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EC-NUMBER
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1.13.11.17
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ENZYME-NAME
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indole 2,3-dioxygenase
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ENZYME-SYSNAME
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The enzyme from the plant Jasminum grandiflorum is a flavoprotein containing copper, and forms anthranilate as the final product. One enzyme from Tecoma stans is also a flavoprotein containing copper and uses three atoms of oxygen per molecule of indole, to form anthranil (3,4-benzoisoxazol). A second enzyme from Tecoma stans, which is not a flavoprotein, uses four atoms of oxygen and forms anthranilate as the final product.
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ENZYME-CLASS
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Oxidoreductases Acting on single donors with incorporation of molecular oxygen (oxygenases) With incorporation of two atoms of oxygen
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SYNONYMS
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IDO (ambiguous);
indole 2,3-dioxygenase;;
indole oxidase;;
indole-oxygen 2,3-oxidoreductase (decyclizing);;
>>more synonyms
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REACTION
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indole + O2 = 2-formylaminobenzaldehyde [RN:R02338]
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PATHWAY
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EMP-PATHWAYS:
NO EMP PATHWAY FOUND
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KEGG-PATHWAYS:
Tryptophan metabolism;
>>more KEGG pathways
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GO_TERM
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GO:0047719:indole 2,3-dioxygenase activity
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ENZYME-COMMENT
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indole:oxygen 2,3-oxidoreductase (decyclizing)
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