| Can J Comp Med. 1982 April; 46(2): 138–145. | PMCID: PMC1320268 |
The kinetics of mononuclear phagocytes in normal calves given Corynebacterium parvum. S A Al-Izzi, M G Maxie, V E Valli, B N Wilkie, and J A Johnson Abstract Two groups of calves, three in each group, were used to determine the kinetics of mononuclear phagocytes in normal calves and in calves given Corynebacterium parvum intravenously, using tritiated thymidine as an in vivo deoxyribonucleic acid label. In normal calves, the mean production time of labelled monocytes in the bone marrow was 36.4 +/- 2.04 hours. The turnover rate of labelled monocytes from the bone marrow into the peripheral blood was 5.4 +/- 0.3% per hour and the disappearance rate of labelled monocytes from the circulation was 0.9 +/- 0.3%. The half lives of labelled blood monocytes were 22.5 hours for cells with 16-30 grains and 19.5 hours for cells with 31-50 grains. Alveolar macrophages were derived from peripheral blood monocytes. In calves given C. parvum, the production time, turnover rate and half lives of labelled monocytes did not differ significantly (p greater than 0.05) from the values in normal calves. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.4M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. Images in this article Click on the image to see a larger version. These references are in PubMed. This may not be the complete list of references from this article. - Al-Izzi, SA; Maxie, MG; Valli, VE. Morphology and cytochemistry of bovine bone marrow mononuclear phagocytes. Can J Comp Med. 1982 Apr;46(2):130–132. [PubMed]
- van oud Alblas, AB; van Furth, R. Origin, Kinetics, and characteristics of pulmonary macrophages in the normal steady state. J Exp Med. 1979 Jun 1;149(6):1504–1518. [PubMed]
- Bowden, DH; Adamson, IY. Adaptive responses of the pulmonary macrophagic system to carbon. I. Kinetic studies. Lab Invest. 1978 Apr;38(4):422–429. [PubMed]
- Bowden, DH; Davies, E; Wyatt, JP. Cytodynamics of pulmonary alveolar cells in the mouse. Arch Pathol. 1968 Dec;86(6):667–670. [PubMed]
- Bursuker, I; Goldman, R. Quantitative and functional differences induced in bone marrow-derived mononuclear phagocytes by inflammatory stimuli. J Reticuloendothel Soc. 1979 May;25(5):533–544. [PubMed]
- Diesselhoff-den Dulk, MM; Crofton, RW; van Furth, R. Origin and kinetics of Kupffer cells during an acute inflammatory response. Immunology. 1979 May;37(1):7–14. [PubMed]
- Goud, TJ; Schotte, C; van Furth, R. Identification and characterization of the monoblast in mononuclear phagocyte colonies grown in vitro. J Exp Med. 1975 Nov 1;142(5):1180–1199. [PubMed]
- Goud, TJ; van Furth, R. Proliferative characteristics of monoblasts grown in vitro. J Exp Med. 1975 Nov 1;142(5):1200–1217. [PubMed]
- Markham, RJ; Wilkie, BN. Interaction between Pasteurella haemolytica and bovine alveolar macrophages: cytotoxic effect on macrophages and impaired phagocytosis. Am J Vet Res. 1980 Jan;41(1):18–22. [PubMed]
- Meuret, G; Bammert, J; Hoffmann, G. Kinetics of human monocytopoiesis. Blood. 1974 Dec;44(6):801–816. [PubMed]
- Meuret, G; Batara, E; Fürste, HO. Monocytopoiesis in normal man: pool size, proliferation activity and DNA synthesis time of promonocytes. Acta Haematol. 1975;54(5):261–270. [PubMed]
- Valli, VE; Hulland, TJ; McSherry, BJ; Robinson, GA; Gilman, JP. The kinetics of haematopoiesis in the calf. I. An autoradiographical study of myelopoiesis in normal, anaemic and endotoxin treated calves. Res Vet Sci. 1971 Nov;12(6):535–550. [PubMed]
- van Furth, R; Cohn, ZA. The origin and kinetics of mononuclear phagocytes. J Exp Med. 1968 Sep 1;128(3):415–435. [PubMed]
- van Furth, R; Diesselhoff-Den Dulk, MM. The kinetics of promonocytes and monocytes in the bone marrow. J Exp Med. 1970 Oct 1;132(4):813–828. [PubMed]
- Van Furth, R; Diesselhoff-den Dulk, MC; Mattie, H. Quantitative study on the production and kinetics of mononuclear phagocytes during an acute inflammatory reaction. J Exp Med. 1973 Dec 1;138(6):1314–1330. [PubMed]
- Walker, JM; Valli, VE; Lumsden, JH. Colony formation in culture by bovine granulopoietic progenitor cells. Can J Comp Med. 1974 Apr;38(2):145–152. [PubMed]
- Whitelaw, DM. The intravascular lifespan of monocytes. Blood. 1966 Sep;28(3):455–464. [PubMed]
- Whitelaw, DM. Observations on human monocyte kinetics after pulse labeling. Cell Tissue Kinet. 1972 Jul;5(4):311–317. [PubMed]
- Whitelaw, DM; Bell, MF; Batho, HF. Monocyte kinetics: observations after pulse labeling. J Cell Physiol. 1968 Aug;72(1):65–71. [PubMed]
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