Laperriere A, Ironson G, Antoni M, Klimas N, Schneiderman N, Fletcher MA; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 805 (abstract no. D.681).
University of Miami, Miami, FL, USA
OBJECTIVE: Receiving a positive test for the anti-human immunodeficiency virus (HIV-1) has been associated with increases in anxiety and depression. This could lead to a further suppression of an already compromised immune system resulting in an increased risk of opportunistic infection and a worsening of disease prognosis. METHOD: Forty-six healthy gay males, never tested and therefore not knowing their HIV-1 status, were randomly assigned to either an exercise intervention (N=28) or control (N=18) group. HIV-1 antibody status was determined at week 5 and subjects received their diagnosis 72 hrs later. The Profile of Mood States (POMS) was administered at baseline, week 5, 7, 8, and 10, while an aerobic fitness evaluation was conducted at baseline, week 5 and 10. The intervention, consisting of 45 min of aerobic exercise training 3 times per week for a 10 week period, resulted in a significant improvement in fitness levels in both anti-HIV-1 (-) and (+) subjects after 5 weeks. RESULTS: Anti-HIV-1 (+) controls displayed a significant increase in Tension-Anxiety (10.7 to 18.2, t[1,6]=18.75, p less than .01), Depression (9.3 to 26.8, t[1,6]=2.6, p less than .05) and Confusion-Bewilderment (5.3 to 11.8, t[1,6]=6.2, p less than .05) scales of the POMS in response to their diagnosis (week 5 to week 7). Conversely, anti-HIV-1(+) exercisers did not show such changes in the Tension-Anxiety (11.8 to 12.6, t[1,11]=.37, p greater than .05), Depression (10.4 to 14.0, t[1,11]=.58, p greater than .05), and Confusion-Bewilderment (7.2 to 8.7, t[1,11]=.70, p greater than .05) POMS scales over the same period. CONCLUSION: These findings indicate that a training program of modest aerobic exercise buffers the detrimental mood changes that accompany receiving news of anti-HIV-1(+) test, thus providing a promising behavioral approach to helping those infected with HIV-1. Supported by NIMH, P50MH42455-03.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Affect
- Anxiety
- Depression
- Exercise
- Exercise Therapy
- HIV Infections
- HIV-1
- Homosexuality, Male
- Humans
- Male
- Physical Education and Training
- Research Design
- Stress
- Stress, Psychological
- education
- rehabilitation
Other ID:
UI: 102180152
From Meeting Abstracts