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Br J Ophthalmol. 2001 September; 85(9): 1034–1037.
doi: 10.1136/bjo.85.9.1034.
PMCID: PMC1724105
Influence of glistenings on the optical quality of acrylic foldable intraocular lens
T. Oshika, Y. Shiokawa, S. Amano, and K. Mitomo
Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan. Email: oshika-tky/at/umin.ac.jp
Abstract
AIMS—To assess the influence of glistenings on the optical quality of acrylic foldable intraocular lens.
METHODS—Several degrees of glistenings in the optic were experimentally created by immersing the lens in water at 37°C for 48 hours and then at 25°C for 24 hours. Optical bench tests were carried out in water including measurements of spectral transmittance with the spectrophotometer, intensity of forward scattering using the integrating sphere photometer, modulation transfer function, and resolving power at various contrasts with and without the veiling glare light source.
RESULTS—Glistenings of 1+ to 4+ degrees were created, among which the 4+ glistenings seemed to be extremely intense and thought to be beyond the range of clinical settings. Clinically feasible level of glistenings, up to 3+, did not adversely influence spectral transmittance, scattering, modulation transfer function, and resolving power at various contrasts. The 4+ glistenings caused mild to moderate deteriorations of the optical quality of the lens.
CONCLUSION—The optical quality of the acrylic foldable intraocular lens is not significantly affected by the level of glistenings usually seen in the clinical setting.

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Selected References
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Figures and Tables
Figure 1  Figure 1  
Schematic drawing of integrating sphere photometer to measure forward scattering. (Left) The total amount of transmitted light was measured with the rear window closed. (Right) The amount of forward scattering was measured with the rear window open. (more ...)
Figure 2  Figure 2  
Optical bench apparatus to measure resolving power of the lens.
Figure 3  Figure 3  
Slit lamp photograph of glistenings ranging from 1+ to 4+.
Figure 4  Figure 4  
Spectral transmittance.
Figure 5  Figure 5  
Modulation transfer function.
Figure 6  Figure 6  
Resolving power at various contrasts without veiling glare light.
Figure 7  Figure 7  
Resolving power at various contrasts with veiling glare light on.
Figure 8  Figure 8  
Glare sensitivity index evaluated by three examiners. The line indicates the average.