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Cadmium Cadmium
Health Effects

Hazards are present in every work environment; being unaware of them, especially when dealing with cadmium, can have critical, even fatal, consequences. Included among the references listed below are most of the major activities in which cadmium exposure may or has occurred. These links also aid in recognizing cadmium and cadmium compounds and the health effects associated with them.

Characteristics and Properties
  • Occupational Exposure to Cadmium. OSHA Preambles to Final Rules, (1992).
    • IV. Chemical Identification, Production, and Use of Cadmium. Identifies cadmium (Chemical Services Registry Number 7740-43-9) as a soft, blue-white malleable, lustrous metal or a grayish-white powder that is insoluble in water and reacts readily with dilute nitric acid. A primary use for cadmium metal is as an anticorrosive, electroplated onto steel. Cadmium may serve as an electrode component in alkaline batteries and may be used in alloys, silver solders, and welding.
  • Cadmium Compounds (as Cd). National Institute for Occupational Safety and Health (NIOSH) Immediately Dangerous to Life or Health Concentrations (IDHL) Documentation, (1996, August 16). Includes permissible exposure limit (PEL), IDLH, and acute toxicity data.
  • Toxicological Profile for Cadmium. Agency for Toxic Substances and Disease Register (ATSDR), (1999, July). Includes lists of the common synonyms, trade names, and other pertinent identification information for cadmium and its most important compounds. Lists important physical and chemical properties of cadmium and its most important compounds.
Hazard Recognition
  • Potential Hazards Associated With The Refurbishing of Gas Meters. OSHA Health Information Bulletin (HIB), (2001, December 21). Also available as a 26 KB PDF, 3 pages. Warns of potential cadmium dust exposure for employers and employees who repair or refurbish gas meters. Cleaning the threaded male gas inlet and outlet fitting on gas meters, called "ferrules" or "spuds", with high-speed rotating wire brushes may release cadmium dust. Employers at gas meter repair shops should determine whether meters being worked on are plated with cadmium and, if so, determine if workers are exposed.
  • Cadmium Overexposure in the Aircraft Repair Industry. OSHA Health Information Bulletin (HIB), (1989, February 21). Identifies a potential health hazard in the aircraft servicing, repairing, and maintenance industry resulting from exposure to cadmium dust. An inspection of an Eastern Airlines landing gear shop revealed employee exposures to 85 times the ceiling limit (0.5 mg/m(3)). Unventilated grinding activities to cadmium plated landing gear components were the cause.
  • Shipyard Employment. OSHA eTool.
  • Cadmium (Cd). US Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 84-116 (Current Intelligence Bulletin 42), (1984, September 27). Estimates that approximately 1,500,000 workers may be potentially exposed to cadmium, of which approximately 100,000 are identified with exposure to specific cadmium compounds or with industries that utilize cadmium (based on data from the National Occupational Hazard Survey). Sources of potential worker exposure to cadmium include ore smelting operations, mist from cadmium-containing electroplating baths, calcination (drying) of cadmium pigments, and handling of powdered cadmium oxide in production of cadmium soaps that are used to stabilize plastics.
  • Criteria for a Recommended Standard: Occupational Exposure to Cadmium. US Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 76-192, (1976, August). Proposes a recommended standard based on the health effects of exposure to cadmium.
  • Documentation for Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH) National Technical Information Service (NTIS) Publication No. PB-94-195047, (1994, May).
  • Documents the criteria and information sources that have been used by the National Institute for Occupational Safety and Health (NIOSH) to determine immediately dangerous to life or health concentrations (IDLHs), including cadmium.
  • Cadmium (Cd). National Institute for Occupational Safety and Health (NIOSH) Current Intelligence Bulletin 42, (1984, September 27). Recommends that cadmium and its compounds be regarded as potential occupational carcinogens and that appropriate controls be used to reduce worker exposure.
  • Cadmium hazards may be present in a number of seemingly unrelated operations and materials, such as paints, batteries, and phosphate fertilizers.
  • For additional information, see OSHA's Safety and Health Topics Pages on:
Health Effects
  • Occupational Exposure to Cadmium. OSHA Preambles to Final Rules, (1992).
    • V. Health Effects. Documents the adverse health effects from acute and chronic exposure to cadmium in both humans and animals.
      • Acute — Indicates that metal fume fever may result from acute exposure with flu-like symptoms of weakness, fever, headache, chills, sweating and muscular pain. Acute pulmonary edema usually develops within 24 hours and reaches a maximum by three days. If death from asphyxia does not occur, symptoms may resolve within a week.
      • Chronic — Identifies the most serious consequence of chronic cadmium poisoning is cancer (lung and prostate). The first observed chronic effect is generally kidney damage, manifested by excretion of excessive (low molecular weight) protein in the urine. Cadmium also is believed to cause pulmonary emphysema and bone disease (osteomalcia and osteoporosis). The latter has been observed in Japan ("itai-itai" disease) where residents were exposed to cadmium in rice crops irrigated with cadmium-contaminated water. Cadmium may also cause anemia, teeth discoloration (Cd forms CdS) and loss of smell (anosmia).
  • Cadmium (CAS No. 7440-43-9) and Cadmium Compounds. Report on Carcinogens (RoC). National Toxicology Program (NTP), US Department of Health and Human Services (DHHS), (2005, January 1), 149 KB PDF, 3 pages. Cadmium and cadmium compounds are known to be human carcinogens based on sufficient evidence of carcinogenicity in humans, including epidemiological and mechanistic information that indicate a causal relationship between exposure to cadmium and cadmium compounds and human cancer.
  • Cadmium compounds (as Cd). National Institute for Occupational Safety and Health (NIOSH). Immediately Dangerous to Life or Health Concentrations (IDLH) Documentation.
  • Worker Notification Program - Cadmium Recovery Workers (Cadmium). National Institute for Occupational Safety and Health (NIOSH), (2004, August 17). Includes sections on the following subjects: NIOSH Kidney Study, NIOSH Mortality Study, charts that show the risk of dying from lung cancer for cadmium workers at the plant, Steps to Protect Your Health, Estimated "Relative" Risk of Dying from Lung Cancer, and Additional Resources.
  • Thun MJ, Schnorr TM, et al. Mortality among a cohort of U.S. cadmium workers--an update. Journal of the National Cancer Institute. 1985 Feb;74(2): 325-33.
  • Cadmium Public Health Statement. Agency for Toxic Substances and Disease Register (ATSDR), 144 KB PDF, 13 pages. Discusses cadmium.
  • For additional information regarding the health effects of cadmium, see OSHA's Carcinogens Safety and Health Topics Page.

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Content Reviewed 07/12/2005
 
 


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