National Toxicology Program

CASRN: 80-56-8

Formula: C10 H16

Synonyms/Common Names:

• ACITENE A
• CYCLIC DEXADIENE
• 2-PINENE
• 2,6,6-TRIMETHYLBICYCLO[3.1.1]HEPT-2-ENE

Known Uses:

SOLVENT FOR PROTECTIVE COATINGS, POLISHES, AND WAXES; SYNTHESIS OF CAMPHENE, CAMPHOR, TERPIN HYDRATE, TERPINEOL, SYNTHETIC PINE OIL, TERPINE ESTERS AND OTHERS; LUBE OIL ADDITIVES, FLAVORING ODORANT.

Nomination Background

Short-Term Toxicity

• 14-DAY (Inhalation)  (C20302) Completed 
  • TOX-81
    
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R&M: 0, 100, 200, 400, 800, OR 1600 PPM; 5/SEX/SPECIES/DOSE
• 13-WEEK (Inhalation) 
  • TOX-81
    
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R&M: 0, 25, 50, 100, 200, OR 400 PPM; R: 20/SEX/DOSE; M: 10/SEX/DOSE

Genetic Toxicology

• Micronucleus  (A82162) Completed 
  • Mice: B6C3F1
  • Male Negative 
  • Female Negative 
• Salmonella  (A29697) Completed 
  •  Negative