, ARC 5, asymptomatic 1) or were at risk for HIV infection (4 cases). This group of patients, compared with the no known HIV risk group, had similar occurrence of heavy alcoholism (6/16 vs 8/15), smoking (6/16 vs 5/15), cirrhosis (2/16 vs 2/15), malignancy (2/16 vs 1/15) and fatal outcome (4/16 vs 4/15). The clinical presentation was pneumonia in 21 cases, sepsis in 5, meningitis, epiglottitis, pyelonephritis, tuboovarian abscess, and thrombophlebitis in 1 patient each. CONCLUSION: This study documents a substantial number of severe H.i. bacteremias in an adult population at high risk for HIV infection and other chronic conditions. The relevation of HIV infection as an independent risk factor for H.i. bacteremia should be further studied.
Publication Types:
Keywords:
- AIDS-Related Complex
- Acquired Immunodeficiency Syndrome
- Adult
- Bacteremia
- Child
- Female
- HIV Infections
- HIV Seropositivity
- Haemophilus Infections
- Haemophilus influenzae
- Humans
- Male
- Pneumococcal Infections
- Pneumonia
- Risk Factors
Other ID:
UI: 102183288
From Meeting Abstracts