Pathway Interaction Database homepage

About us

The Pathway Interaction Database is a highly-structured, curated collection of information about known biomolecular interactions and key cellular processes assembled into signaling pathways. It is a collaborative project between the US National Cancer Institute (NCI) and Nature Publishing Group (NPG), and is an open access online resource.

  • Carl F. Schaefer Project Co-Leader (NCI Center for Bioinformatics)
  • Jeffrey Buchoff Software Developer (NCI Center for Bioinformatics)
  • Timo Hannay Project Co-Leader (NPG)
  • Matthew Day Database Publisher (NPG)
  • Shiva Krupa Associate Editor (NPG)
  • Kira Anthony Assistant Editor (NPG)
About the National Cancer Institute

The National Cancer Institute is a component of the U.S. National Institutes of Health and is the Federal Government's principal agency for cancer research and training. Specifically, the NCI:

  • Supports and coordinates research projects conducted by universities, hospitals, research foundations, and businesses throughout the U.S.A and abroad through research grants and cooperative agreements.
  • Conducts research in its own laboratories and clinics.
  • Supports education and training in fundamental sciences and clinical disciplines for participation in basic and clinical research programs and treatment programs relating to cancer through career awards, training grants, and fellowships.
  • Supports research projects in cancer control.
  • Supports a national network of cancer centers.
  • Collaborates with voluntary organizations and other national and foreign institutions engaged in cancer research and training activities.
  • Encourages and coordinates cancer research by industrial concerns where such concerns evidence a particular capability for programmatic research.
  • Collects and disseminates information on cancer.
  • Supports construction of laboratories, clinics, and related facilities necessary for cancer research through the award of construction grants.

For more information, please visit www.cancer.gov.

About the Nature Publishing Group

Nature Publishing Group is the publisher of Nature, the international weekly journal of science, as well as over 60 other prestigious scientific journals.

In recent years, NPG's presence in the scientific community has been further enhanced by the launch of many new online resources that provide the scientific and medical communities with easy access to research results, news, events, and jobs information, together with features that facilitate communications and social interactions between scientists.

For more information, please visit npg.nature.com

Citing the Pathway Interaction Database

To cite the NCI-Nature Pathway Interaction Database please use the following format:

Carl F. Schaefer, Kira Anthony, Shiva Krupa, Jeffrey Buchoff, Matthew Day, Timo Hannay & Kenneth H. Buetow. PID: The Pathway Interaction Database. Nucleic Acids Research | doi:10.1093/nar/gkn653; published online October 2, 2008

Citing Pathways:

All predefined pathways have stable URLs that can be used for citation and linking purposes.

Pathway citation should include the title of the pathway, the name of the publication ("NCI-Nature Pathway Interaction Database"), and the URL. The following is an illustrative example:

Signaling events mediated by Stem cell factor receptor (c-Kit). NCI-Nature Pathway Interaction Database.
http://pid.nci.nih.gov/pathway_names?format=html&word=kitpathway

Citing Bioinformatics Primers:

Bioinformatics Primer citation should include the names of all authors, the title of the article, the name of the publication ("NCI-Nature Pathway Interaction Database"), the digital object identifier (DOI) and the year of publication in parentheses. The following is an illustrative example:

Matthews L, D'Eustachio P, Gillespie G, Croft D, de Bono B, Gopinath G, Jassal B, Lewis S, Schmidt E, Vastrik I, Wu G, Birney E & Stein L. An Introduction to the Reactome Knowledgebase of Human Biological Pathways and Processes. NCI-Nature Pathway Interaction Database. doi:10.1038/pid.2007.3 (2007).

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