BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= TDE1279
(766 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42526788|ref|NP_971886.1| phosphoribosylformylglycinamid... 1541 0.0
gi|76258610|ref|ZP_00766264.1| Phosphoribosylformylglycinam... 725 0.0
gi|148656743|ref|YP_001276948.1| phosphoribosylformylglycin... 715 0.0
gi|113940519|ref|ZP_01426350.1| phosphoribosylformylglycina... 711 0.0
gi|118046346|ref|ZP_01514997.1| phosphoribosylformylglycina... 705 0.0
gi|156741776|ref|YP_001431905.1| phosphoribosylformylglycin... 704 0.0
gi|91200214|emb|CAJ73258.1| similar to Phosphoribosylformyl... 653 0.0
gi|87311379|ref|ZP_01093500.1| phosphoribosylformylglycinam... 645 0.0
gi|57234830|ref|YP_181125.1| phosphoribosylformylglycinamid... 645 0.0
gi|73748224|ref|YP_307463.1| phosphoribosylformylglycinamid... 633 e-179
gi|147669006|ref|YP_001213824.1| phosphoribosylformylglycin... 631 e-179
gi|32473676|ref|NP_866670.1| phosphoribosylformylglycinamid... 614 e-174
gi|149175437|ref|ZP_01854058.1| phosphoribosylformylglycina... 608 e-172
gi|147677764|ref|YP_001211979.1| phosphoribosylformylglycin... 571 e-161
gi|94986959|ref|YP_594892.1| phosphoribosylformylglycinamid... 548 e-154
gi|120601257|ref|YP_965657.1| Phosphoribosylformylglycinami... 545 e-153
gi|46581583|ref|YP_012391.1| phosphoribosylformylglycinamid... 543 e-152
gi|147921719|ref|YP_684461.1| putative phosphoribosylformyl... 541 e-152
gi|78358231|ref|YP_389680.1| Phosphoribosylformylglycinamid... 537 e-150
gi|82548296|gb|ABB82986.1| phosphoribosylformylglycinamidin... 535 e-150
gi|118743819|ref|ZP_01591820.1| phosphoribosylformylglycina... 533 e-149
gi|85858204|ref|YP_460406.1| phosphoribosylformylglycinamid... 532 e-149
gi|78223148|ref|YP_384895.1| Phosphoribosylformylglycinamid... 531 e-148
gi|77918932|ref|YP_356747.1| phosphoribosylformylglycinamid... 523 e-146
gi|145620681|ref|ZP_01776703.1| Phosphoribosylformylglycina... 517 e-144
gi|39996734|ref|NP_952685.1| phosphoribosylformylglycinamid... 516 e-144
gi|110601447|ref|ZP_01389633.1| phosphoribosylformylglycina... 508 e-142
gi|94263059|ref|ZP_01286878.1| Phosphoribosylformylglycinam... 507 e-142
gi|94269831|ref|ZP_01291575.1| Phosphoribosylformylglycinam... 506 e-141
gi|95930094|ref|ZP_01312833.1| Phosphoribosylformylglycinam... 498 e-139
gi|148264123|ref|YP_001230829.1| phosphoribosylformylglycin... 498 e-139
gi|118579579|ref|YP_900829.1| phosphoribosylformylglycinami... 494 e-138
gi|150403102|ref|YP_001330396.1| Phosphoribosylformylglycin... 493 e-137
gi|42524400|ref|NP_969780.1| phosphoribosylformylglycinamid... 492 e-137
gi|134046522|ref|YP_001098007.1| Phosphoribosylformylglycin... 489 e-136
gi|45357742|ref|NP_987299.1| Phosphoribosylformylglycinamid... 487 e-135
gi|150385148|ref|ZP_01923799.1| Phosphoribosylformylglycina... 485 e-135
gi|58584529|ref|YP_198102.1| Phosphoribosylformylglycinamid... 480 e-133
gi|150399926|ref|YP_001323693.1| Phosphoribosylformylglycin... 475 e-132
gi|58696748|ref|ZP_00372289.1| phosphoribosylformylglycinam... 475 e-132
gi|56417048|ref|YP_154122.1| phosphoribosylformylglycinamid... 473 e-131
gi|149199267|ref|ZP_01876305.1| phosphoribosylformylglycina... 471 e-131
gi|68171200|ref|ZP_00544606.1| Phosphoribosylformylglycinam... 471 e-130
gi|58617401|ref|YP_196600.1| Phosphoribosylformylglycinamid... 470 e-130
gi|126179575|ref|YP_001047540.1| Phosphoribosylformylglycin... 469 e-130
gi|73667272|ref|YP_303288.1| Phosphoribosylformylglycinamid... 469 e-130
gi|88602352|ref|YP_502530.1| phosphoribosylformylglycinamid... 469 e-130
gi|57239379|ref|YP_180515.1| putative phosphoribosylformylg... 468 e-130
gi|154150015|ref|YP_001403633.1| Phosphoribosylformylglycin... 466 e-129
gi|42520738|ref|NP_966653.1| phosphoribosylformylglycinamid... 462 e-128
gi|88606986|ref|YP_504834.1| putative phosphoribosylformylg... 449 e-124
gi|149918900|ref|ZP_01907386.1| Phosphoribosylformylglycina... 447 e-123
gi|88607991|ref|YP_506684.1| putative phosphoribosylformylg... 424 e-116
gi|52550037|gb|AAU83886.1| phosphoribosylformylglycinamidin... 409 e-112
gi|11499524|ref|NP_070765.1| phosphoribosylformylglycinamid... 406 e-111
gi|52549856|gb|AAU83705.1| phosphoribosylformylglycinamidin... 404 e-110
gi|48478277|ref|YP_023983.1| phosphoribosylformylglycinamid... 399 e-109
gi|16082093|ref|NP_394526.1| phosphoribosylformylglycinamid... 390 e-106
gi|13541352|ref|NP_111040.1| phosphoribosylformylglycinamid... 388 e-106
gi|116747880|ref|YP_844567.1| Phosphoribosylformylglycinami... 373 e-101
gi|121541624|ref|ZP_01673373.1| Phosphoribosylformylglycina... 373 e-101
gi|126008840|ref|ZP_01709411.1| hypothetical protein Faci_0... 357 1e-96
gi|116873203|ref|YP_849984.1| phosphoribosylformylglycinami... 328 9e-88
gi|46907999|ref|YP_014388.1| phosphoribosylformylglycinamid... 327 2e-87
gi|153198058|ref|ZP_01942208.1| phosphoribosylformylglycina... 327 2e-87
gi|47093695|ref|ZP_00231448.1| phosphoribosylformylglycinam... 327 3e-87
gi|16800947|ref|NP_471215.1| phosphoribosylformylglycinamid... 327 3e-87
gi|153202728|ref|ZP_01944205.1| phosphoribosylformylglycina... 327 3e-87
gi|16803809|ref|NP_465294.1| phosphoribosylformylglycinamid... 326 4e-87
gi|108803837|ref|YP_643774.1| phosphoribosylformylglycinami... 325 7e-87
gi|153174960|ref|ZP_01930395.1| phosphoribosylformylglycina... 325 9e-87
gi|89209625|ref|ZP_01188020.1| Phosphoribosylformylglycinam... 325 1e-86
gi|153007199|ref|YP_001381524.1| phosphoribosylformylglycin... 323 2e-86
gi|116512323|ref|YP_809539.1| Phosphoribosylformylglycinami... 323 2e-86
gi|47095696|ref|ZP_00233303.1| phosphoribosylformylglycinam... 323 2e-86
gi|138893919|ref|YP_001124372.1| Phosphoribosylformylglycin... 323 2e-86
gi|125623815|ref|YP_001032298.1| phosphoribosylformylglycin... 323 4e-86
gi|20807293|ref|NP_622464.1| Phosphoribosylformylglycinamid... 322 5e-86
gi|56418798|ref|YP_146116.1| phosphoribosylformylglycinamid... 320 2e-85
gi|119509347|ref|ZP_01628496.1| Phosphoribosylformylglycina... 320 3e-85
gi|86160630|ref|YP_467415.1| phosphoribosylformylglycinamid... 320 3e-85
gi|15673512|ref|NP_267686.1| phosphoribosylformylglycinamid... 319 5e-85
gi|76796709|ref|ZP_00779064.1| Phosphoribosylformylglycinam... 317 2e-84
gi|114844767|ref|ZP_01455205.1| phosphoribosylformylglycina... 317 2e-84
gi|75909841|ref|YP_324137.1| phosphoribosylformylglycinamid... 316 3e-84
gi|94984172|ref|YP_603536.1| phosphoribosylformylglycinamid... 316 4e-84
gi|145622274|ref|ZP_01778235.1| phosphoribosylformylglycina... 315 5e-84
gi|15805258|ref|NP_293946.1| phosphoribosylformylglycinamid... 315 6e-84
gi|52079132|ref|YP_077923.1| phosphoribosylformylglycinamid... 314 2e-83
gi|149182714|ref|ZP_01861180.1| phosphoribosylformylglycina... 314 2e-83
gi|134300205|ref|YP_001113701.1| phosphoribosylformylglycin... 313 2e-83
gi|46201813|ref|ZP_00054280.2| COG0046: Phosphoribosylformy... 313 3e-83
gi|118466281|ref|YP_880019.1| phosphoribosylformylglycinami... 313 3e-83
gi|150388751|ref|YP_001318800.1| phosphoribosylformylglycin... 313 4e-83
gi|41406733|ref|NP_959569.1| phosphoribosylformylglycinamid... 312 6e-83
gi|37521682|ref|NP_925059.1| phosphoribosylformylglycinamid... 311 1e-82
gi|152974114|ref|YP_001373631.1| phosphoribosylformylglycin... 310 2e-82
gi|69246320|ref|ZP_00603893.1| Phosphoribosylformylglycinam... 310 2e-82
gi|89101009|ref|ZP_01173852.1| phosphoribosylformylglycinam... 310 2e-82
gi|116617835|ref|YP_818206.1| Phosphoribosylformylglycinami... 310 3e-82
gi|16077716|ref|NP_388530.1| phosphoribosylformylglycinamid... 310 4e-82
gi|89204805|ref|ZP_01183381.1| Phosphoribosylformylglycinam... 309 4e-82
gi|17231144|ref|NP_487692.1| phosphoribosylformylglycinamid... 309 5e-82
gi|124521776|ref|ZP_01696621.1| phosphoribosylformylglycina... 309 6e-82
gi|47569938|ref|ZP_00240603.1| phosphoribosylformylglycinam... 308 7e-82
gi|28379218|ref|NP_786110.1| phosphoribosylformylglycinamid... 308 9e-82
gi|30018537|ref|NP_830168.1| phosphoribosylformylglycinamid... 308 9e-82
gi|126656683|ref|ZP_01727897.1| phosphoribosylformylglycina... 308 1e-81
gi|83590878|ref|YP_430887.1| phosphoribosylformylglycinamid... 307 2e-81
gi|49479094|ref|YP_034616.1| phosphoribosylformylglycinamid... 307 2e-81
gi|30260467|ref|NP_842844.1| phosphoribosylformylglycinamid... 307 2e-81
gi|75759928|ref|ZP_00739999.1| Phosphoribosylformylglycinam... 306 3e-81
gi|52144952|ref|YP_081878.1| phosphoribosylformylglycinamid... 306 4e-81
gi|144897482|emb|CAM74346.1| Phosphoribosylformylglycinamid... 306 5e-81
gi|42779404|ref|NP_976651.1| phosphoribosylformylglycinamid... 305 6e-81
gi|22299226|ref|NP_682473.1| phosphoribosylformylglycinamid... 305 6e-81
gi|113476205|ref|YP_722266.1| phosphoribosylformylglycinami... 305 7e-81
gi|119493557|ref|ZP_01624222.1| Phosphoribosylformylglycina... 304 2e-80
gi|126649612|ref|ZP_01721853.1| phosphoribosylformylglycina... 303 3e-80
gi|54022540|ref|YP_116782.1| phosphoribosylformylglycinamid... 303 3e-80
gi|15607943|ref|NP_215318.1| phosphoribosylformylglycinamid... 303 4e-80
gi|15840214|ref|NP_335251.1| phosphoribosylformylglycinamid... 301 9e-80
gi|124600175|gb|EAY59185.1| phosphoribosylformylglycinamidi... 301 9e-80
gi|25009003|sp|Q8PYK1|PURL_METMA Phosphoribosylformylglycin... 301 1e-79
gi|81255344|ref|ZP_00879826.1| COG0046: Phosphoribosylformy... 301 1e-79
gi|146297001|ref|YP_001180772.1| phosphoribosylformylglycin... 301 1e-79
gi|120406067|ref|YP_955896.1| phosphoribosylformylglycinami... 301 2e-79
gi|20093935|ref|NP_613782.1| Phosphoribosylformylglycinamid... 301 2e-79
gi|156938039|ref|YP_001435835.1| phosphoribosylformylglycin... 300 2e-79
gi|154685145|ref|YP_001420306.1| PurL [Bacillus amyloliquef... 300 2e-79
gi|21226962|ref|NP_632884.1| Phosphoribosylformylglycinamid... 300 3e-79
gi|15828188|ref|NP_302451.1| phosphoribosylformylglycinamid... 300 3e-79
gi|68229525|ref|ZP_00568719.1| Phosphoribosylformylglycinam... 300 4e-79
gi|29376329|ref|NP_815483.1| phosphoribosylformylglycinamid... 300 4e-79
gi|1144520|gb|AAB41455.1| phosphoribosylformylglycinamidine... 299 5e-79
gi|15669450|ref|NP_248260.1| phosphoribosylformylglycinamid... 299 5e-79
gi|58337819|ref|YP_194404.1| phosphoribosylformylglycinamid... 299 6e-79
gi|23125357|ref|ZP_00107294.1| COG0046: Phosphoribosylformy... 298 7e-79
gi|50843424|ref|YP_056651.1| phosphoribosylformylglycinamid... 298 8e-79
gi|67921896|ref|ZP_00515412.1| Phosphoribosylformylglycinam... 298 1e-78
gi|119718545|ref|YP_925510.1| phosphoribosylformylglycinami... 298 1e-78
gi|111610228|gb|ABH11607.1| phosphoribosylformylglycinamidi... 298 1e-78
gi|37913021|gb|AAR05350.1| predicted phosphoribosylformylgl... 297 2e-78
gi|117929281|ref|YP_873832.1| phosphoribosylformylglycinami... 296 3e-78
gi|91773985|ref|YP_566677.1| phosphoribosylformylglycinamid... 296 4e-78
gi|145222222|ref|YP_001132900.1| phosphoribosylformylglycin... 296 4e-78
gi|21222481|ref|NP_628260.1| phosphoribosylformylglycinamid... 295 8e-78
gi|148256696|ref|YP_001241281.1| Phosphoribosylformylglycin... 295 8e-78
gi|81428273|ref|YP_395273.1| Phospho ribosylformylglycinami... 295 9e-78
gi|78188986|ref|YP_379324.1| Phosphoribosylformylglycinamid... 295 1e-77
gi|20092848|ref|NP_618923.1| phosphoribosylformylglycinamid... 295 1e-77
gi|23098200|ref|NP_691666.1| phosphoribosylformylglycinamid... 295 1e-77
gi|29830681|ref|NP_825315.1| phosphoribosylformylglycinamid... 294 1e-77
gi|110598338|ref|ZP_01386612.1| phosphoribosylformylglycina... 294 2e-77
gi|85373938|ref|YP_458000.1| phosphoribosylformylglycinamid... 294 2e-77
gi|31789372|gb|AAP58489.1| putative phosphoribosylformylgly... 293 2e-77
gi|15679373|ref|NP_276490.1| phosphoribosylformylglycinamid... 293 2e-77
gi|90961643|ref|YP_535559.1| Phosphoribosylformylglycinamid... 293 3e-77
gi|146339784|ref|YP_001204832.1| Phosphoribosylformylglycin... 293 3e-77
gi|83592047|ref|YP_425799.1| Phosphoribosylformylglycinamid... 293 3e-77
gi|28572944|ref|NP_789724.1| phosphoribosylformylglycinamid... 293 4e-77
gi|28493761|ref|NP_787922.1| phosphoribosylformylglycinamid... 293 4e-77
gi|78044209|ref|YP_359920.1| phosphoribosylformylglycinamid... 293 4e-77
gi|68054852|ref|ZP_00539002.1| Phosphoribosylformylglycinam... 292 6e-77
gi|85708525|ref|ZP_01039591.1| phosphoribosylformylglycinam... 292 7e-77
gi|56751503|ref|YP_172204.1| phosphoribosylformylglycinamid... 291 2e-76
gi|15613192|ref|NP_241495.1| phosphoribosylformylglycinamid... 290 2e-76
gi|72160562|ref|YP_288219.1| phosphoribosylformylglycinamid... 290 2e-76
gi|62423725|ref|ZP_00378883.1| COG0046: Phosphoribosylformy... 290 2e-76
gi|21674063|ref|NP_662128.1| phosphoribosylformylglycinamid... 290 3e-76
gi|56962804|ref|YP_174530.1| phosphoribosylformylglycinamid... 290 3e-76
gi|111226063|ref|YP_716857.1| Phosphoribosylformylglycinami... 290 4e-76
gi|88854915|ref|ZP_01129581.1| phosphoribosylformylglycinam... 289 5e-76
gi|14916653|sp|P72644|PURL_SYNY3 Phosphoribosylformylglycin... 289 6e-76
gi|16329238|ref|NP_439966.1| phosphoribosylformylglycinamid... 289 6e-76
gi|49475724|ref|YP_033765.1| phosphoribosylformylglycinamid... 288 8e-76
gi|46199457|ref|YP_005124.1| phosphoribosylformylglycinamid... 288 8e-76
gi|15606878|ref|NP_214258.1| phosphoribosylformylglycinamid... 288 1e-75
gi|110633630|ref|YP_673838.1| phosphoribosylformylglycinami... 288 1e-75
gi|114328334|ref|YP_745491.1| phosphoribosylformylglycinami... 288 1e-75
gi|126437494|ref|YP_001073185.1| phosphoribosylformylglycin... 287 2e-75
gi|116669106|ref|YP_830039.1| phosphoribosylformylglycinami... 287 2e-75
gi|86610231|ref|YP_478993.1| phosphoribosylformylglycinamid... 286 3e-75
gi|118587336|ref|ZP_01544762.1| phosphoribosylformylglycina... 286 3e-75
gi|116491150|ref|YP_810694.1| Phosphoribosylformylglycinami... 286 4e-75
gi|108801509|ref|YP_641706.1| phosphoribosylformylglycinami... 286 4e-75
gi|84490248|ref|YP_448480.1| PurL [Methanosphaera stadtmana... 285 6e-75
gi|68548999|ref|ZP_00588467.1| Phosphoribosylformylglycinam... 285 7e-75
gi|148556871|ref|YP_001264453.1| phosphoribosylformylglycin... 285 8e-75
gi|50955787|ref|YP_063075.1| phosphoribosylformylglycinamid... 285 1e-74
gi|116495231|ref|YP_806965.1| Phosphoribosylformylglycinami... 284 1e-74
gi|114704295|ref|ZP_01437203.1| phosphoribosylformylglycina... 284 2e-74
gi|134103564|ref|YP_001109225.1| phosphoribosylformylglycin... 284 2e-74
gi|150401881|ref|YP_001325647.1| phosphoribosylformylglycin... 284 2e-74
gi|57640132|ref|YP_182610.1| phosphoribosylformylglycinamid... 284 2e-74
gi|51893993|ref|YP_076684.1| phosphoribosylformylglycinamid... 283 3e-74
gi|73668082|ref|YP_304097.1| phosphoribosylformylglycinamid... 283 3e-74
gi|91976230|ref|YP_568889.1| phosphoribosylformylglycinamid... 283 3e-74
gi|118616264|ref|YP_904596.1| phosphoribosylformylglycinami... 283 4e-74
gi|87200270|ref|YP_497527.1| phosphoribosylformylglycinamid... 283 4e-74
gi|31789477|gb|AAP58590.1| putative phosphoribosylformylgly... 283 5e-74
gi|86743092|ref|YP_483492.1| phosphoribosylformylglycinamid... 283 5e-74
gi|121601697|ref|YP_989150.1| phosphoribosylformylglycinami... 282 6e-74
gi|148271907|ref|YP_001221468.1| phosphoribosylformylglycin... 282 7e-74
gi|149882852|ref|YP_001294830.1| putative phosphoribosyl fo... 282 7e-74
gi|116493200|ref|YP_804935.1| Phosphoribosylformylglycinami... 281 1e-73
gi|119713259|gb|ABL97325.1| phosphoribosylformylglycinamidi... 281 1e-73
gi|104774302|ref|YP_619282.1| Phosphoribosylformylglycinami... 281 2e-73
gi|18976571|ref|NP_577928.1| phosphoribosylformylglycinamid... 280 2e-73
gi|119357078|ref|YP_911722.1| phosphoribosylformylglycinami... 280 2e-73
gi|67917641|ref|ZP_00511246.1| Phosphoribosylformylglycinam... 280 2e-73
gi|145219660|ref|YP_001130369.1| phosphoribosylformylglycin... 280 2e-73
gi|67939860|ref|ZP_00532344.1| Phosphoribosylformylglycinam... 280 3e-73
gi|149184814|ref|ZP_01863132.1| phosphoribosylformylglycina... 279 4e-73
gi|119964003|ref|YP_946435.1| phosphoribosylformylglycinami... 279 5e-73
gi|124005761|ref|ZP_01690600.1| phosphoribosylformylglycina... 279 5e-73
gi|152968011|ref|YP_001363795.1| phosphoribosylformylglycin... 278 1e-72
gi|118588569|ref|ZP_01545977.1| phosphoribosylformylglycina... 277 2e-72
gi|33239455|ref|NP_874397.1| phosphoribosylformylglycinamid... 277 2e-72
gi|71083828|ref|YP_266548.1| Phosphoribosylformylglycinamid... 277 2e-72
gi|67460924|sp|Q7VEK9|PURL_PROMA Phosphoribosylformylglycin... 276 3e-72
gi|86750823|ref|YP_487319.1| phosphoribosylformylglycinamid... 276 3e-72
gi|116074278|ref|ZP_01471540.1| phosphoribosylformylglycina... 276 4e-72
gi|148261648|ref|YP_001235775.1| phosphoribosylformylglycin... 276 5e-72
gi|148643402|ref|YP_001273915.1| phosphoribosylformylglycin... 276 5e-72
gi|14591693|ref|NP_143781.1| phosphoribosylformylglycinamid... 276 5e-72
gi|32267324|ref|NP_861356.1| phosphoribosylformylglycinamid... 276 5e-72
gi|68553000|ref|ZP_00592383.1| Phosphoribosylformylglycinam... 275 9e-72
gi|92090040|ref|ZP_01274950.1| Phosphoribosylformylglycinam... 275 9e-72
gi|154248011|ref|YP_001418969.1| phosphoribosylformylglycin... 275 1e-71
gi|152990642|ref|YP_001356364.1| phosphoribosylformylglycin... 275 1e-71
gi|85715184|ref|ZP_01046168.1| phosphoribosylformylglycinam... 274 2e-71
gi|114797329|ref|YP_760643.1| phosphoribosylformylglycinami... 274 2e-71
gi|148238339|ref|YP_001223726.1| Phosphoribosylformylglycin... 274 2e-71
gi|78776746|ref|YP_393061.1| Phosphoribosylformylglycinamid... 273 2e-71
gi|87123346|ref|ZP_01079197.1| Phosphoribosylformylglycinam... 273 3e-71
gi|103487678|ref|YP_617239.1| phosphoribosylformylglycinami... 273 3e-71
gi|90423102|ref|YP_531472.1| phosphoribosylformylglycinamid... 273 3e-71
gi|92117186|ref|YP_576915.1| phosphoribosylformylglycinamid... 273 4e-71
gi|86606032|ref|YP_474795.1| phosphoribosylformylglycinamid... 273 4e-71
gi|15894932|ref|NP_348281.1| bifunctional enzyme phosphorib... 273 4e-71
gi|27380830|ref|NP_772359.1| phosphoribosylformylglycinamid... 272 7e-71
gi|149194633|ref|ZP_01871729.1| phosphoribosylformylglycina... 272 8e-71
gi|56551716|ref|YP_162555.1| phosphoribosylformylglycinamid... 271 9e-71
gi|154253027|ref|YP_001413851.1| phosphoribosylformylglycin... 271 9e-71
gi|78183587|ref|YP_376021.1| phosphoribosylformylglycinamid... 271 1e-70
gi|148543379|ref|YP_001270749.1| phosphoribosylformylglycin... 271 1e-70
gi|15811163|gb|AAL08837.1|AF308671_1 hypothetical phosphori... 271 1e-70
gi|39934667|ref|NP_946943.1| phosphoribosylformylglycinamid... 271 2e-70
gi|111021806|ref|YP_704778.1| phosphoribosylformylglycinami... 270 2e-70
gi|33864542|ref|NP_896101.1| phosphoribosylformylglycinamid... 270 3e-70
gi|75675500|ref|YP_317921.1| phosphoribosylformylglycinamid... 269 4e-70
gi|110799768|ref|YP_695124.1| phosphoribosylformylglycinami... 269 7e-70
gi|1346917|sp|P35852|PURL_LACCA Phosphoribosylformylglycina... 268 9e-70
gi|34557223|ref|NP_907038.1| phosphoribosylformylglycinamid... 268 1e-69
gi|116071806|ref|ZP_01469074.1| phosphoribosylformylglycina... 267 2e-69
gi|83858770|ref|ZP_00952292.1| phosphoribosylformylglycinam... 267 2e-69
gi|84684741|ref|ZP_01012641.1| phosphoribosylformylglycinam... 267 3e-69
gi|84518953|ref|ZP_01006302.1| phosphoribosylformylglycinam... 266 3e-69
gi|94497290|ref|ZP_01303861.1| phosphoribosylformylglycinam... 266 3e-69
gi|90420938|ref|ZP_01228843.1| phosphoribosylformylglycinam... 266 4e-69
gi|6685118|gb|AAF23789.1|AF213822_4 PUR-Q [Zymomonas mobilis] 266 4e-69
gi|88809361|ref|ZP_01124869.1| phosphoribosylformylglycinam... 266 5e-69
gi|115523631|ref|YP_780542.1| phosphoribosylformylglycinami... 266 5e-69
gi|18309662|ref|NP_561596.1| phosphoribosylformylglycinamid... 265 7e-69
gi|153009717|ref|YP_001370932.1| phosphoribosylformylglycin... 265 8e-69
gi|113932507|ref|ZP_01418409.1| phosphoribosylformylglycina... 265 9e-69
gi|148241102|ref|YP_001226259.1| Phosphoribosylformylglycin... 265 9e-69
gi|119871620|ref|YP_929627.1| phosphoribosylformylglycinami... 265 9e-69
gi|113955261|ref|YP_729242.1| phosphoribosylformylglycinami... 265 1e-68
gi|110801898|ref|YP_697996.1| phosphoribosylformylglycinami... 265 1e-68
gi|23501724|ref|NP_697851.1| phosphoribosylformylglycinamid... 265 1e-68
gi|126354385|ref|ZP_01711396.1| phosphoribosylformylglycina... 265 1e-68
gi|14916674|sp|Q9RHW9|PURL_CORAM Phosphoribosylformylglycin... 264 2e-68
gi|78186951|ref|YP_374994.1| Phosphoribosylformylglycinamid... 264 2e-68
gi|116625014|ref|YP_827170.1| phosphoribosylformylglycinami... 264 2e-68
gi|118473588|ref|YP_890052.1| phosphoribosylformylglycinami... 264 2e-68
gi|153897965|ref|ZP_02018532.1| phosphoribosylformylglycina... 264 2e-68
gi|156452591|ref|ZP_02058961.1| phosphoribosylformylglycina... 264 2e-68
gi|154243050|ref|ZP_02024611.1| phosphoribosylformylglycina... 263 2e-68
gi|49474337|ref|YP_032379.1| phosphoribosylformylglycinamid... 263 3e-68
gi|14916670|sp|Q9KH12|PURL_RHIFR Phosphoribosylformylglycin... 263 3e-68
gi|15897545|ref|NP_342150.1| Phosphoribosylformylglycinamid... 263 4e-68
gi|86150796|ref|ZP_01069012.1| phosphoribosylformylglycinam... 262 6e-68
gi|62289784|ref|YP_221577.1| phosphoribosylformylglycinamid... 262 6e-68
gi|119884235|ref|ZP_01650480.1| phosphoribosylformylglycina... 262 7e-68
gi|156719320|ref|ZP_02060960.1| phosphoribosylformylglycina... 261 1e-67
gi|54297599|ref|YP_123968.1| Phosphoribosylformylglycinamid... 261 1e-67
gi|54294567|ref|YP_126982.1| Phosphoribosylformylglycinamid... 261 1e-67
gi|17987410|ref|NP_540044.1| phosphoribosylformylglycinamid... 261 1e-67
gi|33862276|ref|NP_893836.1| phosphoribosylformylglycinamid... 261 1e-67
gi|124021717|ref|YP_001016024.1| phosphoribosylformylglycin... 261 1e-67
gi|124024715|ref|YP_001013831.1| phosphoribosylformylglycin... 261 2e-67
gi|58040729|ref|YP_192693.1| phosphoribosylformylglycinamid... 260 2e-67
gi|14521941|ref|NP_127418.1| phosphoribosylformylglycinamid... 260 2e-67
gi|123965237|ref|YP_001010318.1| phosphoribosylformylglycin... 260 2e-67
gi|78211561|ref|YP_380340.1| phosphoribosylformylglycinamid... 260 2e-67
gi|118737787|ref|ZP_01586190.1| phosphoribosylformylglycina... 260 2e-67
gi|86150665|ref|ZP_01068886.1| phosphoribosylformylglycinam... 260 2e-67
gi|145296583|ref|YP_001139404.1| hypothetical protein cgR_2... 260 3e-67
gi|153951583|ref|YP_001397953.1| phosphoribosylformylglycin... 259 3e-67
gi|86152446|ref|ZP_01070651.1| phosphoribosylformylglycinam... 259 4e-67
gi|78778388|ref|YP_396500.1| phosphoribosylformylglycinamid... 259 4e-67
gi|57237783|ref|YP_179031.1| phosphoribosylformylglycinamid... 259 4e-67
gi|125973073|ref|YP_001036983.1| phosphoribosylformylglycin... 259 4e-67
gi|126695340|ref|YP_001090226.1| phosphoribosylformylglycin... 259 5e-67
gi|52841906|ref|YP_095705.1| phosphoribosylformylglycinamid... 259 5e-67
gi|123967539|ref|YP_001008397.1| phosphoribosylformylglycin... 259 5e-67
gi|83814563|ref|YP_446754.1| phosphoribosylformylglycinamid... 259 5e-67
gi|57157719|dbj|BAD83826.1| phosphoribosyl-formylglycinamid... 258 8e-67
gi|16126739|ref|NP_421303.1| phosphoribosylformylglycinamid... 258 9e-67
gi|152993151|ref|YP_001358872.1| phosphoribosylformylglycin... 258 1e-66
gi|145592718|ref|YP_001157015.1| phosphoribosylformylglycin... 258 1e-66
gi|114569578|ref|YP_756258.1| phosphoribosylformylglycinami... 258 1e-66
gi|118444451|ref|YP_878491.1| phosphoribosylformylglycinami... 257 2e-66
gi|15792284|ref|NP_282107.1| phosphoribosylformylglycinamid... 257 3e-66
gi|19553784|ref|NP_601786.1| phosphoribosylformylglycinamid... 256 3e-66
gi|146304728|ref|YP_001192044.1| phosphoribosylformylglycin... 256 3e-66
gi|126462364|ref|YP_001043478.1| phosphoribosylformylglycin... 256 3e-66
gi|116327603|ref|YP_797323.1| Phosphoribosylformylglycinami... 256 4e-66
gi|154507982|ref|ZP_02043624.1| hypothetical protein ACTODO... 256 4e-66
gi|72383167|ref|YP_292522.1| phosphoribosylformylglycinamid... 256 5e-66
gi|110831823|sp|Q3J273|PURL_RHOS4 Phosphoribosylformylglyci... 255 9e-66
gi|15889151|ref|NP_354832.1| phosphoribosylformylglycinamid... 255 9e-66
gi|116753423|ref|YP_842541.1| phosphoribosylformylglycinami... 255 1e-65
gi|116252358|ref|YP_768196.1| putative phosphoribosylformyl... 255 1e-65
gi|77463508|ref|YP_353012.1| phosphoribosylformylglycinamid... 255 1e-65
gi|13470370|ref|NP_101938.1| phosphoribosylformylglycinamid... 254 1e-65
gi|145592374|ref|YP_001154376.1| phosphoribosylformylglycin... 254 1e-65
gi|25029036|ref|NP_739090.1| phosphoribosylformylglycinamid... 253 3e-65
gi|15965532|ref|NP_385885.1| phosphoribosylformylglycinamid... 253 5e-65
gi|57242377|ref|ZP_00370316.1| phosphoribosylformylglycinam... 252 7e-65
gi|87301554|ref|ZP_01084394.1| phosphoribosylformylglycinam... 252 8e-65
gi|94971648|ref|YP_593696.1| phosphoribosylformylglycinamid... 251 1e-64
gi|86357901|ref|YP_469793.1| phosphoribosylformylglycinamid... 251 1e-64
gi|33860563|ref|NP_892124.1| phosphoribosylformylglycinamid... 251 2e-64
gi|24214023|ref|NP_711504.1| Phosphoribosylformylglycinamid... 251 2e-64
gi|126728665|ref|ZP_01744480.1| phosphoribosylformylglycina... 250 2e-64
gi|27467685|ref|NP_764322.1| phosphoribosylformylglycinamid... 250 2e-64
gi|57866554|ref|YP_188239.1| phosphoribosylformylglycinamid... 250 2e-64
gi|148323389|gb|EDK88639.1| phosphoribosylformylglycinamidi... 250 3e-64
gi|45658248|ref|YP_002334.1| phosphoribosylformylglycinamid... 250 3e-64
gi|153940576|ref|YP_001391877.1| phosphoribosylformylglycin... 250 3e-64
gi|150396717|ref|YP_001327184.1| phosphoribosylformylglycin... 249 4e-64
gi|153933343|ref|YP_001384822.1| phosphoribosylformylglycin... 249 5e-64
gi|70726889|ref|YP_253803.1| phosphoribosylformylglycinamid... 248 9e-64
gi|148380535|ref|YP_001255076.1| formylglycinamidine ribonu... 248 9e-64
gi|150015939|ref|YP_001308193.1| phosphoribosylformylglycin... 248 1e-63
gi|15921789|ref|NP_377458.1| hypothetical phosphoribosylfor... 248 1e-63
gi|56696746|ref|YP_167107.1| phosphoribosylformylglycinamid... 248 1e-63
gi|114768950|ref|ZP_01446576.1| phosphoribosylformylglycina... 247 2e-63
gi|73663030|ref|YP_301811.1| phosphoribosylformylglycinamid... 247 2e-63
gi|114766193|ref|ZP_01445193.1| phosphoribosylformylglycina... 247 2e-63
gi|15924059|ref|NP_371593.1| phosphoribosylformylglycinamid... 247 3e-63
gi|21282681|ref|NP_645769.1| phosphoribosylformylglycinamid... 246 3e-63
gi|27262434|gb|AAN87498.1| Phosphoribosylformylglycinamidin... 246 3e-63
gi|156868005|gb|EDO61377.1| hypothetical protein CLOLEP_017... 246 4e-63
gi|146276943|ref|YP_001167102.1| phosphoribosylformylglycin... 246 4e-63
gi|154174427|ref|YP_001408431.1| phosphoribosylformylglycin... 244 1e-62
gi|69933363|ref|ZP_00628565.1| Phosphoribosylformylglycinam... 244 1e-62
gi|82750680|ref|YP_416421.1| phosphoribosylformylglycinamid... 244 2e-62
gi|86138824|ref|ZP_01057396.1| phosphoribosylformylglycinam... 243 3e-62
gi|57167880|ref|ZP_00367020.1| phosphoribosylformylglycinam... 243 3e-62
gi|118195602|gb|ABK78520.1| phosphoribosylformylglycinamidi... 243 3e-62
gi|126460489|ref|YP_001056767.1| phosphoribosylformylglycin... 243 4e-62
gi|110680413|ref|YP_683420.1| phosphoribosylformylglycinami... 243 4e-62
gi|18311793|ref|NP_558460.1| phosphoribosylformylglycinamid... 243 5e-62
gi|57241019|ref|ZP_00368966.1| phosphoribosylformylglycinam... 243 5e-62
gi|118475518|ref|YP_891746.1| phosphoribosylformylglycinami... 242 7e-62
gi|153812459|ref|ZP_01965127.1| hypothetical protein RUMOBE... 242 9e-62
gi|126737906|ref|ZP_01753636.1| phosphoribosylformylglycina... 241 1e-61
gi|121535472|ref|ZP_01667282.1| phosphoribosylformylglycina... 241 1e-61
gi|68535420|ref|YP_250125.1| phosphoribosylformylglycinamid... 239 4e-61
gi|109891946|sp|Q4JXF0|PURL_CORJK Phosphoribosylformylglyci... 239 5e-61
gi|46203113|ref|ZP_00052056.2| COG0046: Phosphoribosylformy... 239 5e-61
gi|28210734|ref|NP_781678.1| phosphoribosylformylglycinamid... 239 7e-61
gi|84503071|ref|ZP_01001167.1| phosphoribosylformylglycinam... 238 8e-61
gi|49483233|ref|YP_040457.1| putative phosphoribosylformylg... 238 1e-60
gi|19704325|ref|NP_603887.1| Phosphoribosylformylglycinamid... 238 1e-60
gi|148270649|ref|YP_001245109.1| phosphoribosylformylglycin... 238 2e-60
gi|12964608|dbj|BAB32670.1| formylglycinamidine ribonucleot... 237 2e-60
gi|15644002|ref|NP_229051.1| phosphoribosylformylglycinamid... 237 2e-60
gi|110667650|ref|YP_657461.1| phosphoribosylformylglycinami... 237 2e-60
gi|106894214|ref|ZP_01361335.1| Phosphoribosylformylglycina... 236 3e-60
gi|126697796|ref|YP_001086693.1| formylglycinamidine ribonu... 236 6e-60
gi|70607345|ref|YP_256215.1| phosphoribosylformylglycinamid... 236 6e-60
gi|153953911|ref|YP_001394676.1| PurL [Clostridium kluyveri... 236 6e-60
gi|89054664|ref|YP_510115.1| phosphoribosylformylglycinamid... 235 1e-59
gi|89071186|ref|ZP_01158377.1| phosphoribosylformylglycinam... 234 1e-59
gi|109647282|ref|ZP_01371186.1| phosphoribosylformylglycina... 234 2e-59
gi|126030641|pdb|2HRU|A unnamed protein product [Thermotoga... 234 3e-59
gi|145956147|ref|ZP_01805144.1| hypothetical protein CdifQ_... 233 4e-59
gi|156863128|gb|EDO56559.1| hypothetical protein CLOL250_02... 233 5e-59
gi|84515575|ref|ZP_01002937.1| phosphoribosylformylglycinam... 232 9e-59
gi|153855871|ref|ZP_01996846.1| hypothetical protein DORLON... 231 1e-58
gi|124485127|ref|YP_001029743.1| carbamoyl-phosphate syntha... 231 1e-58
gi|109671254|ref|ZP_01373515.1| phosphoribosylformylglycina... 231 1e-58
gi|89896680|ref|YP_520167.1| hypothetical protein DSY3934 [... 231 2e-58
gi|15790005|ref|NP_279829.1| PurL [Halobacterium sp. NRC-1]... 231 2e-58
gi|149914755|ref|ZP_01903285.1| phosphoribosylformylglycina... 230 3e-58
gi|153814435|ref|ZP_01967103.1| hypothetical protein RUMTOR... 230 4e-58
gi|124514404|gb|EAY55917.1| Phosphoribosylformylglycinamidi... 229 4e-58
gi|83942616|ref|ZP_00955077.1| phosphoribosylformylglycinam... 229 5e-58
gi|83953857|ref|ZP_00962578.1| phosphoribosylformylglycinam... 229 6e-58
gi|154249777|ref|YP_001410602.1| phosphoribosylformylglycin... 229 6e-58
gi|49259562|pdb|1VK3|A Chain A, Crystal Structure Of Phosph... 228 1e-57
gi|125716914|ref|YP_001034047.1| Phosphoribosylformylglycin... 228 1e-57
gi|154493944|ref|ZP_02033264.1| hypothetical protein PARMER... 228 1e-57
gi|34540136|ref|NP_904615.1| phosphoribosylformylglycinamid... 227 3e-57
gi|149001874|ref|ZP_01826847.1| amidophosphoribosyltransfer... 225 1e-56
gi|157076429|gb|ABV11112.1| phosphoribosylformylglycinamidi... 224 2e-56
gi|148985387|ref|ZP_01818592.1| phosphoribosylaminoimidazol... 223 4e-56
gi|99034828|ref|ZP_01314743.1| hypothetical protein Wendoof... 222 6e-56
gi|126726353|ref|ZP_01742194.1| phosphoribosylformylglycina... 222 1e-55
gi|149006791|ref|ZP_01830477.1| amidophosphoribosyltransfer... 221 1e-55
gi|148996450|ref|ZP_01824168.1| phosphoribosylaminoimidazol... 221 2e-55
gi|149280518|ref|ZP_01886636.1| phosphoribosylformylglycina... 220 3e-55
gi|126735635|ref|ZP_01751380.1| phosphoribosylformylglycina... 220 3e-55
gi|50913418|ref|YP_059390.1| Phosphoribosylformylglycinamid... 220 3e-55
gi|148987774|ref|ZP_01819237.1| phosphoribosylaminoimidazol... 220 3e-55
gi|55378175|ref|YP_136025.1| phosphoribosylformylglycinamid... 220 4e-55
gi|154502541|ref|ZP_02039601.1| hypothetical protein RUMGNA... 219 4e-55
gi|149010910|ref|ZP_01832215.1| phosphoribosylaminoimidazol... 219 4e-55
gi|19745220|ref|NP_606356.1| putative phosphoribosylformylg... 219 7e-55
gi|139437978|ref|ZP_01771531.1| Hypothetical protein COLAER... 219 7e-55
gi|15899990|ref|NP_344594.1| phosphoribosylformylglycinamid... 219 7e-55
gi|154486996|ref|ZP_02028403.1| hypothetical protein BIFADO... 219 7e-55
gi|76798756|ref|ZP_00780973.1| phosphoribosylformylglycinam... 219 8e-55
gi|77414395|ref|ZP_00790549.1| phosphoribosylformylglycinam... 219 8e-55
gi|154483482|ref|ZP_02025930.1| hypothetical protein EUBVEN... 219 8e-55
gi|22536210|ref|NP_687061.1| phosphoribosylformylglycinamid... 218 9e-55
gi|116516503|ref|YP_815489.1| phosphoribosylformylglycinami... 218 1e-54
gi|15902090|ref|NP_357640.1| Phosphoribosylformylglycinamid... 218 1e-54
gi|119025541|ref|YP_909386.1| phosphoribosylformylglycinami... 218 1e-54
gi|139472908|ref|YP_001127623.1| putative phosphoribosylfor... 217 2e-54
gi|116626999|ref|YP_819618.1| Phosphoribosylformylglycinami... 217 2e-54
gi|55822023|ref|YP_140464.1| phosphoribosylformylglycinamid... 217 2e-54
gi|76787165|ref|YP_328751.1| phosphoribosylformylglycinamid... 217 2e-54
gi|150021120|ref|YP_001306474.1| phosphoribosylformylglycin... 216 3e-54
gi|55820134|ref|YP_138576.1| phosphoribosylformylglycinamid... 216 3e-54
gi|81096493|ref|ZP_00874835.1| Phosphoribosylformylglycinam... 216 4e-54
gi|94993419|ref|YP_601517.1| Phosphoribosylformylglycinamid... 216 6e-54
gi|24378558|ref|NP_720513.1| putative phosphoribosylformylg... 215 7e-54
gi|77408734|ref|ZP_00785465.1| phosphoribosylformylglycinam... 215 8e-54
gi|60682623|ref|YP_212767.1| phosphoribosylformylglycinamid... 215 1e-53
gi|56808889|ref|ZP_00366599.1| COG0046: Phosphoribosylformy... 215 1e-53
gi|53714601|ref|YP_100593.1| phosphoribosylformylglycinamid... 215 1e-53
gi|77411213|ref|ZP_00787564.1| phosphoribosylformylglycinam... 214 1e-53
gi|94989532|ref|YP_597632.1| Phosphoribosylformylglycinamid... 214 1e-53
gi|150009124|ref|YP_001303867.1| putative phosphoribosylfor... 214 2e-53
gi|85705366|ref|ZP_01036465.1| phosphoribosylformylglycinam... 214 2e-53
gi|25010099|ref|NP_734494.1| hypothetical protein gbs0024 [... 214 2e-53
gi|146317687|ref|YP_001197399.1| Phosphoribosylformylglycin... 213 3e-53
gi|154149152|ref|YP_001406248.1| phosphoribosylformylglycin... 213 3e-53
gi|156861664|gb|EDO55095.1| hypothetical protein BACUNI_011... 213 3e-53
gi|99080959|ref|YP_613113.1| phosphoribosylformylglycinamid... 213 4e-53
gi|29347143|ref|NP_810646.1| phosphoribosylformylglycinamid... 213 4e-53
gi|38234679|ref|NP_940446.1| Putative phosphoribosylformylg... 213 5e-53
gi|154496429|ref|ZP_02035125.1| hypothetical protein BACCAP... 213 6e-53
gi|146302451|ref|YP_001197042.1| Phosphoribosylformylglycin... 212 8e-53
gi|156108336|gb|EDO10081.1| hypothetical protein BACOVA_044... 212 1e-52
gi|83952315|ref|ZP_00961047.1| phosphoribosylformylglycinam... 211 1e-52
gi|21909556|ref|NP_663824.1| putative phosphoribosylformylg... 211 2e-52
gi|28894933|ref|NP_801283.1| putative phosphoribosylformylg... 211 2e-52
gi|23465676|ref|NP_696279.1| PurL [Bifidobacterium longum N... 211 2e-52
gi|153896345|ref|ZP_02016923.1| phosphoribosylformylglycina... 211 2e-52
gi|46190808|ref|ZP_00120947.2| COG0046: Phosphoribosylformy... 211 2e-52
gi|76802132|ref|YP_327140.1| phosphoribosylformylglycinamid... 210 2e-52
gi|15674269|ref|NP_268442.1| putative phosphoribosylformylg... 210 3e-52
gi|106886950|ref|ZP_01354275.1| phosphoribosylformylglycina... 210 3e-52
gi|71902689|ref|YP_279492.1| phosphoribosylformylglycinamid... 210 3e-52
gi|94987654|ref|YP_595755.1| phosphoribosylformylglycinamid... 210 3e-52
gi|150002686|ref|YP_001297430.1| putative phosphoribosylfor... 209 4e-52
gi|86142816|ref|ZP_01061255.1| putative phosphoribosylformy... 209 7e-52
gi|34763397|ref|ZP_00144348.1| Phosphoribosylformylglycinam... 208 9e-52
gi|88806483|ref|ZP_01122000.1| phosphoribosylformylglycinam... 208 1e-51
gi|153808460|ref|ZP_01961128.1| hypothetical protein BACCAC... 208 1e-51
gi|91214593|ref|ZP_01251566.1| phosphoribosylformylglycinam... 206 4e-51
gi|126663957|ref|ZP_01734951.1| phosphoribosylformylglycine... 206 5e-51
gi|120435405|ref|YP_861091.1| phosphoribosylformylglycinami... 204 2e-50
gi|150024788|ref|YP_001295614.1| Phosphoribosylformylglycin... 204 2e-50
gi|149204007|ref|ZP_01880975.1| phosphoribosylformylglycina... 202 1e-49
gi|83856660|ref|ZP_00950189.1| phosphoribosylformylglycinam... 201 2e-49
gi|86133714|ref|ZP_01052296.1| phosphoribosylformylglycinam... 199 4e-49
gi|88711993|ref|ZP_01106080.1| phosphoribosylformylglycinam... 199 5e-49
gi|120611759|ref|YP_971437.1| phosphoribosylformylglycinami... 199 6e-49
gi|148993884|ref|ZP_01823267.1| phosphoribosylaminoimidazol... 199 7e-49
gi|90021125|ref|YP_526952.1| Phosphoribosylformylglycinamid... 197 3e-48
gi|154707078|ref|YP_001424049.1| phosphoribosylformylglycin... 194 2e-47
gi|29653969|ref|NP_819661.1| phosphoribosylformylglycinamid... 194 2e-47
gi|95927964|ref|ZP_01310716.1| hypothetical protein CburR_0... 194 2e-47
gi|153209736|ref|ZP_01947488.1| phosphoribosylformylglycina... 194 2e-47
gi|110638068|ref|YP_678277.1| phosphoribosylformylglycineam... 194 3e-47
gi|56478946|ref|YP_160535.1| phosphoribosylformylglycinamid... 194 3e-47
gi|56459700|ref|YP_154981.1| phosphoribosylformylglycinamid... 194 3e-47
gi|126642620|ref|YP_001085604.1| phosphoribosylformylglycin... 194 3e-47
gi|90416324|ref|ZP_01224256.1| phosphoribosylformylglycinam... 192 6e-47
gi|89891173|ref|ZP_01202680.1| phosphoribosylformylglycinam... 192 9e-47
gi|126648787|ref|ZP_01721270.1| phosphoribosylformylglycina... 191 1e-46
gi|50085683|ref|YP_047193.1| phosphoribosylformylglycinamid... 191 2e-46
>gi|42526788|ref|NP_971886.1| phosphoribosylformylglycinamidine synthase II [Treponema denticola
ATCC 35405]
gi|41817103|gb|AAS11797.1| phosphoribosylformylglycinamidine synthase II [Treponema denticola
ATCC 35405]
Length = 766
Score = 1541 bits (3991), Expect = 0.0, Method: Composition-based stats.
Identities = 766/766 (100%), Positives = 766/766 (100%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK
Sbjct: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
Query: 61 IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEV 120
IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEV
Sbjct: 61 IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEV 120
Query: 121 SFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGT 180
SFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGT
Sbjct: 121 SFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGT 180
Query: 181 LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPS 240
LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPS
Sbjct: 181 LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPS 240
Query: 241 AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQ 300
AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQ
Sbjct: 241 AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQ 300
Query: 301 GLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVP 360
GLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVP
Sbjct: 301 GLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVP 360
Query: 361 NDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAP 420
NDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAP
Sbjct: 361 NDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAP 420
Query: 421 PKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGN 480
PKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGN
Sbjct: 421 PKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGN 480
Query: 481 VPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTA 540
VPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTA
Sbjct: 481 VPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTA 540
Query: 541 ILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPP 600
ILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPP
Sbjct: 541 ILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPP 600
Query: 601 SLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF 660
SLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF
Sbjct: 601 SLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF 660
Query: 661 KKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKI 720
KKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKI
Sbjct: 661 KKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKI 720
Query: 721 ASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
ASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL
Sbjct: 721 ASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
>gi|76258610|ref|ZP_00766264.1| Phosphoribosylformylglycinamidine synthase II [Chloroflexus
aurantiacus J-10-fl]
gi|76166339|gb|EAO60465.1| Phosphoribosylformylglycinamidine synthase II [Chloroflexus
aurantiacus J-10-fl]
Length = 974
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 390/780 (50%), Positives = 505/780 (64%), Gaps = 24/780 (3%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
+D EL+A+S ALD+ EMRAI+ ++ + R TD E ETIAQTWSEHC HKTFKA++
Sbjct: 171 DDAELMAISQRGVLALDLAEMRAIQAYFVAQGRDPTDGELETIAQTWSEHCSHKTFKARV 230
Query: 62 ---------DIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI----DAPWVLSSFVDN 108
+D + A ++S+I+T++ +AT ++ WVLS+FVDN
Sbjct: 231 QYSQPPEDLSVDSEHYPMLARLAVGNCTIDSLIRTFLMRATQEVLSGRQDEWVLSAFVDN 290
Query: 109 AGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGH 168
AGI+ F +++EVS+K ETHNHPSA+EPFGGANTGVGGVIRDV+GVSARP A DVLCFG
Sbjct: 291 AGILAFGDRHEVSYKVETHNHPSALEPFGGANTGVGGVIRDVLGVSARPIANIDVLCFGM 350
Query: 169 PDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAG 228
PD P P G LHP+RI SGV+ G++DYGNK+GIPTV G V + Y +NPLVYCG G
Sbjct: 351 PDAPPP--PAGVLHPRRIASGVVAGIRDYGNKLGIPTVGGAVLFDPGYTANPLVYCGTVG 408
Query: 229 IAPRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQK 288
+APRG H GD I+ +GG+TGRDG+ GATFSS+ + +T GS+VQIG+PI +K
Sbjct: 409 LAPRGLHPRNVRPGDIIVVMGGRTGRDGIHGATFSSIELTHTTASEVGSAVQIGDPITEK 468
Query: 289 KVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWL 348
K+ +VL+ ARD GLYSAITDCGAGG SSAVGEM + LG +V L +P KY GL PWE+WL
Sbjct: 469 KMLDVLLQARDAGLYSAITDCGAGGLSSAVGEMGAELGAEVHLEHVPCKYAGLQPWEIWL 528
Query: 349 SEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLH 408
SEAQERMV+AVP D+L AL LC A +VE T +GRFT D LRV + + +++L FLH
Sbjct: 529 SEAQERMVLAVPPDRLIALLTLCTAEEVEATPIGRFTDDKRLRVFYRDLAVVDLDMHFLH 588
Query: 409 SGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGG 468
G PQR L A + + P D AL A++ H ++ SKE I+R YDHEV GG
Sbjct: 589 EGRPQRVLNAE-WQPSPALSQSPHLTNVDPEQALLALLAHPSIASKERIIRTYDHEVGGG 647
Query: 469 TVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRN 528
TV++P G P DA V++P+ E +A+ + PR G DPY A +AIDEA+RN
Sbjct: 648 TVIKPLVGASLAGPSDATVLQPLPGE-TVGLALGFGICPRYGRHDPYWMALAAIDEALRN 706
Query: 529 AVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEY 588
VA G DPE+TAILDNFC GDP +P+ M L+ A +CY+ A+ F TPFISGKDS NNEY
Sbjct: 707 VVAVGGDPERTAILDNFCWGDPKQPDRMAGLVRAAAACYDGAVAFGTPFISGKDSLNNEY 766
Query: 589 LSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFG 648
+EG+RV+IPP+LLISA+ VPDI + D K+ G IYL+G + F GS A +
Sbjct: 767 RDAEGRRVAIPPTLLISALAEVPDIRQCVTMDVKQPGDVIYLLGATRSEFAGSHLAAVGM 826
Query: 649 IPSGESAAVPPFKKEAAE-LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE 706
I + A+P AA ++ LH I GLV +CHDLSEGGLA A EM ++G +G
Sbjct: 827 I--DDVGALPRVDLVAARTTFRTLHQAIRAGLVRACHDLSEGGLAVAAAEMAIAGELGLH 884
Query: 707 LKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
L D +L I +LF ET L+ + + +AFE G + +G G L++
Sbjct: 885 LVLD---KLDVDPITALFSETPSRFLIAVDPAHTAAFEAMFAGLPLVRLGVVTGTPALRV 941
>gi|148656743|ref|YP_001276948.1| phosphoribosylformylglycinamidine synthase II [Roseiflexus sp.
RS-1]
gi|148568853|gb|ABQ90998.1| phosphoribosylformylglycinamidine synthase II [Roseiflexus sp.
RS-1]
Length = 985
Score = 715 bits (1845), Expect = 0.0, Method: Composition-based stats.
Identities = 384/787 (48%), Positives = 505/787 (64%), Gaps = 33/787 (4%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
+DEEL+ +S +LD+ EMRAI+ +Y+ E R TD E ET+AQTWSEHC HKTFK ++
Sbjct: 165 SDEELMRISQAGVLSLDLEEMRAIQAYYRAEGREPTDGELETLAQTWSEHCSHKTFKGRV 224
Query: 62 DIDGTSLTEEQKKA-----YPGL------C-VNSIIKTYIKKATDDI-----DAPW-VLS 103
Q A YP L C ++S+I+T++ AT + D + V+S
Sbjct: 225 RYQNQVPLNPQDVALPAEHYPSLHLLSRDCEIDSLIRTFLMAATRRVLDQRRDRDFAVIS 284
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDV 163
+FVDNAGI+ FDE YE+SFK ETHNHPSA+EPFGGANTGVGGV+RDV+GVSA+P A TDV
Sbjct: 285 AFVDNAGIVAFDEHYEISFKVETHNHPSALEPFGGANTGVGGVVRDVLGVSAQPIANTDV 344
Query: 164 LCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVY 223
CFG D P + G LHP+RI +GV+ GV+DYGNK+GIPTVNG V Y Y +NPLVY
Sbjct: 345 FCFGPLDLPTTELSPGVLHPQRIAAGVVAGVRDYGNKLGIPTVNGAVFYDRGYVANPLVY 404
Query: 224 CGCAGIAPRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGE 283
CG G+APR H GD I+ +GG+TGRDG+ GATFSS + +T + GS+VQIG+
Sbjct: 405 CGTVGLAPRDTHPRAVRPGDAIVVIGGRTGRDGIHGATFSSAELTHTTAEEVGSAVQIGD 464
Query: 284 PIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAP 343
PI +KK+ +V++ ARD+GLYSAITDCGAGG SSAVGEM + G +V+LA+ P+KY GL P
Sbjct: 465 PITEKKMIDVVLQARDRGLYSAITDCGAGGLSSAVGEMGADCGAEVELARAPLKYAGLQP 524
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
WE+WLSEAQERMV+AVP LE L LC + DVE T +GR+T L VR+ +++L+
Sbjct: 525 WEIWLSEAQERMVLAVPPQCLERLLALCASEDVEATVIGRYTDTGRLVVRYNGASVVDLA 584
Query: 404 CGFLHSGPPQRKLKAAPPKDGKP----FIKYPEYKEPDLNAALKAVINHHAVNSKEDIVR 459
FLH G PQR L+A P + + D+ L A++ H + SK IVR
Sbjct: 585 MSFLHEGRPQRVLEARWDGGSLPKPQMTVHNGDQDRVDVAHLLLALLAHPNIASKAPIVR 644
Query: 460 LYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAA 519
YDHEV G TV++P G + P DAAV++P+ + + +AI +NPR GL+DPY A
Sbjct: 645 TYDHEVGGRTVVKPLVGAACDGPGDAAVLQPLPSS-VRGIAIGCGINPRYGLIDPYWMAL 703
Query: 520 SAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFIS 579
+ +DEA+RN VA GADP + AILDNFC GDP P+ M L+ A CY+ A+ + PFIS
Sbjct: 704 ACVDEALRNVVAVGADPTRAAILDNFCWGDPRLPDRMAGLVRAAAGCYDAAVAYGAPFIS 763
Query: 580 GKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFG 639
GKDS NNEY +EG+R IPP+LLISA+ +VPDI R SDFK+ G+A+YLVG + G
Sbjct: 764 GKDSLNNEYRDAEGRRTPIPPTLLISALALVPDIRRAVTSDFKEPGNAVYLVGLTRAELG 823
Query: 640 GSVFAELFG---IPSGESAAVPPFKK----EAAELYKKLHSNIMKGLVLSCHDLSEGGLA 692
GS + I S A+ + +A +L LH+ I GLV +CHDLSEGGL
Sbjct: 824 GSHLLDALPASCISPALSDALTQMPRVDLAQAPQLMAALHAAISAGLVRACHDLSEGGLG 883
Query: 693 AALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
A+ EM L+ G+ +++ H A + LF E+ LVE++ + SAFE M G
Sbjct: 884 VAVAEMALAGNLGVTLDVRAVSHNPAAADDLVLLFSESPTRFLVEVRPADASAFEAAMTG 943
Query: 750 ASIYEIG 756
+ +G
Sbjct: 944 HACARVG 950
>gi|113940519|ref|ZP_01426350.1| phosphoribosylformylglycinamidine synthase II [Herpetosiphon
aurantiacus ATCC 23779]
gi|113897836|gb|EAU16867.1| phosphoribosylformylglycinamidine synthase II [Herpetosiphon
aurantiacus ATCC 23779]
Length = 959
Score = 711 bits (1834), Expect = 0.0, Method: Composition-based stats.
Identities = 377/780 (48%), Positives = 495/780 (63%), Gaps = 26/780 (3%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
++D EL +S E AL + EM+A+R++++ R TD E ET+AQTWSEHC HKTF+A
Sbjct: 166 VSDSELERISREGILALSLAEMQAVRDYFEDLGRDPTDGELETLAQTWSEHCRHKTFRAT 225
Query: 61 IDIDGTSLTE----------EQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAG 110
I + + + A G +N ++ Y++ AT+ + +LS+FVDNAG
Sbjct: 226 ISYQQVAADQGIDAALHPALAELNAANGATINGLLNHYLRSATNAVSNEALLSAFVDNAG 285
Query: 111 IIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPD 170
I+ FDE+YE+SFK ETHNHPSA+EPFGGANTGVGGV+RDV+GVSA+P AVTDVLCFG+PD
Sbjct: 286 IVAFDEQYEISFKVETHNHPSALEPFGGANTGVGGVVRDVLGVSAKPIAVTDVLCFGYPD 345
Query: 171 TPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIA 230
P + +G LHP+RI GV+ GV+DYGNK+GIP VNG V Y Y +NPLV+CG GIA
Sbjct: 346 LPESELSQGVLHPRRIREGVVAGVRDYGNKLGIPNVNGAVWYDHGYTANPLVFCGTLGIA 405
Query: 231 PRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKV 290
PRG H AGD I+ +GG+TGRDG+ GATFSS+ + T + G++VQIG+P+ +K V
Sbjct: 406 PRGSHPRGVQAGDAIVVIGGRTGRDGIHGATFSSVELTHDTAETVGAAVQIGDPVTEKTV 465
Query: 291 AEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSE 350
+VL+ ARD GLYSAITDCGAGG SSAVGEM G V+L +P+KY GL PWE+W+SE
Sbjct: 466 IDVLLQARDLGLYSAITDCGAGGLSSAVGEMGEETGAVVELRDVPLKYAGLQPWEIWISE 525
Query: 351 AQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSG 410
AQERMV++VP ++ L LC DVE T +G FT D VL V+ + ++ L FLHSG
Sbjct: 526 AQERMVVSVPPQNVQTLLDLCRGEDVEATVIGHFTADGVLTVKHNQLTVVELDMAFLHSG 585
Query: 411 PPQRKLKA----APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQ 466
Q KL A +P +P D A LKA + V S E+IVR YDHEVQ
Sbjct: 586 GVQFKLNADWQPSPAPASQP-------ATIDHTALLKATLGQPIVASNENIVRTYDHEVQ 638
Query: 467 GGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAV 526
TVL+P G + P DA V++P + + V + LNP G +DPY A +A+DEA+
Sbjct: 639 AATVLKPLVGVNEDGPGDAGVLQP-RVDSNRGVVLGCGLNPLYGKIDPYWMALAAVDEAL 697
Query: 527 RNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNN 586
RN VAAG DPE+T ILDNFC GDP P+ + L+ + C++ AL ++TPFISGKDS NN
Sbjct: 698 RNIVAAGGDPEQTWILDNFCWGDPKLPDRLAGLVRASAGCHDAALAYRTPFISGKDSLNN 757
Query: 587 EYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAEL 646
EY +EGKRV+IPP+LLISAM +VPD+ + D K G+AIYLVG GG+V A +
Sbjct: 758 EYRDAEGKRVAIPPTLLISAMALVPDVLQTISMDAKAAGNAIYLVGLTHNERGGAVSALV 817
Query: 647 FGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGL-AAALYEMCLSGIGA 705
GI +G V A ++K LH+ I V +CHDLSEGGL AA G G
Sbjct: 818 GGIDNGNLPKVN--LATAPSVHKALHAAIRANSVRACHDLSEGGLAVAAAEMAFAGGFGL 875
Query: 706 ELKEDFHTRLGA-SKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGL 764
L+ G+ S A L+ E+T LVE+ E + FE ++ + +IG+ + L
Sbjct: 876 SLELSAMPTSGSLSADALLWSESTTRFLVEVAPEQAANFEAQLSNIAYAKIGQVLAEPRL 935
>gi|118046346|ref|ZP_01514997.1| phosphoribosylformylglycinamidine synthase II [Chloroflexus
aggregans DSM 9485]
gi|117997105|gb|EAV11295.1| phosphoribosylformylglycinamidine synthase II [Chloroflexus
aggregans DSM 9485]
Length = 973
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 383/770 (49%), Positives = 503/770 (65%), Gaps = 24/770 (3%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
+D+ELL +S + ALD+ EMRAI+ ++ + R TD E ETIAQTWSEHC HKTFKA++
Sbjct: 170 DDDELLNISQQGVLALDLAEMRAIQRYFAGQGRDPTDGELETIAQTWSEHCSHKTFKARV 229
Query: 62 DIDGTSLT-EEQKKAYPGLC--------VNSIIKTYIKKATDDIDAP----WVLSSFVDN 108
+ T +P L ++S+I+T++ +AT+ + A WVLS+FVDN
Sbjct: 230 RYEQPPETLPVNADLHPMLARLASGQMEIDSLIRTFLMRATEQVLAKRHDEWVLSAFVDN 289
Query: 109 AGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGH 168
AGI+ F YEVS+K ETHNHPSA+EPFGGANTGVGGVIRDV+GVSARP A DVLCFG
Sbjct: 290 AGIVAFGPNYEVSYKVETHNHPSALEPFGGANTGVGGVIRDVLGVSARPIANIDVLCFGM 349
Query: 169 PDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAG 228
PD A P G LHP+R+ SGV+ GV+DYGNK+GIPTV G V + Y +NPLVYCG G
Sbjct: 350 PD--APPPPPGVLHPRRVASGVVAGVRDYGNKLGIPTVGGAVLFDPGYTANPLVYCGTVG 407
Query: 229 IAPRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQK 288
IAPRG H GD I+ +GG+TGRDG+ GATFSS+ + +T GS+VQIG+PI +K
Sbjct: 408 IAPRGLHPRNVRPGDIIVVMGGRTGRDGIHGATFSSIELTHTTAVEVGSAVQIGDPITEK 467
Query: 289 KVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWL 348
K+ +VL+ ARD LYSA+TDCGAGG SSA+GEM + LG +V L ++P KY GL PWE+WL
Sbjct: 468 KMLDVLLQARDARLYSALTDCGAGGLSSAIGEMGAELGAEVHLERVPCKYAGLQPWEIWL 527
Query: 349 SEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLH 408
SEAQERMV+AVP D+L AL LC A DVE T +GRFT D LRV + + +++L FLH
Sbjct: 528 SEAQERMVLAVPPDRLVALLTLCVAEDVEATPIGRFTNDGRLRVYYHDLAVVDLEMAFLH 587
Query: 409 SGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGG 468
G PQR L+A + + P+ AAL A++ H ++ SKE I+R YDHEV GG
Sbjct: 588 EGRPQRMLEAR-WEPSPALTRSPQLDHVQPEAALLALLAHPSIASKERIIRTYDHEVGGG 646
Query: 469 TVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRN 528
TV++P G P D AV++P+ + +A+ + P G DPY A +AIDEA+RN
Sbjct: 647 TVIKPLVGAALAGPSDGAVLQPL-PDNPAGLALGFGICPHYGQHDPYWMALAAIDEALRN 705
Query: 529 AVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEY 588
VA G DP++TAILDNFC GDP +P+ M L+ A +CY+ A+ F TPFISGKDS NNEY
Sbjct: 706 VVAVGGDPDQTAILDNFCWGDPKQPDRMAGLVRAAAACYDGAVAFGTPFISGKDSLNNEY 765
Query: 589 LSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFG 648
++G+R++IPP+LLISAM V D+ + D K+ G IYL+G + F GS A +
Sbjct: 766 RDADGRRIAIPPTLLISAMAYVHDVRQCVTMDLKQAGDVIYLLGATRIEFAGSHLAAVGM 825
Query: 649 IPSGESAAVPPFKKEAAE-LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE 706
I G A+P A ++ LH I GLV +CHDLSEGGLA A EM ++G +G +
Sbjct: 826 IEDG--GALPQVDLATARATFRALHRAIRAGLVRACHDLSEGGLAVAAAEMAIAGELGLQ 883
Query: 707 LKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIG 756
L D + IA+LF E+ L+E+ +A E ++G + +G
Sbjct: 884 LNLD---TIDLDPIAALFSESPSRFLLEVDPAQTAALEAVLDGLPLVRLG 930
>gi|156741776|ref|YP_001431905.1| phosphoribosylformylglycinamidine synthase II [Roseiflexus
castenholzii DSM 13941]
gi|156233104|gb|ABU57887.1| phosphoribosylformylglycinamidine synthase II [Roseiflexus
castenholzii DSM 13941]
Length = 981
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 384/794 (48%), Positives = 507/794 (63%), Gaps = 51/794 (6%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
+D++L+ +S E +LD+ EMRAI+ +Y++E R TD E ET+AQTWSEHC HKTFK +I
Sbjct: 165 SDDDLMRISQEGILSLDLDEMRAIQAYYRSEGREPTDGELETLAQTWSEHCSHKTFKGRI 224
Query: 62 --------DIDGTSLTEEQKKAYPGLC-------VNSIIKTYIKKATDDIDAP------W 100
D D T+L E YP L ++S+I+T++ AT +
Sbjct: 225 IYKNLVPPDADDTALPAE---VYPSLHRLMRDDEIDSLIRTFLMAATRRVLEQRKSLDFA 281
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
V+S+FVDNAGI+ FD YEVSFK ETHNHPSA+EPFGGANTGVGGV+RDV+GVSA+P A
Sbjct: 282 VISAFVDNAGIVAFDNDYEVSFKVETHNHPSALEPFGGANTGVGGVVRDVLGVSAQPIAN 341
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
TDVLCFG D P+ ++ G LHP+R+ +GV+ GV+DYGNK+GIPTVNG V Y Y +NP
Sbjct: 342 TDVLCFGPLDLPSADLSPGVLHPRRVAAGVVAGVRDYGNKLGIPTVNGAVLYDRGYVANP 401
Query: 221 LVYCGCAGIAPRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQ 280
LVYCG G+APR H GD I+ +GG+TGRDG+ GATFSS + +T + GS+VQ
Sbjct: 402 LVYCGTVGLAPRDAHPRAVRPGDAIVVIGGRTGRDGIHGATFSSAELTHTTAEEVGSAVQ 461
Query: 281 IGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQG 340
IG+PI +KK+ +V++ ARD+ LYSAITDCGAGG SSAVGEM + G +VDLA+ P+KY G
Sbjct: 462 IGDPITEKKMMDVILQARDRKLYSAITDCGAGGLSSAVGEMGAECGAEVDLARAPLKYAG 521
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
L PWE+WLSEAQERMV+AVP +L L LC DVE T +GR+T L VR+ + ++
Sbjct: 522 LQPWEIWLSEAQERMVLAVPQSRLTDLLTLCAGEDVEATVIGRYTDTGRLVVRYNDMLVV 581
Query: 401 NLSCGFLHSGPPQRKLKA-----APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
+L+ FLH+G PQR L+A AP K + E + + L A++ H + SKE
Sbjct: 582 DLAMSFLHNGRPQRVLEAHWYGVAPSKQRR--TNDGHCVETEASNLLLALLAHPNIASKE 639
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
IVR YDHEV G TV++P G+ P DAAV++P+ + + +AI +NPR G +DPY
Sbjct: 640 PIVRTYDHEVGGRTVVKPLI---GDGPGDAAVLQPLPSS-MRGIAIGCGINPRYGRIDPY 695
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKT 575
A + +DEA+RN VA GADP + A+LDNFC GDP P+ M L+ A CY+ A+ +
Sbjct: 696 WMALACVDEALRNVVAVGADPARAALLDNFCWGDPRLPDRMAGLVRAAAGCYDAAVAYGA 755
Query: 576 PFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQ 635
PFISGKDS NNEY +EG+R IPP+LLISA+ +VPDI R SD K+ +++YLVG +
Sbjct: 756 PFISGKDSLNNEYRDAEGRRTPIPPTLLISALALVPDIRRAVTSDLKEVDNSVYLVGITK 815
Query: 636 FSFGGSVFAELFGI-PSGESAA--------VPPFK-KEAAELYKKLHSNIMKGLVLSCHD 685
GG A LF + P AA VP +A L LH I GLV +CHD
Sbjct: 816 AELGG---AHLFDVLPQSSIAATVSRAQTRVPRVDLVQAPHLMAALHRAIDAGLVRACHD 872
Query: 686 LSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
LSEGGL A EM L+ G+ +L+ + LF E+ LVE++ + +A
Sbjct: 873 LSEGGLGVAAAEMALAGNLGLALDLRTVPRDPDVDDDLTLLFSESPSRFLVEVRPADTAA 932
Query: 743 FEKEMEGASIYEIG 756
FE + G + IG
Sbjct: 933 FETMLAGYAHARIG 946
>gi|91200214|emb|CAJ73258.1| similar to Phosphoribosylformylglycinamidine synthase II
[Candidatus Kuenenia stuttgartiensis]
Length = 955
Score = 653 bits (1685), Expect = 0.0, Method: Composition-based stats.
Identities = 345/776 (44%), Positives = 494/776 (63%), Gaps = 38/776 (4%)
Query: 3 DEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKID 62
D +L +S E + +L+I+EMRAI++ Y T +R TD E ETIAQTWSEHCVHKT K +I+
Sbjct: 180 DVQLEKISAEGQLSLNIHEMRAIQQHYTTLRREPTDIELETIAQTWSEHCVHKTMKGRIN 239
Query: 63 IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSF 122
+G +++++K + KAT++++APW +S F DNAGIIEFDE+Y V F
Sbjct: 240 FNGK-------------IIDNLLKNTVMKATEELNAPWCVSVFKDNAGIIEFDEEYNVCF 286
Query: 123 KAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPAENVPKGT 180
K ETHNHPSAIEP+GGANTG+GGVIRD+MG + A+P TDV CFG PDTP E +PKG
Sbjct: 287 KVETHNHPSAIEPYGGANTGIGGVIRDIMGTGLGAKPILNTDVFCFGMPDTPPEKIPKGA 346
Query: 181 LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPS 240
LHPK++ GV+ GV+DYGN+MGIPTVNG +++ E Y NP+V+CG AGI P+ + +
Sbjct: 347 LHPKKVFKGVVAGVRDYGNRMGIPTVNGAIYFDERYIGNPIVFCGTAGIIPKNMCQKESR 406
Query: 241 AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQ 300
D I+ +GG+TGRDG+ GATFSS ++ + ++G +VQIG I +K + L+ A D+
Sbjct: 407 PDDLIVVVGGRTGRDGIHGATFSSAELNEQSEHMSGGAVQIGNAITEKMTLDTLLQAHDR 466
Query: 301 GLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVP 360
GLY+ ITDCGAGG SSAVGEM G V L K+P+KY+GL+ E+W+SE+QERMV++VP
Sbjct: 467 GLYNCITDCGAGGLSSAVGEMGQYTGACVYLEKVPLKYEGLSYAEIWISESQERMVLSVP 526
Query: 361 NDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAP 420
+K + L +A +VE T +G FTGD +LR+ + + + L FLH+G P+ + +A
Sbjct: 527 KEKEMEIITLFNAENVEATVIGHFTGDNMLRLYYQSEMVGELEMDFLHNGLPRLEREA-- 584
Query: 421 PKDGKPFIKYPEYKEPDL------NAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPY 474
P ++EP L LK +++ + SKE ++R YDHEVQGG+VL+P
Sbjct: 585 ------IWNAPGFEEPSLPEKENYGTDLKKLLSEWNICSKEWVIRQYDHEVQGGSVLKPL 638
Query: 475 DGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGA 534
G + + P DA++IKP+ K + +SN +NPR G +DPY AASAIDEA+R ++ G
Sbjct: 639 QGVQNDGPGDASIIKPVLWR-NKGIIVSNGMNPRYGDIDPYHMAASAIDEALRQIISVGG 697
Query: 535 DPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGK 594
+ ++ A+LDNFC G+ N+P+ + +L+ A++CY+ A+ + TPFISGKDS NNE++ +E +
Sbjct: 698 NLKRVALLDNFCWGNTNKPDRLGSLVMAAQACYDIAVAYGTPFISGKDSLNNEFI-TETE 756
Query: 595 RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGES 654
+ IPP+LLISA+ ++ D+ + K+ G+ IYLVG + GGS + + G
Sbjct: 757 TIVIPPTLLISAISVLDDVRNAVSMNAKEPGNLIYLVGVTRNELGGSHYYYIHGHKGKNV 816
Query: 655 AAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTR 714
V F + L G+V SCHD SEGGLA A EM +G G ++ +
Sbjct: 817 PVVNAF--SGKKTMNTLSIATAHGIVRSCHDCSEGGLAVAAAEMAFAG-GCGMELNLSQA 873
Query: 715 LGASKIAS----LFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
+ +I LF ET LVE+K E++ FE M+ +GK + LK+
Sbjct: 874 VVEGEITRNDTILFSETNTRFLVEVKPEHKIEFEAVMKDVPHGLLGKVRQEPCLKI 929
>gi|87311379|ref|ZP_01093500.1| phosphoribosylformylglycinamidine synthase II [Blastopirellula
marina DSM 3645]
gi|87285959|gb|EAQ77872.1| phosphoribosylformylglycinamidine synthase II [Blastopirellula
marina DSM 3645]
Length = 974
Score = 645 bits (1665), Expect = 0.0, Method: Composition-based stats.
Identities = 353/781 (45%), Positives = 483/781 (61%), Gaps = 28/781 (3%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
++D L LS E + L + EM+ I++++ R TD E E++AQTWSEHC HKT +
Sbjct: 182 LDDAGLTKLSKEGQLYLTLVEMQTIQKYFNELGRDPTDIELESVAQTWSEHCSHKTLAGR 241
Query: 61 IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSSFVDNAGIIEFD 115
I E+ ++ + N+++K I AT +I D W +S F DNAGI+ FD
Sbjct: 242 IAYK----DEKGERKF-----NNMLKETIFAATQEIRKSLGDKDWCVSVFQDNAGIVRFD 292
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPA 173
+++ + FK ETHNHPSA+EP+GGANTG+GGV+RD MG + A+P TDV CF PD
Sbjct: 293 DEHNIVFKVETHNHPSALEPYGGANTGIGGVVRDPMGTGMGAKPICNTDVFCFAPPDVDP 352
Query: 174 ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG 233
E +P G LHP+R+++GV+ GV+DYGN+MGIPTVNG V++ E Y NPLVYCG G+ P+
Sbjct: 353 ETLPPGVLHPRRVMNGVVSGVRDYGNRMGIPTVNGAVYFDERYLGNPLVYCGNVGLIPQQ 412
Query: 234 KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEV 293
+ D I++LGG+TGRDG+ GATFSS + + + ++G +VQIG I +K V +V
Sbjct: 413 HSFKEVKPNDLIVALGGRTGRDGIHGATFSSAELTSESESLSGGAVQIGNAITEKMVLDV 472
Query: 294 LIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQE 353
L++ARD+GL++A+TDCGAGG+SSAVGEM +G DV L + P+KY GL+ E+W+SEAQE
Sbjct: 473 LLEARDRGLFNAVTDCGAGGFSSAVGEMGEKIGADVWLDRAPLKYDGLSYTEIWISEAQE 532
Query: 354 RMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSG-PP 412
RMV+AVP+ K + L++LC + VE T +GRF L++ + ++ + +L FLH G PP
Sbjct: 533 RMVLAVPDHKWDELEELCSSEGVEATIIGRFAPTGRLKLFYYQEAVGDLDMKFLHDGRPP 592
Query: 413 QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLR 472
+ P KP +K P K D LK ++ V SK I+R YDHEVQGG+ ++
Sbjct: 593 IVREATYQPLPVKP-LKLPAAKSCDFAGDLKQILGSLNVASKHWIIRQYDHEVQGGSAIK 651
Query: 473 PYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAA 532
P G + P DAAV++P+ T ++ V +S +NPR G D Y A SAIDEA+RN VA
Sbjct: 652 PLVGVLNDGPGDAAVVRPVLTS-QRGVVVSCGMNPRYGDFDTYDMATSAIDEAMRNCVAV 710
Query: 533 GADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYL--- 589
GADP + AILDNFC G +RPET+ +L+ A +CY+ A+ TPFISGKDS NNE+
Sbjct: 711 GADPSQIAILDNFCWGYTDRPETLGSLVRSAIACYDMAIALGTPFISGKDSLNNEFSYFN 770
Query: 590 -SSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFG 648
+ E +R+SIPPSLLISA+G V D+ R D KK GS +Y+VGK GGS ++ +
Sbjct: 771 DAGEKQRISIPPSLLISALGQVDDVRRCVTMDLKKTGSKLYVVGKTFHELGGSHWSLIHD 830
Query: 649 IPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGL-AAALYEMCLSGIGAEL 707
P G + V A + LH I GLV +CHDLSEGGL AA G+GAEL
Sbjct: 831 QPHGAAPKVN--AAMAKSTFASLHKAIHGGLVRACHDLSEGGLAVAAAEMAFAGGLGAEL 888
Query: 708 KEDF--HTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLK 765
D H I+ LF E+ LVE+ EN F+ + G IG K L
Sbjct: 889 SLDNMPHDEAAKHPISLLFSESNTRFLVEVPAENEKQFQSVLAGIPHAAIGTVIEKPTLT 948
Query: 766 L 766
+
Sbjct: 949 I 949
>gi|57234830|ref|YP_181125.1| phosphoribosylformylglycinamidine synthase II [Dehalococcoides
ethenogenes 195]
gi|57225278|gb|AAW40335.1| phosphoribosylformylglycinamidine synthase II [Dehalococcoides
ethenogenes 195]
Length = 953
Score = 645 bits (1665), Expect = 0.0, Method: Composition-based stats.
Identities = 349/765 (45%), Positives = 486/765 (63%), Gaps = 41/765 (5%)
Query: 16 ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKA 75
+L E+ AI E Y R TDAE ET+AQTWSEHC HKTFKA +D DG
Sbjct: 189 SLSHQELSAIYEHYLKLGRAPTDAELETLAQTWSEHCCHKTFKAMLDYDGQ--------- 239
Query: 76 YPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEP 135
+N+++K I KAT +++ PW LS FVDN+G+IEFD+K+ V FKAETHNHPSA+EP
Sbjct: 240 ----IINNLLKQTIAKATAELNKPWCLSVFVDNSGVIEFDDKWGVCFKAETHNHPSAVEP 295
Query: 136 FGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEG 193
+GGA TG+GGVIRD++G ++A+P A TDV CFG PD P +P G LHP+R+ GV G
Sbjct: 296 YGGAATGIGGVIRDILGTGLAAKPIANTDVFCFGQPDLPENELPPGVLHPRRVFKGVRSG 355
Query: 194 VKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRT-KPSAGDHIISLGGKT 252
V DYGN+MGIPTVNG V + E Y +NPLVYCG G+ P+ K SAGD ++ +GG+T
Sbjct: 356 VADYGNRMGIPTVNGAVLFDERYTANPLVYCGTIGLIPKKYALPGKQSAGDLVVLIGGRT 415
Query: 253 GRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAG 312
GRDG+ G TF+S ++ + +++ ++VQIG PI++K++ + L+ ARD+ L+ ITDCG G
Sbjct: 416 GRDGIHGVTFASGELNDRSTELSFTAVQIGNPIVEKRMLDTLLAARDRELFVRITDCGGG 475
Query: 313 GYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCD 372
G SSA+GEMA + G V L K+P+KY GL E+W+SE+QERM++AV +KL + L +
Sbjct: 476 GLSSAIGEMAESTGVKVYLDKVPLKYSGLTYSEIWISESQERMLLAVKKEKLSEIMALFE 535
Query: 373 ANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKY-- 430
+ VE + +G F+ D L++ + + + +L FLH+G PQ +L A K P +
Sbjct: 536 SEGVEASVIGEFSNDRHLKLFYEDNPVADLQMDFLHNGRPQLELTATRHKHRHPEADFDC 595
Query: 431 PEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKP 490
PE DL LK +++H V S+E I+R YDHEVQGG+VL+P G E + P DAAVI+P
Sbjct: 596 PE----DLETELKNILSHWNVCSREWIIRQYDHEVQGGSVLKPMAGAENDGPGDAAVIRP 651
Query: 491 METEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP 550
+ KKAV ISN +NP +D Y AASAIDEA+R +A G + ++ A+LDNF G+
Sbjct: 652 V-LGSKKAVVISNGINPSYADVDAYNMAASAIDEALRQIIAVGGNLDRVALLDNFSWGNA 710
Query: 551 NRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIV 610
+RPE++ L+ ++C++ +LVF+TPFISGKDS NNE+ ++ K ++IP +LLISA+G++
Sbjct: 711 SRPESLGDLVRACQACHDLSLVFETPFISGKDSLNNEFRYND-KLITIPHTLLISAIGVM 769
Query: 611 PDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK 670
D + DFKK G+ IYLVGK GGS + + + AV + A E +
Sbjct: 770 EDGEKAVSMDFKKAGNLIYLVGKTAEELGGSHYFKNHSFIGNRAPAVN--AERAKENMQA 827
Query: 671 LHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIAS------- 722
L S KGLV +CHDLSEGGL A EM SG +GA + RL ++
Sbjct: 828 LSSATAKGLVAACHDLSEGGLGVAAAEMAFSGKLGANI------RLADVPLSEKIEREDY 881
Query: 723 -LFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
LF E+ L E+ E+++ FEK M+ IG+ + LK+
Sbjct: 882 ILFSESNSRFLAEVSPEHKAEFEKLMQAGDFGLIGEVTAEPRLKI 926
>gi|73748224|ref|YP_307463.1| phosphoribosylformylglycinamidine synthase II [Dehalococcoides sp.
CBDB1]
gi|73659940|emb|CAI82547.1| phosphoribosylformylglycinamidine synthase II [Dehalococcoides sp.
CBDB1]
Length = 953
Score = 633 bits (1632), Expect = e-179, Method: Composition-based stats.
Identities = 342/766 (44%), Positives = 480/766 (62%), Gaps = 37/766 (4%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
+ +L E+ I E Y R TDAE ET+AQTWSEHC HKTFKA +D DG
Sbjct: 186 KEYSLSHQELSVIYEHYLKLGRAPTDAELETLAQTWSEHCCHKTFKAMLDYDGQ------ 239
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
+N+++K I KAT +++ PW LS FVDN+G+IEF++++ V FKAETHNHPSA
Sbjct: 240 -------IINNLLKQTIAKATAELNKPWCLSVFVDNSGVIEFNDEWGVCFKAETHNHPSA 292
Query: 133 IEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+EP+GGA TG+GGVIRD++G ++A+P A TDV CFG PD + +P G LHP+R+ GV
Sbjct: 293 VEPYGGAATGIGGVIRDILGTGLAAKPIANTDVFCFGPPDLAEDKLPPGVLHPRRVFKGV 352
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRT-KPSAGDHIISLG 249
GV DYGN+MGIPTVNG V + E Y +NPLVYCG G+ P+ K SAGD ++ +G
Sbjct: 353 RSGVADYGNRMGIPTVNGAVLFDERYTANPLVYCGTIGLIPKKYALPGKQSAGDLVVLIG 412
Query: 250 GKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDC 309
G+TGRDG+ G TF+S ++ + +++ ++VQIG I++K++ + L+ ARD+ L+ ITDC
Sbjct: 413 GRTGRDGIHGVTFASGELNDRSTELSFTAVQIGNAIVEKRMLDTLLQARDRELFVRITDC 472
Query: 310 GAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQK 369
G GG SSAVGEMA + G + L K+P+KY GL E+W+SE+QERM++AV +KL +
Sbjct: 473 GGGGLSSAVGEMAESTGVKIYLDKVPLKYSGLTYSEIWISESQERMLLAVNKEKLGEILA 532
Query: 370 LCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIK 429
L ++ VE + +G FT D L++ + + ++ +L FLH+G PQ +L+A K P
Sbjct: 533 LFESEGVEASVIGEFTSDRHLKLFYQDHQVADLQMNFLHNGRPQLELRATHHKTRHPEAD 592
Query: 430 YPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
+ K D LK +++H V S+E I+R YDHEVQGG+VL+ G E + P DAAVI+
Sbjct: 593 FDCPK--DFETELKNILSHWNVCSREWIIRQYDHEVQGGSVLKAMVGAENDGPGDAAVIR 650
Query: 490 PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD 549
P+ KKAV ISN +NP +D Y AASAIDEA+R +A G + E+ A+LDNF G+
Sbjct: 651 PV-LGSKKAVVISNGINPSYADVDAYNMAASAIDEALRQIIAVGGNLERVALLDNFSWGN 709
Query: 550 PNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
+RPE++ L+ ++C++ +LVF TPFISGKDS NNE+ E K ++IP +LLISA+G+
Sbjct: 710 ASRPESLGDLVHACQACHDLSLVFGTPFISGKDSLNNEF-RYEDKLITIPHTLLISAIGV 768
Query: 610 VPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYK 669
+ D + DFKK G+ IY+VGK GGS + + + AV K A E +
Sbjct: 769 MEDGDKAISMDFKKSGNLIYIVGKTAEELGGSHYFKNHSFIGNRAPAVN--AKRAKENMQ 826
Query: 670 KLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIAS------ 722
L GLV +CHDLSEGGL EM SG +GA H RL +A
Sbjct: 827 ALSCATAGGLVAACHDLSEGGLGVTAAEMAFSGKLGA------HIRLADVPLAEKIERED 880
Query: 723 --LFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
LF E+ LVE+ ++++ FEK M G +G+ + L++
Sbjct: 881 YILFSESNSRFLVEVAPKHQAEFEKLMSGCDFGLVGEVMSEPSLEI 926
>gi|147669006|ref|YP_001213824.1| phosphoribosylformylglycinamidine synthase II [Dehalococcoides sp.
BAV1]
gi|146269954|gb|ABQ16946.1| phosphoribosylformylglycinamidine synthase II [Dehalococcoides sp.
BAV1]
Length = 953
Score = 631 bits (1628), Expect = e-179, Method: Composition-based stats.
Identities = 342/766 (44%), Positives = 478/766 (62%), Gaps = 37/766 (4%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
+ +L E+ I E Y R TDAE ET+AQTWSEHC HKTFKA +D DG
Sbjct: 186 KEYSLSHQELSVIYEHYLKLGRAPTDAELETLAQTWSEHCCHKTFKAMLDYDGQ------ 239
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
+N+++K I KAT +++ PW LS FVDN+G+IEFD+++ V FKAETHNHPSA
Sbjct: 240 -------IINNLLKQTIAKATAELNKPWCLSVFVDNSGVIEFDDEWGVCFKAETHNHPSA 292
Query: 133 IEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+EP+GGA TG+GGVIRD++G ++A+P A TDV CFG PD + +P G LHP+R+ GV
Sbjct: 293 VEPYGGAATGIGGVIRDILGTGLAAKPIANTDVFCFGPPDLAEDKLPPGVLHPRRVFKGV 352
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRT-KPSAGDHIISLG 249
GV DYGN+MGIPTVNG V + E Y +NPLVYCG G+ P+ K S GD ++ +G
Sbjct: 353 RSGVADYGNRMGIPTVNGAVLFDERYTANPLVYCGTIGLIPKKYALPGKQSTGDLVVLIG 412
Query: 250 GKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDC 309
G+TGRDG+ G TF+S ++ + +++ ++VQIG I++K++ + L+ ARD+ L+ ITDC
Sbjct: 413 GRTGRDGIHGVTFASGELNDRSTELSFTAVQIGNAIVEKRMLDTLLQARDRELFVRITDC 472
Query: 310 GAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQK 369
G GG SSAVGEMA + G + L K+P+KY GL E+W+SE+QERM++AV +KL +
Sbjct: 473 GGGGLSSAVGEMAESTGVKIYLDKVPLKYSGLTYSEIWISESQERMLLAVNKEKLGEILA 532
Query: 370 LCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIK 429
L + VE + +G FT D L++ + + ++ +L FLH+G PQ +L+A K P
Sbjct: 533 LFENEGVEASVIGEFTSDRHLKLFYQDHQVADLQMNFLHNGRPQLELRATHHKTRHPEAD 592
Query: 430 YPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
+ K D LK +++H V S+E I+R YDHEVQGG+VL+ G E + P DAAVI+
Sbjct: 593 FDCPK--DFETELKNILSHWNVCSREWIIRQYDHEVQGGSVLKAMVGAENDGPGDAAVIR 650
Query: 490 PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD 549
P+ KKAV ISN +NP +D Y AASAIDEA+R +A G + E+ A+LDNF G+
Sbjct: 651 PV-LGSKKAVVISNGINPSYADVDAYNMAASAIDEALRQIIAVGGNLERVALLDNFSWGN 709
Query: 550 PNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
+RPE++ L+ ++C++ +LVF TPFISGKDS NNE+ E K ++IP +LLISA+G+
Sbjct: 710 ASRPESLGDLVHACQACHDLSLVFGTPFISGKDSLNNEF-RYEDKLITIPHTLLISAIGV 768
Query: 610 VPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYK 669
+ D + DFKK G+ IY+VGK GGS + + + AV K A E +
Sbjct: 769 MEDGDKAISMDFKKSGNLIYIVGKTAEELGGSHYFKNHRFIGNRAPAVN--AKRAKENMQ 826
Query: 670 KLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIAS------ 722
L GLV +CHDLSEGGL EM SG +GA H RL +A
Sbjct: 827 ALSCATAGGLVAACHDLSEGGLGVTAAEMAFSGKLGA------HIRLADVPLAEKIERED 880
Query: 723 --LFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
LF E+ LVE+ ++++ FEK M G +G+ + L++
Sbjct: 881 YILFSESNSRFLVEVAPKHQAEFEKLMSGCDFGLVGEVMSEPSLEI 926
>gi|32473676|ref|NP_866670.1| phosphoribosylformylglycinamidine synthase II [Rhodopirellula
baltica SH 1]
gi|32444212|emb|CAD74209.1| phosphoribosylformylglycinamidine synthase II [Rhodopirellula
baltica SH 1]
Length = 1009
Score = 614 bits (1584), Expect = e-174, Method: Composition-based stats.
Identities = 348/776 (44%), Positives = 470/776 (60%), Gaps = 44/776 (5%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
++D L LS E + L + EM+ IR+ + R TD E E++AQTWSEHC HKT +
Sbjct: 199 LDDAGLEKLSKEGQLYLTLVEMQTIRDHFVELGRDPTDIELESVAQTWSEHCSHKTLAGR 258
Query: 61 ID-----IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSSFVDNAG 110
I DGT +E++ N+++K I +AT I D W +S F DNAG
Sbjct: 259 IHYKGPGADGTPGGDERQ-------YNNMLKETIFEATQTIRRSLGDDDWCVSVFKDNAG 311
Query: 111 IIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGH 168
I+ FDE+ V FK ETHNHPSA+EP+GGANTG+GGVIRD MG + A+P TDV CF
Sbjct: 312 IVTFDEQDHVCFKVETHNHPSALEPYGGANTGIGGVIRDPMGTGMGAKPVCNTDVFCFAP 371
Query: 169 PDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAG 228
PD E +P G LHP+R+I GV+ GV+DYGN+MGIPTVNG V++ E Y NPLVYCG G
Sbjct: 372 PDVSPEELPPGVLHPRRVIQGVVSGVRDYGNRMGIPTVNGAVYFDERYLGNPLVYCGNVG 431
Query: 229 IAPRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQK 288
I P G + D I+++GG+TGRDG+ GATFSS + + + ++G +VQIG I +K
Sbjct: 432 IIPVGMEDKEVKPNDLIVAVGGRTGRDGIHGATFSSAELTSESESLSGGAVQIGNAITEK 491
Query: 289 KVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWL 348
V +VL+ ARD+GLY+A+TDCGAGG+SSAVGEM LG +V L K P+KY GL E+W+
Sbjct: 492 MVLDVLMQARDRGLYNAVTDCGAGGFSSAVGEMGEELGAEVWLDKAPLKYDGLTYTEIWI 551
Query: 349 SEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLH 408
SEAQERMV+AVP ++ + L++LC++ VE +GRF L++ F + + +++ FLH
Sbjct: 552 SEAQERMVLAVPQERWDELRELCESEGVEAAAIGRFVPTGRLQLNFHGQTVGDVAMSFLH 611
Query: 409 SGPPQ--RKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQ 466
G P R PPK KP + LK ++ + V SK ++R YDHEVQ
Sbjct: 612 DGRPPVIRDAIYEPPK-AKPLSIGDRDAAANSETLLK-ILGSYNVASKHWVIRQYDHEVQ 669
Query: 467 GGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAV 526
G+V++P GP+ + P DAAV++P + ++ + IS +NP G D Y AASAIDEA+
Sbjct: 670 AGSVVKPLVGPQCDGPGDAAVVRP-KLNSRRGLVISCGMNPHYGDFDTYHMAASAIDEAM 728
Query: 527 RNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNN 586
RNAVA GADP K AILDNFC G +R ET+ +L+ A +C + A+ TPF+SGKDS NN
Sbjct: 729 RNAVAVGADPSKIAILDNFCWGYTDRAETLGSLVRAAIACQDLAVTLGTPFVSGKDSLNN 788
Query: 587 EYL----SSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSV 642
E+ +E + ++IPPSLLISAMG + D+ + D K+ G+ I+LVG+ GGS
Sbjct: 789 EFSYFDDKNEKQTIAIPPSLLISAMGQIDDVSKSITMDAKEAGNVIFLVGETHRELGGSH 848
Query: 643 FAELFGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS 701
+ + P G AVP K A + + +H I LV SCHDL EGGLA A EM L+
Sbjct: 849 YGLVENEPGG---AVPEVDAKLAKKTFATVHQAIQSRLVRSCHDLCEGGLAVAAVEMALA 905
Query: 702 -GIGAEL-----------KEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK 745
G+G L + T S LF E+ L+E E+ A K
Sbjct: 906 GGLGMNLDLATVSREQPSNDGVLTAAALSATEVLFSESNTRFLIECAPESAEALSK 961
>gi|149175437|ref|ZP_01854058.1| phosphoribosylformylglycinamidine synthase II [Planctomyces maris
DSM 8797]
gi|148845705|gb|EDL60047.1| phosphoribosylformylglycinamidine synthase II [Planctomyces maris
DSM 8797]
Length = 971
Score = 608 bits (1567), Expect = e-172, Method: Composition-based stats.
Identities = 344/787 (43%), Positives = 480/787 (60%), Gaps = 54/787 (6%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
MND++L LS E + L++ EM+ I+ +Y ++K+ TD E E+IAQTWSEHC HKT +
Sbjct: 179 MNDKQLETLSREGQLYLNLTEMKTIKAYYVSQKKDPTDVELESIAQTWSEHCSHKTLAGR 238
Query: 61 IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSSFVDNAGIIEFD 115
I K L +++K I AT +I D W +S F DNAG+I FD
Sbjct: 239 IHF---------KDGERDLHFENMLKETIFAATTEIRKSLGDKDWCVSVFADNAGVITFD 289
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPA 173
+K +V FK ETHNHPSA+EP+GGANTG+GGVIRD +G + RP TDV CF PD P
Sbjct: 290 DKQDVCFKVETHNHPSALEPYGGANTGLGGVIRDPLGTGLGGRPVCNTDVFCFAPPDIPY 349
Query: 174 ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG 233
+P G LHPK + +GV+ GV+DYGN+MGIPTVNG V++ E Y NPLVYCG + P G
Sbjct: 350 AELPAGVLHPKAVATGVVSGVRDYGNRMGIPTVNGAVYFDERYLGNPLVYCGNVAMLPVG 409
Query: 234 K-HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAE 292
K + + G +I+++GG+TGRDG+ GATFSS + + + ++G +VQIG I +K + +
Sbjct: 410 KSEKQQAQPGHYIVAVGGRTGRDGIHGATFSSAELTSESEMLSGGAVQIGNAITEKMMMD 469
Query: 293 VLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQ 352
V+++ARD+ L+SAITDCGAGG+SSAVGEM G +V L + P+KY GL+ E+W+SEAQ
Sbjct: 470 VILEARDKELFSAITDCGAGGFSSAVGEMGEKTGAEVWLDQCPLKYAGLSYTEIWISEAQ 529
Query: 353 ERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP 412
ERMV+AVP + EA +K+C VE + +G+FT + L +++ ++ + +L FLH G P
Sbjct: 530 ERMVLAVPPENWEAFEKICAGEGVEASVIGKFTDTSHLVLKYQDQVVADLEMSFLHDGRP 589
Query: 413 QRKLKAAPPKDGKPFIKYPEYKEP-----------DLNAALKAVINHHAVNSKEDIVRLY 461
P ++ YK P + L ++++ V SKE I+R Y
Sbjct: 590 -------------PVVREAVYKIPAFTPLTPPQRDNYTKDLTSILSSLNVCSKEWIIRQY 636
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASA 521
D EVQ G+V++P G + + P DAAV++P + + + IS +NPR G L+ + AASA
Sbjct: 637 DQEVQAGSVVKPLVGVQNDGPSDAAVVRP-DLTSTRGLVISCGMNPRYGDLNTHWMAASA 695
Query: 522 IDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGK 581
IDEA+RN VA GADP K AILDNFC G+ +RPET+ +L+ A +C ++ + +PFISGK
Sbjct: 696 IDEAIRNCVAVGADPAKIAILDNFCWGNTDRPETLGSLVAAALACKEFSIAYGSPFISGK 755
Query: 582 DSFNNEYL----SSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFS 637
DS NE+ E + V+IP SLLISA+G + D+ D K G+ I++VG
Sbjct: 756 DSLYNEFSFENEQGEKETVAIPASLLISAIGQIADVSHAVTMDVKAPGNRIFMVGTTHDE 815
Query: 638 FGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
GGS FA + + G+ V K+EA EL+K LH I K L+ SCHDLSEGGLA A E
Sbjct: 816 LGGSHFALVNDLEGGQVPQVD--KEEAPELFKALHLAIQKQLIRSCHDLSEGGLAVAAAE 873
Query: 698 MCLSGIGAELKEDFHTRLGA----SKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIY 753
M +G G +K D TRL S + LF E+ L+E+ + A + +
Sbjct: 874 MAFAG-GYGMKLD-PTRLPEALELSTPSLLFSESNTRFLLEVPLDQIDALYECFGELPLV 931
Query: 754 EIGKTCG 760
EIG+ G
Sbjct: 932 EIGEVIG 938
>gi|147677764|ref|YP_001211979.1| phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Pelotomaculum thermopropionicum SI]
gi|146273861|dbj|BAF59610.1| phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Pelotomaculum thermopropionicum SI]
Length = 944
Score = 571 bits (1471), Expect = e-161, Method: Composition-based stats.
Identities = 327/749 (43%), Positives = 449/749 (59%), Gaps = 48/749 (6%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
M+DEEL+ LS ++ L + EM+ I+ ++ +R TD E ETIAQTWSEHCVHKTFKA+
Sbjct: 173 MSDEELIELSRDK-LFLSLEEMKVIQNYFTGIQRDPTDCEIETIAQTWSEHCVHKTFKAR 231
Query: 61 IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEV 120
+ +DG K+ +K AT++I P VLS+FVDN+G++EF + +
Sbjct: 232 LVVDGIEKKPLLKR--------------LKDATEEISHPLVLSAFVDNSGVMEFYDGMAI 277
Query: 121 SFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDTPAENVPK 178
K ETHN PSAIEP+GGA TG GGV RD++G A+ A TD+ CF P TP E++P
Sbjct: 278 CGKVETHNSPSAIEPYGGAMTGSGGVFRDIVGTGQGAKVVASTDMFCFAPPHTPREHIPP 337
Query: 179 GTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPR-GKHRT 237
G LHP ++ V+ GV+DYGN+MGIPT NG VH+H + + P V G GI P G +
Sbjct: 338 GCLHPHYLLRRVVAGVRDYGNRMGIPTNNGSVHFHRDFRAKPSVIVGAYGILPAAGCRKG 397
Query: 238 KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDA 297
KP AGD +++LGG+TGRDG+ GATFSS M T +V S+VQIG PI +K++ + ++ A
Sbjct: 398 KPEAGDLVVALGGRTGRDGIHGATFSSGEMTDRTIEVNSSAVQIGHPIEEKRMFDAILAA 457
Query: 298 RDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVI 357
RD+GL AITDCGAGG++SAVGEM S G + L + P+KY GL+PWE+ LSE+QERM++
Sbjct: 458 RDEGLIRAITDCGAGGFASAVGEMGSETGARIALDRAPLKYTGLSPWEILLSESQERMIL 517
Query: 358 AVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLK 417
AV + + L ++C +VE T LG FTGD + + ++NL FLH+G PQR LK
Sbjct: 518 AVAPEHVNRLFEICRGYNVEATVLGEFTGDHYFTATYEGRVVMNLDMEFLHNGLPQRLLK 577
Query: 418 AAPPKDGKPFIKYPEYKEP------DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVL 471
A+ K P + EP + + V++H V SKE IVRLYDH VQG L
Sbjct: 578 AS--------WKRPCHAEPGEATTVNWSGLYSQVLSHLNVCSKEPIVRLYDHGVQGTNAL 629
Query: 472 RPYDGPEGNVPQDAAVIKPMETEGKK-AVAISNALNPRQGLLDPYAAAASAIDEAVRNAV 530
P+ G G+ P DA ++ P+ GK + IS+ LNP +DPY + A EA NAV
Sbjct: 630 PPFGGINGDGPNDAVILTPI--LGKPYGMIISHGLNPVLNTIDPYYGSLWAATEAASNAV 687
Query: 531 AAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLS 590
A GA+P + ++DNF P+ E + AL +C + A PFISGKDS ++ Y
Sbjct: 688 ACGANPNEMVLIDNFIWPFPDE-ELLGALDMAVDACVDFARATGMPFISGKDSLSSTYRG 746
Query: 591 SEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVG-KPQFSFGGSVFAELFGI 649
+G + IPP L ISA G +PD+ R +DFK+ GS I LVG + GSV+ E+ G
Sbjct: 747 KDGTVIKIPPVLCISAFGRIPDVSRSVSTDFKETGSHIVLVGYRNPNEMAGSVYYEILGA 806
Query: 650 PSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELK 708
+ + ++ + ++ I G +L+CHD+SEGGLAA+L EMC G IGA +
Sbjct: 807 TGNNLPRIN--MRLLKKVLETVYGAINSGKLLACHDISEGGLAASLAEMCFGGDIGAAI- 863
Query: 709 EDFHTRLGASKIAS--LFGETTGCLLVEI 735
R+ + A F ET GC L E+
Sbjct: 864 -----RIPGDEKAENFFFNETAGCFLAEV 887
>gi|94986959|ref|YP_594892.1| phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lawsonia intracellularis PHE/MN1-00]
gi|94731208|emb|CAJ54570.1| phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lawsonia intracellularis PHE/MN1-00]
Length = 992
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 325/791 (41%), Positives = 453/791 (57%), Gaps = 59/791 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFY-----KTEKRPC------TDAEFETIAQTWS 49
MND LL S ER AL + EM+ I+ ++ K E+ TD E E +AQTWS
Sbjct: 186 MNDAMLLHASKERTLALSLEEMQVIQRWFMQPEVKKERVAIGLTPDPTDVEIEMLAQTWS 245
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC HK F A+I ++ +NS+ KTYI+ TD I D + LS
Sbjct: 246 EHCKHKIFAAQISYKDLEQNSQE-------VINSLYKTYIQNTTDIIRAQLGDKDFCLSV 298
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DNAG++ F++ ++V K ETHN PSA++P+GGA TG+ GV RD MG + A TD
Sbjct: 299 FKDNAGVVAFNDTHDVCIKVETHNSPSALDPYGGALTGIVGVNRDPMGTGLGAELVCNTD 358
Query: 163 VLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLV 222
V CF P E +P LHP+RI GV EGV+ GNK GIPT+NG + + + + PLV
Sbjct: 359 VFCFASP-FHREPLPPRLLHPRRIFEGVREGVEHGGNKSGIPTINGSIVFDDRFLGKPLV 417
Query: 223 YCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
+CG GI P + + K + GD+II +GG+ G+DG+ GATFSS + + A
Sbjct: 418 FCGTIGIIPCIINNKKGYEKKANVGDYIIMVGGRIGKDGIHGATFSSEELHEQSPVTA-- 475
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIPV 336
VQIG+PI Q+K+ + ++ RD GLYSAITD GAGG SS++GEMA G C +DL+K +
Sbjct: 476 -VQIGDPITQRKMYDFILHVRDLGLYSAITDNGAGGLSSSIGEMAQDTGGCHIDLSKALL 534
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ LSEAQERM IAVP + ++ L + VE++ LG FT +G
Sbjct: 535 KYDGLCPWEILLSEAQERMTIAVPKENIQKLSSIAKHMGVEISILGEFTNSGYFHATYGS 594
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYP----EYKEPDLNAALKAVINHHAVN 452
K + L+ FLH G PQ L A + KP+ YP E D + L ++ +
Sbjct: 595 KTVAYLNMEFLHHGVPQLTLNA---QWEKPY--YPNNRIESVGIDQSMFLHTMLGRLNIC 649
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
SKE ++R YDHEV+GG+V++P G + + P DA V++P+ + + IS+ + P+
Sbjct: 650 SKEYVIRQYDHEVRGGSVIKPLMGVKQDAPMDAGVLRPI-LNSETGLVISHGICPKFSDY 708
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMARSCYN 568
D Y A+AIDE +RNAVA GADP++ A +DNFC DP P+ ++ L ++ R+C
Sbjct: 709 DTYWMVANAIDEGIRNAVAVGADPDRMAGVDNFCWCDPIQSEKTPDGLYKLAQLVRACKA 768
Query: 569 TA---LVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEG 625
+ L + P ISGKDS N+Y+ G ++SIPP+LL S +GI+ DI + SDFKK G
Sbjct: 769 LSTFCLHYGVPCISGKDSMKNDYIGG-GIKISIPPTLLFSVLGIIDDINKAITSDFKKPG 827
Query: 626 SAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKK-EAAELYKKLHSNIMKGLVLSCH 684
IY+VG GS A I ++VP +A Y+K++S I K + SCH
Sbjct: 828 DHIYIVGDTACELAGSELASELHI---SCSSVPQVHAIQAKSNYRKIYSAIQKKYITSCH 884
Query: 685 DLSEGGLAAALYEMCLSG-IGAELKED-FHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
DLS+GG A AL EMC+ G IG ++ D T S L+ ET LL+ + +N +
Sbjct: 885 DLSDGGFAVALAEMCIGGRIGCHVELDRIPTIENLSVTELLYSETASRLLLTVSPDNIAP 944
Query: 743 FEKEMEGASIY 753
FE+ M G++ Y
Sbjct: 945 FEQLMGGSAKY 955
>gi|120601257|ref|YP_965657.1| Phosphoribosylformylglycinamidine synthase [Desulfovibrio vulgaris
subsp. vulgaris DP4]
gi|120561486|gb|ABM27230.1| Phosphoribosylformylglycinamidine synthase [Desulfovibrio vulgaris
subsp. vulgaris DP4]
Length = 993
Score = 545 bits (1405), Expect = e-153, Method: Composition-based stats.
Identities = 313/736 (42%), Positives = 437/736 (59%), Gaps = 53/736 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYK---------TEKRPC--TDAEFETIAQTWS 49
M+D+EL+A S AL + EM AIR +Y+ E P TDAE E +AQTWS
Sbjct: 186 MSDDELMAFSRANTLALSLEEMHAIRAYYQRDDVRAARAAEGLPADPTDAEVEALAQTWS 245
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC HK F ++ID + + ++S+ K+ I+ T I D + S
Sbjct: 246 EHCKHKIFSSRIDYENRETGRRET-------IDSLFKSCIQDTTKTIRARLGDKDFCRSV 298
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DNAG+I F++ +++ K ETHN PSA++P+GGA TG+ GV RD MG + A TD
Sbjct: 299 FKDNAGVIAFNDTHDICIKVETHNSPSALDPYGGALTGIVGVNRDPMGTGMGANLVCNTD 358
Query: 163 VLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLV 222
V CF P E +P LHP+R++ GV EGV+ GNK GIPTVNG + + + Y PLV
Sbjct: 359 VFCFASPFWEGE-LPPRLLHPRRVLEGVREGVEHGGNKSGIPTVNGSIVFEDRYLGKPLV 417
Query: 223 YCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
YCG G+ P + + + GD I+ +GG+ G+DG+ GATFSS + + +
Sbjct: 418 YCGTVGMIPAQVAGKPGYTKEARPGDAIVMVGGRIGKDGIHGATFSSEELHEGS---PAT 474
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIPV 336
+VQIG+PI Q+K+ + ++ ARD GLY+AITD GAGG SS+VGEMA G C +DLA+ P+
Sbjct: 475 AVQIGDPITQRKMYDCIMRARDMGLYTAITDNGAGGLSSSVGEMAQDTGGCRLDLARAPL 534
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ LSEAQERM +AVP DKLEA +L DVE T LG FT + FG+
Sbjct: 535 KYDGLRPWEILLSEAQERMTLAVPQDKLEAFMRLASEMDVEATVLGEFTDSGYFHITFGD 594
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKP--FIKYPEYKEPDLNAALKAVINHHAVNSK 454
+++ L FLH G PQ +LKA + P I PE ++ A L+ ++ + SK
Sbjct: 595 RQVAYLDMDFLHDGVPQLQLKAVWERPAHPEGRIDLPEEEQ---GAFLRRMMGSLNICSK 651
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E ++R YDHEV+GG+V++P G + + P DAAV++P+ + + + +S+ + P+ D
Sbjct: 652 EYVIRQYDHEVKGGSVVKPLVGVKRDGPADAAVVRPL-LDSESGIVLSHGICPKFSDYDA 710
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMA---RSCY 567
Y A+AIDEAVRNAVA G DP+ + +DNFC DP P+ + L ++ R+
Sbjct: 711 YWMMANAIDEAVRNAVAVGGDPDFMSGVDNFCWCDPVQSDKTPDGHYKLAQLVRANRALE 770
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ L + P +SGKDS N+Y + G ++SIPP++L S MG++ D+ R SDFK+ G
Sbjct: 771 HFCLAYGVPCVSGKDSMKNDY-TGGGTKISIPPTVLFSVMGVIDDVNRTVTSDFKRAGER 829
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAA-ELYKKLHSNIMKGLVLSCHDL 686
IYL+G + GS A++ GI A VP AA Y+ L+ I GLV +CHDL
Sbjct: 830 IYLLGLTRREMAGSEAAQVLGI---SCADVPQVDAPAALARYRALYGAIRAGLVTACHDL 886
Query: 687 SEGGLAAALYEMCLSG 702
S+GGLA AL EMCL G
Sbjct: 887 SDGGLAVALAEMCLGG 902
>gi|46581583|ref|YP_012391.1| phosphoribosylformylglycinamidine synthase II [Desulfovibrio
vulgaris subsp. vulgaris str. Hildenborough]
gi|46451006|gb|AAS97651.1| phosphoribosylformylglycinamidine synthase II [Desulfovibrio
vulgaris subsp. vulgaris str. Hildenborough]
Length = 816
Score = 543 bits (1398), Expect = e-152, Method: Composition-based stats.
Identities = 312/736 (42%), Positives = 436/736 (59%), Gaps = 53/736 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYK---------TEKRPC--TDAEFETIAQTWS 49
M+D+EL+A S AL + EM AIR +Y+ E P TDAE E +AQTWS
Sbjct: 9 MSDDELMAFSRANTLALSLEEMHAIRAYYQRDDVRAARAAEGLPADPTDAEVEALAQTWS 68
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC HK F ++ID + + ++S+ K+ I+ T I D + S
Sbjct: 69 EHCKHKIFSSRIDYENRETGRRET-------IDSLFKSCIQDTTKTIRARLGDKDFCRSV 121
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DNAG+I F++ +++ K ETHN PSA++P+GGA TG+ GV RD MG + A TD
Sbjct: 122 FKDNAGVIAFNDTHDICIKVETHNSPSALDPYGGALTGIVGVNRDPMGTGMGANLVCNTD 181
Query: 163 VLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLV 222
V CF P E +P LHP+R++ GV EGV+ GNK GIPTVNG + + + Y PLV
Sbjct: 182 VFCFASPFWEGE-LPPRLLHPRRVLEGVREGVEHGGNKSGIPTVNGSIVFEDRYLGKPLV 240
Query: 223 YCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
YCG G+ P + + + GD I+ +GG+ G+DG+ GATFSS + + +
Sbjct: 241 YCGTVGMIPAQVAGKPGYTKEARPGDAIVMVGGRIGKDGIHGATFSSEELHEGS---PAT 297
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIPV 336
+VQIG+PI Q+K+ + ++ ARD GLY+AITD GAGG SS+VGEMA G C +DLA+ P+
Sbjct: 298 AVQIGDPITQRKMYDCIMRARDMGLYTAITDNGAGGLSSSVGEMAQDTGGCRLDLARAPL 357
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ LSEAQERM +AVP DKLEA +L DVE T LG FT + FG+
Sbjct: 358 KYDGLRPWEILLSEAQERMTLAVPQDKLEAFMRLASEMDVEATVLGEFTDSGYFHITFGD 417
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKP--FIKYPEYKEPDLNAALKAVINHHAVNSK 454
+++ L FLH G PQ +LKA + P I PE ++ L+ ++ + SK
Sbjct: 418 RQVAYLDMDFLHDGVPQLQLKAVWERPAHPEGRIDLPEEEQGPF---LRRMMGSLNICSK 474
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E ++R YDHEV+GG+V++P G + + P DAAV++P+ + + + +S+ + P+ D
Sbjct: 475 EYVIRQYDHEVKGGSVVKPLVGVKRDGPADAAVVRPL-LDSESGIVLSHGICPKFSDYDA 533
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMA---RSCY 567
Y A+AIDEAVRNAVA G DP+ + +DNFC DP P+ + L ++ R+
Sbjct: 534 YWMMANAIDEAVRNAVAVGGDPDFMSGVDNFCWCDPVQSDKTPDGHYKLAQLVRANRALE 593
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ L + P +SGKDS N+Y + G ++SIPP++L S MG++ D+ R SDFK+ G
Sbjct: 594 HFCLAYGVPCVSGKDSMKNDY-TGGGTKISIPPTVLFSVMGVIDDVNRTVTSDFKRAGER 652
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAA-ELYKKLHSNIMKGLVLSCHDL 686
IYL+G + GS A++ GI A VP AA Y+ L+ I GLV +CHDL
Sbjct: 653 IYLLGLTRREMAGSEAAQVLGI---SCADVPQVDAPAALARYRALYGAIRAGLVTACHDL 709
Query: 687 SEGGLAAALYEMCLSG 702
S+GGLA AL EMCL G
Sbjct: 710 SDGGLAVALAEMCLGG 725
>gi|147921719|ref|YP_684461.1| putative phosphoribosylformylglycinamidine synthase, synthetase
domain [uncultured methanogenic archaeon RC-I]
gi|110619857|emb|CAJ35135.1| putative phosphoribosylformylglycinamidine synthase, synthetase
domain [uncultured methanogenic archaeon RC-I]
Length = 993
Score = 541 bits (1393), Expect = e-152, Method: Composition-based stats.
Identities = 325/802 (40%), Positives = 466/802 (58%), Gaps = 76/802 (9%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK------------RPCTDAEFETIAQTW 48
++D+EL+A+S + AL + EM+AIR+++K + RP TD E ET+AQTW
Sbjct: 186 VSDDELIAISRKGTLALTLEEMKAIRDYFKQPEVLAERRNLGLGPRP-TDVELETLAQTW 244
Query: 49 SEHCVHKTFKAKID-IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI--DAPWVLSSF 105
SEHC HK F A ID ++ TE + S+ K+ I+K+T++I + W++S F
Sbjct: 245 SEHCKHKIFNATIDYVENGKHTE----------IKSLFKSCIRKSTEEISKEKGWLVSVF 294
Query: 106 VDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDV 163
DNAGII+F + Y V+FK ETHN PSA++P+GGA TG+ G RD G A+ A TDV
Sbjct: 295 KDNAGIIKFTDDYNVAFKVETHNSPSALDPYGGAITGIVGCDRDSAGTGKGAKLIAHTDV 354
Query: 164 LCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVY 223
LCF P +P HP+RI+ GV+ G+KD GNK G+PT+NG + + + Y PLVY
Sbjct: 355 LCFASPYYKGR-LPPRIFHPRRIMEGVVRGIKDGGNKCGVPTINGAILFDDRYGGKPLVY 413
Query: 224 CGCAGIAPRGKHRTKPS------AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
CG G+ P +PS G I+ GG+ G+DG+ GATFSS + + +
Sbjct: 414 CGSLGLMP-ATINGEPSEDKYVKPGTFIVMAGGRIGKDGIHGATFSSEELHEGS---PAT 469
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-ALGCDVDLAKIPV 336
+VQIG+PI QKK+ ++L++ARDQGLY+ ITD GAGG SS+VGE A + GC++ L K P+
Sbjct: 470 AVQIGDPITQKKMLDMLLEARDQGLYTCITDNGAGGLSSSVGETAQFSGGCEIYLEKAPL 529
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ LSEAQERM +AVP +KL+A L VE T +G++T V +
Sbjct: 530 KYHGLDPWEILLSEAQERMTLAVPPEKLDAFMSLAKRRGVEATVVGKYTDTGKFHVFYDG 589
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKY-PEYKEPDLNAALKAVINHHAVNSKE 455
+ + ++ FLH G P+ +L+A + KP + PE L L+ +++ + SKE
Sbjct: 590 RTVASIDMDFLHDGLPEMRLQA----EWKPVQRTEPELPTEGLTMYLQDLMSDLNIASKE 645
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
++R YDHEVQGG+V++P G + + P DA VI+P+ + +A+SN +NP G +D Y
Sbjct: 646 WVIRQYDHEVQGGSVIKPLTGKDNDGPGDAGVIRPL-LDRMAGIAVSNGINPYYGDIDTY 704
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP-----NRPETMWALIEMAR---SCY 567
A AIDEA+RN +A G + A+LDNFC DP P+ + L ++ R + Y
Sbjct: 705 HMTACAIDEAIRNIIAVGGSLRQIALLDNFCWCDPIYDPEKTPDGKYKLAQLVRANQALY 764
Query: 568 NTALVFKTPFISGKDSFNNEY--LSSEGK--RVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
+ F TP ISGKDS N+Y +GK ++SIPP++L SA+G+VPD+ + D K
Sbjct: 765 DYTTAFGTPCISGKDSMKNDYKLKGEDGKEYKISIPPTVLFSAVGVVPDVRKCVTMDAKM 824
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFG-----IPSGESAAVPPFKKEAAELYKKLHSNIMKG 678
G +Y VG + GGS F L G +P ++A A ++Y + I G
Sbjct: 825 AGDLVYAVGMTKDELGGSRFYNLLGHTGNNVPKVDAAM-------AKKIYDAMSGAIDAG 877
Query: 679 LVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKI----ASLFGETTGCLLVE 734
LV SCHD S+GGLA AL E SG G ++ D + R+ A ++ LF E+ +V
Sbjct: 878 LVASCHDCSDGGLAVALAETAFSG-GFGMEIDLN-RVPAERLFRDAQVLFSESASRFVVT 935
Query: 735 IKEENRSAFEKEMEGASIYEIG 756
+ + AFE+ MEG IG
Sbjct: 936 VAPDKAKAFEQAMEGVPCALIG 957
>gi|78358231|ref|YP_389680.1| Phosphoribosylformylglycinamidine synthase [Desulfovibrio
desulfuricans G20]
gi|78220636|gb|ABB39985.1| Phosphoribosylformylglycinamidine synthase [Desulfovibrio
desulfuricans G20]
Length = 993
Score = 537 bits (1383), Expect = e-150, Method: Composition-based stats.
Identities = 331/805 (41%), Positives = 460/805 (57%), Gaps = 61/805 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKT-------EK-----RPCTDAEFETIAQTW 48
M+D + A S + AL + EM IR+ Y EK RP TDAE E +AQTW
Sbjct: 186 MDDAAMAAFSRDNTLALSLEEMHCIRDHYAQPDVKAAREKMGLPARP-TDAEVEALAQTW 244
Query: 49 SEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLS 103
SEHC HK F A+I ++ G +NS+ KT I+ +T + + LS
Sbjct: 245 SEHCKHKIFSARIRY-------RNEETGTGETINSLYKTCIQGSTSLLRKRMGKKDFCLS 297
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVT 161
F DNAG+I F + + V K ETHN PSA++P+GGA TG+ GV RD MG + A T
Sbjct: 298 VFKDNAGVISFTDTHSVCIKVETHNSPSALDPYGGALTGIVGVNRDPMGTGMGANMVCNT 357
Query: 162 DVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPL 221
DV CF P E +P LHP+R++ GV EGV+ GNK G+PTVNG + +H+ Y PL
Sbjct: 358 DVFCFASP-FYEEKLPPRLLHPRRVLEGVREGVEHGGNKSGVPTVNGSIVFHDRYLGKPL 416
Query: 222 VYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
VYCG G+ P R H K GD ++ GG+ G+DG+ GATFSS + +
Sbjct: 417 VYCGTVGMIPATVAGRPGHEKKALPGDIVVMAGGRIGKDGIHGATFSSEELHEGS---PA 473
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIP 335
++VQIG+PI Q+K + ++ ARD+GLY+AITD GAGG SS+VGEMA G C +D+++ P
Sbjct: 474 TAVQIGDPITQRKTYDFIMRARDKGLYNAITDNGAGGLSSSVGEMAEDTGGCRIDVSRAP 533
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+KY GL PWE+ LSEAQERM +AVP K+E L DVE T LG FT V +G
Sbjct: 534 LKYDGLRPWEILLSEAQERMTLAVPPAKIEEFLALAREMDVEATALGEFTDSGYFHVTYG 593
Query: 396 EKEIINLSCGFLHSGPPQRKLKAA--PPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNS 453
EK + LS FLH G PQ +L A P+ P I + + L LK ++ + S
Sbjct: 594 EKPVAYLSMEFLHDGVPQMQLDAVWERPQLPAPAIDVDDAHQSSL---LKTMLGRLNICS 650
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
KE ++R YDHEV+GG+V++P G + P DA V++P+ E + + +S+ + P+ +D
Sbjct: 651 KEYVIRQYDHEVKGGSVVKPLVGVLRDGPADAGVMRPL-LENEAGIVLSHGICPKFSDID 709
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMARSCYNT 569
Y A+AIDEAVRNAVA G + + A +DNFC DP P+ + L ++ R+ N
Sbjct: 710 TYWMMANAIDEAVRNAVAVGGNIDHMAGVDNFCWCDPVQSEKTPDGRYKLAQLVRA--NK 767
Query: 570 AL-----VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKE 624
AL + P ISGKDS N+Y + G ++SIPP++L S +G++PD+ + SDFK+
Sbjct: 768 ALAHFCQAYGVPCISGKDSMKNDY-TGGGTKISIPPTVLFSVLGVIPDVNKTVTSDFKQA 826
Query: 625 GSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSC 683
G IYL+G + GGS A+ GI SA VP A L Y+ L+ I GLV C
Sbjct: 827 GDGIYLLGVTRRELGGSELADELGI---LSADVPHVDAVPALLRYRTLYKAIGAGLVSGC 883
Query: 684 HDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGA-SKIASLFGETTGCLLVEIKEENRS 741
HDLS+GGLA A+ EM L+G GA++ + G+ +K L+ E+ LLV + ++
Sbjct: 884 HDLSDGGLAVAVAEMALAGRTGADVNLNAVALAGSLNKAEVLYSESASRLLVTVPAAQQN 943
Query: 742 AFEKEMEGASIYEIGKTCGKAGLKL 766
AFE+ +G IG+ L++
Sbjct: 944 AFEQMFKGQHCTRIGQVTAHDSLRV 968
>gi|82548296|gb|ABB82986.1| phosphoribosylformylglycinamidine synthase II [uncultured organism
HF10_3D09]
Length = 1008
Score = 535 bits (1377), Expect = e-150, Method: Composition-based stats.
Identities = 320/796 (40%), Positives = 460/796 (57%), Gaps = 61/796 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKR------------PCTDAEFETIAQTW 48
++DEEL+ LSN+ AL++ EM+ IR Y+ E TD E E +AQTW
Sbjct: 194 LSDEELIQLSNDGLLALNLNEMQTIRNHYRNENTRDIRTSVGISPDAPTDVELECLAQTW 253
Query: 49 SEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI--DAPWVLSSFV 106
SEHC HK F +KI T E+ ++SI KT+I K T D+ + W+LS F
Sbjct: 254 SEHCKHKIFASKIHHIDTETNEDT-------VIDSIFKTHIMKPTHDMAKEVDWLLSVFH 306
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVL 164
DN+G+I +++ + + KAETHN PSA++P+GGA TG+ GV RD++G + ARP A TDV
Sbjct: 307 DNSGVIAWNDDWSICMKAETHNSPSALDPYGGAMTGIVGVNRDILGTGLGARPIANTDVF 366
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
CFG PD + +P HP R++ GV GV+ GN+ GIPT+NG + + E Y PLVYC
Sbjct: 367 CFGPPDWEGD-LPSTLFHPSRVLRGVHAGVRVGGNESGIPTINGSIVFDERYIGKPLVYC 425
Query: 225 GCAGIAPR------GKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
G G+ PR H P+ GD + +GG+ G DG+ GATFSS+ + T + S+
Sbjct: 426 GTVGLMPRRLADGRESHEKNPTPGDLVYMVGGRVGSDGIHGATFSSLEL---TDESPSSA 482
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVDLAKIPVK 337
VQIG+PI QKK+ ++L++ARD L + TD GAGG SS++GEMA GC++DL K+P+K
Sbjct: 483 VQIGDPITQKKMMDMLLEARDSCLITCTTDNGAGGLSSSIGEMAEYTNGCEIDLGKVPLK 542
Query: 338 YQGLAPWELWLSEAQERMVIAV-PNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+GL+ WE+ +SE+QERM +AV P DK A + L + ++VE T + FT V+ G+
Sbjct: 543 QEGLSSWEILVSESQERMTVAVAPKDK-SAFEALAELHEVEATQVATFTNTGYFHVKHGD 601
Query: 397 KEIINLSCGFLHSGPPQRKLKA--APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSK 454
+ + L FLH G PQ +L++ PP+ + + + D N L ++ + SK
Sbjct: 602 ETVAYLPIEFLHDGVPQLELESEWVPPQH----VTFVPPSDLDHNVLLNEMLARPNIASK 657
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E VR YDHEV TV++P+ G E + P DA +I P+ + + +S + PR +D
Sbjct: 658 ETWVRQYDHEVIAQTVVKPFVGVERDGPGDAGLIAPIHGN-PQGLVVSCGIAPRYSDIDA 716
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMARSCYNTA 570
A A++IDEAVRNAV G D +K A LDNFC DP P+ + L ++ R+
Sbjct: 717 GAMVAASIDEAVRNAVCVGVDIDKMAGLDNFCWPDPIESEKTPDGKFKLAQLVRANRELE 776
Query: 571 LV---FKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
V ++ P +SGKDS N+Y ++SIPP++L S G PD+ + S+FK+ G
Sbjct: 777 RVCRAYRLPCVSGKDSMKNDY-GVWPNKISIPPTMLFSLFGNQPDVRKTATSNFKRHGER 835
Query: 628 IYLVGKPQFSFGGSVFAELF---GIPSGESAAVPPFKK--EAAELYKKLHSNIMKGLVLS 682
IYLVG G S A G +G VP + E+Y+KL S+I GL+ +
Sbjct: 836 IYLVGTTYEELGASEVAFHLRERGDATGIGGQVPRLEDPVRQLEVYRKLSSSIQNGLIRT 895
Query: 683 CHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIAS-LFGETTGCLLVEIKEENR 740
HD SEGGLA AL EMC+ G GA + D +G+ + S L+ E+ G ++V ++ E+
Sbjct: 896 AHDCSEGGLAVALAEMCIGGRCGAIIDID---GIGSCDVFSRLWSESLGRIIVSVEAEHE 952
Query: 741 SAFEKEMEGASIYEIG 756
AF + MEGA I+ IG
Sbjct: 953 LAFVEMMEGADIHLIG 968
>gi|118743819|ref|ZP_01591820.1| phosphoribosylformylglycinamidine synthase II [Geobacter lovleyi
SZ]
gi|118683331|gb|EAV89729.1| phosphoribosylformylglycinamidine synthase II [Geobacter lovleyi
SZ]
Length = 996
Score = 533 bits (1373), Expect = e-149, Method: Composition-based stats.
Identities = 322/796 (40%), Positives = 445/796 (55%), Gaps = 60/796 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK------------RPCTDAEFETIAQTW 48
++DEELL +S + AL + EM+ I+ Y+ + +P TD E E +AQTW
Sbjct: 186 VSDEELLRISKDGVLALTLEEMKIIQTHYRDPQVLAERSKQGLGSKP-TDVELECLAQTW 244
Query: 49 SEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLS 103
SEHC HK F + + + +++ + S+ K+YI++ T ++ D + LS
Sbjct: 245 SEHCKHKIFAGTVQYEDENGNKQE--------IKSLFKSYIQRVTKEVRQNMGDKDFCLS 296
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVT 161
F DNAG+I FDE + FK ETHN PSA++P+GGA TG+ GV RD G ++ T
Sbjct: 297 VFKDNAGVITFDENNSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGQGSKLIFNT 356
Query: 162 DVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
DV CF P D P +P LHP+RI GV+EGV+ GNK GIPTVNG + + E +A
Sbjct: 357 DVFCFADPFYDKP---LPARLLHPRRIFEGVVEGVEHGGNKSGIPTVNGSIVFDERFAGK 413
Query: 220 PLVYCGCAGIAPR-----GKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLV+CG AG+ P H GD I+ GG+ G+DG+ GATFSS ++ ++
Sbjct: 414 PLVFCGTAGMMPARVNGIPGHEKSIKPGDLIVMAGGRIGKDGIHGATFSSEELNENSPVT 473
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVDLAK 333
A VQIG+PI QK++ + LI ARD+GLY ITD GAGG SS++GEMA GC +DLAK
Sbjct: 474 A---VQIGDPITQKRMFDFLIRARDKGLYRFITDNGAGGLSSSIGEMAGECNGCRMDLAK 530
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
P+KY GL PWE+ +SEAQERM +AVP +KL+ + VE T LG FT ++
Sbjct: 531 APLKYPGLNPWEILISEAQERMSMAVPPEKLDEFMAMSKRFGVESTVLGEFTDSGTFHIQ 590
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNS 453
+GE + L F+H G P ++ A P + P + D A L ++ + S
Sbjct: 591 YGEATVAWLPMEFMHEGLPPMQIPAKWQPPVTP--EAPAQHKEDWTADLLGLLGQLNICS 648
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
KE +VR YDHEVQGG+V++P+ G + P DAAV++P+ + K V +S+ + PR +D
Sbjct: 649 KESVVRRYDHEVQGGSVVKPFTGVTNDGPSDAAVVRPI-LDSYKGVVVSHGICPRYSDID 707
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD-------PNRPETMWALIEMARSC 566
Y AA+AIDEA+RN VA G +PE A LDNFC D P+ P M L+ ++
Sbjct: 708 AYHMAANAIDEALRNYVAVGGNPEHWAGLDNFCWCDPVLSEKTPDGPYKMAQLVRANQAL 767
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
+ + P ISGKDS N++ K +SIPP+LL S +G +PDI DFK+ G
Sbjct: 768 LDYCVPLNLPLISGKDSMKNDFYDGSTK-ISIPPTLLFSVIGTIPDIRNAVTMDFKRPGD 826
Query: 627 AIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDL 686
I L+G + GGS + + G + V A YK LH IM GLV SCHDL
Sbjct: 827 IICLLGATKDELGGSEYLAMQGYTGNKVPKVD--LASALARYKALHQAIMNGLVASCHDL 884
Query: 687 SEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIAS----LFGETTGCLLVEIKEENRS 741
S+GGLA AL E S G G ++ G + + LF E+ LLV + S
Sbjct: 885 SDGGLAVALAESSFSGGFGCRVELGNVHFEGDQRYRTDEVLLFSESASRLLVTVHPAQWS 944
Query: 742 AFEKEMEGASIYEIGK 757
AFE+ M G + +IG+
Sbjct: 945 AFEEAMAGTTFSQIGQ 960
>gi|85858204|ref|YP_460406.1| phosphoribosylformylglycinamidine synthase [Syntrophus
aciditrophicus SB]
gi|85721295|gb|ABC76238.1| phosphoribosylformylglycinamidine synthase [Syntrophus
aciditrophicus SB]
Length = 993
Score = 532 bits (1370), Expect = e-149, Method: Composition-based stats.
Identities = 325/792 (41%), Positives = 448/792 (56%), Gaps = 57/792 (7%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEK-----------RPCTDAEFETIAQTWSE 50
+D L +S R AL + EMR IR +++ E TD E E +AQTWSE
Sbjct: 187 DDAALQEISGSRVLALTVEEMRIIRNYFQDEAVQRRRREAGIGEGITDVELECLAQTWSE 246
Query: 51 HCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP-----WVLSSF 105
HC HK F SL + + ++S+ K+ +K +T+ I W LS F
Sbjct: 247 HCKHKIF--------NSLITYEDEHGNSRVIDSLFKSCVKGSTNAIREELGPEDWCLSVF 298
Query: 106 VDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDV 163
VDNAGII+F+++Y + FK ETHN PSA++P+GGA TG+ GV RD G A+ TDV
Sbjct: 299 VDNAGIIKFNDEYNLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGAGKGAKLIFNTDV 358
Query: 164 LCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPL 221
CF P D P +P LHP+RI GV EGV+ GNK GIPTVNG + + E + PL
Sbjct: 359 FCFASPFYDQP---LPPRILHPRRIYEGVREGVEHGGNKSGIPTVNGCLVFDERFLGKPL 415
Query: 222 VYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
VYCG GI P H + GD ++ GG+ G+DG+ GATFSS + + A
Sbjct: 416 VYCGTGGIMPARILGEPSHIKEVQPGDIVVMTGGRIGKDGIHGATFSSEELHEGSPVTA- 474
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-ALGCDVDLAKIP 335
VQIG+PI QK++ + L+ ARDQGLY AITD GAGG SS+VGEMAS + GC++DL K P
Sbjct: 475 --VQIGDPITQKRMTDFLLLARDQGLYRAITDNGAGGLSSSVGEMASLSGGCEIDLKKAP 532
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+KY GL PWE+ +SEAQERM +AV DK++A L VE T LGRFT + V +G
Sbjct: 533 LKYAGLHPWEILISEAQERMTLAVYPDKIDAFLNLAAKMGVEATVLGRFTDSGMFHVCYG 592
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINHHAVNSK 454
E+ + L FLH G PQ KL A + P P++ EP DL ALK ++ + SK
Sbjct: 593 EQTVAFLDMEFLHEGLPQMKLNA---RWTPPAFPEPDFPEPADLGRALKEMLGRLNICSK 649
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E +VR YDHEVQGG+ ++P G + P DAAV++P+ E + + +++ + PR +D
Sbjct: 650 ESVVRQYDHEVQGGSAVKPLVGAADDGPGDAAVLRPI-LESFEGIVVASGICPRYSDIDT 708
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMAR---SCY 567
YA AA AIDEA+RNAVA GA + A LDNFC DP P+ + L ++ R + Y
Sbjct: 709 YAMAACAIDEAIRNAVAVGASLRRMAGLDNFCWCDPVESEKTPDGRYKLAQLVRANEALY 768
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ ++ P ISGKDS N+Y+ G ++SIPP+LL S + + D+ R D K+ G
Sbjct: 769 DYTRIYGVPCISGKDSMKNDYMIG-GTKISIPPTLLFSVIARMDDVRRAVTMDAKQPGDL 827
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLS 687
+Y++G+ + GGS + L G V ++A Y+ L + GLV SCHD S
Sbjct: 828 VYVLGETRKELGGSEWYALNGFVGNSVPRVD--ARKARSRYEALCGAMEAGLVASCHDCS 885
Query: 688 EGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIAS-LFGETTGCLLVEIKEENRSAFEK 745
+GGL AL E+ + G+G + G ++ LF E+ L+V + +R AFE
Sbjct: 886 DGGLGVALAEIAFAGGLGMAVDVSLAPSAGITRNDDLLFSESQSRLVVTVSPADREAFES 945
Query: 746 EMEGASIYEIGK 757
M + + IG+
Sbjct: 946 MMADSEMACIGR 957
>gi|78223148|ref|YP_384895.1| Phosphoribosylformylglycinamidine synthase II [Geobacter
metallireducens GS-15]
gi|78194403|gb|ABB32170.1| Phosphoribosylformylglycinamidine synthase II [Geobacter
metallireducens GS-15]
Length = 996
Score = 531 bits (1367), Expect = e-148, Method: Composition-based stats.
Identities = 320/807 (39%), Positives = 456/807 (56%), Gaps = 64/807 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK------------RPCTDAEFETIAQTW 48
++D+ELL +S + AL + EM+ I+ Y+ K RP TD E E +AQTW
Sbjct: 186 VSDDELLRISKDGVLALTLEEMKIIQAHYRDPKVQEERRKQGLGVRP-TDVELECLAQTW 244
Query: 49 SEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLS 103
SEHC HK F + + ++ + S+ K++I++ T D+ D+ + LS
Sbjct: 245 SEHCKHKIFAGTVHYEDEQGNRQE--------IKSLFKSFIQRTTKDVREKLGDSDFCLS 296
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVT 161
F DNAG+I F++ + + FK ETHN PSA++P+GGA TG+ GV RD G A+ T
Sbjct: 297 VFKDNAGVIRFNDDWSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGKGAKLIFNT 356
Query: 162 DVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
DV CF P D P +P LHP+RI GV+EGV+ GNK GIPTVNG + + E +A
Sbjct: 357 DVFCFADPFYDKP---LPSRLLHPRRIYEGVVEGVEHGGNKSGIPTVNGSLVFDERFAGK 413
Query: 220 PLVYCGCAGIAPRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLV+CG AGI P H GD I+ GG+ G+DG+ GATFSS ++ ++
Sbjct: 414 PLVFCGTAGIMPATLNGELGHEKAIKPGDLIVMTGGRIGKDGIHGATFSSEELNENSPVT 473
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAK 333
A VQIG+PI QK++ + LI ARD+GLY ITD GAGG SS++GEM+ G C +DL K
Sbjct: 474 A---VQIGDPITQKRMFDFLIRARDKGLYRFITDNGAGGLSSSIGEMSGECGGCRMDLEK 530
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
P+KY GL PWE+ +SEAQERM +AVP ++++ + +VE T LG FT +
Sbjct: 531 APLKYPGLDPWEILISEAQERMSLAVPPEQIDEFLAMAKRFNVEATVLGEFTDSGYFHIL 590
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKA--APPKDGKPFIKYPEYKEPDLNAALKAVINHHAV 451
+G++ + L F+H G P +L A PP+ +P ++ + D A LKA++ +
Sbjct: 591 YGDRTVAWLPMEFMHEGLPPMQLPAKWVPPRHAEPTLQV----KGDYTADLKALLGSLNI 646
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE +VR YDHEVQGG+V++P+ G + P DAAV++P+ + + V +++ + PR
Sbjct: 647 CSKESVVRRYDHEVQGGSVVKPFTGVANDGPSDAAVVRPI-LDSFEGVVVAHGICPRYSD 705
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPE-------TMWALIEMAR 564
+D Y A+AIDEA+RN VA G + A LDNFC DP R E M L+ +
Sbjct: 706 IDTYHMTANAIDEALRNYVAVGGALDLVAGLDNFCWCDPVRSEKTPDGEYKMAQLVRANQ 765
Query: 565 SCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKE 624
+ Y+ L + P ISGKDS N++ K +SIPP++L S +G + D R D K+
Sbjct: 766 ALYDVCLAYNLPLISGKDSMKNDFYDGATK-ISIPPTILFSVIGKIEDARRSVTMDAKRP 824
Query: 625 GSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCH 684
G +YL+G+ GGS + L G+ V P ++A + Y LH+ I GLV SCH
Sbjct: 825 GDVVYLLGRTGNELGGSEYLALQGVIGNNVPTVNP--EKALKRYNALHTAITGGLVASCH 882
Query: 685 DLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASK--IASLFGETTGCLLVEIKEEN 739
DLS+GGLA AL E + GI A+L + T A + A LF E+ LV ++ N
Sbjct: 883 DLSDGGLAVALAEKAFAGGYGISADLGKVLWTGDDAMRNDAALLFSESASRHLVTVRPGN 942
Query: 740 RSAFEKEMEGASIYEIGKTCGKAGLKL 766
R AFE M G IG + +++
Sbjct: 943 RDAFEAIMAGNCFSAIGVVTEEGAVRI 969
>gi|77918932|ref|YP_356747.1| phosphoribosylformylglycinamidine(FGAM) synthase, glutamine
amidotransferase domain [Pelobacter carbinolicus DSM
2380]
gi|77545015|gb|ABA88577.1| phosphoribosylformylglycinamidine(FGAM) synthase, glutamine
amidotransferase domain [Pelobacter carbinolicus DSM
2380]
Length = 1020
Score = 523 bits (1348), Expect = e-146, Method: Composition-based stats.
Identities = 316/796 (39%), Positives = 449/796 (56%), Gaps = 65/796 (8%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPC-----------TDAEFETIAQTWS 49
++DEEL+ +S E AL++ EM+ I+ F + TD E E +AQTWS
Sbjct: 213 VSDEELMRISREGVLALNLEEMKEIQAFANDPQNQAERQKMGLSTRLTDVELEALAQTWS 272
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP-----WVLSS 104
EHC HK F A+ID + + E ++S+ KT+I AT D+ A + LS
Sbjct: 273 EHCKHKIFSARIDYEDSEGNSET--------IDSLFKTFIVGATRDVRAAKGQKDFCLSV 324
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DNAG+I F++ + + FK ETHN PSA++P+GGA TG+ GV RD G + AR TD
Sbjct: 325 FKDNAGVIRFNDDWSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGMGARLIFNTD 384
Query: 163 VLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLV 222
V CF P +E +P LHP+RI GV+EGV+ GNK G+PTVNG + + + +A PLV
Sbjct: 385 VFCFASP-FYSEPLPPRLLHPRRIFEGVVEGVEHGGNKSGVPTVNGSIVFDDRFAGKPLV 443
Query: 223 YCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
YCG A + P + H + GD I+ +GG+ G+DG+ GATFSS + + +
Sbjct: 444 YCGTAALMPAEIHGQPGHVKQAQVGDRIMMVGGRIGKDGIHGATFSSEELHEGS---PAT 500
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIPV 336
+VQIG+PI QK++ + LI ARD+GLY++ITD GAGG SS+VGEMA G ++ L + P+
Sbjct: 501 AVQIGDPITQKRMFDFLIIARDRGLYNSITDNGAGGLSSSVGEMAEDTGGFEMHLDRAPL 560
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ +SEAQERM +AVP DK EA L DVE T+LG F +
Sbjct: 561 KYSGLQPWEILISEAQERMTVAVPIDKAEAFIALAKEMDVEATDLGVFNDSGYYHCLYDG 620
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINHHAVNSKE 455
K + L FLH+G PQ +LKA + PE+ +P D A L+ ++ + SKE
Sbjct: 621 KTVTYLPMEFLHAGVPQLQLKARWENRA---YQEPEFSQPVDAEATLRHLLARLNICSKE 677
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
+VR YDHEVQ GTVL+P G + P DAA+++P+ + + V +++ + PR +D Y
Sbjct: 678 SVVRRYDHEVQAGTVLKPLVGIANDGPADAAMVRPL-PDSFEGVVVAHGITPRYSDIDTY 736
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM-------WALIEMARSCYN 568
A A+DE +RN VA G + + A LDNFC DP + E L+ ++ Y+
Sbjct: 737 HMMACAVDEGLRNYVAVGGNIDHVAGLDNFCWCDPVQSEKTPDGEYKAAQLVRANKALYD 796
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
L F P ISGKDS N+Y + K +SIPP++L S +G V DI + D K+ G I
Sbjct: 797 YCLAFGVPLISGKDSMKNDYQIGDTK-ISIPPTVLFSVIGKVDDIRKGVTMDAKRPGDLI 855
Query: 629 YLVGKPQFSFGGSVFAELFG-----IPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSC 683
YL+G + G S + ++ G +P ++A A + Y+ ++ +GL+ SC
Sbjct: 856 YLLGITRNELGASEYYDMLGHLGKNVPKVDAAT-------ALQRYRTVNQAQKQGLLASC 908
Query: 684 HDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKI---ASLFGETTGCLLVEIKEENR 740
HDLS+GGL AL E +G G + D + A LF ET LLV +K +N+
Sbjct: 909 HDLSDGGLGIALAETAFAG-GFGMHVDLRNVKCDEVLREDAVLFSETASRLLVTVKPDNK 967
Query: 741 SAFEKEMEGASIYEIG 756
+AFEK G + +G
Sbjct: 968 TAFEKLFNGQDVSMLG 983
>gi|145620681|ref|ZP_01776703.1| Phosphoribosylformylglycinamidine synthase [Geobacter bemidjiensis
Bem]
gi|144942994|gb|EDJ78097.1| Phosphoribosylformylglycinamidine synthase [Geobacter bemidjiensis
Bem]
Length = 996
Score = 517 bits (1331), Expect = e-144, Method: Composition-based stats.
Identities = 322/795 (40%), Positives = 448/795 (56%), Gaps = 60/795 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK-----------RPCTDAEFETIAQTWS 49
++DEEL+ +S + AL + EM+ I+ Y+ K TD E E +AQTWS
Sbjct: 186 VSDEELMRISRDGVLALTLDEMKIIQAHYRDAKVLEARKSVGLGAAPTDVELEALAQTWS 245
Query: 50 EHCVHKTFKAKIDI-DGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP-----WVLS 103
EHC HK F A + DG EE + S+ K++I+K T D+ A + LS
Sbjct: 246 EHCKHKIFSADVSYEDGEGNREE---------IKSLFKSFIQKTTADVRAALGEKDYCLS 296
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVT 161
F DNAG+I F++ + + FK ETHN PSA++P+GGA TG+ GV RD G A+ T
Sbjct: 297 VFKDNAGVIRFNDDWSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGKGAKLIFNT 356
Query: 162 DVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPL 221
DV CF P E +PK LHP+RI GV+EGV+ GNK GIPTVNG + + + +A PL
Sbjct: 357 DVFCFADPFYGKE-LPKRLLHPRRIYEGVVEGVEHGGNKSGIPTVNGSLVFDDRFAGKPL 415
Query: 222 VYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
V+CG AGI P H+ + GD I+ GG+ G+DG+ GATFSS ++ ++
Sbjct: 416 VFCGTAGIMPAKIKDEPSHQKRIVPGDLIVMTGGRIGKDGIHGATFSSEELNENS---PV 472
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIP 335
S+VQIG+PI QK++ + LI ARD+GLY ITD GAGG SS++GEM+ G C +DL+ P
Sbjct: 473 SAVQIGDPITQKRMFDFLIRARDKGLYRFITDNGAGGLSSSIGEMSEECGGCQLDLSLAP 532
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+KY GLAPWE+ +SEAQERM +AVP + ++A ++ +VE T LG FT + + +G
Sbjct: 533 LKYPGLAPWEILISEAQERMSLAVPPENIDAFMEMAKRFNVEATVLGSFTDSGIFHMLYG 592
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-PDLNAALKAVINHHAVNSK 454
EK + L F+H+G P ++ P + KP + P E D LKA+++ + SK
Sbjct: 593 EKTVAYLPLSFMHAGLPPMQI---PARWAKPVHEEPAVAEAADYTGDLKALLSSLNICSK 649
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E +VR YDHEVQGG+V++P+ G + + P DAAV++P+ + +AV + + + PR +D
Sbjct: 650 ESVVRRYDHEVQGGSVVKPFTGVDNDGPSDAAVVRPI-LDSFEAVVVGHGICPRYSDIDA 708
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD-------PNRPETMWALIEMARSCY 567
Y AA+AIDE +RN VA G + A LDNFC D P+ P M L+ ++ Y
Sbjct: 709 YDMAANAIDEGLRNYVAVGGSLDLLAGLDNFCWCDPVLSDRTPDGPYKMAQLVRANKALY 768
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ VF P ISGKDS N++ K +SIPP+LL S +G + D D K+ G
Sbjct: 769 DYCTVFSMPLISGKDSMKNDFYDGTTK-ISIPPTLLFSVIGKMEDARLAVTMDAKRAGDQ 827
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAA-ELYKKLHSNIMKGLVLSCHDL 686
+YL+G G S + G VP AA Y+ H + GLV SCHDL
Sbjct: 828 VYLLGTTANELGASEYLAQKGYVGNN---VPKVDANAALATYRAYHGALNAGLVASCHDL 884
Query: 687 SEGGL-AAALYEMCLSGIGAEL---KEDFHTRLGASKIAS-LFGETTGCLLVEIKEENRS 741
S+GGL AA G G EL K F K A LF E+ LLV ++ E +
Sbjct: 885 SDGGLAVAAAESAFAGGFGMELDLAKVAFKGDAADKKDAVLLFSESASRLLVTVRPEKAA 944
Query: 742 AFEKEMEGASIYEIG 756
AFEK + G + +IG
Sbjct: 945 AFEKALAGTTFAKIG 959
>gi|39996734|ref|NP_952685.1| phosphoribosylformylglycinamidine synthase II, putative [Geobacter
sulfurreducens PCA]
gi|39983615|gb|AAR35008.1| phosphoribosylformylglycinamidine synthase II, putative [Geobacter
sulfurreducens PCA]
Length = 996
Score = 516 bits (1328), Expect = e-144, Method: Composition-based stats.
Identities = 323/802 (40%), Positives = 443/802 (55%), Gaps = 74/802 (9%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKT------------EKRPCTDAEFETIAQTW 48
++D+EL+ +S E AL + EM+ I+ Y+ +P TDAE E IAQTW
Sbjct: 186 VSDDELMRISREGVLALTLDEMKVIQAHYRNPAVIAERSKVGLAAKP-TDAELEAIAQTW 244
Query: 49 SEHCVHKTFKAKID-IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVL 102
SEHC HK F I+ ID EE + S+ KT+I+ T + + + L
Sbjct: 245 SEHCKHKIFSGTIEYIDENGNREE---------IRSLFKTFIQGTTKTVREQLGERDFCL 295
Query: 103 SSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAV 160
S F DNAG+I +++ + + FK ETHN PSA++P+GGA TG+ GV RD G ++
Sbjct: 296 SVFKDNAGVIRWNDDWSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGKGSKLIFN 355
Query: 161 TDVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
TDV CF P D P +P LHP+RI GV+EGV+ GNK GIPTVNG + + + +A
Sbjct: 356 TDVFCFASPFYDKP---LPSRLLHPRRIYEGVVEGVEHGGNKSGIPTVNGSIVFDDRFAG 412
Query: 219 NPLVYCGCAGIAPRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGD 273
PLV+CG AG+ P H GD I+ GG+ G+DG+ GATFSS + +
Sbjct: 413 KPLVFCGTAGLMPATINGAPAHEKFIRPGDLIVMTGGRIGKDGIHGATFSSEELHEGSPV 472
Query: 274 VAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLA 332
A VQIG+PI QK++ + LI ARD+GLY+ ITD GAGG SS++GEM+ G C +DL+
Sbjct: 473 TA---VQIGDPITQKRMTDFLIRARDKGLYNFITDNGAGGLSSSIGEMSGECGGCRMDLS 529
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
K P+KY GL PWE+ +SEAQERM +AVP + ++ + VE T LG FT +
Sbjct: 530 KAPLKYPGLDPWEILISEAQERMSLAVPPEHIDEFIAMARRFGVEATILGEFTDSGYFHI 589
Query: 393 RFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP------DLNAALKAVI 446
+G++ I L FLH G PP + + ++EP D A LK ++
Sbjct: 590 MYGDRTIAYLPMDFLHGG--------LPPMQMRGVWEVKRHEEPALEVKQDYAADLKQLL 641
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
+ SKE +VR YDHEVQGG+V++P+ G + P DAAVI+P+ + + V +S+ +
Sbjct: 642 GSLNICSKESVVRRYDHEVQGGSVVKPFTGVANDGPSDAAVIRPV-LDSFEGVVVSHGIC 700
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEM 562
PR +D Y A+AIDEA+RN VA G + A LDNFC DP P+ + + ++
Sbjct: 701 PRYSDIDAYHMTANAIDEALRNYVAVGGSLDLVAGLDNFCWCDPVQSDKTPDGEYKMAQL 760
Query: 563 ARS---CYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGS 619
RS Y+ + F P ISGKDS N++ K +SIPP+LL S +G + DI
Sbjct: 761 VRSNKALYDYCVAFGIPLISGKDSMKNDFWDGNVK-ISIPPTLLFSVIGKIDDIRTAVTM 819
Query: 620 DFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGL 679
D K+ G +YL+GK + GGS + L G+ V K A Y+ LH I +GL
Sbjct: 820 DAKRPGDIVYLLGKTGYELGGSEYMALKGLVGNSVPQVNTAK--ALPRYRALHRAISQGL 877
Query: 680 VLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASK--IASLFGETTGCLLVE 734
V SCHDLS+GGLA AL E + GI AEL + A K A LF E+ LV
Sbjct: 878 VASCHDLSDGGLAVALAETAFAGGFGIVAELSRVLWSGDEALKGDAALLFSESASRHLVT 937
Query: 735 IKEENRSAFEKEMEGASIYEIG 756
++ ENR AFE M IG
Sbjct: 938 VRPENREAFESVMAANCFSSIG 959
>gi|110601447|ref|ZP_01389633.1| phosphoribosylformylglycinamidine synthase II [Geobacter sp.
FRC-32]
gi|110547838|gb|EAT61078.1| phosphoribosylformylglycinamidine synthase II [Geobacter sp.
FRC-32]
Length = 995
Score = 508 bits (1307), Expect = e-142, Method: Composition-based stats.
Identities = 315/809 (38%), Positives = 442/809 (54%), Gaps = 69/809 (8%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTE------------KRPCTDAEFETIAQTW 48
+ DEELL +S E AL + EM+ I+ Y+ + RP TD E E +AQTW
Sbjct: 186 VTDEELLRISREGVLALTLDEMKIIQAHYRDDLVLAARRSQGLGDRP-TDVELEALAQTW 244
Query: 49 SEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLS 103
SEHC HK F ++ EQ ++S+ K++I++ T + D + LS
Sbjct: 245 SEHCKHKIFSGNVEYVDEKGNREQ--------ISSLFKSFIQRTTATVRENLGDKDFCLS 296
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVT 161
F DNAG+I F++ Y + FK ETHN PSA++P+GGA TG+ GV RD G AR T
Sbjct: 297 VFKDNAGVIRFNDDYSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGKGARLIFNT 356
Query: 162 DVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
DV CF P D P +P LHP+RI GVIEGV+ GNK GIPTVNG + + + +A
Sbjct: 357 DVFCFASPFYDKP---LPARLLHPRRIYEGVIEGVEHGGNKSGIPTVNGSLVFDDRFAGK 413
Query: 220 PLVYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLV+CG AGI P H + GD I+ GG+ G+DG+ GATFSS ++ S+
Sbjct: 414 PLVFCGTAGIMPAVINGEPSHVKRIDPGDLIVMTGGRIGKDGIHGATFSSEELNESS--- 470
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAK 333
S+VQIG+PI QK++ + L+ ARD+GLY+ ITD GAGG SS++GEM+ G C +DL+K
Sbjct: 471 PVSAVQIGDPITQKRMTDFLLRARDRGLYNFITDNGAGGLSSSIGEMSEECGGCRLDLSK 530
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
P+KY GL PWE+ +SEAQERM +AVP K++ L VE T LG FT +
Sbjct: 531 APLKYAGLDPWEILISEAQERMSLAVPPAKIDEFLALARIMGVEATVLGEFTDSGYFHIL 590
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP----DLNAALKAVINHH 449
GE + L FLH G P +++ G IK+ E +P D L ++
Sbjct: 591 HGETTVAFLPISFLHGGLPPMEMR------GVWEIKHHEEPKPADKSDYTEDLLKLLGSL 644
Query: 450 AVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQ 509
+ SKE +VR YDHEVQGG+V++P+ G + P DAAV++P+ + + V + + + PR
Sbjct: 645 NICSKESVVRRYDHEVQGGSVVKPFTGVNNDGPSDAAVVRPI-LDSFEGVVVGHGICPRY 703
Query: 510 GLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPE-------TMWALIEM 562
+D Y AA+AIDE +RN +A G P A LDNFC DP + E M L+
Sbjct: 704 SDIDAYHMAANAIDEGLRNYIAVGGSPNLVAGLDNFCWCDPVKSEKTPDGEYKMAQLVRA 763
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
++ Y+ + F P ISGKDS N++ K +SIPP+LL S +G + D + D K
Sbjct: 764 NKALYDYCVAFGIPLISGKDSMKNDFYDGTTK-ISIPPTLLFSVIGKMEDARKAVTMDVK 822
Query: 623 KEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAA-ELYKKLHSNIMKGLVL 681
+ G +Y++G+ GGS + G VP E A Y+ H+ +++GLV
Sbjct: 823 RPGDVVYILGETADELGGSEYLAAKGFTGNR---VPQVNAEKALNSYRAYHAAVVEGLVA 879
Query: 682 SCHDLSEGGL-AAALYEMCLSGIGAELKEDFHTRLGASKI---ASLFGETTGCLLVEIKE 737
SCHDLS+GGL AA G G + D ++ + A LF E+ LL+ +
Sbjct: 880 SCHDLSDGGLAVAAAESAFAGGFGLAVNLDAVPIKASASLDDEAILFSESASRLLITVDP 939
Query: 738 ENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
+AFE M G ++ IG+ L +
Sbjct: 940 GKSAAFENVMSGQAVARIGQVTADTTLTI 968
>gi|94263059|ref|ZP_01286878.1| Phosphoribosylformylglycinamidine synthase II [delta
proteobacterium MLMS-1]
gi|93456602|gb|EAT06710.1| Phosphoribosylformylglycinamidine synthase II [delta
proteobacterium MLMS-1]
Length = 1002
Score = 507 bits (1306), Expect = e-142, Method: Composition-based stats.
Identities = 320/813 (39%), Positives = 448/813 (55%), Gaps = 79/813 (9%)
Query: 3 DEELLALSNERRAALDIYEMRAIREFY--------KTEK---RPCTDAEFETIAQTWSEH 51
D+EL+ +S E AL + EM+ IRE + E+ + TD E E +AQ+WSEH
Sbjct: 194 DDELMRISREGVLALTLAEMKLIREHLADPAVIAARQEQGLAQEITDVELEVLAQSWSEH 253
Query: 52 CVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSSFV 106
C HK F +I T+ E +S+ T+I++ T +I D W LS F
Sbjct: 254 CKHKIFNGEIHYQDTTSGEHT-------VFHSLFDTFIRQPTAEIRRRLGDNDWCLSVFK 306
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVL 164
DNAG+I F++ + ++FK ETHN PSA++P+GGA TG+ GV RD G + A+ A TDV
Sbjct: 307 DNAGVIRFNQDWNLAFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGMGAKLIANTDVF 366
Query: 165 CFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLV 222
CF P D P +P LHPKRI GV GV+ GNK GIPTVNG + + +A PLV
Sbjct: 367 CFASPFYDQP---LPARLLHPKRIFEGVRLGVEHGGNKSGIPTVNGSIVFDSRFAGKPLV 423
Query: 223 YCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
+CG GI P R K + GD I+ GG+ G+DG+ GATFSS + + +
Sbjct: 424 FCGTVGIMPALVGGRPSQDKKANPGDLIVMTGGRIGKDGIHGATFSSEELHEGS---PAT 480
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-ALGCDVDLAKIPV 336
+VQIG+P QKK+ + L+ ARD+GLY+ ITD GAGG SS+VGEMA + G + L + P+
Sbjct: 481 AVQIGDPFTQKKMFDCLLKARDRGLYTCITDNGAGGLSSSVGEMAEDSGGFQLHLERAPL 540
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ +SEAQERM +AVP K++ LC +VE T LG FT V +
Sbjct: 541 KYPGLQPWEIMISEAQERMTLAVPPAKIDEFLALCAKMEVEATVLGEFTDSGNFHVLYQG 600
Query: 397 KEIINLSCGFLHSGPPQRKLKA--APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSK 454
+ + L F+H G P ++ A PP +P ++PE +PDL A L A++ + SK
Sbjct: 601 RTVACLGMDFIHKGLPPLQMTARWEPPTHAEP--QWPE--QPDLGAELHALLGRLNICSK 656
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E +VR YDHEVQGG+V++P G + + P DAAV++P+ + + + +++ + P+ +D
Sbjct: 657 EYVVRQYDHEVQGGSVVKPLTGVDNDGPSDAAVLRPL-LDSFEGLVLAHGICPKYSEIDT 715
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD-------PNRPETMWALIEMARSCY 567
Y AA+AIDEA+RNAVA GAD E A LDNFC D P+ P + L+ ++
Sbjct: 716 YHMAANAIDEAIRNAVAVGADLEHMAGLDNFCWCDPVLSEKTPDGPYKLAQLVRANQALA 775
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ AL F P ISGKDS N+Y+ + K +SIPP+LL S + + D+ R D KK G
Sbjct: 776 DCALAFGVPCISGKDSMKNDYMIDDVK-ISIPPTLLFSVVAKIADVRRAVTMDAKKSGDL 834
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSCHDL 686
+YL+G + GGS +A G VP + A Y+ L I GLV S HDL
Sbjct: 835 VYLLGITRPELGGSEYAARHQGEGGIGNQVPQVEPATALFRYRALQQAIAAGLVASAHDL 894
Query: 687 SEGGL-------------AAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLV 733
S+GGL L ++ G E ++DF LF E+ LLV
Sbjct: 895 SDGGLAVAAAESAFAGGLGLDLDLGLVACEGIE-RDDF----------LLFSESPSRLLV 943
Query: 734 EIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
+ + FE+ M GA+ +G + L+L
Sbjct: 944 TVAPADADEFEQLMAGAAASRLGVVTSEPVLRL 976
>gi|94269831|ref|ZP_01291575.1| Phosphoribosylformylglycinamidine synthase II [delta
proteobacterium MLMS-1]
gi|93451056|gb|EAT02010.1| Phosphoribosylformylglycinamidine synthase II [delta
proteobacterium MLMS-1]
Length = 1002
Score = 506 bits (1302), Expect = e-141, Method: Composition-based stats.
Identities = 319/815 (39%), Positives = 447/815 (54%), Gaps = 83/815 (10%)
Query: 3 DEELLALSNERRAALDIYEMRAIREFY--------KTEK---RPCTDAEFETIAQTWSEH 51
D+EL+ +S E AL + EM+ IRE + E+ TD E E +AQ+WSEH
Sbjct: 194 DDELMRISREGVLALTLAEMKLIREHLADPAVIAARQEQGLAEEITDVELEVLAQSWSEH 253
Query: 52 CVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSSFV 106
C HK F +I T+ E +S+ T+I++ T +I D W LS F
Sbjct: 254 CKHKIFNGEIHYQDTTSGEHT-------VFHSLFDTFIRQPTAEIRRRLGDNDWCLSVFK 306
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVL 164
DNAG+I F++++ ++FK ETHN PSA++P+GGA TG+ GV RD G + A+ A TDV
Sbjct: 307 DNAGVIRFNQEWNLAFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGMGAKLIANTDVF 366
Query: 165 CFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLV 222
CF P D P +P LHPKRI GV GV+ GNK GIPTVNG + + +A PLV
Sbjct: 367 CFASPFYDQP---LPARLLHPKRIFEGVRLGVEHGGNKSGIPTVNGSIVFDSRFAGKPLV 423
Query: 223 YCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
+CG GI P R K + GD I+ GG+ G+DG+ GATFSS + + +
Sbjct: 424 FCGTVGIMPALVGGRPSQDKKANPGDLIVMTGGRIGKDGIHGATFSSEELHEGS---PAT 480
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-ALGCDVDLAKIPV 336
+VQIG+P QKK+ + L+ ARD+GLY+ ITD GAGG SS+VGEMA + G + L + P+
Sbjct: 481 AVQIGDPFTQKKMFDCLLKARDRGLYTCITDNGAGGLSSSVGEMAEDSGGFQLHLERAPL 540
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
KY GL PWE+ +SEAQERM +AVP K++ LC +VE T LG FT V +
Sbjct: 541 KYPGLQPWEIMISEAQERMTLAVPPAKIDEFLALCAKMEVEATVLGEFTDSGNFHVLYQG 600
Query: 397 KEIINLSCGFLHSGPPQRKLKA--APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSK 454
+ + L F+H G P ++ A PP +P ++PE +PDL A L A++ + SK
Sbjct: 601 RTVACLGMDFIHKGLPPLQMTARWEPPTHAEP--QWPE--QPDLGAELHALLGRLNICSK 656
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E +VR YDHEVQGG+V++P G + + P DAAV++P+ + + + +++ + P+ +D
Sbjct: 657 EYVVRQYDHEVQGGSVVKPLTGVDNDGPSDAAVLRPL-LDSFEGLVLAHGICPKYSEIDT 715
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD-------PNRPETMWALIEMARSCY 567
Y AA+AIDEA+RNAVA GAD E A LDNFC D P+ P + L+ ++
Sbjct: 716 YHMAANAIDEAIRNAVAVGADLEHMAGLDNFCWCDPVLSEKTPDGPYKLAQLVRANQALA 775
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ AL F P ISGKDS N+Y+ + K +SIPP+LL S + + D+ + D KK G
Sbjct: 776 DCALAFGVPCISGKDSMKNDYMIDDVK-ISIPPTLLFSVVAKIADVRQAVTMDAKKSGDL 834
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSCHDL 686
+YL+G + GGS +A G VP + A Y+ L I GLV S HDL
Sbjct: 835 VYLLGITRPELGGSEYAARHQGEGGIGNQVPQVEPATALFRYRALQQAIAAGLVASAHDL 894
Query: 687 SEGGL---------------AAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCL 731
S+GGL L + GI ++DF LF E+ L
Sbjct: 895 SDGGLAVAAAESAFAGGLGLDLDLGLVACEGID---RDDF----------LLFSESPSRL 941
Query: 732 LVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
LV + + FE+ M GA+ +G + L+L
Sbjct: 942 LVTVAPADADEFEQLMAGAAASRLGVVTSEPVLRL 976
>gi|95930094|ref|ZP_01312833.1| Phosphoribosylformylglycinamidine synthase [Desulfuromonas
acetoxidans DSM 684]
gi|95133788|gb|EAT15448.1| Phosphoribosylformylglycinamidine synthase [Desulfuromonas
acetoxidans DSM 684]
Length = 993
Score = 498 bits (1281), Expect = e-139, Method: Composition-based stats.
Identities = 316/803 (39%), Positives = 445/803 (55%), Gaps = 59/803 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFY---KTEKRPC--------TDAEFETIAQTWS 49
++D+EL+ +S + AL++ EM+ I+ F + +K+ TDAE E +AQTWS
Sbjct: 186 VSDDELMQISRDGMLALNLEEMKTIQAFIADAEVQKQRAAAGVPAQLTDAELEALAQTWS 245
Query: 50 EHCVHKTFKAKIDID-GTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLS 103
EHC HK F A+I D G TE +NS+ KTYI AT DI D + LS
Sbjct: 246 EHCKHKIFSAEISYDDGEGNTET---------INSLFKTYIMGATRDIRAAKGDKDFCLS 296
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVT 161
F DNAG+IEF +++ + +K ETHN PSA++P+GGA TG+ GV RD G AR T
Sbjct: 297 VFKDNAGVIEFTDEWSMVYKVETHNSPSALDPYGGALTGIVGVNRDPFGTGRGARLIFNT 356
Query: 162 DVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
DV CF P D P +P LHP+RI GV+EGV+ GNK GIPTVNG + + + +A
Sbjct: 357 DVFCFASPFYDQP---LPPRLLHPRRIFEGVVEGVEHGGNKSGIPTVNGSLVFDDRFAGK 413
Query: 220 PLVYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLVYCG A + P R H K GDHI+ +GG+ G+DG+ GATFSS ++ D
Sbjct: 414 PLVYCGSAALMPTELHGRPGHEKKAEVGDHILMVGGRVGKDGIHGATFSSEELNE---DS 470
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAK 333
++VQIG+PI Q+++ + LI ARD+GLY+AITD GAGG SS+VGEMA G ++ L +
Sbjct: 471 PVTAVQIGDPITQRRMFDFLIIARDKGLYTAITDNGAGGLSSSVGEMAEDTGGFEMHLDR 530
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
P+KY GL PWE+ +SEAQERM +AVP +K++ L DVE T+LG FT
Sbjct: 531 CPLKYAGLQPWEILISEAQERMTLAVPPEKVDEFITLAKEMDVEATDLGLFTDSGYYHCL 590
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNS 453
+ + L FLH G PQ K+ A + K + P + AL+ +++ V S
Sbjct: 591 YQGETATYLPMSFLHEGAPQMKIPAK--WEVKQHAEPTAADLPAADEALETLLSSLNVCS 648
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
KE +VR YDHEVQG TV +P G + + P D +V++P+ + ++ ++ + PR +D
Sbjct: 649 KECVVRRYDHEVQGATVQKPLTGVDNDGPADGSVVRPL-FDSFAGISTAHGICPRYSDID 707
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPE-------TMWALIEMARSC 566
Y A AIDEA+RN V+ G + + A LDNFC DP + E L+ ++
Sbjct: 708 TYHMMACAIDEALRNYVSVGGNIDHVAGLDNFCWCDPVKSERTPDGEYKAAQLVRANKAL 767
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
Y L F P ISGKDS N+Y + K +SIPP++L S +G V D+ + D K+ G
Sbjct: 768 YEYCLAFGVPLISGKDSMKNDYQIGDTK-ISIPPTVLFSVIGKVDDVRQTVSMDVKRPGD 826
Query: 627 AIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSCHD 685
+YL+G + G S EL+ +VP + A L Y+ L+ GL+ SCHD
Sbjct: 827 KVYLLGMTKAELGAS---ELYTQLGFVGNSVPTVDAKTALLRYRTLNRAQQAGLIASCHD 883
Query: 686 LSEGGLAAALYEMCLSGIGAELKEDFHTRLGA--SKIASLFGETTGCLLVEIKEENRSAF 743
LS+GGL A E +G + R S + L+ E+ LLV + + F
Sbjct: 884 LSDGGLGVAAAEAAFAGGFGVDIDLSQVRCDGTLSDVEILYSESQSRLLVTVAPDKAEEF 943
Query: 744 EKEMEGASIYEIGKTCGKAGLKL 766
EK G + +G+ + LK+
Sbjct: 944 EKLFAGQEVSVLGEVTEQPRLKV 966
>gi|148264123|ref|YP_001230829.1| phosphoribosylformylglycinamidine synthase II [Geobacter
uraniumreducens Rf4]
gi|146397623|gb|ABQ26256.1| phosphoribosylformylglycinamidine synthase II [Geobacter
uraniumreducens Rf4]
Length = 996
Score = 498 bits (1281), Expect = e-139, Method: Composition-based stats.
Identities = 313/799 (39%), Positives = 435/799 (54%), Gaps = 68/799 (8%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK------------RPCTDAEFETIAQTW 48
+ D+ELL +S + AL + EM I+ Y+ E +P TD E E +AQTW
Sbjct: 186 VGDDELLRISRDGVLALTLDEMLIIQAHYRDENVVAMRRTLGLGGQP-TDVELEALAQTW 244
Query: 49 SEHCVHKTFKAKID-IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVL 102
SEHC HK F ++ +D +E+ + S+ KT+I+ T + D + L
Sbjct: 245 SEHCKHKIFSGNVEYVDELGNSEK---------ITSLFKTFIQNTTAKVRENLGDKDYCL 295
Query: 103 SSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAV 160
S F DNAG+I+F++ + FK ETHN PSA++P+GGA TG+ GV RD G AR
Sbjct: 296 SVFKDNAGVIKFNDDSSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGKGARLIFN 355
Query: 161 TDVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
TDV CF P D P +P LHP+RI GV+EGV+ GNK GIPTVNG + + + +A
Sbjct: 356 TDVFCFASPFYDKP---LPSRLLHPRRIYEGVVEGVEHGGNKSGIPTVNGSLVFDDRFAG 412
Query: 219 NPLVYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGD 273
PLV+CG AGI P H K GD I+ GG+ G+DG+ GATFSS ++ S+
Sbjct: 413 KPLVFCGTAGIMPAVINGEPSHLKKIYPGDLIVMTGGRIGKDGIHGATFSSEELNESS-- 470
Query: 274 VAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLA 332
S+VQIG+PI QK++ + LI ARD+ LY+ ITD GAGG SS++GEM+ G C +DLA
Sbjct: 471 -PVSAVQIGDPITQKRMTDFLIRARDRDLYNFITDNGAGGLSSSIGEMSEECGGCRMDLA 529
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
K P+KY GL PWE+ +SEAQERM +AVP KL+ L VE + LG FT +
Sbjct: 530 KAPLKYPGLDPWEILISEAQERMSLAVPPAKLDEFLALARRMGVEASVLGEFTDSGYFHI 589
Query: 393 RFGEKEIINLSCGFLHSGPPQRKLKAA--PPKDGKPFIKYPEYKEPDLNAALKAVINHHA 450
+G+K + L FLH G P +++ K+ +P + D L +++
Sbjct: 590 LYGDKTVAYLPLSFLHGGLPPMEMRGVWETKKNEEP----EASNKSDYTEELVKLLSSLN 645
Query: 451 VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQG 510
+ SKE +VR YDHEVQGG+V++P+ G + + P D+AV++P+ + + V + + + PR
Sbjct: 646 ICSKESVVRRYDHEVQGGSVVKPFTGVDNDGPSDSAVVRPI-LDSFEGVVVGHGICPRYS 704
Query: 511 LLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPE-------TMWALIEMA 563
+D Y AA+AIDE +RN VA G + A LDNFC DP + E M L+
Sbjct: 705 DIDTYHMAANAIDEGLRNYVAVGGSLDLVAGLDNFCWCDPVKSEKTPDGEYKMAQLVRAN 764
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
++ Y+ + F P ISGKDS N++ K +SIPP+LL S +G + D + D K+
Sbjct: 765 KALYDYCVAFGIPLISGKDSMKNDFYDGSTK-ISIPPTLLFSVIGKIEDANKAVTMDVKR 823
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAA-ELYKKLHSNIMKGLVLS 682
G +YL+G+ GGS E + VP E A Y+ H +MKGLV S
Sbjct: 824 PGDVVYLLGETANELGGS---EYYAAKGYLGNRVPQVDAEQALSRYRAYHQAVMKGLVAS 880
Query: 683 CHDLSEGGL-AAALYEMCLSGIGAELKEDFHTRLGASKIAS----LFGETTGCLLVEIKE 737
CHDLS+GGL AA G G + GA + LF E+ LLV +
Sbjct: 881 CHDLSDGGLAVAAAESAFAGGFGISIDLGAVPFKGADNERTDEVILFSESASRLLVTVHP 940
Query: 738 ENRSAFEKEMEGASIYEIG 756
+ AFE M G IG
Sbjct: 941 DKTDAFEAAMSGQLFARIG 959
>gi|118579579|ref|YP_900829.1| phosphoribosylformylglycinamidine synthase II [Pelobacter
propionicus DSM 2379]
gi|118502289|gb|ABK98771.1| phosphoribosylformylglycinamidine synthase II [Pelobacter
propionicus DSM 2379]
Length = 996
Score = 494 bits (1273), Expect = e-138, Method: Composition-based stats.
Identities = 311/803 (38%), Positives = 445/803 (55%), Gaps = 76/803 (9%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK------------RPCTDAEFETIAQTW 48
++D+EL+ +S E AL + EM+ I+ Y+ K +P TD E E +AQTW
Sbjct: 186 VSDDELMRISKEGILALTLDEMKIIQAHYRDAKVLEERKKVGLGPKP-TDVELECLAQTW 244
Query: 49 SEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLS 103
SEHC HK F + + + +++ + S+ K++I++ T D+ + + LS
Sbjct: 245 SEHCKHKIFAGTVQYEDENGNKQE--------IRSLFKSFIQRTTKDVREKMGEKDFCLS 296
Query: 104 SFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVT 161
F DNAG+I+F++ + + FK ETHN PSA++P+GGA TG+ GV RD G A+ T
Sbjct: 297 VFKDNAGVIKFNDDHSLVFKVETHNSPSALDPYGGALTGIVGVNRDPFGTGKGAKLIFNT 356
Query: 162 DVLCFGHP--DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
DV CF P + P +P LHP+RI GV+EGV+ GNK GIPTVNG + + E YA
Sbjct: 357 DVFCFADPFFEKP---LPSRLLHPRRIYEGVVEGVEHGGNKSGIPTVNGSLVFDERYAGK 413
Query: 220 PLVYCGCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLV+CG AGI P H GD I+ GG+ G+DG+ GATFSS ++ ++
Sbjct: 414 PLVFCGTAGIMPARLNGEPSHEKSIKPGDVIVMTGGRIGKDGIHGATFSSEELNENSPVT 473
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAK 333
A VQIG+PI QK++ + LI ARD+GLY ITD GAGG SS++GEMA G C +DL+
Sbjct: 474 A---VQIGDPITQKRMFDFLIRARDKGLYRFITDNGAGGLSSSIGEMAGECGGCRMDLSC 530
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
P+KY GLAPWE+ +SEAQERM +AVP + L+ + VE T LG FT V +
Sbjct: 531 APLKYPGLAPWEILISEAQERMSLAVPPETLDEFLSMAKRFGVEATVLGEFTDSGVFHML 590
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKA--APPKDGKPFIKYPEYKEPDL------NAALKAV 445
+GE+ + L F+H G P +L A PPK Y+EP+L +A L+A+
Sbjct: 591 YGERTVAWLPMEFMHEGLPPLQLPAKWTPPK----------YEEPELVAGGEYSADLRAL 640
Query: 446 INHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNAL 505
++ + SKE +VR YDHEVQGG+V++P+ G + P DAA+++P+ + + V ++ +
Sbjct: 641 LSSLNICSKESVVRRYDHEVQGGSVVKPFTGVTNDGPSDAAIVRPI-LDSFEGVVTAHGI 699
Query: 506 NPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD-------PNRPETMWA 558
PR +D Y A+A+DEA+RN VA G E A LDNFC D P+ P M
Sbjct: 700 CPRYSDIDAYHMTANAVDEALRNYVAVGGSLELVAGLDNFCWCDPVLSDKTPDGPYKMAQ 759
Query: 559 LIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPG 618
L+ ++ Y+ + + P ISGKDS N++ K +SIPP+LL S +G + D +
Sbjct: 760 LVRANQALYDICMEYNLPLISGKDSMKNDFYDGSTK-ISIPPTLLFSVIGKIEDARKAVT 818
Query: 619 SDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKG 678
D K+ +YL+G GGS + L G + V A Y+ +
Sbjct: 819 MDVKRPADIVYLLGTTADELGGSEYLALKGKIGNKVPVVDAV--SAYGRYQAYQRAVAAA 876
Query: 679 LVLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASK--IASLFGETTGCLLV 733
+V SCHDLS+GGLA A E + GI +L GA++ + LF E+ LLV
Sbjct: 877 IVASCHDLSDGGLAVAAAESAFAGGFGISLDLSAVPWKGDGAARNDLNLLFSESASRLLV 936
Query: 734 EIKEENRSAFEKEMEGASIYEIG 756
+ E R+ FE M G+ IG
Sbjct: 937 TVHPEKRAEFEAIMAGSCFAPIG 959
>gi|150403102|ref|YP_001330396.1| Phosphoribosylformylglycinamidine synthase [Methanococcus
maripaludis C7]
gi|150034132|gb|ABR66245.1| Phosphoribosylformylglycinamidine synthase [Methanococcus
maripaludis C7]
Length = 989
Score = 493 bits (1269), Expect = e-137, Method: Composition-based stats.
Identities = 303/800 (37%), Positives = 452/800 (56%), Gaps = 68/800 (8%)
Query: 1 MNDEELLAL---------SNERRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWS 49
++D+EL+ + + ERR ALD+ + AI+E+Y+ E R TD E E +AQTWS
Sbjct: 189 VSDDELIEIGKKGILDPETGERRGPLALDLDYITAIKEYYQKEGRNPTDIELEALAQTWS 248
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC H F ++ID EE I K YI+ AT +I + + +S
Sbjct: 249 EHCKHTIFASQIDD-----IEE-----------GIFKKYIRNATYEIRKELGEKDFCISV 292
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DN+G I FD+++ V+ KAETHN PSA++PFGGA TG+ GV RD +G + A P A
Sbjct: 293 FSDNSGGIIFDDEWMVTDKAETHNSPSALDPFGGAITGIVGVNRDTVGFGLGALPVANKY 352
Query: 163 VLCFGHPDTP-----AENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
C G P+ +N +L P+RI+ G++ GV GN+ GIPT NG V++ + Y
Sbjct: 353 GFCVGRPEDTEIIYRGQNKTNPSLLPRRILDGIVHGVNVGGNQSGIPTPNGFVYFDDTYK 412
Query: 218 SNPLVYCGCAGIAPRG------KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
PLV+ G G+ PR H GD+++ +GG+ G+DG+ GATFSS MD +
Sbjct: 413 GKPLVFVGTIGLIPRKLPDGRLSHEKAAENGDNVVVIGGRVGKDGIHGATFSSEAMDEGS 472
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALG-CDV 329
++VQIG+PI QKK+++ ++ +ARD+GLY++ITD GAGG S +V EMA G V
Sbjct: 473 ---PATAVQIGDPITQKKLSDAVVKEARDKGLYNSITDNGAGGISCSVAEMAEECGGFVV 529
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L K+P+KY GL PWE+W+SE+QER+ ++VP+DKLE L VE +G+F
Sbjct: 530 ELEKVPLKYPGLEPWEIWISESQERVTLSVPDDKLEEFMDLMKIRGVEAVVIGKFNNTDR 589
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPF-IKYPEYKEPDLNAALKAVINH 448
V + K I++L+ FLH+G P+RKL P P+ PE + + V+ +
Sbjct: 590 AVVNYNGKTIMDLNMDFLHNGLPKRKLITKP----YPYKTDEPEIAVENQLKTFETVLGN 645
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
H S E I + YDHEVQ +V++P G +G V A+V++P+ + KK + +S +L PR
Sbjct: 646 HNNCSFEYISKQYDHEVQNNSVIKPLQG-KGRVNGTASVVRPLLSS-KKGLVMSQSLFPR 703
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
+ Y AA A+D A+RN VA G + + AI+DNFC + PE ++ L + A+SCY+
Sbjct: 704 LSEISCYDMAACAMDTAIRNCVAVGGNIDHIAIMDNFCWCSSDEPERLYQLKDAAKSCYD 763
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGSDFKKE 624
A + TP ISGKDS N++ + ++S+ P+L++SA+G++ ++ D K +
Sbjct: 764 YAKTYLTPLISGKDSMFNDFKGFDENNNPIKISVHPTLMMSALGVIDNVENTNSMDLKLK 823
Query: 625 GSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCH 684
IY++G+ + GGS F F G+S V K A +LYKK++ G++ SC
Sbjct: 824 DDLIYVIGETKDECGGSEFYHAFNEVGGKSPKVD--AKSARKLYKKMYELSQNGILSSCA 881
Query: 685 DLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRS 741
++ GGL L +M +S GI A+L + + L KI ++ ET +V I EN
Sbjct: 882 SVAAGGLVITLAKMAISGMLGIEADLSKTPNENLEFEKI--MYSETQSRFIVTIAPENEK 939
Query: 742 AFEKEMEGASIYEIGKTCGK 761
FE M+ I +IGK K
Sbjct: 940 EFENLMKEFKIGKIGKVTEK 959
>gi|42524400|ref|NP_969780.1| phosphoribosylformylglycinamidine synthase II [Bdellovibrio
bacteriovorus HD100]
gi|39576609|emb|CAE80773.1| phosphoribosylformylglycinamidine synthase II [Bdellovibrio
bacteriovorus HD100]
Length = 1009
Score = 492 bits (1266), Expect = e-137, Method: Composition-based stats.
Identities = 313/785 (39%), Positives = 441/785 (56%), Gaps = 59/785 (7%)
Query: 1 MNDEELLALSNERRAALDIY----EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKT 56
+N+E LALS+E + + E+ A R Y + T+ E E +AQTWSEHC HK
Sbjct: 196 INNERGLALSDEEIQTILTHFSSPEVAAERASYGWHGK-ITEVELECLAQTWSEHCKHKI 254
Query: 57 FKAKIDIDGTSLTEEQKKAYPGLC---VNSIIKTYIKKATDDID-APWVLSSFVDNAGII 112
F A++D E +P L + S+ K+YI+KAT D+D +++S F DNAGI+
Sbjct: 255 FAAEVDY------TEACGDFPALGDKKITSLYKSYIQKATKDLDDCGYLVSVFKDNAGIV 308
Query: 113 EFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVM--GVSARPFAVTDVLCFGHPD 170
+FD K V K ETHN PSA++PFGGA TG+ GV RD++ G+ A+P A TDV C P+
Sbjct: 309 DFDSKLNVCVKVETHNSPSALDPFGGALTGILGVNRDILGCGLGAKPVANTDVFCLSTPN 368
Query: 171 T-PAENVPKGT---LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
PA + P+ P I GV +GV++ GN+ GIPT+NG + +A+ PL++ G
Sbjct: 369 LFPASDSPQRPELLKDPGVIFRGVHQGVEEGGNQSGIPTINGAFCFASEFAAKPLIFVGS 428
Query: 227 AGIAPRGKH-RTKPSA----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQI 281
G+ P+ H R S GD I+ GG+ G+DG+ GATFSS+ + +VA + VQI
Sbjct: 429 VGVMPKTVHGRASESKEIRPGDLIVVAGGRLGKDGVHGATFSSLALH---DNVASNVVQI 485
Query: 282 GEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-ALGCDVDLAKIPVKYQG 340
G+ I QK++ + + ARD G AITD GAGG SS++GEMA + G +DL PVKY G
Sbjct: 486 GDSITQKRLLDFTLKARDNGWIQAITDNGAGGVSSSIGEMAQYSGGARMDLGLHPVKYSG 545
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
L WE+ +SE+QERM AV + L L VE LG FT + G++ +
Sbjct: 546 LEYWEMLVSESQERMSYAVSPNHLMDFMNLARHMGVEAFVLGEFTDSGSFDIFHGKEPLA 605
Query: 401 NLSCGFLHSGPPQRKLKAA--PPKDGKPFIKYPEYKEP----DLNAALKAVINHHAVNSK 454
L FLH G + KLKA PK + + + E K P DL AALK V+ + V S+
Sbjct: 606 KLKLEFLHEGLSRMKLKAHFDGPKQYQEYFR-AEGKAPLTGNDLAAALKKVLANPNVASR 664
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEG---KKAVAISNALNPRQGL 511
E +VR YDHEVQG T ++PY G + DA V+ + G AVA+SN L P+
Sbjct: 665 EPLVRYYDHEVQGATRVKPYGGKTQSGANDAGVLD-LSVHGGDDNNAVAVSNGLCPQFSW 723
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMARSC- 566
D Y A A+DE+VRN VA GADP K A++DNFC DP + P+ + ++ R+C
Sbjct: 724 YDTYLMAQKAVDESVRNLVATGADPAKMALVDNFCWPDPTPKASNPDAAHKMAQLVRACA 783
Query: 567 --YNTALVFKTPFISGKDSFNNEYLSS----EGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
Y+ AL ++ PF+SGKDS N+++ + ++S+PP+LL++AM VPD +
Sbjct: 784 GLYDAALAYRAPFVSGKDSMKNDFIGKTKGGDTVKISVPPTLLVTAMAQVPDATKTAPGF 843
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV 680
F+ G IYL+G P S SV ++ F +P ESA P +LY ++ + K L+
Sbjct: 844 FQNAGDLIYLLGTPTQSLYASVLSQEFTVP--ESAPEYPNLARNKDLYFRIFTAHQKTLL 901
Query: 681 LSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENR 740
SCHD+SEGGL AL E SG G L + L + L+ ET +V +K ++
Sbjct: 902 QSCHDISEGGLMTALAE---SGFGNNLGMKLN--LESFTWNELWSETGSLFVVSVKPADK 956
Query: 741 SAFEK 745
S FE+
Sbjct: 957 SQFEE 961
>gi|134046522|ref|YP_001098007.1| Phosphoribosylformylglycinamidine synthase [Methanococcus
maripaludis C5]
gi|132664147|gb|ABO35793.1| Phosphoribosylformylglycinamidine synthase [Methanococcus
maripaludis C5]
Length = 989
Score = 489 bits (1258), Expect = e-136, Method: Composition-based stats.
Identities = 302/805 (37%), Positives = 457/805 (56%), Gaps = 78/805 (9%)
Query: 1 MNDEELLAL---------SNERRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWS 49
++D+EL+ + + ERR ALD+ + AI+++Y+ E R TD E E +AQTWS
Sbjct: 189 VSDDELIEIGKKGILDPETGERRGPLALDLDYITAIKKYYQKEGRNPTDIELEALAQTWS 248
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC H F ++ID EE I K YI+ AT++I + + +S
Sbjct: 249 EHCKHTIFASQIDD-----IEE-----------GIFKKYIRNATNEIREELGEKDFCISV 292
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DN+G I FD+++ V+ KAETHN PSA++PFGGA TG+ GV RD +G + A P A
Sbjct: 293 FSDNSGGIIFDDEWMVTDKAETHNSPSALDPFGGAITGIVGVNRDTVGFGLGALPVANKY 352
Query: 163 VLCFGHPDTP-----AENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
C G P+ +N +L P+RI+ G++ GV GN+ GIPT NG V++ + Y
Sbjct: 353 GFCVGRPEDTKIIYRGQNKSNPSLLPRRILDGIVHGVNVGGNQSGIPTPNGFVYFDDTYK 412
Query: 218 SNPLVYCGCAGIAPRG------KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
PLV+ G G+ PR H GD+I+ +GG+ G+DG+ GATFSS MD +
Sbjct: 413 GKPLVFVGTIGLIPRKLPDGRLSHEKAAENGDNIVIIGGRVGKDGIHGATFSSEAMDEGS 472
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALG-CDV 329
++VQIG+PI QKK+++ +I +ARD+ LY++ITD GAGG S +V EMA G V
Sbjct: 473 ---PATAVQIGDPITQKKLSDAVIKEARDRELYNSITDNGAGGISCSVAEMAEECGGFVV 529
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L ++P+KY GL PWE+W+SE+QER+ ++V +DKLE L VE +G+F
Sbjct: 530 ELEEVPLKYPGLEPWEIWISESQERVTLSVSDDKLEEFMDLMKIRGVEAVVIGKFNNTDR 589
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYP-EYKEPDLNA-----ALK 443
V + K I++L+ FLH+G P+RKL P YP + +EP++ +
Sbjct: 590 AVVNYNGKTIMDLNMDFLHNGLPKRKLITKP---------YPYKTEEPEITVKNQLKTFE 640
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN 503
++ +H S E I + YDHEVQ +V++P G +G V A+VI+P+ + +K + +S
Sbjct: 641 KILGNHNNCSFEYISKQYDHEVQNNSVIKPLQG-KGRVNGAASVIRPLLSS-QKGLVMSQ 698
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
+L PR + Y AA A+D A+RN VA G + AI+DNFC + PE ++ L + A
Sbjct: 699 SLFPRLSEISCYDMAACALDTAIRNCVAVGGNINHIAIMDNFCWCSSDEPERLYQLKDAA 758
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGS 619
+SCY+ A ++ TP ISGKDS N++ + ++S+ P+L++SA+G++ ++ +
Sbjct: 759 KSCYDYAKIYLTPLISGKDSMFNDFKGFDENNNQIKISVHPTLMMSALGVIDNVEKTNSM 818
Query: 620 DFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGL 679
D K + IY++G+ + GGS F FG G+S V K A +LY+K++ KG+
Sbjct: 819 DLKLKDDLIYVIGETKDECGGSEFYHAFGEVGGKSPKVD--AKSARKLYEKMYELSQKGI 876
Query: 680 VLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIK 736
SC ++ GGLA L +M +S G+ A+L + + L KI ++ ET +V I
Sbjct: 877 FSSCASVAAGGLAITLAKMAISGMLGLEADLSKAPNENLDFGKI--MYSETQSRFIVTIA 934
Query: 737 EENRSAFEKEMEGASIYEIGKTCGK 761
EN FE M+ I +IGK K
Sbjct: 935 PENEKEFENLMKEFKIGKIGKVTEK 959
>gi|45357742|ref|NP_987299.1| Phosphoribosylformylglycinamidine synthase II [Methanococcus
maripaludis S2]
gi|45047302|emb|CAF29735.1| Phosphoribosylformylglycinamidine synthase II [Methanococcus
maripaludis S2]
Length = 989
Score = 487 bits (1254), Expect = e-135, Method: Composition-based stats.
Identities = 302/802 (37%), Positives = 451/802 (56%), Gaps = 72/802 (8%)
Query: 1 MNDEELLAL---------SNERRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWS 49
++D+EL+ + + ERR ALD+ + AI+E+Y+ E R TD E E +AQTWS
Sbjct: 189 VSDDELIEIGKKGILDPETGERRGPLALDLDYITAIKEYYQKEGRNPTDIELEALAQTWS 248
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC H F ++ID EE I K YI+ AT++I + + +S
Sbjct: 249 EHCKHTIFASQIDD-----IEE-----------GIFKKYIRNATNEIREELGEKDFCISV 292
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DN+G I FD+++ V+ KAETHN PSA++PFGGA TG+ GV RD +G + A P A
Sbjct: 293 FSDNSGGIIFDDEWMVTDKAETHNSPSALDPFGGAITGIVGVNRDTVGFGLGALPVANKY 352
Query: 163 VLCFGHPDTP-----AENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
C G P+ +N +L P+RI+ G++ GV GN+ GIPT NG V++ + Y
Sbjct: 353 GFCVGRPEDTEIIYRGQNKTNPSLLPRRILDGIVHGVNVGGNQSGIPTPNGFVYFDDTYK 412
Query: 218 SNPLVYCGCAGIAPRG------KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
PLV+ G G+ PR H GD+I+ +GG+ G+DG+ GATFSS MD +
Sbjct: 413 GKPLVFVGTIGLIPRKLPDGRLSHEKAAENGDNIVIIGGRVGKDGIHGATFSSEAMDEGS 472
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALG-CDV 329
++VQIG+PI QKK+++ +I +ARD+GLY++ITD GAGG S +V EMA G V
Sbjct: 473 ---PAAAVQIGDPITQKKLSDAVIKEARDKGLYNSITDNGAGGISCSVAEMAEECGGFVV 529
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L ++P+KY GL PWE+W+SE+QER+ ++VP+DKLE L VE +G+F
Sbjct: 530 ELEEVPLKYPGLEPWEIWISESQERVTLSVPDDKLEEFMDLMKIRGVEAVVIGKFNNTDR 589
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPF---IKYPEYKEPDLNAALKAVI 446
V + K I++L FLH+G P+RKL KP+ + PE + + ++
Sbjct: 590 AVVNYNGKTIMDLEMDFLHNGLPKRKLIT------KPYSYRTEEPEITVENQLETFEKIL 643
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
+H S E I + YDHEVQ +V++P G +G V A+VI+P+ + +K + +S +L
Sbjct: 644 GNHNNCSFEYISKQYDHEVQNNSVIKPLQG-KGRVNGTASVIRPLLSS-QKGLVMSQSLL 701
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSC 566
PR + Y AA A+D A+RN VA G + AI+DNFC + PE ++ L + A+SC
Sbjct: 702 PRLSEISCYDMAACAMDTAIRNCVAVGGNINHIAIMDNFCWCSSDEPERLYQLKDAAKSC 761
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGSDFK 622
Y+ A + TP ISGKDS N++ + ++S+ P+L++SA+G++ +I D K
Sbjct: 762 YDYAKTYLTPLISGKDSMFNDFKGFDENNNPIKISVHPTLMMSALGVIDNIEHTNSMDLK 821
Query: 623 KEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLS 682
+ IY++G+ + GGS F FG G S V K A +LY+K++ KG+ S
Sbjct: 822 LKDDLIYVIGETKDECGGSEFYHAFGEVGGISPKVD--AKSARKLYEKMYELSQKGIFSS 879
Query: 683 CHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
C ++ GGL L +M +S G+ A+L + + + KI ++ ET +V I EN
Sbjct: 880 CASVAAGGLVITLAKMAISGCLGLEADLSKAPNENISFEKI--MYSETQSRFIVTIAPEN 937
Query: 740 RSAFEKEMEGASIYEIGKTCGK 761
FE M+ I +IG K
Sbjct: 938 EKEFENLMKEFKIGKIGNVTEK 959
>gi|150385148|ref|ZP_01923799.1| Phosphoribosylformylglycinamidine synthase [Victivallis vadensis
ATCC BAA-548]
gi|150258469|gb|EDM95741.1| Phosphoribosylformylglycinamidine synthase [Victivallis vadensis
ATCC BAA-548]
Length = 989
Score = 485 bits (1249), Expect = e-135, Method: Composition-based stats.
Identities = 306/800 (38%), Positives = 442/800 (55%), Gaps = 59/800 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEK--------RPCTDAEFETIAQTWSEHC 52
++DE L+ LS + AL + EM+AI+ +++ K R TD E E +AQTWSEHC
Sbjct: 190 VSDEGLMELSRKGTLALSLDEMKAIQNYFRNAKNRESYGLGRNPTDVELEVLAQTWSEHC 249
Query: 53 VHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI--DAPWVLSSFVDNAG 110
HK F AKID + E+++ + S KT+I+K+T +I + W++S F DNAG
Sbjct: 250 KHKIFSAKIDYENLETGEKEE-------IVSCYKTFIQKSTKEIAKEVDWLVSVFKDNAG 302
Query: 111 IIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDV--LCFGH 168
+I+F++K ++ +K ETHN PSA++P+GGA TG+ GV RD +G + +V C G
Sbjct: 303 VIDFNDKLDLVYKVETHNSPSALDPYGGAMTGIVGVNRDPLGTGQGADLLINVWGYCLGS 362
Query: 169 PDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAG 228
P T +VP+G LHP+R+ GV +GV D GN+ GIP NG ++ Y PLVYCG G
Sbjct: 363 PFTKEADVPEGLLHPRRLRDGVHKGVIDGGNQSGIPYGNGWEYFDPRYIGKPLVYCGTVG 422
Query: 229 IAPRGKHRTKPSA-----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGE 283
P+ H ++ GD I+ GG+ G+DG+ GATFSS + D +VQIG+
Sbjct: 423 TLPKTVHGVPGASKTIEPGDLIVMGGGRIGKDGIHGATFSSEELHK---DSPVQAVQIGD 479
Query: 284 PIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVDLAKIPVKYQGLA 342
PI QKK+ + + +ARD+GLY ITD GAGG SS+VGEMA GC +DLA PVKY GL
Sbjct: 480 PITQKKLGDFIREARDRGLYRFITDNGAGGLSSSVGEMAELCNGCRMDLALAPVKYAGLQ 539
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
PWE+ +SEAQERM AVP +K+E + L DVE++ LG FT D +++ K + L
Sbjct: 540 PWEILVSEAQERMSFAVPPEKIEEFKALAKERDVEVSVLGEFTDDGKFHMQYNGKTVACL 599
Query: 403 SCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLN-----AALKAVINHHAVNSKEDI 457
F+H G P+ L A K P++ EPDL+ A L ++ + S E
Sbjct: 600 DIEFMHDGLPRMALTAK--------WKAPKFDEPDLSKRDVAADLAKMMGRLNICSDEYK 651
Query: 458 VRLYDHEVQGGTVLRPYDGPEGNVPQDAAV--IKPMETEGKKAVAISNALNPRQGLLDPY 515
R YDHEV+G +V++P+ G +V DA V I+P+ EG V +S A+ PR +D Y
Sbjct: 652 ARQYDHEVKGLSVIKPFVGKCRDVASDATVTMIEPLSKEG---VILSAAILPRYSDIDTY 708
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMAR---SCYN 568
AAS +D VR +A G +K A LDNFC DP P+ + L ++ R + Y+
Sbjct: 709 HMAASCLDLGVRRVIAVGGKLDKVAGLDNFCWPDPVQSEKTPDGEYKLAQLVRANQALYD 768
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
F+ P ISGKDS N+ + G+++SIPPSLL SA+ + D+ + D K+ G +
Sbjct: 769 YTKKFRVPLISGKDSMKNDS-TRGGRKISIPPSLLFSAIAKMDDVTKSVSLDAKQAGDLV 827
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKE-AAELYKKLHSNIMKGLVLSCHDLS 687
Y++G + GGS E + + VP E A Y + LV S +
Sbjct: 828 YVIGVTKPELGGS---EYYAMLDATGNNVPKVDAEQAVRTYHAVSEATGAELVNSLQSPA 884
Query: 688 EGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKE 746
GGLA A ++ ++G +G E+ G S + LF E+ + + E+++AFE
Sbjct: 885 LGGLAVAFAKVAMAGRLGLEIDLAKVPAEGCSDLEVLFSESNSRFVATVAPEHKAAFEAA 944
Query: 747 MEGASIYEIGKTCGKAGLKL 766
+ G E+GK + L L
Sbjct: 945 LAGIPFAEVGKVIAEPELIL 964
>gi|58584529|ref|YP_198102.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
[Wolbachia endosymbiont strain TRS of Brugia malayi]
gi|58418845|gb|AAW70860.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
[Wolbachia endosymbiont strain TRS of Brugia malayi]
Length = 1045
Score = 480 bits (1236), Expect = e-133, Method: Composition-based stats.
Identities = 309/787 (39%), Positives = 433/787 (55%), Gaps = 56/787 (7%)
Query: 1 MNDEELLALSNER-----RAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
++D+EL +S + L + M+AI++++ R D E E++AQTWSEHC H
Sbjct: 251 VSDQELEKISRDGIDGNGTLGLSLTAMKAIKDYFNKLGRNPYDIELESLAQTWSEHCKHN 310
Query: 56 TFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFD 115
F + ID E K + + YIK+AT +I++ +S F DNAG I FD
Sbjct: 311 IFCSPID--------EIK--------DGLYAHYIKRATREINSNICMSVFSDNAGGIIFD 354
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDTPA 173
+ Y + K ETHN PSA++PFGGA TGV GV RD++G A P T CF
Sbjct: 355 DDYLIVDKVETHNSPSALDPFGGAMTGVLGVNRDIVGFGKGAEPIMNTYYFCFAKEAKGK 414
Query: 174 ----ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGI 229
+ L PK I+ VI GV GN GIPT G V++ + PLV+ G GI
Sbjct: 415 FYRDKERTDEILLPKYIMKEVIHGVNVAGNCSGIPTQLGSVYFDNRFCGKPLVFVGSVGI 474
Query: 230 APRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
PR H KP GD I+ +GG+ GRDG+ GATFSS +A +G+ + VQIG+P
Sbjct: 475 IPRNINNAPSHIKKPQNGDKIVIIGGRVGRDGIHGATFSS---EALSGNSPSTVVQIGDP 531
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPW 344
I QKK++ +I+ARD GLY+AITD GAGG SS++GEM G +VDL+K+ +K G+APW
Sbjct: 532 ITQKKLSNAVIEARDLGLYNAITDNGAGGLSSSIGEMGKD-GFEVDLSKVLLKSDGMAPW 590
Query: 345 ELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRF-GEKEIINLS 403
E+W+SE+QERM +AVP + L +++ +DVE++ +G F + VR I+N+
Sbjct: 591 EIWISESQERMTLAVPEENLPMFKQIMKKHDVEVSVIGEFNSTGMSTVRIHSASPIMNIE 650
Query: 404 CGFLHSGPPQRKLKAAP-PKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYD 462
FLH G P+ LK P K+ + LK +++ + SKE IV YD
Sbjct: 651 TEFLHDGNPKMHLKTKPWFKETTATLASRAGITLSQEVELKEMLSRPNICSKEFIVVQYD 710
Query: 463 HEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAI 522
HEVQG +VL+P G +G V +A V++P+ + K V S G +D Y AA AI
Sbjct: 711 HEVQGSSVLKPLQG-KGRVCSEAVVLRPILSSNKGVVK-SQGFGSSYGEIDTYHMAACAI 768
Query: 523 DEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKD 582
D A+RN VAAG + E A+LDNFC D PE +W L A +CY+ A+ FKTPFISGKD
Sbjct: 769 DTAIRNYVAAGGNIEHLALLDNFCWCDAYNPERLWQLKRAAEACYDYAIAFKTPFISGKD 828
Query: 583 SFNNEY--LSSEGKRV--SIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
S N++ GK+V S PPSLLISA+GI+ +I D K G IY++G
Sbjct: 829 SMFNDFKGYDENGKKVIISAPPSLLISAIGIIENIENAVSLDVKMPGDLIYMLGITHDEL 888
Query: 639 GGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEM 698
G S + GI + V K A +LYK + I + +V S L+ GGLA AL +
Sbjct: 889 GRSEYQLYSGIDNNNVPKVD--AKNARKLYKCFNQAIKESIVASAIALNLGGLAIALVKS 946
Query: 699 CLSG-IGAELKEDFH-TRLGASKIAS------LFGETTGCLLVEIKEENRSAFEKEMEGA 750
++G +GAE+ DF +G ++ +F E+ +LV I +N+ FE+ ++G
Sbjct: 947 LIAGDLGAEI--DFPLVPVGKTQNTDTINKIIMFSESQSRILVTIAPQNQKRFEELLKGT 1004
Query: 751 SIYEIGK 757
IG+
Sbjct: 1005 VYSCIGR 1011
>gi|150399926|ref|YP_001323693.1| Phosphoribosylformylglycinamidine synthase [Methanococcus vannielii
SB]
gi|150012629|gb|ABR55081.1| Phosphoribosylformylglycinamidine synthase [Methanococcus vannielii
SB]
Length = 993
Score = 475 bits (1223), Expect = e-132, Method: Composition-based stats.
Identities = 307/802 (38%), Positives = 445/802 (55%), Gaps = 71/802 (8%)
Query: 1 MNDEELLALSN---------ERRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWS 49
++DEEL+ + ERR ALDI + AI++++K E R D E E IAQTWS
Sbjct: 192 VSDEELIEIGKKGILDPDTLERRGPLALDIEYLTAIKDYFKKEGRNPNDIEIEAIAQTWS 251
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC H F ++ID E+ K+ I K YI+ AT++I + + +S
Sbjct: 252 EHCKHTIFASEID-------EDVKEG--------IFKKYIRNATNEIRKELGERDFCISV 296
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DN+G I FDE + V+ KAETHN PSA++PFGGA TG+ GV RD MG + A P A
Sbjct: 297 FSDNSGGIIFDENWMVTDKAETHNSPSALDPFGGAITGIVGVNRDTMGFGLGALPIANKY 356
Query: 163 VLCFGHPDTP-----AENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
C G P+ +N L PK+I+ GV+ GV GN GIPT G V++ ++Y
Sbjct: 357 GFCVGRPEDRNIVYRGKNKSNPALLPKKILEGVVHGVNVGGNHSGIPTPTGFVYFDDSYK 416
Query: 218 SNPLVYCGCAGIAPRG------KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
PLV+ G G+ PR H + GD+I+ +GG+ G+DG+ GATFSS MD +
Sbjct: 417 GKPLVFVGTIGLIPRKLPNGALSHEKQAQKGDNIVVIGGRVGKDGIHGATFSSEAMDEGS 476
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALG-CDV 329
++VQIG+PI QKK ++ +I +ARD GLY++ITD GAGG S +V EMA G V
Sbjct: 477 ---PATAVQIGDPITQKKASDAIIKEARDLGLYNSITDNGAGGISCSVAEMAKECGGFVV 533
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L K+P+KY GL PWE+W+SE+QER+ ++VP++KL +L VE +G+F
Sbjct: 534 ELEKVPLKYPGLEPWEIWISESQERITLSVPDEKLNEFMELMKIRGVESVVIGKFNETDR 593
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLN-----AALKA 444
V++ K I++L FLH G P++KL P K +EP++N +
Sbjct: 594 AVVKYNNKTIMDLDMEFLHEGLPKKKLHTIPYLYNK--------EEPEINIINHLEIFEK 645
Query: 445 VINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNA 504
++ +H S E I + YDHEVQ +V++P G G V A+VIKP+ T KK + +S +
Sbjct: 646 ILGNHNNCSFEYISKQYDHEVQNNSVVKPLQGI-GRVNGTASVIKPVLTS-KKGLVMSQS 703
Query: 505 LNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMAR 564
L PR ++ Y AA AID A+RN VA G + AI+DNFC + PE ++ L E AR
Sbjct: 704 LYPRLSEINCYDMAACAIDTAIRNCVAVGGNINHLAIMDNFCWCSSDEPERLFQLKETAR 763
Query: 565 SCYNTALVFKTPFISGKDSFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGSD 620
+CY+ A ++ TPFISGKDS N++ + ++S P+L+ISA+ ++ D+ +
Sbjct: 764 ACYDYAKIYLTPFISGKDSMFNDFKGFDENNNPIKISALPTLMISALSVIDDVENTNTME 823
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV 680
FK G +IY++GK GGS F F +S V K A +LY++++ ++
Sbjct: 824 FKLVGDSIYIIGKTYDECGGSEFYHAFSKLGSKSPKVD--AKYARKLYERIYELSNNKIL 881
Query: 681 LSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
SC ++ GG+ L +M ++G +GA + S L+ ET +V + EN
Sbjct: 882 SSCASVTLGGILITLSKMAIAGKLGAVIDSAVIPNESLSLEKILYSETQSRFIVTVAPEN 941
Query: 740 RSAFEKEMEGASIYEIGKTCGK 761
FEK ME I +IGK K
Sbjct: 942 EKEFEKLMEEFEIQKIGKVTEK 963
>gi|58696748|ref|ZP_00372289.1| phosphoribosylformylglycinamidine synthase II domain protein
[Wolbachia endosymbiont of Drosophila simulans]
gi|58537065|gb|EAL60193.1| phosphoribosylformylglycinamidine synthase II domain protein
[Wolbachia endosymbiont of Drosophila simulans]
Length = 963
Score = 475 bits (1223), Expect = e-132, Method: Composition-based stats.
Identities = 306/775 (39%), Positives = 427/775 (55%), Gaps = 49/775 (6%)
Query: 16 ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKA 75
L + MRAI++++K R D E E++AQTWSEHC H F + ID L E
Sbjct: 201 GLSLAAMRAIKDYFKKLGRNPYDIELESLAQTWSEHCKHNIFSSPIDEIKDGLYEH---- 256
Query: 76 YPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEP 135
YIK+AT +I++ +S F DNAG I FD+ Y + K ETHN PSA++P
Sbjct: 257 ------------YIKRATREINSDICVSVFSDNAGGIIFDDDYLIVDKVETHNSPSALDP 304
Query: 136 FGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDTPA----ENVPKGTLHPKRIISG 189
FGGA TGV GV RD++G A P T CF + L PK I+
Sbjct: 305 FGGAMTGVLGVNRDIVGFGKGAEPIMNTYYFCFAKEAKGKFYRDKERTDEILPPKYIMKE 364
Query: 190 VIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG-----KHRTKPSAGDH 244
VI GV GN GIPT G V++ + + PLV+ G GI PR H P GD
Sbjct: 365 VIHGVNVAGNCSGIPTQLGSVYFDDRFCGKPLVFVGSVGIIPRNINNAPSHIKGPKNGDK 424
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
I+ +GG+ GRDG+ GATFSS +A +G+ + VQIG+PI QKK++ +I ARD GLY+
Sbjct: 425 IVIIGGRVGRDGIHGATFSS---EALSGNSPSTIVQIGDPITQKKLSNAVIKARDLGLYN 481
Query: 305 AITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL 364
AITD GAGG SS++GEM G +VDL+K+ +K G+APWE+W+SE+QERM +AVP + L
Sbjct: 482 AITDNGAGGLSSSIGEMGKD-GFEVDLSKVLLKNDGMAPWEIWISESQERMTLAVPEENL 540
Query: 365 EALQKLCDANDVELTNLGRF--TGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPK 422
+++ +DVE+ +G F +G AV++ G I+++ FLH G P+ L+ P
Sbjct: 541 PMFKQIMKKHDVEVCVIGEFNESGKAVVKCPKGTV-IMDIGTEFLHDGNPKMHLQTKPWS 599
Query: 423 DGKPFIKYP-EYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNV 481
G P + P L LK +++ + SKE IV YDHEVQG +VL+P G +G +
Sbjct: 600 KGLPAPRAGMTTSSPSLEIELKEMLSRPNICSKEFIVVQYDHEVQGSSVLKPLQG-KGRM 658
Query: 482 PQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAI 541
+A V +P+ + K V S G +D Y AA AID A+RN VAAG + A+
Sbjct: 659 CSEAIVSRPVLSSNKGVVK-SQGFGSSYGEIDTYHMAACAIDTAIRNYVAAGGNINHLAL 717
Query: 542 LDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEY--LSSEGKRV--S 597
LDNFC D PE +W L + A +CY+ A FKTPFISGKDS N++ G++V S
Sbjct: 718 LDNFCWCDAYNPERLWQLKKAAEACYDFATAFKTPFISGKDSMFNDFKGYDENGEKVIIS 777
Query: 598 IPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAV 657
PPSLLISA+GI+ +I D K G IY++G+ G S + GI + V
Sbjct: 778 APPSLLISAIGIIENIENAVSLDVKMPGDLIYVLGETLDELGRSEYQLYSGIGNNNVPKV 837
Query: 658 PPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHT--R 714
K A +LY++ + I G++ S + GGL AL + ++G +GAE+ +
Sbjct: 838 D--AKSARKLYERYNQAIKDGIIASAIAPNLGGLVIALAKSLIAGDLGAEIDLSLVPIGK 895
Query: 715 LGASKIAS---LFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
+ + I + +F E+ +LV I +N+ FE+ EGA IGK K L +
Sbjct: 896 IQNTDIINKIIMFSESQSRILVTIAPQNQKRFEELFEGAVYSCIGKVTEKKVLNI 950
>gi|56417048|ref|YP_154122.1| phosphoribosylformylglycinamidine synthase [Anaplasma marginale
str. St. Maries]
gi|56388280|gb|AAV86867.1| phosphoribosylformylglycinamidine synthase [Anaplasma marginale
str. St. Maries]
Length = 1016
Score = 473 bits (1216), Expect = e-131, Method: Composition-based stats.
Identities = 303/803 (37%), Positives = 433/803 (53%), Gaps = 74/803 (9%)
Query: 1 MNDEELLALSN---ERRAALDIY--EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
++DEEL +S + R L++ M AIR ++ E RP D E ET+AQTWSEHC H
Sbjct: 220 VSDEELEKISKHGIDGRGPLNLSLEAMHAIRTYFDGENRPPNDIELETLAQTWSEHCKHN 279
Query: 56 TFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFD 115
F A+ID E K+ C IK+AT DI++P +S F DNAG I FD
Sbjct: 280 IFSAQID--------EIKEGLYRHC--------IKRATSDINSPMCISVFSDNAGAITFD 323
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPA 173
+ + V K ETHN PSA++PFGGA TGV GV RD++G + A+P + CF A
Sbjct: 324 DDFLVVAKVETHNSPSALDPFGGAETGVLGVNRDIIGFGMGAKPIMNSYHFCF------A 377
Query: 174 ENVPKG----------TLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVY 223
+N+ + L P++I GVI GV GN GIPT G ++ + PLV+
Sbjct: 378 DNLEQKLYRDRECLEEILPPRKIADGVIRGVNSGGNCSGIPTTIGTSYFDNRFCGKPLVF 437
Query: 224 CGCAGIAPRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
G GI PR H GD+I+ +GG+ GRDG+ GATFSS + G +
Sbjct: 438 VGSIGIIPRTVCGLPAHVKTVQDGDYIVVVGGRVGRDGIHGATFSSHALREGIG---ATV 494
Query: 279 VQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVK 337
VQ+G PI QKK+++ +I ARD GLY+AITD GAGG SS+VGEM G +V+L K+P+K
Sbjct: 495 VQVGSPITQKKLSDAIIKQARDLGLYNAITDNGAGGLSSSVGEMG-VRGFNVELDKVPLK 553
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
Q + PWE+W+SE+QERM +AVP K + L ++ +DVE++ +G F V + K
Sbjct: 554 TQSMLPWEIWVSESQERMTLAVPPSKYQKLAEIMQMHDVEISIIGEFNSTGRAVVTYNGK 613
Query: 398 EIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYK---EPDLNAALKAVINHHAVNSK 454
I+++ FLH+G P+ L K F + + + L+ +I + SK
Sbjct: 614 VIMDIDTSFLHNGVPRLTLTTE-----KQFYTQQQSELRTNTSVAEDLRNIIGRKNICSK 668
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E I+ YDHEVQG +V++P G G + DA V++P+ + K+ V S R G +DP
Sbjct: 669 EYIISQYDHEVQGSSVIKPLQGA-GRICGDAVVLRPVPSS-KRGVVTSQGFGCRYGEVDP 726
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFK 574
Y AA AID A+RN VA G + + A++DNFC P +W L + AR+CY+ A F
Sbjct: 727 YRMAACAIDTAIRNYVAVGGNIDHLALIDNFCWCSATEPGRLWQLKQAARACYDYATAFG 786
Query: 575 TPFISGKDSFNNEY--LSSEGK--RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYL 630
TPFISGKDS N++ +S G+ R+S PPSLLIS +GI+ ++ S K IY+
Sbjct: 787 TPFISGKDSMFNDFHGYNSAGQPVRISAPPSLLISTLGIIENVENAI-SPHVKGMDPIYI 845
Query: 631 VGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSCHDLSEG 689
+G G S + G+ SG +VP + A+L Y+K H ++G++ S G
Sbjct: 846 LGTTYNELGMSEYQAYSGLNSG---SVPSVDAQTAKLMYRKFHHATIRGIIASAIAPGLG 902
Query: 690 GLAAALYEMCLSG-IGAELKEDFHTRLGASK-----IASLFGETTGCLLVEIKEENRSAF 743
GLA L + + G +GAE+ G K + +F E+ ++V + E+ + F
Sbjct: 903 GLAVGLAKALIGGRLGAEIDLSAVPTSGIPKDEMWEKSIMFSESQSRIIVTVHEDRSAEF 962
Query: 744 EKEMEGASIYEIGKTCGKAGLKL 766
E IG+T LK+
Sbjct: 963 ESIFSEVPHARIGRTTKDYMLKI 985
>gi|149199267|ref|ZP_01876305.1| phosphoribosylformylglycinamidine synthase [Lentisphaera araneosa
HTCC2155]
gi|149137692|gb|EDM26107.1| phosphoribosylformylglycinamidine synthase [Lentisphaera araneosa
HTCC2155]
Length = 997
Score = 471 bits (1213), Expect = e-131, Method: Composition-based stats.
Identities = 304/790 (38%), Positives = 434/790 (54%), Gaps = 57/790 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRP----------CTDAEFETIAQTWSE 50
++DEEL+ +SN + AL + EM+AIR++ TDAE E +AQ+WSE
Sbjct: 195 VSDEELMGISNSKTLALQLDEMQAIRDYAINNNDAQREELGLIGKLTDAELECLAQSWSE 254
Query: 51 HCVHKTFKAKI---DIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI--DAPWVLSSF 105
HC HK F A I D DG T +NS+ K+YIKK+T +I W++S F
Sbjct: 255 HCSHKIFAADIEYTDADGNVET-----------INSLYKSYIKKSTFEIGDQVDWLVSVF 303
Query: 106 VDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDV-- 163
DNAG+I F+EKY+++FK ETHN PSA++P+GGA TG+ GV RD+MG + +V
Sbjct: 304 HDNAGVITFNEKYDLAFKLETHNSPSALDPYGGAMTGIVGVNRDIMGTGTGAEMLVNVWG 363
Query: 164 LCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVY 223
C G P VP+G LHP+RI GV +GV + GN+ GIP G ++ Y PLVY
Sbjct: 364 YCLGSPFVDESEVPEGLLHPRRIRDGVHQGVIEGGNQSGIPYGLGWEYFDARYIGKPLVY 423
Query: 224 CGCAGIAPRGKHRTKPS-----AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
CG GI P +H S GD I+ +GG+ G+DG+ GATFSS + D ++
Sbjct: 424 CGTVGILPHKQHGKSASLKTIEPGDVIVMVGGRIGKDGIHGATFSSEELHK---DSPVAA 480
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVDLAKIPVK 337
VQIG+PI QKK A+ L +ARD LY +TD GAGG SS++GEMA+ GC VDLAK P+K
Sbjct: 481 VQIGDPITQKKAADFLYEARDADLYRFVTDNGAGGLSSSIGEMATECNGCFVDLAKAPLK 540
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
Y GL PWE+++SEAQERM AVP +K+EA L DVE T LG F + + +
Sbjct: 541 YAGLQPWEIFVSEAQERMSFAVPVEKVEAFLTLAQERDVEATVLGEFNDSGKCHLIYNDL 600
Query: 398 EIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDI 457
+ L F+H G P+ +LKA + F + PE + +++ + ++ + S E
Sbjct: 601 TVAFLDLDFMHGGNPKLQLKAK--WEAPVFEEIPEELDSEISDDIHELLASLNLCSSEYK 658
Query: 458 VRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPMETEGKKAVAISNALNPRQGLLDPY 515
R YDHEV+ +V++PY G E +V DA+V +PM EG ++N + P +D Y
Sbjct: 659 ARQYDHEVKALSVVKPYVGVEADVDSDASVFMAEPMTKEG---FVLANGVAPSYSDIDTY 715
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMARS---CYN 568
AS ID +R VA G +K A LDNFC DP P+ + L ++ RS Y+
Sbjct: 716 HMTASIIDMCLRRTVAVGGSIDKVAGLDNFCWPDPVESAKTPDGQYKLAQLVRSNQALYD 775
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
F P ISGKDS N+ + GK++SIPP+LL S + + D+ + K+ G +
Sbjct: 776 YCKAFTLPCISGKDSMKNDS-TRGGKKISIPPTLLFSTIAPMMDVSKSVTLSSKRAGDYV 834
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKE-AAELYKKLHSNIMKGLVLSCHDLS 687
Y++G+ GGS +A G + VP E A ++YK++H +V S H +
Sbjct: 835 YVIGETLAELGGSQYAAQKGYVGNK---VPQVDAEKAKKIYKQVHQATDAEVVHSLHAPA 891
Query: 688 EGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKE 746
GGLAAA ++G +G E+ + S+ LF E+ L+ + + FE
Sbjct: 892 FGGLAAAFARKSIAGRLGMEIDINLIPADDLSETELLFSESNSRLVATVAPDKAEEFEAL 951
Query: 747 MEGASIYEIG 756
+EG + ++G
Sbjct: 952 LEGVAFAKVG 961
>gi|68171200|ref|ZP_00544606.1| Phosphoribosylformylglycinamidine synthase [Ehrlichia chaffeensis
str. Sapulpa]
gi|88657843|ref|YP_507171.1| putative phosphoribosylformylglycinamidine synthase II [Ehrlichia
chaffeensis str. Arkansas]
gi|67999394|gb|EAM86037.1| Phosphoribosylformylglycinamidine synthase [Ehrlichia chaffeensis
str. Sapulpa]
gi|88599300|gb|ABD44769.1| putative phosphoribosylformylglycinamidine synthase II [Ehrlichia
chaffeensis str. Arkansas]
Length = 1007
Score = 471 bits (1211), Expect = e-130, Method: Composition-based stats.
Identities = 294/789 (37%), Positives = 437/789 (55%), Gaps = 57/789 (7%)
Query: 1 MNDEELLALS----NERRAA-LDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
+ D EL+ +S N R A L + M+AI+ ++K +R D E ET+AQTWSEHC H
Sbjct: 211 IQDHELIQISKHGINGRGALNLSLEAMKAIQAYFKKIQRNPNDIELETLAQTWSEHCKHN 270
Query: 56 TFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFD 115
F + ID +T+ + K YIK+AT +I++ +S+F DNAG I FD
Sbjct: 271 IFSSPID----EITD------------GLYKHYIKRATYEINSEICVSTFSDNAGAIVFD 314
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDTPA 173
+ + ++ K ETHN PSA++PFGGA TG+ GV RD++G A+P CF D
Sbjct: 315 DNFIIADKVETHNSPSALDPFGGAITGILGVNRDIIGFGKGAKPILNAYYFCFSESDEEL 374
Query: 174 ---ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIA 230
++ L I+ GVI+GV GN GIPT G ++ + S PLV+ GC GI
Sbjct: 375 YRDKSCTTKVLSSNTIMDGVIKGVNYGGNCSGIPTSLGSAYFDNRFRSKPLVFVGCTGIM 434
Query: 231 PRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
PR H P+ GD+I+ GG+TGRDG+ GATFSS + + + + + VQIG+PI
Sbjct: 435 PRTINKSLSHVKNPNNGDYIVIAGGRTGRDGIHGATFSSNAL--TEHNSSSTVVQIGDPI 492
Query: 286 IQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPW 344
QKK+++ +I +ARD LY+AITD GAGG SS++GEM + G V+L K+ +K+ ++PW
Sbjct: 493 TQKKLSDAIIKEARDLDLYNAITDNGAGGLSSSIGEMGNN-GFIVELDKVLLKHDNMSPW 551
Query: 345 ELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSC 404
E+W+SE+QERM AV +K +K+ +D+E++ +G F V F I+++
Sbjct: 552 EIWVSESQERMTFAVSPNKFSIFEKVMKKHDIEISIIGEFNNSNKAVVLFKGSVIMDIDV 611
Query: 405 GFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHE 464
FLH+G P+ L +P I +P+ L L +I + SKE I YDHE
Sbjct: 612 DFLHNGVPKIHLHTSPWSKTTESI-FPKKHNKPLEIELNEMIQRMNICSKEFISLQYDHE 670
Query: 465 VQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDE 524
VQG ++++P G +G V DA VIKP+ + KK + S+ L G + Y AA AID
Sbjct: 671 VQGTSIIKPIQG-KGRVNGDATVIKPILSS-KKGIVKSHGLGSSYGEISTYHMAACAIDT 728
Query: 525 AVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSF 584
A+RN +A G + A+LDNFC D P+ +W L A++CY+ A+ F+TPFISGKDS
Sbjct: 729 AIRNYIAVGGNFNHLALLDNFCWCDSTNPQRLWQLKNAAQACYDYAIAFRTPFISGKDSM 788
Query: 585 NNEY--LSSEGKRVSI--PPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
N++ +++GK ++I PPSLLIS +GI+ ++ D K G IY++G G
Sbjct: 789 FNDFKGYNNKGKEINISAPPSLLISTLGIIENVENAVTLDVKSPGDLIYILGTTYDELGS 848
Query: 641 SVFAELFGIPSGESAAVPPFKKE-AAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC 699
S + + G+ + VP E A +LY + I L+ S ++ GG+ +L +
Sbjct: 849 SEYQKYSGLGNNN---VPQVHAEHAKKLYISYNKAINTNLIASAIAVNLGGMIISLIKSL 905
Query: 700 LSG-IGAELK------EDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFE---KEMEG 749
+ G +GAE+ + K+ LF E+ +LV I E N+ FE KE+
Sbjct: 906 IGGQLGAEISLSAIPTYNIDNNTLREKVI-LFSESQSRILVTIGEHNKQRFEAIFKEVPY 964
Query: 750 ASIYEIGKT 758
A+I ++ T
Sbjct: 965 ANIGKVTST 973
>gi|58617401|ref|YP_196600.1| Phosphoribosylformylglycinamidine synthase II [Ehrlichia
ruminantium str. Gardel]
gi|58417013|emb|CAI28126.1| Phosphoribosylformylglycinamidine synthase II [Ehrlichia
ruminantium str. Gardel]
Length = 1010
Score = 470 bits (1209), Expect = e-130, Method: Composition-based stats.
Identities = 295/794 (37%), Positives = 437/794 (55%), Gaps = 67/794 (8%)
Query: 1 MNDEELLALSN---ERRAALDIY--EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
+ DEEL+ LS R L++ M+AI+ ++K R D E ET+AQTWSEHC H
Sbjct: 211 IQDEELMKLSKYGIHGRGGLNLSLEAMKAIQAYFKKINRNPNDIELETLAQTWSEHCKHN 270
Query: 56 TFKAKID--IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIE 113
F + ID IDG + K YIK+AT +I++ +S+F DNAG I
Sbjct: 271 IFSSPIDDIIDG------------------LYKHYIKRATYEINSEICVSTFSDNAGAII 312
Query: 114 FDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDT 171
FD+ + ++ K ETHN PSA++PFGGA TG+ GV RD++G A+P CF +
Sbjct: 313 FDDNFIIADKVETHNSPSALDPFGGAITGILGVNRDIIGFGKGAKPILNAYYFCFSESEK 372
Query: 172 PA---ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAG 228
+ L + II+GVI+GV GN GIPT G V++ + + S PLV+ GC G
Sbjct: 373 ELYRDKMCTVSVLPSETIINGVIKGVNSGGNCSGIPTGLGSVYFDDRFQSKPLVFVGCTG 432
Query: 229 IAPR-----GKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGE 283
I PR H P+ GD+I+ GG+TGRDG+ GATFSS + + + + VQIG+
Sbjct: 433 IIPRIIGNTPSHLKGPADGDYIVIAGGRTGRDGIHGATFSSNALTENNSN--STVVQIGD 490
Query: 284 PIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLA 342
PI QKK+++ +I +ARD LY+AITD GAGG SS++GEM + G V+L K+ +K++ +
Sbjct: 491 PITQKKLSDAIIKEARDLNLYNAITDNGAGGLSSSIGEMGNN-GFKVELNKVLLKHKNML 549
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
PWE+W+SE+QERM +A+P K +K+ +DVE++ +G F V + + I+++
Sbjct: 550 PWEIWVSESQERMTLAIPPSKFPIFEKIMKKHDVEISIIGTFNNTKKAVVSYNDSIIMDM 609
Query: 403 SCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYD 462
FLH+G P+ LK P + + +P L+ L ++ + SKE I YD
Sbjct: 610 DINFLHNGIPKTHLKTIPWSNIISSAVDTLHNKP-LDTELNEMMQRMNICSKEFISTQYD 668
Query: 463 HEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAI 522
HEVQG +V++P G +G V +A VI+P+ + ++ + S+ L G + Y AA AI
Sbjct: 669 HEVQGTSVIKPIQG-KGRVDGEAIVIRPILSS-ERGLVKSHGLGSSYGEISTYHMAACAI 726
Query: 523 DEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKD 582
D A+RN +A G + A+LDNFC D P+ +W L A++CYN A +FKTPFISGKD
Sbjct: 727 DTAIRNYIAIGGNFHHLALLDNFCWCDSTNPKRLWQLKNAAQACYNYAKIFKTPFISGKD 786
Query: 583 SFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
S N++ K +S PPSLLIS +GI+ +I D K G IY++G
Sbjct: 787 SMFNDFKGYNNKGEPINISAPPSLLISTVGIIENIHNAITLDVKNPGDLIYILGVTYDEL 846
Query: 639 GGSVFAELFGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
G S + + G+ + VP + K A +LYK + + ++ S L+ GGL L +
Sbjct: 847 GRSEYQKYSGLGNNN---VPQVRAKHAKKLYKLYSNAVNTNIIASAIALNLGGLIIGLIK 903
Query: 698 MCLSG-IGAELK---------EDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFE--- 744
+ G +GA++ ED + + + LF E+ +LV I N+ FE
Sbjct: 904 SLIGGELGAKIDLSLVPTHNIEDNNIK----EKVILFSESQSRILVTIAPHNKQKFETIF 959
Query: 745 KEMEGASIYEIGKT 758
K++ A+I I T
Sbjct: 960 KDITHANIGIISDT 973
>gi|126179575|ref|YP_001047540.1| Phosphoribosylformylglycinamidine synthase [Methanoculleus
marisnigri JR1]
gi|125862369|gb|ABN57558.1| Phosphoribosylformylglycinamidine synthase [Methanoculleus
marisnigri JR1]
Length = 979
Score = 469 bits (1208), Expect = e-130, Method: Composition-based stats.
Identities = 296/774 (38%), Positives = 430/774 (55%), Gaps = 48/774 (6%)
Query: 10 SNERRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTS 67
+ ERR ALD+ ++ AIR++++ R TD E E++AQTWSEHC H F + +D
Sbjct: 203 TGERRGPLALDLAQLHAIRDYFRGLGRKPTDVELESLAQTWSEHCKHTIFASAMD----- 257
Query: 68 LTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETH 127
+ + C+ + T +++A D D +S F DN+G I FD+++ V+ K ETH
Sbjct: 258 ---DVPRGLYKTCIQAATNT-VREAKGDDDI--CVSVFTDNSGAIIFDDEHLVTCKVETH 311
Query: 128 NHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDT-PA----ENVPKGT 180
N PSA++PFGGA TG+ GV RD +G + A+P C G PDT PA +N
Sbjct: 312 NSPSALDPFGGALTGIVGVNRDTIGFGLGAKPCINIYGYCVGDPDTEPALFRGKNRTNPI 371
Query: 181 LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-----H 235
L P+RI GV+ G+ GN GIPT G ++H+ Y PLV+ G G+ PR H
Sbjct: 372 LPPRRIFEGVVRGIDVGGNCSGIPTPQGWCYFHDRYVGKPLVFAGTVGVMPRANNGRLLH 431
Query: 236 RTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLI 295
+ GD ++ +GG+ G+DG+ GATFSS +D ++ A VQIG+PI QKK ++V++
Sbjct: 432 EKQALPGDLVVMVGGRVGKDGIHGATFSSEALDPASPVTA---VQIGDPITQKKFSDVIV 488
Query: 296 -DARDQGLYSAITDCGAGGYSSAVGEMA-SALGCDVDLAKIPVKYQGLAPWELWLSEAQE 353
+ARD LY +ITD GAGG S +V EMA + GC V L ++P+KY G+APWE+W+SE+QE
Sbjct: 489 KEARDLDLYRSITDNGAGGISCSVAEMARESGGCHVLLDRVPLKYPGMAPWEIWISESQE 548
Query: 354 RMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQ 413
RM +AVP +K+EA L +VE T +G FT V +G + ++++ FLH G P+
Sbjct: 549 RMTLAVPEEKIEAFMDLMKRREVEATVIGTFTDTGRCVVEYGGETVMDVDLDFLHDGLPK 608
Query: 414 RKLKAAPPKDGKPFIKYPEYKEPD-LNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLR 472
+ L+ P + P P++ PD L+ L A++ + SKE I YDH VQGG VL
Sbjct: 609 KHLRTEPVETAYP---EPDFPCPDRLDDLLLAMLARKNICSKEFISTRYDHTVQGGHVLG 665
Query: 473 PYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAA 532
P G G V Q A + + K V +S L P LDPY A +AID AVR +A
Sbjct: 666 PVQGA-GRV-QTTATLTKVVPGSMKGVGLSQGLFPSYSELDPYRMALAAIDAAVRGLIAI 723
Query: 533 GADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEY---- 588
G + A+LDNFC + P +W L A CY+ A+ F TP+ISGKDS N++
Sbjct: 724 GVPLDTIALLDNFCWCSSDEPARLWQLKRAAFGCYDGAVEFATPYISGKDSMFNDFSGYD 783
Query: 589 LSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFG 648
S +VS+PP+LLI+++G+ PD+ D K +G +Y+VG+ GGS + G
Sbjct: 784 ADSNPVKVSVPPTLLITSIGVHPDVTTAVSMDAKFDGDLVYVVGETGEELGGSEYLAHLG 843
Query: 649 IPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAEL 707
+ E VP E A++ Y ++ I K L+ S ++ GGL AL ++ ++G
Sbjct: 844 V---EGGTVPSLDIETAKVRYGRMTGAIEKNLLASAFPVTHGGLLVALAKVAIAGRAG-- 898
Query: 708 KEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCGK 761
D G LF E+ G L+V + +R AFE E+ G + +G G+
Sbjct: 899 -MDLTITGGMRPDTYLFSESLGRLIVTVAPGDREAFE-EIFGGDAHLLGSVGGE 950
>gi|73667272|ref|YP_303288.1| Phosphoribosylformylglycinamidine synthase [Ehrlichia canis str.
Jake]
gi|72394413|gb|AAZ68690.1| Phosphoribosylformylglycinamidine synthase [Ehrlichia canis str.
Jake]
Length = 1004
Score = 469 bits (1208), Expect = e-130, Method: Composition-based stats.
Identities = 292/788 (37%), Positives = 431/788 (54%), Gaps = 60/788 (7%)
Query: 1 MNDEELLALS-----NERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
+ D +L+ +S N L + M+AI+ ++K +R D E ET+AQTWSEHC H
Sbjct: 209 IQDHKLIQISKHGINNRGPLNLSLEAMKAIQAYFKKIQRNPNDIELETLAQTWSEHCKHN 268
Query: 56 TFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFD 115
F + ID +T+ + K YIK+AT +I++ +S+F DNAG I FD
Sbjct: 269 IFSSPID----EITD------------GLYKHYIKRATQEINSEICVSTFSDNAGAIIFD 312
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDTPA 173
+ + ++ K ETHN PSA++PFGGA TG+ GV RD++G A+P CF +
Sbjct: 313 DNFIIADKVETHNSPSALDPFGGAITGILGVNRDIIGFGKGAKPILNAYYFCFSESEEEL 372
Query: 174 ---ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIA 230
++ L I+ GVI+GV GN GIPT G ++ + + S PLV+ GC GI
Sbjct: 373 YRDKSCTVKVLPSDVIMDGVIKGVNSGGNCSGIPTSLGSAYFDDRFRSKPLVFVGCTGIM 432
Query: 231 PRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
PR H KP+ GD I+ GG+TGRDG+ GATFSS + + + + + VQIG+PI
Sbjct: 433 PRTINNALSHLKKPNNGDFIVIAGGRTGRDGIHGATFSSNAL--TEHNSSSTVVQIGDPI 490
Query: 286 IQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPW 344
QKK+++ +I +ARD LY+AITD GAGG SS+VGEM + G V+L K+ +K+ + PW
Sbjct: 491 TQKKLSDAIIKEARDLDLYNAITDNGAGGLSSSVGEMGNN-GFRVELDKVLLKHDNMLPW 549
Query: 345 ELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSC 404
E+W+SE+QERM AVP +K +K+ +DVE++ +G F V + I+++
Sbjct: 550 EIWVSESQERMTFAVPPNKFTMFEKVMKKHDVEISIIGEFNNTNKAVVLYKGSVIMDMDV 609
Query: 405 GFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHE 464
FLH+G P+ L+ I ++ +P L L +I + SKE I YDHE
Sbjct: 610 DFLHNGVPKIHLQTNSYTQTIESIPNKKFNKP-LAVELNEIIQRMNICSKEFISLQYDHE 668
Query: 465 VQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDE 524
VQG +V++P G +G V DA VI+P+ + + V S L G + Y AA AID
Sbjct: 669 VQGTSVIKPLQG-KGRVNGDATVIRPILSSNRGIVK-SQGLGSSYGEISTYHMAACAIDT 726
Query: 525 AVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSF 584
A+RN VA G + A+LDNFC D P+ +W L A++CY+ A+ FKTPFISGKDS
Sbjct: 727 AIRNYVAVGGNFNHLALLDNFCWCDSTNPQRLWQLKNAAKACYDYAVAFKTPFISGKDSM 786
Query: 585 NNEY--LSSEGKRVSI--PPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
N++ + +G+ ++I PPSLLIS +GI+ ++ D K G IY++G GG
Sbjct: 787 FNDFKGYNKKGEEITISAPPSLLISTIGIIENVENAVTLDVKSPGDLIYILGITYNELGG 846
Query: 641 SVFAELFGIPSGESAAVPPFKKE-AAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC 699
S + + GI E+ VP E A +LY + I L+ S ++ GG+ +L +
Sbjct: 847 SEYQKYTGI---ENNNVPQVHAEHAKKLYTSYNKAISANLIASAIAINLGGIIISLVKSL 903
Query: 700 LSG-IGAELK---------EDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
+ G +GAE+ E+ H + + LF E+ +LV + E + FE +
Sbjct: 904 IGGQLGAEISLSSIPICNIENNHLQ----EKVILFSESQSRILVTVNENKKQEFETIFKN 959
Query: 750 ASIYEIGK 757
IGK
Sbjct: 960 IPHANIGK 967
>gi|88602352|ref|YP_502530.1| phosphoribosylformylglycinamidine synthase II [Methanospirillum
hungatei JF-1]
gi|88187814|gb|ABD40811.1| phosphoribosylformylglycinamidine synthase II [Methanospirillum
hungatei JF-1]
Length = 979
Score = 469 bits (1206), Expect = e-130, Method: Composition-based stats.
Identities = 309/799 (38%), Positives = 433/799 (54%), Gaps = 70/799 (8%)
Query: 1 MNDEELLALSNE---------RRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWS 49
++D+EL+ + E RR ALD+ ++ AIR++++ + R TD E E++AQTWS
Sbjct: 184 VDDQELIRIGKEGIIDAETGQRRGPLALDLVQLHAIRDYFQAQGRKPTDVEIESLAQTWS 243
Query: 50 EHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSS 104
EHC H F + +D D + KT I+ AT+ I D LS
Sbjct: 244 EHCKHTIFASPMDDDMP---------------RGLYKTCIQAATNTIRAQKGDKDICLSV 288
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTD 162
F DN+G I FD+ Y V+ K ETHN PSA++PFGGA TG+ GV RD +G + A+P
Sbjct: 289 FSDNSGAIIFDDHYLVTHKVETHNSPSALDPFGGALTGIVGVNRDTIGFGLGAKPCINIY 348
Query: 163 VLCFGHPDTP-----AENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
C G P++ +N L P+RI+ GV+ GV GN GIPT G V + + Y
Sbjct: 349 GFCVGDPESNPVLYRGKNRSNPILSPRRILDGVVSGVGVGGNCSGIPTPQGFVWFDDRYV 408
Query: 218 SNPLVYCGCAGIAPRGK-----HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTG 272
PLV+ G GI PR + + GD I+ +GG+ G+DG+ GATFSS +D +
Sbjct: 409 GKPLVFAGTVGIMPRTDGTRKLYEKQARPGDLIVMIGGRVGKDGIHGATFSSEALDPKSP 468
Query: 273 DVAGSSVQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVD 330
A VQIG+PI QKK+++V++ +ARD+GLY++ITD GAGG S +V EMA GC V
Sbjct: 469 VTA---VQIGDPITQKKLSDVIVKEARDRGLYTSITDNGAGGISCSVAEMAKECNGCHVL 525
Query: 331 LAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVL 390
L K+P+KY G+APWE+W+SE+QERM +AVP +KL+ L + DVE T +G FT
Sbjct: 526 LDKVPLKYPGMAPWEIWISESQERMTLAVPPEKLDEFMDLLASRDVEATVIGTFTNTGRC 585
Query: 391 RVRFGEKEIINLSCGFLHSGPPQRKLKAAP--PKDGKPFIKYPEYKEPDLNAALKAVINH 448
V + ++++ FLH G P ++LK P P P PE L+ LK ++
Sbjct: 586 IVEYHGSVVMDIELSFLHDGVPVKQLKTEPTVPVPSDPMPPCPE----QLDLILKEMLAR 641
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
+ SKE I YDH VQGG VL P GP G V Q A + + KK V +S + P
Sbjct: 642 KNICSKEFISIQYDHTVQGGHVLGPVQGP-GRV-QGMATLMKVVPGSKKGVGLSQGIFPS 699
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
+D Y A + ID A+R +A G + AILDNFC + P+ + L AR CY+
Sbjct: 700 YSEIDSYRMAIACIDTAIRGLIALGIPLDAIAILDNFCWCSSDDPKRLAQLKAAARGCYD 759
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKR----VSIPPSLLISAMGIVPDIGRVPGSDFKKE 624
A F+TPFISGKDS N++ +G+ VS+PP+LLIS++GI PD+ + D K E
Sbjct: 760 GATGFETPFISGKDSMFNDFRGYDGESNPVLVSVPPTLLISSIGIHPDVTKAVSLDAKIE 819
Query: 625 GSAIYLVGKPQFSFGGSVFAELFGIPSGESAA--VPPFKKEAAELYKKLHSNIMKGLVLS 682
G +YL+G+ + GGS +A I G A +P K Y +L I+ LV S
Sbjct: 820 GDLVYLIGENRDELGGSEYAAHLNISGGIVPAIDIPAMKAR----YHRLTHAILHDLVAS 875
Query: 683 CHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
++ GGLA AL ++ IG +L D LF ET G +V + + + +
Sbjct: 876 AFPVTHGGLAVALAKV---AIGGKLGMDVTLSGDLRSDVLLFSETLGRFIVTVDPDKKRS 932
Query: 743 FEKEMEGASIYEIGKTCGK 761
FE M G+ IG+ GK
Sbjct: 933 FELAM-GSDATLIGRVTGK 950
>gi|57239379|ref|YP_180515.1| putative phosphoribosylformylglycinamidine synthase II [Ehrlichia
ruminantium str. Welgevonden]
gi|58579347|ref|YP_197559.1| Phosphoribosylformylglycinamidine synthase II [Ehrlichia
ruminantium str. Welgevonden]
gi|57161458|emb|CAH58383.1| putative phosphoribosylformylglycinamidine synthase II [Ehrlichia
ruminantium str. Welgevonden]
gi|58417973|emb|CAI27177.1| Phosphoribosylformylglycinamidine synthase II [Ehrlichia
ruminantium str. Welgevonden]
Length = 1010
Score = 468 bits (1203), Expect = e-130, Method: Composition-based stats.
Identities = 295/793 (37%), Positives = 432/793 (54%), Gaps = 65/793 (8%)
Query: 1 MNDEELLALSN---ERRAALDIY--EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
+ DEEL+ LS R L++ M+AI+ ++K R D E ET+AQTWSEHC H
Sbjct: 211 IQDEELMELSKYGIHGRGGLNLSLEAMKAIQAYFKKINRNPNDIELETLAQTWSEHCKHN 270
Query: 56 TFKAKID--IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIE 113
F + ID IDG + K YIK+AT +I++ +S+F DNAG I
Sbjct: 271 IFSSPIDDIIDG------------------LYKHYIKRATYEINSEICVSTFSDNAGAII 312
Query: 114 FDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDT 171
FD+ + ++ K ETHN PSA++PFGGA TG+ GV RD++G A+P CF +
Sbjct: 313 FDDNFIIADKVETHNSPSALDPFGGAITGILGVNRDIIGFGKGAKPILNAYYFCFSESEK 372
Query: 172 PA---ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAG 228
+ L + II+GVI+GV GN GIPT G V++ + + S PLV+ GC G
Sbjct: 373 ELYRDKMCTVSVLPSETIINGVIKGVNSGGNCSGIPTGLGSVYFDDRFQSKPLVFVGCTG 432
Query: 229 IAPR-----GKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGE 283
I PR H P+ GD+I+ GG+TGRDG+ GATFSS + + + + VQIG+
Sbjct: 433 IIPRIIGNTPSHLKGPADGDYIVIAGGRTGRDGIHGATFSSNALTENNSN--STVVQIGD 490
Query: 284 PIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLA 342
PI QKK+++ +I +ARD LY+AITD GAGG SS++GEM + G V+L K+ +K++ +
Sbjct: 491 PITQKKLSDAIIKEARDLNLYNAITDNGAGGLSSSIGEMGNN-GFKVELNKVLLKHKNML 549
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
PWE+W+SE+QERM +A+P K +K+ +DVE++ +G F V + + I+++
Sbjct: 550 PWEIWVSESQERMTLAIPPSKFPIFEKIMKKHDVEISIIGTFNNTKKAVVSYNDSIIMDI 609
Query: 403 SCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYD 462
FLH+G P+ LK P + + +P L+ L ++ + SKE I YD
Sbjct: 610 DINFLHNGIPKTHLKTIPWSNIISSAVDTLHNKP-LDTELNEMMQRMNICSKEFISTQYD 668
Query: 463 HEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAI 522
HEVQG +V++P G +G V +A VI+P+ + ++ + S+ L G + Y AA AI
Sbjct: 669 HEVQGTSVIKPIQG-KGRVDGEAIVIRPILSS-ERGLVKSHGLGSSYGEISTYHMAACAI 726
Query: 523 DEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKD 582
D A+RN +A G + A+LDNFC D P+ +W L A++CY+ A +FKTPFISGKD
Sbjct: 727 DTAIRNYIAIGGNFHHLALLDNFCWCDSTNPKRLWQLKNAAQACYDYAKIFKTPFISGKD 786
Query: 583 SFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
S N++ K +S PPSLLIS +GI+ +I D K G IY++G
Sbjct: 787 SMFNDFKGYNNKGEPINISAPPSLLISTVGIIENIHNAITLDVKNPGDLIYILGVTYDEL 846
Query: 639 GGSVFAELFGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
G S + + G+ + VP + K A +LYK + + ++ S L+ GGL L +
Sbjct: 847 GRSEYQKYSGLGNNN---VPQVRAKHAKKLYKLYSNAVNTNIISSAIALNLGGLVIGLIK 903
Query: 698 MCLSGIGAELKEDFHTRL---------GASKIASLFGETTGCLLVEIKEENRSAFE---K 745
S IG EL L + LF E+ +LV I N+ FE K
Sbjct: 904 ---SLIGGELGAKIDLSLVPTHNIEDNSIKEKVILFSESQSRILVTIAPHNKQKFETIFK 960
Query: 746 EMEGASIYEIGKT 758
++ A+I I T
Sbjct: 961 DIAHANIGIISDT 973
>gi|154150015|ref|YP_001403633.1| Phosphoribosylformylglycinamidine synthase [Candidatus
Methanoregula boonei 6A8]
gi|153998567|gb|ABS54990.1| Phosphoribosylformylglycinamidine synthase [Candidatus
Methanoregula boonei 6A8]
Length = 982
Score = 466 bits (1199), Expect = e-129, Method: Composition-based stats.
Identities = 309/794 (38%), Positives = 429/794 (54%), Gaps = 64/794 (8%)
Query: 3 DEELLALSNE---------RRA--ALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEH 51
DE+LL L E RR ALD+ ++ AIR ++ R TD E E++AQTWSEH
Sbjct: 187 DEDLLRLGKEGISDPQTGQRRGPLALDLAQLHAIRNYFDRAGRKPTDVEIESLAQTWSEH 246
Query: 52 CVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI-----DAPWVLSSFV 106
C H F + +D D + K++I+ AT++I D ++ F
Sbjct: 247 CKHTIFASAMDDD---------------VPKGLYKSFIQAATNEIRAEKGDRDICVTVFT 291
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVL 164
DN+G I FD++Y V+ K ETHN PSA++PFGGA TG+ GV RD +G + A+P
Sbjct: 292 DNSGAIVFDDEYLVTHKVETHNSPSALDPFGGALTGIVGVNRDTIGFGLGAKPCINVYGF 351
Query: 165 CFGHPDT-PA----ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
C G P + PA + + P++I+ GV+ GV GN GIPT G + YA
Sbjct: 352 CVGDPASEPALYRGRDRKNPIISPRQILDGVVRGVGVGGNCSGIPTPQGFCWFDNRYAGK 411
Query: 220 PLVYCGCAGIAPRGKH-----RTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLV+ G G+ PR + K GD I+ +GG+ G+DG+ GATFSS +D ++
Sbjct: 412 PLVFAGTVGVMPREHNGQNLFEKKAEPGDLIVMMGGRVGKDGIHGATFSSEALDPNSPVT 471
Query: 275 AGSSVQIGEPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVDLA 332
A VQIG+PI QKK ++VL+ +ARD GLY +ITD GAGG S +V EMA GC V+L
Sbjct: 472 A---VQIGDPITQKKFSDVLVKEARDLGLYRSITDNGAGGLSCSVAEMAKECNGCHVELD 528
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
++P+KY G+APWE+W+SE+QERM +AV +K L LC VE T +G+FTG V
Sbjct: 529 RVPLKYPGMAPWEIWISESQERMTLAVSPEKSAELIDLCARRGVEATLIGKFTGTGRCVV 588
Query: 393 RFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPD-LNAALKAVINHHAV 451
+G K ++++ FLH G P++ L +P + P PD L L A+I +
Sbjct: 589 EYGGKTVMDIELAFLHDGLPKKHLVTRQAPVAEPAVG-PLPPCPDQLGDTLAAMIGRRNI 647
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
S E + YDH VQGG VL P G +G V Q A + + K+AV +S AL P
Sbjct: 648 CSTEFVTIQYDHTVQGGHVLGPVQG-KGRV-QSVATLTKVVPGSKRAVGLSQALFPSYAE 705
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDPY A +AID A+R VA G PE A+LDNFC + PE +W L E AR CY+ A
Sbjct: 706 LDPYRMAGAAIDLAIRGLVATGISPESIALLDNFCWCSSDEPERLWQLKEAARGCYDYAK 765
Query: 572 VFKTPFISGKDSFNNEY--LSSEGKRV--SIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
F TPFISGKDS N++ +E RV S+PP+LLIS++GI D+ + D K G
Sbjct: 766 AFGTPFISGKDSMFNDFSGYDAENNRVKISVPPTLLISSIGIHSDVTKAVSLDAKISGDL 825
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKGLVLSCHDL 686
+Y++G + GS E F + VP AA + Y +L I LV S + +
Sbjct: 826 VYVIGTTEEELAGS---EYFAFLGAGGSTVPCLDAAAARVRYLRLSDAIAHELVSSAYPV 882
Query: 687 SEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKE 746
GG+ AL ++ ++G L D LF ET G +V + +++ AFE+
Sbjct: 883 GHGGIGVALAKVAIAG---RLGMDITLPGALRPDIFLFSETLGRFVVTVAPDHKRAFEQA 939
Query: 747 MEGASIYEIGKTCG 760
+ GA +G T G
Sbjct: 940 L-GADALLLGTTGG 952
>gi|42520738|ref|NP_966653.1| phosphoribosylformylglycinamidine synthase II domain protein
[Wolbachia endosymbiont of Drosophila melanogaster]
gi|42410478|gb|AAS14587.1| phosphoribosylformylglycinamidine synthase II domain protein
[Wolbachia endosymbiont of Drosophila melanogaster]
Length = 1032
Score = 462 bits (1189), Expect = e-128, Method: Composition-based stats.
Identities = 307/795 (38%), Positives = 435/795 (54%), Gaps = 54/795 (6%)
Query: 1 MNDEELLALSNER-----RAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
++D+EL +S + L + M+AI++++K R D E E++AQTWSEHC H
Sbjct: 250 VSDQELEKISRDGIDGNGTLGLSLAAMKAIKDYFKKLGRNPYDIELESLAQTWSEHCKHN 309
Query: 56 TFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFD 115
F + ID E K + + YIK+AT +I++ +S F DNAG I FD
Sbjct: 310 IFCSPID--------EIK--------DGLYAHYIKRATREINSDICVSVFSDNAGGIIFD 353
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFGHPDTPA 173
+ Y + K ETHN PSA++PFGGA TGV GV RD++G A P T CF
Sbjct: 354 DDYLIVDKVETHNSPSALDPFGGAMTGVLGVNRDIVGFGKGAEPIMNTYYFCFAKEAKGK 413
Query: 174 ----ENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGI 229
+ L PK I+ VI GV GN GIPT G V++ + + PLV+ G GI
Sbjct: 414 FYRDKERTDEILPPKYIMKEVIHGVNVAGNCSGIPTQLGSVYFDDRFCGKPLVFVGSIGI 473
Query: 230 APRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
PR H P GD I+ +GG+ GRDG+ GATFSS +A +G+ + VQIG+P
Sbjct: 474 IPRNINNAPSHIKGPKNGDKIVIIGGRVGRDGIHGATFSS---EALSGNSPSTIVQIGDP 530
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPW 344
I QKK++ +I ARD LY+AITD GAGG SS++GEM G +VDL+K+ +K G+A W
Sbjct: 531 ITQKKLSNAVIKARDLDLYNAITDNGAGGLSSSIGEMGKD-GFEVDLSKVLLKNDGMAQW 589
Query: 345 ELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF--TGDAVLRVRFGEKEIINL 402
E+W+SE+QERM +AVP + L +++ +DVE+ +G F +G AV++ G I+++
Sbjct: 590 EIWISESQERMTLAVPEENLPMFKQIMKKHDVEVCVIGEFNESGKAVVKCPEGTV-IMDI 648
Query: 403 SCGFLHSGPPQRKLKAAPPKDGKPFI-KYPEYKEPDLNAALKAVINHHAVNSKEDIVRLY 461
FLH G P+ L+ P G P + P L LK +++ + SKE IV Y
Sbjct: 649 ETEFLHDGNPKVHLQTKPWSKGLPALCAGMTTSSPSLAIELKEMLSRPNICSKEFIVVQY 708
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASA 521
DHEVQG +VL+P G +G V +A V +P+ + K V S G +D Y AA A
Sbjct: 709 DHEVQGSSVLKPLQG-KGRVCSEAIVSRPILSSNKGVVK-SQGFGSSYGEIDTYHMAACA 766
Query: 522 IDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGK 581
ID A+RN VAAG + A+LDNFC D PE +W L + A +CY+ A FKTPFISGK
Sbjct: 767 IDTAIRNYVAAGGNINHLALLDNFCWCDAYNPERLWQLKKAAEACYDFATAFKTPFISGK 826
Query: 582 DSFNNEY--LSSEGKRV--SIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFS 637
DS N++ G++V S PPSLLISA+GI+ +I D K G IY++G+
Sbjct: 827 DSMFNDFKGYDENGEKVIISAPPSLLISAIGIIENIENAVSLDVKMPGDLIYVLGETLDE 886
Query: 638 FGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
G S + GI + V K A +LY++ + G++ S + GGL AL +
Sbjct: 887 LGRSEYQLYSGIGNNNVPKVD--AKSARKLYERYNQARKDGIIASAIAPNLGGLVIALAK 944
Query: 698 MCLSG-IGAELKEDFHT--RLGASKIAS---LFGETTGCLLVEIKEENRSAFEKEMEGAS 751
++G +GAE+ ++ + I + +F E+ +LV I +N+ FE+ EGA
Sbjct: 945 SLIAGDLGAEIDLSLVPIGKIQNTDIINKIIMFSESQSRILVTIAPQNQKRFEELFEGAV 1004
Query: 752 IYEIGKTCGKAGLKL 766
IGK K L +
Sbjct: 1005 YSCIGKVTEKKVLNI 1019
>gi|88606986|ref|YP_504834.1| putative phosphoribosylformylglycinamidine synthase II [Anaplasma
phagocytophilum HZ]
gi|88598049|gb|ABD43519.1| putative phosphoribosylformylglycinamidine synthase II [Anaplasma
phagocytophilum HZ]
Length = 1001
Score = 449 bits (1155), Expect = e-124, Method: Composition-based stats.
Identities = 291/797 (36%), Positives = 427/797 (53%), Gaps = 62/797 (7%)
Query: 1 MNDEELLALSN---ERRAALDIY--EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHK 55
++D EL+ +S + R L++ ++AIR +++ R D E ET+AQTWSEHC H
Sbjct: 205 VSDSELMRISKDGIQNRGPLNLSLDALKAIRAYFEKHNRSPNDIELETLAQTWSEHCKHN 264
Query: 56 TFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFD 115
F A ID + L K YIK+AT DI++P +S+F DNAG I FD
Sbjct: 265 IFSASIDEIASGL----------------YKHYIKRATTDINSPICVSTFSDNAGAIVFD 308
Query: 116 EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFG----HP 169
+ + V K ETHN PSA++PFGGA TG+ GV RD++G + A+P CF P
Sbjct: 309 DDFLVVDKVETHNSPSALDPFGGAETGILGVNRDIIGFGMGAKPIMNAYYFCFAESLEQP 368
Query: 170 DTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGI 229
+ + L P +I+ GVI GV GN GIPT G +++H + PLV+ G GI
Sbjct: 369 LYRDKECKESVLAPTQIMDGVILGVNTGGNCSGIPTAIGSMYFHNRFCGKPLVFVGSTGI 428
Query: 230 APRG-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
PR H GD+I+ +GG+ GRDG+ GATFSS + + G + VQ+G P
Sbjct: 429 IPRHIGEKPAHIKTVKNGDYIVVIGGRVGRDGIHGATFSSHALKENVG---CTVVQVGSP 485
Query: 285 IIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAP 343
I QKK+++ ++ +ARD+GLY+AITD GAGG SS+VGEM G VDL K+P+K + P
Sbjct: 486 ITQKKLSDAIVKEARDRGLYNAITDNGAGGLSSSVGEMGEK-GFIVDLEKVPLKTDKIMP 544
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF--TGDAVLRVRFGEKEIIN 401
WE+W+SE+QERM +AV ++ AL++L +DVE+ +G F TG AV VR I++
Sbjct: 545 WEIWVSESQERMTLAVSPEQYPALEELMLKHDVEIRVIGEFNNTGKAV--VRHNGTVIMD 602
Query: 402 LSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLY 461
+ FLH+G P L K +I + + L ++ + S+E +V Y
Sbjct: 603 IDTDFLHNGNPALTLHTE--KWQPAYIHTTVTHDVSIEDDLLNMMGRKNICSREFLVSQY 660
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASA 521
DHEVQG + ++P G +G + DA V++P+ + + V + +DPY AA A
Sbjct: 661 DHEVQGSSAIKPLQG-KGRICGDAVVLRPVLSS-TRGVVKAQGFGCVYAEIDPYNMAACA 718
Query: 522 IDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGK 581
ID A+RN ++ G + E A++DNFC D P+ +W L + A++CY+ A F TPFISGK
Sbjct: 719 IDTAIRNHISVGGNIEHMALIDNFCWCDATNPKRLWQLKQAAKACYDYATAFGTPFISGK 778
Query: 582 DSFNNEYLSSEGKRVSIP----PSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFS 637
DS N++ +G SI PSLL+S +GI+ D+ K S IY++G
Sbjct: 779 DSMFNDFHGYDGSGTSIHISALPSLLVSTLGIIEDVSNAITQHVKGP-SLIYVLGTTYNE 837
Query: 638 FGGSVFAELFGIPSGESAAVPPFKKEAAE-LYKKLHSNIMKGLVLSCHDLSEGGLAAALY 696
G S + +L+ E+ VP E A LYK+ H M+ ++ S GGLA +L
Sbjct: 838 LGMSEY-QLYSGMGNEN--VPSVNAENAMLLYKRFHQASMRKVIASAIAPGLGGLATSLI 894
Query: 697 EMCLSG-IGAE------LKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
+ + G +GAE + D +K LF E+ ++ + EN+ FE
Sbjct: 895 KSLIGGHMGAEIDLSAVITSDVPQNDMWAKTV-LFSESQSRIIATVSVENQHEFESLFAD 953
Query: 750 ASIYEIGKTCGKAGLKL 766
IG+ + LK+
Sbjct: 954 VPYALIGRVIPEYVLKI 970
>gi|149918900|ref|ZP_01907386.1| Phosphoribosylformylglycinamidine synthase II [Plesiocystis
pacifica SIR-1]
gi|149820274|gb|EDM79691.1| Phosphoribosylformylglycinamidine synthase II [Plesiocystis
pacifica SIR-1]
Length = 1010
Score = 447 bits (1150), Expect = e-123, Method: Composition-based stats.
Identities = 294/806 (36%), Positives = 421/806 (52%), Gaps = 52/806 (6%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
+D L +S E AL + EM+AI ++ R TDAE E +AQTWSEHC HK F + I
Sbjct: 184 DDATLERISKEGMLALTLAEMQAIAAHFRGLGRDPTDAELECLAQTWSEHCKHKIFASPI 243
Query: 62 DI-----DGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDE 116
D T + ++Y ++ + D +++S F DNAG++ F E
Sbjct: 244 RYVDPQGDETLIERGLFRSYVRAATEAVADARKQSGADPEGEDFLVSVFHDNAGVVRFTE 303
Query: 117 KYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDV--LCFGHPDTPAE 174
+ +K ETHN PSA++P+GGA TG+ GV RD G +++V CFG P P
Sbjct: 304 ADHLVYKVETHNSPSALDPYGGAMTGIVGVNRDSFGTGLGADLLSNVWGYCFGDPRGPLR 363
Query: 175 N---VPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGI-- 229
+ +P G +HP+RI GV GV D GN+ GIP G + YA PLVYCG
Sbjct: 364 DRSGLPPGLMHPRRIRDGVHHGVIDGGNQSGIPYSRGFELFDGRYAGKPLVYCGTVAAMP 423
Query: 230 ----------APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
APR + GD ++ +GG+ G+DG+ GATFSS+ +D S+ +V
Sbjct: 424 VTVPGPPPERAPRPTEDKPIAVGDRVVMVGGRIGKDGIHGATFSSVELDESS---PVQAV 480
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASAL-GCDVDLAKIPVKY 338
QIG+PI QK + + L +ARD+GLYS +TD GAGG SS+VGEMA A G +DLAK P+KY
Sbjct: 481 QIGDPITQKMMWDFLSEARDRGLYSGMTDNGAGGLSSSVGEMAEATNGARIDLAKAPLKY 540
Query: 339 QGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKE 398
GLAPWE+ +SEAQERM +AVP +L+A +L +VE + LG FT D RV +G E
Sbjct: 541 PGLAPWEILISEAQERMTVAVPPAQLDAFLELAARREVEASVLGEFTDDGRFRVDYGALE 600
Query: 399 IINLSCGFLHSGPPQRKLKA----APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSK 454
+ +LS F+H G P L+A A + + D AAL ++ +++
Sbjct: 601 VCDLSLEFMHDGVPLPTLEARWSPAQARVVDAGAAEAALAQLDCGAALLDLLARPNLSAN 660
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
+D R YDHEV+G +V++P G EG+VP A ++ + + V + ++P +D
Sbjct: 661 DDRARSYDHEVKGLSVIKPLLGVEGDVPSTATAMR-VRHGRDEGVILGEGIHPWLSDIDT 719
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP----NRPETMWALIEMARSC---Y 567
A A + +DE VR + AGA ++ A LDNFC DP P+ L ++ R C Y
Sbjct: 720 EAMARACVDEGVRRVLCAGARLDRIAALDNFCWPDPIQSAKTPDGHHKLAQLVRCCQGLY 779
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ L + P ISGKDS N+ G ++SIPP+LL+S MG PD+G + + G
Sbjct: 780 DACLAYGVPLISGKDSMKNDAFLG-GVKISIPPTLLVSVMGQTPDVGACLDLEPRAAGDR 838
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL------YKKLHSNIMKGLVL 681
+YL+G G S EL + + +PP +L Y GL+
Sbjct: 839 VYLLGATALELGAS---ELERARADAGSPLPPTDLPRTDLEACWARYGAFAGARDAGLIR 895
Query: 682 SCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENR 740
S H + GGLA +L M L SG+G EL+ D G S A LF E+TG +++ E
Sbjct: 896 SAHVCARGGLALSLAHMVLASGLGLELELDTD---GLSAAAQLFAESTGRIVLTCAEAQG 952
Query: 741 SAFEKEMEGASIYEIGKTCGKAGLKL 766
A E + + +G+ L++
Sbjct: 953 EAVEAALGAHGLQRLGRVVEAPTLRV 978
>gi|88607991|ref|YP_506684.1| putative phosphoribosylformylglycinamidine synthase II
[Neorickettsia sennetsu str. Miyayama]
gi|88600160|gb|ABD45628.1| putative phosphoribosylformylglycinamidine synthase II
[Neorickettsia sennetsu str. Miyayama]
Length = 946
Score = 424 bits (1090), Expect = e-116, Method: Composition-based stats.
Identities = 261/656 (39%), Positives = 366/656 (55%), Gaps = 62/656 (9%)
Query: 4 EELLALSNERRAALDIYEMRAIREFYKTE--KRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
EEL + + + L ++ I E+++ + + D E ETIAQTWSEHC H I
Sbjct: 202 EELASFNCQNALNLSDIQLSKIVEYFRLQEGRSYVRDIELETIAQTWSEHCKHNIMSYPI 261
Query: 62 DIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI--DAP--WVLSSFVDNAGIIEFDEK 117
D L E I + YIKK+T+ I + P S F DNAG I FD+
Sbjct: 262 D----DLQE------------GIFRGYIKKSTETIIRNNPNHICASVFTDNAGAIWFDKD 305
Query: 118 YEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG--VSARPFAVTDVLCFGHPDTPAEN 175
Y + K ETHN PSA+EPFGGA TG+ GV RD++G ++A+P A C PDT ++
Sbjct: 306 YLICVKVETHNSPSALEPFGGAMTGILGVNRDILGFGLAAKPIANYYAFCVEDPDTENQD 365
Query: 176 V------PKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGI 229
+ K L + I+ G+I GV GN GIPT G +++ A+ + PLV+ GCAGI
Sbjct: 366 LYHDSHKTKPKLDSRTILKGIIRGVNAGGNCSGIPTPQGALYFSSAFRAKPLVFVGCAGI 425
Query: 230 AP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
P + P GD I+ GG+TGRDG+ GATFSS + S +V G+ VQ+G+P
Sbjct: 426 IPAKIAEKESWVKAPRDGDLIVIAGGRTGRDGIHGATFSSTGITDS--NVKGTEVQLGDP 483
Query: 285 IIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAP 343
QKK+++ +I + RD L +AITD GAGG SS+VGEM G V L K+ +K GLAP
Sbjct: 484 FTQKKLSDAIIREVRDADLCNAITDNGAGGLSSSVGEMGKN-GFVVHLEKVLLKTIGLAP 542
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
WE+W+SE+QERM A+P +KLEA ++ + VE +G F + F K + +LS
Sbjct: 543 WEIWISESQERMTFAIPREKLEAFGRIMTKHGVEFAVIGEFNRSGRGLITFEGKTVFDLS 602
Query: 404 CGFLHSGPPQRKLKAAPPKD--GKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLY 461
FLH G P L+ P++ G+P + + ++L+ I V S++ I Y
Sbjct: 603 LCFLHDGNPTIHLQTKKPREMRGQPHVSF---------SSLEEAIRDKNVCSRKFIAEQY 653
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN--ALNPRQGLLDPYAAAA 519
DHEVQG ++L+P G + + D IKP+ +K + S A+ R DPY
Sbjct: 654 DHEVQGTSILKPLQG-KNEIFSDVTAIKPL-YNSRKCIGQSQDLAIITR----DPYLDTC 707
Query: 520 SAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFIS 579
S+I++AVRN V G +P+K A+LDNFC D N PE +W L E R+C++T++ TPFIS
Sbjct: 708 SSIEKAVRNLVTIGVNPQKIALLDNFCWSDSNDPEKLWLLKEAGRACHDTSIALGTPFIS 767
Query: 580 GKDSFNNE---YLSSEGK-RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
GKDS N+ Y +S K +VS PSLLI+A+GI+ D + D K IYL+
Sbjct: 768 GKDSMFNDFSGYTTSGAKVKVSNIPSLLITAVGIIDDYEDIVSLDAKYPEDLIYLI 823
>gi|52550037|gb|AAU83886.1| phosphoribosylformylglycinamidine synthase II [uncultured archaeon
GZfos34H9]
Length = 772
Score = 409 bits (1050), Expect = e-112, Method: Composition-based stats.
Identities = 275/781 (35%), Positives = 411/781 (52%), Gaps = 80/781 (10%)
Query: 3 DEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKID 62
D++L +S +L+I EMR I+ +++ ++R TD E ++IAQ WSEHC +K+ K
Sbjct: 11 DDDLKRISELMGLSLNIEEMRTIKRYFQLKRRAPTDVELQSIAQAWSEHCCYKSSK---- 66
Query: 63 IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSF 122
I++ YI IDAP + + ++AG++EFD +
Sbjct: 67 --------------------KILQKYIF----GIDAPQSILAVKEDAGVVEFDADHAYVL 102
Query: 123 KAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLH 182
E+HNHPSAIEP+GGA TG+GG++RDV+ + A+P A+ D L FG D E +P H
Sbjct: 103 AFESHNHPSAIEPYGGAATGIGGIVRDVICMGAQPIALIDPLFFGPLDYSYEKLPAEVKH 162
Query: 183 PKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPSA 241
PK + GV+ G+ DYGN++GIPT G V++ + Y N +V GC GI + R+
Sbjct: 163 PKFLFDGVVAGISDYGNRIGIPTCAGMVYFDDGYVGNCVVNVGCVGIMKKSDLSRSIARE 222
Query: 242 GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA-GSSVQIGEPIIQKKVAEVLIDARDQ 300
G+ ++ +GGKTGRDG+ G TF+S+ + TG+ S+VQ+G+PI ++ + ++++ D+
Sbjct: 223 GEVLVLVGGKTGRDGIHGVTFASVEL---TGEEEFRSAVQVGDPITKEPLMHAILESNDK 279
Query: 301 GLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPVKYQGLAPWELWLSEAQERMVIA 358
L S + D G GG S AV EM A GC ++ L ++ +K +GL+ WE+W+SE+QER +I
Sbjct: 280 KLISGMKDLGGGGLSCAVSEMCHAGGCSAEIHLDRVKLKEEGLSAWEIWVSESQERFLIG 339
Query: 359 VPNDKLEALQKLCDANDVELTNLGRF---------TGDAVLRVRFGEKEIINLSCGFLHS 409
P ++ L + + DV+ LG+ L++ + + I L FL S
Sbjct: 340 TPEANVDELLAIFNKWDVDAVILGQTFKTLSSEEKASPKKLKINYRGENIFELDTDFLVS 399
Query: 410 GPP-QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGG 468
P +R +K + +P + P+ D N LK ++ + S+E ++R YDHEV+
Sbjct: 400 CPLYERTMKIKARDEAEPLMGAPD----DYNVILKQLLAAPNIASREGVIRQYDHEVRAS 455
Query: 469 TVLRPYDGPEGNVPQ-DAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVR 527
TV++P G G DAAVIKP+E E +AI++ LNP ++P+ AASAIDE R
Sbjct: 456 TVIKPMQGIIGKETHGDAAVIKPLE-ESYMGLAITSDLNPSYCKINPFWGAASAIDEVCR 514
Query: 528 NAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNE 587
N A GA P A NF G+P +P+ M E + A PF+SG S NE
Sbjct: 515 NLTAVGAVPHSFADCLNF--GNPEKPDRMGDFYECCHGLGHMASSLGVPFVSGNVSLYNE 572
Query: 588 YLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELF 647
S SIPP+ I +G+ DI D K+ G+ +YL+G + GGS + +L
Sbjct: 573 ---SAAMNESIPPTPAILGIGVCEDIRECVTVDLKEAGNLLYLIGDTKKELGGSEYYKLR 629
Query: 648 GIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG----- 702
G+ G P K L + GLV SCHD+SEGGLA A+ EM + G
Sbjct: 630 GVEGGIVPRTDP--KVLKRSMDALRDTMKAGLVASCHDISEGGLAVAVCEMSMGGDSGVY 687
Query: 703 --IGA---ELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM--EGASIYEI 755
IGA EL+ D+ LF E+ +VE++ FE M G I E+
Sbjct: 688 IDIGAVNPELRSDY----------KLFSESNTRWVVEVQRAVAGRFEALMTTRGICIIEV 737
Query: 756 G 756
G
Sbjct: 738 G 738
>gi|11499524|ref|NP_070765.1| phosphoribosylformylglycinamidine synthase subunit II
[Archaeoglobus fulgidus DSM 4304]
gi|14916644|sp|O28339|PURL_ARCFU Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|2648599|gb|AAB89311.1| phosphoribosylformylglycinamidine synthase II (purL) [Archaeoglobus
fulgidus DSM 4304]
Length = 765
Score = 406 bits (1043), Expect = e-111, Method: Composition-based stats.
Identities = 266/749 (35%), Positives = 407/749 (54%), Gaps = 68/749 (9%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
++EEL +S E AL + EM+ I+++++ + R D E +++AQ WSEHC +K+ K
Sbjct: 20 SEEELAKISEEMGLALSVDEMKRIQDYFRQKGRNPYDIELQSLAQAWSEHCCYKSSK--- 76
Query: 62 DIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVS 121
++ Y+ +A+ A +V+S+ ++AG++EFD++Y
Sbjct: 77 ---------------------YYLRQYLLEASK---ADYVISAIEEDAGVVEFDDEYAYV 112
Query: 122 FKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTL 181
E+HNHPSAIEP+GGA TG+GG++RDV+ + A+P A+ D L FG+ DTP E +P+GT
Sbjct: 113 TAFESHNHPSAIEPYGGAATGIGGILRDVLCMGAQPIALIDPLFFGNLDTPYEKLPRGTK 172
Query: 182 HPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKP 239
HP ++ GV+ G++DYGN++GIPTV G V + +Y +N LV GC GI + + H
Sbjct: 173 HPLYLLKGVVAGIRDYGNRVGIPTVAGMVFFDNSYLTNCLVNVGCVGIVRKDRIIHSRAG 232
Query: 240 SAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARD 299
AGD + GGKTGRDG+ G TF+S +D + + A +VQ+G PI+++ + ++ +
Sbjct: 233 GAGDLFVLAGGKTGRDGIHGVTFASAELDEKSEEEARGAVQLGNPIMKEPLIHACLEVVE 292
Query: 300 QGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVI 357
+GL + + D G GG S +GEMA A G +V L K+P+K +G+APWE+W+SE+QERM++
Sbjct: 293 KGLLTGMKDLGGGGLSCVIGEMALAAGFGAEVYLDKVPLKEEGMAPWEIWISESQERMML 352
Query: 358 AVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLK 417
V + ++ + + DV T +G+ + + R+ + +I + F+ SGP +
Sbjct: 353 TVRPEHIDEVLYIFQKWDVPATVVGKVIPEKITRIYYKGYKIYEMDTEFVTSGPEYCR-- 410
Query: 418 AAPPKDGKPFIKYPEYKEP--DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYD 475
P KP + E EP D +++H KE IVR YDHEV+ TVL+P
Sbjct: 411 --PYVARKPEKELHEEVEPPADYVKTFMKMLSHPNAAFKEWIVRQYDHEVRASTVLKPLQ 468
Query: 476 GPEG-NVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGA 534
G DAAVIKP T + +AI+ +NP +DPY AAS+ DE VRN VA A
Sbjct: 469 GKMNFETHGDAAVIKP--TRSFRGLAITADVNPWMCKVDPYWGAASSFDEMVRNLVAVNA 526
Query: 535 DPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGK 594
P NF G+P +PE M +E ++ A P +SG SF NE +
Sbjct: 527 VPHSFNDCLNF--GNPEKPERMGEFVEAVKALGWMAKGVGVPCVSGNVSFYNE---TPYG 581
Query: 595 RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFG-----I 649
V+ PSLL +GIV D+ + S+FK G A+ LVG+ FGGS+++ + G +
Sbjct: 582 AVAPTPSLL--GVGIVEDVRKAITSEFKGRG-AVILVGETHNEFGGSLYSAVMGQRCHKV 638
Query: 650 PSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELK 708
P + + E ++K V +CHD+S GGLA + EM G+G E
Sbjct: 639 PRTSPERLKTYSDAMLESFRKFE-------VKACHDVSMGGLAVCIAEMSFGRGLGFEAA 691
Query: 709 EDFHTRLGASKIASLFGETTGCLLVEIKE 737
+ LF E+ +VE+ E
Sbjct: 692 REL-------SFVELFSESNTRWVVEVPE 713
>gi|52549856|gb|AAU83705.1| phosphoribosylformylglycinamidine synthase II [uncultured archaeon
GZfos33E1]
Length = 772
Score = 404 bits (1037), Expect = e-110, Method: Composition-based stats.
Identities = 275/781 (35%), Positives = 413/781 (52%), Gaps = 80/781 (10%)
Query: 3 DEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKID 62
D++L +S +L+I EM AI+ ++ ++R TD E ++IAQ WSEHC +K+ K
Sbjct: 11 DDDLKRISELMGLSLNIEEMHAIKRYFLLKRRAPTDVELQSIAQAWSEHCCYKSSK---- 66
Query: 63 IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSF 122
I++ YI IDAP + + ++AG++EFDE++
Sbjct: 67 --------------------KILQKYIF----GIDAPQSILAVKEDAGVVEFDEEHAYVV 102
Query: 123 KAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLH 182
E+HNHPSAIEP+GGA TG+GG++RDV+ + A+P A+ D L FG D E +P H
Sbjct: 103 AFESHNHPSAIEPYGGAATGIGGIVRDVICMGAQPIALIDPLFFGPLDYSYEKLPAEVKH 162
Query: 183 PKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPSA 241
PK + GV+ G+ DYGN++GIPT G V++ + Y N +V GC GI + R+
Sbjct: 163 PKFLFDGVVAGISDYGNRIGIPTCAGMVYFDDGYVGNCVVNVGCVGIMKKSDLSRSIARE 222
Query: 242 GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA-GSSVQIGEPIIQKKVAEVLIDARDQ 300
G+ ++ +GGKTGRDG+ G TF+S+ + TG+ S+VQ+G+PI ++ + ++++ ++
Sbjct: 223 GEVLVLVGGKTGRDGIHGVTFASVEL---TGEEEFRSAVQVGDPITKEPLMHAILESNEK 279
Query: 301 GLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPVKYQGLAPWELWLSEAQERMVIA 358
L S + D G GG S AV EM A GC ++ L ++ +K +GL+ WE+W+SE+QER +I
Sbjct: 280 KLISGMKDLGGGGLSCAVSEMCHAGGCGAEIHLDRVKLKEEGLSAWEIWVSESQERFLIG 339
Query: 359 VPNDKLEALQKLCDANDVELTNLGRF---------TGDAVLRVRFGEKEIINLSCGFLHS 409
P ++ L + + DV+ LG+ L++ + + I L FL S
Sbjct: 340 TPEANVDELLAIFNKWDVDAVILGQTFKNLSPEEKASPKKLKIIYRGENIFELDTDFLVS 399
Query: 410 GPP-QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGG 468
P +R ++ + +P + P+ D N LK ++ + S+E ++R YDHEV+
Sbjct: 400 CPLYERTMEIKARDEVEPLMGAPD----DYNGTLKQLLAAPNIASREGVIRQYDHEVRAS 455
Query: 469 TVLRPYDGPEGNVPQ-DAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVR 527
TV++P G G DAAVIKP+E E +AI++ +NP ++P+ AASAIDE R
Sbjct: 456 TVIKPMQGIIGKETHGDAAVIKPLE-ESYMGLAITSDVNPSYCNINPFWGAASAIDEVCR 514
Query: 528 NAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNE 587
N A GA P+ A NF G+P +P+ M E R + A PF+SG S NE
Sbjct: 515 NLTAVGAVPQSFADCLNF--GNPEKPDRMGDFYECCRGLGHMASSLGVPFVSGNVSLYNE 572
Query: 588 YLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELF 647
S SIPP+ I +G+ DI D K+ G+ +YL+G + FGGS + +L
Sbjct: 573 ---SAAMNESIPPTPAILGIGVCEDIRECVTVDLKEVGNLLYLIGDTKKEFGGSEYYKLR 629
Query: 648 GIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG----- 702
G+ G P K L + GLV SCHD+SEGGLA A+ EM + G
Sbjct: 630 GVEGGLVPRTDP--KVLKRSMDALLDTMKAGLVASCHDISEGGLAVAVCEMSMGGDSGVY 687
Query: 703 --IGA---ELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM--EGASIYEI 755
IGA EL+ D+ LF E+ +VE+ FE M I EI
Sbjct: 688 IDIGAVNPELRSDY----------KLFSESNTRWVVEVPRAELGRFEALMATHDVCIIEI 737
Query: 756 G 756
G
Sbjct: 738 G 738
>gi|48478277|ref|YP_023983.1| phosphoribosylformylglycinamidine synthase subunit II [Picrophilus
torridus DSM 9790]
gi|56749598|sp|Q6KZR2|PURL_PICTO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|48430925|gb|AAT43790.1| phosphoribosylformylglycinamidine synthase [Picrophilus torridus
DSM 9790]
Length = 741
Score = 399 bits (1026), Expect = e-109, Method: Composition-based stats.
Identities = 244/750 (32%), Positives = 407/750 (54%), Gaps = 68/750 (9%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
ND +L+ S AL EM I++++ KR +D E + IAQ+WSEH +K+
Sbjct: 9 NDLDLIGKS----LALSHDEMLLIKKYFTEIKRNPSDVELQAIAQSWSEHSCYKS----- 59
Query: 62 DIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVS 121
K Y+KK ++ + + D+AG+++F++ Y
Sbjct: 60 -----------------------SKFYLKKYLSNLRNERTILAMEDDAGVVKFNDDYVYV 96
Query: 122 FKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTL 181
K E+HNHPSA+EP+GGA TGVGG+IRDV+ + A+P A+ D L FG PD + G L
Sbjct: 97 VKMESHNHPSAVEPYGGAATGVGGIIRDVLCMGAQPVALVDSLYFGDPDNKS-----GFL 151
Query: 182 HPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTK-P 239
+ II+GV+ G++DYGN++GIP V G +++HE Y ++P+V GC GI+ + K R++
Sbjct: 152 SERFIINGVVSGIRDYGNRLGIPNVAGSIYFHEGYNTSPIVNAGCIGISRKDKIVRSRVQ 211
Query: 240 SAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARD 299
A D +I GG+TGRDG+ G F+S V+D G+ ++VQ+G PI+++ + +++ D
Sbjct: 212 KARDILILCGGRTGRDGIHGVNFASRVLDLKNGE-NRNAVQLGNPIVEEPLIHAILELND 270
Query: 300 QGLYSAITDCGAGGYSSAVGEM--ASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVI 357
GL + + D G GG SSAV EM A LG ++L + +K + PWE+W+SE+QERM+I
Sbjct: 271 LGLITGMKDLGGGGLSSAVTEMLYAGNLGGTINLDSVLLKDDNMLPWEIWISESQERMLI 330
Query: 358 AVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLK 417
+ L ++ + D ++E + +GR L + + +++ +L F+ P ++
Sbjct: 331 SSDERNLPQIKDVLDKWNIEFSVIGRAEEKKNLEIYYKNEKVFDLPLEFISKTPVYQR-- 388
Query: 418 AAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDG- 476
P K + K +++ D+N ++ ++I+ V S+ ++R YDH V+G T++RP G
Sbjct: 389 --PYKKPRNRCKSEPFRDDDINKSIISLISSINVCSRAPVIRQYDHTVRGATIVRPLTGL 446
Query: 477 PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADP 536
P DAAVIKP++ + +A+++ P +DPY A ++ EA +N + GA+P
Sbjct: 447 PNNETHSDAAVIKPVD-DSFAGIAVTSGSKPMLCTIDPYGGALESLIEAYKNIIVTGAEP 505
Query: 537 EKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRV 596
+ AI+D+ G+P ETM++ +E ++ + L FK +SG SF N+ +S
Sbjct: 506 D--AIVDSLNFGNPENEETMYSFVETLKAIRDFTLKFKLQLVSGNVSFYNKNVS------ 557
Query: 597 SIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAA 656
I P+ I GI+ D+ + ++FK + S IYL+G S G+V+++L I +
Sbjct: 558 DIMPTPNIMMTGIIDDVRKAITTEFKNKNSLIYLIGSINGSLAGTVYSKLKDIKCYDYHN 617
Query: 657 VPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHT 713
+ +Y + N K +L+ HD+S+GG+ AAL EM G LK+
Sbjct: 618 SN--INDLCNVYNIIKEN--KEKILAAHDVSDGGIIAALIEMSFGKNIGFNVNLKD---- 669
Query: 714 RLGASKIASLFGETTGCLLVEIKEENRSAF 743
+ + LF E +++E+ E+ F
Sbjct: 670 -IKMNLENKLFSEHGTAIVIEVPLESEIVF 698
>gi|16082093|ref|NP_394526.1| phosphoribosylformylglycinamidine synthase subunit II [Thermoplasma
acidophilum DSM 1728]
gi|14916664|sp|Q9HJA4|PURL_THEAC Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|10640380|emb|CAC12194.1| phosphoribosylformylglycinamidine synthase related protein
[Thermoplasma acidophilum]
Length = 759
Score = 390 bits (1003), Expect = e-106, Method: Composition-based stats.
Identities = 253/769 (32%), Positives = 411/769 (53%), Gaps = 63/769 (8%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKI 61
+D L A+S AL + EM+A+R +++ R DAE +AQ+WSEHC +K+
Sbjct: 12 DDARLKAISKRLGLALSLDEMKAVRSYFERLGRDPIDAEIHAVAQSWSEHCSYKS----- 66
Query: 62 DIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVS 121
K Y+KK + + + + D+AG+++FD +Y
Sbjct: 67 -----------------------SKYYLKKYLGSLKTDYTILAMEDDAGVVDFDGEYAYV 103
Query: 122 FKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTL 181
K E+HNHPSA+EP+GGA TG+GG++RDV+ + A+P A+ D L G D ++ +G L
Sbjct: 104 LKMESHNHPSAVEPYGGAATGIGGIVRDVLCMGAQPVALIDSLFLG--DVSSDRY-EGLL 160
Query: 182 HPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKP- 239
P+ I GV+ G++DYGN++GIP V G +++ + Y SNPLV GC GI R + R+K
Sbjct: 161 SPRYIFGGVVGGIRDYGNRIGIPNVAGSLYFDKLYNSNPLVNAGCVGIVRRDRIVRSKSY 220
Query: 240 SAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS---VQIGEPIIQKKVAEVLID 296
GD ++ +GGKTGRDG+ G F+S + G V SS +Q+G PI+++ + + +++
Sbjct: 221 KPGDVLVLMGGKTGRDGIHGVNFASTTL----GKVTKSSRLAIQLGNPIVEQPMIKAVLE 276
Query: 297 ARDQGLYSAITDCGAGGYSSAVGEM--ASALGCDVDLAKIPVKYQGLAPWELWLSEAQER 354
A D GL A+ D G GG SSA EM A G ++ L I +K ++ WE+W+SE+QER
Sbjct: 277 ANDAGLIRAMKDLGGGGLSSAATEMVYAGGFGAEITLDDIKLKESNMSGWEIWISESQER 336
Query: 355 MVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP-Q 413
M++ + +E ++++ + +++ + +G+ T D +RV + +++II++ FL P Q
Sbjct: 337 MLMECYPEDVEKIRQIAEKWNLDFSVIGQVTADRRIRVYYKKRKIIDMDIEFLDDSPVYQ 396
Query: 414 RKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRP 473
R + K+ + + P+ E DLN+ ++ + ++ ++VR YDH V+G T++ P
Sbjct: 397 RPYRI---KEVEKSVTVPQEPE-DLNSFVRDFMARLNTCARFNVVRQYDHTVRGSTIVTP 452
Query: 474 YDG-PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAA 532
+ G P DA VIKP+E + + +++ P +DPYA + EA +N ++
Sbjct: 453 FVGRPNKETHADATVIKPLENS-MRGLVLTSGSRPNMVSVDPYAGTLLTLAEAYKNILST 511
Query: 533 GADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSE 592
G P +++D G+P R E M +E R+ + P ++G SF NEY
Sbjct: 512 GGRPH--SVVDALNFGNPEREEIMGQFVESVRAIGDFCRKMGLPVVAGNVSFYNEY---- 565
Query: 593 GKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSG 652
++ I P+ I +G++ D+ R + K G+AIYL+G+P + GS ++ + G G
Sbjct: 566 -RKTDIMPTPTIMMVGLIDDVRRSRTTYMKGSGNAIYLIGEPCDNLTGSEYSRMHGYTDG 624
Query: 653 ESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDF 711
A P E + L S ++LS HD+S GGL AAL EM SGIG + D
Sbjct: 625 FLPA--PDLDELTRIRDFLSSK--ADMILSSHDVSSGGLFAALSEMSFGSGIGFHV--DI 678
Query: 712 HTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCG 760
A LF E L++EI ++ F G +I +G+T G
Sbjct: 679 SNVSAARPTVKLFSECGNGLVLEIAKDKEEQFVDGSNGLAIKRLGETGG 727
>gi|13541352|ref|NP_111040.1| phosphoribosylformylglycinamidine synthase subunit II [Thermoplasma
volcanium GSS1]
gi|20139593|sp|Q97BD5|PURL_THEVO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|14324736|dbj|BAB59663.1| phosphoribosylformylglycinamide synthase large subunit
[Thermoplasma volcanium GSS1]
Length = 759
Score = 388 bits (997), Expect = e-106, Method: Composition-based stats.
Identities = 252/767 (32%), Positives = 406/767 (52%), Gaps = 57/767 (7%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAK 60
MND++L+ +S +L + EM+A+R+++ E R DAE IAQ+WSEHC +K+ K
Sbjct: 11 MNDDDLINMSKRHGLSLSLDEMKAVRDYFIKEGRDPIDAEIHAIAQSWSEHCSYKSSK-- 68
Query: 61 IDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEV 120
Y+KK ++ + + + D+AG++EFD+ Y
Sbjct: 69 --------------------------FYLKKYLTNLKTDYTILAMEDDAGVVEFDKDYAY 102
Query: 121 SFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGT 180
K E+HNHPSA+EP+GGA TG+GG++RDV+ + A+P A+ D L G D ++
Sbjct: 103 VLKMESHNHPSAVEPYGGAATGIGGIVRDVVCMGAQPIALVDSLFMG--DVASQKY-DAL 159
Query: 181 LHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKP 239
L P+ I GV+ G++DYGN++G+P V G V++ ++Y SNPLV GC GI + + R+K
Sbjct: 160 LSPRYIFQGVVGGIRDYGNRIGVPNVAGSVYFDQSYNSNPLVNAGCIGIVRKDRIVRSKS 219
Query: 240 -SAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDAR 298
AGD ++ +GGKTGRDG+ G F+S + + +++Q+G PI++ + +++A
Sbjct: 220 YKAGDKLLLVGGKTGRDGIHGVNFASATL-TRISKSSRNAIQLGNPIVEHPMMRAVLEAN 278
Query: 299 DQGLYSAITDCGAGGYSSAVGEM--ASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMV 356
+ G+ A+ D G GG SSA EM A G ++ L I +K ++ WE+W+SE+QERM+
Sbjct: 279 ELGIIKAMKDLGGGGLSSAATEMVFAGGFGAEISLDDIKLKDTDMSGWEIWISESQERML 338
Query: 357 IAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP-QRK 415
+ V + +E ++++ + ++ + LG + VR+ K+II++ FL P QR
Sbjct: 339 VEVLPEDVEKMKEIAEKWSLDFSILGTVVEGKKITVRYKNKKIIDMDIEFLDKAPVYQRP 398
Query: 416 LKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYD 475
+ K+ + + P E DLN ++ +++ ++VR YDH V+G T++ P+
Sbjct: 399 FER---KNIEKKVSIPSEPE-DLNDFALNFVSRLNNSARFNVVRQYDHTVRGSTIVGPFS 454
Query: 476 G-PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGA 534
G P DA VIKP+E + + + I++ P +DPY + EAVRN V+ G
Sbjct: 455 GRPNLETHSDATVIKPLE-DSMRGLLITSGSRPNFVSIDPYNGTLETLSEAVRNIVSTGG 513
Query: 535 DPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGK 594
P +++D G+P R + M +E R+ + F P ++G SF NE+ + +
Sbjct: 514 KP--NSVVDALNFGNPERQDIMGQFVESVRAIGDFCRKFSLPVVAGNVSFYNEFRNKD-- 569
Query: 595 RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGES 654
I P+ I +GI+ D+ + + FKK S IYLVG P + GS +A + I G
Sbjct: 570 ---IMPTPTIMMVGIIDDVTKARTTYFKKNKSQIYLVGTPCDNLSGSEYARMNNIFDGFL 626
Query: 655 AAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHT 713
A P + E+ K +LS HD+S+GGL AL EM SGIG + D
Sbjct: 627 PA-PNLSELQLEIEK---IGKFSPYILSAHDVSDGGLFMALAEMSFGSGIGFNI--DLGN 680
Query: 714 RLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGKTCG 760
+ LF E +++EI + F E + I IG+T G
Sbjct: 681 VSASRSSVKLFSECGNQIVLEIDPIHEEEFTAEFKDLKIVRIGETGG 727
>gi|116747880|ref|YP_844567.1| Phosphoribosylformylglycinamidine synthase [Syntrophobacter
fumaroxidans MPOB]
gi|116696944|gb|ABK16132.1| Phosphoribosylformylglycinamidine synthase [Syntrophobacter
fumaroxidans MPOB]
Length = 1009
Score = 373 bits (958), Expect = e-101, Method: Composition-based stats.
Identities = 277/812 (34%), Positives = 407/812 (50%), Gaps = 87/812 (10%)
Query: 4 EELLALSNERRAALDIYEMRAIREFYKTEKRP-------------CTDAEFETIAQTWSE 50
E+L+ LS+ER AL+ ++ I +++ RP TD E E I+Q S+
Sbjct: 188 EDLMRLSDERNLALNPLDVPVILDYFA---RPEVVRARREMGLGAPTDVELEAISQARSD 244
Query: 51 HCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP--WVLSSFVDN 108
HC H TF+ K + E V+++ KT I+ T I A WV+S DN
Sbjct: 245 HCNHNTFRGKFHYRDLATGERT-------VVDNLFKTCIEAPTLAIQAEKDWVVSVLWDN 297
Query: 109 AGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCF 166
AG+ FD+ ETHN PS +E +GGA TG+ G+ RD+MG AR A C
Sbjct: 298 AGVARFDDNNNYVITGETHNSPSNMEAYGGALTGIVGIYRDIMGTGKGARLTAGLYGYCV 357
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G D P LHP+R++ G++EGVKD GNK G+PT G + +H ++ LV+
Sbjct: 358 GPKDYRGPLRPH--LHPRRLLDGIVEGVKDGGNKHGVPTPFGNLFFHPSFLGKCLVFVAA 415
Query: 227 AGIAPR-----GKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQI 281
GI PR +P GD II GG+ G+DG+ G T SS + ST VQI
Sbjct: 416 LGIMPRLVRGEPSDLKRPDPGDFIIMSGGRVGKDGIHGVTASSEIYSEST---PAGHVQI 472
Query: 282 GEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALG-CDVDLAKIPVKYQG 340
G+P QKK+ + L++ARD+GL S ITD G GG SS+VGE A G V+L K+P+KY+G
Sbjct: 473 GDPYTQKKMHDFLLEARDEGLISFITDNGGGGLSSSVGESARFCGGARVELDKVPLKYEG 532
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
L WE+W+SE+QERM +AV L+ +L ++VE T +G + D L + + K
Sbjct: 533 LDQWEIWVSESQERMTVAVNPRHLDRFMELSRRHEVESTAIGTYGSDGRLHLTYRGKTCA 592
Query: 401 NLSCGFLHSGPPQRKLKA--APPKDGKPFIKYPEYKEP-DLNAALKAVINHHAVNSKEDI 457
L PQ + +A PP + + P EP D L V+ V S+E I
Sbjct: 593 CLDLSLFTEAFPQWEFEADWQPPDNRG--LHEPVLAEPADYGRLLHDVLARPNVCSREWI 650
Query: 458 VRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAA 517
R YDHEVQGG+V++ G + +VP DAAV++P E ++ +A+S ++NP +D Y
Sbjct: 651 QRQYDHEVQGGSVIKLMTGVDRDVPNDAAVLRP-ALESRRGLAVSQSINPTYSAIDTYHM 709
Query: 518 AASAIDEAVRNAVAAGADPEKTAILDNFCLG----DP-NRPETMWALIEMARSCY---NT 569
A+ IDEAVR VA G E+ +DNFC DP + P+ + ++ R+ + +
Sbjct: 710 VAATIDEAVRRLVAVGGRLEEIGGVDNFCWPSVQYDPVSNPDGRYKAAQLVRANWALRDI 769
Query: 570 ALVFKTPFISGKDS-FNNEYLS---SEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEG 625
L F P +SGKDS + + +L E ++S P++ +A +VPDI D K G
Sbjct: 770 CLAFGIPLLSGKDSMYVDGHLGGAYGERHKISGLPTMQFTATTVVPDISDCQTMDVKTAG 829
Query: 626 SAIYLVGKPQFSFGGSVFAELFG-----IPSGESAAVPPFKKEAAELYKKLHSNIMKGLV 680
+Y++G GGS + + FG +P + +V P +Y+ + I +GLV
Sbjct: 830 DLVYVLGWTHDELGGSEYYDCFGYLGRNVPELDPESVLP-------VYRVVEKAIREGLV 882
Query: 681 LSCHDLSEGGLAAA---------------LYEMCLSGIGAELKEDFHTRLGASKIASLFG 725
SCH + GGL L ++ ++ GA+ K + G LF
Sbjct: 883 ASCHGIYRGGLGVHAAMAAMAGGLGMRLDLEKVPVAHAGAQAK----SGPGPRDDHILFS 938
Query: 726 ETTGCLLVEIKEENRSAFEKEMEGASIYEIGK 757
E+ G ++ + R AFE G +G+
Sbjct: 939 ESCGRFILTVSPAMRGAFEAMAGGLPCAPVGE 970
>gi|121541624|ref|ZP_01673373.1| Phosphoribosylformylglycinamidine synthase [Candidatus
Desulfococcus oleovorans Hxd3]
gi|121518510|gb|EAX55369.1| Phosphoribosylformylglycinamidine synthase [Candidatus
Desulfococcus oleovorans Hxd3]
Length = 998
Score = 373 bits (958), Expect = e-101, Method: Composition-based stats.
Identities = 273/802 (34%), Positives = 405/802 (50%), Gaps = 60/802 (7%)
Query: 2 NDEELLALSNERRAALDIYEMRAIREFYKTEKRPC----------TDAEFETIAQTWSEH 51
+D L+ +S+ER AL+ ++ IRE++ ++ TD E E I+Q S+H
Sbjct: 185 SDAALMKVSDERNLALNPNDVPVIREYFVRKEVRERRRAVGLSDPTDIEVEYISQARSDH 244
Query: 52 CVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDI--DAPWVLSSFVDNA 109
C H TF + E K ++S+ T I++ T D+ + PWV+S DNA
Sbjct: 245 CNHNTFGGRFYYKDLITGETLK-------IDSLFATCIRQPTLDLQKEKPWVVSVLWDNA 297
Query: 110 GIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS--ARPFAVTDVLCFG 167
G+ FDE + ETHN PS +E +GGA TG+ GV RD MG AR C G
Sbjct: 298 GMARFDEDHCYVITGETHNSPSNMEAYGGAMTGIVGVYRDPMGTGKGARLVMGGYGFCTG 357
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
D + P+ L P+R++ GVIEGVKD GNK GIPT G +++ + Y LV+
Sbjct: 358 RRDYDGDLKPR--LSPRRLLDGVIEGVKDGGNKSGIPTTFGQLYFDDGYMGKCLVFVTAI 415
Query: 228 GI-------APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQ 280
GI P K T+P D I+ GG+ G+DG+ G T SS V T VQ
Sbjct: 416 GILPAYINGEPSDKKTTRPD--DLIVMCGGRVGKDGIHGVTASSEVYSEHT---PAGHVQ 470
Query: 281 IGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA-SALGCDVDLAKIPVKYQ 339
IG+P QKK+ + L+ ARD GL ITD G GG SS+VGE A + GC+V L K+P+KY
Sbjct: 471 IGDPYTQKKMHDFLLCARDAGLIQFITDNGGGGLSSSVGESALYSGGCEVWLEKVPLKYA 530
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEI 399
GL WE+W+SE+QERM +AV + ++ L + VE T +G++T +L + +
Sbjct: 531 GLDQWEIWVSESQERMTVAVAPENIDRFLALSADHAVESTVIGKYTDSGMLHILYDGATC 590
Query: 400 INLSCGFLHSGPPQRKLKAA-PPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIV 458
+ F+ S PQ + +A P + + + PD N L ++ + S+E +
Sbjct: 591 AYIDLDFMASDFPQWEFEAHWTPPEARGLCEPVLGGSPDFNTLLSDMLARPNICSREWVA 650
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
R YDHEVQGG+ ++P G + ++ DAAV +P+ +K +A + AL P +D Y
Sbjct: 651 RQYDHEVQGGSAVKPLVGADRDIASDAAVTRPV-LASEKGIAFAQALLPAYSKIDAYHMT 709
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPN-------RPETMWALIEMARSCY---N 568
+ IDEAVR VA GADP +DNFC PN P+ + ++ RSC +
Sbjct: 710 TAVIDEAVRRLVAVGADPAGIGGVDNFCW--PNIAYNPASNPDGRFKAAQLVRSCLALRD 767
Query: 569 TALVFKTPFISGKDS-FNNEYLS---SEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKE 624
F P +SGKDS + + +L+ E ++VS P++ SA +V D+ + K E
Sbjct: 768 ACNAFGIPLLSGKDSMYVDGHLAGRYGETRKVSALPTMQFSATAVVDDVTACTTLEAKAE 827
Query: 625 GSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSC 683
G +Y+ G + G S + EL G +P + E++ + + + + I +GL S
Sbjct: 828 GDLVYVAGITRNELGASEYYELLGF---TGLTIPRVRFDESSAVCRAVATAIGRGLCASV 884
Query: 684 HDLSEGGLAAALYEMCLSG-IGAELK-EDFHTRLGASKIASLFGETTGCLLVEIKEENRS 741
H + GGL L + + G +G + G S A LF E+ ++ + ENR+
Sbjct: 885 HGVYRGGLGVHLAFVAMGGNLGMTVDLSKIVQEPGLSDHALLFSESPARFVITVAPENRA 944
Query: 742 AFEKEMEGASIYEIGKTCGKAG 763
AFE + A IG GK G
Sbjct: 945 AFEALWQDAPCACIGTVTGKNG 966
>gi|126008840|ref|ZP_01709411.1| hypothetical protein Faci_03000517 [Ferroplasma acidarmanus fer1]
Length = 749
Score = 357 bits (917), Expect = 1e-96, Method: Composition-based stats.
Identities = 235/748 (31%), Positives = 384/748 (51%), Gaps = 71/748 (9%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E+ +R ++ R TD E + IAQ WSEH +K+
Sbjct: 25 EIVMLRNYFTGLGRNPTDIEIQAIAQGWSEHSCYKS------------------------ 60
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
K Y+KK + + + + + D+AG+I FD+ Y K E+HNHPSA+EP+GGA
Sbjct: 61 ----SKLYLKKYFSGLKSDYTILTMEDDAGVISFDKDYAYVVKMESHNHPSAVEPYGGAA 116
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG+IRDV+ + A+P A+ D L FG PD G L + I++ V+ G++DYGN+
Sbjct: 117 TGVGGIIRDVLCMGAQPVALVDSLYFGDPDN-----MDGNLTERFILNRVVAGIRDYGNR 171
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKH--RTKPSA-GDHIISLGGKTGRDGL 257
+GIPTV G H+++ Y PLV GC GI R H R++ S GD +I GG+TG+DG+
Sbjct: 172 VGIPTVAGSTHFNKVYNGMPLVNAGCIGIV-RKDHVVRSRVSVEGDLLIVCGGRTGKDGI 230
Query: 258 RGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSA 317
G F+S V+D + + ++VQ+G PII++ + +++A ++ + + D G GG SSA
Sbjct: 231 HGVNFASKVLDKGSEE-NRNAVQLGNPIIKEPLIHAILEANEERIIDGMKDLGGGGLSSA 289
Query: 318 VGEMASALGCD--VDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND 375
V EM A G ++L K+ +K + PWE+W+SE+QERM +A+ L+ + ++ +
Sbjct: 290 VSEMLFAGGMSGIINLDKVLLKDSHMEPWEIWVSESQERMFLAIKPSNLQKISRIFEKWG 349
Query: 376 VELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE 435
+E + +G + L + F ++I+++ FL GP + P + K + +E
Sbjct: 350 IEYSIIGETVKNENLVINFNGEKILDMKLSFLTGGPMYARSYKKPEMEEKTVLD----RE 405
Query: 436 PD--LNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDG-PEGNVPQDAAVIKPME 492
P+ + LK + N + + S+ +IVR YD V+G T+++P+ G P DA +IKP+E
Sbjct: 406 PENYRDFILKFLSNPN-ICSRFNIVRQYDFTVRGNTIVKPFAGFPNHETHSDATIIKPVE 464
Query: 493 TEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNR 552
E + + +++ P ++PY + E RN +++G P +I+D G+P
Sbjct: 465 -ESYQGLCLTSGSIPEMVGIEPYNGTMHVLSEGYRNILSSGGRPH--SIVDALNFGNPEN 521
Query: 553 PETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPD 612
PETM+ IE + + P +SG SF NE + I P+ + +G + D
Sbjct: 522 PETMYRFIESIHAISDFCKATGLPLVSGNVSFYNE------TDIEILPTPNMLLIGKIED 575
Query: 613 IGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFK-KEAAELYKKL 671
+ R + K G+ IYL G GS ++ + G +P E + K L
Sbjct: 576 VRRAKTVEAKTPGNPIYLAGSIINDLAGSQYSSIMGTV---HTKLPDMDIDELVNINKDL 632
Query: 672 HSNIMKGLVLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETT 728
++ + S HD+S GGL A+ EM GI A++ D H R LF E
Sbjct: 633 SDSM--DYIESMHDISTGGLLMAILEMSFGGPYGIEADI-SDIHGRTN----EKLFSELG 685
Query: 729 GCLLVEIKEENRSAFEKEMEGASIYEIG 756
+L+E+++ + F + ++I +IG
Sbjct: 686 TGILIEVRKSDEKDFLEAFSRSNIRKIG 713
>gi|116873203|ref|YP_849984.1| phosphoribosylformylglycinamidine synthase II [Listeria welshimeri
serovar 6b str. SLCC5334]
gi|116742081|emb|CAK21205.1| purL [Listeria welshimeri serovar 6b str. SLCC5334]
Length = 739
Score = 328 bits (841), Expect = 9e-88, Method: Composition-based stats.
Identities = 236/725 (32%), Positives = 357/725 (49%), Gaps = 88/725 (12%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HSKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELN 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V ++ +Q L D +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVDEIQALFDRYGLEAVVIGKVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPP------KDGKPFIKYPEYKEPDLNAALKAVINHHAVNSK 454
N+ L P + P ++ +PF+ E D+ K ++ + SK
Sbjct: 369 NVPVDALAEDAPVYHKPSTEPARYQAFQEEQPFVPVME----DVVEVWKELLAQPTIASK 424
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
I YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 425 RHIYEQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDP 474
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFK 574
A A+ EA RN V +G P AI D G+P +PE W + + A L
Sbjct: 475 EVGGAIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELD 532
Query: 575 TPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKP 634
TP ISG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+
Sbjct: 533 TPVISGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGET 587
Query: 635 QFSFGGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLA 692
+ + GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG
Sbjct: 588 KAEYNGS---ELQKLQQGKISGRAPELDLTTEKKYQELLLTAIREGLVSSSHDLAEGGFG 644
Query: 693 AALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGAS 751
AL E +G+GA+++ F + LF E+ LV +K EN + F K ME
Sbjct: 645 VALAEATFKAGLGADVEVPF-------ALNQLFSESQSRFLVSVKPENEAVFAKIMEQEK 697
Query: 752 IYEIG 756
+Y +G
Sbjct: 698 VYRLG 702
Score = 62.0 bits (149), Expect = 2e-07, Method: Composition-based stats.
Identities = 68/275 (24%), Positives = 120/275 (43%), Gaps = 35/275 (12%)
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
++P G V R+++ +P A+TD L FG+P+ P I +
Sbjct: 472 LDPEVGGAIAVAEAARNIVCSGGKPLAITDGLNFGNPEKPEIFWE---------IEKAAD 522
Query: 193 GVKDYGNKMGIPTVNGGVH-YHEAYASN--PLVYCGCAGIAPRGKHRTK---PSAGDHII 246
G+ ++ P ++G V Y+E + P G G+ H T ++GD +I
Sbjct: 523 GISAACLELDTPVISGNVSLYNETDGTGIYPTPVIGMVGLVEDLAHITTQDFKNSGD-VI 581
Query: 247 SLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAI 306
L G+T + S + G ++G + ++ + +KK E+L+ A +GL S+
Sbjct: 582 FLIGET-----KAEYNGSELQKLQQGKISGRAPEL-DLTTEKKYQELLLTAIREGLVSSS 635
Query: 307 TDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL 364
D GG+ A+ E + LG DV+ +P L SE+Q R +++V +
Sbjct: 636 HDLAEGGFGVALAEATFKAGLGADVE---VPFALNQL------FSESQSRFLVSVKPENE 686
Query: 365 EALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEI 399
K+ + V LG T D +RV++ E+E+
Sbjct: 687 AVFAKIMEQEKV--YRLGVVTADETIRVKYKEEEV 719
>gi|46907999|ref|YP_014388.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes str. 4b F2365]
gi|67460861|sp|Q71YP9|PURL_LISMF Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|46881269|gb|AAT04565.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes str. 4b F2365]
Length = 739
Score = 327 bits (838), Expect = 2e-87, Method: Composition-based stats.
Identities = 234/721 (32%), Positives = 356/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELN 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEESFVPVMEDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPKVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLTTEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F ++ LF E+ LV +K EN +AF + ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ELNQLFSESQSRFLVSVKPENEAAFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|153198058|ref|ZP_01942208.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes 10403S]
gi|127632221|gb|EBA21910.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes 10403S]
Length = 739
Score = 327 bits (837), Expect = 2e-87, Method: Composition-based stats.
Identities = 235/721 (32%), Positives = 356/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDSCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELH 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEEAFVPVIDDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKASGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL I G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKIQQGKISGRAPELDLVTEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F ++ LF E+ LV +K EN +AF + ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ALSQLFSESQSRFLVSVKPENEAAFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|47093695|ref|ZP_00231448.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes str. 4b H7858]
gi|47017926|gb|EAL08706.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes str. 4b H7858]
Length = 739
Score = 327 bits (837), Expect = 3e-87, Method: Composition-based stats.
Identities = 234/721 (32%), Positives = 356/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELN 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEESFVPVMEDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLTTEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F ++ LF E+ LV +K EN +AF + ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ELNQLFSESQSRFLVSVKPENEAAFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|16800947|ref|NP_471215.1| phosphoribosylformylglycinamidine synthetase I [Listeria innocua
Clip11262]
gi|20139530|sp|Q92AN9|PURL_LISIN Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|16414382|emb|CAC97111.1| phosphoribosylformylglycinamidine synthetase I [Listeria innocua]
Length = 739
Score = 327 bits (837), Expect = 3e-87, Method: Composition-based stats.
Identities = 235/721 (32%), Positives = 356/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELH 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGKVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEDAFVPVIDDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLATEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F ++ LF E+ LV +K EN +AF K ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ELNQLFSESQSRFLVSVKPENEAAFAKLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|153202728|ref|ZP_01944205.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes HPB2262]
gi|133735165|gb|EBA36863.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes HPB2262]
Length = 739
Score = 327 bits (837), Expect = 3e-87, Method: Composition-based stats.
Identities = 234/721 (32%), Positives = 356/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELN 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEESFVPVMEDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLTTEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F ++ LF E+ LV +K EN +AF + ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ELNQLFSESQSRFLVSVKPENEAAFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|16803809|ref|NP_465294.1| phosphoribosylformylglycinamidine synthetase I [Listeria
monocytogenes EGD-e]
gi|20139469|sp|Q8Y6C1|PURL_LISMO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|16411223|emb|CAC99847.1| phosphoribosylformylglycinamidine synthetase I [Listeria
monocytogenes]
Length = 739
Score = 326 bits (835), Expect = 4e-87, Method: Composition-based stats.
Identities = 235/721 (32%), Positives = 355/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELH 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP--DLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPTRYQAFQEEEAFVPAMDDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLVTEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GAE++ F + LF E+ LV +K EN +AF + ME +Y +
Sbjct: 649 EATFKAGLGAEVEVPF-------ALNQLFSESQSRFLVSVKPENEAAFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|108803837|ref|YP_643774.1| phosphoribosylformylglycinamidine synthase II [Rubrobacter
xylanophilus DSM 9941]
gi|108765080|gb|ABG03962.1| phosphoribosylformylglycinamidine synthase II [Rubrobacter
xylanophilus DSM 9941]
Length = 727
Score = 325 bits (833), Expect = 7e-87, Method: Composition-based stats.
Identities = 228/675 (33%), Positives = 348/675 (51%), Gaps = 47/675 (6%)
Query: 97 DAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSAR 156
+ P VL +NAG++E + + ++FK E+HNHPSA+EP+ GA TGVGG+IRD++ V AR
Sbjct: 59 EGPRVLQGPGENAGVVEVGDGWALAFKVESHNHPSAVEPYEGAATGVGGIIRDILAVGAR 118
Query: 157 PFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAY 216
P A+ D L FG P + + V+ G+ YGN +G+PTV G V + AY
Sbjct: 119 PVALLDSLRFG---------PLEEERNRYLFREVVRGIGGYGNAVGVPTVGGEVEFAPAY 169
Query: 217 ASNPLVYCGCAGIAPRGKH-RTKPSA-GDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
+ NPLV C G+ K R++ S G+ ++ LG +TGRDG+ GATF+S + +G+
Sbjct: 170 SGNPLVNAMCVGLVRAEKLVRSRASGEGNLVVLLGSRTGRDGIHGATFASDELGEGSGE- 228
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLA 332
S+VQ+G+P +K + E + ++ L A+ D GA G +S+ EMA+ +G +++
Sbjct: 229 RRSNVQVGDPFAEKMLIECCLALLEEDLLVALQDLGAAGITSSASEMAAKGGVGIEIETD 288
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
++P++ +G+ PWE+ +SE+QERM+ V +LE + L V +GR G LRV
Sbjct: 289 RVPLREEGMEPWEVMISESQERMLAVVEPGRLERVAGLARRYGVGAAVIGRVAGHGELRV 348
Query: 393 RFGEKEIINLSCGFLHSGPPQRKLKAAPPK-DGKPFIKYPEYKEP-DLNAALKAVINHHA 450
G + + ++ L P + P DG + P D AAL +++H
Sbjct: 349 VHGGEVVGSVPARHLADAPVYEREVVRPAYLDGARALDLASVPPPGDYGAALLGLLSHPN 408
Query: 451 VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQG 510
+ S+ + YDHEV TVLRP DAAV++ T ++ A++ R
Sbjct: 409 LRSRRSVYEQYDHEVGTCTVLRP--------GADAAVMRIRGT--RRGYALTTDGRGRHC 458
Query: 511 LLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTA 570
LDP A+ + EA RN GA+P A+ + G+P + E + L E
Sbjct: 459 YLDPRGGGAATVAEAYRNLSCVGAEP--VALTNCLNFGNPEKAEGYYQLAECIEGMAGAC 516
Query: 571 LVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYL 630
TP +SG S N E +R ++ P+ ++ +G++ D+ R + K+EG A+ L
Sbjct: 517 EALGTPVVSGNVSLYN-----ETERGAVHPTPVVGMVGLLEDVRRHATPEIKREGDALVL 571
Query: 631 VGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSE 688
VG+ + S GS + E G PP +E + + + GLV + HDLS+
Sbjct: 572 VGRFRPSLAGSAYLE---AAHGLVRGAPPSPDLPSEKAAADAVRAAVAAGLVDTAHDLSD 628
Query: 689 GGLAAALYEMCL-SGIGAELKEDFHTRL--GASKIASLFGETTGCLLVEIKEENRSAFEK 745
GGLA AL EM + GIGAE RL GA + +LFGE GC+LV + EE E
Sbjct: 629 GGLAVALAEMAVGGGIGAE------ARLLPGARQDVALFGECGGCILVAVPEERLEELEG 682
Query: 746 EMEGASIYEIGKTCG 760
+ G IG+T G
Sbjct: 683 ALAGVPRARIGRTGG 697
>gi|153174960|ref|ZP_01930395.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes FSL N3-165]
gi|133729817|gb|EBA31515.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes FSL N3-165]
Length = 739
Score = 325 bits (832), Expect = 9e-87, Method: Composition-based stats.
Identities = 233/721 (32%), Positives = 354/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELN 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEEAFVPVIDDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLATEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F + LF E+ LV +K EN + F + ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ALNQLFSESQSRFLVSVKPENEATFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|89209625|ref|ZP_01188020.1| Phosphoribosylformylglycinamidine synthase II [Halothermothrix
orenii H 168]
gi|89160694|gb|EAR80347.1| Phosphoribosylformylglycinamidine synthase II [Halothermothrix
orenii H 168]
Length = 733
Score = 325 bits (832), Expect = 1e-86, Method: Composition-based stats.
Identities = 245/740 (33%), Positives = 364/740 (49%), Gaps = 78/740 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R + E WSEHC +K KA + + +P
Sbjct: 30 REPNELELGLFGVMWSEHCGYKNSKAVL------------RNFP---------------- 61
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
+ VL +NAGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRD+ +
Sbjct: 62 --TEGEQVLQGPGENAGIVDIGDNKAVVFKIESHNHPSAIEPYQGAATGVGGIIRDIFTM 119
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A+ D L FG D E V + I SGV+ G+ DYGN +GIPTV G ++H
Sbjct: 120 GARPIALLDSLRFGPLD--EERV-------RYIFSGVVSGISDYGNSIGIPTVGGETYFH 170
Query: 214 EAYASNPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDAS 270
+AY NPLV C G+ K K A G+ ++ +G TGRDG++GA+F+S +
Sbjct: 171 KAYKGNPLVNAMCVGLVDH-KDIIKAVARGVGNPVMVVGATTGRDGIQGASFASEELSED 229
Query: 271 TGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCD 328
+ + SVQ+G+P ++K + E ++ I D GA G S+ EMAS G +
Sbjct: 230 S-EERRPSVQVGDPFMEKLLLEACLELYKTDAVVGIQDMGAAGLISSSCEMASRAGSGME 288
Query: 329 VDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDA 388
+D++++P++ GL P+E+ LSE+QERM++ + + ++K+ + +GR T D
Sbjct: 289 LDVSQVPLREPGLTPYEIMLSESQERMLVVPKKGREDEVKKIFKHWGLNARVIGRVTDDG 348
Query: 389 VLRVRFGEKEIINLSCGFLHSGPPQ-RKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVI 446
+LR++ GE + + +L P R+ K D + + P D N L ++
Sbjct: 349 ILRIKNGEDVVAEVPAHYLAEAPEYVREGKRPAWLDEENKLDLESLPLPDDYNKVLLEML 408
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
+ + SKE I YDH VQ T++ P DAAV++ TE +A+A++ N
Sbjct: 409 DSPNLASKEWIYSQYDHMVQNNTMVLP--------GSDAAVLRIKGTE--RAIAVTTDSN 458
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSC 566
R LDP A+ EA RN V +G P AI D G+P + E W E
Sbjct: 459 GRYFYLDPRQGGKLAVAEAARNIVCSGGQP--LAITDGLNFGNPEKEEIYWQFKEAVAGI 516
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
L TP +SG SF NE+ EGK +I P+ ++ +G++ FK EG
Sbjct: 517 SEACLALGTPVVSGNVSFYNEH---EGK--AIYPTPIVGMIGVLEKQEYATDIAFKDEGD 571
Query: 627 AIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF--KKEAAELYKKLHSNIMKGLVLSCH 684
+YL+G+ + GGS E + + +PP +E L L + I +GLV S H
Sbjct: 572 LVYLIGETREELGGS---EYLSVIHDKDRGLPPTLDLEEEKRLQSSLLTLIQEGLVKSAH 628
Query: 685 DLSEGGLAAALYEMCLSG-IGAELK-EDFHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
D +EGGL AL E CL+G +GA ++ DF R A LFGE+ +L+ I ++
Sbjct: 629 DCAEGGLTIALTECCLTGDLGAIIELGDFQIR----PDAMLFGESASRVLITISPGDKEK 684
Query: 743 FEKEME--GASIYEIGKTCG 760
E ++ G IGKT G
Sbjct: 685 AESVLQESGLKYRNIGKTGG 704
>gi|153007199|ref|YP_001381524.1| phosphoribosylformylglycinamidine synthase II [Anaeromyxobacter sp.
Fw109-5]
gi|152030772|gb|ABS28540.1| phosphoribosylformylglycinamidine synthase II [Anaeromyxobacter sp.
Fw109-5]
Length = 767
Score = 323 bits (829), Expect = 2e-86, Method: Composition-based stats.
Identities = 243/748 (32%), Positives = 355/748 (47%), Gaps = 91/748 (12%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + + K +P P
Sbjct: 35 ELGVFSVMWSEHCSYKSSRVHL------------KTFP------------------TSGP 64
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
VL +NAG+++ + +FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 65 RVLQGPGENAGVVDLGDGLAAAFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPIA 124
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKR--IISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
+ L FG P HPK ++ GV+ G+ YGN MG+PTV G V +H +Y
Sbjct: 125 SANSLRFGDPS-----------HPKTAYLLEGVVAGIGGYGNCMGVPTVAGEVMFHPSYN 173
Query: 218 SNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
N LV GI P K T G+ ++ +G KTGRDG+ GAT +S DAST +
Sbjct: 174 GNCLVNAFTLGILPADKIFLGTAAGVGNPVMYIGAKTGRDGIHGATMASAEFDASTEE-K 232
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAK 333
+VQ+G+P ++K + E ++ I D GA G++S+ EMA + G D+ L +
Sbjct: 233 RPTVQVGDPFMEKLLLEACLELFKTDAVVGIQDMGAAGFTSSSVEMAGRAGNGLDLFLDQ 292
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P++ +G+ P+E+ LSE+QERM++ K + ++K+C D+++ +GR TG R
Sbjct: 293 VPLREEGMTPYEILLSESQERMLLVAAEGKEDMVRKICTKWDLDVAIVGRVTGTGRWRAH 352
Query: 394 FGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINHHA 450
+ K + +L L G P QR + P EP DL L ++
Sbjct: 353 WHGKVVADLPVDPLTEGAPKYQRPMTPHPALPALHAFDLSTVPEPADLGDTLLRLLARPT 412
Query: 451 VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPM---ETEGKKAVAISNALNP 507
+ SKE + + YDH V+ +RP DAAV++ E K +AIS N
Sbjct: 413 IASKEWVYQQYDHMVRLVGAVRP--------GGDAAVVRIATGDERHAGKGIAISVGANG 464
Query: 508 RQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCY 567
R LDP+ A A+ E RN G +P A+ D G+P +PE MW E R
Sbjct: 465 RYCFLDPHLGAQHAVAECARNIACVGGEP--IAVTDCLNFGNPEKPEIMWQFAECVRGIG 522
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+ TP +SG S NE +EG+ I P+ I +G++PD+ + S FK G
Sbjct: 523 DACRALGTPVVSGNVSLYNE---TEGQ--GILPTPTIGMVGLLPDVEKTCTSAFKNAGDV 577
Query: 628 IYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLHSNIMKGLVLSCHD 685
I LVG Q GGS E G A PP A E + + + + +GL+ S HD
Sbjct: 578 IALVGTLQGEVGGS---EYLSAEHGREAGHPPALDLAKEKAVQETVRRAVREGLLSSAHD 634
Query: 686 LSEGGLAAALYEMCL-----------SGIGAELKEDFHTRLGASKIASLFGETTGCLLVE 734
S+GGLA AL E C+ IGA ++ F R K LFGE +LV
Sbjct: 635 CSDGGLAVALAECCMMHGVPAGAEKAPWIGAAVRVPFPAR----KDFVLFGEDASRILVS 690
Query: 735 IKEENRSAFEKEME--GASIYEIGKTCG 760
+ +E+ + F + GA + +G G
Sbjct: 691 MPKESAARFVALAQECGAPVIRLGAVGG 718
>gi|116512323|ref|YP_809539.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lactococcus lactis subsp. cremoris SK11]
gi|116107977|gb|ABJ73117.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lactococcus lactis subsp. cremoris SK11]
Length = 739
Score = 323 bits (829), Expect = 2e-86, Method: Composition-based stats.
Identities = 248/737 (33%), Positives = 357/737 (48%), Gaps = 83/737 (11%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K + K +P P VL
Sbjct: 48 AVMWSEHCCYKNSKPVL------------KKFP------------------TTGPQVLMG 77
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AG+++ + V FKAE+HNHPS +EP+ GA TG GG+IRD+ + ARP A+ D L
Sbjct: 78 PGEGAGVVDIGDDLAVVFKAESHNHPSYVEPYEGAATGSGGIIRDIFSMGARPIAILDSL 137
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG P +N + I+ V G+ YGN +GIPTV G V + E+YA NPLV
Sbjct: 138 RFG----PIDNGKT-----RHIVDQVTAGIAGYGNCIGIPTVGGEVAFDESYAGNPLVNV 188
Query: 225 GCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQI 281
C G+ KH K A G+ I +G KTGRDG+ GA+F+S S + S+VQ+
Sbjct: 189 MCVGLIEH-KHIQKGQAKGVGNSIFYVGAKTGRDGIHGASFASKEF-GSGSETQRSAVQV 246
Query: 282 GEPIIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCD--VDLAKIPVK 337
G+P ++K + E I+ ++ G + I D GA G S+ EMAS G ++L +P +
Sbjct: 247 GDPFMEKLLLEACIEVIQNHGDILVGIQDMGAAGLVSSTSEMASKAGSGLRLNLDNVPQR 306
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
+ P+E+ LSE+QERMV+ V + + L D++ N+G T D + +
Sbjct: 307 ETEMIPYEMMLSESQERMVLCVKKGHEQEIIDLFKKYDLDAVNIGEVTDDGFYTLYHKGQ 366
Query: 398 EIINLSCGFLHSGPPQRKLKAAPPKDGKPFI---KY-PEYKEPDLNAALKAVINHHAVNS 453
+ ++ L P +A P+ + F KY PE + ++ K ++ + S
Sbjct: 367 MVAHVPVDSLAEDAPTYYREAKVPERIQKFTDSEKYLPEITDSAVSEIFKKLLAQPTIAS 426
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
K+ I YD V TV+ P DAAV++ T KA+A++ N R LD
Sbjct: 427 KKSIYETYDSRVMTNTVVAP--------GSDAAVLRVRGT--NKALAMTTDCNARYLYLD 476
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVF 573
P A A+ EA RN VA+G P AI D G+P +PE W L A + L
Sbjct: 477 PEKGGAIAVAEAARNIVASGGKP--LAITDCLNFGNPEKPEQFWELTTAADGISRSCLAL 534
Query: 574 KTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGK 633
TP ISG S NE S +I P+ +I +G++ D+ + +FKK G I LVG+
Sbjct: 535 DTPVISGNVSLYNETNGS-----AILPTPMIGMVGLIEDVKNITTQEFKKAGDLIVLVGQ 589
Query: 634 PQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLA 692
F GS EL + +GE + F E ++ + + I GL+ S HDLSEGGLA
Sbjct: 590 TFDDFSGS---ELQKMLTGEISGKIDFDLETEKVNQDFVLKAITDGLINSAHDLSEGGLA 646
Query: 693 AALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM--EG 749
AL E + G+G +++ D A LF ET G ++ I EN++AFEK +
Sbjct: 647 IALAESAFANGLGIDVEVDLSN-------AQLFSETQGRFVLSISPENQAAFEKLLTESS 699
Query: 750 ASIYEIGKTCGKAGLKL 766
AS IGK LK+
Sbjct: 700 ASSEVIGKVTDNGILKI 716
>gi|47095696|ref|ZP_00233303.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes str. 1/2a F6854]
gi|153179790|ref|ZP_01932986.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes F6900]
gi|153185520|ref|ZP_01936090.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes J0161]
gi|153191236|ref|ZP_01938498.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes J2818]
gi|47015981|gb|EAL06907.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes str. 1/2a F6854]
gi|126941878|gb|EBA19755.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes J0161]
gi|127765397|gb|EBA25746.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes J2818]
gi|133732631|gb|EBA34329.1| phosphoribosylformylglycinamidine synthase II [Listeria
monocytogenes F6900]
Length = 739
Score = 323 bits (829), Expect = 2e-86, Method: Composition-based stats.
Identities = 233/721 (32%), Positives = 354/721 (49%), Gaps = 80/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P + VL +
Sbjct: 50 WSEHCSYKNSKPVL------------RKFP------------------TEGKQVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPS +EP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 80 GAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP H K ++S V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 140 ELDTP---------HAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K K A G+ ++ +G KTGRDG+ GATF+S V + G+ S+VQ+G+P
Sbjct: 191 GLI-EAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFAS-VEFSEEGEQQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIPVKYQG 340
++K + E +D RD + I D GA G S+ EMAS G ++L +P +
Sbjct: 249 FMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELH 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V +E +Q L + +E +G+ T D + ++ + +
Sbjct: 309 MTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVA 368
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
N+ L P + P + F + + D+ K ++ + SK I
Sbjct: 369 NVPVDALAEDAPVYHKPSKEPARYQAFQEEEAFVPVIDDVVGVWKELLAQPTIASKRHIY 428
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD++V+ T + P DAA+++ TE KA+A++ N R LDP
Sbjct: 429 EQYDYQVRTDTAVVP--------GSDAAIVRVRGTE--KAIAMTTDCNSRYLYLDPEVGG 478
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A A+ EA RN V +G P AI D G+P +PE W + + A L TP I
Sbjct: 479 AIAVAEAARNIVCSGGKP--LAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVI 536
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE ++G I P+ +I +G+V D+ + DFK G I+L+G+ + +
Sbjct: 537 SGNVSLYNE---TDG--TGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEY 591
Query: 639 GGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLAAALY 696
GS EL + G+ S P + Y++ L + I +GLV S HDL+EGG AL
Sbjct: 592 SGS---ELQKLQQGKISGRAPELDLATEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALA 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
E +G+GA+++ F + LF E+ LV +K EN + F + ME +Y +
Sbjct: 649 EATFKAGLGADVEVPF-------ALNQLFSESQSRFLVSVKPENEATFAQLMELEKVYRL 701
Query: 756 G 756
G
Sbjct: 702 G 702
>gi|138893919|ref|YP_001124372.1| Phosphoribosylformylglycinamidine synthase II [Geobacillus
thermodenitrificans NG80-2]
gi|134265432|gb|ABO65627.1| Phosphoribosylformylglycinamidine synthase II [Geobacillus
thermodenitrificans NG80-2]
Length = 742
Score = 323 bits (829), Expect = 2e-86, Method: Composition-based stats.
Identities = 231/721 (32%), Positives = 351/721 (48%), Gaps = 82/721 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + K +P D P VL +
Sbjct: 51 WSEHCSYKNSKPVL------------KKFP------------------TDGPHVLQGPGE 80
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V+FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 81 GAGIVDIGDGLAVAFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIALLNSLRFG 140
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
+P K + V+ G+ YGN +GIPTV G V + AY NPLV C
Sbjct: 141 ELTSP---------RVKYLFEHVVAGIAGYGNCIGIPTVGGEVQFDPAYEGNPLVNAMCV 191
Query: 228 GIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
GI + G+ ++ +G KTGRDG+ GATF+S + + + +VQ+G+P
Sbjct: 192 GIIRHEDIQRGVATGVGNTVMYVGAKTGRDGIHGATFASEELSEQS-EAKRPAVQVGDPF 250
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
++K + E ++A I D GA G +S+ EMAS G +++L +P + G+ P
Sbjct: 251 MEKLLLEACLEAVKSDALVGIQDMGAAGLTSSSAEMASKGGFGIEMNLDLVPQRETGMTP 310
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ V + E + + +E +G+ T D +LR+ F + + +
Sbjct: 311 YEMMLSESQERMLLVVEQGREEEIAAIFAKYGLEAKAIGKVTDDKMLRLFFHGEVVAEIP 370
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYPEY--KEPDLNAALKAVINHHAVNSKEDIVRLY 461
L P +A P + F P Y + D N L ++ + SKE + Y
Sbjct: 371 VDALAKDAPVYHKPSAEPDYYREFQAMPTYIPQIEDYNRTLLGLLAQPTIASKEWVYDQY 430
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASA 521
D+ V+ TV+ P DAAV++ T KA+A++ N R LDP A
Sbjct: 431 DYMVRTNTVVAP--------GSDAAVVRIRGT--NKALALTTDCNSRYLYLDPEMGGKIA 480
Query: 522 IDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGK 581
+ EA RN V +GA P AI D G+P +P+ W L + TP +SG
Sbjct: 481 VAEAARNVVCSGAKP--LAITDCLNFGNPEKPDIFWQLEKAVDGMSEACRTLGTPVVSGN 538
Query: 582 DSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGS 641
S NE + G+ ++ P+ ++ +G+V D+ V FK+ G IY++G+ + FGGS
Sbjct: 539 VSLYNE---TNGE--AVYPTPVVGMVGLVDDLSHVTTQPFKQAGDLIYVIGEAKPEFGGS 593
Query: 642 VF-----AELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALY 696
+FG AV A ++L + I G+V S HD++EGGLA AL
Sbjct: 594 ELQKWLEGRIFGKAPELDLAV------EASRQRQLLTAIRAGVVASAHDVAEGGLAVALA 647
Query: 697 EMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYE 754
E + SG+GA + + ++ LF ET +V +K+E++ AFE+ +E I E
Sbjct: 648 ECVIGASGLGANVT------VSGDLVSELFSETQSRFVVSVKKEHQEAFEQLVEAKLIGE 701
Query: 755 I 755
+
Sbjct: 702 V 702
>gi|125623815|ref|YP_001032298.1| phosphoribosylformylglycinamidine synthase II [Lactococcus lactis
subsp. cremoris MG1363]
gi|14916686|sp|Q9ZB06|PURL_LACLC Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|4097533|gb|AAD12626.1| phosphoribosylformylglycinamidine synthetase II [Lactococcus
lactis]
gi|124492623|emb|CAL97568.1| phosphoribosylformylglycinamidine synthase II [Lactococcus lactis
subsp. cremoris MG1363]
Length = 739
Score = 323 bits (827), Expect = 4e-86, Method: Composition-based stats.
Identities = 248/737 (33%), Positives = 357/737 (48%), Gaps = 83/737 (11%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K + K +P P VL
Sbjct: 48 AVMWSEHCCYKNSKPVL------------KKFP------------------TTGPQVLMG 77
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AG+++ + V FKAE+HNHPS +EP+ GA TG GG+IRD+ + ARP A+ D L
Sbjct: 78 PGEGAGVVDIGDDLAVVFKAESHNHPSYVEPYEGAATGSGGIIRDIFSMGARPIAILDSL 137
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG P +N + I+ V G+ YGN +GIPTV G V + E+YA NPLV
Sbjct: 138 RFG----PIDNGKT-----RHIVDQVTAGIAGYGNCIGIPTVGGEVAFDESYAGNPLVNV 188
Query: 225 GCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQI 281
C G+ KH K A G+ I +G KTGRDG+ GA+F+S S + S+VQ+
Sbjct: 189 MCVGLIEH-KHIQKGQAKGVGNSIFYVGAKTGRDGIHGASFASKEF-GSGSETQRSAVQV 246
Query: 282 GEPIIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCD--VDLAKIPVK 337
G+P ++K + E I+ ++ G + I D GA G S+ EMAS G ++L +P +
Sbjct: 247 GDPFMEKLLLEACIEVIQNHGDILVGIQDMGAAGLVSSTSEMASKAGSGLRLNLDNVPQR 306
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
+ P+E+ LSE+QERMV+ V + + L D++ N+G T D + +
Sbjct: 307 ETEMIPYEMMLSESQERMVLCVKKGHEQEIIDLFKKYDLDAVNIGEVTDDGFYTLYHKGQ 366
Query: 398 EIINLSCGFLHSGPPQRKLKAAPPKDGKPFI---KY-PEYKEPDLNAALKAVINHHAVNS 453
+ ++ L P +A P+ + F KY PE + ++ K ++ + S
Sbjct: 367 MVAHVPVDSLAEDAPTYYREAKVPERIQKFTDSEKYLPEITDSAVSEIFKKLLAQPTIAS 426
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
K+ I YD V TV+ P DAAV++ T KA+A++ N R LD
Sbjct: 427 KKSIYETYDSRVMTNTVVAP--------GSDAAVLRVRGT--NKALAMTTDCNARYLYLD 476
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVF 573
P A A+ EA RN VA+G P AI D G+P +PE W L A + L
Sbjct: 477 PEKGGAIAVAEAARNIVASGGKP--LAITDCLNFGNPEKPEQFWELTTAADGISRSCLAL 534
Query: 574 KTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGK 633
TP ISG S NE S +I P+ +I +G++ D+ + +FKK G I LVG+
Sbjct: 535 DTPVISGNVSLYNETNGS-----AILPTPMIGMVGLIEDVKNITTQEFKKAGDLIVLVGQ 589
Query: 634 PQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLA 692
F GS EL + +GE + F E ++ + + I GL+ S HDLSEGGLA
Sbjct: 590 IFDDFSGS---ELQKMLTGEISGKIDFDLETEKVNQDFVLKAITDGLINSAHDLSEGGLA 646
Query: 693 AALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM--EG 749
AL E + G+G +++ D A LF ET G ++ I EN++AFEK +
Sbjct: 647 IALAESAFANGLGIDVEVDLSN-------AQLFSETQGRFVLSISPENQAAFEKLLTESS 699
Query: 750 ASIYEIGKTCGKAGLKL 766
AS IGK LK+
Sbjct: 700 ASSEVIGKVTDNGILKI 716
>gi|20807293|ref|NP_622464.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Thermoanaerobacter tengcongensis MB4]
gi|22096003|sp|Q8RBK5|PURL_THETN Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|20515803|gb|AAM24068.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Thermoanaerobacter tengcongensis MB4]
Length = 733
Score = 322 bits (826), Expect = 5e-86, Method: Composition-based stats.
Identities = 237/701 (33%), Positives = 353/701 (50%), Gaps = 74/701 (10%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K ++K K I P +
Sbjct: 38 WSEHCSYKNSKP------------------------LLKYLPTKGERVIQGPG------E 67
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
NAG+++ + V K E+HNHPSAIEP+ GA TGVGG+IRD+ + ARP A+ D L FG
Sbjct: 68 NAGVLDIGDNLAVVMKIESHNHPSAIEPYQGAATGVGGIIRDIFTMGARPIALLDSLRFG 127
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
PD K +I V+ G+ DYGN +GIPTV G ++ E+Y NPLV C
Sbjct: 128 IPDDK---------RTKYLIENVVAGIADYGNCIGIPTVGGDTYFEESYKGNPLVNAMCV 178
Query: 228 GIAPRGKHRT--KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
GI + K + G+ ++ +G TGRDG+ GA+F+S + + + SVQ+G+P
Sbjct: 179 GIVEKDKIKKGIAKGIGNPVMVVGATTGRDGIGGASFASQELSEES-EEKRPSVQVGDPF 237
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
++K + E ++ + AI D GA G +S+ EMAS +G ++DL K+P++ +G+ P
Sbjct: 238 MEKLLLEACLELFETDAVVAIQDMGAAGLTSSSCEMASRGGVGMEIDLDKVPLREEGMTP 297
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ V K E +QK+ + +G+ T D ++RV K + +
Sbjct: 298 YEIMLSESQERMLVVVKKGKEEDVQKIFKKWGLNAATIGKITDDGMIRVIKDGKIVAEVP 357
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYP--EYKEP-DLNAALKAVINHHAVNSKEDIVRL 460
L PQ + PK + K E K P D+N LK VI+ + SKE I
Sbjct: 358 AKSLTEDAPQYVREEEVPKWQEEVKKLDINEVKPPEDMNKVLKDVISSLNIASKEWIYSQ 417
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YD+ V+ TV+ P DAAV++ T +KA+A++ N R LDPY +
Sbjct: 418 YDYMVRTDTVITP--------GMDAAVVRIKGT--RKAIALTTDCNGRYCYLDPYIGSQI 467
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
A+ EA RN GA P + D G+P + E W L F+ P +SG
Sbjct: 468 AVAEAARNLCMVGAKP--IGVTDCLNFGNPEKKEIYWQLKNSIFGIAKACETFQIPVVSG 525
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
S NE +EG+ +I P+ +I G++ D+ ++ DFKKE I ++G+ + GG
Sbjct: 526 NVSLYNE---NEGE--AIYPTPVIGMAGLIEDVSKICTMDFKKERDVIIILGENKGEIGG 580
Query: 641 SVFAEL-FGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEM 698
S + ++ FG+ G+ + K K EL KL I +GL+ S HD+SEGG AAAL E
Sbjct: 581 SEYLKVCFGMVKGQPPQIDLEKEKRLQELVLKL---IDEGLINSSHDISEGGFAAALVES 637
Query: 699 CLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEE 738
++G GA++ T L A LF E+ L+ + E
Sbjct: 638 AIAGKKGAKIS--LQTSLRAD--IELFSESQSRALITVSPE 674
>gi|56418798|ref|YP_146116.1| phosphoribosylformylglycinamidine synthase subunit II [Geobacillus
kaustophilus HTA426]
gi|67460753|sp|Q5L3D2|PURL_GEOKA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|56378640|dbj|BAD74548.1| phosphoribosylformylglycinamidine (FGAM) synthasecomponent II
(synthetase domain) [Geobacillus kaustophilus HTA426]
Length = 742
Score = 320 bits (821), Expect = 2e-85, Method: Composition-based stats.
Identities = 229/720 (31%), Positives = 354/720 (49%), Gaps = 74/720 (10%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K + K +P D P VL
Sbjct: 48 AVMWSEHCSYKNSKPVL------------KKFP------------------TDGPHVLQG 77
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AGI++ + V+FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+ + L
Sbjct: 78 PGEGAGIVDIGDGLAVAFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIALLNSL 137
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG +P K + V+ G+ YGN +GIPTV G V + AY NPLV
Sbjct: 138 RFGELTSP---------RVKYLFEQVVAGIAGYGNCVGIPTVGGEVQFDPAYEGNPLVNA 188
Query: 225 GCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG 282
C GI + G+ ++ +G KTGRDG+ GATF+S + + + +VQ+G
Sbjct: 189 MCVGIIRHEDIQRGVATGVGNTVMYVGAKTGRDGIHGATFASEELSEQS-EAKRPAVQVG 247
Query: 283 EPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQG 340
+P ++K + E ++A I D GA G +S+ EMAS G +++L +P + G
Sbjct: 248 DPFMEKLLLEACLEAVKSDALVGIQDMGAAGLTSSSAEMASKGGFGIEMNLDLVPQREAG 307
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ V + + + +E +G+ T D +LR+ F +
Sbjct: 308 MTPYEMMLSESQERMLLVVKQGCEDEIAAIFAKYGLEAKAIGKVTDDKMLRLLFRGEVAA 367
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE--PDLNAALKAVINHHAVNSKEDIV 458
+ L P +A P + F P Y D N L ++ + SKE +
Sbjct: 368 EIPVDALAKDAPVYHKPSAEPAYYREFQAMPPYTPHIEDYNQTLLGLLAQPTIASKEWVY 427
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YD+ V+ TV+ P DAAV++ KA+A++ N R LDP
Sbjct: 428 DQYDYMVRTNTVVAP--------GSDAAVVRIRGM--NKALALTTDCNSRYLYLDPETGG 477
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A+ EA RN + +GA P AI D G P +PE W L + TP +
Sbjct: 478 KIAVAEAARNVICSGAKP--LAITDCLNFGSPEKPEIFWQLEKAVDGMSEACRALGTPVV 535
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG S NE + G+ ++ P+ ++ +G++ D+ + FK+ G IY++G+ + F
Sbjct: 536 SGNVSLYNE---TNGE--AVYPTPVVGMVGLIDDLSHITTQSFKQAGDLIYVIGEAKPEF 590
Query: 639 GGSVFAE-LFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
GGS + L G G++ + + EA+ ++L + I G+V S HD++EGGLA AL E
Sbjct: 591 GGSELQKWLEGRIFGKAPEI-DLEVEASR-QRQLLAAIRAGVVASAHDIAEGGLAVALAE 648
Query: 698 --MCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEI 755
M SG+GA++ +G ++ LF ET ++ +K+E++ AFE+ +E I E+
Sbjct: 649 CVMGASGLGAKVT------IGGDLVSELFSETQSRFVISVKKEHQEAFEQLVEAKRIGEV 702
>gi|119509347|ref|ZP_01628496.1| Phosphoribosylformylglycinamidine synthase II [Nodularia spumigena
CCY9414]
gi|119465961|gb|EAW46849.1| Phosphoribosylformylglycinamidine synthase II [Nodularia spumigena
CCY9414]
Length = 793
Score = 320 bits (820), Expect = 3e-85, Method: Composition-based stats.
Identities = 236/771 (30%), Positives = 361/771 (46%), Gaps = 94/771 (12%)
Query: 27 EFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIK 86
E K R AE WSEHC +K + + K +P
Sbjct: 26 EIVKRLGRHPNKAELGMFGVMWSEHCCYKNSRPLL------------KQFP--------- 64
Query: 87 TYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGV 146
P +L +NAG+++ + +++FK E+HNHPSA+EPF GA TGVGG+
Sbjct: 65 ---------TTGPRILVGPGENAGVVDIGDGRQLAFKIESHNHPSAVEPFQGAATGVGGI 115
Query: 147 IRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTV 206
+RD+ + ARP A+ + L FG D P +R+ +GV+ G+ YGN +G+PTV
Sbjct: 116 LRDIFTMGARPIALLNSLRFGDLDDPKT---------QRLFTGVVAGISHYGNCVGVPTV 166
Query: 207 NGGVHYHEAYASNPLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSS 264
G V++ +AY+ NPLV G+ P G+ ++ +G TGRDG+ GA+F+S
Sbjct: 167 GGEVYFDKAYSGNPLVNVMALGLMETPEIVKSGASGFGNPVLYVGSTTGRDGMGGASFAS 226
Query: 265 MVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS- 323
+ + D +VQ+G+P I+K + E ++A G A D GA G + + EMA+
Sbjct: 227 AELSEQSLD-NRPAVQVGDPFIEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAAK 285
Query: 324 -ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
+G + DL KIPV+ G+ P+E LSE+QERM+ + + L + + + G
Sbjct: 286 GGVGIEFDLDKIPVRELGMVPYEYLLSESQERMLFVAHKGREQELIDIFERWGLHAVVAG 345
Query: 383 RFTGDAVLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKY-PEY------ 433
+ ++R+ F K + L P +R+L A PP+ + K+ P+Y
Sbjct: 346 TVIAEPIVRILFQGKIAAEIPAEALAENTPLYERELLAEPPEYAREAWKWSPDYLPVCTT 405
Query: 434 -------KEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAA 486
K + L +++ + SK + R YDH+VQ TV+ P DAA
Sbjct: 406 SGIEIQGKLQSWDDVLLTLLDTPTIASKSWVYRQYDHQVQNNTVILPGGA-------DAA 458
Query: 487 VI--KPMETEGKK---------AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGAD 535
V+ +P+ET + VA + NPR LDPY A + + EA RN GA+
Sbjct: 459 VVRLRPLETTQNEKLAPESFTSGVAATVDCNPRYVYLDPYEGAKAVVAEAARNLSCVGAE 518
Query: 536 PEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKR 595
P A+ DN G P +P W L E R L TP G S NE SEG
Sbjct: 519 P--LAVTDNLNFGSPEKPIGYWQLAEACRGLSEGCLELATPVTGGNVSLYNETFDSEGNP 576
Query: 596 VSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKP---QFSFGGSVFAELFGIPSG 652
I P+ ++ +G++PD+ ++ G ++ G IYL+G P S G S E
Sbjct: 577 QPIYPTPVVGMVGLIPDLSKICGQGWQAAGDLIYLLGLPLTSPISLGAS---EYLATIHN 633
Query: 653 ESAAVPP---FKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELK 708
A PP F E + + I G + S HD +EGG+ AL E CL+G +GAE++
Sbjct: 634 TVAGKPPRVDFDLE-RRVQQVCRDGIRAGWIGSAHDSAEGGVVVALAESCLAGNLGAEIQ 692
Query: 709 EDFHTRLGASKIASLFGETTGCLLVEI---KEENRSAFEKEMEGASIYEIG 756
+ LFGE +LV + +++N ++ +E G S ++G
Sbjct: 693 LEISENQLKRLDEVLFGEGGARILVSVTSSEQKNWESYLQEHLGESWQKLG 743
>gi|86160630|ref|YP_467415.1| phosphoribosylformylglycinamidine synthase II [Anaeromyxobacter
dehalogenans 2CP-C]
gi|110826528|sp|Q2IHC1|PURL_ANADE Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|85777141|gb|ABC83978.1| phosphoribosylformylglycinamidine synthase II [Anaeromyxobacter
dehalogenans 2CP-C]
Length = 759
Score = 320 bits (820), Expect = 3e-85, Method: Composition-based stats.
Identities = 244/756 (32%), Positives = 355/756 (46%), Gaps = 94/756 (12%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + WSEHC +K+ + + K +P
Sbjct: 29 RVPTLTELGVFSVMWSEHCSYKSSRVHL------------KTFP---------------- 60
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
P VL +NAG+++ + +FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 61 --TSGPRVLQGPGENAGVVDLGDGLAAAFKMESHNHPSYIEPYQGAATGVGGILRDVFTM 118
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P ++ GV+ G+ YGN MG+PTV G V +H
Sbjct: 119 GARPIASLNALRFGDPSHP---------RTAYLLEGVVAGIGGYGNCMGVPTVGGEVAFH 169
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
+Y N LV GI P K T G+ ++ +G KTGRDG+ GAT +S DAST
Sbjct: 170 PSYNGNCLVNAFTLGILPADKIFRGTAAGVGNPVMYVGAKTGRDGIHGATMASAEFDAST 229
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDV 329
+ +VQ+G+P ++K + E ++ I D GA G +S+ EMA G D+
Sbjct: 230 EE-KRPTVQVGDPFMEKLLLEACLELFQTDAVVGIQDMGAAGLTSSSVEMAGRGGNGLDL 288
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
L K+P++ +G+ P+E+ LSE+QERM++ K E ++ +C+ D+++ +GR T
Sbjct: 289 FLDKVPLREEGMTPYEILLSESQERMLLVAAEGKEELVRSICEKWDLDVAVIGRVTASGR 348
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQ--RKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVI 446
R + + + +L L G P+ R + P EP DL AAL ++
Sbjct: 349 WRAHWRGEVVADLPVDPLTEGAPKYHRPMTPHPALPALHAFDPATLPEPSDLGAALLRLL 408
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK---PMETEGKKAVAISN 503
+ SKE + R YDH V+ +RP DAAV++ E K +A+S
Sbjct: 409 ARPTIASKEWVYRQYDHMVRLVGAVRP--------GGDAAVVRLAVSHEKHAHKGIALSV 460
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
+N R LDPY A A+ E RN G +P AI D G+P +PE MW E
Sbjct: 461 GVNGRFCFLDPYLGAMHAVAECARNIACVGGEP--IAITDCLNFGNPEKPEIMWQFAECV 518
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
R + F TP +SG S NE +EG+ I P+ + +G+V + R S F+
Sbjct: 519 RGIGDACRAFGTPVVSGNVSLYNE---TEGQ--GILPTPTVGMVGLVEPVERTCHSTFRA 573
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLHSNIMKGLVL 681
G + LVG Q GGS E G+ A PP A E + + + + GL+
Sbjct: 574 AGDVVALVGSLQGEVGGS---EYLSAEHGKEAGRPPALDLAREKAVQETVRRAVRAGLLS 630
Query: 682 SCHDLSEGGLAAALYEMCL-----------SGIGAELKEDFHTRLGASKIASLFGETTGC 730
S HD SEGGLA AL E C+ + IG ++ F R K LFGE
Sbjct: 631 SAHDCSEGGLAVALAESCMMHEVPADGSTPAWIGCAVRIPFPVR----KDFVLFGEDASR 686
Query: 731 LLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
+LV + +EN + F E+ + CG ++L
Sbjct: 687 ILVSLPKENAARF---------VELAQECGAPVIRL 713
>gi|15673512|ref|NP_267686.1| phosphoribosylformylglycinamidine synthase II [Lactococcus lactis
subsp. lactis Il1403]
gi|14916660|sp|Q9CFE8|PURL_LACLA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|12724530|gb|AAK05628.1|AE006384_3 phosphoribosylformylglycinamidine synthase II (EC 6.3.5.3)
[Lactococcus lactis subsp. lactis Il1403]
Length = 739
Score = 319 bits (818), Expect = 5e-85, Method: Composition-based stats.
Identities = 243/730 (33%), Positives = 355/730 (48%), Gaps = 83/730 (11%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K + K +P P VL
Sbjct: 48 AVMWSEHCCYKNSKPVL------------KKFP------------------TTGPQVLMG 77
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AG+++ + V FKAE+HNHPS +EP+ GA TG GG+IRD+ + ARP A+ D L
Sbjct: 78 PGEGAGVVDIGDDLAVVFKAESHNHPSYVEPYEGAATGSGGIIRDIFSMGARPIAILDSL 137
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG P +N + I+ V G+ YGN +GIPTV G V + E+YA NPLV
Sbjct: 138 RFG----PIDNGKT-----RHIVDQVTAGIAGYGNCIGIPTVGGEVAFDESYAGNPLVNV 188
Query: 225 GCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQI 281
C G+ KH K A G+ I +G KTGRDG+ GA+F+S S + S+VQ+
Sbjct: 189 MCVGLIEH-KHIQKGQAKGVGNSIFYVGAKTGRDGIHGASFASKEF-GSGSETQRSAVQV 246
Query: 282 GEPIIQKKVAEVLIDA-RDQG-LYSAITDCGAGGYSSAVGEMASALGCD--VDLAKIPVK 337
G+P ++K + E I+ ++ G + I D GA G S+ EMAS G ++L +P +
Sbjct: 247 GDPFMEKLLLEACIEVIQNHGDILVGIQDMGAAGLVSSTSEMASKAGSGLRLNLDNVPQR 306
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
+ P+E+ LSE+QERMV+ V + + L D++ N+G+ T D + +
Sbjct: 307 ETEMIPYEMMLSESQERMVLCVKKGHEQEIIDLFKKYDLDAVNIGQVTDDGFYTLYHKGE 366
Query: 398 EIINLSCGFLHSGPPQRKLKAAPPKDGKPFI---KY-PEYKEPDLNAALKAVINHHAVNS 453
+ ++ L P +A P+ + F KY PE + ++ K ++ + S
Sbjct: 367 MVAHVPVDSLAEDAPTYYREAKVPERIQKFTDSEKYLPEITDSAVSEIFKKLLAQPTIAS 426
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
K+ I YD V TV+ P D+AV++ T KA+A++ N R LD
Sbjct: 427 KKSIYETYDSRVMTNTVVAP--------GSDSAVLRVRGT--NKALAMTTDCNARYLYLD 476
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVF 573
P A A+ EA RN VA+G P AI D G+P +PE W L A + L
Sbjct: 477 PEKGGAIAVAEAARNIVASGGKP--LAITDCLNFGNPEKPEQFWELTTAADGISRSCLAL 534
Query: 574 KTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGK 633
TP ISG S NE S +I P+ +I +G++ ++ + +FKK G I LVG+
Sbjct: 535 DTPVISGNVSLYNETNGS-----AILPTPMIGMVGLIENVKNITTQEFKKAGDLIVLVGQ 589
Query: 634 PQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK-LHSNIMKGLVLSCHDLSEGGLA 692
F GS EL + GE + F E ++ + + I GLV S HDL+EGGLA
Sbjct: 590 TFDDFSGS---ELQKMLIGEISGRIDFDLETEKINQDFVLKAITDGLVSSAHDLAEGGLA 646
Query: 693 AALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGAS 751
AL E + G+G ++K D A LF ET G ++ I EN++ FEK + +S
Sbjct: 647 IALAESAFANGLGVDVKVDITN-------AQLFSETQGRFILSISPENQATFEKLLTESS 699
Query: 752 IYEIGKTCGK 761
+ G+ GK
Sbjct: 700 VS--GEVIGK 707
>gi|76796709|ref|ZP_00779064.1| Phosphoribosylformylglycinamidine synthase II [Thermoanaerobacter
ethanolicus ATCC 33223]
gi|76587922|gb|EAO64339.1| Phosphoribosylformylglycinamidine synthase II [Thermoanaerobacter
ethanolicus ATCC 33223]
Length = 733
Score = 317 bits (813), Expect = 2e-84, Method: Composition-based stats.
Identities = 227/664 (34%), Positives = 336/664 (50%), Gaps = 69/664 (10%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K ++K K I P +
Sbjct: 38 WSEHCAYKNSKP------------------------LLKYLPTKGERVIQGPG------E 67
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
NAG+++ + V K E+HNHPSAIEP+ GA TGVGG+IRD+ + ARP A+ D L FG
Sbjct: 68 NAGVLDIGDNLAVVMKIESHNHPSAIEPYQGAATGVGGIIRDIFTMGARPIALLDSLRFG 127
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
PD K +I V+ G+ DYGN +GIPTV G ++ E+Y NPLV C
Sbjct: 128 IPDDK---------RTKYLIENVVAGIADYGNCIGIPTVGGDTYFEESYKGNPLVNAMCV 178
Query: 228 GIAPRGKHRT--KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
GI + K + G+ ++ +G TGRDG+ GA+F+S + + + SVQ+G+P
Sbjct: 179 GIVEKDKIKKGIAKGIGNPVMIVGATTGRDGIGGASFASQELSEES-EEKRPSVQVGDPF 237
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
++K + E ++ + AI D GA G +S+ EMAS +G ++DL K+P++ +G+ P
Sbjct: 238 MEKLLLEACLELFETDAVVAIQDMGAAGLTSSSCEMASRGGVGMELDLDKVPLREKGMTP 297
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ V K E +QK+ + +G+ T D ++RV K + +
Sbjct: 298 YEIMLSESQERMLVVVEKGKEEDVQKVFKKWGLNAATIGKITDDGMIRVIKEGKIVAEVP 357
Query: 404 CGFLHSGPPQRKLKAAPPK--DGKPFIKYPEYKEP-DLNAALKAVINHHAVNSKEDIVRL 460
L PQ + PK + + E K P D+N ALK VI+ + SKE I
Sbjct: 358 AKSLAEDAPQYIREEEVPKWQEDVNKLNINEVKPPEDMNKALKDVISSLNIASKEWIYSQ 417
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YD+ V+ T + P DAAV++ T KKA+A++ N R LDPY +
Sbjct: 418 YDYMVRTDTAITP--------GMDAAVVRIKGT--KKAIALTTDCNGRYCYLDPYIGSQI 467
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
A+ EA RN GA P + D G+P + E W L + P +SG
Sbjct: 468 AVAEAARNLCMVGAKP--IGVTDCLNFGNPEKKEIYWQLKNSIFGIAKACETLQIPVVSG 525
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
S NE + EG +I P+ +I G++ D+ ++ DFKKE I ++G+ + GG
Sbjct: 526 NVSLYNE--NEEG---AIYPTPVIGMAGLIEDVSKICTMDFKKERDVIIILGENKGEIGG 580
Query: 641 SVFAEL-FGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEM 698
S + ++ FG+ G+ + +K EL KL I KGL+ S HD+SEGG AAAL E
Sbjct: 581 SEYLKVCFGMVKGQPPQIDLEEEKRLQELVLKL---IDKGLINSSHDISEGGFAAALVES 637
Query: 699 CLSG 702
+SG
Sbjct: 638 AISG 641
>gi|114844767|ref|ZP_01455205.1| phosphoribosylformylglycinamidine synthase II [Thermoanaerobacter
ethanolicus X514]
gi|114805191|gb|EAU56994.1| phosphoribosylformylglycinamidine synthase II [Thermoanaerobacter
ethanolicus X514]
Length = 733
Score = 317 bits (812), Expect = 2e-84, Method: Composition-based stats.
Identities = 227/664 (34%), Positives = 336/664 (50%), Gaps = 69/664 (10%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K ++K K I P +
Sbjct: 38 WSEHCAYKNSKP------------------------LLKYLPTKGERVIQGPG------E 67
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
NAG+++ + V K E+HNHPSAIEP+ GA TGVGG+IRD+ + ARP A+ D L FG
Sbjct: 68 NAGVLDIGDNLAVVMKIESHNHPSAIEPYQGAATGVGGIIRDIFTMGARPIALLDSLRFG 127
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
PD K +I V+ G+ DYGN +GIPTV G ++ E+Y NPLV C
Sbjct: 128 IPDDK---------RTKYLIENVVAGIADYGNCIGIPTVGGDTYFEESYKGNPLVNAMCV 178
Query: 228 GIAPRGKHRT--KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
GI + K + G+ ++ +G TGRDG+ GA+F+S + + + SVQ+G+P
Sbjct: 179 GIVEKDKIKKGIAKGIGNPVMIVGATTGRDGIGGASFASQELSEES-EEKRPSVQVGDPF 237
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
++K + E ++ + AI D GA G +S+ EMAS +G ++DL K+P++ +G+ P
Sbjct: 238 MEKLLLEACLELFETDAVVAIQDMGAAGLTSSSCEMASRGGVGMEIDLDKVPLREKGMTP 297
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ V K E +QK+ + +G+ T D ++RV K + +
Sbjct: 298 YEIMLSESQERMLVVVEKGKEEDVQKVFKKWGLNAATIGKITDDGMIRVIKEGKIVAEVP 357
Query: 404 CGFLHSGPPQRKLKAAPPK--DGKPFIKYPEYKEP-DLNAALKAVINHHAVNSKEDIVRL 460
L PQ + PK + + E K P D+N ALK VI+ V SKE I
Sbjct: 358 AKSLAEDAPQYIREEEVPKWQEDVNKLNINEVKPPEDMNKALKDVISSLNVASKEWIYSQ 417
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YD+ V+ T + P DAAV++ T KKA+A++ N R LDPY +
Sbjct: 418 YDYMVRTDTAITP--------GMDAAVVRIKGT--KKAIALTTDCNGRYCYLDPYIGSQI 467
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
A+ EA RN GA P + D G+P + E W L + P +SG
Sbjct: 468 AVAEAARNLCMVGAKP--IGVTDCLNFGNPEKKEIYWQLKNSIFGIAKACETLQIPVVSG 525
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
S NE + EG +I P+ +I G++ D+ ++ DFKKE I ++G+ + GG
Sbjct: 526 NVSLYNE--NEEG---AIYPTPVIGMAGLIEDVSKICTMDFKKERDVIIILGENKGEIGG 580
Query: 641 SVFAEL-FGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEM 698
S + ++ FG+ G+ + +K EL KL I +GL+ S HD+SEGG AAAL E
Sbjct: 581 SEYLKVCFGMVKGQPPQIDLEEEKRLQELVLKL---IEEGLINSSHDISEGGFAAALVES 637
Query: 699 CLSG 702
+SG
Sbjct: 638 AISG 641
>gi|75909841|ref|YP_324137.1| phosphoribosylformylglycinamidine synthase subunit II [Anabaena
variabilis ATCC 29413]
gi|110826529|sp|Q3M6Z4|PURL_ANAVT Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|75703566|gb|ABA23242.1| Phosphoribosylformylglycinamidine synthase II [Anabaena variabilis
ATCC 29413]
Length = 777
Score = 316 bits (810), Expect = 3e-84, Method: Composition-based stats.
Identities = 232/753 (30%), Positives = 350/753 (46%), Gaps = 89/753 (11%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P
Sbjct: 38 AELGMFGVMWSEHCCYKNSRPLL------------KQFP------------------TTG 67
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
P +L +NAG+++ E +++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 68 PRILVGPGENAGVVDLGEGLQLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 127
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
A+ + L FG + P +R+ SGV+ G+ YGN +G+PTV G V++ AY+
Sbjct: 128 ALLNSLRFGSLEDPKT---------QRLFSGVVAGISHYGNCVGVPTVGGEVYFDPAYSG 178
Query: 219 NPLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVM-DASTGDVA 275
NPLV G+ P G+ ++ +G TGRDG+ GA+F+S + D S D
Sbjct: 179 NPLVNVMALGLMETPEIVKSGASGIGNPVLYVGSTTGRDGMGGASFASAELSDESIDD-- 236
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAK 333
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL K
Sbjct: 237 RPAVQVGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAAKGGVGIELDLDK 296
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
IPV+ G+ P+E LSE+QERM+ + + L + ++ G + ++R+
Sbjct: 297 IPVRETGMIPYEYLLSESQERMLFVAHKGREQELIDIFHRWGLQAVVAGTVIAEPIVRIL 356
Query: 394 FGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAA---------- 441
F + L P +R+L A PP+ + ++ P A
Sbjct: 357 FQGAIAAEIPADALAENTPLYERELLAEPPEYARQAWEWSSDSLPTCTTAGIEIQGNLQS 416
Query: 442 ----LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPMETEG 495
L ++N + SK + R YDH+VQ TV P DAAV+ +P+E +G
Sbjct: 417 WQEILLTLLNTPTIASKNWVYRQYDHQVQNNTVFLPGGA-------DAAVVRLRPLEGQG 469
Query: 496 K-----KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP 550
K VA + NPR LDPY A + + EA RN GA+P A+ DN G P
Sbjct: 470 KITNTLSGVAATVDCNPRYVYLDPYEGAKAVVAEAARNLSCVGAEP--LAVTDNLNFGSP 527
Query: 551 NRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIV 610
+P W L E R TP G S NE L +G I P+ ++ +G++
Sbjct: 528 EKPIGYWQLSEACRGLAEGCRELATPVTGGNVSLYNETLDPQGNPQPIYPTPVVGMVGLI 587
Query: 611 PDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP---FKKEAAEL 667
D+ ++ G ++ G IYL+G + G S E A PP F E +
Sbjct: 588 TDLTKICGQGWQTPGDVIYLLGASITTLGAS---EYLATIHDTVAGRPPRVDFDLE-RRV 643
Query: 668 YKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGE 726
K I V S HD +EGGL AL E CL+G +GAE+ D LFGE
Sbjct: 644 QKVCREGIYADWVRSAHDCAEGGLVVALAESCLAGNLGAEIHLDASGSQLQRLDEVLFGE 703
Query: 727 TTGCLLVEI---KEENRSAFEKEMEGASIYEIG 756
+LV + ++EN ++ +E G + ++G
Sbjct: 704 GGARILVSVASTQQENWESYLQEHLGQNWQKLG 736
>gi|94984172|ref|YP_603536.1| phosphoribosylformylglycinamidine synthase II [Deinococcus
geothermalis DSM 11300]
gi|94554453|gb|ABF44367.1| phosphoribosylformylglycinamidine synthase II [Deinococcus
geothermalis DSM 11300]
Length = 746
Score = 316 bits (810), Expect = 4e-84, Method: Composition-based stats.
Identities = 228/670 (34%), Positives = 347/670 (51%), Gaps = 56/670 (8%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
P VL +NAG+++ E + V+FK E+HNHPSA+EP GA TGVGG++RD+ + ARP
Sbjct: 64 GPQVLQGPGENAGVVDIGEGWGVAFKMESHNHPSAVEPVQGAATGVGGILRDIFAMGARP 123
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
FAV D L FG+PD+P + +++GV+EG+ YGN +G+PTV G V +H +Y
Sbjct: 124 FAVLDSLRFGNPDSP---------RTRFLLNGVVEGISHYGNAIGVPTVGGEVTFHPSYQ 174
Query: 218 SNPLVYCGCAGIAPRGKHR-----TKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTG 272
NPLV G+ +H T + G+ I+ +G KTGRDGL GA FSS + A++
Sbjct: 175 ENPLVNVMALGLL---RHEDLAKGTMGAVGNQIVYVGSKTGRDGLGGAVFSSADLSAAS- 230
Query: 273 DVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVD 330
+VQ+G+P ++K + E ++A GL + + D GA G S+ EMA + LG ++
Sbjct: 231 QADRPAVQVGDPFMEKLLLEATLEAIQAGLVAGVQDMGAAGLVSSTCEMAYRAGLGITLE 290
Query: 331 LAKIPVKYQGLAPWELWLSEAQERMV-IAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
L +IP + +G+ P EL LSE+QERM+ + VP + E L L ++++ +G
Sbjct: 291 LDRIPTREEGMVPMELCLSESQERMILVPVPGREQELLDLLARW-ELDVVTIGEVEAHDR 349
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRK-------LKAAPPKD--GKPFIKYPEYKEPDLNA 440
R+ + + + +L L+ P + ++A +D G P DL A
Sbjct: 350 YRLTWRGEVVCDLPVALLNEAPKYTREGVESAEIRAKRERDLSGVPV-------PGDLGA 402
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
L +++H + SK I YDH+V TV+ P DAAV++ ++ VA
Sbjct: 403 VLVELLSHPTIASKRPIFERYDHQVMTNTVVVPG-------AADAAVLRVKGSQ--LGVA 453
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
++ NPR LDPY AA+A+ EA RN GA P AI DN G+P P + L
Sbjct: 454 ATSDCNPRFVYLDPYTGAAAAVAEAARNLACVGATP--LAITDNLNFGNPYEPGVYFQLQ 511
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ + + TP G S N+Y + K V+I P+ I +G++PD+ R D
Sbjct: 512 QSVQGIADACRALNTPVTGGNVSLYNQYAEGDHK-VAIHPTPTIGMVGVLPDVTRRATLD 570
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAE-LFGIPSGESAAVPPFKKE-AAELYKKLHSNIMKG 678
K +YL+G+ + G S + E + G+ +G+ VP E + + + I G
Sbjct: 571 LKPGPHLLYLLGRHATTIGASQYLETVHGLEAGQ---VPDLDLELERRVIEGTLALIRAG 627
Query: 679 LVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEE 738
L + HD SEGGLA AL EM ++G G LK + G A LFGE ++V +
Sbjct: 628 LTDAAHDCSEGGLAVALAEMAMAG-GQGLKVEIKAPAGVRPDALLFGEAHSRIVVAVPLG 686
Query: 739 NRSAFEKEME 748
+ A + +E
Sbjct: 687 HEQAAQDLLE 696
>gi|145622274|ref|ZP_01778235.1| phosphoribosylformylglycinamidine synthase II [Petrotoga mobilis
SJ95]
gi|144947423|gb|EDJ82454.1| phosphoribosylformylglycinamidine synthase II [Petrotoga mobilis
SJ95]
Length = 727
Score = 315 bits (808), Expect = 5e-84, Method: Composition-based stats.
Identities = 229/736 (31%), Positives = 361/736 (49%), Gaps = 106/736 (14%)
Query: 40 EFET--IAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDID 97
EFET + WSEHC +K K Y+KK + +
Sbjct: 34 EFETYLFSAQWSEHCGYKHSKH----------------------------YLKKINESYE 65
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
+ +NAG ++ K V FK E+HNHPSA+EP+ GA TG+GG++RD++ + ARP
Sbjct: 66 S--------ENAGYVQIGGK-AVVFKVESHNHPSAVEPYQGAATGIGGIVRDILAMGARP 116
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A+ D L FG+ P K I GV+ G+ DYGN +G+PTV G ++E Y+
Sbjct: 117 IALLDSLKFGNVFDP---------KVKNIFEGVVSGISDYGNSIGVPTVGGETSFNEIYS 167
Query: 218 SNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
+NPL+ C G+A + + + G ++ +G KTGRDG+ GA+F+S + +G
Sbjct: 168 TNPLINVMCVGVANKNHLASSHADGPDKLLVYVGSKTGRDGIHGASFASKKL---SGKDD 224
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAK 333
SVQ+G+P +K + E ++ A D GA G S+ EMA +GC++ L
Sbjct: 225 RPSVQVGDPFTEKNLIEATLEILKIKGVRACQDMGAAGVLSSTSEMAYKGGVGCELYLDN 284
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF--TGDAVLR 391
IP + + + PWE+ LSE+QERM+ V + ++ +C+ ++ +G+ T V++
Sbjct: 285 IPKRQEDIEPWEIMLSESQERMLFLVNPGTEKKVEAICNKYLIDFAVIGKTISTPHYVVK 344
Query: 392 VRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFI-----KYPEYKEPDLNAALKAVI 446
K + +L L + P + P +I KYP+ K D++ LK ++
Sbjct: 345 ENSEGKVLADLPIDILVNAPEYYRNNTIP----STYILNKAKKYPKTKIKDIDKILKILL 400
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
++H ++SK+ I + YD++V+ T+ P D+AV+ +T+ KA+A++ N
Sbjct: 401 SNHNISSKKWIYQQYDYKVETNTIFIPEQA-------DSAVLWLKKTQ--KAIAVTIDSN 451
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSC 566
LDP+ + + EA RN ++ GA P AI DN GDP+ PE W +
Sbjct: 452 ELYTYLDPFEGTKNVVYEAARNLISVGAKP--LAITDNLNFGDPDDPEVSWQFEKSIEGL 509
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
+ TP +SG SF N Y SI P+ +I +G + DI ++ FK G
Sbjct: 510 IEASKELSTPVVSGNVSFYNSY-----HETSIFPTPVIGMIGEIKDIKKIVNLKFKDCGD 564
Query: 627 AIYLVGKPQFS---FGGSVFAELF-GIPSGESAAVPPFKKEAAELYKKLHSNIM-----K 677
+YL+GK + GGS + ++ G GE V P +Y++ N + K
Sbjct: 565 VVYLIGKTDINVDKIGGSFYLKVLEGFVGGEIDFVNP-------MYERYLQNFILDLIDK 617
Query: 678 GLVLSCHDLSEGGLAAALYEMC-LSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIK 736
G++ S HD+S+GGL AL C LS G F L AS I LFGE G +V ++
Sbjct: 618 GILKSVHDVSKGGLLTALAVSCILSNRG------FKGILDAS-IEELFGENQGRFIVSVR 670
Query: 737 EENRSAFEKEMEGASI 752
++ FE + ++I
Sbjct: 671 SKDSRIFEDIAKSSNI 686
>gi|15805258|ref|NP_293946.1| phosphoribosylformylglycinamidine synthase II [Deinococcus
radiodurans R1]
gi|14916679|sp|Q9RXT4|PURL_DEIRA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|6457893|gb|AAF09808.1|AE001884_3 phosphoribosylformylglycinamidine synthase II [Deinococcus
radiodurans R1]
Length = 747
Score = 315 bits (808), Expect = 6e-84, Method: Composition-based stats.
Identities = 235/714 (32%), Positives = 353/714 (49%), Gaps = 97/714 (13%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K + +A+P P
Sbjct: 35 EAAIVGAMWSEHCGYKNSRPLF------------RAFP------------------TTGP 64
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
VL +NAG+++ + + V+FK E+HNHPSA+EP GA TGVGG++RD+ + ARPFA
Sbjct: 65 QVLQGPGENAGVVDIGDGWGVAFKMESHNHPSAVEPVQGAATGVGGILRDIFAMGARPFA 124
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
V D L FG+PD+P + +++GV++G+ YGN +G+PTV G V +H +Y N
Sbjct: 125 VLDSLRFGNPDSP---------RTRFLVNGVVDGIAHYGNAIGVPTVGGEVTFHPSYQEN 175
Query: 220 PLVYCGCAGIAPRGKHR-----TKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
PLV G+ +H T G+ I+ +G KTGRDGL GA FSS + A++
Sbjct: 176 PLVNVMALGLL---RHEDLATGTMGEVGNQIVYVGSKTGRDGLGGAVFSSADLSAAS-QA 231
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLA 332
+VQ+G+P ++K + E ++A GL + + D GA G S+ EMA ++LG +DL
Sbjct: 232 DRPAVQVGDPFMEKLLLEATLEAIQAGLVAGVQDMGAAGLVSSTCEMAYRASLGITMDLD 291
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
K+P + +G+ P EL LSE+QERM++ K +AL L ++++ +G R+
Sbjct: 292 KVPTREEGMVPMELCLSESQERMILVPVPGKEQALHDLLAKWELDVVTIGEVEAHDRYRL 351
Query: 393 RFGEKEIINLSCGFLHSGPPQRK-------LKAAPPKD--GKPFIKYPEYKEPDLNAALK 443
+ + + +L L+ P + ++AA +D G P DL A L
Sbjct: 352 TWKGEVVCDLPVALLNEAPKYTREGVESADIRAARERDLSGVPL-------PGDLGAVLL 404
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK----PMETEGKKAV 499
+++H + SK I YDH+V TV+ P DAAV++ PM V
Sbjct: 405 ELLSHPTIASKRPIFERYDHQVMTNTVVVPG-------AADAAVLRVKGSPM------GV 451
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
A ++ NPR LDPYA AA+A+ EA RN GA P AI DN G+P+RPE + L
Sbjct: 452 AATSDCNPRFVQLDPYAGAAAAVAEAARNLACVGATP--LAITDNLNFGNPHRPEVYYQL 509
Query: 560 IEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGS 619
+ + + TP G S N+Y + K V+I P+ I +G++PD+
Sbjct: 510 QQAVQGIADACRALNTPVTGGNVSLYNQYTEGDHK-VAIHPTPTIGMVGVLPDVTVRASL 568
Query: 620 DFKKEGSAIYLVGKP-----QFSFGGSVFAE-LFGIPSGESAAVPPFKKEAAE-LYKKLH 672
+ K G + L+G S G S + E + G+ +G+ VPP + A+ +
Sbjct: 569 NLKAAGQTLLLLGHRAEKGWSDSIGASQYLETVHGLEAGQ---VPPVDLDLAQKVVDGTL 625
Query: 673 SNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGE 726
+ I GL + HD +EGGLA AL EM ++G G L A LFGE
Sbjct: 626 ALIRAGLTDTAHDCAEGGLAVALAEMAIAG-GLGLNVSLDAPASVRADALLFGE 678
>gi|52079132|ref|YP_077923.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
licheniformis ATCC 14580]
gi|52784500|ref|YP_090329.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
licheniformis ATCC 14580]
gi|67460793|sp|Q65MS8|PURL_BACLD Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|52002343|gb|AAU22285.1| phosphoribosylformylglycinamidine synthetase II [Bacillus
licheniformis ATCC 14580]
gi|52347002|gb|AAU39636.1| PurL [Bacillus licheniformis DSM 13]
Length = 742
Score = 314 bits (804), Expect = 2e-83, Method: Composition-based stats.
Identities = 233/714 (32%), Positives = 347/714 (48%), Gaps = 75/714 (10%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K I+K + K + P +
Sbjct: 51 WSEHCSYKNSK------------------------PILKKFPTKGERVLQGPG------E 80
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP AV + L FG
Sbjct: 81 GAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIAVLNSLRFG 140
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
+P K + V+ G+ YGN +GIPTV G V + Y NPLV C
Sbjct: 141 ELTSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDGCYEGNPLVNAMCV 191
Query: 228 GIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ K G+ ++ +G KTGRDG+ GATF+S M + + S+VQ+G+P
Sbjct: 192 GLINHEDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEM-SDQSEEKRSAVQVGDPF 250
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPVKYQGLAP 343
++K + E ++ I D GA G +S+ EMAS G +++L IP + G+ P
Sbjct: 251 MEKLLLEACLEVIKSDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQRETGMTP 310
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ + + + + + D D+E +G T D +LR+ + + L
Sbjct: 311 YEMMLSESQERMLLVIERGREQEIIDIFDKYDLEAVAVGHVTDDKMLRLFHNGEMVAELP 370
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIK--YPEYKEPDLNAALKAVINHHAVNSKEDIVRLY 461
L P + P K F++ P K D L ++ + SKE + Y
Sbjct: 371 VDALAEEAPVYHKPSKVPDYYKEFLETDVPAPKVEDAKETLLELLKQPTIASKEWVYDQY 430
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASA 521
D+ V+ TV+ P DAAV++ T KKA+A++ N R LDP A
Sbjct: 431 DYMVRTNTVVAP--------GSDAAVLRIRGT--KKALAMTTDCNARYLYLDPETGGKIA 480
Query: 522 IDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGK 581
+ EA RN V +GA+P A+ DN G+P +PE W + + A V TP I G
Sbjct: 481 VAEAARNIVCSGAEP--LAVTDNLNFGNPEKPEIFWQIEKAADGISEACNVLSTPVIGGN 538
Query: 582 DSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGS 641
S NE S +I P+ +I +G++ D + FK G IY++G+ F GS
Sbjct: 539 VSLYNESNGS-----AIYPTPVIGMVGLIEDTEHITTQHFKAAGDLIYVIGETFPEFAGS 593
Query: 642 VFAELF-GIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL 700
+L G G++ A+ +++ + K L I GLV S HD+SEGG+ AL E +
Sbjct: 594 ELQKLTEGKIYGKAPAIDLEVEQSRQ--KALLKAIRSGLVQSAHDVSEGGIGVALAESVI 651
Query: 701 SG--IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASI 752
S +GA H L A + A LF ET +V +K++++ AFEK ++ A +
Sbjct: 652 SSQRLGA------HVTL-AGEPALLFSETQSRFIVSVKKDHQEAFEKLVKDADL 698
>gi|149182714|ref|ZP_01861180.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus sp.
SG-1]
gi|148849574|gb|EDL63758.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus sp.
SG-1]
Length = 743
Score = 314 bits (804), Expect = 2e-83, Method: Composition-based stats.
Identities = 232/735 (31%), Positives = 354/735 (48%), Gaps = 90/735 (12%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + K +P I VL +
Sbjct: 51 WSEHCSYKNSKPVL------------KKFP------------------ITGERVLQGPGE 80
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ ++ V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 81 GAGIVDIGDQQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFG 140
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
D+P K + V+ G+ YGN +GIPTV G V + AY NPLV C
Sbjct: 141 ELDSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDAAYEGNPLVNAMCV 191
Query: 228 GIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ + G+ ++ +G KTGRDG+ GATF+S + + + +VQ+G+P
Sbjct: 192 GLINHEDIQKGVAHGTGNTVMYIGAKTGRDGIHGATFASEELGEES-EEKRPAVQVGDPF 250
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPVKYQGLAP 343
++K + E ++ I D GA G +S+ EMAS G +++L +P + + + P
Sbjct: 251 MEKLLLEACLELVKSDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLVPQREKDMTP 310
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM+I V + ++++ D++ +GR T D LR+ G + + +
Sbjct: 311 YEMMLSESQERMLIVVEKGREAGIEEIVSKYDLDAVAIGRVTADKTLRLLHGGEIVAEVP 370
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP-----DLNAALKAVINHHAVNSKEDIV 458
L P + P ++ F ++ E + D LK +++ + SKE +
Sbjct: 371 VDALAEDAP---VYHKPSQEPAYFREFQEMEAEVPQVIDYKNTLKDLLSQPTIASKEWVY 427
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YDH+V+ TV+ P DAAVI+ T KKA+A++ N R LDP
Sbjct: 428 DQYDHQVRTNTVVSP--------GSDAAVIRIRGT--KKALAMTTDCNSRYLYLDPEMGG 477
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
A+ EA RN V +G P AI D G+P +PE W + + TP I
Sbjct: 478 KIAVVEAARNIVCSGGMP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLSTPVI 535
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
G S NE S GK ++ P+ ++ +G++ D+ + FK G IY++G + F
Sbjct: 536 GGNVSLYNE---SRGK--AVYPTPVVGMVGLIEDLSHITTQRFKAAGDLIYVIGDAREEF 590
Query: 639 GGSVF-----AELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAA 693
GGS ++FG AV ++EA L + I KG S HD++EGGLA
Sbjct: 591 GGSELQKMMNGKIFGKSPALDLAVEQQRQEA------LLNAIRKGYAASAHDIAEGGLAV 644
Query: 694 ALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGAS 751
A+ E G+GA + R+G + A LF ET +V +K+E + FE+ + A
Sbjct: 645 AMAESTFGTKGLGATI------RIGDNLTAELFSETQSRFIVSVKKEFQEQFEQTIADAK 698
Query: 752 IYEIGKTCGKAGLKL 766
+ +G+ A LK
Sbjct: 699 L--VGEVNDSAYLKF 711
>gi|134300205|ref|YP_001113701.1| phosphoribosylformylglycinamidine synthase II [Desulfotomaculum
reducens MI-1]
gi|134052905|gb|ABO50876.1| phosphoribosylformylglycinamidine synthase II [Desulfotomaculum
reducens MI-1]
Length = 741
Score = 313 bits (803), Expect = 2e-83, Method: Composition-based stats.
Identities = 238/744 (31%), Positives = 357/744 (47%), Gaps = 94/744 (12%)
Query: 37 TDAEFETI----------------AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
TD+E+E I A WSEHC +KT + + K P
Sbjct: 14 TDSEYERIVEILGRHPNYVEVGIFAVMWSEHCSYKTSRPAL------------KTLP--- 58
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+ P +L +NAGI++ + V FK E+HNHPSAIEP+ GA
Sbjct: 59 ---------------TEGPAILQGPGENAGIVDIGDGQAVVFKIESHNHPSAIEPYQGAA 103
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+ + ARP AV D L FG D P + + GV+ G+ YGN
Sbjct: 104 TGVGGILRDIFTMGARPIAVLDSLRFGELDNP---------RVRYLFDGVVSGISGYGNC 154
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLR 258
+G+PTV G V++ ++Y N LV C G+ + K G+ ++ +G KTGRDG+
Sbjct: 155 IGVPTVGGEVYFSDSYEENCLVNVMCVGLIDQKDIKKGLAAGVGNPVMVVGAKTGRDGIH 214
Query: 259 GATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAV 318
GATF+S + + + +VQ+G+P ++K + E ++ G I D GA G +S+
Sbjct: 215 GATFASEELSEAAAE-RRPAVQVGDPFMEKLLLEACLEVIKTGYVVGIQDMGAAGLTSSS 273
Query: 319 GEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDV 376
EMAS G ++DLA +P + +G+ P+EL LSE+QERM++ V + ++ + D+
Sbjct: 274 CEMASRAGTGLEMDLALVPRREEGMTPYELMLSESQERMLLVVEKGTEDKVKDIFAKWDL 333
Query: 377 ELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYP--EYK 434
+ +G+ T D +LR++ G++ + + L P P + +P +
Sbjct: 334 DCVVVGQVTDDGLLRLKEGDQVVAEMPAKALTDEAPLYHRPTEVPAYLEDIHNFPLEQLN 393
Query: 435 EP-DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMET 493
P D N L ++ + SKE + R YDH V TV+ P DAAV++ T
Sbjct: 394 MPDDYNEVLLKLLATPNIASKEYVYRQYDHMVGLNTVVLP--------GSDAAVLRVKGT 445
Query: 494 EGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRP 553
KK +A++ N R LDP AA A+ EA RN V +GA P AI + G+P +P
Sbjct: 446 --KKGIAMTTDCNGRFCYLDPKTGAAIAVAEAARNLVCSGAKP--LAITNCLNFGNPEKP 501
Query: 554 ETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDI 613
E MW V +TP G S NE S ++ P+ I +G+V D+
Sbjct: 502 EVMWTFWRCIEGMGEACRVLETPVTGGNVSLYNETKGS-----AVYPTPTIGMVGLVEDL 556
Query: 614 GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLH- 672
+V DFK EG AI+L+G+ GGS E + G P A E KK+
Sbjct: 557 DKVCTQDFKTEGDAIFLIGENLPELGGS---EYLKVHHGLEKGKAPVLDLALE--KKIQQ 611
Query: 673 ---SNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETT 728
+ I GL+ S HD SEGGLA AL E C++ G+GA++ R A LFGE+
Sbjct: 612 FVLNEIKNGLIKSAHDCSEGGLAVALAECCIAGGLGADITMVRRFR----GDALLFGESQ 667
Query: 729 GCLLVEIKEENRSAFEKEMEGASI 752
+++ + K++ A +
Sbjct: 668 SRIVISLDRSKGVELVKKLVDAGV 691
>gi|46201813|ref|ZP_00054280.2| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain [Magnetospirillum magnetotacticum
MS-1]
Length = 734
Score = 313 bits (802), Expect = 3e-83, Method: Composition-based stats.
Identities = 236/737 (32%), Positives = 366/737 (49%), Gaps = 82/737 (11%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ K +KT KA P
Sbjct: 34 ELGIFSVMWSEHCSYKSSK------------------------KWLKTLPTKA------P 63
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAGII+ + + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 64 WVICGPGENAGIIDIGDGQAIVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPIA 123
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG P P + +++GV+ G+ YGN +G+PTV G ++H +Y N
Sbjct: 124 NMNALRFGDPSHPKT---------RHLVAGVVAGIGGYGNCVGVPTVGGETNFHPSYNGN 174
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A + K + G+ ++ G KTGRDG+ GAT +S D + +
Sbjct: 175 ILVNAMTVGLADKDKIFYSAAAGIGNPVVYFGSKTGRDGIHGATMASAEFDEKSEE-KRP 233
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ AI D GA G +S+ EMAS LG ++DL +P
Sbjct: 234 TVQVGDPFTEKLLIEACLELMSTDAIVAIQDMGAAGLTSSSFEMASKGGLGIEMDLDAVP 293
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
++ +G++ +E+ LSE+QERM++ + + + + D +++ +G T + ++
Sbjct: 294 MREEGMSAYEIMLSESQERMLMVLKPGREALAKAIMDKWELDFAVVGVLTDTGRMVLKRH 353
Query: 396 EKEIINLSCGFLHSGPPQ-RKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSK 454
+ +L L P+ + AP K +P + + + + ALK ++ + SK
Sbjct: 354 GAVVADLPIDPLALASPEYDRPWTAPAK--RPVVDAKDVPQVCVAEALKTLVACPDLASK 411
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
I YDH V G TV RP DAAV++ T+ KAV I+ + PR L DP
Sbjct: 412 RWIYSQYDHMVMGDTVGRP--------GGDAAVVRIHGTD--KAVGITTDVTPRYVLADP 461
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFK 574
Y A+ EA RN A GA P AI DN G+P +PE M ++E R
Sbjct: 462 YEGGRQAVAEAYRNLSAVGALP--MAITDNLNFGNPEKPEIMGQIVEAIRGMGQACTELD 519
Query: 575 TPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKP 634
P +SG S NE ++G +I P+ + +G++ D+ + FK+ GS+I L+G+
Sbjct: 520 FPVVSGNVSLYNE---TQG--TAILPTPAVGGVGLLEDVNKSATVAFKQAGSSIVLIGET 574
Query: 635 QFSFGGSVFAELFGIPSGESAAVPPF----KKEAAELYKKLHSNIMKGLVLSCHDLSEGG 690
+ G S++ L I E A PP ++ A EL ++L I GLVL+CHD+S+GG
Sbjct: 575 KGWLGSSLY--LREIAKREDGAPPPVALHRERRAGELVRQL---IGDGLVLACHDVSDGG 629
Query: 691 LAAALYEMCLSG---IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
L A+ EM ++ IGA+L + L A FGE G ++E+ + + ++ +E
Sbjct: 630 LLVAVAEMAMASEDKIGAKLDAPHNLALH----AWCFGEDQGRYILEVSDNDLASVLEEA 685
Query: 748 --EGASIYEIGKTCGKA 762
+ IGKT G A
Sbjct: 686 AEHDTAARVIGKTGGPA 702
>gi|118466281|ref|YP_880019.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium avium
104]
gi|118167568|gb|ABK68465.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium avium
104]
Length = 765
Score = 313 bits (802), Expect = 3e-83, Method: Composition-based stats.
Identities = 235/746 (31%), Positives = 357/746 (47%), Gaps = 79/746 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E + IRE +RP TD E + WSEHC +K+ K + G + T+E +
Sbjct: 38 EYQRIREILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTTDEMRAG----- 89
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 90 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 129
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 130 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 180
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S AG+ II G +TG DG+
Sbjct: 181 LGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIG 240
Query: 259 GAT-FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSA 317
G + +S DA SVQ+G+P ++K + E ++ GL I D G G + A
Sbjct: 241 GVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLACA 300
Query: 318 VGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND 375
E+ASA G +V L +P++ G+ P E+ SE+QERM V + ++A +C D
Sbjct: 301 TSELASAGDGGMEVRLEAVPLRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWD 360
Query: 376 VELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPP-QRKLKAAPPKDGKPFIKYPEY 433
V T +G T LR+ + + ++++ + H GP QR L +D
Sbjct: 361 VLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQRPLARPDTQDALNADSSARL 420
Query: 434 KEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
P +L A L A++ + S+ I YD V+G TVL + D V++
Sbjct: 421 PRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADGGVLR 472
Query: 490 PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD 549
ET G + +A+S + R +LDPYA A A+ EA RN GA P A+ + G
Sbjct: 473 VDETTG-RGIAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCLNFGS 529
Query: 550 PNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
P P MW + R + + P G SF N+ S+ +I P+ ++ +G+
Sbjct: 530 PEDPAVMWQFAQAVRGLADGCVALGIPVTGGNVSFYNQTGSA-----AILPTPVVGVLGV 584
Query: 610 VPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE-- 666
+ D+ R+P + + G + L+G+ + F GSV+A+ + + +PP A E
Sbjct: 585 LDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQ---VTADHLGGLPPKVDLAREKL 641
Query: 667 LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKEDFHTRLGASKIASL 723
L + L + GLV + HDLSEGGLA A+ E L+G G L ED A +L
Sbjct: 642 LAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRIVLPED------ADPFVTL 695
Query: 724 FGETTGCLLVEIKEENRSAFEKEMEG 749
F E+ G +LV + S F E
Sbjct: 696 FSESAGRVLVAVPRTEESRFRSMCEA 721
Score = 69.3 bits (168), Expect = 1e-09, Method: Composition-based stats.
Identities = 80/320 (25%), Positives = 129/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ DE ++ +
Sbjct: 440 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGVLRVDETTGRGIAVSTDASGRY 491
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ PA +
Sbjct: 492 TMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQ---------FAQA 542
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+ G+ D +GIP G V ++ S P G G+ R + G
Sbjct: 543 VRGLADGCVALGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEPGE 602
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G+T RD G+ ++ + D G V + +K +AEVL A GL S
Sbjct: 603 TLMLLGET-RDEFDGSVWAQVTADHLGG--LPPKVDLAR---EKLLAEVLRAASRDGLVS 656
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + AV E +A GC + L + P+ SE+ R+++AVP
Sbjct: 657 AAHDLSEGGLAQAVVEAALAGETGCRIVLP------EDADPFVTLFSESAGRVLVAVPRT 710
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 711 EESRFRSMCEARGLPAVRIG 730
>gi|150388751|ref|YP_001318800.1| phosphoribosylformylglycinamidine synthase II [Alkaliphilus
metalliredigens QYMF]
gi|149948613|gb|ABR47141.1| phosphoribosylformylglycinamidine synthase II [Alkaliphilus
metalliredigens QYMF]
Length = 738
Score = 313 bits (801), Expect = 4e-83, Method: Composition-based stats.
Identities = 236/729 (32%), Positives = 358/729 (49%), Gaps = 72/729 (9%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R + E WSEHC +K ++ K +P
Sbjct: 24 REPNELELNLYGVMWSEHCSYKHSRSMF------------KHFP---------------- 55
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
P VL +NAGI++ + ++ K E+HNHPSAIEP+ GA TGVGG+IRD+ +
Sbjct: 56 --TSGPSVLQGPGENAGIVDIGDGLAIAMKIESHNHPSAIEPYQGAATGVGGIIRDIFAM 113
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A+ + L FG + G K ++ GV+EG+ YGN MGIPTV G V+++
Sbjct: 114 GARPIALLNSLRFGELE--------GDARVKYLLEGVVEGIAGYGNCMGIPTVGGEVYFN 165
Query: 214 EAYASNPLVYCGCAG-IAPRGKHR-TKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
++Y NPLV C G I HR T G+ I+ +G TGRDG+ GA+F+S + +
Sbjct: 166 QSYRGNPLVNAMCVGLIEHDAIHRGTASGVGNSIMYVGAATGRDGIGGASFASATLTEES 225
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDV 329
+ ++VQ+G+P ++K + E ++ G I D GA G SA E A+ G ++
Sbjct: 226 EE-KRAAVQVGDPFMEKLLLEACLELLKTGSIIGIQDLGAAGLVSACCETATRGEGGMEI 284
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
D+ K+P + G+ P E+ +SE+QERM++ V + E + ++ + +GR T D
Sbjct: 285 DVLKVPRRETGMVPVEVMISESQERMLLIVERGREEEVNEIVKKWGLHSVIIGRVTNDDK 344
Query: 390 LRVRFGEKEIINLSCGFL-HSGPPQRKLKAAPPKDGKPFIKY--PEYKEP-DLNAALKAV 445
LR+ G+K + + L SG P+ + APP D K EP DL++ L+ +
Sbjct: 345 LRIFEGDKVVGEIPAESLDSSGAPRYEPDYAPPADLAELQKLDIESIPEPRDLSSTLRKL 404
Query: 446 INHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNAL 505
+ + SKE I R YDH V+ TV++P DAAV++ T KK +A++
Sbjct: 405 LASPNIASKEWIYRQYDHMVRTNTVIKP--------GSDAAVLRIRGT--KKGIALTTDC 454
Query: 506 NPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARS 565
N R LDP + A+ EA RN V +G P AI D G P PE W E
Sbjct: 455 NSRYCYLDPREGSKIAVVEAARNIVCSGGKP--IAITDGLNFGSPETPEGYWQFRESVLG 512
Query: 566 CYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEG 625
TP ISG SF N + ++ SI P+ ++ +G++ DI + FK+ G
Sbjct: 513 LSEACREMDTPVISGNVSFYN-----QTEKGSIHPTPIVGMVGLIEDISKTCTMAFKEAG 567
Query: 626 SAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE-LYKKLHSNIMKGLVLSCH 684
I L+G+ + GGS + L I E +P + L K++ + I LV S H
Sbjct: 568 DIIVLLGQTKAEIGGSEY--LASIHGQEKGKIPHLNLSLEKRLQKEVLALIQGDLVQSAH 625
Query: 685 DLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAF 743
DLSEGGLA + E ++ GIGA ++ + R LF E+ L+ IK E+
Sbjct: 626 DLSEGGLAVGVAECAIAGGIGARVEVNTELR----NDIVLFSESQSRFLMTIKPEHLETV 681
Query: 744 EKEMEGASI 752
++ ++ ++I
Sbjct: 682 QERLKQSNI 690
>gi|41406733|ref|NP_959569.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium avium subsp. paratuberculosis K-10]
gi|67460908|sp|Q743F0|PURL_MYCPA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|41395083|gb|AAS02952.1| PurL [Mycobacterium avium subsp. paratuberculosis K-10]
Length = 765
Score = 312 bits (799), Expect = 6e-83, Method: Composition-based stats.
Identities = 234/746 (31%), Positives = 356/746 (47%), Gaps = 79/746 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E + IRE +RP TD E + WSEHC +K+ K + G + T+E +
Sbjct: 38 EYQRIREILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTTDEMRAG----- 89
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 90 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 129
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 130 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 180
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPSA-GDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S G+ II G +TG DG+
Sbjct: 181 LGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIG 240
Query: 259 GAT-FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSA 317
G + +S DA SVQ+G+P ++K + E ++ GL I D G G + A
Sbjct: 241 GVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACA 300
Query: 318 VGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND 375
E+ASA G +V L +P++ G+ P E+ SE+QERM V + ++A +C D
Sbjct: 301 TSELASAGDGGMEVRLEAVPLRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWD 360
Query: 376 VELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPP-QRKLKAAPPKDGKPFIKYPEY 433
V T +G T LR+ + + ++++ + H GP QR L +D
Sbjct: 361 VLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQRPLARPDTQDALNADSSARL 420
Query: 434 KEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
P +L A L A++ + S+ I YD V+G TVL + D V++
Sbjct: 421 PRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADGGVLR 472
Query: 490 PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD 549
ET G + +A+S + R +LDPYA A A+ EA RN GA P A+ + G
Sbjct: 473 VDETTG-RGIAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCLNFGS 529
Query: 550 PNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
P P MW + R + + P G SF N+ S+ +I P+ ++ +G+
Sbjct: 530 PEDPAVMWQFAQAVRGLADGCVALGIPVTGGNVSFYNQTGSA-----AILPTPVVGVLGV 584
Query: 610 VPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE-- 666
+ D+ R+P + + G + L+G+ + F GSV+A+ + + +PP A E
Sbjct: 585 LDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQ---VTADHLGGLPPKVDLAREKL 641
Query: 667 LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKEDFHTRLGASKIASL 723
L + L + GLV + HDLSEGGLA A+ E L+G G L ED A +L
Sbjct: 642 LAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRIVLPED------ADPFVTL 695
Query: 724 FGETTGCLLVEIKEENRSAFEKEMEG 749
F E+ G +LV + S F E
Sbjct: 696 FSESAGRVLVAVPRTEESRFRSMCEA 721
Score = 69.3 bits (168), Expect = 1e-09, Method: Composition-based stats.
Identities = 80/320 (25%), Positives = 129/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ DE ++ +
Sbjct: 440 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGVLRVDETTGRGIAVSTDASGRY 491
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ PA +
Sbjct: 492 TMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQ---------FAQA 542
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+ G+ D +GIP G V ++ S P G G+ R + G
Sbjct: 543 VRGLADGCVALGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEPGE 602
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G+T RD G+ ++ + D G V + +K +AEVL A GL S
Sbjct: 603 TLMLLGET-RDEFDGSVWAQVTADHLGG--LPPKVDLAR---EKLLAEVLRAASRDGLVS 656
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + AV E +A GC + L + P+ SE+ R+++AVP
Sbjct: 657 AAHDLSEGGLAQAVVEAALAGETGCRIVLP------EDADPFVTLFSESAGRVLVAVPRT 710
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 711 EESRFRSMCEARGLPAVRIG 730
>gi|37521682|ref|NP_925059.1| phosphoribosylformylglycinamidine synthase subunit II [Gloeobacter
violaceus PCC 7421]
gi|67460917|sp|Q7NIR9|PURL_GLOVI Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|35212680|dbj|BAC90054.1| phosphoribosylformyl glycinamidine synthetase [Gloeobacter
violaceus PCC 7421]
Length = 774
Score = 311 bits (797), Expect = 1e-82, Method: Composition-based stats.
Identities = 237/736 (32%), Positives = 348/736 (47%), Gaps = 87/736 (11%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K + + K +P P
Sbjct: 40 ELGMFSVMWSEHCCYKNSRPLL------------KGFP------------------TTGP 69
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
VL +NAG+I+ + V+FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP A
Sbjct: 70 RVLVGPGENAGVIDIGDGLRVAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIA 129
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG P A N + + GV+ G+ YGN +G+PTV G V++ Y+ N
Sbjct: 130 SLNSLRFG-PLEDARN--------RALFRGVVHGIGHYGNCVGVPTVGGEVYFDPTYSGN 180
Query: 220 PLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVM-DASTGDVAG 276
PLV G+ P G+ ++ +G TGRDG+ GA+F+S + DAS D
Sbjct: 181 PLVNAMAIGVLETPEIVRSGAAGIGNPVLYVGSTTGRDGMGGASFASAELSDASQKD--R 238
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKI 334
+VQ+G+P +K + E ++A G A D GA G + + EMA+ +G ++DL +
Sbjct: 239 PAVQVGDPFTEKSLIEACLEAFRTGAVVAAQDMGAAGLTCSSSEMAAKGGVGIEMDLDLV 298
Query: 335 PVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRF 394
PV+ G+ P+E LSE+QERM+ + L L + + +GR G+ ++R+
Sbjct: 299 PVRETGMVPYEFLLSESQERMLFVAEKGREGELIALFERWGLHAVVVGRVIGEPLVRIFH 358
Query: 395 GEKEIINLSCGFLHSGPP--QRKLKAAPPK---DGKPFIKYPEYKEPDLNAALKAVINHH 449
K + L L P R + PP + F + + D AL +++
Sbjct: 359 SGKVVAELPARALTDDAPVYPRAVLPEPPAAILKLRAFDWHSLAEPTDYAEALLTLLDSP 418
Query: 450 AVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK-------PMETEG----KKA 498
+ SK + R YDH+VQ TV+ P DAAVI+ P E E ++
Sbjct: 419 TIGSKSWVYRQYDHQVQNNTVIVPG-------AADAAVIRVRPQSFGPGEVEAVPFTERG 471
Query: 499 VAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWA 558
+A + N R LDPY A A+ EA RN GA P A+ DN G P +PE W
Sbjct: 472 IAATVDCNSRYVYLDPYRGAMLAVAEAARNLSCVGATP--LAVTDNLNFGSPEKPEGYWQ 529
Query: 559 LIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPG 618
L R + L TP G S NE S+G+ +I P+ I +G+V DI R
Sbjct: 530 LAMACRGIADACLELMTPVTGGNVSLYNE-TQSDGRTTAIYPTPTIGMVGLVEDIHRTCS 588
Query: 619 SDFKKEGSAIYLVGKPQFSFGGSVF-AELFGIPSGESAAVPPFKKEAAELYKK--LHSNI 675
+FK G +YL+G + + GGS + A L G+ +GE PP A E+ + I
Sbjct: 589 QNFKSPGDLVYLLGGGEPTLGGSEYLACLHGVAAGE----PPVLDMALEIQVQSVCRLGI 644
Query: 676 MKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIAS---LFGETTGCLL 732
+GL S HD++EGGLA AL E C++G LGA+ + FGE ++
Sbjct: 645 ERGLFKSAHDVAEGGLAVALAECCITG-----NLGLDAVLGANHPRADVVCFGEMAAAII 699
Query: 733 VEIKEENRSAFEKEME 748
V I ++ A E +E
Sbjct: 700 VTIDPCDQVACELWLE 715
>gi|152974114|ref|YP_001373631.1| phosphoribosylformylglycinamidine synthase II [Bacillus cereus
subsp. cytotoxis NVH 391-98]
gi|152022866|gb|ABS20636.1| phosphoribosylformylglycinamidine synthase II [Bacillus cereus
subsp. cytotoxis NVH 391-98]
Length = 739
Score = 310 bits (795), Expect = 2e-82, Method: Composition-based stats.
Identities = 221/670 (32%), Positives = 343/670 (51%), Gaps = 50/670 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRD+ + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDIFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + +L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPE--YKEPDLN---AALKAVINHHAV 451
+ + + L P + P K+ F ++ E K P ++ L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSKEAAYFREFQEMKMKTPKVDNYKETLLALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE KA+AI+ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KALAITTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPETGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G IY++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLIYVM 583
Query: 632 GKPQFSFGGSVFAE-LFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGG 690
G+ + FGGS + ++G G+S ++ + A+ K+L I GLV S HD++EGG
Sbjct: 584 GETKAEFGGSELQKMMYGKIFGQSPSID--LEVEAKRQKQLLEAIQAGLVQSAHDVAEGG 641
Query: 691 LAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEME 748
LA A+ E + G+GA +K L A+LF E+ +V +K E + AFEK +E
Sbjct: 642 LAVAIAESAIGAKGLGATVK------LAGEATAALFAESQSRFVVTVKREQQEAFEKVVE 695
Query: 749 GASIYEIGKT 758
+ E+ T
Sbjct: 696 AIQVGEVTNT 705
>gi|69246320|ref|ZP_00603893.1| Phosphoribosylformylglycinamidine synthase II [Enterococcus faecium
DO]
gi|68195334|gb|EAN09784.1| Phosphoribosylformylglycinamidine synthase II [Enterococcus faecium
DO]
Length = 740
Score = 310 bits (795), Expect = 2e-82, Method: Composition-based stats.
Identities = 238/721 (33%), Positives = 343/721 (47%), Gaps = 88/721 (12%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P P VL +
Sbjct: 52 WSEHCSYKNSKPVL------------RKFP------------------TSGPHVLQGPGE 81
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V FKAE+HNHPSA+EP+ GA TGVGG+IRD+ + ARP A+ D L FG
Sbjct: 82 GAGIVDIGDGLAVVFKAESHNHPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFG 141
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
D P K ++ V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 142 ELDNP---------RTKYLLEEVVAGIGGYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCV 192
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ KH K A G+ I+ +G KTGRDG+ GATF+S + + S+VQ+G+P
Sbjct: 193 GLIEH-KHIQKGQAAGVGNSIMYVGAKTGRDGIHGATFASEEFNQEE-EQQRSAVQVGDP 250
Query: 285 IIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMASALGCD--VDLAKIPVKYQG 340
++K + E ++ I D GA G S+ EMAS G + L ++P + G
Sbjct: 251 FMEKLLLEACLELILHHSDSLIGIQDMGAAGLVSSSAEMASKAGSGLILTLDEVPQRETG 310
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM+I V + + E +Q+L D++ +G+ T D R+ +E+
Sbjct: 311 MTPYEMMLSESQERMLICVKSGEEEKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVA 370
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYK----EPDLNAALKAVINHHAVNSKED 456
NL L P + P F + Y+ EP L ++ + SK
Sbjct: 371 NLPVDALAEDAPVYHKEMKEPARIVEFQQLAPYQPVIEEP--GQVLLDLLQQPTIASKRS 428
Query: 457 IVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYA 516
I YD +VQ TV+RP DAAV++ T KA+A++ N R LDP
Sbjct: 429 IYETYDSQVQTNTVVRP--------GSDAAVMRVRGT--NKALAMTTDCNARYLYLDPKI 478
Query: 517 AAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTP 576
A+ EA RN +A+G P AI D G P++PE W L A TP
Sbjct: 479 GGQIAVAEAARNIIASGGKP--LAITDCLNYGSPDKPEVFWELSTSADGIAAACETLGTP 536
Query: 577 FISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQF 636
ISG S NE ++G+ +I P+ +I +G++ D + +FKK G IY++GK
Sbjct: 537 VISGNVSLYNE---TDGQ--AIYPTPMIGMVGLIEDHKHITTQEFKKSGDLIYILGKTFA 591
Query: 637 SFGGSVFAELFGIPSGESAAVP-----PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGL 691
F GS EL + G V +K EL + + I GL+ S HD SEGGL
Sbjct: 592 DFDGS---ELQKMQLGRIEGVIRNFDLSIEKRNQEL---VLTAIQNGLIESAHDCSEGGL 645
Query: 692 AAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGAS 751
A AL E S +L L + A LF ET ++ + EN++ FE+ M A+
Sbjct: 646 AIALAE---SAFKHQLGISVQFELSS---AQLFAETQSRFVLTVAPENKTRFEEMMGDAA 699
Query: 752 I 752
+
Sbjct: 700 V 700
>gi|89101009|ref|ZP_01173852.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus sp.
NRRL B-14911]
gi|89084270|gb|EAR63428.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus sp.
NRRL B-14911]
Length = 738
Score = 310 bits (795), Expect = 2e-82, Method: Composition-based stats.
Identities = 236/739 (31%), Positives = 358/739 (48%), Gaps = 102/739 (13%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K K + K +P +
Sbjct: 43 ELGLFSVMWSEHCSYKNSKPVL------------KKFP------------------VKGE 72
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A
Sbjct: 73 RVLQGPGEGAGIVDIGDGQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIA 132
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ + L FG D+P + + V+ G+ YGN +GIPTV G V + +Y N
Sbjct: 133 LLNSLRFGELDSP---------RVRYLFKEVVAGIAGYGNCIGIPTVGGEVQFDASYEGN 183
Query: 220 PLVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
PLV C G+ K G+ ++ +G KTGRDG+ GATF+S + + +
Sbjct: 184 PLVNAMCVGLIDHKDIKKGQAHGVGNTVMYVGAKTGRDGIHGATFASEELTEQSEE-KRP 242
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIP 335
+VQ+G+P ++K + E ++ I D GA G +S+ EMAS G +++L +P
Sbjct: 243 AVQVGDPFMEKLLLEACLELVKNDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLVP 302
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ G+ +E+ LSE+QERM+I V + + + L ++E +GR T D +LR+
Sbjct: 303 QRETGMTAYEMMLSESQERMLIVVQKGREQEIVDLFSKYELEAVAIGRVTDDKMLRL--- 359
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEY------KEPDLNAA------LK 443
L G + + P L P KP + PEY E ++ AA L
Sbjct: 360 ------LHKGEVVADVPADALAEEAPVYHKP-SREPEYFREFQAMETEIPAAGNAGETLM 412
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN 503
++ + SKE + YD+ V+ TV+ P DAAV++ T +KA+A++
Sbjct: 413 RLLQQPTIASKEWVYDQYDYMVRTSTVVSP--------GSDAAVVRIRGT--RKALAMTT 462
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
N R LDP A+ EA RN +A+GA+P AI D G+P +PE W L + A
Sbjct: 463 DCNSRYLYLDPETGGKIAVAEAARNIIASGAEP--LAITDCLNFGNPEKPEIFWQLEKAA 520
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
+ L TP I G S NE + G ++ P+ ++ +G+V D+ + FK+
Sbjct: 521 DGMSSACLALNTPVIGGNVSLYNE---TNG--TAVYPTPVVGMVGLVEDVDHITTQSFKQ 575
Query: 624 EGSAIYLVGKPQFSFGGS-----VFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKG 678
G IYL+G+ + FGGS V E+FG A +KEA + L + I G
Sbjct: 576 AGDLIYLLGETKAEFGGSELQKLVHGEIFG-----KAPELDLEKEARNQEQVLKA-IRAG 629
Query: 679 LVLSCHDLSEGGLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIK 736
LV S HDL+EGGLA A E + G+GA + R+ + ++LF E+ L+ +K
Sbjct: 630 LVSSAHDLAEGGLAVAAAESVIGSEGLGALI------RISGDETSALFSESQSRFLLTVK 683
Query: 737 EENRSAFEKEMEGASIYEI 755
+E++ AFE + + E+
Sbjct: 684 KEDQQAFESMTDAILVGEV 702
>gi|116617835|ref|YP_818206.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Leuconostoc mesenteroides subsp. mesenteroides
ATCC 8293]
gi|116096682|gb|ABJ61833.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Leuconostoc mesenteroides subsp. mesenteroides
ATCC 8293]
Length = 738
Score = 310 bits (794), Expect = 3e-82, Method: Composition-based stats.
Identities = 222/668 (33%), Positives = 344/668 (51%), Gaps = 53/668 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FKAE+HNHPS +EP+ GA TGVGG++RD+ + A+P AV
Sbjct: 73 VLQGPGEGAGILDIGDNQAVVFKAESHNHPSFVEPYEGAATGVGGILRDIFSMGAQPIAV 132
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
D L FG D H K I+ GVI G+ YGN +GIPTV G + + YA NP
Sbjct: 133 LDSLRFGELDNA---------HTKHIVDGVIAGIAGYGNAIGIPTVGGEIGFDGVYAGNP 183
Query: 221 LVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV G+ + + + G+ II +G KTGRDG+ GA+F+S +S S+
Sbjct: 184 LVNVMAVGLMDQNAMQVGQAKGIGNSIIYVGAKTGRDGINGASFASAEF-SSAEKSDRSA 242
Query: 279 VQIGEPIIQKKVAEVLIDA--RDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKI 334
VQ+G+P ++K V + + A + I D GA G S+ EMA + +G ++L +
Sbjct: 243 VQVGDPFLEKLVMDATLQAIREHSDIIVGIQDMGAAGLLSSSSEMAAKAGMGIHLNLDMV 302
Query: 335 PVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRF 394
P + G+ P+EL LSE+QERMV+ V + +A+ L + D++ +G+ T D R+ F
Sbjct: 303 PQRETGMTPYELMLSESQERMVLVVKKGEEQAIIDLFQSADLDAVIIGQVTDDGRYRLNF 362
Query: 395 GEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHA---V 451
+ + ++ FL P Q L P F E EPD+ + ++ A +
Sbjct: 363 KNEVVADVPVDFLTHAPKQ-DLPMIEPARLANFTD--EQFEPDMGNVKETILTLLAQPTI 419
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SK + R +D +V+ T ++P DAA+I+ +T+ KA+A++ +N R
Sbjct: 420 ASKASLFRHFDSQVRADTAIKP--------GGDAALIRIRDTQ--KALAMTTDVNARYLY 469
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
L+P A A+ EA RN V+ GA P I D G P+ PE + L + + A
Sbjct: 470 LNPRVGAKMAVAEAARNIVSTGAKP--IGITDGLNFGSPDNPEVYYELDQAVAGINDVAK 527
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
TP ISG S NE ++G+ +I P+ +I +G++ DI + + F+K G IYLV
Sbjct: 528 QLDTPIISGNVSLYNE---TDGQ--AIYPTPMIGMVGLLEDITKATRTAFQKAGDNIYLV 582
Query: 632 GKPQFSFGGSVFAELFGIPSGESAA-VPPFKKEAAELYKKLHSNIM-KGLVLSCHDLSEG 689
G+ + SF GS E+ + +G A + F E +++ ++ + L+ S HDLSEG
Sbjct: 583 GRTKDSFNGS---EIQKMQTGHIAGQLFDFNDEDELAAQQVILDVTDQRLLNSAHDLSEG 639
Query: 690 GLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEME 748
GL L E +G +G ++ D + LF ET +V + ENR+ FE +
Sbjct: 640 GLIVGLLESAFAGNLGFDISVDLADKY-------LFSETPSRFVVSVSPENRTTFE-SLA 691
Query: 749 GASIYEIG 756
G + ++G
Sbjct: 692 GDRVIKLG 699
>gi|16077716|ref|NP_388530.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
subtilis subsp. subtilis str. 168]
gi|131646|sp|P12042|PURL_BACSU Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|143369|gb|AAA22679.1| phosphoribosylformyl glycinamidine synthetase II (PUR-Q)
gi|2632962|emb|CAB12468.1| phosphoribosylformylglycinamidine synthetase II [Bacillus subtilis
subsp. subtilis str. 168]
Length = 742
Score = 310 bits (793), Expect = 4e-82, Method: Composition-based stats.
Identities = 220/660 (33%), Positives = 334/660 (50%), Gaps = 47/660 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSA+EP+ GA TGVGG+IRDV + ARP AV
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKIESHNHPSALEPYQGAATGVGGIIRDVFSMGARPIAV 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + +Y NP
Sbjct: 134 LNSLRFGELTSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDSSYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K G+ ++ +G KTGRDG+ GATF+S M S+ + S+
Sbjct: 185 LVNAMCVGLINHEDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEMSDSS-EEKRSA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS G +++L IP
Sbjct: 244 VQVGDPFMEKLLLEACLEVIQCDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ +E+ LSE+QERM++ + + + + + D D+E ++G T D +LR+
Sbjct: 304 RETGMTAYEMMLSESQERMLLVIERGREQEIIDIFDKYDLEAVSVGHVTDDKMLRLTHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIK--YPEYKEPDLNAALKAVINHHAVNSK 454
+ + L L P + P + F++ P + D N LKA++ + SK
Sbjct: 364 EVVCELPVDALAEEAPVYHKPSQEPAYYREFLETDVPAPQIEDANEMLKALLQQPTIASK 423
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E + YD+ V+ TV+ P DA V++ T KKA+A++ N R LDP
Sbjct: 424 EWVYDQYDYMVRTNTVVAP--------GSDAGVLRIRGT--KKALAMTTDCNARYLYLDP 473
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFK 574
A+ EA RN + +GA+P A+ DN G+P +PE +W + + A V
Sbjct: 474 EVGGKIAVAEAARNIICSGAEP--LAVTDNLNFGNPEKPEILWQIEKAADGISEACNVLS 531
Query: 575 TPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKP 634
TP I G S NE S G +I P+ +I +G++ D + FK+ G +Y++G+
Sbjct: 532 TPVIGGNVSLYNE---SNG--TAIYPTPVIGMVGLIEDTAHITTQHFKQAGDLVYVIGET 586
Query: 635 QFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEGGLA 692
+ F GS EL + G P EL K L I KG V S HD+SEGGL
Sbjct: 587 KPEFAGS---ELQKMTEGRIYGKAPQIDLDVELSRQKALLDAIKKGFVQSAHDVSEGGLG 643
Query: 693 AALYE--MCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGA 750
A+ E M +GA + + + A LF E+ +V +K+E+++AFE ++ A
Sbjct: 644 VAIAESVMTTENLGANVTVE-------GEAALLFSESQSRFVVSVKKEHQAAFEATVKDA 696
>gi|89204805|ref|ZP_01183381.1| Phosphoribosylformylglycinamidine synthase II [Bacillus
weihenstephanensis KBAB4]
gi|89157432|gb|EAR77425.1| Phosphoribosylformylglycinamidine synthase II [Bacillus
weihenstephanensis KBAB4]
Length = 739
Score = 309 bits (792), Expect = 4e-82, Method: Composition-based stats.
Identities = 217/673 (32%), Positives = 341/673 (50%), Gaps = 56/673 (8%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+ +
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKD 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAV 451
+ + + L P + P K+ F ++ + K D L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSKEAAYFAEFQQMKMETPKVEDYKETLLALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ T++ P DAAVI+ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTIVTP--------GSDAAVIRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEVGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 KLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAEL-FGIPSGESAAVP---PFKKEAAELYKKLHSNIMKGLVLSCHDLS 687
G+ + FGGS ++ +G G+S ++ K++ K++ + I GLV S HD++
Sbjct: 584 GETKAEFGGSELQKMIYGKIFGQSPSIDLDVELKRQ-----KQVLAAIQAGLVQSAHDVA 638
Query: 688 EGGLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK 745
EGGLA A+ E + G+GA +K D A LF E+ ++ +K EN+ AFEK
Sbjct: 639 EGGLAVAITESAIGAKGLGATVKLD------GEATAVLFAESQSRFVITVKRENKEAFEK 692
Query: 746 EMEGASIYEIGKT 758
+E + E+ T
Sbjct: 693 AVEAIQVGEVTNT 705
>gi|17231144|ref|NP_487692.1| phosphoribosylformylglycinamidine synthase subunit II [Nostoc sp.
PCC 7120]
gi|20139488|sp|Q8YR06|PURL_ANASP Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|17132785|dbj|BAB75351.1| phosphoribosylformyl glycinamidine synthetase II [Nostoc sp. PCC
7120]
Length = 782
Score = 309 bits (791), Expect = 5e-82, Method: Composition-based stats.
Identities = 227/753 (30%), Positives = 348/753 (46%), Gaps = 101/753 (13%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P
Sbjct: 36 AELGMFGVMWSEHCCYKNSRPLL------------KQFP------------------TTG 65
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
P +L +NAG+++ E +++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 66 PRILVGPGENAGVVDLGEGLQLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 125
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
A+ + L FG + P +R+ SGV+ G+ YGN +G+PTV G V++ AY+
Sbjct: 126 ALLNSLRFGSLEDPKT---------QRLFSGVVAGISHYGNCVGVPTVGGEVYFDPAYSG 176
Query: 219 NPLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVM-DASTGDVA 275
NPLV G+ P G+ ++ +G TGRDG+ GA+F+S + D S D
Sbjct: 177 NPLVNVMALGLMETPEIVKSGAAGIGNPVLYVGSTTGRDGMGGASFASAELSDESIDD-- 234
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAK 333
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL K
Sbjct: 235 RPAVQVGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAAKGGVGIELDLDK 294
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
IPV+ + P+E LSE+QERM+ + + L + ++ G + ++R+
Sbjct: 295 IPVRETRMVPYEYLLSESQERMLFVAHQGREQELIDIFHRWGLQAVVAGTVIAEPIVRIF 354
Query: 394 FGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAA---------- 441
F + L P +R+L A PP+ + ++ P A
Sbjct: 355 FQGAIAAEIPADALAENTPLYERELLAEPPEYARLAWEWSSEALPTGTTAGIEIQGNLHS 414
Query: 442 ----LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPMETEG 495
L ++N + SK + R YDH+VQ TV P DAAV+ +P+E +G
Sbjct: 415 WQDILLTLLNTPTIASKNWVYRQYDHQVQNNTVFLPGGA-------DAAVVRLRPLEGQG 467
Query: 496 KK------------AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILD 543
+ VA + NPR LDPY A + + EA RN GA+P A+ D
Sbjct: 468 SRGAGEQGGVNSLSGVAATVDCNPRYVYLDPYEGAKAVVAEAARNLSCVGAEP--LAVTD 525
Query: 544 NFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLL 603
N G P +P W L E R TP G S NE ++G I P+ +
Sbjct: 526 NLNFGSPEKPIGYWQLSEACRGLAEGCRELATPVTGGNVSLYNETFDTQGNPQPIYPTPV 585
Query: 604 ISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP---F 660
+ +G++ D+ ++ G ++ G IYL+G + G S E A PP F
Sbjct: 586 VGMVGLIADLTKICGQGWQGVGDVIYLLGASITTLGAS---EYLATIHNTVAGRPPRVDF 642
Query: 661 KKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASK 719
E + K I G V S HD +EGGLA AL E CL+G +GAE+ H + ++
Sbjct: 643 DLE-RRVQKVCREGIHAGSVRSAHDCAEGGLAVALAESCLAGNLGAEI----HLEVSPTQ 697
Query: 720 IAS----LFGETTGCLLVEIKEENRSAFEKEME 748
+ LFGE +LV + ++ +E ++
Sbjct: 698 LQRLDEVLFGEGGARILVSVVSTQQATWESYLQ 730
>gi|124521776|ref|ZP_01696621.1| phosphoribosylformylglycinamidine synthase II [Bacillus coagulans
36D1]
gi|124496549|gb|EAY44140.1| phosphoribosylformylglycinamidine synthase II [Bacillus coagulans
36D1]
Length = 749
Score = 309 bits (791), Expect = 6e-82, Method: Composition-based stats.
Identities = 233/721 (32%), Positives = 344/721 (47%), Gaps = 89/721 (12%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K + K +P + VL
Sbjct: 48 AVMWSEHCSYKNSKPVL------------KKFP------------------VKGERVLQG 77
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AGII+ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+ + L
Sbjct: 78 PGEGAGIIDIGDGLAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSL 137
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG D+P K + V+ G+ YGN +GIPTV G V + Y NPLV
Sbjct: 138 RFGELDSP---------RVKHLFKEVVAGIAGYGNCIGIPTVGGEVAFDPCYDGNPLVNA 188
Query: 225 GCAGIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
C G+ +G+ R G+ ++ +G KTGRDG+ GATF+S + + D +V
Sbjct: 189 MCVGLIEHKDIQKGQAR---GIGNTVMYVGAKTGRDGIHGATFASGQLSEDS-DEKRPAV 244
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVK 337
Q+G+P ++K + E ++ I D GA G S+ EMAS +G ++L +IP +
Sbjct: 245 QVGDPFMEKLLLEACLELVRHDALVGIQDMGAAGLISSSSEMASKAGVGLVMNLDRIPQR 304
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
G+ P+E+ LSE+QERM+I V + + +L ++ +G T D L++ +
Sbjct: 305 ETGMTPYEMMLSESQERMLIVVKKGREPEIIRLFQKYGLDAVAIGTVTDDKRLKLYHHGE 364
Query: 398 EIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAVN 452
+ ++ L P + P K+ F Y K +L ++ +
Sbjct: 365 LVADVPADALAEDAP---VYHKPSKEPAYFAAYQVMKPQIPAVENLQETFFQLLKQPTIA 421
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
SKE + YD++V+ TV+ P DAAVI+ T +KA+A++ N R L
Sbjct: 422 SKEWVYEQYDYQVRTNTVVMP--------GSDAAVIRIRGT--RKALAMTTDCNARYVYL 471
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALV 572
DP A+ EA RN V +GA P + D G P +PE W L + A
Sbjct: 472 DPETGGKIAVAEAARNIVCSGAQP--LGVTDCLNFGAPEKPEIFWQLEKAADGMSEACRA 529
Query: 573 FKTPFISGKDSFNNEYLSSEGK-RVSIP---PSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
+TP I G S NE L G VS+ P+ ++ +G++ DI FK+ G I
Sbjct: 530 LETPVIGGNVSLYNETLQKTGNGEVSVQAVYPTPIVGMVGLLEDITHATTQTFKQAGDLI 589
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYK--KLHSNIMKGLVLSCHDL 686
YL+G+ + FGGS EL + G+ + PP E + +L + I GLV S HD+
Sbjct: 590 YLIGEAKPEFGGS---ELQKLTDGQISGKPPALDLETEARREHQLLAAIQSGLVQSAHDV 646
Query: 687 SEGGLAAALYEMCLSG---IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAF 743
SEGG A AL E CL G +GA H L + + +LF ET +V +K+E++ F
Sbjct: 647 SEGGFAPALAE-CLFGTENLGA------HVVLKGNPVTALFSETQSRFIVSVKKEHQQVF 699
Query: 744 E 744
+
Sbjct: 700 Q 700
>gi|47569938|ref|ZP_00240603.1| phosphoribosylformylglycinamidine synthase II [Bacillus cereus
G9241]
gi|47553384|gb|EAL11770.1| phosphoribosylformylglycinamidine synthase II [Bacillus cereus
G9241]
Length = 739
Score = 308 bits (790), Expect = 7e-82, Method: Composition-based stats.
Identities = 219/671 (32%), Positives = 338/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAV 451
+ + + L P + P K+ F ++ E K + L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSKEAAYFAEFQEMKMETPKVENYKETLFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEVGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ + I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMIHGKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + +G+GA +K D A+LF E+ ++ +K EN+ AFEK +
Sbjct: 641 GLAVAISESAIGANGLGATVKLD------GEATAALFAESQSRFVITVKRENKEAFEKAV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTST 705
>gi|28379218|ref|NP_786110.1| phosphoribosylformylglycinamidine synthase II [Lactobacillus
plantarum WCFS1]
gi|38258021|sp|Q88U25|PURL_LACPL Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|28272057|emb|CAD64961.1| phosphoribosylformylglycinamidine synthase II [Lactobacillus
plantarum WCFS1]
Length = 739
Score = 308 bits (789), Expect = 9e-82, Method: Composition-based stats.
Identities = 228/738 (30%), Positives = 352/738 (47%), Gaps = 76/738 (10%)
Query: 30 KTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYI 89
K +R + E + WSEHC +K K ++K +
Sbjct: 34 KVLQRLPNETETGLFSGMWSEHCSYKNSK------------------------PVLKKFW 69
Query: 90 KKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRD 149
+ ++ P + AGII+ + V FKAE+HNHPSA+EP+ GA TGVGG+IRD
Sbjct: 70 TQGEQVLEGPG------EGAGIIDIGDGQAVVFKAESHNHPSAVEPYEGAATGVGGIIRD 123
Query: 150 VMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGG 209
+ + ARP A+ D L FG P H K +IS V+ G+ YGN +GIPT+ G
Sbjct: 124 IFSMGARPIALLDSLRFGEPTDA---------HTKYLISQVVAGIGGYGNCIGIPTIGGD 174
Query: 210 VHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVM 267
+ +Y NPLV C GI + + + G+ +I +G KTGRDG+ GA+F+S
Sbjct: 175 TVFDASYQKNPLVNAMCVGILDQADIQKGQATGIGNAVIYVGAKTGRDGINGASFASAEF 234
Query: 268 DASTGDVAGSSVQIGEPIIQKKVAEVLIDA--RDQGLYSAITDCGAGGYSSAVGEMASAL 325
+ + + S+VQ+G+P ++K + E ++ + + I D GA G S+ EMAS
Sbjct: 235 NDAN-ETQRSAVQVGDPFMEKLLMEACLEVIHEHRDVLIGIQDMGAAGLVSSSAEMASKA 293
Query: 326 GC--DVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGR 383
G ++L +P + G+ P+EL LSE+QERM++ V + ++ + ++ +G+
Sbjct: 294 GSGLSLNLDLVPQRETGMTPFELMLSESQERMLLCVKAGAEAEIYQVFEKYGLDAVTIGK 353
Query: 384 FTGDAVLRVRFGEKEIINLSCGFLHS-GPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAAL 442
T ++ K + ++ L + P + K P + + D L
Sbjct: 354 VTAGHQYQLFHHGKLVADVPVDALATKAPVYEREKKRPTRLNHQSHHQFMPRLVDATGTL 413
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
K ++ + SK + YD +VQ TV++P DA VI+ T+ KA+A++
Sbjct: 414 KKMLQQPTIASKASLYGTYDSQVQTNTVVKP--------GSDAGVIRIRHTD--KALAVT 463
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
+N R L+P A+ EA RN VA+G P I D G+P +PE + L E
Sbjct: 464 TDVNGRYLYLNPRVGGEIAVAEAARNIVASGGQP--LGITDCLNYGNPEKPEQFYDLDES 521
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
A +F TP ISG S NNE S G+ +I P+ +I +G++ + SDFK
Sbjct: 522 AMGIARACQLFNTPVISGNVSLNNE---SNGE--AIYPTPMIGMVGLIKHQKDITTSDFK 576
Query: 623 KEGSAIYLVGKPQFSFGGSVFAELF-GIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVL 681
G A+Y++G + F GS ++ G SGE + + + L + I KGLV
Sbjct: 577 HAGDAVYVLGTTEADFNGSELQKMLTGTISGELFDFDLVTENRNQ--RLLLTAIQKGLVA 634
Query: 682 SCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENR 740
S HD+SEGGL + E C IG EL D A+ F ET ++ + +
Sbjct: 635 SAHDVSEGGLITTIAESCFPQNIGVELASDLPA-------ANFFAETQSRFVISVTPAQQ 687
Query: 741 SAFEKEMEGASIYEIGKT 758
+AFE ME Y +G+T
Sbjct: 688 AAFESLMEPYVTY-LGRT 704
>gi|30018537|ref|NP_830168.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
cereus ATCC 14579]
gi|67460935|sp|Q81IQ3|PURL_BACCR Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|29894077|gb|AAP07369.1| Phosphoribosylformylglycinamidine synthase [Bacillus cereus ATCC
14579]
Length = 739
Score = 308 bits (789), Expect = 9e-82, Method: Composition-based stats.
Identities = 220/671 (32%), Positives = 337/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + D+ +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYDLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPF-----IKYPEYKEPDLNAALKAVINHHAV 451
+++ + L P + P K+ F +K K + L A++ +
Sbjct: 364 EKVAEVPADALAEEAP---IYHKPSKEAAYFAEFQAMKMETPKVENYKETLFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEMGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMIHGKIFGQSPSIDLDVELKRQKQVLEAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + G+GA +K D A+LF E+ ++ +K EN+ AFEK +
Sbjct: 641 GLAVAISESAIGAKGLGATVKLD------GEATAALFAESQSRFVITVKRENKEAFEKVV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTST 705
>gi|126656683|ref|ZP_01727897.1| phosphoribosylformylglycinamidine synthase subunit II [Cyanothece
sp. CCY0110]
gi|126621903|gb|EAZ92611.1| phosphoribosylformylglycinamidine synthase subunit II [Cyanothece
sp. CCY0110]
Length = 768
Score = 308 bits (788), Expect = 1e-81, Method: Composition-based stats.
Identities = 237/752 (31%), Positives = 363/752 (48%), Gaps = 85/752 (11%)
Query: 27 EFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIK 86
E K R AE WSEHC +K + + K +P
Sbjct: 22 EIVKRLGRHPNKAELGMFGVMWSEHCCYKNSRPLL------------KNFP--------- 60
Query: 87 TYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGV 146
+ +L +NAG+++ E ++FK E+HNHPSA+EPF GA TGVGG+
Sbjct: 61 ---------TEGDRILVGPGENAGVVDLGEGLRLAFKIESHNHPSAVEPFQGAATGVGGI 111
Query: 147 IRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTV 206
+RD+ + ARP A + L FG +RI SGV+EG+ YGN +G+PTV
Sbjct: 112 LRDIFTMGARPIASLNSLRFGDLKNAKT---------RRIFSGVVEGISHYGNSVGVPTV 162
Query: 207 NGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFS 263
G ++++ AY NPLV G+ K K A G+ ++ +G TGRDG+ GA+F+
Sbjct: 163 GGEIYFNSAYNGNPLVNAMALGLM-ETKDIVKSGASGIGNPVLYVGSTTGRDGMGGASFA 221
Query: 264 SM-VMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA 322
S + D S D +VQ+G+P ++K + E ++A G A D GA G + + EMA
Sbjct: 222 SAELTDQSMDD--RPAVQVGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMA 279
Query: 323 S--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTN 380
+ +G ++DL KIPV+ G+ P+E LSE+QERM+ + + L + +++
Sbjct: 280 ANGGVGIELDLDKIPVRETGMVPYEYLLSESQERMLFVAEKGREQELIDIFHRWELQAVV 339
Query: 381 LGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPD- 437
G D ++R+ F + + L P R+L PP+ + ++ E P
Sbjct: 340 AGEVIKDPIVRILFKGEIAAEIPANALADKTPIYHRELLETPPEYAQQAWQWKEDSLPSC 399
Query: 438 ------LNAALK-------AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQD 484
+ LK +++ ++ SK+ + R YDH+VQ TV+ P D
Sbjct: 400 TPEGVKIKGELKTWDDILLTLLDTPSIASKKWVYRQYDHQVQNNTVILPGGA-------D 452
Query: 485 AAVI--KPMETEG---KKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKT 539
AAVI +P+E + K VA + N R LDP A +A+ EA RN GA+P
Sbjct: 453 AAVIRVRPIEAKPDTCKIGVAATTDCNSRYVYLDPLEGAKAAVAEAARNLSCVGAEP--L 510
Query: 540 AILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIP 599
AI +N G P P W L + KTP G S NE + ++ I
Sbjct: 511 AITNNLNFGSPENPIGYWQLALACQGISEGCRELKTPVTGGNVSLYNETVDTQQNPTPIY 570
Query: 600 PSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQF-SFGGSVF-AELFGIPSGESAAV 657
P+ +I +G++ DI +V G ++KEG IYL+G Q + GGS + A L + SG+ V
Sbjct: 571 PTPVIGMVGLIEDITKVCGQGWQKEGDIIYLLGVEQKPTLGGSEYLASLHDMVSGKPPKV 630
Query: 658 PPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLG 716
F++E + K I +G + S HD +EGGL AL E C+SG +GAE+ + +
Sbjct: 631 -DFERERL-VQKTCRDGIGQGWIKSAHDCAEGGLIIALAECCISGNLGAEISLNSAHEIR 688
Query: 717 ASKIASLFGETTGCLLVEIKEENRSAFEKEME 748
+ LFGE G ++V + EN+ +E ++
Sbjct: 689 LDTL--LFGEVCGQIIVSVSPENQQEWESYLQ 718
>gi|83590878|ref|YP_430887.1| phosphoribosylformylglycinamidine synthase II [Moorella
thermoacetica ATCC 39073]
gi|110831814|sp|Q2RGU5|PURL_MOOTA Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|83573792|gb|ABC20344.1| phosphoribosylformylglycinamidine synthase II [Moorella
thermoacetica ATCC 39073]
Length = 733
Score = 307 bits (787), Expect = 2e-81, Method: Composition-based stats.
Identities = 238/739 (32%), Positives = 365/739 (49%), Gaps = 108/739 (14%)
Query: 37 TDAEFETI----------------AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
TDAEFE + A WSEHC +K+ +
Sbjct: 12 TDAEFEKVKAILGREPNYVELGMFAVMWSEHCGYKSSR---------------------- 49
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
S++K + KA PWVL +NAGI++ + V FK E+HNHPSAIEPF GA
Sbjct: 50 --SVLKLFPTKA------PWVLQGPGENAGIVDIGDGQAVVFKIESHNHPSAIEPFQGAA 101
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+ + ARP AV + L FG P + ++ GV+ G+ YGN
Sbjct: 102 TGVGGIVRDIFAMGARPIAVLNSLRFG---------PLDDSRTRYLMGGVVGGIAFYGNC 152
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHR--TKPSAGDHIISLGGKTGRDGLR 258
+G+PTV G V++ +YA NPLV G+ + R T G+ ++ +G +TGRDG+
Sbjct: 153 LGLPTVAGEVYFEPSYACNPLVNVMAVGLIEQKNIRRGTAAGVGNAVMLIGARTGRDGIH 212
Query: 259 GATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAV 318
GATF+S + + + SVQ+G+P +K + E ++ ++ L + D GA G +S+
Sbjct: 213 GATFASEEL-SEASEERRPSVQVGDPFREKLLIEACLEIINEDLIIGMQDMGAAGITSSS 271
Query: 319 GEMA--SALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDV 376
EMA + G ++D+A +P + +G+ P+E+ LSE+QERM++ E ++ +C +
Sbjct: 272 CEMAARAGTGMEIDIALVPRREEGMTPYEVMLSESQERMLLVPKKGAEERIRAICRRWGL 331
Query: 377 ELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYK 434
E +GR TGD ++R+ + + + L P +R+ + D
Sbjct: 332 EAVIIGRVTGDGLMRIMENGRVVAEVPAKALTDQCPVYERERRRPAYLDEVRQRDLSRLP 391
Query: 435 EP-DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMET 493
EP D L ++ + SKE + R YD+ V+ TV GP G DAA+++ T
Sbjct: 392 EPEDYGRVLLGLLAAPNLASKEWVYRQYDYMVRTDTVA----GPGG----DAAILRVKGT 443
Query: 494 EGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRP 553
K +A++ N R LDP A A+ EA RN GA P AI D G+P +P
Sbjct: 444 S--KGLALTVDGNGRYCYLDPERGGAIAVAEAARNLACVGARP--LAITDCLNFGNPEKP 499
Query: 554 ETMW----ALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
E W A+ M+R+C V +TP G SF NE S +I P+ ++ +G+
Sbjct: 500 EVAWQFYQAVSGMSRACE----VLRTPVTGGNVSFYNETESG-----AIYPTPVVGMVGL 550
Query: 610 VPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELF-GIPSGESAAVPPFKKEAAELY 668
+PDI + G F++EG + L+G+ GGS + F G+ +GE A+ +++A +
Sbjct: 551 LPDIEKRCGIGFRREGDLLILMGETYPEIGGSEYLATFHGLVAGEPPALDLEREKAVQAL 610
Query: 669 KKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAE------LKEDFHTRLGASKIA 721
+ I GL + HD +EGGLA AL E L+ G+GAE L+ DF
Sbjct: 611 --VREVIAAGLATAAHDCAEGGLAVALAESALAGGLGAEVELASDLRPDF---------- 658
Query: 722 SLFGETTGCLLVEIKEENR 740
LF E+ +L+ + E R
Sbjct: 659 LLFSESQSRILLAVAPEAR 677
Score = 65.9 bits (159), Expect = 1e-08, Method: Composition-based stats.
Identities = 77/282 (27%), Positives = 121/282 (42%), Gaps = 37/282 (13%)
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
++P G V R++ V ARP A+TD L FG+P+ P + + +SG+
Sbjct: 460 LDPERGGAIAVAEAARNLACVGARPLAITDCLNFGNPEKP-----EVAWQFYQAVSGMSR 514
Query: 193 GVKDYGNKMGIPTVNGGVHYH---EAYASNPLVYCGCAGIAPRGKHRTK---PSAGDHII 246
+ + P G V ++ E+ A P G G+ P + R GD +I
Sbjct: 515 ACE----VLRTPVTGGNVSFYNETESGAIYPTPVVGMVGLLPDIEKRCGIGFRREGDLLI 570
Query: 247 SLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG---EPIIQKKVAEVLIDARDQGLY 303
+G G S + G VAG + E +Q V EV+ GL
Sbjct: 571 LMGETYPEIG------GSEYLATFHGLVAGEPPALDLEREKAVQALVREVIA----AGLA 620
Query: 304 SAITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPN 361
+A DC GG + A+ E +A LG +V+LA L P L SE+Q R+++AV
Sbjct: 621 TAAHDCAEGGLAVALAESALAGGLGAEVELA------SDLRPDFLLFSESQSRILLAVAP 674
Query: 362 DKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+ + + L V + +GR G +++ VR + + NLS
Sbjct: 675 EARDRVLDLAREKGVRASVIGRCGGHSLV-VRINGRTLFNLS 715
>gi|49479094|ref|YP_034616.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
thuringiensis serovar konkukian str. 97-27]
gi|67460817|sp|Q6HPA4|PURL_BACHK Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|49330650|gb|AAT61296.1| phosphoribosylformylglycinamidine synthase II (FGAM synthetase II)
[Bacillus thuringiensis serovar konkukian str. 97-27]
Length = 739
Score = 307 bits (787), Expect = 2e-81, Method: Composition-based stats.
Identities = 218/671 (32%), Positives = 339/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQLDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAV 451
+ + + L P + P K+ F ++ + K + L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEVGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+ +TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 MLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ + I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + +G+GA +K D A+LF E+ ++ +K EN+ AFEK +
Sbjct: 641 GLAVAISESAIGANGLGATVKLD------GEATAALFAESQSRFVITVKRENKEAFEKAV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTNT 705
>gi|30260467|ref|NP_842844.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
anthracis str. Ames]
gi|47525557|ref|YP_016906.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
anthracis str. 'Ames Ancestor']
gi|49183309|ref|YP_026561.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
anthracis str. Sterne]
gi|65317719|ref|ZP_00390678.1| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain [Bacillus anthracis str. A2012]
gi|118476045|ref|YP_893196.1| phosphoribosylformylglycinamidine synthase II [Bacillus
thuringiensis str. Al Hakam]
gi|67460937|sp|Q81ZH2|PURL_BACAN Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|30253835|gb|AAP24330.1| phosphoribosylformylglycinamidine synthase II [Bacillus anthracis
str. Ames]
gi|47500705|gb|AAT29381.1| phosphoribosylformylglycinamidine synthase II [Bacillus anthracis
str. 'Ames Ancestor']
gi|49177236|gb|AAT52612.1| phosphoribosylformylglycinamidine synthase II [Bacillus anthracis
str. Sterne]
gi|118415270|gb|ABK83689.1| phosphoribosylformylglycinamidine synthase II [Bacillus
thuringiensis str. Al Hakam]
Length = 739
Score = 307 bits (786), Expect = 2e-81, Method: Composition-based stats.
Identities = 218/671 (32%), Positives = 338/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAV 451
+ + + L P + P K+ F ++ + K + L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEVGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ + I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + +G+GA +K D A+LF E+ ++ +K EN+ AFEK +
Sbjct: 641 GLAVAISESAIGANGLGATVKLD------GEATAALFAESQSRFVITVKRENKEAFEKAV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTNT 705
>gi|75759928|ref|ZP_00739999.1| Phosphoribosylformylglycinamidine synthase [Bacillus thuringiensis
serovar israelensis ATCC 35646]
gi|74492595|gb|EAO55740.1| Phosphoribosylformylglycinamidine synthase [Bacillus thuringiensis
serovar israelensis ATCC 35646]
Length = 739
Score = 306 bits (785), Expect = 3e-81, Method: Composition-based stats.
Identities = 220/671 (32%), Positives = 337/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNGIGIPTVGGEVPFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPF-----IKYPEYKEPDLNAALKAVINHHAV 451
+++ + L P + P K+ F +K K + AL A++ +
Sbjct: 364 EKVAEVPADALAEEAP---IYHKPSKEAAYFAEFQAMKMETPKVENYKEALFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEMGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMIHGKIFGQSPSIDLDVELKRQKQVLEAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + G+GA +K D A+LF E+ ++ +K EN+ AFEK +
Sbjct: 641 GLAVAISESAIGAKGLGATVKLD------GEATAALFAESQSRFVITVKRENKEAFEKAV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTST 705
>gi|52144952|ref|YP_081878.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
cereus E33L]
gi|67460787|sp|Q63GT3|PURL_BACCZ Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|51978421|gb|AAU19971.1| phosphoribosylformylglycinamidine synthase II (FGAM synthetase II)
[Bacillus cereus E33L]
Length = 739
Score = 306 bits (783), Expect = 4e-81, Method: Composition-based stats.
Identities = 217/671 (32%), Positives = 337/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAV 451
+ + + L P + P K+ F ++ + K + L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSKEAAYFAEFQQMKMETPKIENYKETLFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEMGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ + I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMLHGKIFGQSPSIDLGVELKRQKQVLAAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + +G+GA +K D A+LF E+ ++ +K EN+ FEK +
Sbjct: 641 GLAVAISESAIGANGLGATVKLD------GEATAALFAESQSRFVITVKRENKEVFEKAV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTNT 705
>gi|144897482|emb|CAM74346.1| Phosphoribosylformylglycinamidine synthase II [Magnetospirillum
gryphiswaldense MSR-1]
Length = 732
Score = 306 bits (783), Expect = 5e-81, Method: Composition-based stats.
Identities = 240/735 (32%), Positives = 365/735 (49%), Gaps = 84/735 (11%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ K +KT KA P
Sbjct: 34 ELGIFSVMWSEHCSYKSSK------------------------KWLKTLPTKA------P 63
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAGII+ + + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 64 WVICGPGENAGIIDIGDDQAIVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPIA 123
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG P P + +++GV+ G+ YGN +G+PTV G ++H+ Y N
Sbjct: 124 NMNALRFGDPANPKT---------RHLVAGVVAGIGGYGNCVGVPTVGGETNFHKFYNGN 174
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A + + G+ ++ G KTGRDG+ GAT +S D + +
Sbjct: 175 ILVNAMTVGLADKNNIFYSAAAGVGNPVVYFGSKTGRDGIHGATMASAEFDEKSEE-KRP 233
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ + AI D GA G +S+ EMAS LG ++DL +P
Sbjct: 234 TVQVGDPFTEKLLIEACLELMATDVIVAIQDMGAAGLTSSSFEMASKGGLGVELDLDSVP 293
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF--TGDAVLRVR 393
++ +G++ +E+ LSE+QERM++ + K + + + D +++ +G TG VL+ R
Sbjct: 294 MREEGMSAYEIMLSESQERMLMILKPGKEDVARAIMDKWELDFAVIGTLTDTGRMVLK-R 352
Query: 394 FGEKEIINLSCGFLHSGPPQ-RKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVN 452
GE + NL L P+ + AP K P I + + D +ALK ++ +
Sbjct: 353 HGEI-VANLPIDPLAQASPEYDRPWTAPAK--LPVIAADKVEAVDPASALKTLLGCPDLA 409
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
SK I YDH V G TV RP DAAV++ T+ KAVAI+ PR
Sbjct: 410 SKRWIYEQYDHMVMGDTVQRP--------GGDAAVVRIHGTQ--KAVAITTDCTPRYCQA 459
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALV 572
DP+ A+ EA RN A GA P A+ DN G+P + E M ++E +
Sbjct: 460 DPHEGGRQAVAEAYRNISATGAVP--LAVTDNLNFGNPEKHEIMGQIVEAIKGMGEACRE 517
Query: 573 FKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVG 632
P +SG S NE ++G +I P+ I A+G++ D+ + FK G+ I L+G
Sbjct: 518 LDFPVVSGNVSLYNE---TQG--TAIQPTPAIGAVGLLDDVSKHMTVAFKAGGNHIVLLG 572
Query: 633 KPQFSFGGSVFAELFGIPSGESAAVPPF----KKEAAELYKKLHSNIMKGLVLSCHDLSE 688
+ + G S++ L + E A PP ++ EL ++L I G + +CHD+S+
Sbjct: 573 ETKGWLGASLY--LREVCGREEGAPPPVALHRERRKGELVRQL---IQDGQITACHDVSD 627
Query: 689 GGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSA-FEKE 746
GGL A+ EM + SGIGA L+ L A FGE G ++E+ +++ A E
Sbjct: 628 GGLLVAVAEMAMASGIGASLEAPSSLPLH----AWCFGEDQGRYVLEVGQDDLVAVLEAA 683
Query: 747 MEGASIYE-IGKTCG 760
+E + IGKT G
Sbjct: 684 LEHDCVARVIGKTGG 698
>gi|42779404|ref|NP_976651.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
cereus ATCC 10987]
gi|67460907|sp|Q73EN5|PURL_BACC1 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|42735320|gb|AAS39259.1| phosphoribosylformylglycinamidine synthase II [Bacillus cereus ATCC
10987]
Length = 739
Score = 305 bits (782), Expect = 6e-81, Method: Composition-based stats.
Identities = 217/671 (32%), Positives = 338/671 (50%), Gaps = 52/671 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVAL 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + Y NP
Sbjct: 134 LNSLRFGELQSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K AG+ ++ +G TGRDG+ GATF+S + S+ + +
Sbjct: 185 LVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESS-EAKRPA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS +G ++ L +P
Sbjct: 244 VQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ P+E+ LSE+QERM+I V + + + L + + +G+ T D +LR+
Sbjct: 304 RETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-----PDLNAALKAVINHHAV 451
+ + + L P + P ++ F ++ + K + L A++ +
Sbjct: 364 EMVAEVPADALAEEAP---IYHKPSQEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI 420
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SKE + YD++V+ TV+ P DAAV++ TE K +A++ N R
Sbjct: 421 ASKEWVYDQYDYQVRTSTVVTP--------GSDAAVVRVRGTE--KGLAMTTDCNSRYIY 470
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP A+ EA RN V +G +P AI D G+P +PE W + +
Sbjct: 471 LDPEMGGKIAVAEAARNIVCSGGEP--LAITDCLNFGNPEKPEIFWQIEKSVDGMSEACR 528
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
+TP I G S NE S E ++ P+ + +G+V D+ V +FK+ G +Y++
Sbjct: 529 TLQTPVIGGNVSMYNER-SGE----AVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVI 583
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEG 689
G+ + FGGS EL + G+ P EL K++ + I GLV S HD++EG
Sbjct: 584 GETKAEFGGS---ELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEG 640
Query: 690 GLAAALYEMCL--SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GLA A+ E + +G+GA +K D A+LF E+ ++ +K EN+ AFEK +
Sbjct: 641 GLAVAISESAIGANGLGATVKLD------GEATAALFAESQSRFVITVKRENKEAFEKAV 694
Query: 748 EGASIYEIGKT 758
E + E+ T
Sbjct: 695 EAIQVGEVTNT 705
>gi|22299226|ref|NP_682473.1| phosphoribosylformylglycinamidine synthase subunit II
[Thermosynechococcus elongatus BP-1]
gi|67460950|sp|Q8DIA7|PURL_SYNEL Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|22295408|dbj|BAC09235.1| phosphoribosylformyl glycinamidine synthetase II
[Thermosynechococcus elongatus BP-1]
Length = 761
Score = 305 bits (782), Expect = 6e-81, Method: Composition-based stats.
Identities = 230/733 (31%), Positives = 353/733 (48%), Gaps = 89/733 (12%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P
Sbjct: 36 AELGMFGVMWSEHCCYKNSRLLL------------KQFP------------------TQG 65
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
P VL +NAG+++ + ++FK E+HNHPSAIEPF GA TGVGG++RD+ + ARP
Sbjct: 66 PRVLVGPGENAGVVDLGDGLRLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPI 125
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
A+ + L FG ++++ GV+ G+ YGN +G+PTV G V++ YA
Sbjct: 126 ALLNALRFGDLKEAKT---------QQLVKGVVAGIAHYGNCVGVPTVGGEVYFDPCYAG 176
Query: 219 NPLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSM-VMDASTGDVA 275
NPLV G+ P G+ ++ +G TGRDG+ GA+F+S + D S D
Sbjct: 177 NPLVNAMALGLMETPEIVKSAASGIGNPVLYVGSTTGRDGMGGASFASAELTDESMSD-- 234
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAK 333
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL K
Sbjct: 235 RPAVQVGDPFVEKCLIEACLEAFQTGAVVAAQDMGAAGLTCSTSEMAAKGGVGIELDLDK 294
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+PV+ QG+ P+E LSE+QERM+ + L ++ ++ +GR + ++RV
Sbjct: 295 VPVREQGMVPYEFLLSESQERMLFVAAQGREAELIEIFQRWGLQAVVVGRVIAEPLVRVL 354
Query: 394 FGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYP--EYKEPDLNAA--LKAVIN 447
+ + + L P +R+ PP + ++ + P + A L ++
Sbjct: 355 YRGEVAAEVPARALAEETPLYERECPKEPPAYVQQARQWSVDQLPLPARSPAEILLTLLA 414
Query: 448 HHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNP 507
++ SK + R YDHEVQ T++ P DG DAAVI+ T K +A +
Sbjct: 415 TPSIASKAWVYRQYDHEVQNNTLVFPGDG-------DAAVIRLRGT--AKGIAATVDCPS 465
Query: 508 RQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCY 567
R LDPY +A+ EA RN GA+P A+ DN G P P W L R
Sbjct: 466 RYVYLDPYEGGKAAVAEAARNLSCVGAEP--LAVTDNLNFGSPETPVGYWQLANACRGLA 523
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
+TP G S NE + S G+ I P+ ++ +G++ D+ RV G ++ G A
Sbjct: 524 EACRALQTPVTGGNVSLYNETIDSNGQPQPIYPTPVVGMVGLIADLQRVVGQGWRATGDA 583
Query: 628 IY--------LVGKPQFSFGGSVF-AELFGIPSGESAAVPPFKKEAAELYKKLHS----N 674
IY + P+ S GGS + A++ G+ +G PP + +L +++ +
Sbjct: 584 IYLLGLPLTTPLSDPRLSLGGSEYLAQIHGLVAG----CPP--QIDLDLEQRVQAVCRYG 637
Query: 675 IMKGLVLSCHDLSEGGLAAALYEMCLSGI-GA--ELKEDFHTRLGASKIASLFGETTGCL 731
I +G + S HDLSEGGLA AL E CLSG GA +L E + R A LF E +
Sbjct: 638 IQQGWIASAHDLSEGGLAVALAESCLSGQRGATIQLPEGTYPRWD----ALLFAEGGARI 693
Query: 732 LVEIKEENRSAFE 744
LV + + A+E
Sbjct: 694 LVSVPPREQVAWE 706
>gi|113476205|ref|YP_722266.1| phosphoribosylformylglycinamidine synthase II [Trichodesmium
erythraeum IMS101]
gi|110167253|gb|ABG51793.1| phosphoribosylformylglycinamidine synthase II [Trichodesmium
erythraeum IMS101]
Length = 775
Score = 305 bits (782), Expect = 7e-81, Method: Composition-based stats.
Identities = 228/745 (30%), Positives = 351/745 (47%), Gaps = 91/745 (12%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P T K+
Sbjct: 35 AELGMFGVMWSEHCCYKNSRPLL------------KQFP---------TTGKR------- 66
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
+L +NAG+++ D +++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 67 --ILVGPGENAGVVDLDNGLQLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 124
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
AV + L FG KRI +GVI G+ YGN G+PTV G +++ AY
Sbjct: 125 AVLNSLRFGSLKDAKT---------KRIFTGVISGISHYGNCFGVPTVGGEIYFDHAYTG 175
Query: 219 NPLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
NPLV G+ P G+ ++ +G TGRDG+ GA+F+S + A + D
Sbjct: 176 NPLVNVMALGLMETPEIVKSGASGIGNPVLYVGSTTGRDGMGGASFASAELSAQSID-DR 234
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKI 334
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G + DL K+
Sbjct: 235 PAVQVGDPFLEKCLVEACLEAFKTGAVVAAQDMGAAGITCSTSEMATNGGVGIEFDLDKV 294
Query: 335 PVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRF 394
PV+ G+ P+E LSE+QERM+ + + L + ++ G + ++R+ F
Sbjct: 295 PVRETGMVPYEYLLSESQERMLFVAQKGREQELIDIFKRWELHAVVAGTVIEEPIVRILF 354
Query: 395 GEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKY-----PEYKEPDL--------- 438
K + L P R+L + PP+ + ++ P E +
Sbjct: 355 EGKVAAEIPATALADNTPIYHRELLSEPPEYVRKAWEWSVALLPASTERGIEIKGNFQTW 414
Query: 439 NAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK--------- 489
N L +++ + SK + + YD++VQ TV+ P DAAVI+
Sbjct: 415 NDILLTLLDTPTIASKNWVYQQYDYQVQNNTVIIPGGA-------DAAVIRLRSQISNIN 467
Query: 490 -PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLG 548
P+ G VA + N R LDPY A + + EA RN GA+P A+ DN G
Sbjct: 468 NPITNSG---VAATVDCNSRLVYLDPYTGAKAVVAEAARNLSCVGAEP--VAVTDNLNFG 522
Query: 549 DPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMG 608
P +P W L E R TP G S NE L ++G +I P+ ++ +G
Sbjct: 523 SPEKPVGYWQLAESCRGIAEGCRELGTPVTGGNVSLYNETLDADGHPQAIYPTPVVGMVG 582
Query: 609 IVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELY 668
+VPDI + G ++ EG IYL+G G S+ A + + A P + + +L
Sbjct: 583 LVPDITSICGQGWQTEGDVIYLIGN---LVGASLAASEYLATVHDVVAGKPIEVD-FDLE 638
Query: 669 KKLHS----NIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASL 723
+++ + I +G V S HD +EGGLA AL E C+SG +G+E+ + L
Sbjct: 639 RRVQAVCRHGIRQGWVRSAHDSAEGGLAIALAECCISGKLGSEIIWELSDFSSFRWDEFL 698
Query: 724 FGETTGCLLVEIKEENRSAFEKEME 748
FGE +LV I EN+ +E ++
Sbjct: 699 FGEGGCRILVSIAPENQIIWESYLQ 723
>gi|119493557|ref|ZP_01624222.1| Phosphoribosylformylglycinamidine synthase II [Lyngbya sp. PCC
8106]
gi|119452611|gb|EAW33793.1| Phosphoribosylformylglycinamidine synthase II [Lyngbya sp. PCC
8106]
Length = 798
Score = 304 bits (778), Expect = 2e-80, Method: Composition-based stats.
Identities = 227/754 (30%), Positives = 356/754 (47%), Gaps = 92/754 (12%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P T D
Sbjct: 38 AELGMFGVMWSEHCCYKNSRPLL------------KQFP--------------TTGD--- 68
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
+L +NAG+++F E +++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 69 -RILVGPGENAGVVDFGEGLQLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 127
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
AV + L FG D + + +GV+ G+ YGN G+PTV G V++ AY
Sbjct: 128 AVLNSLRFGSLDDA---------RTRTLFNGVVSGIAHYGNCFGVPTVGGEVYFDRAYTG 178
Query: 219 NPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
NPLV G+ + G+ ++ +G TGRDG+ GA+F+S + + +
Sbjct: 179 NPLVNAMAIGLMETSEIVKSGASGVGNPVLYVGSTTGRDGMGGASFASAELSEESIE-DR 237
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKI 334
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL KI
Sbjct: 238 PAVQVGDPFLEKSLVEACLEAFKTGAVVAAQDMGAAGITCSTAEMAAKGGVGIELDLDKI 297
Query: 335 PVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRF 394
PV+ G+ P+E LSE+QERM+ + + L + ++ G ++++R+ F
Sbjct: 298 PVRETGMVPYEYLLSESQERMLFVGKKGREQELIDIFHRWGLQAVVAGTVIEESIVRILF 357
Query: 395 GEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP--------------DL 438
+ + L P R+L A PP+ + ++ E P
Sbjct: 358 QGEIAAEIPATALADNTPIYHRELLAEPPEYARKAWEWTEDLLPPCTVSGIHVNNEFKTW 417
Query: 439 NAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEG-------NVPQDAAVIKPM 491
N L A+++ ++ SK I R YDH+VQ TV+ P G N ++ +
Sbjct: 418 NNILLALLDTPSIASKRWIYRQYDHQVQNNTVMLPGGGDAAVVRLRPVNYFENQTIENQP 477
Query: 492 ETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPN 551
+ + K+ VA + N R L+PY A + + EA RN GA+P A+ DN G P
Sbjct: 478 KVDYKRGVAATVDCNSRYVYLNPYEGAKAVVAEAARNLSCVGAEP--VAVTDNLNFGSPE 535
Query: 552 RPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVP 611
+P W L E R F TP G S NE L +EGK +I P+ +I +G+V
Sbjct: 536 KPVGYWQLAEACRGISEACGEFSTPVTGGNVSLYNETLDAEGKPQAIYPTPVIGMVGLVN 595
Query: 612 DIGRVPGSDFKKEGSAIYLVGKPQF-----------SFGGSVF-AELFGIPSGESAAVPP 659
DI + G ++ EG IYL+G QF S G S + A++ +G+ PP
Sbjct: 596 DISQTCGLAWQTEGDIIYLLGLGQFEAEEGENDARLSLGASEYLAQIHHTIAGK----PP 651
Query: 660 FKKEAAELYKKLHSNIMKGL----VLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTR 714
+ E+ +K+ + +G+ V S HD +EGGL AL E C++G GA + +
Sbjct: 652 --EVDYEIERKVQAVCREGIRQNWVNSAHDSAEGGLTIALAECCINGEKGATIHLGIDSL 709
Query: 715 LGASKIASLFGETTGCLLVEIKEENRSAFEKEME 748
L LF E +LV + E ++ +E ++
Sbjct: 710 LQRRWDRILFAEGGARILVSVSPEQQTNWENYLQ 743
>gi|126649612|ref|ZP_01721853.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus sp.
B14905]
gi|126593937|gb|EAZ87860.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus sp.
B14905]
Length = 744
Score = 303 bits (777), Expect = 3e-80, Method: Composition-based stats.
Identities = 230/730 (31%), Positives = 355/730 (48%), Gaps = 79/730 (10%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + + +P P VL +
Sbjct: 52 WSEHCSYKNSKPVL------------RKFP------------------TKGPQVLQGPGE 81
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ ++ V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP A+ + L FG
Sbjct: 82 GAGIVDIGDEQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFG 141
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
+ K + V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 142 ELKSA---------RGKYLFEEVVAGIAGYGNCIGIPTVGGEIQFDPCYEGNPLVNAMCV 192
Query: 228 GIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ + +A G+ ++ +G KTGRDG+ GATF+S + + + +VQ+G+P
Sbjct: 193 GLIDHKDIQRGIAAGVGNTVMYVGAKTGRDGIHGATFASEELTEESEN-QRPAVQVGDPF 251
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVD--LAKIPVKYQGLAP 343
++K + E ++ I D GA G +S+ EMAS G V+ L +P + G+
Sbjct: 252 MEKLLLEACLEVVKSDALVGIQDMGAAGLTSSSAEMASKAGSGVEMNLDLVPQRETGMTA 311
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ V + + ++ + D D++ +GR T D +LR+ + + +
Sbjct: 312 YEMMLSESQERMLLVVKKGREDEIKAIFDKYDLDAVAIGRVTDDKMLRLLHNGQVVAEVP 371
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP---DLNAALKAVINHHAVNSKEDIVRL 460
L P +A P F + E EP D L A++ + SKE +
Sbjct: 372 ADALAEDAPVYHKPSAEPAYYAQF-QAIENTEPAVMDYKETLNALLKAPTIASKEWVYDQ 430
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YD++V+ TV++P DAAVI+ T K +A++ N R LDP A
Sbjct: 431 YDYQVRTSTVVKP--------GSDAAVIRVRGT--NKGLAMTTDCNSRYIYLDPEVGGAI 480
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
A+ EA RN VA+G P AI D G+P +PE W + + A P I G
Sbjct: 481 AVAEAARNIVASGGTP--LAITDCLNFGNPEKPEIFWQIEKSADGISAACTALNAPVIGG 538
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
S NE S E ++ P+ I +G++ D+ V + K G ++++G+ FGG
Sbjct: 539 NVSLYNER-SGE----AVYPTPTIGMVGLIEDLAHVTTQEVKAAGDIVFVIGETTTEFGG 593
Query: 641 SVFAELF--GIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEM 698
S +L G+ SG++ A+ + EAA + L I GLV S HD++EGGLA A+ E
Sbjct: 594 SELQKLLNNGVISGKAPAI-DLEVEAAR-QQALLKAIKAGLVQSAHDVAEGGLAVAIAEK 651
Query: 699 CLS--GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIG 756
S G+G ++ L S LF E+ +V +KEE+ +AF + ++ A ++IG
Sbjct: 652 TFSANGLGVDVT------LTGSATTVLFSESQSRFVVTVKEEHAAAFVEIIKDA--HKIG 703
Query: 757 KTCGKAGLKL 766
A +K+
Sbjct: 704 VVTNDALVKI 713
>gi|54022540|ref|YP_116782.1| phosphoribosylformylglycinamidine synthase subunit II [Nocardia
farcinica IFM 10152]
gi|67460778|sp|Q5Z2C3|PURL_NOCFA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|54014048|dbj|BAD55418.1| putative phosphoribosylformylglycinamidine synthase II [Nocardia
farcinica IFM 10152]
Length = 764
Score = 303 bits (775), Expect = 3e-80, Method: Composition-based stats.
Identities = 235/755 (31%), Positives = 360/755 (47%), Gaps = 110/755 (14%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP TDAE + WSEHC +K+ K + G + TEE +K+
Sbjct: 40 RRP-TDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTEEMRKS----------------- 81
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA TGVGG++RD+M
Sbjct: 82 --------MLAGIGENAGVVDVGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMA 133
Query: 153 VSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGG 209
+ ARP AV D L FG HPDT +R++ GV+ G+ YGN +G+P V G
Sbjct: 134 MGARPVAVMDQLRFGAADHPDT------------RRVVDGVVRGIGGYGNSLGLPNVGGE 181
Query: 210 VHYHEAYASNPLVYCGCAGIAP-RGKHRTKPSA-GDHIISLGGKTGRDGLRGATFSSMVM 267
+ +Y NPLV CAG+ H S G+ II G +TG DG+ G S +
Sbjct: 182 TVFDASYQGNPLVNALCAGVMRVEDLHLAFASGTGNKIILFGARTGLDGIGGV--SVLAS 239
Query: 268 DASTGDVAGS------SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEM 321
D +GD +G+ SVQ+G+P +K + E ++ L I D G G S A E+
Sbjct: 240 DTFSGDESGAGRKKLPSVQVGDPFTEKVLIECCLELYAAKLVVGIQDLGGAGLSCATSEL 299
Query: 322 ASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELT 379
A+A G ++L K+P++ + P E+ SE+QERM V + +EA +C DV T
Sbjct: 300 AAAGDGGMRIELDKVPLRAADMTPAEILSSESQERMCAVVTPENVEAFMAVCRKWDVLAT 359
Query: 380 NLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE---- 435
+G T L V + + ++++ P R + P +P ++ P+Y++
Sbjct: 360 VIGEVTDGDRLVVTWHGETVVDV---------PPRTVAHEGPVYERP-VQRPDYQDALIA 409
Query: 436 --PD----------LNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQ 483
PD L L +I+ + S++ I YD V+G TVL
Sbjct: 410 DTPDTLPRPATADELRETLLRMISSPQLCSRKWITEQYDRYVRGNTVLAE--------DA 461
Query: 484 DAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILD 543
DA VI+ E G + +A++ + R LDPYA A A+ EA RN + GA P+
Sbjct: 462 DAGVIRIDEQTG-RGIALATDASGRYTKLDPYAGAQLALAEAFRNVASTGATPKAVTNCL 520
Query: 544 NFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLL 603
NF G P P MW + R + + P G SF N + + +I P+ +
Sbjct: 521 NF--GSPEDPGVMWQFQQAVRGLADGCVALGIPVTGGNVSFYN-----QTGQDAILPTPV 573
Query: 604 ISAMGIVPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKK 662
+ +G++ D+ R+P + G + L+G + FGGS++A++ G VPP
Sbjct: 574 VGVLGVIDDVHRRIPTGIGLEPGETLILLGDTRDEFGGSIWAQVVHDHLG---GVPPKVD 630
Query: 663 EAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKEDFHTRLGA 717
A E L + L + G++ + HDLSEGGLA A+ E L+G G L ED A
Sbjct: 631 FAREQLLAEVLTAGSRDGMISAAHDLSEGGLAQAVVEAALAGETGCRILLPED------A 684
Query: 718 SKIASLFGETTGCLLVEIKEENRSAFEKEMEGASI 752
+LF E+ G +LV + + F + E +
Sbjct: 685 DPFVTLFSESAGRVLVAVPRSEETRFTRMCEARQL 719
Score = 72.4 bits (176), Expect = 1e-10, Method: Composition-based stats.
Identities = 70/286 (24%), Positives = 120/286 (41%), Gaps = 33/286 (11%)
Query: 108 NAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
+AG+I DE+ ++ + + ++P+ GA + R+V A P AVT+ L
Sbjct: 462 DAGVIRIDEQTGRGIALATDASGRYTKLDPYAGAQLALAEAFRNVASTGATPKAVTNCLN 521
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCG 225
FG P+ P G + + G+ D +GIP G V ++ + ++
Sbjct: 522 FGSPEDP------GVMWQ---FQQAVRGLADGCVALGIPVTGGNVSFYNQTGQDAILPTP 572
Query: 226 CAGI--APRGKHRTKPSA-----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
G+ HR P+ G+ +I LG RD G+ ++ +V D G
Sbjct: 573 VVGVLGVIDDVHRRIPTGIGLEPGETLILLGDT--RDEFGGSIWAQVVHDHLGG--VPPK 628
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGE--MASALGCDVDLAKIPV 336
V ++ +AEVL G+ SA D GG + AV E +A GC + L
Sbjct: 629 VDFAR---EQLLAEVLTAGSRDGMISAAHDLSEGGLAQAVVEAALAGETGCRILLP---- 681
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
+ P+ SE+ R+++AVP + ++C+A + +G
Sbjct: 682 --EDADPFVTLFSESAGRVLVAVPRSEETRFTRMCEARQLPWVRIG 725
>gi|15607943|ref|NP_215318.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium tuberculosis H37Rv]
gi|31791991|ref|NP_854484.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium bovis AF2122/97]
gi|121636727|ref|YP_976950.1| Phosphoribosylformylglycinamidine synthase II purL [Mycobacterium
bovis BCG str. Pasteur 1173P2]
gi|148660581|ref|YP_001282104.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium tuberculosis H37Ra]
gi|148822009|ref|YP_001286763.1| phosphoribosylformylglycinamidine synthase II purL [Mycobacterium
tuberculosis F11]
gi|61230090|sp|P0A5T8|PURL_MYCTU Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|61230091|sp|P0A5T9|PURL_MYCBO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|3261789|emb|CAB09108.1| PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II PURL (FGAM SYNTHASE
II) [Mycobacterium tuberculosis H37Rv]
gi|31617578|emb|CAD93688.1| PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II PURL (FGAM SYNTHASE
II) [Mycobacterium bovis AF2122/97]
gi|121492374|emb|CAL70841.1| Phosphoribosylformylglycinamidine synthase II purL [Mycobacterium
bovis BCG str. Pasteur 1173P2]
gi|148504733|gb|ABQ72542.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium tuberculosis H37Ra]
gi|148720536|gb|ABR05161.1| phosphoribosylformylglycinamidine synthase II purL [Mycobacterium
tuberculosis F11]
Length = 754
Score = 303 bits (775), Expect = 4e-80, Method: Composition-based stats.
Identities = 230/741 (31%), Positives = 354/741 (47%), Gaps = 81/741 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R IR+ +RP TD E + WSEHC +K+ K + G + ++E + A
Sbjct: 27 EYRRIRQILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAA----- 78
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 79 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 118
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 119 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 169
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S AG+ II G +TG DG+
Sbjct: 170 LGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIG 229
Query: 259 GATFSSMVMDASTGDVAGS-----SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGG 313
G + V+ + T D GS SVQ+G+P ++K + E ++ GL I D G G
Sbjct: 230 GVS----VLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAG 285
Query: 314 YSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLC 371
S A E+ASA G + L +P++ + + P E+ SE+QERM V ++A +C
Sbjct: 286 LSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVC 345
Query: 372 DANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAP-PKDGKPFIK 429
+V T +G T L++ + + ++++ + H GP ++ A P +D +
Sbjct: 346 RKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADR 405
Query: 430 YPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDA 485
+ P +L A L A++ + S+ I YD V+G TVL + D
Sbjct: 406 SAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADG 457
Query: 486 AVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
+++ E+ G + +A+S + R LLDPYA A A+ EA RN GA P A+ +
Sbjct: 458 GMLRIDESTG-RGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCL 514
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P MW + R + P G SF N+ S+ +I P+ ++
Sbjct: 515 NFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSA-----AILPTPVVG 569
Query: 606 AMGIVPDI-GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA 664
+G++ D+ R+P + G + L+G + F GSV+A+ + + +PP A
Sbjct: 570 VLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQ---VTADHLGGLPPVVDLA 626
Query: 665 AE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIAS 722
E L L S GLV + HDLSEGGLA A+ E L+G E GA
Sbjct: 627 REKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAG---ETGCRIVLPEGADPFVL 683
Query: 723 LFGETTGCLLVEIKEENRSAF 743
LF E+ G +LV + S F
Sbjct: 684 LFSESAGRVLVAVPRTEESRF 704
Score = 73.2 bits (178), Expect = 6e-11, Method: Composition-based stats.
Identities = 80/320 (25%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ DE ++ +
Sbjct: 429 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGMLRIDESTGRGIAVSTDASGRY 480
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ P + + G+
Sbjct: 481 TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGV-----MWQFTQAVRGL 535
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+G D +GIP G V ++ S P G G+ + R G
Sbjct: 536 ADGCAD----LGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGE 591
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G T RD G+ ++ + T D G + + +K +A VL A GL S
Sbjct: 592 TLMLLGDT-RDEFDGSVWAQV-----TADHLGGLPPVVDLAREKLLAAVLSSASRDGLVS 645
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + A+ E +A GC + L +G P+ L SE+ R+++AVP
Sbjct: 646 AAHDLSEGGLAQAIVESALAGETGCRIVLP------EGADPFVLLFSESAGRVLVAVPRT 699
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 700 EESRFRGMCEARGLPAVRIG 719
>gi|15840214|ref|NP_335251.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium tuberculosis CDC1551]
gi|13880370|gb|AAK45065.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium
tuberculosis CDC1551]
Length = 754
Score = 301 bits (772), Expect = 9e-80, Method: Composition-based stats.
Identities = 229/741 (30%), Positives = 354/741 (47%), Gaps = 81/741 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R IR+ +RP TD E + WSEHC +K+ K + G + ++E + A
Sbjct: 27 EYRRIRQILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAA----- 78
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 79 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 118
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 119 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 169
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S AG+ II G +TG DG+
Sbjct: 170 LGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIG 229
Query: 259 GATFSSMVMDASTGDVAGS-----SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGG 313
G + V+ + T D GS SVQ+G+P ++K + E ++ GL I D G G
Sbjct: 230 GVS----VLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAG 285
Query: 314 YSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLC 371
S A E+ASA G + L +P++ + + P E+ SE+QERM V ++A +C
Sbjct: 286 LSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVC 345
Query: 372 DANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAP-PKDGKPFIK 429
+V T +G T L++ + + ++++ + H GP ++ A P +D +
Sbjct: 346 RKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADR 405
Query: 430 YPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDA 485
+ P +L A L A++ + S+ I YD V+G TVL + D
Sbjct: 406 SAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADG 457
Query: 486 AVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
+++ ++ G + +A+S + R LLDPYA A A+ EA RN GA P A+ +
Sbjct: 458 GMLRIDQSTG-RGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCL 514
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P MW + R + P G SF N+ S+ +I P+ ++
Sbjct: 515 NFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSA-----AILPTPVVG 569
Query: 606 AMGIVPDI-GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA 664
+G++ D+ R+P + G + L+G + F GSV+A+ + + +PP A
Sbjct: 570 VLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQ---VTADHLGGLPPVVDLA 626
Query: 665 AE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIAS 722
E L L S GLV + HDLSEGGLA A+ E L+G E GA
Sbjct: 627 REKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAG---ETGCRIVLPEGADPFVL 683
Query: 723 LFGETTGCLLVEIKEENRSAF 743
LF E+ G +LV + S F
Sbjct: 684 LFSESAGRVLVAVPRTEESRF 704
Score = 72.0 bits (175), Expect = 2e-10, Method: Composition-based stats.
Identities = 79/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ D+ ++ +
Sbjct: 429 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGMLRIDQSTGRGIAVSTDASGRY 480
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ P + + G+
Sbjct: 481 TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGV-----MWQFTQAVRGL 535
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+G D +GIP G V ++ S P G G+ + R G
Sbjct: 536 ADGCAD----LGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGE 591
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G T RD G+ ++ + T D G + + +K +A VL A GL S
Sbjct: 592 TLMLLGDT-RDEFDGSVWAQV-----TADHLGGLPPVVDLAREKLLAAVLSSASRDGLVS 645
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + A+ E +A GC + L +G P+ L SE+ R+++AVP
Sbjct: 646 AAHDLSEGGLAQAIVESALAGETGCRIVLP------EGADPFVLLFSESAGRVLVAVPRT 699
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 700 EESRFRGMCEARGLPAVRIG 719
>gi|124600175|gb|EAY59185.1| phosphoribosylformylglycinamidine synthase II purL [Mycobacterium
tuberculosis C]
Length = 767
Score = 301 bits (772), Expect = 9e-80, Method: Composition-based stats.
Identities = 229/741 (30%), Positives = 354/741 (47%), Gaps = 81/741 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R IR+ +RP TD E + WSEHC +K+ K + G + ++E + A
Sbjct: 40 EYRRIRQILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAA----- 91
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 92 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 131
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 132 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 182
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S AG+ II G +TG DG+
Sbjct: 183 LGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIG 242
Query: 259 GATFSSMVMDASTGDVAGS-----SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGG 313
G + V+ + T D GS SVQ+G+P ++K + E ++ GL I D G G
Sbjct: 243 GVS----VLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAG 298
Query: 314 YSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLC 371
S A E+ASA G + L +P++ + + P E+ SE+QERM V ++A +C
Sbjct: 299 LSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVC 358
Query: 372 DANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAP-PKDGKPFIK 429
+V T +G T L++ + + ++++ + H GP ++ A P +D +
Sbjct: 359 RKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADR 418
Query: 430 YPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDA 485
+ P +L A L A++ + S+ I YD V+G TVL + D
Sbjct: 419 SAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADG 470
Query: 486 AVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
+++ ++ G + +A+S + R LLDPYA A A+ EA RN GA P A+ +
Sbjct: 471 GMLRIDQSTG-RGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCL 527
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P MW + R + P G SF N+ S+ +I P+ ++
Sbjct: 528 NFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSA-----AILPTPVVG 582
Query: 606 AMGIVPDI-GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA 664
+G++ D+ R+P + G + L+G + F GSV+A+ + + +PP A
Sbjct: 583 VLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQ---VTADHLGGLPPVVDLA 639
Query: 665 AE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIAS 722
E L L S GLV + HDLSEGGLA A+ E L+G E GA
Sbjct: 640 REKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAG---ETGCRIVLPEGADPFVL 696
Query: 723 LFGETTGCLLVEIKEENRSAF 743
LF E+ G +LV + S F
Sbjct: 697 LFSESAGRVLVAVPRTEESRF 717
Score = 72.0 bits (175), Expect = 2e-10, Method: Composition-based stats.
Identities = 79/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ D+ ++ +
Sbjct: 442 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGMLRIDQSTGRGIAVSTDASGRY 493
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ P + + G+
Sbjct: 494 TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGV-----MWQFTQAVRGL 548
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+G D +GIP G V ++ S P G G+ + R G
Sbjct: 549 ADGCAD----LGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGE 604
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G T RD G+ ++ + T D G + + +K +A VL A GL S
Sbjct: 605 TLMLLGDT-RDEFDGSVWAQV-----TADHLGGLPPVVDLAREKLLAAVLSSASRDGLVS 658
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + A+ E +A GC + L +G P+ L SE+ R+++AVP
Sbjct: 659 AAHDLSEGGLAQAIVESALAGETGCRIVLP------EGADPFVLLFSESAGRVLVAVPRT 712
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 713 EESRFRGMCEARGLPAVRIG 732
>gi|25009003|sp|Q8PYK1|PURL_METMA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
Length = 716
Score = 301 bits (771), Expect = 1e-79, Method: Composition-based stats.
Identities = 220/678 (32%), Positives = 326/678 (48%), Gaps = 77/678 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +++ ++KT+ + I P D
Sbjct: 30 WSEHCSYRSSAP------------------------LLKTFTTTGENVIIGPG------D 59
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
+A II+F++ Y ++ E+HNHPS ++P+ GA TGVGG++RD++ + ARP A+ D L FG
Sbjct: 60 DAAIIKFEDGYVLAIGMESHNHPSYVDPYNGAATGVGGIVRDIISMGARPIALMDPLYFG 119
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP + +I+G+ YGN +G+P VNG + Y+ NPLV
Sbjct: 120 PLDTPKNLF---------LFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPLVNVVAV 170
Query: 228 GIAPRGKHRTKPS--AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ K T S AG+ +I G TG+DGL GA+F+S + S SVQ+G+P
Sbjct: 171 GLCKEEKVMTSRSQKAGNKLILAGSSTGKDGLGGASFASRDLSESAEAEDRPSVQVGDPY 230
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
+K V E+ ++A D+G + D GA G A E+A+ LG + +P + +
Sbjct: 231 TEKLVMEMTLEAIDKGYIKSCKDLGAAGLGGASSELAAKGGLGAYIIADAVPQREPEMNA 290
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ L+E+QERMV V + ++A+ L D+ +G T V F + + ++
Sbjct: 291 YEILLAESQERMVFEVAPEDVDAVLALVQKYDLNGAVIGHLTEKPNYTVEFRGEIVADIP 350
Query: 404 CGFLHSGPPQRKLKAAPP---KDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRL 460
GFL G P + + P ++GK PE E DL AA V++ H + SKE I R
Sbjct: 351 IGFLTGGAPTCEKPSEAPIHREEGKK----PETPE-DLKAAFMKVLSSHNIASKEWIYRQ 405
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YDHEVQ TV++P +D+ V++ + KK +A+S PR LLDPY +
Sbjct: 406 YDHEVQLRTVVKP--------GEDSGVLRITD---KKGIALSCGCQPRATLLDPYTGGRT 454
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
AI E N GA E AI++ G+P PET W + A P + G
Sbjct: 455 AIIENAMNLAVKGA--EGLAIVNCLNFGNPENPETYWQFKNAVLGLGDAARELSIPVVGG 512
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
S NE S+ R +IPP+ I +G V +P F K G +I LVG+ GG
Sbjct: 513 NVSLYNE---SDEFRTAIPPTPSIGMIGKVDLETPLPSGFFAKTGDSIILVGETVPEMGG 569
Query: 641 SVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC- 699
S + G +G + VP K A E+ K + + G + S HD+S GG+ A L MC
Sbjct: 570 SEYYSCMG--AGNAGKVPEVPKNAPEIIKAVIEAVKSGKLNSAHDISLGGIGAGLARMCK 627
Query: 700 -------LSGIGAELKED 710
+S I +KED
Sbjct: 628 NMGGKVDVSEIAGGMKED 645
>gi|81255344|ref|ZP_00879826.1| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain [Mycobacterium tuberculosis C]
Length = 766
Score = 301 bits (771), Expect = 1e-79, Method: Composition-based stats.
Identities = 229/741 (30%), Positives = 354/741 (47%), Gaps = 81/741 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R IR+ +RP TD E + WSEHC +K+ K + G + ++E + A
Sbjct: 39 EYRRIRQILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAA----- 90
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 91 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 130
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 131 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 181
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S AG+ II G +TG DG+
Sbjct: 182 LGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIG 241
Query: 259 GATFSSMVMDASTGDVAGS-----SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGG 313
G + V+ + T D GS SVQ+G+P ++K + E ++ GL I D G G
Sbjct: 242 GVS----VLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAG 297
Query: 314 YSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLC 371
S A E+ASA G + L +P++ + + P E+ SE+QERM V ++A +C
Sbjct: 298 LSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVC 357
Query: 372 DANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAP-PKDGKPFIK 429
+V T +G T L++ + + ++++ + H GP ++ A P +D +
Sbjct: 358 RKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADR 417
Query: 430 YPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDA 485
+ P +L A L A++ + S+ I YD V+G TVL + D
Sbjct: 418 SAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADG 469
Query: 486 AVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
+++ ++ G + +A+S + R LLDPYA A A+ EA RN GA P A+ +
Sbjct: 470 GMLRIDQSTG-RGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCL 526
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P MW + R + P G SF N+ S+ +I P+ ++
Sbjct: 527 NFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSA-----AILPTPVVG 581
Query: 606 AMGIVPDI-GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA 664
+G++ D+ R+P + G + L+G + F GSV+A+ + + +PP A
Sbjct: 582 VLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQ---VTADHLGGLPPVVDLA 638
Query: 665 AE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIAS 722
E L L S GLV + HDLSEGGLA A+ E L+G E GA
Sbjct: 639 REKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAG---ETGCRIVLPEGADPFVL 695
Query: 723 LFGETTGCLLVEIKEENRSAF 743
LF E+ G +LV + S F
Sbjct: 696 LFSESAGRVLVAVPRTEESRF 716
Score = 72.0 bits (175), Expect = 2e-10, Method: Composition-based stats.
Identities = 79/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ D+ ++ +
Sbjct: 441 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGMLRIDQSTGRGIAVSTDASGRY 492
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ P + + G+
Sbjct: 493 TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGV-----MWQFTQAVRGL 547
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+G D +GIP G V ++ S P G G+ + R G
Sbjct: 548 ADGCAD----LGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGE 603
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G T RD G+ ++ + T D G + + +K +A VL A GL S
Sbjct: 604 TLMLLGDT-RDEFDGSVWAQV-----TADHLGGLPPVVDLAREKLLAAVLSSASRDGLVS 657
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + A+ E +A GC + L +G P+ L SE+ R+++AVP
Sbjct: 658 AAHDLSEGGLAQAIVESALAGETGCRIVLP------EGADPFVLLFSESAGRVLVAVPRT 711
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 712 EESRFRGMCEARGLPAVRIG 731
>gi|146297001|ref|YP_001180772.1| phosphoribosylformylglycinamidine synthase II [Caldicellulosiruptor
saccharolyticus DSM 8903]
gi|145410577|gb|ABP67581.1| phosphoribosylformylglycinamidine synthase II [Caldicellulosiruptor
saccharolyticus DSM 8903]
Length = 730
Score = 301 bits (770), Expect = 1e-79, Method: Composition-based stats.
Identities = 231/743 (31%), Positives = 349/743 (46%), Gaps = 85/743 (11%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R + E WSEHC +K KA ++K K
Sbjct: 25 REPNELELNLFGVMWSEHCGYKNSKA------------------------LLKQLPTKGE 60
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
+ P +NAGI++ + Y V FK E+HNHPSA+EP+ GA TGVGG+IRD+ +
Sbjct: 61 HILQGPG------ENAGIVDIGDGYAVCFKVESHNHPSAVEPYEGAATGVGGIIRDIFTM 114
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A+ D L FG + K + GV+ G+ YGN +GIPTV G +
Sbjct: 115 GARPIALLDSLKFGKLEDS---------RTKYLFEGVVSGIAGYGNCVGIPTVGGETTFD 165
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
Y +N L+ C GI + K G+ + +G TGRDG+ GATF+S + +
Sbjct: 166 PIYKNNILINVMCVGIMKKDKIFKGVAQGVGNSVFYVGHTTGRDGMGGATFASADLTQES 225
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDV 329
+ S+VQ+G+P ++K + E ++ I D GA G +S+ E A + G ++
Sbjct: 226 EE-KRSAVQVGDPFMEKLLLEACLELFQTDAVVGIQDMGAAGLTSSTCETAARAGTGIEI 284
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
D+A +P + +G+ P E+ LSE+QERM++ V +K E + K+ + + +GR T D +
Sbjct: 285 DVALVPKREEGMNPIEVMLSESQERMLVIVKKEKEEEVYKIFEKWGLHAVKIGRVTDDGM 344
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPP--KDGKPFIKYPEYKEPDLNAALKAVIN 447
LR+ + + L P + P K + F Y + DLN A+ +I+
Sbjct: 345 LRILDNGNVVAEVPAKALAHAPAYVRKTKEPEIVKISQQFDIYSLPQPQDLNEAILKMIS 404
Query: 448 HHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNP 507
+ + SKE I R YD+ V+ TV+R + DA++++ T KK +A++ N
Sbjct: 405 NPNLASKEYIYRQYDYMVRTDTVIR--------LGHDASLLRVKGT--KKGIAVTIDSNG 454
Query: 508 RQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCY 567
R L+PY + E+ RN VA GA P AI D G+P PE + ++
Sbjct: 455 RYCYLNPYEGVQLVLAESYRNIVAVGAKP--LAITDGLNFGNPLYPEIYYQFVKTIEGLK 512
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
F TP G SF N+ S EG +I P+ +I +G++ D+G+ FK+EG
Sbjct: 513 VACEYFGTPVTGGNVSFYNQ--SEEG---AIYPTPVIGMVGVIEDVGKAVDISFKEEGDV 567
Query: 628 IYLVGKPQFSFGGSVFAELF-GIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHD 685
I ++GK G S + + G+ SG VP K E K+ I +GL S HD
Sbjct: 568 IAIIGKTLDDIGASEYLSFYHGVVSGR---VPKLDLKRHRETCDKVLECINQGLFKSVHD 624
Query: 686 LSEGGLAAALYEMCLSG-------IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEE 738
+S+GG AL E G + L+EDF+ LF ET G LV KEE
Sbjct: 625 ISDGGFIIALLESAFRGKKGAAIKVNTSLREDFY----------LFSETPGRFLVTFKEE 674
Query: 739 NRSAFEKEMEGASIYEIGKTCGK 761
N + + G + +G+ K
Sbjct: 675 NLPKIREILNGIELEIVGEVTDK 697
>gi|120406067|ref|YP_955896.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium
vanbaalenii PYR-1]
gi|119958885|gb|ABM15890.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium
vanbaalenii PYR-1]
Length = 764
Score = 301 bits (770), Expect = 2e-79, Method: Composition-based stats.
Identities = 231/756 (30%), Positives = 354/756 (46%), Gaps = 80/756 (10%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
R L E IRE +RP TDAE + WSEHC +K+ K + G + TE+
Sbjct: 22 RELGLKDDEYERIREILG--RRP-TDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTEKM 78
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
++ +L+ +NAG+++ + + +FK E+HNHPS
Sbjct: 79 RET-------------------------MLAGIGENAGVVDIGDGWAATFKVESHNHPSY 113
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
IEP+ GA TGVGG++RD+M + ARP AV D L FG D P +R++ GV+
Sbjct: 114 IEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVR 164
Query: 193 GVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG--KHRTKPSAGDHIISLGG 250
G+ YGN +G+P + G + +YA NPLV C G+ + K AG+ II G
Sbjct: 165 GIGGYGNSLGLPNIGGETVFDASYAGNPLVNALCVGVLRKEDLKLAFASGAGNKIILFGA 224
Query: 251 KTGRDGLRGATFSSMVMDASTGDVAGS------SVQIGEPIIQKKVAEVLIDARDQGLYS 304
+TG DG+ G S + + GD +G+ SVQ+G+P +K + E ++ L
Sbjct: 225 RTGLDGIGGV--SVLASETFGGDESGAGRKKLPSVQVGDPFTEKVLIECCLELYAADLVV 282
Query: 305 AITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
I D G G S A E+ASA G V+L ++P++ + P E+ SE+QERM V D
Sbjct: 283 GIQDLGGAGLSCATSELASAGDGGMRVELERVPLRAANMTPAEILSSESQERMCAVVTPD 342
Query: 363 KLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPP-QRKLKAAP 420
++A +C DV T++G T L + + + ++++ + H GP +R ++
Sbjct: 343 NVDAFMAVCRKWDVLATDIGEVTDSGRLEITWHGETVVDVPPRTVAHEGPVYERPVQRPD 402
Query: 421 PKDGKPFIKYPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDG 476
+D + P +L A L ++ A+ S+ I YD V+G TVL +
Sbjct: 403 SQDALVANTTASLERPSTGDELRATLLQLLGSPALCSRAFITEQYDRYVRGNTVLAEH-- 460
Query: 477 PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADP 536
D V++ E G + +AIS + R LDPYA A A+ EA RN GA P
Sbjct: 461 ------ADGGVLRVDEQTG-RGIAISTDASGRYTALDPYAGAQLALAEAYRNVAVTGATP 513
Query: 537 EKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRV 596
A+ + G P P MW + R + A P G SF N+ ++
Sbjct: 514 --VAVTNCLNFGSPEDPGVMWQFSQAVRGLADGAAALGIPVTGGNVSFYNQTGTT----- 566
Query: 597 SIPPSLLISAMGIVPDIGRVPGSDFKKE-GSAIYLVGKPQFSFGGSVFAELFGIPSGESA 655
+I P+ ++ +G++ D+ R + F E G + L+G + F GS++A+ + +
Sbjct: 567 AILPTPVVGVLGVIDDVKRRIPTGFGTEPGETLILLGDTRDEFDGSIWAQ---VTADHLG 623
Query: 656 AVPPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHT 713
VPP E L + L + GLV + HDLSEGGL A+ E L+G E
Sbjct: 624 GVPPTVDLDRERLLAEVLTAASRDGLVSAAHDLSEGGLIQAVVEASLAG---ETGCRIVL 680
Query: 714 RLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
G + +LF E+ G +LV + S F E
Sbjct: 681 PEGWNPFVTLFSESAGRVLVAVPRTEESRFTAMCEA 716
Score = 77.4 bits (189), Expect = 4e-12, Method: Composition-based stats.
Identities = 84/323 (26%), Positives = 135/323 (41%), Gaps = 49/323 (15%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ DE+ ++ +
Sbjct: 435 PALCSRAFITEQYDRYVRGNT-------VLAEHAD-GGVLRVDEQTGRGIAISTDASGRY 486
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+A++P+ GA + R+V A P AVT+ L FG P+ P G + S
Sbjct: 487 TALDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDP------GVMWQ---FSQA 537
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHR------TKPSA 241
+ G+ D +GIP G V ++ + P G G+ K R T+P
Sbjct: 538 VRGLADGAAALGIPVTGGNVSFYNQTGTTAILPTPVVGVLGVIDDVKRRIPTGFGTEP-- 595
Query: 242 GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQG 301
G+ +I LG RD G+ ++ + D G +V + ++ +AEVL A G
Sbjct: 596 GETLILLGDT--RDEFDGSIWAQVTADHLGG--VPPTVDLDR---ERLLAEVLTAASRDG 648
Query: 302 LYSAITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAV 359
L SA D GG AV E +A GC + L +G P+ SE+ R+++AV
Sbjct: 649 LVSAAHDLSEGGLIQAVVEASLAGETGCRIVLP------EGWNPFVTLFSESAGRVLVAV 702
Query: 360 PNDKLEALQKLCDANDVELTNLG 382
P + +C+A + +G
Sbjct: 703 PRTEESRFTAMCEARGLPANRIG 725
>gi|20093935|ref|NP_613782.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Methanopyrus kandleri AV19]
gi|22096007|sp|Q8TY09|PURL_METKA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|19886885|gb|AAM01712.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Methanopyrus kandleri AV19]
Length = 724
Score = 301 bits (770), Expect = 2e-79, Method: Composition-based stats.
Identities = 220/707 (31%), Positives = 357/707 (50%), Gaps = 86/707 (12%)
Query: 17 LDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAY 76
LD ++ IRE + A FE + WSEHC +++ T +
Sbjct: 3 LDERDLELIREELGRDPNATERAMFENM---WSEHCAYRS------------TRHLLRQL 47
Query: 77 PGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPF 136
P +A V+ D+A ++ D+++ V E+HNHPS ++P+
Sbjct: 48 PS------------------EADHVIVGPGDDAAVVAIDDEWAVVVGIESHNHPSYVDPY 89
Query: 137 GGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKD 196
GA TGVGG++RDV+ + A P A+ D L FG D E VP ++ GV+ G+ D
Sbjct: 90 NGAATGVGGIVRDVLSMGAFPIALLDPLRFGPLD--GERVP-------YLVDGVVRGISD 140
Query: 197 YGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGR 254
YGN++G+PTV G + + +Y NPLV C GI R + GD ++ +G +TGR
Sbjct: 141 YGNRIGVPTVGGELEFDPSYERNPLVNVMCVGIVRRSEIVRGRADRPGDVLVLVGARTGR 200
Query: 255 DGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGY 314
DG+ GA F+S + + + +VQIG+P ++++ + +A ++GL D GA G
Sbjct: 201 DGIGGAAFASEELGEESEEEDRPAVQIGDPFTERQLIIAIREAVERGLVKGCKDLGAAGL 260
Query: 315 SSAVGEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCD 372
+ A EMA+ G ++D+ K+P++ +G+ PWE+ LSE+QERM++ V + ++ + ++C
Sbjct: 261 TCAATEMAADGGTGVEIDVFKVPLREEGMEPWEIMLSESQERMLLVVAPEDVDEVIEICR 320
Query: 373 ANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPE 432
+E + +GR T D L V+ G+ I + FL G P+ + + P YPE
Sbjct: 321 KYGLEASVVGRVTDDGYLTVKDGDDVIARVPAEFLADGAPEVEWEEEP-------YSYPE 373
Query: 433 ---YKEPDLNAALKAVINHHAVNS--KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAV 487
EPD +++V++ V+ +E + R YDHEVQG TV++P DAAV
Sbjct: 374 NVDVPEPDPEDLVRSVLSSPNVSPALREWVYRQYDHEVQGRTVVKP--------GHDAAV 425
Query: 488 IKPMETEGKK--AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
+ ++ EG + A+A++ NPR L+DP + EA+RN GA+P ++D
Sbjct: 426 MW-LQHEGLEDVALALTTDSNPRHVLIDPKTGTEGCVAEALRNLATVGAEP--LCLVDCL 482
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P + L A F+ P + G S NE+ +G + P+ +I
Sbjct: 483 NFGSPENPRVYYQLRRSIEGLGKAAREFEVPVVGGNVSLYNEH-EVDG---PVNPTPVIG 538
Query: 606 AMGIVPDIGRVPGSDFKK---EGSAIYLVGKPQFSFGGSVF-AELFGIPSGESAAVPPFK 661
A+G++ + + DF + EG A+ ++G+ + GGS++ E GI G+ VP +
Sbjct: 539 AVGVIRGLDYL--EDFPREPEEGEAVIVLGETREELGGSLYLIEYHGIKGGK---VPRVR 593
Query: 662 -KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAEL 707
+E L+ L K +V S D+S GGL AA+ E+ L +GA L
Sbjct: 594 YREERALHDLLRRIARKNMVSSVTDVSTGGLLAAVAEL-LGPVGASL 639
Score = 65.5 bits (158), Expect = 1e-08, Method: Composition-based stats.
Identities = 73/295 (24%), Positives = 130/295 (44%), Gaps = 38/295 (12%)
Query: 119 EVSFKAETHNHPS--AIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENV 176
+V+ T ++P I+P G V +R++ V A P + D L FG P+ P
Sbjct: 435 DVALALTTDSNPRHVLIDPKTGTEGCVAEALRNLATVGAEPLCLVDCLNFGSPENP---- 490
Query: 177 PKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAY----ASNPLVYCGCAGIAPR 232
+ +R I G+ + +++ +P V G V + + NP G G+ R
Sbjct: 491 -RVYYQLRRSIEGLGKAAREFE----VPVVGGNVSLYNEHEVDGPVNPTPVIGAVGVI-R 544
Query: 233 G-----KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQ 287
G +P G+ +I LG R+ L G+ + G V V+ E +
Sbjct: 545 GLDYLEDFPREPEEGEAVIVLG--ETREELGGSLYLIEYHGIKGGKVP--RVRYRE---E 597
Query: 288 KKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWE-L 346
+ + ++L + + S++TD GG +AV E+ +G + L+++P ++ W+ L
Sbjct: 598 RALHDLLRRIARKNMVSSVTDVSTGGLLAAVAELLGPVGASLSLSEVP---NSVSRWDFL 654
Query: 347 WLSEAQERMVIAV--PNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEI 399
LSE+ R ++ P+D L A ++ V +G TGD VLR+ G ++
Sbjct: 655 LLSESHGRAIVTTDRPDDVLGAAEEA----GVPAQVVGEVTGDGVLRISVGPVDV 705
>gi|156938039|ref|YP_001435835.1| phosphoribosylformylglycinamidine synthase II [Ignicoccus
hospitalis KIN4/I]
gi|156567023|gb|ABU82428.1| phosphoribosylformylglycinamidine synthase II [Ignicoccus
hospitalis KIN4/I]
Length = 713
Score = 300 bits (769), Expect = 2e-79, Method: Composition-based stats.
Identities = 225/726 (30%), Positives = 369/726 (50%), Gaps = 77/726 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E++ I E T R E WSEHC +K+
Sbjct: 7 ELKLIEE---TLGRKPNQVELAMFEAQWSEHCSYKS------------------------ 39
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+ +++K +D+PWV+ +A +++F Y V+F+ E+HNHPSA++P+ GA
Sbjct: 40 ----SRKHLRKLK--MDSPWVVKG--GDAAVVDFGSVY-VAFRIESHNHPSAVDPYNGAA 90
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG+IRD++ A+P A+ D L FG D EN+ K + GV++G+ DYGN+
Sbjct: 91 TGVGGIIRDILSSGAKPIALLDDLIFGDLD---ENLVKWH------VKGVVKGISDYGNR 141
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKH-RTKPSAGDHIISLGGKTGRDGLRG 259
+G+PTV G + + NP+V C G+ P+ K P GD I+ G TG+DGL G
Sbjct: 142 VGVPTVGGETWFDPDFTRNPMVSVACVGVCPKDKLINGTPRPGDLIVIAGNYTGKDGLLG 201
Query: 260 ATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVG 319
++F+S ++ + +++Q+ +P+++K + + +++ RD+ L + D G GG ++A+
Sbjct: 202 SSFASKNLEEGVEE-EYAAIQVPDPLMEKLLIDSILEMRDERLLVFVKDLGGGGLATALS 260
Query: 320 EMASALGCDVDLAKIPVKY--QGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVE 377
E+A++ G V+ A++ + + + WE+ +SE+QERM++ + + LE +K+ + DV
Sbjct: 261 EVAASFGLGVE-ARLDALHLREPMEAWEIVVSESQERMMLVIRPEDLERAKKVLEKYDVP 319
Query: 378 LTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPD 437
+ +G+FT + + + +++ +L FL GP + PK P E D
Sbjct: 320 YSVIGKFTDTGRVVLYYNGEKVADLPAKFLAEGPELDR-PYERPKWHLELELLPPLPEVD 378
Query: 438 LNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKK 497
L A++ V++ V SK I YDHEVQ TV++P +G DAAV++ +E + K
Sbjct: 379 LGDAIRKVLSSPNVASKRWIYEQYDHEVQIRTVVKPGEG-------DAAVLRLLE-DPPK 430
Query: 498 AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMW 557
+A++ NPR LDP AA EA RN VA+GA P A +D G P RP+ W
Sbjct: 431 GIAVATDSNPRYTFLDPLWGAADVFLEAYRNVVASGARP--LAAVDQVDAGSPERPDRFW 488
Query: 558 ALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVP 617
+ M P + GK SF NE GK+ I P+++I+ +G V ++
Sbjct: 489 FFVRMIDGLAWVEREVDVPIVGGKVSFYNED-DVTGKQ--IKPTVMITMIGKVENVYNAK 545
Query: 618 GSDFKKEGSAIYLVGKPQFSFGGSVFA-ELFGIPSGESAAVPPFKKEAAELYKKLHSNIM 676
+ +EG + LVG+ GGS F + + G+ PP + + E ++ I+
Sbjct: 546 RAR-AEEGDLLVLVGETFPELGGSEFLWSVHKLVRGK----PPVPRPSTE--ARVAERIL 598
Query: 677 KGLVLS----CHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLL 732
K + +S HD+S GGLAAA+ E+ G GA L+ D +LF E+ L
Sbjct: 599 KAIKVSGVTGVHDVSVGGLAAAVAELA-KGFGATLELDKVKGPWKRPEEALFSESGARYL 657
Query: 733 VEIKEE 738
+ +K E
Sbjct: 658 LAVKPE 663
>gi|154685145|ref|YP_001420306.1| PurL [Bacillus amyloliquefaciens FZB42]
gi|154350996|gb|ABS73075.1| PurL [Bacillus amyloliquefaciens FZB42]
Length = 742
Score = 300 bits (769), Expect = 2e-79, Method: Composition-based stats.
Identities = 218/650 (33%), Positives = 325/650 (50%), Gaps = 47/650 (7%)
Query: 101 VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAV 160
VL + AGI++ + V FK E+HNHPSAIEP+ GA TGVGG+IRDV + ARP AV
Sbjct: 74 VLQGPGEGAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIAV 133
Query: 161 TDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNP 220
+ L FG +P K + V+ G+ YGN +GIPTV G V + +Y NP
Sbjct: 134 LNSLRFGELTSP---------RVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDASYEGNP 184
Query: 221 LVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ K G+ ++ +G KTGRDG+ GATF+S M S+ + S+
Sbjct: 185 LVNAMCVGLIDHKDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEMSDSS-EEKRSA 243
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPV 336
VQ+G+P ++K + E ++ I D GA G +S+ EMAS G +++L IP
Sbjct: 244 VQVGDPFMEKLLLEACLEVIQCDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQ 303
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ G+ +E+ LSE+QERM++ + + + + + D D+E ++G T D +LR+R
Sbjct: 304 RETGMTAYEMMLSESQERMLLVIERGREQEIVDIFDKYDLEAVSVGHVTDDKMLRLRHNG 363
Query: 397 KEIINLSCGFLHSGPPQRKLKAAPPKDGKPF--IKYPEYKEPDLNAALKAVINHHAVNSK 454
+ + L L P +A P + F + P + D L A++ + SK
Sbjct: 364 EVVCELPVDALAEEAPVYHKPSAEPAYYREFQETEAPAPEVKDATETLFALLQQPTIASK 423
Query: 455 EDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDP 514
E + YD+ V+ TV+ P DA V++ T KKA+A++ N R LDP
Sbjct: 424 EWVYDQYDYMVRTNTVVAP--------GSDAGVLRIRGT--KKALAMTTDCNARYLYLDP 473
Query: 515 YAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFK 574
A+ EA RN V +GA+P A+ DN G+P +PE W + + A V
Sbjct: 474 EEGGKIAVAEAARNIVCSGAEP--LAVTDNLNFGNPEKPEIFWQIEKAADGISEACNVLS 531
Query: 575 TPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKP 634
TP I G S NE S G +I P+ +I +G++ D + FK+ G +Y++G+
Sbjct: 532 TPVIGGNVSLYNE---SNG--TAIYPTPVIGMVGLIEDTAHITTQHFKQAGDLVYVIGET 586
Query: 635 QFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL--YKKLHSNIMKGLVLSCHDLSEGGLA 692
+ F GS EL + G P EL K L I KG V S HD+SEGGL
Sbjct: 587 KPEFAGS---ELQKMTEGRIYGKAPQIDLDIELSRQKALLDAIKKGFVQSAHDVSEGGLG 643
Query: 693 AALYE--MCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENR 740
A+ E M +GA + + + A LF E+ +V +K+E++
Sbjct: 644 VAIAESVMTTENLGANVTVE-------GEAALLFSESQSRFVVSVKKEHQ 686
>gi|21226962|ref|NP_632884.1| Phosphoribosylformylglycinamidine synthase [Methanosarcina mazei
Go1]
gi|20905275|gb|AAM30556.1| Phosphoribosylformylglycinamidine synthase [Methanosarcina mazei
Go1]
Length = 664
Score = 300 bits (768), Expect = 3e-79, Method: Composition-based stats.
Identities = 211/619 (34%), Positives = 310/619 (50%), Gaps = 47/619 (7%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
D+A II+F++ Y ++ E+HNHPS ++P+ GA TGVGG++RD++ + ARP A+ D L F
Sbjct: 7 DDAAIIKFEDGYVLAIGMESHNHPSYVDPYNGAATGVGGIVRDIISMGARPIALMDPLYF 66
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G DTP + +I+G+ YGN +G+P VNG + Y+ NPLV
Sbjct: 67 GPLDTPKNLF---------LFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPLVNVVA 117
Query: 227 AGIAPRGKHRTKPS--AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K T S AG+ +I G TG+DGL GA+F+S + S SVQ+G+P
Sbjct: 118 VGLCKEEKVMTSRSQKAGNKLILAGSSTGKDGLGGASFASRDLSESAEAEDRPSVQVGDP 177
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLA 342
+K V E+ ++A D+G + D GA G A E+A+ LG + +P + +
Sbjct: 178 YTEKLVMEMTLEAIDKGYIKSCKDLGAAGLGGASSELAAKGGLGAYIIADAVPQREPEMN 237
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
+E+ L+E+QERMV V + ++A+ L D+ +G T V F + + ++
Sbjct: 238 AYEILLAESQERMVFEVAPEDVDAVLALVQKYDLNGAVIGHLTEKPNYTVEFRGEIVADI 297
Query: 403 SCGFLHSGPPQRKLKAAPP---KDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVR 459
GFL G P + + P ++GK PE E DL AA V++ H + SKE I R
Sbjct: 298 PIGFLTGGAPTCEKPSEAPIHREEGKK----PETPE-DLKAAFMKVLSSHNIASKEWIYR 352
Query: 460 LYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAA 519
YDHEVQ TV++P +D+ V++ + KK +A+S PR LLDPY
Sbjct: 353 QYDHEVQLRTVVKP--------GEDSGVLRITD---KKGIALSCGCQPRATLLDPYTGGR 401
Query: 520 SAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFIS 579
+AI E N GA E AI++ G+P PET W + A P +
Sbjct: 402 TAIIENAMNLAVKGA--EGLAIVNCLNFGNPENPETYWQFKNAVLGLGDAARELSIPVVG 459
Query: 580 GKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFG 639
G S NE S+ R +IPP+ I +G V +P F K G +I LVG+ G
Sbjct: 460 GNVSLYNE---SDEFRTAIPPTPSIGMIGKVDLETPLPSGFFAKTGDSIILVGETVPEMG 516
Query: 640 GSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC 699
GS + G +G + VP K A E+ K + + G + S HD+S GG+ A L MC
Sbjct: 517 GSEYYSCMG--AGNAGKVPEVPKNAPEIIKAVIEAVKSGKLNSAHDISLGGIGAGLARMC 574
Query: 700 --------LSGIGAELKED 710
+S I +KED
Sbjct: 575 KNMGGKVDVSEIAGGMKED 593
>gi|15828188|ref|NP_302451.1| phosphoribosylformylglycinamidine synthase subunit II
[Mycobacterium leprae TN]
gi|14916654|sp|Q50023|PURL_MYCLE Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|699222|gb|AAA62986.1| purL [Mycobacterium leprae]
gi|2076635|emb|CAB08431.1| PurL [Mycobacterium leprae]
gi|13093742|emb|CAC31166.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium
leprae]
Length = 754
Score = 300 bits (768), Expect = 3e-79, Method: Composition-based stats.
Identities = 233/756 (30%), Positives = 354/756 (46%), Gaps = 83/756 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E + +RE +RP TD E + WSEHC +K+ K + G + TEE +
Sbjct: 27 EYQRVREILG--RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTTEEMRTG----- 78
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 79 --------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAA 118
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D L +R++ GV+ G+ YGN
Sbjct: 119 TGVGGIVRDIMAMGARPVAVMDQLRFGAAD---------ALDTRRVLDGVVRGIGGYGNS 169
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + Y NPLV C G+ + H S AG+ II G TG DG+
Sbjct: 170 LGLPNIGGETVFDSCYDGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGACTGLDGIG 229
Query: 259 GAT-FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSA 317
G + +S DA SVQ+G+P ++K + E ++ GL I D G G S A
Sbjct: 230 GVSVLASDTFDAEGARKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCA 289
Query: 318 VGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND 375
E+ASA +G + L +P + + + P E++ SE+QERM V + ++A +C +
Sbjct: 290 TSELASAGDVGMAIQLDTVPRRAKDMTPAEVFCSESQERMCAVVAPENVDAFLAVCRKWE 349
Query: 376 VELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAPPK------DGKPFI 428
V T +G T LR+ + + ++++ + H GP ++ + P D +
Sbjct: 350 VLATVIGEVTDGDRLRITWHGETVVDVPPRTVAHEGPVYQRPVSRPESQEALNADSSKGL 409
Query: 429 KYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI 488
P + +L A L A++ + S+ I YD V+G TVL + DA V+
Sbjct: 410 PRPVSGD-ELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADAGVL 460
Query: 489 KPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLG 548
+ E+ G + +A+S + R LDPYA A A+ EA RN GA P A+ + G
Sbjct: 461 RIDESTG-RGIALSTDASGRYTRLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCLNFG 517
Query: 549 DPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMG 608
P P MW + R + K P G SF N+ + V+I P+ ++ +G
Sbjct: 518 SPEDPGVMWQFAQAVRGLADGCAALKIPVTGGNVSFYNQTGA-----VAILPTPVVGVLG 572
Query: 609 IVPDIGRVPGSDFKKE-GSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE- 666
++ ++ R + E G + L+G F GSV+A++ +G +PP A E
Sbjct: 573 VLDNVARRIHTSLGTEPGEILMLLGDTYDEFDGSVWAQVM---AGHLGGLPPMVDLAREK 629
Query: 667 -LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL---SGIGAELKEDFHTRLGASKIAS 722
L + L S LV + HDLSEGGLA A+ E L +G L ED A
Sbjct: 630 LLAEVLSSASRDELVSAAHDLSEGGLAQAIVESALAGETGCRIALPED------ADPFVM 683
Query: 723 LFGETTGCLLVEIKEENRSAFEK--EMEGASIYEIG 756
LF E+ G +LV + S F E G IG
Sbjct: 684 LFSESAGRVLVAVPRPEESRFRSMCEARGLPAMRIG 719
>gi|68229525|ref|ZP_00568719.1| Phosphoribosylformylglycinamidine synthase II [Frankia sp. EAN1pec]
gi|68202896|gb|EAN17074.1| Phosphoribosylformylglycinamidine synthase II [Frankia sp. EAN1pec]
Length = 769
Score = 300 bits (767), Expect = 4e-79, Method: Composition-based stats.
Identities = 235/739 (31%), Positives = 349/739 (47%), Gaps = 90/739 (12%)
Query: 31 TEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIK 90
T R TDAE + WSEHC +K+ K + Q + P
Sbjct: 45 TLGRVPTDAELAMYSVMWSEHCSYKSSKVHL---------RQFRDTP------------- 82
Query: 91 KATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDV 150
ATD + L +NAG+++ E V+FK E+HNHPS +EP+ GA TGVGG++RD+
Sbjct: 83 -ATDRL-----LVGMGENAGVVDVGEGLAVTFKVESHNHPSFVEPYQGAATGVGGIVRDI 136
Query: 151 MGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGV 210
+ + ARP + D L FG D P R++ GV+ G+ YGN +G+PT+ G V
Sbjct: 137 LTMGARPIGILDPLRFGAADAP---------DTARVLPGVVAGIGGYGNCLGLPTIGGEV 187
Query: 211 HYHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGAT-FSSMVM 267
+ Y NPLV C G+ P G+ +T + G+ ++ LG KTGRDG+ G + +S
Sbjct: 188 VFDPVYGGNPLVNALCVGVMPVGRVQTSAATGVGNAVVLLGAKTGRDGIGGVSVLASATF 247
Query: 268 DASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--- 324
D G SVQ+G+P +K + E ++ D+GL + I D G G + A+ E +A
Sbjct: 248 DEGGGPARRPSVQVGDPFTEKILIECCLELFDRGLVTGIQDLGGAGLTCALTETTAAGIA 307
Query: 325 ----LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTN 380
G +VDL +P++ +A E+ SE+QERM+ V D L + L + V TN
Sbjct: 308 TGQPGGMEVDLDLVPLREASMAAHEVLASESQERMLAIVTPDALPEVLALAERWGVIATN 367
Query: 381 LGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPP-----KDGKPFIKYPEY 433
+G T L VR+ + ++++ G L P +R L+ D ++ P
Sbjct: 368 IGTVTDSGRLVVRWHGEVVVDVPPGSLADDGPVYERPLRRPADLDLLRADAPSALERPRT 427
Query: 434 KEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMET 493
+ L A L +I + S+ + YD VQ TVL P+DA V++ +
Sbjct: 428 GDA-LRATLLRMIASPNLCSRAWVTEQYDRYVQANTVLAQ--------PEDAGVLR-LSA 477
Query: 494 EGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRP 553
G +A++ N R LDP+A A A+ EA RN AAGA+P A+ + G P P
Sbjct: 478 SG-LGIALATDGNGRYARLDPFAGAQLALAEACRNVTAAGAEP--IAVTNCLNFGSPEDP 534
Query: 554 ETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDI 613
E MW + + P G SF N+ S+ I P+ ++ +G+ D+
Sbjct: 535 EVMWQFAQACAGLADACRRLGLPVTGGNVSFYNQTGSA-----PIHPTPVVGVLGLFDDV 589
Query: 614 GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYK-KLH 672
R F EG A+ L+G + FGGS +A G PP A +L + KL
Sbjct: 590 TRRTPIGFTDEGDALLLLGDTRDEFGGSEWA---WATHGHLGGTPP----AVDLEREKLL 642
Query: 673 SNIM-----KGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGE 726
I+ +GL+ + HDLSEGGLA AL E CL G GA ++ GA LF E
Sbjct: 643 GEILVGGSREGLLTAAHDLSEGGLAQALVESCLRGGHGARIE----LPAGADAFVELFSE 698
Query: 727 TTGCLLVEIKEENRSAFEK 745
+ G +V + + F +
Sbjct: 699 SAGRAVVAVPAAEQDRFAR 717
Score = 60.1 bits (144), Expect = 6e-07, Method: Composition-based stats.
Identities = 68/286 (23%), Positives = 120/286 (41%), Gaps = 27/286 (9%)
Query: 107 DNAGIIEFDEK-YEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
++AG++ ++ + + + ++PF GA + R+V A P AVT+ L
Sbjct: 468 EDAGVLRLSASGLGIALATDGNGRYARLDPFAGAQLALAEACRNVTAAGAEPIAVTNCLN 527
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPL---V 222
FG P+ P + G+ D ++G+P G V ++ S P+
Sbjct: 528 FGSPEDP---------EVMWQFAQACAGLADACRRLGLPVTGGNVSFYNQTGSAPIHPTP 578
Query: 223 YCGCAGIAPRGKHRTK---PSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
G G+ RT GD ++ LG RD G+ ++ A+ G + G+
Sbjct: 579 VVGVLGLFDDVTRRTPIGFTDEGDALLLLGDT--RDEFGGSEWAW----ATHGHLGGTPP 632
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQ 339
+ + +K + E+L+ +GL +A D GG + A+ E G A+I +
Sbjct: 633 AV-DLEREKLLGEILVGGSREGLLTAAHDLSEGGLAQALVESCLRGGHG---ARIELPAG 688
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFT 385
A EL+ SE+ R V+AVP + + +LC + +G T
Sbjct: 689 ADAFVELF-SESAGRAVVAVPAAEQDRFARLCADRGLPCRQIGVVT 733
>gi|29376329|ref|NP_815483.1| phosphoribosylformylglycinamidine synthase II [Enterococcus
faecalis V583]
gi|67460941|sp|Q833Y9|PURL_ENTFA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|29343792|gb|AAO81553.1| phosphoribosylformylglycinamidine synthase II [Enterococcus
faecalis V583]
Length = 739
Score = 300 bits (767), Expect = 4e-79, Method: Composition-based stats.
Identities = 237/721 (32%), Positives = 348/721 (48%), Gaps = 79/721 (10%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + K +P + P VL +
Sbjct: 49 WSEHCSYKNSKPVL------------KKFP------------------TEGPQVLQGPGE 78
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V FKAE+HNHPSA+EP+ GA TGVGG+IRD+ + ARP A+ D L FG
Sbjct: 79 GAGIVDIGDGLAVVFKAESHNHPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFG 138
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
T A + + V+ G+ YGN +GIPTV G + + Y NPLV C
Sbjct: 139 EL-TDART--------RYLFQEVVAGISGYGNCIGIPTVGGEIAFEPCYQGNPLVNAMCV 189
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG-SSVQIGE 283
G+ R K A G+ I+ +G KTGRDG+ GATF+S + S G+ S+VQ+G+
Sbjct: 190 GLI-RHDEIQKGQAKGVGNSILYVGAKTGRDGIHGATFAS--EEFSEGEEQQRSAVQVGD 246
Query: 284 PIIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMASALGCD--VDLAKIPVKYQ 339
P ++K + E +D Q + I D GA G S+ EMAS G ++L K+P +
Sbjct: 247 PFMEKLLLEACLDLIKNHQDILIGIQDMGAAGLVSSSAEMASKAGSGLILELDKVPQRET 306
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEI 399
++P+E+ LSE+QERM+I V + + +L D+E +G T D RV G K +
Sbjct: 307 QMSPYEMLLSESQERMLICVEKGAEQQVCELFQTYDLEAVAIGSVTDDGQYRVFHGGKIV 366
Query: 400 INLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAA--LKAVINHHAVNSKEDI 457
++ L P + P+ + F K + N+ LK ++ + SK+ +
Sbjct: 367 ADVPVDALAEEAPVYQKAYQEPERMRAFKKLAPFIPEITNSTELLKRLLQQPTIASKKSV 426
Query: 458 VRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAA 517
YD +VQ TV++P DAAV++ T KA+A++ N R L+P
Sbjct: 427 YETYDSQVQTNTVVQP--------GSDAAVLRVRGT--NKALAMTTDCNSRYLYLNPEIG 476
Query: 518 AASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPF 577
A+ EA RN VA+GA P AI D G P++PE+ W L A TP
Sbjct: 477 GQIAVAEAARNIVASGAQP--LAITDCLNYGSPDKPESFWELWTSADGIAAACRQLGTPV 534
Query: 578 ISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFS 637
ISG S NE ++G+ +I P+ +I +G++ D+ ++ FK+ IYL+G+
Sbjct: 535 ISGNVSLYNE---TDGQ--AIYPTPMIGMVGVIEDVSQITTQAFKQVDDLIYLIGETHAD 589
Query: 638 FGGSVFAEL-FGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALY 696
F GS ++ G G+ + K+E A L + I GLV S HD +EGG+A AL
Sbjct: 590 FNGSEIQKIQLGRIEGQLRSF-DLKEEKANQELVLKA-IQVGLVASAHDCAEGGVAVALA 647
Query: 697 EMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIG 756
E S EL L K LF ET ++ + +++ AFE + G IG
Sbjct: 648 E---SAFANELGLQVTLPL---KKEYLFAETQSRFILSVSPQHQEAFET-LIGRKAQHIG 700
Query: 757 K 757
K
Sbjct: 701 K 701
>gi|1144520|gb|AAB41455.1| phosphoribosylformylglycinamidine synthase
Length = 754
Score = 299 bits (765), Expect = 5e-79, Method: Composition-based stats.
Identities = 228/741 (30%), Positives = 352/741 (47%), Gaps = 81/741 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R IR+ ++RP TD E + WSEHC +K+ + G + ++E +
Sbjct: 27 EYRRIRQIL--DRRP-TDTELAMYSVMWSEHCSYKSSAVHLRYFGETTSDEMRAV----- 78
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 79 --------------------MLVGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAP 118
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P +R++ GV+ G+ YGN
Sbjct: 119 TGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVRGIGGYGNS 169
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLR 258
+G+P + G + YA NPLV C G+ + H S AG+ II G +TG DG+
Sbjct: 170 LGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIG 229
Query: 259 GATFSSMVMDASTGDVAGS-----SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGG 313
G + V+ + T D GS SVQ+G+P ++K + E ++ GL I D G G
Sbjct: 230 GVS----VLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAG 285
Query: 314 YSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLC 371
S A E+ASA G + L +P++ + + P E+ SE+QERM V ++A +C
Sbjct: 286 LSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVC 345
Query: 372 DANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAP-PKDGKPFIK 429
+V T +G T L++ + + ++++ + H GP ++ A P +D +
Sbjct: 346 RKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADR 405
Query: 430 YPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDA 485
+ P +L A L A++ + S+ I YD V+G TVL + D
Sbjct: 406 SAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ADG 457
Query: 486 AVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
+++ E+ G + +A+S + R LLDPYA A A+ EA RN GA P A+ +
Sbjct: 458 GMLRIDESTG-RGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATP--VAVTNCL 514
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P MW + R + P G SF N+ S+ +I P+ ++
Sbjct: 515 NFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSA-----AILPTPVVG 569
Query: 606 AMGIVPDI-GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA 664
+G++ D+ R+P + G + L+G + F GSV+A+ + + +PP A
Sbjct: 570 VLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQ---VTADHLGGLPPVVDLA 626
Query: 665 AE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIAS 722
E L L S GLV + HDLSEGGLA A+ E L+G E GA
Sbjct: 627 REKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAG---ETGCRIVLPEGADPFVL 683
Query: 723 LFGETTGCLLVEIKEENRSAF 743
LF E+ G +LV + S F
Sbjct: 684 LFSESAGRVLVAVPRTEESRF 704
Score = 73.2 bits (178), Expect = 6e-11, Method: Composition-based stats.
Identities = 80/320 (25%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ D G++ DE ++ +
Sbjct: 429 PHLCSRAFITEQYDRYVRGNT-------VLAEHAD-GGMLRIDESTGRGIAVSTDASGRY 480
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+ ++P+ GA + R+V A P AVT+ L FG P+ P + + G+
Sbjct: 481 TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGV-----MWQFTQAVRGL 535
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSAG---DH 244
+G D +GIP G V ++ S P G G+ + R G
Sbjct: 536 ADGCAD----LGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGE 591
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
+ L G T RD G+ ++ + T D G + + +K +A VL A GL S
Sbjct: 592 TLMLLGDT-RDEFDGSVWAQV-----TADHLGGLPPVVDLAREKLLAAVLSSASRDGLVS 645
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG + A+ E +A GC + L +G P+ L SE+ R+++AVP
Sbjct: 646 AAHDLSEGGLAQAIVESALAGETGCRIVLP------EGADPFVLLFSESAGRVLVAVPRT 699
Query: 363 KLEALQKLCDANDVELTNLG 382
+ + +C+A + +G
Sbjct: 700 EESRFRGMCEARGLPAVRIG 719
>gi|15669450|ref|NP_248260.1| phosphoribosylformylglycinamidine synthase II (purL)
[Methanocaldococcus jannaschii DSM 2661]
gi|6685822|sp|Q58660|PURL_METJA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|1591899|gb|AAB99270.1| phosphoribosylformylglycinamidine synthase II (purL)
[Methanocaldococcus jannaschii DSM 2661]
Length = 733
Score = 299 bits (765), Expect = 5e-79, Method: Composition-based stats.
Identities = 223/731 (30%), Positives = 365/731 (49%), Gaps = 63/731 (8%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E WSEHC ++T K + + ++ E+ K
Sbjct: 21 ELAMFENLWSEHCAYRTSKKLLRMFAKTVNEKTSKN------------------------ 56
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
++ D+A +I ++ E+HNHPS I+P+ GA TGVGG++RDV+ + A+P A
Sbjct: 57 -IVVGIGDDAAVIRLKNDICLAIAMESHNHPSYIDPYNGAATGVGGIVRDVLSMGAKPIA 115
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ D L FG + K + +I GV++G+ DYGN++G+PTV G + ++ N
Sbjct: 116 LLDPLRFG------DIFGKEGDKVRWLIEGVVKGIGDYGNRIGVPTVGGECEFDSSFDYN 169
Query: 220 PLVYCGCAGIAPRGKHRT-KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
LV C G+ + T K + L G TGRDG+ GA+F+S + + + S
Sbjct: 170 NLVNVVCVGLVKENEIITGKAKEPGLSLILIGSTGRDGIGGASFASKDLTEESEE-ERPS 228
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEM--ASALGCDVDLAKIPV 336
VQ+G+ +K + + +++A G A+ D GA G S A EM +GC++ L + +
Sbjct: 229 VQVGDAFSEKCLIDAVLEAVKTGKVKAMKDLGAAGLSGASSEMCYGGGVGCELYLENVVL 288
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGE 396
+ + L P+E+ +SE+QERM++AV E + ++ ++ + +G+ + + ++
Sbjct: 289 R-EPLTPYEIMVSESQERMLLAVEPGSEEEIIEIFKKYELPASVIGKTIPEKRIIAKYKG 347
Query: 397 KEIINLSCGFLHSGP---PQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNS 453
+ +++L L P + K +D K IK PE DLNA L ++ + S
Sbjct: 348 EVVVDLPLDLLCEAPLYDREGKEDLKEKEDDKEKIKMPE----DLNAVLLKLLESPNICS 403
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
KE I + YDHEVQ TV++P +DAAV++ E +A++ N R L+
Sbjct: 404 KEWIYQQYDHEVQIRTVVKP--------GKDAAVLRINEVY-PMGIALTTDCNSRYCKLN 454
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVF 573
PY A +A+ EAVRN GA+P A+LDN G+P RPE W L E + + A F
Sbjct: 455 PYVGAVNAVAEAVRNLATVGAEP--IAMLDNLNFGNPERPERFWQLAECIKGLADAAEFF 512
Query: 574 KTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPG--SDFKKEGSAIYLV 631
+ P + G S NE + EGK I P+ I +G V D+ +VPG + KEG + +
Sbjct: 513 EIPVVGGNVSLYNETV-IEGKEHPINPTPAIFVLGKVEDVEKVPGVLDNKIKEGDILIIT 571
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA-AELYKKLHSNIMKGLVLSCHDLSEGG 690
+ + GGS + ++ I + E VP E ++Y+++ + +GLV D S GG
Sbjct: 572 NETKDEMGGSEYYKV--IHNTEEGRVPRVDLEKEKKIYEEVREVVKEGLVSEAVDCSRGG 629
Query: 691 LAAALYEMC-LSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
LA AL +M L+ IG E+ + + LF ET+G +++ +++EN+ ++
Sbjct: 630 LAVALAKMAVLNNIGLEVDLTEYNKNNLRDDILLFSETSGRIILAVRDENKDKVLSKL-- 687
Query: 750 ASIYEIGKTCG 760
+S Y IGK G
Sbjct: 688 SSAYIIGKVGG 698
Score = 63.9 bits (154), Expect = 4e-08, Method: Composition-based stats.
Identities = 78/314 (24%), Positives = 141/314 (44%), Gaps = 45/314 (14%)
Query: 108 NAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
+A ++ +E Y ++ + ++ + P+ GA V +R++ V A P A+ D L
Sbjct: 426 DAAVLRINEVYPMGIALTTDCNSRYCKLNPYVGAVNAVAEAVRNLATVGAEPIAMLDNLN 485
Query: 166 FGHPDTPAENVPKGTLHPKRI--ISGVIEGVKDYGNKMGIPTVNGGVH-YHEA------Y 216
FG+P+ P+R ++ I+G+ D IP V G V Y+E +
Sbjct: 486 FGNPE-----------RPERFWQLAECIKGLADAAEFFEIPVVGGNVSLYNETVIEGKEH 534
Query: 217 ASNPLVYCGCAGIAPR-----GKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
NP G G K GD I+ + +T +D + G+ + ++ +
Sbjct: 535 PINPTPAIFVLGKVEDVEKVPGVLDNKIKEGD-ILIITNET-KDEMGGSEYYKVIHNTEE 592
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDV 329
G V ++ +KK+ E + + +GL S DC GG + A+ +MA + +G +V
Sbjct: 593 GRVPRVDLEK-----EKKIYEEVREVVKEGLVSEAVDCSRGGLAVALAKMAVLNNIGLEV 647
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPND-KLEALQKLCDANDVELTNLGRFTGDA 388
DL + L L SE R+++AV ++ K + L KL A + G+ G +
Sbjct: 648 DLTE--YNKNNLRDDILLFSETSGRIILAVRDENKDKVLSKLSSAYII-----GK-VGGS 699
Query: 389 VLRVRFGEKEIINL 402
L+++ EK+++NL
Sbjct: 700 RLKIKINEKDVVNL 713
>gi|58337819|ref|YP_194404.1| phosphoribosylformylglycinamidine synthase [Lactobacillus
acidophilus NCFM]
gi|67460736|sp|Q5FIV1|PURL_LACAC Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|58255136|gb|AAV43373.1| phosphoribosylformylglycinamidine synthase [Lactobacillus
acidophilus NCFM]
Length = 742
Score = 299 bits (765), Expect = 6e-79, Method: Composition-based stats.
Identities = 227/737 (30%), Positives = 356/737 (48%), Gaps = 94/737 (12%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K K+ P ++K + K + P
Sbjct: 42 EIGLFSAMWSEHCSYK------------------KSKP------VLKLFPTKGKRVVQGP 77
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
+ AG+++ D+ V FKAE+HNHP+ +EP+ GA TGVGG++RDV + ARP A
Sbjct: 78 G------EGAGVVDIDDGQAVVFKAESHNHPTTVEPYQGAATGVGGILRDVFSMGARPVA 131
Query: 160 VTDVLCFGH-PDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
+ D L FG D P T+ K + I+GV DYGN MGIP + G + Y
Sbjct: 132 ILDSLHFGELKDNP-------TMRYK--MEETIKGVGDYGNCMGIPNLGGETTFDPCYNG 182
Query: 219 NPLVYCGCAGIA--PRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
N L+ GI +H G+ ++ +G KTGRDG+ GATF+S
Sbjct: 183 NILLNAMNVGIMDIKDMEHGDATGVGNAVMYVGAKTGRDGIHGATFASADFSEEHA-TQR 241
Query: 277 SSVQIGEPIIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLA 332
S+VQ+G+P ++K + E ++ + I D GA G S+ EMA+ G D++L
Sbjct: 242 SAVQVGDPFMEKLLMEACLELILHHREWLVGIQDMGAAGIVSSSAEMATEGKSGMDLNLN 301
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
+P + ++ +E+ LSE+QERM++ V E ++K+ D +++ +GR T D +
Sbjct: 302 LVPQREPNMSAYEIMLSESQERMLLCVKKGHEEDVKKIFDEYNLDAVTIGRITDDGRYVL 361
Query: 393 RFGEKEIINLSCGFL---------HSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALK 443
++ + ++ L PQR + ++ +P I+ D L+
Sbjct: 362 HHDDQVVCDIPVVTLTEKVLEEKSEEKKPQRIIDVEQSENWQPEIE-------DAGQTLR 414
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN 503
A++N + + + + + YD +V+ T++ P D+ +++ T KKA+A++
Sbjct: 415 ALLNQPTIANDQFVTQQYDSQVRTDTIVGP--------GSDSGILRVRHT--KKAIAMTT 464
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
N R LDP + E+ N VA+GA P AI D GDPN PE W L +
Sbjct: 465 DTNGRFVYLDPKVGGQRTVLESATNIVASGALP--LAITDCLNYGDPNDPEIFWELHQSC 522
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
+ + + +TP +SG S NE + GK +I PS +I +G++ + V +
Sbjct: 523 QGIADACEILETPVVSGNVSLYNE---NNGK--AIYPSPMIGMVGLIKNYDHVIPMHMQT 577
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVP--PFKKEAAELYKKLHSNIMKGLVL 681
G IYLVGK F GS EL + +G+ + +P P + KL + +GLV
Sbjct: 578 AGDKIYLVGKTDDDFAGS---ELQKMMTGKISGLPHAPNLPGIKDYLYKLQKLMAEGLVQ 634
Query: 682 SCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENR 740
S HDLSEGGL +L E + +G +K DF+ L LF ET G L+V + EN
Sbjct: 635 SAHDLSEGGLGVSLAESVFDTDLGVNVKLDFNKNL-------LFSETPGRLIVSVAPENA 687
Query: 741 SAFEKEMEGASIYEIGK 757
+ FE+EM G ++ EIG+
Sbjct: 688 AKFEQEM-GDAVSEIGQ 703
>gi|23125357|ref|ZP_00107294.1| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain [Nostoc punctiforme PCC 73102]
Length = 788
Score = 298 bits (764), Expect = 7e-79, Method: Composition-based stats.
Identities = 224/749 (29%), Positives = 345/749 (46%), Gaps = 94/749 (12%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P +
Sbjct: 38 AELGMFGVMWSEHCCYKNSRPLL------------KQFP------------------TEG 67
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
P +L +NAG+++ + +++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 68 PRILVGPGENAGVVDLGDGLQLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 127
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
A+ + L FG + +R+ GV+ G+ YGN +G+PTV G V++ AY+
Sbjct: 128 ALLNSLRFGSLEDAKT---------QRLFQGVVAGISHYGNCVGVPTVGGEVYFDPAYSG 178
Query: 219 NPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVM-DASTGDV 274
NPLV G+ + K A G+ ++ +G TGRDG+ GA+F+S + D S D
Sbjct: 179 NPLVNVMALGLM-ETQEIVKSGASGLGNPVLYVGSTTGRDGMGGASFASAELSDQSIDD- 236
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLA 332
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL
Sbjct: 237 -RPAVQVGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAAKGGVGIELDLD 295
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
KIP + G+ P+E LSE+QERM+ + + L + ++ G + ++R+
Sbjct: 296 KIPARETGMVPYEYLLSESQERMLFVAHKGREQELIDIFHRWGLQAVVAGTVIAEPIVRI 355
Query: 393 RFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAA--------- 441
F + L P R+L A PP+ + ++ P A
Sbjct: 356 LFQGGVAAEIPAEALAENTPLYNRELLAEPPEYARQAWEWTPDSLPACTTAGIEIQGGQQ 415
Query: 442 -----LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPMET- 493
L +++ + SK + R YDH+VQ TV+ P DAAVI +P+E
Sbjct: 416 SWNDILLTLLDTPTIASKNWVYRQYDHQVQNNTVILPGGA-------DAAVIRLRPLEEI 468
Query: 494 --------EGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
K VA + NPR L PY A + + EA RN GA+P A+ DN
Sbjct: 469 PNLKSKIPNLKLGVAATVDCNPRYVYLHPYEGAKAVVAEAARNLSCVGAEP--LAVTDNL 526
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P +P W L E R TP G S NE L S+G I P+ ++
Sbjct: 527 NFGSPEKPIGYWQLAEACRGLAEGCRELATPVTGGNVSLYNETLDSQGIPQPIYPTPVVG 586
Query: 606 AMGIVPDIGRVPGSDFKKEGSAIYLVGKP---QFSFGGSVFAELFGIPSGESAAVPPFKK 662
+G++PDI ++ G ++ G IYL+G P + S G S E A PP
Sbjct: 587 MVGLIPDITKICGQGWQASGDVIYLLGLPLASKISLGAS---EYLATIHNTVAGKPPLVD 643
Query: 663 EAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASK 719
E + K I G + S HD +EGG+A AL E C++G +GAE+ + +
Sbjct: 644 FDLERRVQKVCREGIRNGWIRSAHDSAEGGVAIALAECCIAGNLGAEINLEI-APMQNRV 702
Query: 720 IASLFGETTGCLLVEIKEENRSAFEKEME 748
LF E +LV + ++ +E ++
Sbjct: 703 DEMLFAEGGARILVSVTSAQQAIWESYLQ 731
>gi|50843424|ref|YP_056651.1| phosphoribosylformylglycinamidine synthase subunit II
[Propionibacterium acnes KPA171202]
gi|67460805|sp|Q6A6C0|PURL_PROAC Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|50841026|gb|AAT83693.1| phosphoribosylformylglycinamidine synthase II [Propionibacterium
acnes KPA171202]
Length = 750
Score = 298 bits (764), Expect = 8e-79, Method: Composition-based stats.
Identities = 223/700 (31%), Positives = 328/700 (46%), Gaps = 81/700 (11%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E + IRE +RP T E + WSEHC +K+ K + G +Q P
Sbjct: 27 EYQRIREILG--RRP-TGGELAMYSVMWSEHCSYKSSKKYLRRFGD--LPQQTPLGP--- 78
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ DNAG+++ V+FKAE+HNHPS +EP GA
Sbjct: 79 --------------------LLAGIGDNAGVVDIGNGLAVTFKAESHNHPSYVEPHQGAA 118
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP V + L FG D P R++ GV+ G+ DYGN
Sbjct: 119 TGVGGIVRDIMAMGARPVGVMNALAFGPLDAP---------DTARVLPGVVSGIADYGNC 169
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLR 258
+G+PT+ G + Y NPLV C G+ + G+ ++ G TG DG+
Sbjct: 170 LGLPTIGGQTLFDPTYYGNPLVNALCVGVLRHEDLQFAKASGVGNLVVLFGAATGGDGIG 229
Query: 259 GATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAV 318
GA+ + A+ G+ SVQ+G+P ++K + E +D + G+ A+ D GA G S A
Sbjct: 230 GASILASESFAAEGESKRPSVQVGDPFMEKLLIECTLDLFNAGVVEALQDFGAAGISCAT 289
Query: 319 GEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDV 376
E+ASA G V+L ++P++ LAP E+ +SE+QERM V D+L+ ++C V
Sbjct: 290 SELASAGDGGMHVELDRVPLRDPNLAPEEILMSESQERMAAVVRPDQLDRFMEICAHWGV 349
Query: 377 ELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP 436
T +G T L + + + I+++ + P + AA P E E
Sbjct: 350 AATVIGEVTDTGRLHIDWQGERIVDVDPRTVAHDGPVLDMPAARP------WWIDELNED 403
Query: 437 DLNA------------ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQD 484
D NA AL A++ + + I YD V+G TVL P D
Sbjct: 404 DANALPRDNSGEGLAGALLALVGSAQLCDRSWITDQYDRFVRGNTVLAQ--------PND 455
Query: 485 AAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDN 544
A +I+ + G +A+S N RQ L+PY A A+ EA RN +GA P A+ D
Sbjct: 456 AGMIRIDDNLG---IALSLDANGRQTTLNPYLGAQLALCEAYRNVAVSGATP--VAVTDC 510
Query: 545 FCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLI 604
G P P+ MW E + P G S +N SI P+ L+
Sbjct: 511 LNYGSPYDPDVMWQFDETILGLVDGCRELGVPVTGGNVSLHNRTGDE-----SIRPTPLV 565
Query: 605 SAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA 664
+G++ D+ R S F +G A+ L+G + FGGSV+ ++ I +G +PP
Sbjct: 566 GVLGVIDDVHRRIPSAFAHDGDAVLLLGTTKCEFGGSVYEDV--IHAGHLGGMPPMPDLN 623
Query: 665 AE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG 702
AE L + +GL+ S HDLS+GGLA AL E CL G
Sbjct: 624 AEKALAAVMVEASKRGLLSSAHDLSDGGLAQALVESCLQG 663
Score = 67.8 bits (164), Expect = 3e-09, Method: Composition-based stats.
Identities = 69/287 (24%), Positives = 123/287 (42%), Gaps = 36/287 (12%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
++AG+I D+ ++ + + + + P+ GA + R+V A P AVTD L +
Sbjct: 454 NDAGMIRIDDNLGIALSLDANGRQTTLNPYLGAQLALCEAYRNVAVSGATPVAVTDCLNY 513
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH-----EAYASNPL 221
G P P I G+++G ++ +G+P G V H E+ PL
Sbjct: 514 GSPYDP-----DVMWQFDETILGLVDGCRE----LGVPVTGGNVSLHNRTGDESIRPTPL 564
Query: 222 VYCGCAGIAPRGKHRTKPSA----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
V G G+ HR PSA GD ++ LG T + G+ + ++ G +
Sbjct: 565 V--GVLGVID-DVHRRIPSAFAHDGDAVLLLG--TTKCEFGGSVYEDVIHAGHLGGMP-- 617
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGE--MASALGCDVDLAKIP 335
+ + +K +A V+++A +GL S+ D GG + A+ E + LG V L +
Sbjct: 618 --PMPDLNAEKALAAVMVEASKRGLLSSAHDLSDGGLAQALVESCLQGGLGVSVSLPE-- 673
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
P + SE R ++++ + ++LC + V +G
Sbjct: 674 -----GEPSVMLFSETPARAIVSLCGNGYREFKELCQEHGVPTARIG 715
>gi|67921896|ref|ZP_00515412.1| Phosphoribosylformylglycinamidine synthase II [Crocosphaera
watsonii WH 8501]
gi|67856112|gb|EAM51355.1| Phosphoribosylformylglycinamidine synthase II [Crocosphaera
watsonii WH 8501]
Length = 768
Score = 298 bits (763), Expect = 1e-78, Method: Composition-based stats.
Identities = 230/743 (30%), Positives = 357/743 (48%), Gaps = 91/743 (12%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC +K + + K +P +
Sbjct: 34 AELGMFGVMWSEHCCYKNSRPLL------------KNFP------------------TEG 63
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
+L +NAG+++ + ++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 64 DRILVGPGENAGVVDLGKGLRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 123
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
A + L FG EN +RI SGV+EG+ YGN +G+PTV G ++++ AY
Sbjct: 124 ACLNSLRFGE----LENAKT-----RRIFSGVVEGISHYGNSVGVPTVGGEIYFNSAYNG 174
Query: 219 NPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSM-VMDASTGDV 274
NPLV G+ K K A G+ ++ +G TGRDG+ GA+F+S + D S D
Sbjct: 175 NPLVNAMALGLM-ETKDIVKSGASGIGNPVLYVGSTTGRDGMGGASFASAELTDQSMDD- 232
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLA 332
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL
Sbjct: 233 -RPAVQVGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAANGGVGIELDLD 291
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
KIPV+ G+ P+E LSE+QERM+ + + L + +++ G+ + ++R+
Sbjct: 292 KIPVRETGMVPYEYLLSESQERMLFVAQKGREQELIDIFQRWELQAVVAGKVIEEPIVRI 351
Query: 393 RFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAA--------- 441
F + + L P R+L PP+ + ++ E P A
Sbjct: 352 LFQGEIAAEIPANALADNTPIYHRELLENPPEYAQKAWQWTEDSLPSCTAEGIEIKGELK 411
Query: 442 -----LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPMETE 494
L +++ ++ SK+ + R YDH+VQ TV+ P DAAVI +P++ +
Sbjct: 412 TWNDILLTLLDTPSIASKKWVYRQYDHQVQNNTVIIPGGA-------DAAVIRVRPIDAK 464
Query: 495 G---KKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPN 551
K VA + N R LDP A +A+ EA RN GA P AI DN G P
Sbjct: 465 PDTCKIGVAATTDCNSRYVYLDPLEGAKAAVAEAARNLSCVGAKP--IAITDNLNFGSPE 522
Query: 552 RPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVP 611
W L + TP G S NE + S+G I P+ +I +G++
Sbjct: 523 NSIGYWQLALACQGISAGCQELNTPVTGGNVSLYNETVDSDGNPQPIYPTPVIGMVGLIE 582
Query: 612 DIGRVPGSDFKKEGSAIYLVG---KPQFSFGGSVF-AELFGIPSGESAAVPPFKKEAAEL 667
DI +V G ++ EG IYL+G KP S G S + A + I +G+ P E L
Sbjct: 583 DITKVCGQGWQNEGDIIYLLGVDNKP--SLGASEYLATIHDIVAGKP---PKVDFEQERL 637
Query: 668 YKKL-HSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFG 725
+K+ I + + S HD +EGGL AL E C+SG +GA+++ D+ + + LFG
Sbjct: 638 VQKICQEGISQSWIKSAHDCAEGGLMVALAECCISGNLGAKIQLDYQDKNRLDTV--LFG 695
Query: 726 ETTGCLLVEIKEENRSAFEKEME 748
E ++V + N+ +E ++
Sbjct: 696 EVCEQIIVSVSANNQQEWESYLQ 718
>gi|119718545|ref|YP_925510.1| phosphoribosylformylglycinamidine synthase II [Nocardioides sp.
JS614]
gi|119539206|gb|ABL83823.1| phosphoribosylformylglycinamidine synthase II [Nocardioides sp.
JS614]
Length = 751
Score = 298 bits (762), Expect = 1e-78, Method: Composition-based stats.
Identities = 236/761 (31%), Positives = 355/761 (46%), Gaps = 82/761 (10%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E IRE +RP T +E + WSEHC +K+ K + + L E + P
Sbjct: 27 EYARIREILG--RRP-TSSELAMYSVMWSEHCSYKSSKVHLK-QFSELAEVLAQRQP--- 79
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
DA +L+ +NAG+++ + Y V+FK E+HNHPS +EP+ GA
Sbjct: 80 ----------------DAGRLLAGIGENAGVVDIGQGYAVTFKVESHNHPSYVEPYQGAA 123
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD++ + ARP AV D L FG D + R++ G++ GV YGN
Sbjct: 124 TGVGGIVRDILAMGARPVAVMDPLRFGPLDADDTH---------RVLPGIVAGVGGYGNC 174
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPSA-GDHIISLGGKTGRDGLR 258
+G+P + G + Y NPLV C G+ H K S G+ +I G +TG DG+
Sbjct: 175 LGLPNIGGEAVFDATYLGNPLVNALCVGVLRHEDLHLAKASGVGNQVILYGARTGGDGIG 234
Query: 259 GAT-FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSA 317
G + +S DA G SVQ+G+P ++K + E ++ GL + I D G G S A
Sbjct: 235 GVSVLASETFDAD-GPAKRPSVQVGDPFMEKLLIECTLEIFAAGLVAGIQDLGGAGLSCA 293
Query: 318 VGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND 375
E+ASA G V+L ++P++ LAP E+ +SE+QERM+ V D + A +C D
Sbjct: 294 TSELASAGDGGMHVELDRVPLRDSTLAPEEILMSESQERMMAVVEPDDVAAFLAICAKWD 353
Query: 376 VELTNLGRFTGDAVLRVRFGEKEIINLSC-GFLHSGPPQRKLKAAPP------KDGKPFI 428
VE +G T L++ + + ++++ H GP + A P D +
Sbjct: 354 VEAVVVGEVTDTGRLQIDWHGERVVDVPPRSVAHDGPTYHRPFARPAWQDDLQADAAESL 413
Query: 429 KYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI 488
P + +L L ++ + K I YD V+G TVL P D+ ++
Sbjct: 414 PRPGSGD-ELRKTLLTLVASPNLCDKSWITDQYDRYVRGNTVLAQ--------PSDSGMV 464
Query: 489 KPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLG 548
+ ++ E VA++ N R LLDPYA A A+ EA RN GA P AI D G
Sbjct: 465 R-VDEETDLGVALATDCNGRFALLDPYAGAQLALAEAYRNVATGGATP--LAISDCLNFG 521
Query: 549 DPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMG 608
P P MW E R + L P G S N + +I P+ +++ +G
Sbjct: 522 SPEDPAVMWQFAEACRGLKDGCLELGIPVTGGNVSLYN-----QTGETAILPTPVVAVLG 576
Query: 609 IVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE-- 666
++ D+ R S + G ++L+G+ + GS +A + G +PP AE
Sbjct: 577 VIEDVTRRTPSAWSTGGERVFLLGETREELSGSEWAH---VVHGHLGGLPPQLDLEAERT 633
Query: 667 LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASL 723
L + LH + GLV S HDLS+GGLA AL E L G+ E+ +D L
Sbjct: 634 LAELLHDAV--GLVSSAHDLSDGGLAQALVEGALRHGVGVSVEVPDD--------AFVGL 683
Query: 724 FGETTGCLLVEIKE--ENRSAFEKEMEGASIYEIGKTCGKA 762
F E+ G ++V + + R E G + +G T G A
Sbjct: 684 FSESPGRVVVTVPDGAAERLVELAERHGVELTALGVTGGDA 724
Score = 74.7 bits (182), Expect = 2e-11, Method: Composition-based stats.
Identities = 81/291 (27%), Positives = 133/291 (45%), Gaps = 32/291 (10%)
Query: 108 NAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
++G++ DE+ + V+ + + + ++P+ GA + R+V A P A++D L
Sbjct: 460 DSGMVRVDEETDLGVALATDCNGRFALLDPYAGAQLALAEAYRNVATGGATPLAISDCLN 519
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLV 222
FG P+ PA + G+KD ++GIP G V + P
Sbjct: 520 FGSPEDPAVMWQ---------FAEACRGLKDGCLELGIPVTGGNVSLYNQTGETAILPTP 570
Query: 223 YCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
G+ RT PSA G + L G+T R+ L G+ ++ +V G + G
Sbjct: 571 VVAVLGVIEDVTRRT-PSAWSTGGERVFLLGET-REELSGSEWAHVVH----GHLGGLPP 624
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQ 339
Q+ + ++ +AE+L DA GL S+ D GG + A+ E A G V + +
Sbjct: 625 QL-DLEAERTLAELLHDA--VGLVSSAHDLSDGGLAQALVEGALRHGVGVSVEVPDDAFV 681
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVL 390
GL SE+ R+V+ VP+ E L +L + + VELT LG GDA++
Sbjct: 682 GL------FSESPGRVVVTVPDGAAERLVELAERHGVELTALGVTGGDALV 726
>gi|111610228|gb|ABH11607.1| phosphoribosylformylglycinamidine synthase [Lactobacillus
helveticus CNRZ32]
Length = 743
Score = 298 bits (762), Expect = 1e-78, Method: Composition-based stats.
Identities = 235/756 (31%), Positives = 375/756 (49%), Gaps = 93/756 (12%)
Query: 30 KTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYI 89
K KR E + WSEHC +K K+ P +++ +
Sbjct: 32 KLLKRLPNYTEIGLFSAMWSEHCSYK------------------KSKP------VLRLFP 67
Query: 90 KKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRD 149
K + P + AG+++ D+ V FKAE+HNHP+ +EP+ GA TGVGG++RD
Sbjct: 68 TKGKRVVQGPG------EGAGVVDIDDGQAVVFKAESHNHPTTVEPYQGAATGVGGILRD 121
Query: 150 VMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGG 209
V + ARP A+ D L FG +N P T+ K + I GV DYGN +GIP + G
Sbjct: 122 VFSMGARPVAILDSLHFGE----LKNNP--TMRYK--MEETIRGVGDYGNCIGIPNLGGE 173
Query: 210 VHYHEAYASNPLVYCGCAGIA--PRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVM 267
+ Y N L+ C G+ +H G+ I+ +G KTGRDG+ GATF+S
Sbjct: 174 TTFDSCYNGNILLNAMCVGLMNIKDMEHGKAVGLGNSIMYVGAKTGRDGIHGATFASADF 233
Query: 268 DASTGDVAGSSVQIGEPIIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMASA- 324
+ + S+VQ+G+P ++K + E ++ + + I D GA G S+ EMA+
Sbjct: 234 -SKEHETQRSAVQVGDPFMEKLLMEACLELILKHRDWLVGIQDMGAAGIVSSSAEMATEG 292
Query: 325 -LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGR 383
G +++L +P + ++ +E+ LSE+QERM++ V E ++K+ +++ +GR
Sbjct: 293 NAGMELNLDLVPQREPNMSAYEIMLSESQERMLLCVKKGHEEDVKKIFKDYNLDAVTIGR 352
Query: 384 -FTGDAVLRVRFGEK----EIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDL 438
G+ + GEK + +L+ L P +++K D + K P ++ P
Sbjct: 353 VIEGENYVLYHEGEKVCDIPVRSLTEDVLEE--PSKEIKPQYIIDAE---KMPAWR-PSF 406
Query: 439 NAA---LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEG 495
++ LK ++N + + + I + YD +V+ T+++P DA V++ T
Sbjct: 407 ESSGEILKRLLNQPTIANDQFITQQYDSQVRSNTIVKP--------GSDAGVLRIRHT-- 456
Query: 496 KKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPET 555
KKA+A+ N R L+P ++ E+V N VA+GA P AI D GDPN PE
Sbjct: 457 KKAIAMCTDTNGRFVYLNPKIGGQRSVIESVCNIVASGAKP--LAITDCLNYGDPNDPEI 514
Query: 556 MWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGR 615
W+L E + + +F+TP +SG S NE ++G+ +I PS +I +G++ +
Sbjct: 515 FWSLRESCQGIADACRIFETPVVSGNVSLYNE---NDGQ--AIYPSPMIGMVGLIKNTDY 569
Query: 616 VPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVP--PFKKEAAELYKKLHS 673
V ++ +YLVGK F GS E+ + G+ + +P P + + K LH
Sbjct: 570 VIPMHVQEADDIVYLVGKTTADFAGS---EVQKMLQGKISGLPEAPNLELIHDYLKNLHK 626
Query: 674 NIMKGLVLSCHDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETTGC 730
+ +GLV S HDLSEGGLA +L E G+ L E F L LF ET G
Sbjct: 627 AMTQGLVTSAHDLSEGGLAVSLAESVFDTEFGLNINLSE-FDKTL-------LFSETPGR 678
Query: 731 LLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
L+V +K EN+SAFE + G+++ EIG+ + L +
Sbjct: 679 LIVSVKPENKSAFE-SLLGSAVQEIGRVTDQRKLSI 713
>gi|37913021|gb|AAR05350.1| predicted phosphoribosylformylglycinamidine synthase II [uncultured
marine alpha proteobacterium HOT2C01]
Length = 732
Score = 297 bits (760), Expect = 2e-78, Method: Composition-based stats.
Identities = 223/717 (31%), Positives = 342/717 (47%), Gaps = 91/717 (12%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + W+EHC +K+ +K + T E+ PG
Sbjct: 40 ELGIFSAMWNEHCSYKS--SKFWLKKLPTTGERVVQGPG--------------------- 76
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
+NAG+I+ D+ FK E+HNHPS +EP+ GA TGVGG++RDV + ARP A
Sbjct: 77 -------ENAGVIDIDDGDVAVFKMESHNHPSFLEPYQGAATGVGGILRDVFTMGARPVA 129
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG P+ P K ++SGV+ G+ YGN +G+PTV G V++H +Y N
Sbjct: 130 NLNALRFGEPEHPKT---------KHLLSGVVSGIGGYGNCIGVPTVGGEVNFHPSYNGN 180
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV GIA + K + G+ ++ +G KTGRDG+ GAT +S D + D
Sbjct: 181 ILVNAMTVGIAKKDKIFYSAAAGVGNPVVYVGSKTGRDGIHGATMASAEFDEDSED-KKP 239
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIP 335
+VQ+G+P +K + E ++ + AI D GA G +S+ EMAS +G +++L+K+P
Sbjct: 240 TVQVGDPFTEKLLLEACLELMKEEAIIAIQDMGAAGLTSSSIEMASKGDVGLEINLSKVP 299
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
++ Q ++ +EL LSE+QERM++ + K + + + D+E +G+ T L +
Sbjct: 300 MRAQNMSAYELMLSESQERMLMVLDPSKEDMARNIFKKWDLEFEVIGKVTDTKKLILMMN 359
Query: 396 EKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPE-YKEPDLNAALKAVINHHAVN 452
KE ++ L P QR P K + PE + + DL + L ++ H ++
Sbjct: 360 GKEEASIPINILVEDAPEYQRDYVIEKPSLIKKY--NPEDFNQDDLMSDLSTMLKHPDLS 417
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
S++ I YDH V TV+RP DAAV++ T K +A+S +P
Sbjct: 418 SRKWIWEQYDHMVMADTVVRP--------GSDAAVVRVHGT--NKGLAMSTDCSPVYCKH 467
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALV 572
+PY A+ E RN +A+GA P AI D G+P +PE M +E R +
Sbjct: 468 NPYEGGKHAVVETWRNLIASGALP--IAITDCMNFGNPEKPEIMGQFVECIRGMGDACSK 525
Query: 573 FKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVG 632
P +SG S NE + G + I P+ I +G++ D+ V K EG+ + +VG
Sbjct: 526 LNYPVVSGNVSLYNE---TNG--IGIYPTPAIGGVGLIKDLSNVKTLSLKNEGNFLCVVG 580
Query: 633 KPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLH---SNIMKGLVLSCHDLSEG 689
K + G S + + I E P + E K H I + L+ S HD+ EG
Sbjct: 581 KSKNHLGNSKYMTI--IQKKEDGGTPEINLD--EELKNGHFVLELINEQLIESSHDVGEG 636
Query: 690 GLAAALYEMCLSG-------IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
G+ A+ EMC++G E F+ FGE L+EIK EN
Sbjct: 637 GILIAIAEMCIAGNLGLIIDTNPEFPHGFY-----------FGEDQSRYLIEIKAEN 682
>gi|117929281|ref|YP_873832.1| phosphoribosylformylglycinamidine synthase II [Acidothermus
cellulolyticus 11B]
gi|117649744|gb|ABK53846.1| phosphoribosylformylglycinamidine synthase II [Acidothermus
cellulolyticus 11B]
Length = 754
Score = 296 bits (759), Expect = 3e-78, Method: Composition-based stats.
Identities = 238/767 (31%), Positives = 351/767 (45%), Gaps = 83/767 (10%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
R L E IRE +RP T E + WSEHC +K+ K L +
Sbjct: 19 RELGLTDDEYARIREILG--RRP-TSCELAIYSVMWSEHCSYKSSKVH-------LRQFA 68
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
+K P + D+ +++ NAG++ V+FK E+HNHPS
Sbjct: 69 EKVPP--------------SARDV----LVAGIGANAGVVRVGRGCAVTFKVESHNHPSY 110
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
+EP+ GA TGVGG++RD++ + ARP AV D L FG + P KR+ GV+
Sbjct: 111 VEPYQGAATGVGGIVRDILAMGARPVAVMDSLRFGPLEAP---------DTKRVAPGVVA 161
Query: 193 GVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG--KHRTKPSAGDHIISLGG 250
G+ YGN +G+P + G + + YA+NPLV C G+ P + + G+ ++ G
Sbjct: 162 GIGGYGNCLGLPNIGGEISFDPCYAANPLVNALCVGVLPVDGVQQASATGIGNKVVLFGA 221
Query: 251 KTGRDGLRGATFSSMVMDASTGDVAGS----SVQIGEPIIQKKVAEVLIDARDQGLYSAI 306
+TG DG+ GA+ V+ ++T D + SVQ+G+P +K + E ++ L I
Sbjct: 222 RTGGDGIGGAS----VLASATFDEHAAKRRPSVQVGDPFTEKVLIECCMELFAAHLVVGI 277
Query: 307 TDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL 364
D GA G S A E+ASA G V+L +P++ + LAP E+ +SE+QERM V + +
Sbjct: 278 QDLGAAGLSCATAELASAGSGGMRVELDAVPLRDESLAPEEILMSESQERMCAVVTPENI 337
Query: 365 EALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSC-GFLHSGPPQRKLKAAPPKD 423
++CD DV T +G T L V + + ++++ H GP R+ P +
Sbjct: 338 PRFMEICDKWDVPATIIGEVTDTGRLHVYWRGELVVDVPPRSVAHDGPVYRRPMREPAER 397
Query: 424 GKPFIKYP-EYKEPDLNAALKAVINHHAVN----SKEDIVRLYDHEVQGGTVLRPYDGPE 478
P P L+A + A + K + YD V G TV
Sbjct: 398 AVMLSDDPGRLARPTSPDQLRATVLRLAASPNLADKTWVTEQYDRYVLGNTV-------- 449
Query: 479 GNVPQDAAVIKPMETEGKK-AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPE 537
+P DA V++ + + + VA+S N R LDPY A A+ EA RN +AGA P
Sbjct: 450 AAMPDDAGVVRLTDDDAVRIGVALSLDGNGRYARLDPYVGAQLALCEAYRNVASAGARP- 508
Query: 538 KTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVS 597
A+ + G P PE MW E R + L P G SF N+ G R S
Sbjct: 509 -LAVTNCLNFGSPEDPEVMWQFAEAVRGLADGCLALDVPVTGGNVSFYNQ----TGAR-S 562
Query: 598 IPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAV 657
I P+ ++ +G++ D+ F +G +YL+G + FGGS +A + G
Sbjct: 563 IHPTPVVGVLGVLDDVTTRLRIGFSDDGDVVYLLGTTRDEFGGSEWAHVI---HGHLGGR 619
Query: 658 PPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRL 715
PP AAE L L + + LV + HDLS+GGLA AL E CL G L
Sbjct: 620 PPAVDFAAERSLAAVLVESAQRRLVHAAHDLSDGGLAQALVESCLRGW-----RGVRISL 674
Query: 716 GASKIASLFGETTGCLLVEIKEENRSAFEK--EMEGASIYEIGKTCG 760
+LF E+T +V + N + FE G IG+T G
Sbjct: 675 TGDPFVALFAESTARAVVAVAPGNVTEFEALCARHGVPAAVIGRTGG 721
>gi|91773985|ref|YP_566677.1| phosphoribosylformylglycinamidine synthase II [Methanococcoides
burtonii DSM 6242]
gi|91713000|gb|ABE52927.1| phosphoribosylformylglycinamidine synthase II [Methanococcoides
burtonii DSM 6242]
Length = 715
Score = 296 bits (758), Expect = 4e-78, Method: Composition-based stats.
Identities = 203/610 (33%), Positives = 314/610 (51%), Gaps = 44/610 (7%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
D+A II F E + ++ E+HNHPS ++P+ G+ TGVGG++RD++ + ARP A+ D L F
Sbjct: 59 DDAAIIRFGEGWVLAIGMESHNHPSYVDPYNGSATGVGGIVRDIISMGARPIALMDPLYF 118
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G +TP +N+ + +IEG+ YGN +G+P V G ++ E+Y+ NPLV C
Sbjct: 119 GPLNTP-KNL--------YLFEHIIEGIAGYGNCIGVPVVRGETYFDESYSGNPLVNVVC 169
Query: 227 AGIAPRGKHRT--KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+A T AG+ ++ +G TGRDGL GA+F+S + S+QIG+P
Sbjct: 170 VGLAREENIVTACAQKAGNKLVLIGSTTGRDGLGGASFASRDLSEEAEAEDRPSIQIGDP 229
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLA 342
+K E ++A G + D GA G + A EMAS LG ++ K+ ++ G+
Sbjct: 230 FTEKLAIEATLEAIGAGYVLSCRDLGAAGLAGASSEMASKGKLGMRLEADKVILREDGMT 289
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
P+E+ ++E+QER+++ V + ++A+ + D+ + +G T V F + + ++
Sbjct: 290 PYEIMIAESQERILMEVEPENVDAVLAIGKKYDLHASMIGELTERLYYTVEFEGEMVADI 349
Query: 403 SCGFLHSGPPQ-RKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVI----NHHAVNSKEDI 457
L G P + APP+ ++PDL A +K V+ + H + SKE I
Sbjct: 350 PVMLLTEGAPTFERPSTAPPEREIG-------EKPDLPADMKKVVLDILSSHNIASKEWI 402
Query: 458 VRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAA 517
R YDHEVQ TV +P DAAV++ + +G +A+S NPR LLDPY
Sbjct: 403 YRQYDHEVQVRTVEKP--------GSDAAVLRIGDGKG---LAMSCGCNPRHTLLDPYEG 451
Query: 518 AASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPF 577
+ E N GA E A++D G+P RP+ W + + A P
Sbjct: 452 GKGTLIENSMNLAVKGA--EGIALVDCLNFGNPERPDIYWQFKQAILGLGDAARSLSIPV 509
Query: 578 ISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFS 637
+ G S NE S +I P+ I +GI ++ VP S F EG+ I LVG
Sbjct: 510 VGGNVSLYNE---SGEYGTAIAPTPSIGLIGITGELETVPQSHFAGEGNTIILVGNTLDE 566
Query: 638 FGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
GGS + + G+ + VP E+ ++ + L + + G V++ HD+S GGLA AL E
Sbjct: 567 MGGSEYYNMVGLRL--NGNVPKVTDESVKVVETLINVVRDGNVVAAHDVSAGGLAVALSE 624
Query: 698 MCLSGIGAEL 707
MC S IGAE+
Sbjct: 625 MCDS-IGAEI 633
>gi|145222222|ref|YP_001132900.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium gilvum
PYR-GCK]
gi|145214708|gb|ABP44112.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium gilvum
PYR-GCK]
Length = 781
Score = 296 bits (758), Expect = 4e-78, Method: Composition-based stats.
Identities = 237/767 (30%), Positives = 356/767 (46%), Gaps = 97/767 (12%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
R L E IRE +RP TDAE + WSEHC +K+ K + G + TE+
Sbjct: 22 RELGLKDDEYERIREILG--RRP-TDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTEKM 78
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
++ +L+ +NAG+++ + + +FK E+HNHPS
Sbjct: 79 REI-------------------------MLAGIGENAGVVDIGDGWAATFKVESHNHPSY 113
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
IEP+ GA TGVGG++RD+M + ARP AV D L FG D P +R++ GV+
Sbjct: 114 IEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTRRVLDGVVR 164
Query: 193 GVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG--KHRTKPSAGDHIISLGG 250
G+ YGN +G+P + G + +YA NPLV C G+ + K AG+ II G
Sbjct: 165 GIGGYGNSLGLPNIGGETIFDASYAGNPLVNALCVGVLRKEDLKLAFASGAGNKIILFGA 224
Query: 251 KTGRDGLRGATFSSMVMDASTGDVAGS-------------------SVQIGEPIIQKKVA 291
+TG DG+ G S + + GD +G+ SVQ+G+P +K +
Sbjct: 225 RTGLDGIGGV--SVLASETFGGDESGAGGHEAGGGAGPSRSRKKLPSVQVGDPFTEKVLI 282
Query: 292 EVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLS 349
E ++ L I D G G S A E+ASA G V+L ++P++ + P E+ S
Sbjct: 283 ECCLELYAADLVVGIQDLGGAGLSCATSELASAGDGGMRVELEQVPLRAANMTPAEILSS 342
Query: 350 EAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSC----- 404
E+QERM V + ++A ++C DV T +G T L + + + ++++
Sbjct: 343 ESQERMCAVVTPENVDAFMEVCRKWDVLATVIGEVTDSGRLEITWHGETVVDVPPRTVAH 402
Query: 405 -GFLHSGPPQR-KLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYD 462
G ++ P QR + A D + P E +L A L A++ + S+ I YD
Sbjct: 403 EGPVYERPVQRPDTQDALIADTSASLPRPATGE-ELRATLLAMVGSPHLCSRAFITEQYD 461
Query: 463 HEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAI 522
V+G TVL Y D V++ E G + +AIS + R LDPYA A A+
Sbjct: 462 RYVRGNTVLAEY--------ADGGVLRVDEQTG-RGIAISTDASGRYTALDPYAGAQLAL 512
Query: 523 DEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKD 582
EA RN GA P A+ + G P P MW + R + A P G
Sbjct: 513 AEAYRNVAVTGATP--VAVTNCLNFGSPEDPGVMWQFSQAVRGLADGAAALGIPVTGGNV 570
Query: 583 SFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKE-GSAIYLVGKPQFSFGGS 641
SF N+ ++ +I P+ ++ +GI+ ++ R + F E G + L+G F GS
Sbjct: 571 SFYNQTGTT-----AILPTPVVGVLGILDNVSRRLPTAFGSEPGETLILLGDTHDEFDGS 625
Query: 642 VFAELFGIPSGESAAVPPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC 699
++AE + +G VPP E L + L + GLV + HD+SEGGL A+ E
Sbjct: 626 IWAE---VTAGHLGGVPPKVDLEREQLLAEVLTAASRDGLVSAAHDVSEGGLIQAVVEAA 682
Query: 700 LSG-IGAE--LKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAF 743
L+G G L E FH G LF E++G +LV + S F
Sbjct: 683 LAGETGCRIVLPEGFHD--GTGVFVFLFSESSGRVLVAVPRTEESRF 727
Score = 72.4 bits (176), Expect = 1e-10, Method: Composition-based stats.
Identities = 82/322 (25%), Positives = 136/322 (42%), Gaps = 43/322 (13%)
Query: 77 PGLCVNSIIKT----YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHP 130
P LC + I Y++ T VL+ + D G++ DE+ ++ +
Sbjct: 448 PHLCSRAFITEQYDRYVRGNT-------VLAEYAD-GGVLRVDEQTGRGIAISTDASGRY 499
Query: 131 SAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGV 190
+A++P+ GA + R+V A P AVT+ L FG P+ P G + S
Sbjct: 500 TALDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDP------GVMWQ---FSQA 550
Query: 191 IEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLVYCGCAGIAPRGKHRTKPSA-----G 242
+ G+ D +GIP G V ++ + P G GI R P+A G
Sbjct: 551 VRGLADGAAALGIPVTGGNVSFYNQTGTTAILPTPVVGVLGILDNVSRRL-PTAFGSEPG 609
Query: 243 DHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGL 302
+ +I LG D G+ ++ + + G + G ++ + ++ +AEVL A GL
Sbjct: 610 ETLILLGDT--HDEFDGSIWA----EVTAGHLGGVPPKV-DLEREQLLAEVLTAASRDGL 662
Query: 303 YSAITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVP 360
SA D GG AV E +A GC + L + + G + SE+ R+++AVP
Sbjct: 663 VSAAHDVSEGGLIQAVVEAALAGETGCRIVLPE--GFHDGTGVFVFLFSESSGRVLVAVP 720
Query: 361 NDKLEALQKLCDANDVELTNLG 382
+ +C A + T +G
Sbjct: 721 RTEESRFTAMCQARGLPATRIG 742
>gi|21222481|ref|NP_628260.1| phosphoribosylformylglycinamidine synthase subunit II [Streptomyces
coelicolor A3(2)]
gi|14916676|sp|Q9RKK5|PURL_STRCO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|5918481|emb|CAB56359.1| phosphoribosyl formylglycinamidine synthase II (EC 6.3.5.3)
[Streptomyces coelicolor A3(2)]
Length = 752
Score = 295 bits (755), Expect = 8e-78, Method: Composition-based stats.
Identities = 238/738 (32%), Positives = 355/738 (48%), Gaps = 88/738 (11%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP T AE + WSEHC +K+ K + + + +KA
Sbjct: 41 RRP-TGAELAMYSVMWSEHCSYKSSKVHL------------------------RQFGEKA 75
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
DA +L +NAG+++ + Y V+FK E+HNHPS +EP+ GA TGVGG++RD++
Sbjct: 76 PQS-DA--MLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIA 132
Query: 153 VSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGG 209
+ ARP AV D L FG HPDT KR++ GV+ G+ YGN +G+P + G
Sbjct: 133 MGARPVAVVDPLRFGAADHPDT------------KRVLPGVVAGIGGYGNCLGLPNIGGE 180
Query: 210 VHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLRGATFSSMVM 267
V + Y NPLV G G+ H K S AG+ +I G +TG DG+ GA+ ++
Sbjct: 181 VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGAS----IL 236
Query: 268 DASTGDVAGSS----VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS 323
+ T D A S VQ+G+P +K + E ++A + L I D GA G S A E+AS
Sbjct: 237 ASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELAS 296
Query: 324 --ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
+ G V L +P++ L+P E+ +SE+QERM V +K++ ++CD DV T +
Sbjct: 297 NGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLEICDKWDVIATVI 356
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAPP-KDGKPFIKYPEYKEPDLN 439
G T L + + +I+++ + H GP + A P +D + P +
Sbjct: 357 GEVTDGDRLEIFWHGGKIVDVDPRTVAHDGPVYERPYARPDWQDALQADDANKLPRPGTS 416
Query: 440 AALKA----VINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEG 495
LKA ++ SK+ I + YDH VQG TVL P+D+ +I+ ++ E
Sbjct: 417 DELKAQVLKLVGSPNQASKQWITQQYDHFVQGNTVLAQ--------PEDSGMIR-VDEES 467
Query: 496 KKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPET 555
VAI+ N R LDPY A A+ EA RN GA P A+ D G P P
Sbjct: 468 GLGVAIATDGNGRYAKLDPYTGAQLALAEAYRNVATTGAKP--LAVSDCLNFGSPEDPAV 525
Query: 556 MWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGR 615
MW E R + L TP G S N + +I P+ +++ +G++ D+ R
Sbjct: 526 MWQFAEAVRGLADGCLQLGTPVTGGNVSLYN-----QTGEAAIHPTPVVAVLGVIDDVAR 580
Query: 616 VPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLHS 673
F+++G +YL+G + FGGS ++++ G +PP E L + L S
Sbjct: 581 RTPVAFQEDGQLLYLLGDTREEFGGSAWSQVIHDHLG---GLPPKVDLERERLLGEILIS 637
Query: 674 NIMKGLVLSCHDLSEGGLAAALYEMC-LSGIGAELKEDFHTRLGASKIASLFGETTGCLL 732
G++ S HDLS+GGL A+ E L G GA L G LF E+ G +
Sbjct: 638 ASRDGMIDSAHDLSDGGLVQAVVESALLGGKGARLV----VPDGLDAFTFLFSESAGRAV 693
Query: 733 VEIKEENRSAFEKEMEGA 750
V + F +M GA
Sbjct: 694 VAVPRSEEVRF-NDMCGA 710
Score = 70.1 bits (170), Expect = 6e-10, Method: Composition-based stats.
Identities = 72/290 (24%), Positives = 123/290 (42%), Gaps = 26/290 (8%)
Query: 107 DNAGIIEFDEK--YEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+++G+I DE+ V+ + + + ++P+ GA + R+V A+P AV+D L
Sbjct: 456 EDSGMIRVDEESGLGVAIATDGNGRYAKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCL 515
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAY---ASNPL 221
FG P+ PA + + G+ D ++G P G V + A +P
Sbjct: 516 NFGSPEDPAVMWQ---------FAEAVRGLADGCLQLGTPVTGGNVSLYNQTGEAAIHPT 566
Query: 222 VYCGCAGIAPRGKHRTKPSAGD--HIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
G+ RT + + ++ L G T R+ G+ +S ++ D G +
Sbjct: 567 PVVAVLGVIDDVARRTPVAFQEDGQLLYLLGDT-REEFGGSAWSQVIHDHLGGLPPKVDL 625
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQ 339
+ ++ + E+LI A G+ + D GG AV E A G L +P
Sbjct: 626 ER-----ERLLGEILISASRDGMIDSAHDLSDGGLVQAVVESALLGGKGARLV-VP---D 676
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
GL + SE+ R V+AVP + +C A + +T +G GDAV
Sbjct: 677 GLDAFTFLFSESAGRAVVAVPRSEEVRFNDMCGARGLPVTRIGVVDGDAV 726
>gi|148256696|ref|YP_001241281.1| Phosphoribosylformylglycinamidine synthase II [Bradyrhizobium sp.
BTAi1]
gi|146408869|gb|ABQ37375.1| Phosphoribosylformylglycinamidine synthase II [Bradyrhizobium sp.
BTAi1]
Length = 735
Score = 295 bits (755), Expect = 8e-78, Method: Composition-based stats.
Identities = 226/676 (33%), Positives = 325/676 (48%), Gaps = 46/676 (6%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
APWV+ +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 65 APWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARP 124
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A + L FG P+ P + ++SGV+ G+ YGN G+PTV G +H Y
Sbjct: 125 IACLNALSFGAPEHPKT---------RHLVSGVVAGIGGYGNSFGVPTVGGQTRFHTRYD 175
Query: 218 SNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
N LV G+A K ++G + I+ LG KTGRDG+ GA+ +S D S+ +
Sbjct: 176 GNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGASMASAEFDDSSEE-K 234
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAK 333
+VQ+G+P +K + E ++ AI D GA G + + EM + LG D+DL
Sbjct: 235 RPTVQVGDPFAEKLLLEACLEIMAADCVIAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDA 294
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P + G++ +E+ LSE+QERM++ + +K + + + ++ +G T V+
Sbjct: 295 VPTRETGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAVVGYTTPSKRFVVK 354
Query: 394 FGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINHHA 450
G + +L L P R A+P P I E K P D+ AL+ +I
Sbjct: 355 HGGDVMADLPIKELGDEAPLYDRPHVASP---ALPVIHAREVKAPMDIIPALEKLIATPD 411
Query: 451 VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQG 510
+ SK I YDH + G TV RP DAAV++ +G K +A++ + PR
Sbjct: 412 LCSKRWIWEQYDHVILGNTVQRP--------GGDAAVVRVQ--DGPKGLALTVDVTPRYC 461
Query: 511 LLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTA 570
DPY A+ EA RN A G P AI DN G+P RPE M + +
Sbjct: 462 EADPYQGGMQAVAEAWRNITAVGGRP--LAITDNLNFGNPERPEIMGQFVGCLKGISEAC 519
Query: 571 LVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYL 630
P +SG S NE + G+ + PS I +G++ D + F+ EG AI L
Sbjct: 520 RALDFPVVSGNVSLYNE---TNGRAILPTPS--IGGVGLLDDFTKSASIAFEAEGEAILL 574
Query: 631 VGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE-LYKKLHSNIMKGLVLSCHDLSEG 689
+G+ G SV+ L + E A PP A + + + I G + HDLS+G
Sbjct: 575 IGETHGWLGQSVY--LRDVCGREEGAPPPVDLAAEKRIGDVVRGMIHAGTATAAHDLSDG 632
Query: 690 GLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEME 748
GL AL EM + SGIGA L A FGE LV + E +M
Sbjct: 633 GLLVALAEMAMASGIGARL---LAAPASIVPHAYWFGEDQARYLVTVPETEAGRVLAKMR 689
Query: 749 GASI--YEIGKTCGKA 762
GA + IG T G A
Sbjct: 690 GAGVPCTRIGTTGGSA 705
>gi|81428273|ref|YP_395273.1| Phospho ribosylformylglycinamidine synthase, synthetase domain
[Lactobacillus sakei subsp. sakei 23K]
gi|110831811|sp|Q38XW7|PURL_LACSS Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|78609915|emb|CAI54962.1| Phospho ribosylformylglycinamidine synthase, synthetase domain
[Lactobacillus sakei subsp. sakei 23K]
Length = 741
Score = 295 bits (755), Expect = 9e-78, Method: Composition-based stats.
Identities = 220/710 (30%), Positives = 330/710 (46%), Gaps = 80/710 (11%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + K +P + P VL +
Sbjct: 50 WSEHCSYKNSKPIL------------KKFP------------------TNGPHVLQGPGE 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V FKAE+HNHPSA+EP+ GA TGVGG+IRD+ + A P A+ D L FG
Sbjct: 80 GAGILDIGDGQAVVFKAESHNHPSAVEPYEGAATGVGGIIRDIFSMGATPIAILDSLRFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
+ K ++ V+ G+ YGN +GIPTV G + + Y +NPLV C
Sbjct: 140 ELNDN---------QTKYLVQEVVAGIGGYGNCIGIPTVGGEISFDPCYQANPLVNAMCV 190
Query: 228 GIAP-----RGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG 282
G+ +GK R AG+ ++ +G KTGRDG+ GATF+S A S+VQ+G
Sbjct: 191 GLIEQKDIQQGKAR---GAGNSVLYVGAKTGRDGIHGATFASDEF-AEGKATQRSAVQVG 246
Query: 283 EPIIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMASALGCD--VDLAKIPVKY 338
+P ++K + + ++ + I D GA G S+ EMA+ G +DL ++P +
Sbjct: 247 DPFMEKLLMDACLELILQHSDWLVGIQDMGAAGLVSSTAEMAAKAGTGMILDLDQVPQRE 306
Query: 339 QGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKE 398
++ +E+ LSE+QERM + V + + L D++ +G T ++ +
Sbjct: 307 TDMSAYEIMLSESQERMALCVRAGYEDQVIALFKGYDLDAVRIGEVTTKEQYQLWHQGQL 366
Query: 399 IINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEY--KEPDLNAALKAVINHHAVNSKED 456
+ +L L P A P+ F Y D A A++ + K
Sbjct: 367 VADLPVAALTDAAPVYHKDQAKPERLATFAAQAPYVPSVTDTQATWLALLKQPTIADKSS 426
Query: 457 IVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYA 516
R YD +V+ TV+ P DAAV++ T KKA+A++ N R LDP+
Sbjct: 427 FYRHYDAQVKTNTVVLP--------GSDAAVVRIRGT--KKALAMTTDCNGRYLYLDPHV 476
Query: 517 AAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTP 576
A+ EA RN VAAG P I D G+P +P W + A+ F TP
Sbjct: 477 GGQIAVAEAARNIVAAGGQP--LGITDCLNYGNPEKPAVFWEFDQSAQGIAAACETFGTP 534
Query: 577 FISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQF 636
ISG S NE+ +I P+ +I +G++ DI + DFK+ IYL+G+
Sbjct: 535 VISGNVSLYNEFNGE-----AIYPTPMIGMVGLIRDIQDITTQDFKQVDDLIYLIGETDD 589
Query: 637 SFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALY 696
++ GS ++ + E A L + I +GL+ S HDLSEGGLA AL
Sbjct: 590 NYAGSELQKMQQGTISDQLGHFSLATEKANQDLVLKA-IQQGLITSAHDLSEGGLAVALS 648
Query: 697 EMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK 745
E G+G ++ D +R LF ET +V +K N++AFE+
Sbjct: 649 EATFKQGLGYHVQVDLASR-------QLFAETQSRFIVTVKAANQAAFEQ 691
>gi|78188986|ref|YP_379324.1| Phosphoribosylformylglycinamidine synthase II [Chlorobium
chlorochromatii CaD3]
gi|110826532|sp|Q3ARU4|PURL_CHLCH Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|78171185|gb|ABB28281.1| Phosphoribosylformylglycinamidine synthase II [Chlorobium
chlorochromatii CaD3]
Length = 761
Score = 295 bits (754), Expect = 1e-77, Method: Composition-based stats.
Identities = 219/727 (30%), Positives = 344/727 (47%), Gaps = 73/727 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + WSEHC +K A ++KT ++
Sbjct: 32 RTPTITELGIFSVMWSEHCSYKNSIA------------------------VLKTLPREG- 66
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
+ S+ +NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ +
Sbjct: 67 ----GALLTSAGEENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTM 122
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P + ++ GV+ G+ DYGN G+PTV G +++
Sbjct: 123 GARPVASLNSLRFGSPKDP---------RVRYLVDGVVRGIGDYGNSFGVPTVAGDIYFE 173
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
E Y NPLV GI K T G+ ++ +G TGRDG+ GATF+S + ++
Sbjct: 174 EGYTGNPLVNAMSVGIVEHHKTVSATAYGTGNPVLIVGSSTGRDGIHGATFASEDLSEAS 233
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-------A 324
+ SVQ+G+P +K + E ++A + G + D GA G +S+ EM++
Sbjct: 234 EE-KRPSVQVGDPFAEKLLLEATLEAIETGYVVGLQDMGAAGITSSTSEMSARGIEKYGV 292
Query: 325 LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF 384
G ++DL +P++ G++ +E+ LSE+QERM+I + + ++ DV+ +G
Sbjct: 293 GGIEIDLDLVPIREAGMSAYEIMLSESQERMLIVAAKGFEDKIIEVYQKWDVQAVVIGEV 352
Query: 385 TGDAVLRVRFGEKEIINLSC--GFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAAL 442
T D +RV+ + + N+ L G P K +A K P + N
Sbjct: 353 TDDNHVRVKHQGQVVANIPAISLVLGGGAPVYKREAKEKKPETPLANMVADSTLNFNELG 412
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
A+++ + SK+ + R YD VQ T+ P G DAAVI+ T K VA+
Sbjct: 413 LALLSRPNIASKQWVYRQYDSMVQTNTLT-----PTGQT--DAAVIRIKGT--NKGVAMK 463
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
N R L+P A A+ E RN GA P AI + G+P +PE + E
Sbjct: 464 TDCNARYVYLNPLAGGKIAVAECARNIACTGARP--LAITNCLNFGNPLKPEVYFQFKES 521
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
R F TP G SF NE + G+R +I P+ +I +G++ +I + GS F
Sbjct: 522 VRGMGEACRTFNTPVTGGNVSFYNETFIA-GQRTAIYPTPMIGMIGLLDNIENLVGSTFT 580
Query: 623 KEGSAIYLVGKPQFSFGGSVFAEL-FGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVL 681
G I L+G PQ + GS + + +G P ++ AV + A+L + L + + L+
Sbjct: 581 ASGDRILLLGNPQLTLDGSEYLVMQYGTPGQDAPAVD--LEHEAQLQRLLVALAEQKLLH 638
Query: 682 SCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIA------SLFGETTGCLLVEI 735
S HD+S+GGL AL E + + E+ F L + + LF E G +++
Sbjct: 639 SAHDVSDGGLLVALAEKAM--MNQEMPLSFRVHLSNNDKSETAIQQQLFSEAQGRVVLSA 696
Query: 736 KEENRSA 742
E +A
Sbjct: 697 APEAVAA 703
>gi|20092848|ref|NP_618923.1| phosphoribosylformylglycinamidine synthase [Methanosarcina
acetivorans C2A]
gi|22096005|sp|Q8TIT6|PURL_METAC Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|19918152|gb|AAM07403.1| phosphoribosylformylglycinamidine synthase [Methanosarcina
acetivorans C2A]
Length = 715
Score = 295 bits (754), Expect = 1e-77, Method: Composition-based stats.
Identities = 216/659 (32%), Positives = 328/659 (49%), Gaps = 44/659 (6%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
D+A II+F++ Y ++ E+HNHPS ++P+ GA TG+GG++RD++ + ARP A+ D L F
Sbjct: 59 DDAAIIKFEDGYVLAIGMESHNHPSYVDPYNGAATGIGGIVRDIISMGARPIALMDPLYF 118
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G DTP + +I+G+ YGN +G+P VNG + Y+ NPLV
Sbjct: 119 GPLDTPKNLF---------LFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPLVNVVA 169
Query: 227 AGIAPRGKHRTKPS--AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ T S A + +I G TG+DGL GA+F+S + S SVQ+G+P
Sbjct: 170 VGLCKEENVTTSRSQKAENKLILAGSSTGKDGLGGASFASRDLSESAEAEDRPSVQVGDP 229
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLA 342
+K V E+ ++A ++G + D GA G A E+A+ LG + +P + +
Sbjct: 230 YTEKLVMEMTLEAIEKGYVKSCKDLGAAGLGGASSELAAKGGLGARIIADAVPQREPNMN 289
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
+E+ L+E+QERM+ V + ++A+ L D+ +G T + V FG + + ++
Sbjct: 290 AYEILLAESQERMLFEVAPEDVDAVLALVQKYDLNGAVVGYLTKEPTYTVEFGGEIVADI 349
Query: 403 SCGFLHSGPPQRKLKAAPP---KDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVR 459
FL G P + + P ++GK PE E DL A V++ + + SKE I R
Sbjct: 350 PIAFLTGGAPTCEKPSEAPTLREEGKK----PETPE-DLKVAFLKVLSSYNIASKEWIYR 404
Query: 460 LYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAA 519
YDHEVQ TV++P +D+ V++ G K +A++ PR LLDPY
Sbjct: 405 QYDHEVQLRTVVKP--------GEDSGVLR---ITGTKGIALTCGCQPRATLLDPYNGGK 453
Query: 520 SAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFIS 579
+AI E N GA+P AI++ G+P RPET W + A P +
Sbjct: 454 TAIIENSMNLAVKGAEP--LAIVNCLNFGNPERPETYWQFENAVLGLGDEARKLSIPVVG 511
Query: 580 GKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFG 639
G S NE S+ + +IPP+ I +G V +P F K+G +I LVG+ G
Sbjct: 512 GNVSLYNE---SDEFKTAIPPTPSIGMIGKVDLEIPLPSGFFAKDGDSIILVGETTPEMG 568
Query: 640 GSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC 699
GS + + SG + VP + A EL K + + G + S HDLS GG+ A L MC
Sbjct: 569 GSEYYAC--MDSGNAGMVPAVPENAPELIKAIIEAVKSGKLSSAHDLSLGGIGAGLARMC 626
Query: 700 LSGIGAELKEDFHTRLGASKIAS-LFGETTGCLLVEIKE-ENRSAFEKEMEGASIYEIG 756
S +GA K D G ++ LF E L+ I E E K++ A I ++G
Sbjct: 627 RS-MGA--KVDLSELAGETQADELLFSEAPARALLAISEPEAVREILKDVPHAVIGKVG 682
>gi|23098200|ref|NP_691666.1| phosphoribosylformylglycinamidine synthase component II
[Oceanobacillus iheyensis HTE831]
gi|67460951|sp|Q8ES96|PURL_OCEIH Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|22776425|dbj|BAC12701.1| phosphoribosylformylglycinamidine synthase component II
[Oceanobacillus iheyensis HTE831]
Length = 742
Score = 295 bits (754), Expect = 1e-77, Method: Composition-based stats.
Identities = 230/758 (30%), Positives = 357/758 (47%), Gaps = 98/758 (12%)
Query: 37 TDAEFETIAQ----------------TWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
+D EF+ I Q WSEHC +KT K + K +P
Sbjct: 24 SDEEFQRIKQILGRHPNFTETGIFSVMWSEHCSYKTSKPLL------------KKFP--- 68
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
D P VL + AG+I+ ++ V FK E+HNHPSA+EP+ GA
Sbjct: 69 ---------------TDGPHVLQGPGEGAGVIDIGDEQAVVFKIESHNHPSAVEPYQGAA 113
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG+IRDV + ARP A + L FG P K + S V+ G+ YGN
Sbjct: 114 TGVGGIIRDVFSMGARPIASLNSLRFG---------PLTNNRTKYLFSEVVAGIAGYGNC 164
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLR 258
+G+PTV G V + E+Y NPLV C G+ + +A G+ I+ G TGRDG+
Sbjct: 165 VGVPTVGGEVQFDESYEDNPLVNAMCVGLINHKDVQKGIAAGIGNTILYAGPPTGRDGIH 224
Query: 259 GATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAV 318
GATF+S + A + +VQ+G+P ++K + E ++ I D GA G +S+
Sbjct: 225 GATFASDDL-AEDSNKDRPAVQVGDPFMEKLLIEACLEVIQSDALVGIQDMGAAGLTSSA 283
Query: 319 GEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDV 376
EMAS G +++L +P + QG+ +E+ LSE+QERM++ V + + + + + +
Sbjct: 284 SEMASKAGTGLEMNLDLVPQREQGMTAYEMMLSESQERMLLCVQAGREQEIIDIFEKYGL 343
Query: 377 ELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPF----IKYPE 432
+ +G+ + V R++ ++ + ++ L P + + + F I P
Sbjct: 344 KSVPVGKVIEEKVFRIKHLDEVVADIPVDSLADDAPVYNMPSKEAAYYRAFQQMDIATPA 403
Query: 433 YKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPME 492
+ D LK ++ + +KE + YD VQ TV+ P DAAV++
Sbjct: 404 IE--DYANTLKQLLQQPTIANKEWVYDQYDSMVQTNTVVTP--------GSDAAVVRIKG 453
Query: 493 TEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNR 552
TE KA+A++ N R LDP A+ EA RN V +GA P + D G+P
Sbjct: 454 TE--KALAMTTDCNSRYIYLDPETGGKIAVAEAARNIVCSGAKP--LGLTDGLNFGNPTN 509
Query: 553 PETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPD 612
PE W + + TP ISG S N+ S+GK SI P+ ++ +G+
Sbjct: 510 PEIFWQMEKSVEGMSAACDALHTPVISGNVSLYNQ---SKGK--SIYPTPIVGMVGLHES 564
Query: 613 IGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF--KKEAAELYKK 670
+ S F+++ IY +G+ + FGGS L+ SG+ P AE +K
Sbjct: 565 TQHITPSYFQEKEDVIYCIGEAKAEFGGSELQHLY---SGKYEGKAPHIDLDVEAERQEK 621
Query: 671 LHSNIMKGLVLSCHDLSEGGLAAALYEMCLS--GIGAELKEDFHTRLGASKIASLFGETT 728
L S I +G++ S HD+SEGGLA AL E + G+GAE+ + LF E+
Sbjct: 622 LLSAIKEGIISSAHDISEGGLAIALAESLFNGQGLGAEIN------VVGDATVELFSESQ 675
Query: 729 GCLLVEIKEENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
LV + +++ +AFE A+ ++GK + L +
Sbjct: 676 SRFLVSVNKKHANAFESHFPEAA--KLGKVTDQGQLTI 711
>gi|29830681|ref|NP_825315.1| phosphoribosylformylglycinamidine synthase subunit II [Streptomyces
avermitilis MA-4680]
gi|67460939|sp|Q82FW4|PURL_STRAW Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|29607793|dbj|BAC71850.1| putative phosphoribosyl formylglycinamidine synthase II
[Streptomyces avermitilis MA-4680]
Length = 752
Score = 294 bits (753), Expect = 1e-77, Method: Composition-based stats.
Identities = 239/739 (32%), Positives = 353/739 (47%), Gaps = 90/739 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP T AE + WSEHC +K+ K + + + +KA
Sbjct: 41 RRP-TGAELAMYSVMWSEHCSYKSSKVHL------------------------RQFGEKA 75
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
DA +L +NAG+++ + Y V+FK E+HNHPS +EP+ GA TGVGG++RD++
Sbjct: 76 PQS-DA--LLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIA 132
Query: 153 VSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGG 209
+ ARP AV D L FG HPDT KR++ GV+ G+ YGN +G+P + G
Sbjct: 133 MGARPVAVVDPLRFGAADHPDT------------KRVLPGVVAGIGGYGNCLGLPNIGGE 180
Query: 210 VHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLRGATFSSMVM 267
V + Y NPLV G G+ H K S AG+ +I G +TG DG+ GA+ ++
Sbjct: 181 VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGAS----IL 236
Query: 268 DASTGDVAGSS----VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS 323
+ T D A S VQ+G+P +K + E ++A + L I D GA G S A E+AS
Sbjct: 237 ASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELAS 296
Query: 324 --ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
+ G V L +P++ L+P E+ +SE+QERM V +K++ +C+ DV T +
Sbjct: 297 NGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLAICEKWDVIATVI 356
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAPP------KDGKPFIKYPEYK 434
G T L + + +I+++ + H GP + A P D + P
Sbjct: 357 GEVTDGDRLEIYWHGGKIVDVDPRTVAHDGPVYERPYARPEWQDALQADDANKLPRPSSS 416
Query: 435 EPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETE 494
E + LK V + + SK I YDH VQG TVL P+D+ +I+ ++ E
Sbjct: 417 EELRDQVLKLVASPNQA-SKSWITSQYDHFVQGNTVLAQ--------PEDSGMIR-IDAE 466
Query: 495 GKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPE 554
VAI+ N R LDPYA A A+ EA RN GA P A+ D G P P
Sbjct: 467 SGLGVAIATDGNGRYAKLDPYAGAQLALSEAYRNVATTGAKP--LAVSDCLNFGSPEDPA 524
Query: 555 TMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIG 614
MW E R + TP G S N + V+I P+ +++ +G++ D+
Sbjct: 525 VMWQFAEAIRGLADACQQLGTPVTGGNVSLYN-----QTGEVAIHPTPVVAVLGVIDDVA 579
Query: 615 RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLH 672
R F++EG +YL+G + FGGS ++++ G +PP E L + L
Sbjct: 580 RRTPVAFQEEGQLLYLLGDTREEFGGSAWSQVVHDHLG---GLPPQVDLERERLLGEILI 636
Query: 673 SNIMKGLVLSCHDLSEGGLAAALYEMC-LSGIGAELKEDFHTRLGASKIASLFGETTGCL 731
S G++ + HDLS+GGL A+ E L G GA L G LF E+ G
Sbjct: 637 SASRDGMIDAAHDLSDGGLIQAVVESALLGGKGARLV----VPDGLDAFTFLFSESAGRA 692
Query: 732 LVEIKEENRSAFEKEMEGA 750
+V + F +M GA
Sbjct: 693 VVAVPRSEELRF-NDMCGA 710
Score = 71.2 bits (173), Expect = 3e-10, Method: Composition-based stats.
Identities = 74/290 (25%), Positives = 124/290 (42%), Gaps = 26/290 (8%)
Query: 107 DNAGIIEFDEK--YEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+++G+I D + V+ + + + ++P+ GA + R+V A+P AV+D L
Sbjct: 456 EDSGMIRIDAESGLGVAIATDGNGRYAKLDPYAGAQLALSEAYRNVATTGAKPLAVSDCL 515
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEA---YASNPL 221
FG P+ PA + I G+ D ++G P G V + A +P
Sbjct: 516 NFGSPEDPAVMWQ---------FAEAIRGLADACQQLGTPVTGGNVSLYNQTGEVAIHPT 566
Query: 222 VYCGCAGIAPRGKHRTKPSAGD--HIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
G+ RT + + ++ L G T R+ G+ +S +V D + G
Sbjct: 567 PVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDT-REEFGGSAWSQVVHD----HLGGLPP 621
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQ 339
Q+ + ++ + E+LI A G+ A D GG AV E A G L +P
Sbjct: 622 QV-DLERERLLGEILISASRDGMIDAAHDLSDGGLIQAVVESALLGGKGARLV-VP---D 676
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
GL + SE+ R V+AVP + +C A + +T +G GD+V
Sbjct: 677 GLDAFTFLFSESAGRAVVAVPRSEELRFNDMCGARGLPVTRIGVVDGDSV 726
>gi|110598338|ref|ZP_01386612.1| phosphoribosylformylglycinamidine synthase II [Chlorobium
ferrooxidans DSM 13031]
gi|110340036|gb|EAT58537.1| phosphoribosylformylglycinamidine synthase II [Chlorobium
ferrooxidans DSM 13031]
Length = 760
Score = 294 bits (752), Expect = 2e-77, Method: Composition-based stats.
Identities = 228/724 (31%), Positives = 346/724 (47%), Gaps = 75/724 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + WSEHC +K A ++KT ++
Sbjct: 32 RTPTFTELGIFSVMWSEHCSYKNSIA------------------------VLKTLPREG- 66
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
+ S+ +NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ +
Sbjct: 67 ----GALLTSAGEENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTM 122
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P H + ++ GV+ G+ DYGN G+PTV G +++
Sbjct: 123 GARPVASLNSLRFGSPKDP---------HVRYLVDGVVRGIGDYGNSFGVPTVGGEIYFE 173
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
E Y NPLV GI K T G+ ++ +G TGRDG+ GATF+S + ++
Sbjct: 174 EGYTGNPLVNAMSVGIVEHHKTVSATALGEGNPVLIVGSSTGRDGIHGATFASEDLSEAS 233
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-------A 324
D SVQ+G+P +K + E ++A G + D GA G +S+ EM++ +
Sbjct: 234 ED-KRPSVQVGDPFAEKLLLEATLEAIATGYVVGLQDMGAAGITSSTSEMSARGIEKTGS 292
Query: 325 LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF 384
G ++DL +P++ G++ +E+ LSE+QERM+I E + ++ DV +GR
Sbjct: 293 GGIEIDLDLVPIREAGMSAYEIMLSESQERMLIVAEKGFEEKIIEVYRKWDVLAIVIGRV 352
Query: 385 TGDAVLRVRFGEKEIINLSCG--FLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAAL 442
T D +LRV K + + L G P +A + K + K D A
Sbjct: 353 TSDNLLRVSQHGKVVAEIPAESLVLGGGAPVYIREAVEKRPDTAAAKLQDDKNLDFRALT 412
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
+++ + SK+ + YD VQ TV P G+ DAAVI+ T KKA+A+
Sbjct: 413 LELLSRPNIASKQWVYHQYDSMVQTNTVT-----PVGHT--DAAVIRIKGT--KKALAMK 463
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
N R L+P A+ E RN +GA P AI + G+P +PE +
Sbjct: 464 TDCNARYVYLNPAKGGRIAVAECARNIACSGAKP--LAITNCLNFGNPYKPEVYFQFKTS 521
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
VF TP G SF NE S G R +I P+ I +G++ DI + GS F
Sbjct: 522 VEGMGEACRVFNTPVTGGNVSFYNES-SIGGVRTAIYPTPTIGMIGLLDDIDNLVGSTFT 580
Query: 623 KEGSAIYLVGKPQFSFGGSVFAEL-FGIPSGESAAVPPFKKEAAELYKKLHSNIMKG-LV 680
+G AI L+G+P + GS + + +G P GE A PP + + ++L + G LV
Sbjct: 581 HQGDAILLLGEPDLTLEGSEYLVMQYGTP-GEDA--PPVDLQHEKKVQELLVALAAGKLV 637
Query: 681 LSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIA------SLFGETTGCLLVE 734
S HD+S+GGL AL E + + E F + A++ + +LF E G +L+
Sbjct: 638 HSAHDISDGGLFVALAEKAI--MNEEAPLGFSVNIEAAETSPVRIQRALFSEAQGRVLLS 695
Query: 735 IKEE 738
I E
Sbjct: 696 IAPE 699
>gi|85373938|ref|YP_458000.1| phosphoribosylformylglycinamidine synthase II [Erythrobacter
litoralis HTCC2594]
gi|84787021|gb|ABC63203.1| phosphoribosylformylglycinamidine synthase II [Erythrobacter
litoralis HTCC2594]
Length = 744
Score = 294 bits (752), Expect = 2e-77, Method: Composition-based stats.
Identities = 230/743 (30%), Positives = 353/743 (47%), Gaps = 92/743 (12%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + + K P +AP
Sbjct: 34 ELGIFSVMWSEHCSYKSSRLHL------------KKLP------------------TEAP 63
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ + + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 64 WVICGPGENAGVIDIGDGHAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVA 123
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG P+ P K ++ GV+ G+ YGN +G+PTV G ++H AY N
Sbjct: 124 NANALRFGRPEHPKM---------KHLVQGVVAGIGGYGNCVGVPTVCGETNFHPAYDGN 174
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A K + G+ I+ +G KTGRDG+ GAT +S + + D
Sbjct: 175 ILVNAMTVGVADTDKIFYSAATGVGNPIVYVGSKTGRDGIHGATMASTDFEEDS-DAKRP 233
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ AI D GA G +S+ EMA+ G +D+ K+P
Sbjct: 234 TVQVGDPFTEKLLIEACLELMATDAIVAIQDMGAAGLTSSSVEMATNGKTGIRLDMDKVP 293
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ +G+ P+E+ LSE+QERM++ + K E ++ +++ +G T + + FG
Sbjct: 294 CREEGMTPYEMMLSESQERMLMVLKPGKEEMAAEIFKKWELDFAVIGEVTDTQRMVLEFG 353
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGK------PFIKYPEYKEPDLNAALKAVINHH 449
+ + ++ G L P ++ K P P+ +P A L ++
Sbjct: 354 GEVVCDIPLGPLADEAPLYDRPTISLEEYKAWAKIAPITDAPDSADP--GADLLKLMASP 411
Query: 450 AVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQ 509
+ S+ I YD +V T+ DA V++ T KKA+AIS PR
Sbjct: 412 NLASRAWIAEQYDSQVGADTL---------QTGGDAGVVRVHGT--KKALAISTDCTPRY 460
Query: 510 GLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNT 569
DPY AI EA RN A GA P A+ + +P RPE M L+E R +
Sbjct: 461 CYADPYEGGKQAIAEAYRNLCAVGARP--LAVTNCLNFANPQRPEIMTQLVEALRGMGDA 518
Query: 570 ALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIY 629
+ P +SG S NE ++ G +I P+ I +GI+ D R+ FK G IY
Sbjct: 519 CRMLDFPIVSGNVSLYNESKATGGGS-AILPTPAIGGVGIIDDYERMMTMGFKNAGDTIY 577
Query: 630 LVGKPQF---------SFGGSVFAELFGIPSGESAAVPP----FKKEAAELYKKLHSNIM 676
LVG P+F G S++ ++ + + PP ++ A ++ +H I
Sbjct: 578 LVG-PEFWATPDPTRSHLGKSLWLDV--VHGRDEGRTPPTDLVVERNAGKI---IHELID 631
Query: 677 KGLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEI 735
GLV + HD+S+GGLA AL EM LS G GA+++++ + A++ FGE G +V +
Sbjct: 632 DGLVNAVHDVSDGGLAVALAEMALSGGTGADVEQN--SEYTAAQW--WFGEDQGRYVVTV 687
Query: 736 --KEENRSAFEKEMEGASIYEIG 756
E A K E A +IG
Sbjct: 688 PDTEALNEALSKGTENAETAQIG 710
>gi|31789372|gb|AAP58489.1| putative phosphoribosylformylglycinamidine synthase II [uncultured
Acidobacteria bacterium]
Length = 753
Score = 293 bits (751), Expect = 2e-77, Method: Composition-based stats.
Identities = 228/686 (33%), Positives = 335/686 (48%), Gaps = 52/686 (7%)
Query: 97 DAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSAR 156
+ P VL +NAG ++ + FK E+HNHPS IEP+ GA TGVGG+IRD+ + AR
Sbjct: 61 EGPRVLQGPGENAGAVDIGDGLAAVFKIESHNHPSFIEPYQGAATGVGGIIRDIFTMGAR 120
Query: 157 PFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAY 216
P A+ + L FG D P P+ +R + GV+ G+ YGN +GIPTV G + + + Y
Sbjct: 121 PIALMNSLRFGEMDGPEG--PR----TRRTVEGVVAGIAGYGNSIGIPTVGGEIAFDDRY 174
Query: 217 ASNPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGD 273
A NPLV C G+A R K SA G+ + +G KTGRDG+ GAT +S D S+ +
Sbjct: 175 AGNPLVNVFCLGLA-RADALVKGSASGIGNPVYYVGSKTGRDGIHGATMASAEFDESSAE 233
Query: 274 VAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDL 331
+VQ+G+P ++K + E ++ + D GA G + + EM S G ++D+
Sbjct: 234 -KRPAVQVGDPFMEKLLLEACLELMKTDALVGVQDMGAAGLTCSTCEMGSRGGAGIEIDV 292
Query: 332 AKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLR 391
+P + G+ P+E+ LSE+QERM++ V + ++++ D D+ ++G TGD V+R
Sbjct: 293 RHVPQRETGMTPYEIMLSESQERMLLVVKKGREAEVERIFDKWDLHAAHIGMVTGDGVMR 352
Query: 392 VRFGEKEIINLSCGFLHSGPPQRKLKAAPPK--DG-KPFIKYPEYKEPDLNAALKAVINH 448
V+ + + L P A P DG + F P AL A++
Sbjct: 353 VKDHGAVVAEIPNTALVDQAPVYDRPTARPAYLDGLQAFDPSSLPDPPRPQEALLAILGS 412
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
V SK + R YDH V+ TV+ G A V++ T +A+A+S N R
Sbjct: 413 PTVASKRWVYRQYDHMVRTNTVVLAGMG--------AGVVRVKGTS--RALALSVDGNGR 462
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
LDP A A+ EA RN AGA P NF G+P RPE MW +E
Sbjct: 463 YCYLDPRRGAMLAVAEAARNVACAGATPIGATNCLNF--GNPERPEIMWQFVEAVEGIAE 520
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
P G S NE + G+ +I P+ +I +G++ D RV F+ EG AI
Sbjct: 521 ACRALDVPITGGNVSLYNE---TNGE--AIYPTPVIGVVGVLDDAARVVARAFRGEGDAI 575
Query: 629 YLVGKPQFSFGGSVFAE-LFGIPSGESAAVPP---FKKEAAELYKKLHSNIMKGLVLSCH 684
L+G+ GGS + + + + G+ PP +EAA L L GL+ S H
Sbjct: 576 VLLGENFGELGGSEYLKAVHRMVKGQ----PPRLDLAREAA-LIALLGRAASAGLLRSAH 630
Query: 685 DLSEGGLAAALYEMCLS--GIGAELKEDFHTRLGAS------KIASLFGETTGCLLVEIK 736
D S+GG+A L E GIG + H G S I++LFGE+ +V ++
Sbjct: 631 DCSDGGVAVTLAESAFDTGGIGLTVDLPGHVAQGVSPAGAADPISTLFGESASRTVVSVR 690
Query: 737 EENRSAFEKEM--EGASIYEIGKTCG 760
E+R F + G IG+T G
Sbjct: 691 PEDRVRFLQMAVESGVPAQVIGRTGG 716
>gi|15679373|ref|NP_276490.1| phosphoribosylformylglycinamidine synthase II [Methanothermobacter
thermautotrophicus str. Delta H]
gi|6685808|sp|O27427|PURL_METTH Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|2622483|gb|AAB85851.1| phosphoribosylformylglycinamidine synthase II [Methanothermobacter
thermautotrophicus str. Delta H]
Length = 714
Score = 293 bits (751), Expect = 2e-77, Method: Composition-based stats.
Identities = 211/613 (34%), Positives = 324/613 (52%), Gaps = 50/613 (8%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
D+AG++E ++ + E+HNHPSAIEP+GGA TG+GG++RD++ + A P A+ D L F
Sbjct: 60 DDAGVVEITDELALVIGIESHNHPSAIEPYGGAGTGIGGILRDIISMGAMPVALLDSLRF 119
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G+ + + + V+ G+ DYGN++G+PTV G V + E + NPLV C
Sbjct: 120 GYLEDQKS---------RYLFEHVVRGISDYGNRVGVPTVAGEVEFDENFQLNPLVNVMC 170
Query: 227 AGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
AG+ P+ K P GD + +GG+TGRDG+ G TF+S + +S+ +VQ+G+P
Sbjct: 171 AGLVPKNDIKRGIAPRPGDVFLLMGGRTGRDGIHGVTFASEELTSSSELEDRPAVQVGDP 230
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASAL--GCDVDLAKIPVKYQGLA 342
+K V E + D+ S + D G GG + + E+ + G V L IP++ +G+
Sbjct: 231 FTKKMVMEASFEIMDEIEVSGVKDLGGGGLTCCISELVAKCDNGARVSLEAIPLREEGMT 290
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
P+E+ LSE+QERM+ + D +EA ++C ++ +G T + V E E+I
Sbjct: 291 PYEIMLSESQERMIFVMAPDDVEAAMEICRKYELPAAVIGEVTDTGRMIVE-SEGEVIAD 349
Query: 403 SCGFLHSGPPQRKLKAAPPK--DGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRL 460
L + PP + +A P+ +G+ +K+P K+ L +I+ + SK + R
Sbjct: 350 LPAKLLADPPVVEREARKPQLPEGQVEVKHPPLKD-----TLLKLISSPNIASKRWVYRQ 404
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YDHEVQ TV++P D DAAV++ +G VA++ N LDPY A+
Sbjct: 405 YDHEVQIRTVVKPGD--------DAAVLR---VDGTTGVALTVDCNSIHTKLDPYGGGAA 453
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
++ EA+RN V+ GA P I+D G+P +PE W E R + A F TP ISG
Sbjct: 454 SVGEAIRNVVSMGAWP--VCIVDCLNFGNPEKPEVFWQFRECVRGMADMAETFSTPVISG 511
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
SF NE +EG V++ PS ++ G + + + DFK EG I ++G+ G
Sbjct: 512 NVSFYNE---TEG--VTVNPSPVVGVAGKL-SLDSIKTLDFKDEGEEIVVIGETGPELGA 565
Query: 641 SVFAE-LFGIPSGESAAVPPFKKEAAEL-YKKLHSNIMKG---LVLSCHDLSEGGLAAAL 695
S + + GI G+ PP AE K I+ G V + HD S GG+A A+
Sbjct: 566 SEYLRTVHGIVDGK----PPETDLKAEFEAAKAVKEIIDGSGNKVTAVHDCSAGGIAVAV 621
Query: 696 YEMCL-SGIGAEL 707
EM + SGIGA +
Sbjct: 622 AEMAIKSGIGARI 634
>gi|90961643|ref|YP_535559.1| Phosphoribosylformylglycinamidine synthase II [Lactobacillus
salivarius subsp. salivarius UCC118]
gi|90820837|gb|ABD99476.1| Phosphoribosylformylglycinamidine synthase II [Lactobacillus
salivarius subsp. salivarius UCC118]
Length = 741
Score = 293 bits (751), Expect = 3e-77, Method: Composition-based stats.
Identities = 238/731 (32%), Positives = 352/731 (48%), Gaps = 99/731 (13%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K+ P ++K + K + P +
Sbjct: 50 WSEHCSYK------------------KSKP------VLKLFPNKNERVLQGPG------E 79
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGI++ + V FKAE+HNHPSA+EP+ GA TGVGG++RD+ + ARP A D L FG
Sbjct: 80 GAGIVDIGDNQAVVFKAESHNHPSAVEPYEGAATGVGGILRDIFSMGARPIASLDSLHFG 139
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
D K +I+ V+ G+ YGN MGIPTV G + + + YA NPLV
Sbjct: 140 EIDNA---------RTKYLINEVVAGIGGYGNCMGIPTVAGEITFDDCYAGNPLVNAMSV 190
Query: 228 GIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
GI + H K A G+ ++ +G KTGRDG+ GATF+S A + S+VQ+G+P
Sbjct: 191 GILDQ-SHIQKGQAKGIGNAVMYVGAKTGRDGIHGATFASADF-ADDKETQRSAVQVGDP 248
Query: 285 IIQKKVAEVLIDARD--QGLYSAITDCGAGGYSSAVGEMASAL--GCDVDLAKIPVKYQG 340
++K + E I+ + Q I D GA G S+ EM+S G +++L +P + +G
Sbjct: 249 FMEKLLMEACIELTNNHQDWLVGIQDMGAAGIVSSSCEMSSKANSGMELNLDMVPQREEG 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
++ +E+ LSE+QERM++ V ++KL + ++E +GR T + + +
Sbjct: 309 MSAYEIMLSESQERMLLCVKKGHENDVKKLFEDYNLEAVVIGRVTEGHDYILHHKGEVVT 368
Query: 401 NLSCGFL---------HSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAA---LKAVINH 448
N+ L PQR L K + P L++A L+A++
Sbjct: 369 NIPVSTLTDDVLEEPSEERVPQRILDN----------KNKDTWVPQLSSAKETLEALLQQ 418
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
+ SK+ YD +V+ TV+ P DA VI+ T KKA+A++ N R
Sbjct: 419 PTIASKKMFTETYDSQVRTSTVVGP--------GSDAGVIRIRGT--KKALAMTTDGNGR 468
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
L+P A+ EA N +++GA P AI D GDPN PE W L +
Sbjct: 469 FIYLNPEVGGKIAVLEAATNIISSGALP--LAITDCLNYGDPNDPEIYWELHQSINGMAE 526
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
TP ISG S NE + G+ +I P+ +I +G++ D+ R S + G +
Sbjct: 527 ACRTLDTPVISGNVSLYNE---NNGE--AIYPTAMIGMVGLIKDVYRTVPSFVQNTGDKL 581
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELY-KKLHSNIMKGLVLSCHDLS 687
YLVGK F GS +L + + + F E Y K L + +GLV S HDLS
Sbjct: 582 YLVGKTGNDFNGSELQKLLN--NKITGDLNDFDLEKVNSYLKNLLVTMEQGLVSSSHDLS 639
Query: 688 EGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKE 746
EGGL +L EM + G ++ D L LF ET G L+V + ++N +AFE E
Sbjct: 640 EGGLGVSLAEMVFGTDKGIKVSLDMKKEL-------LFSETPGRLVVSVSKDNVAAFE-E 691
Query: 747 MEGASIYEIGK 757
+ G I EIG+
Sbjct: 692 IMGEDITEIGE 702
>gi|146339784|ref|YP_001204832.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Bradyrhizobium sp. ORS278]
gi|146192590|emb|CAL76595.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Bradyrhizobium sp. ORS278]
Length = 736
Score = 293 bits (750), Expect = 3e-77, Method: Composition-based stats.
Identities = 235/740 (31%), Positives = 342/740 (46%), Gaps = 76/740 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ ++I + G
Sbjct: 31 REPTFTELGIFSAMWNEHCSYKS--SRIHLKGLP-------------------------- 62
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
APWV+ +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 63 --TKAPWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTM 120
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P+ P + ++SGV+ G+ YGN G+PTV G +H
Sbjct: 121 GARPIACLNALSFGAPEHPKT---------RHLVSGVVAGIGGYGNSFGVPTVGGQTRFH 171
Query: 214 EAYASNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV G+A K ++G + I+ LG KTGRDG+ GA+ +S D S+
Sbjct: 172 TRYDGNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGASMASAEFDDSS 231
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ AI D GA G + + EM + LG D+
Sbjct: 232 EE-KRPTVQVGDPFAEKLLLEACLEIMAADCVIAIQDMGAAGLTCSAVEMGAKGDLGVDL 290
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL +P + G++ +E+ LSE+QERM++ + +K + + + ++ +G T
Sbjct: 291 DLDSVPTRETGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAVVGYTTPSKR 350
Query: 390 LRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVI 446
V+ G + +L L P R A+P P I E K P + AL+ +I
Sbjct: 351 FVVKHGGDVMADLPIKELGDEAPLYDRPHVASP---ALPVIHAREVKAPMAIIPALEKLI 407
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
+ SK I YDH + G TV RP DAAV++ +G K +A++ +
Sbjct: 408 ATPDLCSKRWIWEQYDHVILGNTVQRP--------GGDAAVVRVQ--DGPKGLALTVDVT 457
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSC 566
PR DP+ A+ EA RN A G P AI DN G+P RPE M + +
Sbjct: 458 PRYCEADPFEGGKQAVAEAWRNITAVGGRP--LAITDNLNFGNPERPEIMGQFVGCLKGI 515
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
P +SG S NE + G+ + PS I +G++ D + FK EG
Sbjct: 516 SEACRALDFPVVSGNVSLYNE---TNGRAILPTPS--IGGVGLLDDFTKSASIAFKTEGE 570
Query: 627 AIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE-LYKKLHSNIMKGLVLSCHD 685
AI L+G+ G SV+ L + E A PP A + + + I G + HD
Sbjct: 571 AILLIGETHGWLGQSVY--LRDVCGREEGAPPPVDLAAEKRIGDVVRGMIHAGTATAAHD 628
Query: 686 LSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFE 744
LS+GGL AL EM + SGIGA L A FGE LV + E
Sbjct: 629 LSDGGLLVALAEMAMASGIGARL---LAAPASIVPHAYWFGEDQARYLVTVPETEAGRVL 685
Query: 745 KEMEGASI--YEIGKTCGKA 762
+M GA++ IG T G A
Sbjct: 686 AKMRGANVPCTRIGTTGGTA 705
Score = 58.5 bits (140), Expect = 2e-06, Method: Composition-based stats.
Identities = 67/262 (25%), Positives = 103/262 (39%), Gaps = 25/262 (9%)
Query: 134 EPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEG 193
+PF G V R++ V RP A+TD L FG+P+ P E + + G ++G
Sbjct: 464 DPFEGGKQAVAEAWRNITAVGGRPLAITDNLNFGNPERP-EIMGQ--------FVGCLKG 514
Query: 194 VKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSAGDHIISLGGKTG 253
+ + + P V+G V + ++ G TK + S+ KT
Sbjct: 515 ISEACRALDFPVVSGNVSLYNETNGRAILPTPSIGGVGLLDDFTKSA------SIAFKTE 568
Query: 254 RDG--LRGATFSSMVMDASTGDVAGSSVQIGEPI---IQKKVAEVLIDARDQGLYSAITD 308
+ L G T + DV G P+ +K++ +V+ G +A D
Sbjct: 569 GEAILLIGETHGWLGQSVYLRDVCGREEGAPPPVDLAAEKRIGDVVRGMIHAGTATAAHD 628
Query: 309 CGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL-EAL 367
GG A+ EMA A G L P + P W E Q R ++ VP + L
Sbjct: 629 LSDGGLLVALAEMAMASGIGARLLAAPAS---IVPHAYWFGEDQARYLVTVPETEAGRVL 685
Query: 368 QKLCDANDVELTNLGRFTGDAV 389
K+ AN V T +G G A+
Sbjct: 686 AKMRGAN-VPCTRIGTTGGTAL 706
>gi|83592047|ref|YP_425799.1| Phosphoribosylformylglycinamidine synthase II [Rhodospirillum
rubrum ATCC 11170]
gi|110831822|sp|Q2RWI3|PURL_RHORT Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|83574961|gb|ABC21512.1| Phosphoribosylformylglycinamidine synthase II [Rhodospirillum
rubrum ATCC 11170]
Length = 740
Score = 293 bits (750), Expect = 3e-77, Method: Composition-based stats.
Identities = 228/721 (31%), Positives = 342/721 (47%), Gaps = 94/721 (13%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ K + T+ AP
Sbjct: 42 ELGIFSVMWSEHCSYKSSKKWLKTLPTT------------------------------AP 71
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 72 WVIQGPGENAGVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVA 131
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG P P + +ISGV+ G+ YGN +G+PTV G V++H ++ N
Sbjct: 132 NLNALRFGDPSDP---------RTRHLISGVVAGIGGYGNCVGVPTVGGEVNFHASFNGN 182
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A + + G+ ++ +G KTGRDG+ GAT +S + +
Sbjct: 183 NLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEE-KRP 241
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLA--KIP 335
+VQ+G+P +K + E ++ + AI D GA G +S+ EMAS G VDLA ++P
Sbjct: 242 TVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRVP 301
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
++ +G+ P+EL LSE+QERM++ + K + + L + +++ +G T + + +
Sbjct: 302 MREEGMTPYELMLSESQERMLMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTWH 361
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNA--------ALKAVIN 447
+ + +L P L AA P+ +P+ P DL+ AL +I
Sbjct: 362 GEVVGDL---------PIDPLAAASPEYDRPWEPTPMAAAADLSGAEDTPWSEALLRLIG 412
Query: 448 HHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNP 507
V S+ I YDH V G T+ RP DAAVI+ E G K +A++ P
Sbjct: 413 CPDVASRRWIWEQYDHLVMGNTLQRP--------GGDAAVIRLDEAPG-KGLAMTTDCTP 463
Query: 508 RQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCY 567
R DP A+ EA RN A GA P AI DN G+P +P M + +
Sbjct: 464 RYVHADPVEGGKQAVAEAWRNLTAVGARP--LAITDNMNFGNPEKPRIMGQFVGACQGIS 521
Query: 568 NTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSA 627
L P +SG S NE + G+ +I P+ I +G++ ++ K G A
Sbjct: 522 EACLALDFPVVSGNVSLYNE---TNGQ--AILPTPTIGGVGVLDNVEASVSIALKAAGEA 576
Query: 628 IYLVGKPQFSFGGSVFAELF--GIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVL---- 681
I + G S G + LF I E A PP A ++ + ++GL+L
Sbjct: 577 ILVAGGFHGSTGAWLGQSLFLREILGREEGAPPPVDLAA----ERKVGDFVRGLILGASV 632
Query: 682 -SCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
+CHDLS+GGL AL EM ++G +GAEL + H G LFGE G L+ + E +
Sbjct: 633 TACHDLSDGGLLVALAEMAMAGDLGAELTLEGHPDNG-----RLFGEDQGRYLLTVAEGD 687
Query: 740 R 740
R
Sbjct: 688 R 688
>gi|28572944|ref|NP_789724.1| phosphoribosylformylglycinamidine synthase subunit II [Tropheryma
whipplei TW08/27]
gi|67460942|sp|Q83FE8|PURL_TROWT Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|67460943|sp|Q83H66|PURL_TROW8 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|28411077|emb|CAD67462.1| phosphoribosylformylglycinamidine synthase II [Tropheryma whipplei
TW08/27]
Length = 760
Score = 293 bits (749), Expect = 4e-77, Method: Composition-based stats.
Identities = 238/755 (31%), Positives = 351/755 (46%), Gaps = 95/755 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
KR T +E + WSEHC +K+ + + LTE KK
Sbjct: 51 KRSPTKSELAIYSVLWSEHCSYKSSRRHLR-QLADLTEVTKKH----------------- 92
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+L NAG+++ + +FK E+HNHPS IEPF GA TG+GG++RD++
Sbjct: 93 --------LLVGIGQNAGVVDIGGGWAAAFKIESHNHPSFIEPFQGAATGIGGIVRDIIA 144
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ A+P A+ D L FG P +R+ GV+ G+ YGN +G+P + G +
Sbjct: 145 MGAKPVALMDSLRFGAASDP---------DTQRVADGVVSGISFYGNCLGVPNIGGETAF 195
Query: 213 HEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDAS 270
Y NPLV C G+ R R ++ G+ ++ G TGRDG+ GA S + D+
Sbjct: 196 DPVYQGNPLVNVLCVGVMRRENIRLANASGPGNLVVLFGAPTGRDGIGGA--SVLASDSF 253
Query: 271 TGDVAGS--SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALG 326
T D + +VQIG+P ++K + E ++ L AI D GA G S A E+A +G
Sbjct: 254 TSDAKANRPAVQIGDPFVEKLLTECCLELYAADLVVAIQDLGAAGISCAASELAHNGRVG 313
Query: 327 CDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTG 386
+DL+ +P++ LAP E+ +SE+QERM+ V D LEA ++ + + +G
Sbjct: 314 IRLDLSAVPLRDTTLAPDEILVSESQERMMAIVHPDNLEAFFEITNRWGISGAVIGEVDN 373
Query: 387 DAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFI------KYPEYKEPD-LN 439
L V K ++ L+ L +GP + P K I + P +P L
Sbjct: 374 SQYLTVVHEGKTLVRLNPKTL-TGPSYNR----PVKKPAYLIRRSAANRLPVTNDPHLLR 428
Query: 440 AALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAV 499
+ VI+ ++ K I YD VQG T L P DA VI+ + G V
Sbjct: 429 EDILQVISCPNLSDKSVITNQYDRYVQGNTALCH--------PDDAGVIRMYKNTG---V 477
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
A+S N R LDP+A A A+ EA RN GA P A+ + G+P PE MW
Sbjct: 478 ALSCDGNSRYSYLDPHAGAQLAVAEAYRNVSVVGATP--LAVTNCLNFGNPENPEVMWQF 535
Query: 560 IEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGS 619
E R + + P G SF N+ ++GK I P+ ++ +GIV ++ + S
Sbjct: 536 RETCRGLSDACKRLEIPITGGNVSFYNQ---TDGK--DIFPTPVVGILGIVDNLTQTLTS 590
Query: 620 DFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLHSNIMK 677
+ IYL+G + FGGSV+A+ G VPP A E L L + K
Sbjct: 591 GWNAPDLFIYLLGVTRPEFGGSVWADTM---YGHIGGVPPKLDLARESRLSNLLVAGAKK 647
Query: 678 GLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIK 736
+ S HDLSEGGL A+ E CL G GA++ D T S +LF E+ +LV +
Sbjct: 648 RVFESAHDLSEGGLIQAIVESCLRHGFGADIALD--TIRATSLTEALFSESASRVLVSCR 705
Query: 737 EEN-------RSAFEKEMEGA-------SIYEIGK 757
+ R+++E + G +I EIGK
Sbjct: 706 SQEDLRDLCRRNSYEYTLIGTTRHTGELTISEIGK 740
>gi|28493761|ref|NP_787922.1| phosphoribosylformylglycinamidine synthase subunit II [Tropheryma
whipplei str. Twist]
gi|28476803|gb|AAO44891.1| phosphoribosylformylglycinamidine synthase II [Tropheryma whipplei
str. Twist]
Length = 780
Score = 293 bits (749), Expect = 4e-77, Method: Composition-based stats.
Identities = 238/755 (31%), Positives = 351/755 (46%), Gaps = 95/755 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
KR T +E + WSEHC +K+ + + LTE KK
Sbjct: 71 KRSPTKSELAIYSVLWSEHCSYKSSRRHLR-QLADLTEVTKKH----------------- 112
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+L NAG+++ + +FK E+HNHPS IEPF GA TG+GG++RD++
Sbjct: 113 --------LLVGIGQNAGVVDIGGGWAAAFKIESHNHPSFIEPFQGAATGIGGIVRDIIA 164
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ A+P A+ D L FG P +R+ GV+ G+ YGN +G+P + G +
Sbjct: 165 MGAKPVALMDSLRFGAASDP---------DTQRVADGVVSGISFYGNCLGVPNIGGETAF 215
Query: 213 HEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDAS 270
Y NPLV C G+ R R ++ G+ ++ G TGRDG+ GA S + D+
Sbjct: 216 DPVYQGNPLVNVLCVGVMRRENIRLANASGPGNLVVLFGAPTGRDGIGGA--SVLASDSF 273
Query: 271 TGDVAGS--SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALG 326
T D + +VQIG+P ++K + E ++ L AI D GA G S A E+A +G
Sbjct: 274 TSDAKANRPAVQIGDPFVEKLLTECCLELYAADLVVAIQDLGAAGISCAASELAHNGRVG 333
Query: 327 CDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTG 386
+DL+ +P++ LAP E+ +SE+QERM+ V D LEA ++ + + +G
Sbjct: 334 IRLDLSAVPLRDTTLAPDEILVSESQERMMAIVHPDNLEAFFEITNRWGISGAVIGEVDN 393
Query: 387 DAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFI------KYPEYKEPD-LN 439
L V K ++ L+ L +GP + P K I + P +P L
Sbjct: 394 SQYLTVVHEGKTLVRLNPKTL-TGPSYNR----PVKKPAYLIRRSAANRLPVTNDPHLLR 448
Query: 440 AALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAV 499
+ VI+ ++ K I YD VQG T L P DA VI+ + G V
Sbjct: 449 EDILQVISCPNLSDKSVITNQYDRYVQGNTALCH--------PDDAGVIRMYKNTG---V 497
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
A+S N R LDP+A A A+ EA RN GA P A+ + G+P PE MW
Sbjct: 498 ALSCDGNSRYSYLDPHAGAQLAVAEAYRNVSVVGATP--LAVTNCLNFGNPENPEVMWQF 555
Query: 560 IEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGS 619
E R + + P G SF N+ ++GK I P+ ++ +GIV ++ + S
Sbjct: 556 RETCRGLSDACKRLEIPITGGNVSFYNQ---TDGK--DIFPTPVVGILGIVDNLTQTLTS 610
Query: 620 DFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLHSNIMK 677
+ IYL+G + FGGSV+A+ G VPP A E L L + K
Sbjct: 611 GWNAPDLFIYLLGVTRPEFGGSVWADTM---YGHIGGVPPKLDLARESRLSNLLVAGAKK 667
Query: 678 GLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIK 736
+ S HDLSEGGL A+ E CL G GA++ D T S +LF E+ +LV +
Sbjct: 668 RVFESAHDLSEGGLIQAIVESCLRHGFGADIALD--TIRATSLTEALFSESASRVLVSCR 725
Query: 737 EEN-------RSAFEKEMEGA-------SIYEIGK 757
+ R+++E + G +I EIGK
Sbjct: 726 SQEDLRDLCRRNSYEYTLIGTTRHTGELTISEIGK 760
>gi|78044209|ref|YP_359920.1| phosphoribosylformylglycinamidine synthase II [Carboxydothermus
hydrogenoformans Z-2901]
gi|110826531|sp|Q3AD64|PURL_CARHZ Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|77996324|gb|ABB15223.1| phosphoribosylformylglycinamidine synthase II [Carboxydothermus
hydrogenoformans Z-2901]
Length = 728
Score = 293 bits (749), Expect = 4e-77, Method: Composition-based stats.
Identities = 238/776 (30%), Positives = 370/776 (47%), Gaps = 104/776 (13%)
Query: 9 LSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSL 68
++ R L E R I E+ E + E A WSEHC +K+ K +
Sbjct: 1 MAKWREMGLTDEEYRRIVEYLGREP---NEVELGMCAVMWSEHCSYKSSKIHL------- 50
Query: 69 TEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHN 128
K P P V+ +NAG+++ + ++FK E+HN
Sbjct: 51 -----KKLP------------------TRGPAVVQGPGENAGVVDIGDGLGIAFKIESHN 87
Query: 129 HPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIIS 188
HPSAIEP+ GA TGVGG+IRD+ + ARP A+ D L FG +P + + +
Sbjct: 88 HPSAIEPYQGAATGVGGIIRDIFAMGARPIALLDSLRFGKLHSP---------RVRHLFT 138
Query: 189 GVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHR--TKPSAGDHII 246
GV+ G+ YGN +GIPTV G V++ E+Y NPLV C GI K + G+ ++
Sbjct: 139 GVVAGIAGYGNCIGIPTVAGDVYFQESYEENPLVNAMCVGIVELSKLKKGVATGVGNPVL 198
Query: 247 SLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAI 306
+G TGRDG+ GATF+S + + G+ SVQ+G+P ++K + E ++A + G +
Sbjct: 199 LVGATTGRDGIHGATFASEEL-SQDGEDKRPSVQVGDPFMEKLLLEACLEALEYGHIVGM 257
Query: 307 TDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL 364
D GA G +S+ EMA+ G + L ++P++ +G+ P+E+ LSE+QERM++ V
Sbjct: 258 QDLGAAGLTSSSSEMAARGKSGIRLYLDRVPLREEGMTPYEIMLSESQERMLLVVEKGYE 317
Query: 365 EALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDG 424
+ + K+ D+ +G T + V F + + L P R L P
Sbjct: 318 DEIIKIFKKWDLNAVVVGEITDGEEIEVFFDGECVAKL---------PYRLLTEEAPVYD 368
Query: 425 KPFIKYPEYKE--------PDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRP-YD 475
+P+ + PE K D AL+ ++ + K + YDH+V TV++P Y
Sbjct: 369 RPY-RIPEIKNLQSINPAGVDCGEALRRLLQSPNIARKSYVYEQYDHQVGVNTVVKPGY- 426
Query: 476 GPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGAD 535
DAAV++ T KK +A+ N R +P A A+ E N GA
Sbjct: 427 -------SDAAVLRIKGT--KKGIAVKTDGNGRYVYHNPREGAKRAVLETALNLAVTGAK 477
Query: 536 PEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKR 595
P NF G+P +PE M +E+ + P G SF NE G++
Sbjct: 478 PLGLTNCLNF--GNPEKPEIMGQFVEVIAGMKEACEILNIPVTGGNVSFYNE----TGEK 531
Query: 596 VSIPPSLLISAMGIVPDI--GRVPGSDFKKEGSAIYLVGKPQFSFGGSVF-AELFG---I 649
+I P+ +I +G++ D+ G +P + F+ EG IYL+G+P G S F E FG +
Sbjct: 532 -AIYPTPVIGMVGLIDDLETGLIPMA-FQTEGDLIYLLGEPTGELGQSEFLKEFFGDVLV 589
Query: 650 PSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAEL 707
P VPP +E + + L +GL+ S HD+S+GGLA +L E +G +G +
Sbjct: 590 P------VPPVDLQEGRRIIELLPLLKKQGLINSAHDVSDGGLAVSLCEAAFAGELGVNI 643
Query: 708 KEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIY--EIGKTCGK 761
DF T L + LF E G ++V + E F K ++ A ++ ++G+ GK
Sbjct: 644 --DFTTSLLPQEF--LFSEKVGLVIVSVSPEKEEEFIKSVKNAGVFVLKLGRVNGK 695
>gi|68054852|ref|ZP_00539002.1| Phosphoribosylformylglycinamidine synthase II [Exiguobacterium
sibiricum 255-15]
gi|68008769|gb|EAM87993.1| Phosphoribosylformylglycinamidine synthase II [Exiguobacterium
sibiricum 255-15]
Length = 739
Score = 292 bits (747), Expect = 6e-77, Method: Composition-based stats.
Identities = 228/742 (30%), Positives = 345/742 (46%), Gaps = 107/742 (14%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +KT K + + +P P VL +
Sbjct: 52 WSEHCSYKTSKPVL------------RQFP------------------TTGPRVLQGPGE 81
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AG+++ + V FK E+HNHPSA+EP+ GA TGVGG+IRD+ + ARP A+ + L FG
Sbjct: 82 GAGVVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVGGIIRDIFSMGARPVALMNSLRFG 141
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
H TP N ++ V+ G+ YGN +GIPT+ G V + +Y NPLV C
Sbjct: 142 HLGTPRVN---------QLFEQVVAGIAGYGNCVGIPTIGGEVGFDHSYEGNPLVNAMCI 192
Query: 228 GIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ + AG+ ++ +G TGRDG+ GATF+S + T + +VQ+G+P
Sbjct: 193 GLINHEDIQKGLAKGAGNSVMYVGAATGRDGIHGATFASEDLGEDT-EAKRPAVQVGDPF 251
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
++K + E ++ + D GA G +S+ EMAS +G ++ L +P + G+
Sbjct: 252 MEKLLIEACLEIVGHPALVGMQDMGAAGLTSSSAEMASKAGMGIEMHLDDVPQRETGMTA 311
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM++ V + ++ + + ++G + VLR+ K + +
Sbjct: 312 YEMMLSESQERMLLVVERGREAEIEAIVSKWGLHAVHVGEVIDEKVLRLVHHGKIVAEV- 370
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE------------PDLNAALKAVINHHAV 451
P L P KP + P Y E D +A++ +
Sbjct: 371 --------PVDALAEEAPVYNKP-SRVPAYYEEFQAMDETLPVVEDAVETWRALLKQPTI 421
Query: 452 NSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGL 511
SK + YDH VQ TV+ P DAAVI+ T KA+A++ N R
Sbjct: 422 ASKRWVYDQYDHMVQTSTVVAP--------GSDAAVIRVRGT--NKALAMTTDCNSRFVY 471
Query: 512 LDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTAL 571
LDP+ A+ EA RN VA+GA P AI D G+P++PE W L +
Sbjct: 472 LDPFVGGQIAVAEAARNIVASGATP--LAITDCLNFGNPDKPEGFWQLQQATAGMAEACR 529
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
V +TP I G S NE S GK ++ P+ ++ +G+ + K+ G A+YL+
Sbjct: 530 VLETPVIGGNVSLYNE---SAGK--AVHPTPVVGMVGLHEQTEWITTQHVKQAGDAVYLL 584
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYK--KLHSNIMKGLVLSCHDLSEG 689
G+ FGGS EL + +S P A E + L + + GLV + HD++EG
Sbjct: 585 GETTAEFGGS---ELQYLQFEKSFGKAPHIDLAVEQERLLALQAAVQAGLVTAIHDVAEG 641
Query: 690 GLAAALYEMCLSGIGAELKEDFHTRLGASKI-----ASLFGETTGCLLVEIKEENRSAFE 744
GLA AL EM F T LG I LF E+ +V +K E +AF
Sbjct: 642 GLAVALAEMT-----------FGTTLGLDVIFDGPALHLFSESQSRFVVTVKPEQEAAFV 690
Query: 745 KEMEGASIYEIGKTCGKAGLKL 766
K+ GA Y++G + L++
Sbjct: 691 KQT-GA--YKLGYVTDQDALQI 709
>gi|85708525|ref|ZP_01039591.1| phosphoribosylformylglycinamidine synthase subunit II
[Erythrobacter sp. NAP1]
gi|85690059|gb|EAQ30062.1| phosphoribosylformylglycinamidine synthase subunit II
[Erythrobacter sp. NAP1]
Length = 747
Score = 292 bits (747), Expect = 7e-77, Method: Composition-based stats.
Identities = 227/747 (30%), Positives = 352/747 (47%), Gaps = 104/747 (13%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + ++KK + D
Sbjct: 34 ELGIFSVMWSEHCSYKS----------------------------SRLHLKKLPTEAD-- 63
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 64 WVICGPGENAGVIDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVA 123
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG PD P K ++ GV+ G+ YGN +G+PTV G ++H AY N
Sbjct: 124 NMNALRFGRPDHPKM---------KHLVQGVVAGIGGYGNCVGVPTVGGETNFHPAYDGN 174
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV GIA K + G+ I+ +G KTGRDG+ GAT +S + +
Sbjct: 175 ILVNAMTVGIADSDKIFYSAATGVGNPIVYVGSKTGRDGIHGATMASADFEED-AEAKRP 233
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ AI D GA G +S+ EMA+ G +D+ K+P
Sbjct: 234 TVQVGDPFTEKLLIEACLELMATDAIVAIQDMGAAGLTSSSVEMATNGKAGIRLDMNKVP 293
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ +G+ P+E+ LSE+QERM++ + K + + +++ +G T + + +
Sbjct: 294 CREEGMTPYEMMLSESQERMLMVLKPGKEAMAAAIFEKWELDFAVIGEVTDTQHMVLEWN 353
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE----------PDLN---AAL 442
+ + ++ G L A P+ +P++ EY E PD N A L
Sbjct: 354 GEVVCDIPLG---------PLAADAPEYDRPYLSKEEYAEWAQIAPMQDVPDTNDPGADL 404
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
++ ++S+ I YD +V T+ DA+V++ TE KA+AIS
Sbjct: 405 LKMLASPNLSSRSWIAEQYDSQVMADTI---------QTGGDASVVRVHGTE--KAIAIS 453
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
PR DPY AI EA RN + GA P A+ + +P RPE M +
Sbjct: 454 TDCTPRYVFADPYEGGKQAIAEAYRNLCSVGARP--LAVTNCLNFANPQRPEIMSQFVHA 511
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
+ P +SG S NE ++ G +I P+ I +GI+ D ++ S FK
Sbjct: 512 LEGMGDACRTLDFPIVSGNVSLYNESKATGGGS-AILPTPAIGGVGILEDASKMATSAFK 570
Query: 623 KEGSAIYLVGKPQF---------SFGGSVFAELFGIPSGESAAVPPF----KKEAAELYK 669
EG AIYL+ P+F G S++ ++ + + PP + A ++ +
Sbjct: 571 SEGDAIYLLA-PEFWAKPDPTRSHLGKSMWLDV--VKGRDEGRAPPVNLAAEYGAGQIVR 627
Query: 670 KLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETT 728
KL I GL+ + HDLS+GGLA AL EM L+G +GA+L + + G + FGE
Sbjct: 628 KL---IGAGLLSAVHDLSDGGLAVALAEMALAGDLGADLVDGYE---GYTAAQWWFGEDQ 681
Query: 729 GCLLVEIKEENRSAFEKEM-EGASIYE 754
++ + EN AF + + EG I E
Sbjct: 682 ARYVLTVSPENADAFNRMVAEGPDIPE 708
>gi|56751503|ref|YP_172204.1| phosphoribosylformylglycinamidine synthase subunit II
[Synechococcus elongatus PCC 6301]
gi|81298814|ref|YP_399022.1| phosphoribosylformylglycinamidine synthase II [Synechococcus
elongatus PCC 7942]
gi|67460758|sp|Q5N1Y6|PURL_SYNP6 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|93141303|sp|Q55041|PURL_SYNP7 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|56686462|dbj|BAD79684.1| phosphoribosylformyl glycinamidine synthetase II [Synechococcus
elongatus PCC 6301]
gi|81167695|gb|ABB56035.1| phosphoribosylformylglycinamidine synthase II [Synechococcus
elongatus PCC 7942]
Length = 777
Score = 291 bits (744), Expect = 2e-76, Method: Composition-based stats.
Identities = 211/678 (31%), Positives = 331/678 (48%), Gaps = 62/678 (9%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + ++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP A+ + L F
Sbjct: 76 ENAGVVDLGDGLHLAFKVESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIAILNSLRF 135
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G + P +R+ GV+ G+ YGN +G+PTV G V + AY NPLV
Sbjct: 136 GDLEQP---------RTRRLFHGVVSGISHYGNCVGVPTVGGEVAFDPAYNGNPLVNAMA 186
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVM-DASTGDVAGSSVQIGE 283
G+ + G+ ++ +G TGRDG+ GA+F+S + D S D +VQ+G+
Sbjct: 187 LGLMETDEIVKAGASGIGNPVLYVGSTTGRDGMGGASFASAELSDESLDD--RPAVQVGD 244
Query: 284 PIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGL 341
P ++K + E ++A G A D GA G + + EMA+ +G ++DL IPV+ G+
Sbjct: 245 PFLEKSLIEACLEAFKTGAVVAAQDMGAAGLTCSTAEMAAKGGVGVELDLDLIPVRESGM 304
Query: 342 APWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIIN 401
P+E LSE+QERM+ + + L + ++ G+ + ++R+ +
Sbjct: 305 VPYEYLLSESQERMLFVAAAGREQELIDIFHRWGLQAVVAGKIIAEPIVRIFWQGAIAAE 364
Query: 402 LSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP----------DLNAALKAVINHH 449
+ L P R+L PP + ++ + P N L +++
Sbjct: 365 IPATALSDNTPIYHRQLPDEPPAYAQQAWQWTIDQLPAATEVGCGDRSWNDLLLTLLDSP 424
Query: 450 AVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNA----- 504
+ SK + R YDH+VQ TV+ P DAAV++ G A+ SN
Sbjct: 425 TIASKRWVYRQYDHQVQNNTVVLPG-------AADAAVVRLRPQMGAAALKTSNKGVAAT 477
Query: 505 --LNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
N R L PY A +A+ EA RN GA+P A+ DN G P +P W L E
Sbjct: 478 TDCNARYCYLQPYEGAKAAVAEAARNLSCVGAEP--LAVTDNLNFGSPEKPIGYWQLAEA 535
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
R F TP G S NE L S+GK I P+ ++ +G+VP++ RV G F+
Sbjct: 536 CRGLSEACREFSTPVTGGNVSLYNETLDSDGKPQPIYPTPVVGMVGLVPNLDRVCGQGFQ 595
Query: 623 KEGSAIYLVGKP------QFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHS--- 673
G +YL+G P + S GGS E I A +PP + +L +++ +
Sbjct: 596 SVGDRLYLLGLPTQAADDRLSLGGS---EYLAIAHQTVAGLPP--RIDFDLERRVQAVCR 650
Query: 674 -NIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCL 731
I +G + S HD +EGGLA A+ E ++G +GA + + +G LF E +
Sbjct: 651 LGIHQGWIRSAHDSAEGGLAVAIAESAIAGSLGARV--NLGELVGHRPDWLLFAEGGARI 708
Query: 732 LVEIKEENRSAFEKEMEG 749
LV + + + +E E++
Sbjct: 709 LVSVDPAHVAVWEAELQA 726
>gi|15613192|ref|NP_241495.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
halodurans C-125]
gi|14916668|sp|Q9KF57|PURL_BACHD Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|10173243|dbj|BAB04348.1| phosphoribosylformylglycinamidine synthetase I [Bacillus halodurans
C-125]
Length = 743
Score = 290 bits (743), Expect = 2e-76, Method: Composition-based stats.
Identities = 226/723 (31%), Positives = 342/723 (47%), Gaps = 96/723 (13%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +K K + K +P ID VL +
Sbjct: 51 WSEHCSYKNSKVLL------------KKFP------------------IDGDKVLQGPGE 80
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
AGII+ ++ V FK E+HNHPSAIEP+ GA TGVGG++RDV + ARP ++ + L FG
Sbjct: 81 GAGIIDIGDEQAVVFKIESHNHPSAIEPYQGAATGVGGILRDVFSMGARPISLLNSLRFG 140
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
+P + + V+ G+ YGN +G+PTV G V + Y NPLV C
Sbjct: 141 ELTSP---------KVRYLFEEVVAGIAGYGNCVGVPTVGGEVQFDPCYEGNPLVNAMCV 191
Query: 228 GIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ + G+ ++ +G TGRDG+ GATF+S + ++ + +VQ+G+P
Sbjct: 192 GLIDHKDIQKGQAKGVGNTVMYVGASTGRDGIHGATFASEELSEAS-EEKRPAVQVGDPF 250
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPVKYQGLAP 343
++K + E ++ I D GA G +S+ EMAS G +++L +P + +G+ P
Sbjct: 251 MEKLLLEACLELIKSDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDHVPQREKGMTP 310
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ LSE+QERM+I V + + ++ + + +G+ T D LR+ L
Sbjct: 311 YEMMLSESQERMLIVVKKGREQEIKDIVAHWGLHAVEVGQVTDDKKLRL---------LH 361
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-------------PDLNAALKAVINHHA 450
G + + P L P KP K P Y E ++ L +++
Sbjct: 362 KGEVVADVPVDALAEDAPVYHKP-SKVPAYYEAFQSEKTQWIPTIANVKDTLLSLLQQPT 420
Query: 451 VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQG 510
+ SKE + YD+ VQ TV+ P DAAV++ T KKA+A++ N R
Sbjct: 421 IASKEWVYEQYDYMVQTNTVVSP--------GSDAAVVRIRGT--KKALAMTTDCNSRYL 470
Query: 511 LLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTA 570
LDP AI EA RN V +G P + D G+P +PE W L +
Sbjct: 471 FLDPEVGGKIAIAEAARNIVCSGGVP--LGVTDCLNYGNPEKPEIFWQLEKSTDGMSEAC 528
Query: 571 LVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYL 630
TP I G S NE + G V++ P+ +I +G++ D+G + FKK G IY+
Sbjct: 529 RELGTPVIGGNVSLYNE---TNG--VAVYPTPVIGMVGLIEDVGHITTQAFKKAGDLIYV 583
Query: 631 VGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYK--KLHSNIMKGLVLSCHDLSE 688
+G+ + FGGS EL + +GE + P A E + +L I G V S HD++E
Sbjct: 584 IGEAKAEFGGS---ELQKLVNGEISGKAPAIDLAVEKKRQEQLLEAIRAGAVASAHDIAE 640
Query: 689 GGLAAALYE-MCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEM 747
GGLA AL E M +GA++ D LF E+ LV + +E ++ FE +
Sbjct: 641 GGLAVALAESMMGEAVGADVVID------GEWTTELFAESQSRFLVSVPKEKQAIFESLV 694
Query: 748 EGA 750
E A
Sbjct: 695 EDA 697
>gi|72160562|ref|YP_288219.1| phosphoribosylformylglycinamidine synthase subunit II [Thermobifida
fusca YX]
gi|110831839|sp|Q47TL8|PURL_THEFY Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|71914294|gb|AAZ54196.1| phosphoribosylformylglycinamidine synthase II [Thermobifida fusca
YX]
Length = 765
Score = 290 bits (743), Expect = 2e-76, Method: Composition-based stats.
Identities = 225/756 (29%), Positives = 346/756 (45%), Gaps = 90/756 (11%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP T AE + WSEHC +K+ K ++ + +KA
Sbjct: 42 RRP-TSAELAIYSVMWSEHCSYKSSKVH------------------------LRQFGEKA 76
Query: 93 TD-DIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVM 151
D D+ +L +NAG+++ + Y V+FK E+HNHPS +EP GA TGVGG++RD++
Sbjct: 77 PDTDV----LLVGIGENAGVVDVGDGYAVTFKIESHNHPSYVEPHQGAATGVGGIVRDIL 132
Query: 152 GVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVH 211
+ ARP AV D L FG D P +R++ GV+ G+ YGN +G+P + G V
Sbjct: 133 SMGARPVAVMDSLRFGPADAP---------DTQRVLPGVVSGISSYGNCLGLPNIGGEVG 183
Query: 212 YHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDA 269
+ YASNPLV C G+ + ++ G+H++ G TG DG+ GA+ +
Sbjct: 184 FDAGYASNPLVNALCVGVLKHENIKLAQASGPGNHVVLFGAATGPDGIGGASVLASASFD 243
Query: 270 STGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGC 327
SVQ+G+P ++K + E ++ + L I D GA G S A E+A+ G
Sbjct: 244 EESQAKRPSVQVGDPFLEKLLIECCMELYAKDLVVGIQDLGAAGVSCATTELAAGGTGGM 303
Query: 328 DVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGD 387
++L ++P++ L P E+ +SE+QERM+ V DKL+ +C D+ + +G T
Sbjct: 304 RIELDRVPLRDPRLTPEEILMSESQERMMAIVEPDKLDEFLAVCAKWDILASVIGEVTDV 363
Query: 388 AVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAP--------PKDGKPFIKYPEYKEP--- 436
G + ++ + PP+ P P D + P
Sbjct: 364 TPEEEARGGRLVMTWRGETIVDLPPRTAADQGPVYHRPIERPADQDALLADDPAALPRPS 423
Query: 437 ---DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMET 493
+L + V+ + I YD V G TVL +P D+ +I+ E
Sbjct: 424 SDEELRDQVLRVLAAPGICDSSWITDQYDRYVMGNTVLA--------MPHDSGMIRIAE- 474
Query: 494 EGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRP 553
+ + VA++ N R LDPY A EA RN A GA P A+ + G P P
Sbjct: 475 DTDRGVALATDGNGRYTRLDPYVGTQLAYAEAYRNVAATGARP--LAVTNCLNFGSPEDP 532
Query: 554 ETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDI 613
MW E R + TP G SF N+ S+ +I P+ +I +G++ D+
Sbjct: 533 GVMWQFAEATRGLADACQALGTPVTGGNVSFYNQTGST-----AINPTPVIGVLGVIDDV 587
Query: 614 GRVPGSDFKKEG-SAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP---FKKEAAELYK 669
+ S F EG S ++L+G+ + GGS +A++ G PP EAA L +
Sbjct: 588 HKRVTSAFSAEGESVVFLLGETRLELGGSAWADVI---HGHLGGRPPQIDLDAEAA-LGR 643
Query: 670 KLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETT 728
L L++S HDLS+GGLA AL E CL G+G E+ LG +LF E+
Sbjct: 644 VLIDGAAAELLVSAHDLSDGGLAVALAESCLRGGVGCEVD------LGDDAFTALFSESA 697
Query: 729 GCLLVEIKEENRSAFEK--EMEGASIYEIGKTCGKA 762
+V ++ E+ +A G + +G G A
Sbjct: 698 ARAVVSVRPEHETALVDLCAKHGVPVRRLGTVGGSA 733
Score = 70.1 bits (170), Expect = 6e-10, Method: Composition-based stats.
Identities = 86/332 (25%), Positives = 138/332 (41%), Gaps = 45/332 (13%)
Query: 75 AYPGLCVNSIIKTYIKKATDDIDAPWVLSSFV----DNAGIIEFDEKYE--VSFKAETHN 128
A PG+C +S I TD D +V+ + V ++G+I E + V+ + +
Sbjct: 437 AAPGICDSSWI-------TDQYDR-YVMGNTVLAMPHDSGMIRIAEDTDRGVALATDGNG 488
Query: 129 HPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIIS 188
+ ++P+ G R+V ARP AVT+ L FG P+ P G + +
Sbjct: 489 RYTRLDPYVGTQLAYAEAYRNVAATGARPLAVTNCLNFGSPEDP------GVMWQ---FA 539
Query: 189 GVIEGVKDYGNKMGIPTVNGGVHYHEAYAS---NPLVYCGCAGIAPRGKHRTK---PSAG 242
G+ D +G P G V ++ S NP G G+ R + G
Sbjct: 540 EATRGLADACQALGTPVTGGNVSFYNQTGSTAINPTPVIGVLGVIDDVHKRVTSAFSAEG 599
Query: 243 DHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGL 302
+ ++ L G+T R L G+ ++ D G + G QI + + + VLID L
Sbjct: 600 ESVVFLLGET-RLELGGSAWA----DVIHGHLGGRPPQI-DLDAEAALGRVLIDGAAAEL 653
Query: 303 YSAITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVP 360
+ D GG + A+ E + +GC+VDL G + SE+ R V++V
Sbjct: 654 LVSAHDLSDGGLAVALAESCLRGGVGCEVDL--------GDDAFTALFSESAARAVVSVR 705
Query: 361 NDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
+ AL LC + V + LG G A+ V
Sbjct: 706 PEHETALVDLCAKHGVPVRRLGTVGGSALTMV 737
>gi|62423725|ref|ZP_00378883.1| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain [Brevibacterium linens BL2]
Length = 788
Score = 290 bits (743), Expect = 2e-76, Method: Composition-based stats.
Identities = 230/748 (30%), Positives = 347/748 (46%), Gaps = 88/748 (11%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E IRE +RP T AE + WSEHC +K+ K + G +TE+ KK
Sbjct: 54 EYAQIREILG--RRP-TSAELAMYSVMWSEHCSYKSSKVHLSKFGDKVTEDMKKH----- 105
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L +NAG+++ + + V+FK E+HNHPS +EP GA
Sbjct: 106 --------------------LLVGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPHQGAA 145
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDY 197
TGVGG++RD++ + ARP AV D L FG HPDT R++ GV+ G+ +Y
Sbjct: 146 TGVGGIVRDIISMGARPVAVMDQLRFGAIDHPDT------------SRVLHGVVSGISNY 193
Query: 198 GNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRD 255
GN +G+P + G + Y NPLV G+ R ++ G+ +I G +TG D
Sbjct: 194 GNSLGLPNIGGETVFDSVYQGNPLVNALAVGVMRHEDIRLANASGKGNKVILFGARTGGD 253
Query: 256 GLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYS 315
G+ GA+ + T +VQ+G+P +K + E ++ G+ I D GA G S
Sbjct: 254 GIGGASILASESFDDTKPSKRPAVQVGDPFAEKVLIECCLELFHAGVVEGIQDLGAAGIS 313
Query: 316 SAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDA 373
A E+AS G + L + ++ + L P E+ +SE+QERM+ V ++L+ +
Sbjct: 314 CATSELASNGDGGMHIALDDVLLRDETLTPEEILMSESQERMMAVVTPERLDDFLAIVGK 373
Query: 374 NDVELTNLGRFTGDAVLRVRFGEKEIINLSC-GFLHSGP--------PQRKLKAAPPKDG 424
DVE + LG T L + + I+++ H GP P + A
Sbjct: 374 WDVETSVLGEVTDSERLIIEWHGDVIVDVPPRSVAHDGPVYERPMVEPSWTAEVAANTVE 433
Query: 425 KPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQD 484
+ PE E DL + + + + SK I YD VQG T P D
Sbjct: 434 SAGLVKPESNE-DLRSTMLQLAGAPNLASKGWITSQYDKYVQGNTA--------QAFPDD 484
Query: 485 AAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDN 544
A V++ ++ E VAI+ N R LDP AA A+ EA RN AGA P A+ D
Sbjct: 485 AGVVR-VDEESGLGVAIATDANGRYCYLDPARGAALALAEAYRNVTTAGAIPR--AVTDC 541
Query: 545 FCLGDPNRPETMW----ALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPP 600
G P PE MW A+ +A +C + + P G S N + V+I P
Sbjct: 542 LNFGSPEDPEIMWQFAAAVEGLAEACQDMGI----PVTGGNVSLYN-----QTGGVAIHP 592
Query: 601 SLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF 660
+ ++ +G+ D+ R S +K+ G IYL+G + GS +A+ + +G VPP
Sbjct: 593 TPVVGVLGVFDDVTRATPSGWKEPGQTIYLLGTTEAELDGSAWAD---VTAGHLGGVPPQ 649
Query: 661 KKEAA--ELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAEL-KEDFHTRLG 716
K EL + L ++ G++ + HDLSEGGL+ AL E CL G GA + ++ R G
Sbjct: 650 YKPGTEKELGEILINSSRDGMIDAAHDLSEGGLSQALVESCLRFGTGARIWLDEVCERDG 709
Query: 717 ASKIASLFGETTGCLLVEIKEENRSAFE 744
+LF E+T +V + F+
Sbjct: 710 VDVFTALFSESTARAIVAVPRSEEVRFK 737
Score = 71.2 bits (173), Expect = 2e-10, Method: Composition-based stats.
Identities = 77/295 (26%), Positives = 122/295 (41%), Gaps = 28/295 (9%)
Query: 104 SFVDNAGIIEFDEK--YEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVT 161
+F D+AG++ DE+ V+ + + ++P GA + R+V A P AVT
Sbjct: 480 AFPDDAGVVRVDEESGLGVAIATDANGRYCYLDPARGAALALAEAYRNVTTAGAIPRAVT 539
Query: 162 DVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHE---AYAS 218
D L FG P+ P + +EG+ + MGIP G V + A
Sbjct: 540 DCLNFGSPEDP---------EIMWQFAAAVEGLAEACQDMGIPVTGGNVSLYNQTGGVAI 590
Query: 219 NPLVYCGCAGIAPRGKHRTKPSA----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
+P G G+ R PS G I LG T L G+ ++ D + G +
Sbjct: 591 HPTPVVGVLGVFD-DVTRATPSGWKEPGQTIYLLG--TTEAELDGSAWA----DVTAGHL 643
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKI 334
G Q +P +K++ E+LI++ G+ A D GG S A+ E G +
Sbjct: 644 GGVPPQY-KPGTEKELGEILINSSRDGMIDAAHDLSEGGLSQALVESCLRFGTGARIWLD 702
Query: 335 PV-KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRF-TGD 387
V + G+ + SE+ R ++AVP + + +C A +G TGD
Sbjct: 703 EVCERDGVDVFTALFSESTARAIVAVPRSEEVRFKDMCTARHFPFIRIGMTDTGD 757
>gi|21674063|ref|NP_662128.1| phosphoribosylformylglycinamidine synthase II [Chlorobium tepidum
TLS]
gi|34222898|sp|Q8KD17|PURL_CHLTE Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|21647215|gb|AAM72470.1| phosphoribosylformylglycinamidine synthase II [Chlorobium tepidum
TLS]
Length = 759
Score = 290 bits (742), Expect = 3e-76, Method: Composition-based stats.
Identities = 216/672 (32%), Positives = 328/672 (48%), Gaps = 44/672 (6%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ + ARP A D L F
Sbjct: 75 ENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTMGARPVASLDSLRF 134
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P P + ++ GV+ G+ DYGN G+PTV G +++ + Y NPLV
Sbjct: 135 GSPRDP---------RVRYLVDGVVRGIGDYGNSFGVPTVGGEIYFEDCYTGNPLVNVMS 185
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K T G+ ++ +G TGRDG+ GATF+S + ++ D SVQ+G+P
Sbjct: 186 VGLVEHHKTVSATAWGKGNPVLIVGSSTGRDGIHGATFASEDLSEASED-KRPSVQVGDP 244
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-------ALGCDVDLAKIPVK 337
+K + E ++A G + D GA G +S+ EM++ + G ++DL P +
Sbjct: 245 FAEKLLLEATLEAIATGAVVGLQDMGAAGLTSSTSEMSARGIEKTGSGGIEIDLDLTPAR 304
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
+G+ +EL LSE+QERM+I + + + DV +G+ T D +LRVR +
Sbjct: 305 EKGMTAYELMLSESQERMLIVAEKGREHEIIDVYKKWDVSAVVIGQVTDDNMLRVRHHGE 364
Query: 398 EI--INLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
+ I + L G P +A K P D A +++ + SK
Sbjct: 365 VVAEIPATSLVLGGGAPVYIREAVEKKPDTPAADLVADDSLDFKALSLQLLSRPNIASKA 424
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
+ + YD VQ TV P G DAAVI+ T KK +A+ N R L+P
Sbjct: 425 WVYQQYDSMVQTNTVT-----PAGQT--DAAVIRIKGT--KKGLAMKTDCNSRYVYLNPK 475
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKT 575
A A A+ E RN GA P A+ + G+P +PE + + +F T
Sbjct: 476 AGGAIAVAECARNIACTGAKP--LAVTNCLNFGNPYKPEVYFQFKSAVEGIGDACRMFDT 533
Query: 576 PFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQ 635
P G SF NE S G R +I P+ I +G++ +I + S F+K G AI L+G P+
Sbjct: 534 PITGGNVSFYNE-TSLGGGRTAIYPTPTIGMIGLLDNIDNLVESTFRKAGDAIVLLGAPE 592
Query: 636 FSFGGSVFAEL-FGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAA 693
S GS + + +G P +S AV +K EL L S K L+ S HD+S+GGLA
Sbjct: 593 LSLDGSEYLVMQYGTPGTDSPAVDLNHEKNLQELLVTLAS---KKLINSAHDVSDGGLAV 649
Query: 694 ALYEMCLSG----IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
L E + +G E+ + + G + LF E G +++ + A +E +
Sbjct: 650 TLAEKSIMNRERMLGFEVDLECSCKEGTAIQKQLFSEAQGRVVISVDPGRVGAVIEEADR 709
Query: 750 ASIYEIGKTCGK 761
+I G+ GK
Sbjct: 710 LNI--PGRVIGK 719
>gi|56962804|ref|YP_174530.1| phosphoribosylformylglycinamidine synthase subunit II [Bacillus
clausii KSM-K16]
gi|67460773|sp|Q5WJ86|PURL_BACSK Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|56909042|dbj|BAD63569.1| phosphoribosylformylglycinamidine synthase component II [Bacillus
clausii KSM-K16]
Length = 741
Score = 290 bits (742), Expect = 3e-76, Method: Composition-based stats.
Identities = 237/766 (30%), Positives = 352/766 (45%), Gaps = 89/766 (11%)
Query: 5 ELLALSNERRAALDIYEMRAIR--EFYKTEK---RPCTDAEFETIAQTWSEHCVHKTFKA 59
+LL S E A +Y + EF EK RP E + WSEHC +K K
Sbjct: 3 QLLEPSAETIKAERLYREMGLTDDEFALAEKIVGRPLNFTETGLFSVMWSEHCSYKNSKV 62
Query: 60 KIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE 119
+ K +P D VL + AGII+ ++
Sbjct: 63 LL------------KKFP------------------TDGENVLQGPGEGAGIIDIKDEQA 92
Query: 120 VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKG 179
V FK E+HNHPSAIEP+ GA TGVGG++RDV + ARP A+ + L FG ++
Sbjct: 93 VVFKIESHNHPSAIEPYQGAATGVGGILRDVFSMGARPVALLNSLRFGELESK------- 145
Query: 180 TLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRG--KHRT 237
K + V+ G+ YGN +G+PTV G V + Y SNPLV C G+ +
Sbjct: 146 --KVKYLFEEVVAGIAGYGNCVGVPTVGGEVQFDPCYESNPLVNAMCVGLIDHKDIQKGQ 203
Query: 238 KPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDA 297
G+ ++ +G TGRDG+ GATF+S + + D +VQ+G+P ++K + E ++
Sbjct: 204 AKGVGNTVMYVGASTGRDGIHGATFASEELSEDS-DAKRPAVQVGDPFMEKLLLEACLEV 262
Query: 298 RDQGLYSAITDCGAGGYSSAVGEMASALGC--DVDLAKIPVKYQGLAPWELWLSEAQERM 355
I D GA G S+ EMAS G +++L +P + G+ P+E+ LSE+QERM
Sbjct: 263 VQSDALIGIQDMGAAGLVSSSAEMASKAGSGIEMNLDLVPQREAGMTPYEMMLSESQERM 322
Query: 356 VIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRK 415
++ V + ++ + ++ +G T D LR+ + + ++ L P
Sbjct: 323 LLVVEKGREHEIKATFERWNLHAVEVGVVTDDRRLRLTHKGEIVADVPVDALAEDAPVYH 382
Query: 416 LKAAPP------KDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGT 469
+ P + P+I PE E N L ++ + SKE + YD+ VQ T
Sbjct: 383 KPSKVPAYFDAFQQQAPYI--PEITEA--NETLLKLLAQPTIASKEWVYEQYDYMVQTNT 438
Query: 470 VLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNA 529
V+ P DAAVI+ T KA+A++ N R +DP AI EA RN
Sbjct: 439 VVEP--------GSDAAVIRIRGT--NKALAMTTDCNSRYLYVDPEMGGKIAIAEAARNL 488
Query: 530 VAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYL 589
V +GA P + D G+P +PE W L + TP I G S NE
Sbjct: 489 VCSGAKP--LGVTDCLNYGNPEKPEIFWQLEKSTDGLSEACRELGTPVIGGNVSLYNE-- 544
Query: 590 SSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGI 649
S G ++ P+ +I +G+V D+ + FK G IY++G+ + FGGS EL +
Sbjct: 545 RSGG---AVYPTPVIGMVGLVEDVAHITTQSFKNAGDLIYVIGETKAEFGGS---ELQKM 598
Query: 650 PSGESAAVPPFKKEAAELYK--KLHSNIMKGLVLSCHDLSEGGLAAALYE-MCLSGIGAE 706
GE + P A E + +L S I +GLV S HD++EGGLA +L E M GAE
Sbjct: 599 LVGELSGKAPEIDLAVEKSRQQQLLSAIKQGLVQSAHDVAEGGLAVSLAEKMMECPFGAE 658
Query: 707 LKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASI 752
+ A LF E+ +V +K ++ FE + A +
Sbjct: 659 VSLSLSA-------AELFAESQSRFIVTVKPSDQQRFENTVLDAVV 697
>gi|111226063|ref|YP_716857.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Frankia alni ACN14a]
gi|111153595|emb|CAJ65353.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Frankia alni ACN14a]
Length = 795
Score = 290 bits (741), Expect = 4e-76, Method: Composition-based stats.
Identities = 236/739 (31%), Positives = 349/739 (47%), Gaps = 96/739 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP +DAE + WSEHC +K+ K + Q + P A
Sbjct: 74 RRP-SDAELAMYSVMWSEHCSYKSSKVHL---------RQFRDTP--------------A 109
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
TD + L +NAG+++ E V+FK E+HNHPS +EP+ GA TGVGG++RD++
Sbjct: 110 TDRL-----LVGMGENAGVVDVGEGLAVTFKIESHNHPSFVEPYQGAATGVGGIVRDILT 164
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP AV D L FG D P R + GV+ G+ YGN +G+PT+ G V +
Sbjct: 165 MGARPIAVLDPLRFGDADAP---------DTARTLPGVVAGIGGYGNCLGLPTIGGEVVF 215
Query: 213 HEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGAT-FSSMVMDA 269
YA NPLV C G+ P G+ +T + G+ ++ LG KTGRDG+ G + +S D
Sbjct: 216 DPTYAGNPLVNALCVGVMPVGRVQTSAATGVGNAVVLLGAKTGRDGIGGVSVLASATFDE 275
Query: 270 STGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA----- 324
G SVQ+G+P +K + E ++ D+GL + I D G G + A+ E +A
Sbjct: 276 GGGPARRPSVQVGDPFTEKILIESCLELFDRGLVTGIQDLGGAGLTCALTETTAAGLATG 335
Query: 325 --LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
G DVDL +P++ +A E+ SE+QERM+ V + L + L + V T +G
Sbjct: 336 QPGGMDVDLDLVPLREPSMAAHEVLASESQERMLAIVTPEALPEVLALAERWGVLATRIG 395
Query: 383 RFTGDAVLRVRFGEKEIINLSCGFL-HSGP----PQRK------LKAAPPKDGKPFIKYP 431
T L VR+ + ++++ G L GP P R+ ++A P + + P
Sbjct: 396 TVTDTGRLIVRWHGEVVVDVPPGSLADEGPVYERPLRRPADLDLVRADAPTAAR--LARP 453
Query: 432 EYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPM 491
+L L +I + S+ + YD VQ TVL P+DA V++
Sbjct: 454 T-TAAELRETLLRMIASPNLCSRAWVTDQYDRYVQAATVLAQ--------PEDAGVLRLS 504
Query: 492 ETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPN 551
E+ G +A++ N R LDP+ A A+ EA RN AAG+ P A+ + G P
Sbjct: 505 ESTG-LGIALATDGNGRYARLDPFTGAQLALAEACRNVSAAGSVP--IAVTNCLNFGSPE 561
Query: 552 RPETMWALIE----MARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAM 607
PE MW + +A C L P G SF N+ ++ I P+ +I +
Sbjct: 562 DPEVMWQFAQACAGLAEGCRRLGL----PVTGGNVSFYNQTGAA-----PIHPTPVIGVL 612
Query: 608 GIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAEL 667
G+ D+ R F EG A+ L+G+ FGGS +A + G F +E L
Sbjct: 613 GLFDDVARRTPIGFTDEGDALILLGETADEFGGSEWAWVTHRHLGGQPPAVDFAREKL-L 671
Query: 668 YKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASK--IASLF 724
+ L + G++ + HDLSEGGLA AL E CL G GA + LGA LF
Sbjct: 672 GEVLVAGSRDGMLTAAHDLSEGGLAQALVESCLRGGRGARIV------LGADADPFVELF 725
Query: 725 GETTGCLLVEIKEENRSAF 743
E+ G +V + F
Sbjct: 726 SESAGRAVVAVPRSEELRF 744
>gi|88854915|ref|ZP_01129581.1| phosphoribosylformylglycinamidine synthase subunit II [marine
actinobacterium PHSC20C1]
gi|88816076|gb|EAR25932.1| phosphoribosylformylglycinamidine synthase subunit II [marine
actinobacterium PHSC20C1]
Length = 769
Score = 289 bits (740), Expect = 5e-76, Method: Composition-based stats.
Identities = 228/758 (30%), Positives = 356/758 (46%), Gaps = 100/758 (13%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E IRE +RP T E + WSEHC +K+ K
Sbjct: 38 EYAKIREILG--RRP-TSGELAMYSVMWSEHCSYKSSK---------------------- 72
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+ ++ + KK +D++ ++ +NAG+I+ E + V+FK E+HNHPS IEPF GA
Sbjct: 73 --NYLRQFGKKVSDNMTKN-LMVGMGENAGVIDVGEGWAVTFKIESHNHPSYIEPFQGAA 129
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD++ + ARP AV D L FG D P R+ GV+ G+ YGN
Sbjct: 130 TGVGGIVRDIISMGARPVAVMDALRFGAIDNP---------DTARVAHGVVAGISFYGNC 180
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHR-----TKPSAGDHIISLGGKTGRD 255
+G+P + G ++ Y +NPLV G+ +H G+ ++ G +TG D
Sbjct: 181 LGLPNIGGETYFDSVYQANPLVNALAVGVL---RHEDLHLANARGVGNKVVLFGARTGGD 237
Query: 256 GLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYS 315
G+ GA+ + + G +VQ+G+P +K + E ++ L I D GA G S
Sbjct: 238 GIGGASILASDSFSEGGPTKRPAVQVGDPFAEKVLIECCLELFQGDLVEGIQDLGAAGIS 297
Query: 316 SAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDA 373
A E+AS G ++L K+ ++ L E+ +SE+QERM+ V +KL+ K+ +
Sbjct: 298 CATSELASNGDGGMFIELEKVLLRDPTLTAEEILMSESQERMMAIVKPEKLDGFLKVVEK 357
Query: 374 NDVELTNLGRFTGDAVLRVRFGEKEIINLSC------GFLHSGPPQ-----RKLKA---- 418
DVE + LG T L + + ++EI+N+ G ++ P + KL+A
Sbjct: 358 WDVETSVLGEVTDTGRLIINWHDEEIVNVEPRTVAIDGPVYDRPVEYPKWIDKLQADSAS 417
Query: 419 --APPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDG 476
A PKDG +L + ++ + K I YD V G T L
Sbjct: 418 GLARPKDGI-----------ELRDQMLQLLASPNLADKSWITNQYDRYVLGNTAL----- 461
Query: 477 PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADP 536
+ P DA +++ ++ E +++ N R LDPYA A A+ EA RN A GA+P
Sbjct: 462 ---SFPDDAGMVR-IDEESGLGFSVATDANGRFCQLDPYAGAQIALAEAFRNVAATGANP 517
Query: 537 EKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRV 596
A+ D G P PE MW + L + P G SF N + V
Sbjct: 518 --VAVSDCLNFGSPENPEVMWQFSRAVEGLADGCLEMEIPVTGGNVSFYN-----QTGDV 570
Query: 597 SIPPSLLISAMGIVPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESA 655
I P+ +++ +G++ D+ R+P S ++ EG+ IYL+G + GS +A G
Sbjct: 571 PIHPTPVVAVLGLIRDVAERIP-SGWQDEGNNIYLLGTTKLELDGSAWA---GTIHDHLG 626
Query: 656 AVPPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAEL-KEDF 711
+PP AAE L + + + ++ S HDL++GGLA L E + G+GA + +
Sbjct: 627 GLPPTVDLAAERRLADLIKAGNEQNIIASAHDLADGGLAQTLAESVMRFGVGARIWLGEL 686
Query: 712 HTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
R G +LF E+TG ++V I E+ F+ EG
Sbjct: 687 LERDGIDAATALFSESTGRMIVSIPREDDVKFQGLCEG 724
Score = 68.9 bits (167), Expect = 1e-09, Method: Composition-based stats.
Identities = 66/289 (22%), Positives = 124/289 (42%), Gaps = 27/289 (9%)
Query: 104 SFVDNAGIIEFDEKYEVSFKAET--HNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVT 161
SF D+AG++ DE+ + F T + ++P+ GA + R+V A P AV+
Sbjct: 462 SFPDDAGMVRIDEESGLGFSVATDANGRFCQLDPYAGAQIALAEAFRNVAATGANPVAVS 521
Query: 162 DVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPL 221
D L FG P+ P S +EG+ D +M IP G V ++ P+
Sbjct: 522 DCLNFGSPENP---------EVMWQFSRAVEGLADGCLEMEIPVTGGNVSFYNQTGDVPI 572
Query: 222 VYCGCAGIAP--RGKHRTKPSA----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
+ R PS G++I LG T + L G+ ++ + D G
Sbjct: 573 HPTPVVAVLGLIRDVAERIPSGWQDEGNNIYLLG--TTKLELDGSAWAGTIHDHLGG--L 628
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGE--MASALGCDVDLAK 333
+V + ++++A+++ +Q + ++ D GG + + E M +G + L +
Sbjct: 629 PPTVDLAA---ERRLADLIKAGNEQNIIASAHDLADGGLAQTLAESVMRFGVGARIWLGE 685
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
+ ++ G+ SE+ RM++++P + Q LC+ + +G
Sbjct: 686 L-LERDGIDAATALFSESTGRMIVSIPREDDVKFQGLCEGRNYPAIRIG 733
>gi|14916653|sp|P72644|PURL_SYNY3 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
Length = 768
Score = 289 bits (739), Expect = 6e-76, Method: Composition-based stats.
Identities = 220/682 (32%), Positives = 341/682 (50%), Gaps = 68/682 (9%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + ++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP A+ + L F
Sbjct: 72 ENAGVVDLGDGLRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIAILNSLRF 131
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G+ D A N +RI +GV++G+ YGN +G+PTV G +++ AY+ NPLV
Sbjct: 132 GNLDD-ARN--------RRIFTGVVDGISHYGNCVGVPTVGGEIYFDPAYSGNPLVNAMA 182
Query: 227 AGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSM-VMDASTGDVAGSSVQIG 282
G+ + K A G+ ++ +G TGRDG+ GA+F+S + D S D +VQ+G
Sbjct: 183 LGLM-ETEEIVKAGASGIGNPVLYVGSTTGRDGMGGASFASAELTDQSMDD--RPAVQVG 239
Query: 283 EPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQG 340
+P ++K + E ++A G A D GA G + + EMA+ +G ++DL KIPV+ G
Sbjct: 240 DPFLEKSLIEACLEAFKSGAVVAAQDMGAAGITCSTAEMAAKGGVGIELDLDKIPVRETG 299
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E LSE+QERM+ + + L + ++ G+ D ++R+ F
Sbjct: 300 MVPYEYLLSESQERMLFVAQPGREQELIDIFHRWGLQAVVAGQVIADPIVRIFFQGGIAA 359
Query: 401 NLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDL-----------------NAA 441
+ L P R+L P + + +++E DL N
Sbjct: 360 EIPATALADNTPIYHRQLLDQAPDYAQ---QAWQWQESDLSPAAIAGIEIAGQKQSWNEV 416
Query: 442 LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAV--IKPMETEGKK-- 497
L +++ + SK + R YDH+VQ TV+ P DAAV ++P++ + ++
Sbjct: 417 LLTLLDSPTIASKHWVYRQYDHQVQNNTVIVPGGA-------DAAVVRVRPLDAKPEECV 469
Query: 498 -AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM 556
VA + N R L+P A +A+ EA RN GA+P A+ DN G P P
Sbjct: 470 IGVAATTDCNARYVYLNPLEGAKAAVAEAARNLSCVGAEP--LAVTDNLNFGSPENPVGY 527
Query: 557 WALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRV 616
W L TP G S NE L S G+ I P+ +I +G V +I +V
Sbjct: 528 WQLALACEGIAEGCRQLNTPVTGGNVSLYNETLDSNGRPQPIYPTPVIGMVGRVENINKV 587
Query: 617 PGSDFKKEGSAIYLVGKPQ-FSFGGSVFAELFGIPSGESAAVPP---FKKEAAELYKKLH 672
G ++ G+ IYL+G + GGS E + A PP F E A + K
Sbjct: 588 VGQGWRNSGNGIYLLGSNDGNTLGGS---EYLAVVHHTVAGQPPQVDFDLEKA-VQKACR 643
Query: 673 SNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELK-EDFHTRLGASKIASLFGETTGC 730
I +G V + HD +EGGL+ AL EM + S +GAE+ D RL LFGE+
Sbjct: 644 HGIAQGWVNAAHDCAEGGLSVALAEMAIASQLGAEINLPDSDQRLD----NLLFGESASR 699
Query: 731 LLVEIKEENRSAFEKEMEGASI 752
++V + E++ A+E + G S+
Sbjct: 700 IVVAVAPEHQPAWENYLAGQSL 721
>gi|16329238|ref|NP_439966.1| phosphoribosylformylglycinamidine synthase subunit II
[Synechocystis sp. PCC 6803]
gi|1651718|dbj|BAA16646.1| phosphoribosylformyl glycinamidine synthetase II [Synechocystis sp.
PCC 6803]
Length = 777
Score = 289 bits (739), Expect = 6e-76, Method: Composition-based stats.
Identities = 220/682 (32%), Positives = 341/682 (50%), Gaps = 68/682 (9%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + ++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP A+ + L F
Sbjct: 81 ENAGVVDLGDGLRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIAILNSLRF 140
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G+ D A N +RI +GV++G+ YGN +G+PTV G +++ AY+ NPLV
Sbjct: 141 GNLDD-ARN--------RRIFTGVVDGISHYGNCVGVPTVGGEIYFDPAYSGNPLVNAMA 191
Query: 227 AGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSM-VMDASTGDVAGSSVQIG 282
G+ + K A G+ ++ +G TGRDG+ GA+F+S + D S D +VQ+G
Sbjct: 192 LGLM-ETEEIVKAGASGIGNPVLYVGSTTGRDGMGGASFASAELTDQSMDD--RPAVQVG 248
Query: 283 EPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQG 340
+P ++K + E ++A G A D GA G + + EMA+ +G ++DL KIPV+ G
Sbjct: 249 DPFLEKSLIEACLEAFKSGAVVAAQDMGAAGITCSTAEMAAKGGVGIELDLDKIPVRETG 308
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E LSE+QERM+ + + L + ++ G+ D ++R+ F
Sbjct: 309 MVPYEYLLSESQERMLFVAQPGREQELIDIFHRWGLQAVVAGQVIADPIVRIFFQGGIAA 368
Query: 401 NLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDL-----------------NAA 441
+ L P R+L P + + +++E DL N
Sbjct: 369 EIPATALADNTPIYHRQLLDQAPDYAQ---QAWQWQESDLSPAAIAGIEIAGQKQSWNEV 425
Query: 442 LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAV--IKPMETEGKK-- 497
L +++ + SK + R YDH+VQ TV+ P DAAV ++P++ + ++
Sbjct: 426 LLTLLDSPTIASKHWVYRQYDHQVQNNTVIVPGGA-------DAAVVRVRPLDAKPEECV 478
Query: 498 -AVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM 556
VA + N R L+P A +A+ EA RN GA+P A+ DN G P P
Sbjct: 479 IGVAATTDCNARYVYLNPLEGAKAAVAEAARNLSCVGAEP--LAVTDNLNFGSPENPVGY 536
Query: 557 WALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRV 616
W L TP G S NE L S G+ I P+ +I +G V +I +V
Sbjct: 537 WQLALACEGIAEGCRQLNTPVTGGNVSLYNETLDSNGRPQPIYPTPVIGMVGRVENINKV 596
Query: 617 PGSDFKKEGSAIYLVGKPQ-FSFGGSVFAELFGIPSGESAAVPP---FKKEAAELYKKLH 672
G ++ G+ IYL+G + GGS E + A PP F E A + K
Sbjct: 597 VGQGWRNSGNGIYLLGSNDGNTLGGS---EYLAVVHHTVAGQPPQVDFDLEKA-VQKACR 652
Query: 673 SNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELK-EDFHTRLGASKIASLFGETTGC 730
I +G V + HD +EGGL+ AL EM + S +GAE+ D RL LFGE+
Sbjct: 653 HGIAQGWVNAAHDCAEGGLSVALAEMAIASQLGAEINLPDSDQRLD----NLLFGESASR 708
Query: 731 LLVEIKEENRSAFEKEMEGASI 752
++V + E++ A+E + G S+
Sbjct: 709 IVVAVAPEHQPAWENYLAGQSL 730
>gi|49475724|ref|YP_033765.1| phosphoribosylformylglycinamidine synthase subunit II [Bartonella
henselae str. Houston-1]
gi|67460815|sp|Q6G335|PURL_BARHE Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|49238531|emb|CAF27767.1| Phosphoribosylformylglycinamidine synthase II [Bartonella henselae
str. Houston-1]
Length = 735
Score = 288 bits (738), Expect = 8e-76, Method: Composition-based stats.
Identities = 224/738 (30%), Positives = 353/738 (47%), Gaps = 72/738 (9%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ K +KT K
Sbjct: 33 REPTFTELGIFSAMWNEHCSYKSSK------------------------KWLKTLPTKGN 68
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
I P +NAG+++ E V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 69 CVIQGPG------ENAGVVDIGEGQCVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTM 122
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG PD P + +++GV+ G+ Y N G+PTV G +++
Sbjct: 123 GARPIAAMNALRFGSPDHP---------RTRYLVAGVVSGIGGYSNAFGVPTVGGEINFD 173
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
E Y N LV AGIA + + G ++ LG KTGRDG+ GAT +S D S
Sbjct: 174 ERYNGNILVNAFVAGIAKKDSIFYSKAQGVGLPVVYLGAKTGRDGVGGATMASAEFDDSI 233
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ + G AI D GA G +S+ EM + LG +
Sbjct: 234 SE-KRPTVQVGDPFTEKCLLEACLELMELGAVVAIQDMGAAGLTSSAVEMGAKGDLGIKL 292
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L K+PV+ + + +E+ LSE+QERM++ + + + + + + +G+ T D
Sbjct: 293 NLDKVPVREENMTAYEMMLSESQERMLMVLKPELEKQASAIFHKWGLHFSIIGQTTDDLR 352
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE-PDLNAALKAVINH 448
RV +E++NL L + P + P +P +K E K+ +L L ++N
Sbjct: 353 FRVLHQGEEVVNLPIKELGNEAPVYDRPWSEPTP-QPILKVEEVKKVENLGDVLLTLLNS 411
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
+S+ + YD +QG T++RP DA VI+ + + K+A+A S+ + PR
Sbjct: 412 AHQSSRRWVYEQYDTLIQGNTLVRP--------GADAGVIR-VSSNDKRALAFSSDVTPR 462
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
DPY A+ E RN GA P A DN G+P +PE M L+ +
Sbjct: 463 YCEADPYEGGKQAVAECWRNISTTGAMP--LAATDNLNFGNPEKPEIMGQLVLAIKGIGE 520
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
V P +SG S NE + G+ +I P+ I+ +G++ D ++ + G +I
Sbjct: 521 ACRVLDFPIVSGNVSLYNE---TNGE--AILPTPTIAGVGLLDDWSKMVTISGMQNGDSI 575
Query: 629 YLVGKPQFSFGGSVFAE-LFGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDL 686
L+G G S++A + I +G V +K+ + + + I +G V + HD+
Sbjct: 576 VLIGDCGSHLGQSIYARNVLNINTGAPPHVDLQLEKKHGQFVRDV---IHRGFVHAAHDI 632
Query: 687 SEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK- 745
S+GGLA AL EM + +K RL A LFGE G L+ IK + ++
Sbjct: 633 SDGGLAIALAEM-VIKAKKGIKAKLSNRLPHH--AELFGEDQGRYLLSIKPYVLNHLKEL 689
Query: 746 -EMEGASIYEIGKTCGKA 762
++ S+ EIG+ G +
Sbjct: 690 AQVNAVSLTEIGRVEGNS 707
>gi|46199457|ref|YP_005124.1| phosphoribosylformylglycinamidine synthase [Thermus thermophilus
HB27]
gi|55981488|ref|YP_144785.1| phosphoribosylformylglycinamidine synthase II [Thermus thermophilus
HB8]
gi|67460770|sp|Q5SMH8|PURL_THET8 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|67460900|sp|Q72IH7|PURL_THET2 Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|46197083|gb|AAS81497.1| phosphoribosylformylglycinamidine synthase [Thermus thermophilus
HB27]
gi|55772901|dbj|BAD71342.1| phosphoribosylformylglycinamidine synthase II [Thermus thermophilus
HB8]
Length = 725
Score = 288 bits (738), Expect = 8e-76, Method: Composition-based stats.
Identities = 231/749 (30%), Positives = 353/749 (47%), Gaps = 82/749 (10%)
Query: 26 REFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSII 85
RE + R E WSEHC +K + + KA P
Sbjct: 16 REIVQRLGREPNRVELLLFKVMWSEHCAYKNSRPLL------------KALPK------- 56
Query: 86 KTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGG 145
+ VL +NAG++ E + V+FK E+HNHPSA+EPF GA TGVGG
Sbjct: 57 -----------EGEAVLQGPGENAGVVRVGEGWAVAFKIESHNHPSAVEPFQGAATGVGG 105
Query: 146 VIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPT 205
++RD+M + ARP A+ D L FG P+ + ++ GV+ G+ YGN +G+PT
Sbjct: 106 ILRDIMSMGARPIALLDSLRFGPPEEA---------RSRYLLKGVVSGIAFYGNAIGVPT 156
Query: 206 VNGGVHYHEAYASNPLVYCGCAGIAPRGKH--RTKPSAGDHIISLGGKTGRDGLRGATFS 263
V G +++HE Y NPLV C G+ R +H R++ S G I G KTGRDG+ GA F+
Sbjct: 157 VGGDLYFHEGYRENPLVNAMCLGLL-REEHLKRSRASLGRPIYYAGAKTGRDGIGGAAFA 215
Query: 264 SMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA- 322
S + + +VQ+G+P + K + E ++A + L + D GA G +S++ E+A
Sbjct: 216 SRELKEEKAE-DRPAVQVGDPFLGKLLMEATLEAIELDLVEGVQDMGAAGLTSSLSELAH 274
Query: 323 -SALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
S LG ++ L +P + +G+ P EL LSE+QERMV+ K +AL+++ ++ +
Sbjct: 275 KSGLGVELHLDLVPTREEGMTPEELLLSESQERMVLVPKEGKEKALEEVFGRWGLDCVPV 334
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAA 441
R + V RV F + + + L P ++ P+ + E D
Sbjct: 335 ARTIPERVFRVLFRGEVVAEVPTEALAEAPTYVRVGREDPEVRRLRETPIPPLEADPQEV 394
Query: 442 LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAI 501
L+ ++ + S+E + YDH+V T L P G DAAV+ T + VA
Sbjct: 395 LRRLLASPNLASREAVYERYDHQVGTRTALLPGKG-------DAAVLWIKGT--RLGVAA 445
Query: 502 SNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIE 561
NPR L P A A+ EA RN GA P A D LG P PE L E
Sbjct: 446 KVDQNPRYSRLHPRLGAMHALAEACRNVSVVGAKP--LAYTDGLNLGSPETPEGYHELAE 503
Query: 562 MARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDF 621
+ P +SG S NE S GKR IPP+ ++ +G++ ++ + F
Sbjct: 504 TIAGLKEASEALGVPVVSGNVSLYNE---SGGKR--IPPTAMVGVVGVL-EVDKRAEMGF 557
Query: 622 KKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP---FKKEAAELYKKLHSNIMKG 678
++ G + L+G+ + G S E+ + +G+ PP +E A + + + I +G
Sbjct: 558 RRPGEVLLLIGEERGELGAS---EVLYLLTGKEFGHPPRLDLGREKA-VQEAIRDLIQRG 613
Query: 679 LVLSCHDLSEGGLAAALYEMCLS-GIGA--ELKEDFHTRLGASKIASLFGETTGCLL--V 733
L + HD++EGGL AL EM G+GA E++E+ + +LFGE +L V
Sbjct: 614 LTRTAHDVAEGGLLLALAEMTFPYGVGATVEVREE--------GLEALFGEAPSRVLFTV 665
Query: 734 EIKEENRSAFEKEMEGASIYEIGKTCGKA 762
E + E G +G+T GK+
Sbjct: 666 EKTRLQEATLLLEERGLPYRVLGETGGKS 694
>gi|15606878|ref|NP_214258.1| phosphoribosylformylglycinamidine synthase II [Aquifex aeolicus
VF5]
gi|14916650|sp|O67691|PURL_AQUAE Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|2984116|gb|AAC07653.1| phosphoribosylformylglycinamidine synthase II [Aquifex aeolicus
VF5]
Length = 745
Score = 288 bits (737), Expect = 1e-75, Method: Composition-based stats.
Identities = 226/762 (29%), Positives = 367/762 (48%), Gaps = 83/762 (10%)
Query: 26 REFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSII 85
R+ KT KR E + WSEHC +K+ K + K +P
Sbjct: 16 RKILKTLKREPNHVELGVLGALWSEHCSYKSSKKHL------------KKFP-------- 55
Query: 86 KTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGG 145
A WV+ +NAG+++ DEK V+FK E+HNHPS IEPF GA TGVGG
Sbjct: 56 ----------TKAEWVVQGPGENAGVVKIDEKVWVAFKVESHNHPSYIEPFHGAATGVGG 105
Query: 146 VIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPT 205
+IRDV+ + ARP A+ D L FG + KR++ GV+ G+ YGN +G+PT
Sbjct: 106 IIRDVLSMGARPIALADSLRFGEFNYH---------ETKRLVKGVVSGISFYGNCIGVPT 156
Query: 206 VNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLRGATFS 263
V G + +Y +NPLV C G+ P G+ +R + + G + +G TGRDG+ GA +
Sbjct: 157 VAGETVFEPSYKTNPLVNAFCLGVIPAGRMYRARATREGQLLFLIGSSTGRDGIFGAVMA 216
Query: 264 SMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA- 322
S + +VQIG+P KK+ E +++ ++ L + D GA G + + E+A
Sbjct: 217 SGEFSEDVEE-KRPNVQIGDPYFGKKLVEAIMEIVEKDLIVGMQDLGAAGLAGSASEIAA 275
Query: 323 -SALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
S G ++ L +P++ + + P+E+ LSE+QERM++ V + +E ++++ + +E +
Sbjct: 276 KSEKGVELYLENVPLREKDMNPYEILLSESQERMLLVVEEENVEKVKEIANKWHLEGAVV 335
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP--DLN 439
G+ T D R + + + L + P P+ K + + + P D+
Sbjct: 336 GKITDDDTFRAYYKGELVAELPVSLIVDEAPVYDRPYKEPEYMKEVRNFNQEELPQTDVK 395
Query: 440 AALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAV 499
ALK +++ ++ KE + YD++V T+L P G + V + V++P E +K +
Sbjct: 396 EALKKLLSSPNISCKEWVYTQYDYQVGTNTLLIP--GHDAAVLRLKWVLRP-ELTTEKGI 452
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
AIS+ N R L+PY + E RN GA P AI D G+P RPE MW
Sbjct: 453 AISSEGNGRMVYLNPYEGGKFVVAEVCRNLACVGAKP--LAITDCLNFGNPERPEIMWQF 510
Query: 560 IE----MARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGR 615
++ MA +C + P +SG S NE + R ++ P+ ++ +G++ +
Sbjct: 511 VKAVEGMAEACEELGI----PVVSGNVSLYNETVEKNEIR-NVFPTPIVVGVGVLEKAEK 565
Query: 616 VPGSDFKKEGSAIYLVGKPQFSF---GGSVFAELFGIPSGESAAVPPFKKEAAELYKKLH 672
S +KE S +YLVG + + G + G+ G+ VPP E ++ L
Sbjct: 566 YTPSKVEKE-SELYLVGNLEENLRLDGSEYLKVIHGLIKGD---VPPVDLEKEKILINLL 621
Query: 673 SNIMKGLVLSC-HDLSEGGLAAALYEMCLS---GIGAELKEDFHTRLGASKIASLFGETT 728
+ +++C HD+S GGL AL EM G+ E+ D + F E
Sbjct: 622 ISFNNKELITCAHDVSVGGLLIALLEMVFRTPYGLEVEVYTDERPDV------FFFSENP 675
Query: 729 GCLLVEIK----EENRSAFEKEMEGASIYEIGKTCGKAGLKL 766
+++ ++ EE ++A EK G IGKT + +K+
Sbjct: 676 TRVIIGVESDKAEEVKNAVEK--AGLEWMYIGKTTEEKKIKV 715
>gi|110633630|ref|YP_673838.1| phosphoribosylformylglycinamidine synthase II [Mesorhizobium sp.
BNC1]
gi|110284614|gb|ABG62673.1| phosphoribosylformylglycinamidine synthase II [Mesorhizobium sp.
BNC1]
Length = 744
Score = 288 bits (737), Expect = 1e-75, Method: Composition-based stats.
Identities = 230/751 (30%), Positives = 348/751 (46%), Gaps = 95/751 (12%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ K + TS
Sbjct: 33 REPTFTELGIFSAMWNEHCSYKSSKRWLRTLPTS-------------------------- 66
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
P V+ +NAG+++ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 67 ----GPQVIQGPGENAGVVDIGDGQCVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTM 122
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG PD P + +++GV+ G+ YGN G+PTV G V++
Sbjct: 123 GARPIAAMNALRFGAPDHPKT---------QHLVAGVVAGIGGYGNSFGVPTVGGEVNFD 173
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV AG+A + G ++ LG KTGRDG+ GAT +S D T
Sbjct: 174 PRYNGNCLVNAFAAGLARTDGIFYSKAEGVGLPVVYLGAKTGRDGVGGATMASAEFD-ET 232
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ G AI D GA G + + EM + LG ++
Sbjct: 233 IEEKRPTVQVGDPFTEKCLLEACLELMATGAVIAIQDMGAAGLTCSAVEMGAKGDLGIEL 292
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL K+PV+ + ++ +E+ LSE+QERM++ + +K +++ ++ +GR T D
Sbjct: 293 DLDKVPVREERMSAYEMMLSESQERMLMVLRPEKEPEAEEIFRKWGLDFAIVGRTTDDLR 352
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHH 449
R+ G +E+ NL L P+ A PK P + D+ +L ++
Sbjct: 353 FRILHGGEEVANLPIKELGDEAPEYDRPWAEPK-MPPALDAATVPAADVADSLLKLLGSP 411
Query: 450 AVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQ 509
++S+ + YD +QG ++ P DA V++ +E KA+A S+ + PR
Sbjct: 412 DLSSRRWVWEQYDTLIQGNSLQIP--------GGDAGVVR-VEDHPTKALAFSSDVTPRY 462
Query: 510 GLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNT 569
D + A+ E RN A GADP A+ DN G+P RPE M + +
Sbjct: 463 CEADSFEGGKQAVAECWRNLTATGADP--LAVTDNLNFGNPERPEIMGQFVRAIKGIGEA 520
Query: 570 ALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIY 629
P +SG S NE L +IPP+ I+ +G++PD ++ F EG AI
Sbjct: 521 CRALSFPIVSGNVSLYNETLGQ-----AIPPTPTIAGVGLIPDWSKMARIAFAGEGQAIL 575
Query: 630 LVGKPQFSFGGSV--FAELFGIPSGESAAVPPF----KKEAAELYKKLHSNIMKGLVLSC 683
L G P+ S+G + A L + A PP +K + + + I G V +
Sbjct: 576 LAGAPE-SWGTHLGQSAYLRDVHGRAEGAPPPVDLAHEKRVGDFVRGV---IRSGTVTAA 631
Query: 684 HDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTG------------C 730
HD S+GGLA AL EM + SGIGA + + S A+ FGE G
Sbjct: 632 HDCSDGGLAVALAEMAMASGIGARIDAPVN-----SASAAFFGEDQGRYVLTAALAREDA 686
Query: 731 LLVEIKEENRSAFEKEMEGASIYEIGKTCGK 761
L + E+ R A G S+ IG T G+
Sbjct: 687 QLATLIEDARKA------GVSLIAIGVTGGR 711
>gi|114328334|ref|YP_745491.1| phosphoribosylformylglycinamidine synthase [Granulibacter
bethesdensis CGDNIH1]
gi|114316508|gb|ABI62568.1| phosphoribosylformylglycinamidine synthase [Granulibacter
bethesdensis CGDNIH1]
Length = 724
Score = 288 bits (736), Expect = 1e-75, Method: Composition-based stats.
Identities = 206/618 (33%), Positives = 309/618 (50%), Gaps = 52/618 (8%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
APWV+ +NAG+++ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 63 APWVIHGPGENAGVVDIGDGLAAIFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARP 122
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A + L FG PD PA KRII GV+ G+ YGN +G+PTV G V++H +Y
Sbjct: 123 VANLNALRFGSPDHPAT---------KRIIDGVVRGIGGYGNCVGVPTVGGEVNFHPSYN 173
Query: 218 SNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
NPLV GIAP+ + +A G+ +I +G KTGRDG+ GAT +S A + +
Sbjct: 174 GNPLVNAMTVGIAPKDRIFLSAAAGVGNPVIYVGSKTGRDGIHGATMASTEFGADSEE-K 232
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAK 333
+VQ+G+P +K + E ++ AI D GA G +S+ EMA +G ++DL
Sbjct: 233 RPTVQVGDPFTEKLLIEACLELMATDAIIAIQDMGAAGLTSSSVEMAGKGGVGIELDLDA 292
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P + +G+ +E+ LSE+QERM++ + D+ + + + + +++ +G T + V+
Sbjct: 293 VPQREEGMNAYEMMLSESQERMLMILRPDRQDVARAIFEKWELDFAVIGHLTDTGHIVVK 352
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYP------EYKEP-DLNAALKAVI 446
G + + P L P +P ++ P E +P + +AL +I
Sbjct: 353 HQ---------GVVEADIPLDPLAEQAPLYQRPTVETPKRAPLGEVADPVGIASALLTLI 403
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
+ S+ I YD V G TV RP DAAV++ TE +A+A++
Sbjct: 404 GSPDIASRRWIWDQYDSTVGGQTVRRPG-------AADAAVVRLDGTE--RALALTTDCT 454
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSC 566
PR DP A A+ E RN A GA P AI DN G+P +PE M R
Sbjct: 455 PRYCFADPEVGGAQAVAETWRNLTAVGAHP--LAITDNMNFGNPQKPEIMGQFAAAIRGM 512
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
L P +SG S NE +EG I P+ I +G++ + G + G
Sbjct: 513 REACLTLDFPVVSGNVSLYNE---TEG--TGILPTPAIGGLGVLDNAETATGLSLRP-GL 566
Query: 627 AIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK--LHSNIMKGLVLSCH 684
+ L+G + G S++ +G PP AAE + S I +G V +CH
Sbjct: 567 DLVLIGTGGTTLGQSLWLREI---AGREDGPPPAVDLAAERRHGDLVRSLIHQGKVAACH 623
Query: 685 DLSEGGLAAALYEMCLSG 702
DLS+GGL A+ EM ++G
Sbjct: 624 DLSDGGLLVAIAEMAIAG 641
>gi|126437494|ref|YP_001073185.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium sp.
JLS]
gi|126237294|gb|ABO00695.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium sp.
JLS]
Length = 768
Score = 287 bits (734), Expect = 2e-75, Method: Composition-based stats.
Identities = 241/768 (31%), Positives = 357/768 (46%), Gaps = 84/768 (10%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
R L E + IRE +RP TDAE + WSEHC +K+ K + G + TE+
Sbjct: 26 RELGLKDDEYQRIREILG--RRP-TDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTEKM 82
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
+ +L+ +NAG+++ + + V+FK E+HNHPS
Sbjct: 83 RST-------------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSY 117
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
+EP+ GA TGVGG++RD+M + ARP AV D L FG D P KR++ GV+
Sbjct: 118 VEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTKRVLDGVVR 168
Query: 193 GVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGG 250
GV YGN +G+P + G + +YA NPLV C G + H S AG+ II G
Sbjct: 169 GVGGYGNSLGLPNIGGETVFDPSYAGNPLVNALCVGAMRKEDLHLAFASGAGNKIILFGA 228
Query: 251 KTGRDGLRGATFSSMVMDASTGDVAGS------SVQIGEPIIQKKVAEVLIDARDQGLYS 304
+TG DG+ G S + D +GD +G+ SVQ+G+P ++K + E ++ L
Sbjct: 229 RTGLDGIGGV--SVLASDTFSGDESGAGRKKLPSVQVGDPFMEKVLIECCLELYAADLVV 286
Query: 305 AITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
I D G G S A E+ASA G V+L ++P++ + P E+ SE+QERM V D
Sbjct: 287 GIQDLGGAGLSCATSELASAGDGGMRVELDQVPLRAANMTPAEILSSESQERMCAVVTPD 346
Query: 363 KLEALQKLCDANDVELTNLGRFT-GDAVLRVRFGEKEIINLSCGFLHSGPP-QRKLKAAP 420
+EA +C +V T +G T GD ++ G+ + H GP QR +
Sbjct: 347 NVEAFLAVCRKWEVLATVIGEVTDGDRLVITWHGDTVVDVPPRTVAHEGPVYQRPVTRPD 406
Query: 421 PKDGKPFIKYPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDG 476
+D + P +L A L A+I + S+ I YD V+G TVL +
Sbjct: 407 TQDALNADTSADLPRPATGDELRATLLAMIGSPHLCSRGYITEQYDRYVRGNTVLAEH-- 464
Query: 477 PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADP 536
D V++ E G + +A+S + R LDPY A A+ EA RN GA P
Sbjct: 465 ------ADGGVLRIDEATG-RGIAVSTDASGRYTALDPYTGAQLALAEAYRNVAVTGATP 517
Query: 537 EKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRV 596
A+ + G P P MW + R + P G SF N+ S+
Sbjct: 518 --VAVTNCLNFGSPEDPGVMWQFSQAVRGLADGCAALGIPVTGGNVSFYNQTGST----- 570
Query: 597 SIPPSLLISAMGIVPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESA 655
+I P+ ++ +G++ D+ R+P + G + L+G + F GS++A+ + +G
Sbjct: 571 AILPTPVVGVLGVLDDVKRRIPTGLGTERGETLMLLGDTRDEFDGSIWAQ---VTAGHLG 627
Query: 656 AVPPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKED 710
+PP E L L + GL+ + HDLSEGGL A+ E L+G G + E+
Sbjct: 628 GLPPKVDLEREKLLADVLTAASRDGLISAAHDLSEGGLIQAVVEAALAGETGCRVLIPEN 687
Query: 711 FHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK--EMEGASIYEIG 756
F G LF E+ G +LV + S F E G I IG
Sbjct: 688 FEN--GTGPFTFLFSESAGRVLVAVPRTEESRFRAMCEARGLPITRIG 733
>gi|116669106|ref|YP_830039.1| phosphoribosylformylglycinamidine synthase II [Arthrobacter sp.
FB24]
gi|116609215|gb|ABK01939.1| phosphoribosylformylglycinamidine synthase II [Arthrobacter sp.
FB24]
Length = 772
Score = 287 bits (734), Expect = 2e-75, Method: Composition-based stats.
Identities = 229/748 (30%), Positives = 344/748 (45%), Gaps = 98/748 (13%)
Query: 27 EFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIK 86
E K R T AE + WSEHC +K+ K + G +T+E KK
Sbjct: 42 EVVKVLGRRPTGAELAMYSVMWSEHCSYKSSKNHLRQFGDKVTDEMKKD----------- 90
Query: 87 TYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGV 146
+L +NAG+ + + V+FK E+HN PS +EP+ GA TG+GG+
Sbjct: 91 --------------MLVGIGENAGVTNLGDGWAVTFKIESHNSPSFVEPYQGAATGIGGI 136
Query: 147 IRDVMGVSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGI 203
+RD++ + ARP AV D L FG HPDT R++ G + G+ YGN +G+
Sbjct: 137 VRDIISMGARPVAVMDPLRFGAIDHPDT------------ARVMHGAVAGIGGYGNSLGL 184
Query: 204 PTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGAT 261
P + G + + Y NPLV G+ R ++ G+ ++ G +TG DG+ GA+
Sbjct: 185 PNIGGEMVFDSVYQGNPLVNALAVGVMRHEDIRLANASGKGNKVVLFGARTGGDGIGGAS 244
Query: 262 FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEM 321
+ T +VQ+G+P +K + E ++ L I D GA G S A E+
Sbjct: 245 VLASESFDDTKPSKRPAVQVGDPFAEKVLIECCLELFKGSLVEGIQDLGAAGISCATSEL 304
Query: 322 ASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELT 379
AS G +V+L + ++ L P E+ +SE+QERM+ V + + A + + D VE +
Sbjct: 305 ASNGDGGMEVELTSVLLRDPTLTPGEILMSESQERMMAVVTPENVAAFEAVMDKWAVEYS 364
Query: 380 NLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP--- 436
LG T L + + + I+++ P+ P D +PF + PE+++
Sbjct: 365 WLGEVTDTGRLIITWEGEVIVDVD--------PRTVAHDGPVYD-RPFAR-PEWQDAVQA 414
Query: 437 -----------------DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEG 479
+L AA+ +I+ + K I YD V G T +
Sbjct: 415 DAFTGSVQDAGRPSAPKELAAAVTELISSPNMCDKSWITNQYDRYVGGNTAMA------- 467
Query: 480 NVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKT 539
P DA V++ E G VA++ N R LDPY A A+ EA RN +GA P
Sbjct: 468 -FPDDAGVVRVDEETG-LGVALATDANGRYTYLDPYHGAQLALAEAYRNVATSGAVP--M 523
Query: 540 AILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIP 599
A+ D G P P+ MW L E R + +V P G S N+ ++ I
Sbjct: 524 AVSDCLNFGSPEDPDVMWQLAEAIRGLSDACMVLGIPVTGGNVSLYNQTGTT-----PIH 578
Query: 600 PSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP 659
PS +++ +G + D+ R S +K++G AIYL+G GS +A + G G+ PP
Sbjct: 579 PSPVVAVLGKLDDVARRTPSGWKEDGQAIYLLGTTAAELDGSEWANMRGHLGGQ----PP 634
Query: 660 FKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELK-EDFHTRL 715
AAE L + L + G+V S HDLSEGGLAAAL E L G+GA + +D R
Sbjct: 635 KVDLAAERALGEILINASRDGMVDSAHDLSEGGLAAALVESALRYGVGARIALQDVMDRD 694
Query: 716 GASKIASLFGETTGCLLVEIKEENRSAF 743
G +LF ET G +V + F
Sbjct: 695 GVDLFTALFSETQGRAIVGVPRSEEVRF 722
Score = 67.4 bits (163), Expect = 3e-09, Method: Composition-based stats.
Identities = 71/290 (24%), Positives = 121/290 (41%), Gaps = 30/290 (10%)
Query: 104 SFVDNAGIIEFDEK--YEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVT 161
+F D+AG++ DE+ V+ + + + ++P+ GA + R+V A P AV+
Sbjct: 467 AFPDDAGVVRVDEETGLGVALATDANGRYTYLDPYHGAQLALAEAYRNVATSGAVPMAVS 526
Query: 162 DVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPL 221
D L FG P+ P ++ I G+ D +GIP G V + + P+
Sbjct: 527 DCLNFGSPEDP---------DVMWQLAEAIRGLSDACMVLGIPVTGGNVSLYNQTGTTPI 577
Query: 222 VYCGCAGIAPRGK----HRTKPSA----GDHIISLGGKTGRDGLRGATFSSMVMDASTGD 273
+A GK R PS G I LG L G+ +++M G
Sbjct: 578 HPSPV--VAVLGKLDDVARRTPSGWKEDGQAIYLLGTTAAE--LDGSEWANM-----RGH 628
Query: 274 VAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAK 333
+ G ++ + ++ + E+LI+A G+ + D GG ++A+ E A G +A
Sbjct: 629 LGGQPPKV-DLAAERALGEILINASRDGMVDSAHDLSEGGLAAALVESALRYGVGARIAL 687
Query: 334 IPV-KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
V G+ + SE Q R ++ VP + +C A T +G
Sbjct: 688 QDVMDRDGVDLFTALFSETQGRAIVGVPRSEEVRFTDMCTARGFAHTRIG 737
>gi|86610231|ref|YP_478993.1| phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
JA-2-3B'a(2-13)]
gi|110831830|sp|Q2JI39|PURL_SYNJB Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|86558773|gb|ABD03730.1| phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
JA-2-3B'a(2-13)]
Length = 768
Score = 286 bits (733), Expect = 3e-75, Method: Composition-based stats.
Identities = 224/686 (32%), Positives = 334/686 (48%), Gaps = 77/686 (11%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ E ++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP A+ + L F
Sbjct: 70 ENAGVVDLGEGDWLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTLGARPIALLNSLRF 129
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P T N +R+++ V+EG+ YGN +G+PTV G V Y+ NPLV
Sbjct: 130 G-PLTDPRN--------RRLMARVVEGIAHYGNCVGVPTVGGEVAVDPCYSGNPLVNVMA 180
Query: 227 AGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVM--DASTGDVAGSSVQIG 282
G+ P G+ ++ +G TGRDG+RGA+F+S + DA A VQ+G
Sbjct: 181 LGLLETPAVVKSAARGVGNPVLYVGATTGRDGIRGASFASAELKEDAQQDRPA---VQVG 237
Query: 283 EPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQG 340
+P + K + E ++A G A D GA G + + EMA+ +G DL ++P + G
Sbjct: 238 DPFLGKCLIEACLEAFATGAVVAAQDMGAAGITCSTAEMAAKGGVGIRFDLDRVPARESG 297
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+A WE LSE+QERM++ V + + ++ ++ + G + ++ + ++
Sbjct: 298 MAAWEYLLSESQERMLLVVQKGREAEVMEIFHRWGLQASVAGEVIAEPLVEIWHQGSCVV 357
Query: 401 NLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNA--------------ALKA 444
+ L P R + PP + ++ P + L
Sbjct: 358 QVPVRALAEDTPVYVRPVLPEPPAYVQAAWQWDPATLPPCDCQGIHLAQATLAWKEVLLQ 417
Query: 445 VINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK-----------PMET 493
++ + SK I R YDH+VQ TVL P G DAAVI+ P
Sbjct: 418 LLASPTLASKAWIYRQYDHQVQNNTVLWPGQG-------DAAVIRIRSQRFGVGEVPPLR 470
Query: 494 EGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRP 553
+KA+A + N R LDPY A +A+ EA RN GADP A+ DN G+P P
Sbjct: 471 ASRKAIAATLDGNGRWVYLDPYEGAKAAVAEAARNLTCVGADP--LAVTDNLNFGNPENP 528
Query: 554 ETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDI 613
W L R + TP G S NE L+ +G + +I P+ +I +G++PD+
Sbjct: 529 VVYWQLALACRGIGDACRALGTPVTGGNVSLYNETLTPQGSQ-AIYPTPVIGMVGLIPDL 587
Query: 614 GRVPGSDFKKEGSAIYLVGKPQF-SFGGSVF-AELFGIPSGESAAVPPFKKEAAELYKKL 671
+ G +++EG IYL+G S GGS + A + +G A V EL K++
Sbjct: 588 KCICGQGWQQEGDLIYLLGSQALTSLGGSEYLAVIHQQVTGRPAPVD------LELEKRV 641
Query: 672 HS----NIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKI---ASL 723
+ I +G V S HD SEGGLA AL E CLS G GA L L + +L
Sbjct: 642 QAACRHGIRQGWVRSAHDCSEGGLAVALAEACLSGGRGATLS------LAPGSLRWDQAL 695
Query: 724 FGETTGCLLVEIKEENRSAFEKEMEG 749
FGE + +LV + RSA+E +E
Sbjct: 696 FGEGSSRILVSVDPAQRSAWEAYLEA 721
>gi|118587336|ref|ZP_01544762.1| phosphoribosylformylglycinamidine synthase II [Oenococcus oeni ATCC
BAA-1163]
gi|118432160|gb|EAV38900.1| phosphoribosylformylglycinamidine synthase II [Oenococcus oeni ATCC
BAA-1163]
Length = 741
Score = 286 bits (733), Expect = 3e-75, Method: Composition-based stats.
Identities = 227/690 (32%), Positives = 340/690 (49%), Gaps = 66/690 (9%)
Query: 84 IIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGV 143
I+KT+ K + P + AGI++ + V FKAE+HNHPS +EP+ GA TGV
Sbjct: 66 ILKTFWSKNERVLQGPG------EGAGILDIGDGQAVVFKAESHNHPSQVEPYQGAATGV 119
Query: 144 GGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGI 203
GG++RD+ + A+P AV D L + K +I GVI+G+ YGN +GI
Sbjct: 120 GGILRDIFSMGAQPIAVLDSL---------RSSEIKNEQTKSLIDGVIDGIAGYGNAIGI 170
Query: 204 PTVNGGVHYHEAYASNPLVYCGCAGIA--PRGKHRTKPSAGDH-IISLGGKTGRDGLRGA 260
PTV G V + +AY N L G+ P + D+ +I +G KTGRDG+ GA
Sbjct: 171 PTVGGDVAFDDAYEGNLLCSVMSIGLVDHPHFIKVGQAHGKDNSVIYVGAKTGRDGINGA 230
Query: 261 TFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS--AITDCGAGGYSSAV 318
TF+S +S + S+VQ+G+P ++K V + I A + + AI D GA G S+
Sbjct: 231 TFASTEF-SSQEESQRSAVQVGDPFMEKLVMDATIKAVREMPEAVIAIQDMGAAGILSSS 289
Query: 319 GEMASALGCDV--DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDV 376
EM G + DL K+PV+ +G+ P+EL LSE+QERM++ V + + + L +
Sbjct: 290 SEMGEKGGSGIWLDLDKVPVREKGMIPYELMLSESQERMLLVVARGREKGVIDLYRDAGL 349
Query: 377 ELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQR-------KLKAAPPKDGKPFIK 429
+ +G+ T D+ R+ F + + +L L P + +K A + +P I
Sbjct: 350 DAVVIGKVTDDSRYRLSFQGETVADLDIKLLTKAPSYKLPSKLPVHIKKASQQQYQPKIS 409
Query: 430 YPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
P + +++ ++SK+ R +D V+ TV++P DAAVI+
Sbjct: 410 NPL-------QIIMQILSQPTISSKKFFYRHFDSIVRTDTVVKP--------GGDAAVIR 454
Query: 490 PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD 549
T KKA++++ +N R LDPY AI EA RN V+ GA P I D G+
Sbjct: 455 IRGT--KKALSLTTDVNGRYVYLDPYRGGQMAIAEAARNVVSTGALP--IGITDCLNFGN 510
Query: 550 PNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
P+ PE + L + N A TP +SG S N E +I P+ +I +G+
Sbjct: 511 PDNPEVYYELEQSVAGINNFAKQLNTPVVSGNVSLYN-----ETDNRAIYPTPMIGMVGL 565
Query: 610 VPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGE-SAAVPPFKKEAAELY 668
+ D ++ +FKK G IYL+G F GS E+ + +G+ S + F +A
Sbjct: 566 IRDNRKITTINFKKNGDLIYLIGSTGNDFNGS---EIQKLQTGKISGKLFDFDADAELNN 622
Query: 669 KKL-HSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGET 727
+KL + I GL+ S HDLSEGGL AL E S D + +L A LF ET
Sbjct: 623 QKLILTAIEAGLLKSAHDLSEGGLIVALLE---SAFETSFAFDANLKLDD---AQLFAET 676
Query: 728 TGCLLVEIKEENRSAFEKEMEGASIYEIGK 757
G +V ++ E FEK M G IG+
Sbjct: 677 NGRFIVTVEPEKEPVFEK-MAGDQAELIGR 705
>gi|116491150|ref|YP_810694.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Oenococcus oeni PSU-1]
gi|116091875|gb|ABJ57029.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Oenococcus oeni PSU-1]
Length = 741
Score = 286 bits (732), Expect = 4e-75, Method: Composition-based stats.
Identities = 226/692 (32%), Positives = 336/692 (48%), Gaps = 70/692 (10%)
Query: 84 IIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGV 143
I+KT+ K + P + AGI++ + V FKAE+HNHPS +EP+ GA TGV
Sbjct: 66 ILKTFWSKNERVLQGPG------EGAGILDIGDGQAVVFKAESHNHPSQVEPYQGAATGV 119
Query: 144 GGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGI 203
GG++RD+ + A+P AV D L F K +I GVI+G+ YGN +GI
Sbjct: 120 GGILRDIFSMGAQPIAVLDSLRFSEIKNE---------QTKSLIDGVIDGIAGYGNAIGI 170
Query: 204 PTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSAGDH-----IISLGGKTGRDGLR 258
PTV G V + +AY N L C I T H +I +G KTGRDG+
Sbjct: 171 PTVGGDVAFDDAYEGNLL--CNVMSIGLLDHQDTIKVGQAHGKDNSVIYVGAKTGRDGIN 228
Query: 259 GATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS--AITDCGAGGYSS 316
GATF+S +S + S+VQ+G+P ++K V + I A + + AI D GA G S
Sbjct: 229 GATFASTEF-SSQEESQRSAVQVGDPFMEKLVMDATIKAVREMPEAVIAIQDMGAAGILS 287
Query: 317 AVGEMASALGCDV--DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAN 374
+ EM G + DL K+PV+ +G+ P+EL LSE+QERM++ V + + + L
Sbjct: 288 SSSEMGEKGGSGIWLDLDKVPVREKGMIPYELMLSESQERMLLVVAQGREKGVIDLYRDA 347
Query: 375 DVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQR-------KLKAAPPKDGKPF 427
++ +G+ T D+ R+ F + + +L L P + +K A + +P
Sbjct: 348 GLDAVVIGKVTDDSRYRLSFQGETVADLDIKLLTKAPSYKLPSKLPVHIKKASQQQYQPK 407
Query: 428 IKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAV 487
I P + +++ ++SK+ R +D V+ TV++P DAAV
Sbjct: 408 ISNPL-------QIIMQILSQPTISSKKFFYRHFDSMVRTDTVVKP--------GGDAAV 452
Query: 488 IKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCL 547
I+ T KKA++++ +N R LDPY AI EA RN V+ G P I D
Sbjct: 453 IRIRGT--KKALSLTTDVNGRYVYLDPYRGGQMAIAEAARNVVSTGVLP--IGITDCLNF 508
Query: 548 GDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAM 607
G+P+ E + + N A TP +SG S N E +I P+ +I +
Sbjct: 509 GNPDNQEVYYESEQSVAGINNFAKQLNTPVVSGNVSLYN-----ETDNRAIYPTPMIGMV 563
Query: 608 GIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGE-SAAVPPFKKEAAE 666
G++ D ++ +FKK G IYL+G F GS E+ + +G+ S + F +A
Sbjct: 564 GLIRDNRKITTINFKKNGDLIYLIGSTGNDFNGS---EIQKLQTGKISGKLFDFDADAEL 620
Query: 667 LYKKL-HSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFG 725
+KL + I GL+ S HDLSEGGL AL E S D + +L A LF
Sbjct: 621 NNQKLILTAIEAGLLKSAHDLSEGGLIVALLE---SAFETSFAFDANLKLDD---AQLFA 674
Query: 726 ETTGCLLVEIKEENRSAFEKEMEGASIYEIGK 757
ET G +V +++E FEK M G IG+
Sbjct: 675 ETNGRFIVTVEQEKEPVFEK-MAGDQAELIGR 705
>gi|108801509|ref|YP_641706.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium sp.
MCS]
gi|119870662|ref|YP_940614.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium sp.
KMS]
gi|108771928|gb|ABG10650.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium sp.
MCS]
gi|119696751|gb|ABL93824.1| phosphoribosylformylglycinamidine synthase II [Mycobacterium sp.
KMS]
Length = 768
Score = 286 bits (732), Expect = 4e-75, Method: Composition-based stats.
Identities = 241/768 (31%), Positives = 357/768 (46%), Gaps = 84/768 (10%)
Query: 13 RRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQ 72
R L E + IRE +RP TDAE + WSEHC +K+ K + G + TE+
Sbjct: 26 RELGLKDDEYQRIREILG--RRP-TDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTEKM 82
Query: 73 KKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSA 132
+ +L+ +NAG+++ + + V+FK E+HNHPS
Sbjct: 83 RST-------------------------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSY 117
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
+EP+ GA TGVGG++RD+M + ARP AV D L FG D P KR++ GV+
Sbjct: 118 VEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAP---------DTKRVLDGVVR 168
Query: 193 GVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGG 250
GV YGN +G+P + G + +YA NPLV C G + H S AG+ II G
Sbjct: 169 GVGGYGNSLGLPNIGGETVFDPSYAGNPLVNALCVGAMRKEDLHLAFASGAGNKIILFGA 228
Query: 251 KTGRDGLRGATFSSMVMDASTGDVAGS------SVQIGEPIIQKKVAEVLIDARDQGLYS 304
+TG DG+ G S + D +GD +G+ SVQ+G+P ++K + E ++ L
Sbjct: 229 RTGLDGIGGV--SVLASDTFSGDESGAGRKKLPSVQVGDPFMEKVLIECCLELYAADLVV 286
Query: 305 AITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
I D G G S A E+ASA G V+L ++P++ + P E+ SE+QERM V D
Sbjct: 287 GIQDLGGAGLSCATSELASAGDGGMRVELDQVPLRAANMTPAEILSSESQERMCAVVTPD 346
Query: 363 KLEALQKLCDANDVELTNLGRFT-GDAVLRVRFGEKEIINLSCGFLHSGPP-QRKLKAAP 420
+EA +C +V T +G T GD ++ G+ + H GP QR +
Sbjct: 347 NVEAFLAVCRKWEVLATVIGEVTDGDRLVITWHGDTVVDVPPRTVAHEGPVYQRPVTRPD 406
Query: 421 PKDGKPFIKYPEYKEP----DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDG 476
+D + P +L A L A+I + S+ I YD V+G TVL +
Sbjct: 407 TQDALNADTSADLPRPATGDELRATLLAMIGSPHLCSRGYITEQYDRYVRGNTVLAEH-- 464
Query: 477 PEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADP 536
D V++ E G + +A+S + R LDPY A A+ EA RN GA P
Sbjct: 465 ------ADGGVLRIDEATG-RGIAVSTDASGRYTALDPYTGAQLALAEAYRNVAVTGATP 517
Query: 537 EKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRV 596
A+ + G P P MW + R + P G SF N+ S+
Sbjct: 518 --VAVTNCLNFGSPEDPGVMWQFSQAVRGLADGCAALGIPVTGGNVSFYNQTGST----- 570
Query: 597 SIPPSLLISAMGIVPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESA 655
+I P+ ++ +G++ D+ R+P + G + L+G + F GS++A+ + +G
Sbjct: 571 AILPTPVVGVLGVLDDVKRRIPTGLGTEPGETLMLLGDTRDEFDGSIWAQ---VTAGHLG 627
Query: 656 AVPPFKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKED 710
+PP E L L + GL+ + HDLSEGGL A+ E L+G G + E+
Sbjct: 628 GLPPKVDLEREKLLADVLTAASRDGLISAAHDLSEGGLIQAVVEAALAGETGCRVLIPEN 687
Query: 711 FHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK--EMEGASIYEIG 756
F G LF E+ G +LV + S F E G I IG
Sbjct: 688 FEN--GTGPFTFLFSESAGRVLVAVPRTEESRFRAMCEARGLPITRIG 733
>gi|84490248|ref|YP_448480.1| PurL [Methanosphaera stadtmanae DSM 3091]
gi|110831813|sp|Q2NEB6|PURL_METST Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|84373567|gb|ABC57837.1| PurL [Methanosphaera stadtmanae DSM 3091]
Length = 723
Score = 285 bits (730), Expect = 6e-75, Method: Composition-based stats.
Identities = 207/682 (30%), Positives = 340/682 (49%), Gaps = 61/682 (8%)
Query: 97 DAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSAR 156
D P V+ D+AGI+ ++Y ++ E+HNHPSA+EP+GGA TG+GG++RD++ + A+
Sbjct: 50 DGPDVILGPGDDAGIVSLTDEYALAIGMESHNHPSAVEPYGGAGTGIGGIVRDIISMGAK 109
Query: 157 PFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAY 216
P + D L FGH K I V++G+ DYGN++G+PTV G + + + +
Sbjct: 110 PVVLLDALRFGH---------MSNQRSKYIFDYVVKGISDYGNRIGVPTVGGEIEFDDNF 160
Query: 217 ASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
NP+V CAG+ + + + + P GD + +GG TGRDG+ G TF+S + +++
Sbjct: 161 QYNPMVNVVCAGLVKKDEIVYGSAPIVGDVYLLMGGTTGRDGIHGVTFASEELTSNSEVE 220
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLA 332
+VQ+ +P +K+V E + + + D G GG + + EMA G +DL
Sbjct: 221 DRPAVQVADPFTKKRVMEATYELLETLDIHGVKDLGGGGLTCCLSEMADKGGNGSLIDLN 280
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
KIP++ + + P+E+ LSE+QERMV A+ + +E ++C +D+ +G +
Sbjct: 281 KIPLREENMTPYEIMLSESQERMVFAIDSSDVEKAFEICKKHDLAHAIIGNIIDKREFII 340
Query: 393 RFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVN 452
+ E+EI + P + P K I+ E E D+ AL +++ +
Sbjct: 341 KDDEEEICHAPNILFTEAPIIEREAKEPEK----IIEDVEIPEVDVEEALYKLLSSENIT 396
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
SKE + YDHEVQ T+++P D DAAVIK + + + I N LL
Sbjct: 397 SKEWVYSQYDHEVQLRTIVKPGD--------DAAVIK---VDDETSFTIGTDCNSTHVLL 445
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALV 572
+PY AASA+ E++ NA++ GA P A++D G+P +PE W E + A
Sbjct: 446 NPYDGAASAVLESINNAISMGARP--IALVDCLNFGNPEKPEVFWQFKEAVSGMSDVAGK 503
Query: 573 FKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVG 632
F TPFISG SF NE +EG V++ PS ++ +G+V + ++ K +G I +VG
Sbjct: 504 FNTPFISGNVSFYNE---TEG--VTVNPSPIVGTVGVVENT-KIKTMTLKDDGDVILVVG 557
Query: 633 KPQFSFGGS-VFAELFGIPSGESAAVPP---------FKKEAAELYKKLHSNIMKGLVLS 682
GS + + + G PP +L K + NI S
Sbjct: 558 NTYPELDGSQYYKHIHNVVQG----YPPKIRLEENYNVSTTIEKLIPKYNDNIT-----S 608
Query: 683 CHDLSEGGLAAALYEMCL---SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
HD+S+GGL AL M + G+ + + + S+ L+ E+ ++ +KE+
Sbjct: 609 VHDISKGGLIIALALMSIKSKKGVNVNI-SNIPSTTELSQDDKLYSESNSRFIITVKEDA 667
Query: 740 RSAFEKEMEGASIYE--IGKTC 759
+ E+ + ++ IG C
Sbjct: 668 LTTIEEALSKNNVAYSVIGSVC 689
>gi|68548999|ref|ZP_00588467.1| Phosphoribosylformylglycinamidine synthase II [Pelodictyon
phaeoclathratiforme BU-1]
gi|68244130|gb|EAN26323.1| Phosphoribosylformylglycinamidine synthase II [Pelodictyon
phaeoclathratiforme BU-1]
Length = 760
Score = 285 bits (730), Expect = 7e-75, Method: Composition-based stats.
Identities = 197/604 (32%), Positives = 304/604 (50%), Gaps = 38/604 (6%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ + ARP A + L F
Sbjct: 76 ENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTMGARPVASLNSLRF 135
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P P H + ++ GV+ G+ DYGN G+PTV G +++ E Y NPLV
Sbjct: 136 GSPKDP---------HVRYLVDGVVRGIGDYGNSFGVPTVGGEIYFEEGYTGNPLVNAMS 186
Query: 227 AGIAPRGKHRTKPSAG--DHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
GI K + + G + ++ +G TGRDG+ GATF+S + ++ D SVQ+G+P
Sbjct: 187 VGIVEHHKTVSATALGKDNPVLIVGSSTGRDGIHGATFASEDLSEASED-KRPSVQVGDP 245
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-------ALGCDVDLAKIPVK 337
+K + E ++A G + D GA G +S+ EM++ + G ++DL +P++
Sbjct: 246 FAEKLLLEATLEAIATGYVVGLQDMGAAGITSSTSEMSARGIEKTGSGGIEIDLDLVPIR 305
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
G++ +E+ LSE+QERM+I E + ++ DV +GR T D +LRV
Sbjct: 306 EAGMSAYEIMLSESQERMLIVAEKGFEEKIIEVYRKWDVLAVVIGRVTSDNLLRVSQHGS 365
Query: 398 EIINLSCG--FLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
+ + L G P +A K P + E K D +++ + SK+
Sbjct: 366 IVAEIPAESLVLGGGAPVYIREAIEKKPETPIAQLEEDKNLDFPTIALELLSRPNIASKQ 425
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
+ R YD VQ TV P G+ DAAVI+ + +K +A+ N R L+P
Sbjct: 426 WVYRQYDSMVQTNTVT-----PVGHT--DAAVIRIKGS--RKGLAMKTDCNARYVYLNPL 476
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKT 575
A A+ E RN +GA P AI + G+P +PE + + F T
Sbjct: 477 AGGKIAVAECARNIACSGAKP--LAITNCLNFGNPYKPEVYFQFKTAVQGMGEACRAFNT 534
Query: 576 PFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQ 635
P G SF NE G R +I P+ I +G++ DI + GS F G AI L+G+P+
Sbjct: 535 PVTGGNVSFYNETFIG-GLRTAIYPTPTIGMIGLLDDIDNLVGSTFTNPGDAILLLGEPE 593
Query: 636 FSFGGSVFAEL-FGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAA 693
+ S + + +G P ++ ++ +K +L L S K L+ S HD+S+GGL
Sbjct: 594 LTLDASEYLIMQYGTPGQDAPSIDLVHEKNLQDLLVALAS---KKLLHSAHDISDGGLFV 650
Query: 694 ALYE 697
AL E
Sbjct: 651 ALAE 654
>gi|148556871|ref|YP_001264453.1| phosphoribosylformylglycinamidine synthase II [Sphingomonas
wittichii RW1]
gi|148502061|gb|ABQ70315.1| phosphoribosylformylglycinamidine synthase II [Sphingomonas
wittichii RW1]
Length = 724
Score = 285 bits (729), Expect = 8e-75, Method: Composition-based stats.
Identities = 219/688 (31%), Positives = 329/688 (47%), Gaps = 76/688 (11%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ ++I + T Q PG
Sbjct: 37 ELGIFSVMWSEHCSYKS--SRIHLKKLPTTGPQVICGPG--------------------- 73
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
+NAG+++ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 74 -------ENAGVVDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVA 126
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG PD P + +I+GV+ G+ YGN +G+PTV G V++H AY N
Sbjct: 127 NMNALRFGRPDHPKM---------RHLIAGVVHGIGGYGNCVGVPTVGGEVNFHAAYDGN 177
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A K + G+ I+ +G KTGRDG+ GAT +S + +
Sbjct: 178 ILVNAMTVGVAETNKIFYSAASGVGNPIVYVGSKTGRDGIHGATMASADFSEDSEE-KRP 236
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ + AI D GA G +S+ EMAS +G ++D+ +P
Sbjct: 237 TVQVGDPFTEKLLIEACLELMATDVIVAIQDMGAAGLTSSSVEMASKGGVGIELDMNAVP 296
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ G+ P+E+ LSE+QERM++ + + + + +++ +GR T + +RF
Sbjct: 297 CRETGMTPYEMMLSESQERMLMVLKPGREAEAEAIFRKWELDFAVIGRVTDTGRMVLRFD 356
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
+ + ++ G L P P +P + + L A++ + S+
Sbjct: 357 GETVCDIPLGPLADEAPLYDRPWVPTAPREPLGAVA--AKGSIGDNLVALMASPDLASRR 414
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
I YDH V TV RP DAAV++ T KK +AIS PR DP
Sbjct: 415 WIWEQYDHMVGADTVQRP--------GGDAAVVRVHGT--KKGIAISTDCTPRYVFADPV 464
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM----WALIEMARSCYNTAL 571
A AI E RN A GA P T NF G+P RPE M A+ MA++C AL
Sbjct: 465 EGGAQAIAECWRNITAVGAKPLATTDCMNF--GNPQRPEIMGQFVGAIEGMAKAC--AAL 520
Query: 572 VFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLV 631
F P +SG S NE + +G +I P+ I +G++ DI + FK I L+
Sbjct: 521 DF--PIVSGNVSLYNETKNDDGSGSAILPTPAIGGIGLLADIDAMATIAFKAADEHILLI 578
Query: 632 GKPQFSFGGSVFAELFGIPSGESAAVPP----FKKEAAELYKKLHSNIMKGLVLSCHDLS 687
G+ G S++ L + E PP +K + ++L I+ G V + HD+S
Sbjct: 579 GEDGAHLGQSLW--LRHVAGREDGPPPPVDLELEKRNGDFVREL---ILAGRVTAVHDVS 633
Query: 688 EGGLAAALYEMCLS-GIGAELKEDFHTR 714
+GGL AL EM L+ GIGA + + H R
Sbjct: 634 DGGLLVALAEMALAGGIGAHVDDLDHGR 661
>gi|50955787|ref|YP_063075.1| phosphoribosylformylglycinamidine synthase subunit II [Leifsonia
xyli subsp. xyli str. CTCB07]
gi|67460806|sp|Q6ACC3|PURL_LEIXX Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|50952269|gb|AAT89970.1| phosphoribosylformylglycinamide synthase [Leifsonia xyli subsp.
xyli str. CTCB07]
Length = 772
Score = 285 bits (728), Expect = 1e-74, Method: Composition-based stats.
Identities = 233/760 (30%), Positives = 346/760 (45%), Gaps = 74/760 (9%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E +IRE +RP T+ E + WSEHC +K+ K + G +T KK
Sbjct: 35 EYASIREILG--RRP-TNGELAMYSVMWSEHCSYKSSKIYLRQFGQKVTPAMKKN----- 86
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
++ +NAG+++ E + V+FK E+HNHPS IEPF GA
Sbjct: 87 --------------------LMVGMGENAGVVDIGEGWAVTFKVESHNHPSYIEPFQGAA 126
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD++ + ARP AV D L FG D P T H ++ GV+ G+ YGN
Sbjct: 127 TGVGGIVRDIISMGARPVAVMDQLRFGAIDEP------DTAH---VVHGVVSGISFYGNC 177
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK-HRTKPSA-GDHIISLGGKTGRDGLR 258
+G+P + G ++ Y NPLV G+ H S G+ ++ G +TG DG+
Sbjct: 178 LGLPNIGGETYFDPVYQGNPLVNALSVGVLRHEDLHLANASGVGNKVVLFGARTGGDGIG 237
Query: 259 GATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAV 318
GA+ + + G +VQ+G+P +K + E ++ L I D GA G S A
Sbjct: 238 GASILASDTFSEGGPTKRPAVQVGDPFAEKVLIECCLELYRDKLVEGIQDLGAAGISCAT 297
Query: 319 GEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDV 376
E+AS G ++L + ++ L E+ +SE+QERM+ V + L+ + DV
Sbjct: 298 SELASNGDGGMFIELDSVLLRDPSLTAEEILMSESQERMMAVVKPELLDQFLAVTAKWDV 357
Query: 377 ELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPK-------DGKPFIK 429
E + LG TG L + + +EI N+ + P + A P D +
Sbjct: 358 ETSVLGEVTGTGRLVINWHGEEIANVDPRTVAIDGPVYERPVAYPSWIDALRADSASALA 417
Query: 430 YPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
P + AL A++ + K I YD+ V G T L P DA +I+
Sbjct: 418 LPVSGDALREQAL-ALLGSANLADKSWITDQYDYFVGGNTALA--------FPDDAGMIR 468
Query: 490 PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGD 549
++ E AI+ N R LDP A A+ EA RN A+GA P A+ D G
Sbjct: 469 -VDEESGLGFAIATDANGRYCQLDPKEGAKLALAEAYRNVAASGAVP--AAVTDCLNFGS 525
Query: 550 PNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGI 609
P PE MW + + L P G SF N + V I P+ ++ +G+
Sbjct: 526 PENPEVMWQFSQAVEGLSDACLELGIPVTGGNVSFYN-----QTGDVPIFPTPVVGVLGV 580
Query: 610 VPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--L 667
+ D+ R + ++ EG IYL+G + GS +A G PP AAE L
Sbjct: 581 IDDVARRIPAGWQDEGENIYLLGITREELDGSAWA---ATVHGHLGGRPPAVDLAAERRL 637
Query: 668 YKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAEL-KEDFHTRLGASKIASLFG 725
+ LH+ +GL+ S HDL++GGLA AL E L G+GA + D R G ++LF
Sbjct: 638 AETLHAASQQGLISSAHDLADGGLAQALTESVLRFGVGARVWLGDIAERDGVDAASALFS 697
Query: 726 ETTGCLLVEIKEENRSAFEKEMEGASI--YEIGKTCGKAG 763
E+T +V + E+ F +G + IG T AG
Sbjct: 698 ESTARAIVSVPREDDVKFRGLCDGRGVPALRIGVTDAGAG 737
>gi|116495231|ref|YP_806965.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lactobacillus casei ATCC 334]
gi|116105381|gb|ABJ70523.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lactobacillus casei ATCC 334]
Length = 738
Score = 284 bits (727), Expect = 1e-74, Method: Composition-based stats.
Identities = 226/724 (31%), Positives = 346/724 (47%), Gaps = 92/724 (12%)
Query: 38 DAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDID 97
D E + WSEHC +K K +++ + K +
Sbjct: 40 DTEIGLASGMWSEHCAYKYSKP------------------------VLRQFWTKNERVLM 75
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
P + AG+I+ E V FKAE+HNHPSA+EP+ GA TGVGG+IRD+ + A+P
Sbjct: 76 GPG------EGAGVIDIGEGKAVVFKAESHNHPSAVEPYEGAATGVGGIIRDIFSIGAKP 129
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A+ D L FG + P H + ++ ++ G+ YGN +GIPTV G ++ +Y
Sbjct: 130 VAMLDSLAFGDIEQP---------HTQHLVDRIVAGIGGYGNAIGIPTVGGETNFDGSYT 180
Query: 218 SNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
NPLV C GI + + + +A G+ +I +G KTGRDG+ GA+F+S D S + A
Sbjct: 181 RNPLVNAMCVGIMDKDQIQKGKAAGVGNALIYVGAKTGRDGINGASFAS--GDFSDEEAA 238
Query: 276 G-SSVQIGEPIIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMASAL--GCDVD 330
S+VQ+G+P ++K + + ++ Q I D GA G S+ EMA G +D
Sbjct: 239 DRSAVQVGDPFMEKLLMDACLEITGHHQEALVGIQDMGAAGLVSSSVEMAGKANSGMVLD 298
Query: 331 LAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVL 390
L IP + + P+E+ LSE+QERM++ V + + + D++ +G
Sbjct: 299 LDLIPQRETEMTPFEIMLSESQERMLLCVRAGFEQEVLAVFADYDLDAAIVGHVIAGHQY 358
Query: 391 RVRFGEKEIINLSCGFLHSGPP----QRKLK---AAPPKDGKPFIKYPEYKEPDLNAALK 443
++ K + ++ L P Q K+ A P D P I P D+ A
Sbjct: 359 QLYHHGKLVCDVPVSSLTDDAPIYHQQGKMPKRLAQPAADFDPIITDPVQIWTDMMAM-- 416
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN 503
+ K + + YD +VQ TV+ P DAAV + T +A+A++
Sbjct: 417 -----PTIADKSSLYKRYDAQVQTNTVVLP--------GSDAAVTRIRGTH--RALAMTT 461
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
R LDP AA ++ EA RN VA+GA+P I D GDP +PE + L E A
Sbjct: 462 DSKGRYLYLDPQVGAAMSVAEAARNLVASGAEP--LGITDCLNFGDPTKPEAFYELAEAA 519
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
+ F P ISG S NE + G+ +I P+ +I +G++ D+ + + FK+
Sbjct: 520 KGIIAATKAFNAPVISGNVSLYNE---TNGE--AIYPTPMIGMVGLIEDLSTITTAAFKQ 574
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGE-SAAVPPFKKEAAELYKK-LHSNIMKGLVL 681
IYLVG+ F GS EL + +GE + + F EA + ++ + I + L+
Sbjct: 575 ADDLIYLVGETHGDFNGS---ELQKLQTGEVTGKLFDFDLEAEKQHQHFVLKAIREHLIT 631
Query: 682 SCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENR 740
+ HDLS+GGL AL EM +GA++ T G F ET G L+ + EN+
Sbjct: 632 AAHDLSDGGLLVALAEMGFDAQLGAQINVTLPTAWG-------FSETQGRFLLTVAPENQ 684
Query: 741 SAFE 744
+AFE
Sbjct: 685 AAFE 688
>gi|114704295|ref|ZP_01437203.1| phosphoribosylformylglycinamidine synthase subunit II [Fulvimarina
pelagi HTCC2506]
gi|114539080|gb|EAU42200.1| phosphoribosylformylglycinamidine synthase subunit II [Fulvimarina
pelagi HTCC2506]
Length = 740
Score = 284 bits (727), Expect = 2e-74, Method: Composition-based stats.
Identities = 227/738 (30%), Positives = 344/738 (46%), Gaps = 77/738 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ K ++T K
Sbjct: 31 RDPTITELGIFSAMWNEHCSYKSSK------------------------KWLRTLPTKGE 66
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
I P +NAG+++ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 67 RVIQGPG------ENAGVVDIGDGLCVVFKMESHNHPSFIEPYQGAATGVGGILRDVFTM 120
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P+ P + +++GV+ GV YGN G+PTV G V++H
Sbjct: 121 GARPIAAMNALRFGEPNHPKT---------RHLVAGVVAGVGGYGNSFGVPTVGGEVNFH 171
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV AG+A + G ++ LG KTGRDG+ GAT +S D T
Sbjct: 172 ARYNGNCLVNAFAAGLAKTDAIFYSKAEGIGLPVVYLGAKTGRDGVGGATMASAEFD-ET 230
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ G AI D GA G + + EM + LG ++
Sbjct: 231 IEEKRPTVQVGDPFTEKCLLEACLELMQTGAVIAIQDMGAAGLTCSAVEMGAKGDLGIEL 290
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL +PV+ ++P+E+ LSE+QERM++ + +K E + + D++ +G+ T D
Sbjct: 291 DLNAVPVRETSMSPYEMMLSESQERMLMVLRPEKREVAEAIFRKWDLDFAIVGKTTDDKR 350
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINH 448
R+ F KE+ +L L P+ PK + I + EP D A L ++
Sbjct: 351 FRIMFDGKEVADLPIKELGDEAPEYDRPWVEPKP-RAEISAGDIAEPADYGAVLLKLLGS 409
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
+ S+ + YD +QG T+ RP DA V++ ++ KA+A S+ + PR
Sbjct: 410 SDLCSRRWVYEQYDTLIQGNTLQRP--------GGDAGVVR-VDEHPTKALAFSSDVTPR 460
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
DPY A A+ E RN A GA P A DN G+P +PE M ++
Sbjct: 461 YCEADPYRGGAQAVAECWRNLTAVGATP--LAATDNLNFGNPEKPELMGVFVKAVEGIGA 518
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
P +SG S NE +I P+ I +G++ D + ++ +
Sbjct: 519 ACEALAFPIVSGNVSLYNETFGQ-----AILPTPTIGGVGLIEDRTKTAAIGAMEDDDVL 573
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA----AELYKKLHSNIMKGLVLSCH 684
+L+G G S++ L I E A PP +A + +KL I+ G+ +CH
Sbjct: 574 FLIGGDGSHLGASIY--LREIEGREEGAPPPVDFDAERRHGDFVRKL---IIGGIAKACH 628
Query: 685 DLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTG--CLLVEIKEENRSA 742
D+S+GGLA AL EMC+ ++ D G A LFGE + V+ KE R A
Sbjct: 629 DISDGGLAIALAEMCMQS-SRGMRIDAGQGFGH---ALLFGEDQARYVIAVKPKEVERIA 684
Query: 743 FEKEMEGASIYEIGKTCG 760
E E+ G + +G G
Sbjct: 685 KEAEIAGLPVRRLGVAGG 702
>gi|134103564|ref|YP_001109225.1| phosphoribosylformylglycinamidine synthase II [Saccharopolyspora
erythraea NRRL 2338]
gi|133916187|emb|CAM06300.1| phosphoribosylformylglycinamidine synthase II [Saccharopolyspora
erythraea NRRL 2338]
Length = 763
Score = 284 bits (727), Expect = 2e-74, Method: Composition-based stats.
Identities = 239/754 (31%), Positives = 353/754 (46%), Gaps = 86/754 (11%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E IRE +RP TDAE + WSEHC +K+ K + G + T E K
Sbjct: 33 EYARIREILG--RRP-TDAELAMYSVMWSEHCSYKSSKVHLKYFGETTTAEMKAK----- 84
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA
Sbjct: 85 --------------------MLAGIGENAGVVDIGDGWAVTFKLESHNHPSYVEPYQGAA 124
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+M + ARP AV D L FG D P KR++ GV+ GV YGN
Sbjct: 125 TGVGGIVRDIMAMGARPVAVADPLRFGPADAP---------DTKRVLPGVVAGVGGYGNC 175
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGI-APRGKHRTKPSA-GDHIISLGGKTGRDGLR 258
+G+P + G V + E+YASNPLV C G+ H S G+ II G +TG DG+
Sbjct: 176 LGLPNIGGEVVFDESYASNPLVNAMCVGVMKTEDLHLAHASGTGNKIILFGARTGLDGIG 235
Query: 259 GATFSSMVMDASTGDVAGS------SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAG 312
G S + + GD +G+ SVQ+G+P +K + E ++ GL I D G
Sbjct: 236 GV--SVLASETFEGDESGAGRKKLPSVQVGDPFAEKVLIECCLELYHSGLVVGIQDLGGA 293
Query: 313 GYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKL 370
G S A E+ASA G VDL ++P++ +G+ P E+ SE+QERM V ++A +
Sbjct: 294 GLSCATSELASAGDGGMRVDLDQVPLRAKGMNPAEILSSESQERMCAVVKPSDVDAFMDV 353
Query: 371 CDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPP-QRKLKAAPPKDGKPFI 428
C DV T +G T L + + ++ ++++ + H GP +R ++ +D
Sbjct: 354 CAKWDVTATVIGEVTEGENLEIYWHDELVVDVPPRTVAHQGPVYERPVERPAEQDLIAAD 413
Query: 429 KYPEYKEPDLNAALKAVINHHAVN----SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQD 484
P L+ + A + S+ + YD V+G TVL P D
Sbjct: 414 SAATLARPSTPDELRQTVLRMAASPNLCSRAWVTDQYDRYVRGNTVLAQ--------PSD 465
Query: 485 AAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDN 544
V++ ++ E + +A+S N R LDPYA A A+ EA RN GA P A+ +
Sbjct: 466 GGVLR-IDEETGRGIAVSTDCNARYTRLDPYAGAQLALAEAYRNVATTGATP--LAVTNC 522
Query: 545 FCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLI 604
G P P MW E R + P G SF N+ S I P+ ++
Sbjct: 523 LNFGSPEDPGVMWQFQEAVRGLADGCRELGIPVTGGNVSFYNQTGSK-----PILPTPVV 577
Query: 605 SAMGIVPDIG-RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKE 663
+G + D+ R+P ++G + L+G+ + FGGS +A++ G PP
Sbjct: 578 GVLGTIDDVTRRIPTGIGGEQGETLILLGETREEFGGSEWAKVVHDHLG---GTPPQVDL 634
Query: 664 AAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKEDFHTRLGAS 718
A E L + L + G++ + HDLSEGGLA AL E L G GA L ED A
Sbjct: 635 AREKLLAEVLVAGSRDGMISAAHDLSEGGLAQALVETALIGETGARVVLPED------AD 688
Query: 719 KIASLFGETTGCLLVEIKEENRSAFEKEMEGASI 752
LF E+ G +LV + F + S+
Sbjct: 689 PFVWLFSESAGRVLVAVPRSEELRFTEMCSARSL 722
Score = 67.0 bits (162), Expect = 4e-09, Method: Composition-based stats.
Identities = 68/286 (23%), Positives = 124/286 (43%), Gaps = 33/286 (11%)
Query: 108 NAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
+ G++ DE+ ++ + + + ++P+ GA + R+V A P AVT+ L
Sbjct: 465 DGGVLRIDEETGRGIAVSTDCNARYTRLDPYAGAQLALAEAYRNVATTGATPLAVTNCLN 524
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCG 225
FG P+ P G + + G+ D ++GIP G V ++ S P++
Sbjct: 525 FGSPEDP------GVMWQ---FQEAVRGLADGCRELGIPVTGGNVSFYNQTGSKPILPTP 575
Query: 226 CAGIAPRGKHRTK--PSA-----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
G+ T+ P+ G+ +I LG R+ G+ ++ +V D + G+
Sbjct: 576 VVGVLGTIDDVTRRIPTGIGGEQGETLILLG--ETREEFGGSEWAKVVHD----HLGGTP 629
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKIPV 336
Q+ + +K +AEVL+ G+ SA D GG + A+ E A G V L
Sbjct: 630 PQV-DLAREKLLAEVLVAGSRDGMISAAHDLSEGGLAQALVETALIGETGARVVLP---- 684
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
+ P+ SE+ R+++AVP + ++C A + +G
Sbjct: 685 --EDADPFVWLFSESAGRVLVAVPRSEELRFTEMCSARSLPWAKVG 728
>gi|150401881|ref|YP_001325647.1| phosphoribosylformylglycinamidine synthase II [Methanococcus
aeolicus Nankai-3]
gi|150014584|gb|ABR57035.1| phosphoribosylformylglycinamidine synthase II [Methanococcus
aeolicus Nankai-3]
Length = 732
Score = 284 bits (726), Expect = 2e-74, Method: Composition-based stats.
Identities = 217/748 (29%), Positives = 368/748 (49%), Gaps = 69/748 (9%)
Query: 17 LDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAY 76
+D+ +++ I E + ++P D E WSEHC +++ K + + G ++ E Q
Sbjct: 1 MDLNDLKFIEE--QLGRKP-NDVEIGMFENLWSEHCSYRSTKKLLSMFGKTVKENQNIVV 57
Query: 77 -PGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYE--VSFKAETHNHPSAI 133
PG D+A +I+ D++ + V+ E+HNHPS I
Sbjct: 58 GPG----------------------------DDAALIKIDDETDLCVAMAMESHNHPSYI 89
Query: 134 EPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEG 193
+P+ GA TGVGG++RD++ ++A+P A+ + L FG D E K + ++ GV++G
Sbjct: 90 DPYNGAATGVGGIVRDIISMNAKPIALLNALRFG--DINGEEKDK----VRWLVEGVVDG 143
Query: 194 VKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRT-KPSAGDHIISLGGKT 252
++DYGN++G+P V G + ++Y N LV C G+ G T K D + L G T
Sbjct: 144 IRDYGNRIGVPNVGGECEFDKSYDYNNLVNVVCIGLVKEGDIVTGKAKETDLTLILVGST 203
Query: 253 GRDGLRGATFSSM-VMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGA 311
GRDG+ GA+F+S + S GD SVQIG+ +K V + ++A AI D GA
Sbjct: 204 GRDGIGGASFASKDLTSESEGD--RPSVQIGDAFTEKCVIDSTLEACATKKVKAIKDLGA 261
Query: 312 GGYSSAVGEM--ASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQK 369
G +S+ E+ + +G ++ L + ++ +G+ +E+ +SE+QERM++AV E + K
Sbjct: 262 AGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMVSESQERMLLAVEKGSEEEIIK 321
Query: 370 LCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGP---PQRKLKAAPPKDGKP 426
+ + ++ ++ +G+ T V+ ++ +++L L + K D K
Sbjct: 322 IFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLCEATLTDSEEKETILETPDNKE 381
Query: 427 FIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAA 486
I PE E + + +NSK+ I YDHEVQ TV+RP +DA+
Sbjct: 382 NIAEPEPAELNNILLKLLKSPN--INSKKWIYEQYDHEVQLNTVVRP--------GKDAS 431
Query: 487 VIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFC 546
V++ E KA+A+ NP L+PY + + + E+VRN GA P +LDN
Sbjct: 432 VLRLKEAH-PKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKP--IGMLDNLN 488
Query: 547 LGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISA 606
G+P +PE + + + + A + P + G S NE + +GK I P+ +IS
Sbjct: 489 FGNPEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETV-IDGKDYPINPTPVISI 547
Query: 607 MGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEA-A 665
+G + +I +P KEG + + + GG+ + + I + E VP E
Sbjct: 548 VGTIENINNIPKG--AKEGDILIITAPTKDEMGGTEYYK--QIHNTEEGIVPKANLEVEK 603
Query: 666 ELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLF 724
E+Y K+ + GL+ D S+GGL A+ ++C++ IG EL + G LF
Sbjct: 604 EIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTNNIGVELDLGDYNTNGLRNDILLF 663
Query: 725 GETTGCLLVEIKEENRSAFEKEMEGASI 752
E++G +++ + + N KE+ GA I
Sbjct: 664 SESSGRIILSVDKNNADKVVKELNGAII 691
>gi|57640132|ref|YP_182610.1| phosphoribosylformylglycinamidine synthase subunit II [Thermococcus
kodakarensis KOD1]
gi|67460751|sp|Q5JFL7|PURL_PYRKO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|57158456|dbj|BAD84386.1| phosphoribosylformylglycinamidine synthase II [Thermococcus
kodakarensis KOD1]
Length = 713
Score = 284 bits (726), Expect = 2e-74, Method: Composition-based stats.
Identities = 194/602 (32%), Positives = 314/602 (52%), Gaps = 44/602 (7%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
++AGI++FD++ ++ E+HNHPSA+EP+GGA TGVGG++RD++ + ARP A+ D + F
Sbjct: 58 EDAGIVKFDDETWIAVGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRF 117
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P + ++ GV++G+ DYGN++G+PTV G + E+ + LV C
Sbjct: 118 G---------PLEKERNRYLLQGVVKGIADYGNRIGVPTVGGETEFDESLDNYTLVNVAC 168
Query: 227 AGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
GI H AG ++ +G +TGRDG+ G TF+S + + + S+VQI +P
Sbjct: 169 VGIMRPEHFVHSYVEEAGLKLVLVGNRTGRDGIHGVTFASEELSENAEEEDRSAVQIPDP 228
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKIPVKYQGLA 342
+K + E ++A G A+ D G GG + A EMA G + ++P++ +
Sbjct: 229 FTEKLLIEATLEAVYTGKVRALKDLGGGGLTCASSEMAGKKGFGAVIYADRVPLREPNMT 288
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
P E+ +SE+QERM+ AV + +E + K+ + +E T +G + V + +++ +L
Sbjct: 289 PTEVMISESQERMLFAVREEDVEEIGKIFEKYGLEWTVVGEIIKEPRYIVYWKGEKVADL 348
Query: 403 SCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDL--NAALKAVINHHAVNSKEDIVRL 460
L P + +P+ + + P + + A + V + V +K +
Sbjct: 349 PIDLLTEVP-------TIEWETRPYSLERDVETPKISFSDAFELVWSSPNVLNKRWVWEQ 401
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YDHEVQG TV++P +DAAV+K E G VA NP L+PY A
Sbjct: 402 YDHEVQGRTVVKP--------GRDAAVLKINERYGLAFVADG---NPNHSHLNPYHGAMG 450
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
A+ E VRN V+ GA+P A++DN P RPE W+ E R + A F ++SG
Sbjct: 451 AVAEVVRNLVSVGAEP--LALVDNLNFASPERPEVYWSFAETVRGLADAARAFGLAYVSG 508
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
SF NE + I P+ +++ +G V ++ ++PG +EG I +VG + GG
Sbjct: 509 NVSFYNEVVDR-----PIKPTPVVAGLGKV-ELEKIPGFGL-EEGLLIGVVGSTKRELGG 561
Query: 641 SVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL 700
S G+ G + V ++E A L + I +GL+ + HD+S+GG+A AL EM +
Sbjct: 562 SELYVRLGLKGGIAPRV-NLEEEKANAEGILEA-IRRGLLKAVHDVSKGGIAVALAEMAV 619
Query: 701 SG 702
G
Sbjct: 620 LG 621
>gi|51893993|ref|YP_076684.1| phosphoribosylformylglycinamidine synthetase [Symbiobacterium
thermophilum IAM 14863]
gi|67460800|sp|Q67KF8|PURL_SYMTH Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|51857682|dbj|BAD41840.1| phosphoribosylformylglycinamidine synthetase [Symbiobacterium
thermophilum IAM 14863]
Length = 778
Score = 283 bits (725), Expect = 3e-74, Method: Composition-based stats.
Identities = 227/747 (30%), Positives = 346/747 (46%), Gaps = 84/747 (11%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R + E E P E WSEHC +K KA + + P
Sbjct: 17 EYRRVVEILGREPNP---TELHMFGVMWSEHCAYKHSKAAL------------RRLP--- 58
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
VL +NAG++ D+ V+FK E+HNHPS ++PF GA
Sbjct: 59 ---------------TRGEHVLQGPGENAGVVRIDDDLAVAFKLESHNHPSFVDPFNGAA 103
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RDV + ARP A + L FG D P + + ++ GV+ G+ YGN
Sbjct: 104 TGVGGILRDVFTMGARPVATLNSLRFGPLDEPKQ---------RELLRGVVAGIGHYGNT 154
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGI-APRGKHR-TKPSAGDHIISLGGKTGRDGLR 258
+G+P + G V++ E+Y N LV C GI P HR G+ I+ +G TGRDG+
Sbjct: 155 VGVPCIGGEVYFDESYRGNCLVNAMCIGILRPDRIHRGIAAGPGNAIMVVGNPTGRDGIH 214
Query: 259 GAT-FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSA 317
A+ +S S + A +V +G+P +K + E ++ + I D GA G S+
Sbjct: 215 AASLLASAEFSGSEAEAALPTVPVGDPFAEKMLMEACLELFETDAVVGIQDMGAAGLISS 274
Query: 318 VGEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND 375
EMA+ +G ++D+ K+P + +G+ PWE LSE+QERM++ V + ++ +C
Sbjct: 275 SSEMAARGGVGVELDVRKVPAREEGMEPWEFLLSESQERMLVCVKKGREAEVEAICRKWG 334
Query: 376 VELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPP--KDGKPFIKYPEY 433
V +GR T D ++RV + + + L P KA P + + F +
Sbjct: 335 VGCAVIGRVTDDGMVRVLDDGRVVAEVPARALAEAPVYHPAKAEPAYLAELRAF-DWSRL 393
Query: 434 KEP-DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKP-- 490
EP D N L ++ + ++ I +DH VQ GTVL P G + V + A + P
Sbjct: 394 PEPEDWNETLLRLLGSPNIGARAWIYEQFDHMVQAGTVLGP--GGDAGVIRLGAAVAPGA 451
Query: 491 ----METEGK------------KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGA 534
+ G+ K +A S N R L+P A A+ EA RN V GA
Sbjct: 452 HGLTRQPPGEGLPGRSGQAGPPKGIAASVDCNGRYVYLNPRRGTAIAVAEAARNCVVTGA 511
Query: 535 DPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGK 594
P AI +N G+P +PE W E TP G SF NE + G+
Sbjct: 512 RP--VAITNNCNFGNPEKPEIFWTFDEAITGMAEACEALGTPVTGGNVSFYNE---TSGE 566
Query: 595 RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELF-GIPSGE 653
+I P+ I + + ++ R+ FK+ G I L+G+ + GGS +A L G+ +G+
Sbjct: 567 --AIHPTPTIGMIAVHENLDRLTTPGFKQVGDVILLLGETRDELGGSEYARLIHGVLAGD 624
Query: 654 SAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFH 712
+ A+ F+K ++ + I +GLV + HD++EGGLA AL EM ++ L
Sbjct: 625 APALDLAFEKRLQDVVLRA---IHEGLVTAAHDVAEGGLAVALAEMAIAAAEPSLGCQVS 681
Query: 713 TRLGASKI-ASLFGETTGCLLVEIKEE 738
LG ++ LFGE+ +LV E
Sbjct: 682 IFLGEGRVDGQLFGESQSRILVTATRE 708
>gi|73668082|ref|YP_304097.1| phosphoribosylformylglycinamidine synthase [Methanosarcina barkeri
str. Fusaro]
gi|110831812|sp|Q46F25|PURL_METBF Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|72395244|gb|AAZ69517.1| phosphoribosylformylglycinamidine synthase [Methanosarcina barkeri
str. Fusaro]
Length = 715
Score = 283 bits (725), Expect = 3e-74, Method: Composition-based stats.
Identities = 215/667 (32%), Positives = 322/667 (48%), Gaps = 63/667 (9%)
Query: 48 WSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVD 107
WSEHC +++ + P ++KT+ K + I P D
Sbjct: 30 WSEHCSYRS------------------SAP------LLKTFTSKGENVIIGPG------D 59
Query: 108 NAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFG 167
+A II+FD+ Y ++ E+HNHPS ++P+ GA TG+GG++RD++ + ARP A+ D L FG
Sbjct: 60 DAAIIKFDDGYVLAIGMESHNHPSYVDPYNGAATGIGGIVRDIISMGARPIALMDPLYFG 119
Query: 168 HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCA 227
DTP + +I+G+ YGN +G+P VNG + Y+ NPLV
Sbjct: 120 PLDTPKNMF---------LFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPLVNVVAV 170
Query: 228 GIAPRGKHRTKPS--AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPI 285
G+ + T S AG+ ++ G TG+DGL GA+F+S + S SVQ+G+P
Sbjct: 171 GLCREEEVITARSQKAGNKLVLAGSSTGKDGLGGASFASRDLSESAEAEDRPSVQVGDPY 230
Query: 286 IQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAP 343
+K V E+ ++A ++G + D GA G A E+A+ LG + + + +
Sbjct: 231 TEKLVIEMTLEAMEKGYIKSCKDLGAAGLGGASAELAAKGGLGAHITADAVTQREPNMNA 290
Query: 344 WELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLS 403
+E+ L+E+QERMV V + ++A+ L D+ +G T V F + ++++
Sbjct: 291 YEILLAESQERMVFEVAPEDVDAVLALVAKYDLNGAVVGYLTEKPNYTVEFKGEVVVDIP 350
Query: 404 CGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDH 463
FL G P + + P K P+ E DL AA VI+ + + SKE I R YDH
Sbjct: 351 IDFLTGGAPTCEKSSVAPIPQVEEGKAPKTPE-DLKAAFLKVISSYNIASKEWIYRQYDH 409
Query: 464 EVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAID 523
EVQ TV++P +DA V+K + KK + +S PR LLDPY + +
Sbjct: 410 EVQLRTVIKP--------GEDAGVLKITD---KKGLVLSCGCQPRATLLDPYNGGKNVVI 458
Query: 524 EAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDS 583
E N GAD AI++ G+P+RPE W L + A P + G S
Sbjct: 459 ENAMNLAVKGAD--GLAIVNCLNFGNPDRPEIYWQLKNSVLGLGDGARELSIPVVGGNVS 516
Query: 584 FNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVF 643
NE S+ + +I P+ I +G V +P S F K G AI LVG+ GGS +
Sbjct: 517 LYNE---SDEFKTAILPTPSIGIIGKVNFETPLPSSFFAKSGDAIILVGETTADMGGSEY 573
Query: 644 AELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SG 702
F + + VP K A E+ K + G + S HDLS GG+AA L MC SG
Sbjct: 574 YACF--EALNAGKVPSVPKNAPEIIKAVIEAARSGKLSSAHDLSLGGIAAGLARMCRNSG 631
Query: 703 IGAELKE 709
+L E
Sbjct: 632 AKVDLSE 638
>gi|91976230|ref|YP_568889.1| phosphoribosylformylglycinamidine synthase II [Rhodopseudomonas
palustris BisB5]
gi|91682686|gb|ABE38988.1| phosphoribosylformylglycinamidine synthase II [Rhodopseudomonas
palustris BisB5]
Length = 736
Score = 283 bits (724), Expect = 3e-74, Method: Composition-based stats.
Identities = 226/684 (33%), Positives = 335/684 (48%), Gaps = 66/684 (9%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
APWVL +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 66 APWVLQGPGENAGVIDIGDNQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARP 125
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A + L FG P+ P + ++SGV+ GV YGN G+PTV G +H Y
Sbjct: 126 IACLNALSFGAPEHPKT---------RHLVSGVVAGVGGYGNSFGVPTVGGQTRFHTRYD 176
Query: 218 SNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
N LV G+A K G I+ LG KTGRDG+ GAT +S + +
Sbjct: 177 GNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGMGGATMASAEFGEGSEE-K 235
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAK 333
+VQ+G+P +K + E ++ AI D GA G + + EM + LG D+DL
Sbjct: 236 RPTVQVGDPFAEKLLLEACLEIMANDCVIAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDA 295
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P + G+ +E+ LSE+QERM++ + +K + + + ++ +G T V+
Sbjct: 296 VPTRETGMTAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAVVGYTTPTKRFVVK 355
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYP--------EYKEPDLNA-ALKA 444
G K + +L P ++L P +P+++ P E P+ A AL+
Sbjct: 356 HGGKAMADL---------PIKELGDEAPLYDRPWVESPKLPVIHAREVNAPNSIADALEK 406
Query: 445 VINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNA 504
++ + SK + YDH + G T+ RP DAAV++ +G K +A++
Sbjct: 407 LLATPDLCSKRWVWEQYDHVIGGNTLQRP--------GGDAAVVRVQ--DGPKGLALTVD 456
Query: 505 LNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMAR 564
+ PR DP+ A+ EA RN A G P AI DN G+P RPE M + +
Sbjct: 457 VTPRYCEADPFEGGKQAVAEAWRNITAVGGKP--LAITDNLNFGNPERPEIMGQFVGCLK 514
Query: 565 SCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKE 624
+ F P +SG S NE + G+ + PS I +G++ D + FK E
Sbjct: 515 GIAEACIAFDFPVVSGNVSLYNE---TSGRGILPTPS--IGGVGLLDDFTKSATLAFKAE 569
Query: 625 GSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV---- 680
G AI L+G+ G SV+ L I E A PP +K H ++++G++
Sbjct: 570 GEAILLIGETHGWLGQSVY--LRDICGREEGAPPPVDLAC----EKRHGDVVRGMIHAGT 623
Query: 681 -LSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEE 738
+ HDLS+GGL AL EM L+G IGA L+ G A FGE G LV +KE+
Sbjct: 624 ATAVHDLSDGGLLVALAEMALAGSIGASLEAPPD---GIVPHAWWFGEDQGRYLVTVKED 680
Query: 739 NRSAFEKEME--GASIYEIGKTCG 760
+ +M+ G S +IG+T G
Sbjct: 681 DLLTVLSKMKSVGVSCEQIGRTAG 704
>gi|118616264|ref|YP_904596.1| phosphoribosylformylglycinamidine synthase II, PurL [Mycobacterium
ulcerans Agy99]
gi|118568374|gb|ABL03125.1| phosphoribosylformylglycinamidine synthase II, PurL [Mycobacterium
ulcerans Agy99]
Length = 765
Score = 283 bits (723), Expect = 4e-74, Method: Composition-based stats.
Identities = 227/735 (30%), Positives = 356/735 (48%), Gaps = 91/735 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP TD E + WSEHC +K+ K + G + T+E +
Sbjct: 44 RRP-TDTELAMYSVMWSEHCSYKSSKVHLRYFGETTTDEMRAG----------------- 85
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA TGVGG++RD+M
Sbjct: 86 --------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMA 137
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP AV D L FG D P +R++ GV+ GV YGN +G+P + G +
Sbjct: 138 MGARPIAVVDQLRFGAADAP---------DTRRVLDGVVRGVGGYGNSLGLPNIGGDTVF 188
Query: 213 HEAYASNPLVYCGCAGIAPRGK-HRTKPS-AGDHIISLGGKTGRDGLRGATFSSMVMDAS 270
YA NPLV C G+ + H S AG+ II G +TG DG+ G + + +S
Sbjct: 189 DACYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFSS 248
Query: 271 TGDVAGS-----SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA- 324
G+ G+ SVQ+G+P ++K + E ++ GL I D G G S A E+ASA
Sbjct: 249 DGEGEGARKKLPSVQVGDPFMEKVLIECCLELYSGGLVIGIQDLGGAGLSCATSELASAG 308
Query: 325 -LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGR 383
G ++L +P++ + + P E+ SE+QERM V + ++A +C DV T +G
Sbjct: 309 DGGMAINLEAVPLRAKEMTPAEVLCSESQERMCAVVSPENVDAFMAVCRKWDVLATVIGE 368
Query: 384 FTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAPPK------DGKPFIKYPEYKEP 436
T LR+ + + ++++ + H GP ++ A P D + P +
Sbjct: 369 VTEGDRLRITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADSSKSLPRPATGD- 427
Query: 437 DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGK 496
+L A L A++ + S+ I YD V+G TVL + + V++ E G
Sbjct: 428 ELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEH--------ANGGVLRIDEATG- 478
Query: 497 KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM 556
+ +A+S + R LLDPY A A+ EA RN A GA P A+ + G P P M
Sbjct: 479 RGIALSTDASGRYTLLDPYTGAQLALAEAYRNVAATGATP--VAVTNCLNFGSPEDPGVM 536
Query: 557 WALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIG-R 615
W + R + + P G SF N+ S+ +I P+ ++ +G++ D+ R
Sbjct: 537 WQFAQAVRGLADGCVALGIPVTGGNVSFYNQTGST-----AIMPTPVVGVLGVIDDVTRR 591
Query: 616 VPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNI 675
+P + + + L+G + GS++A++ G G PP A E KL +++
Sbjct: 592 IPTAMGAEPSETLMLLGDTRDELDGSIWAQVTGEHLG---GTPPAVDLARE---KLLADV 645
Query: 676 MK-----GLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKEDFHTRLGASKIASLFGET 727
++ GLV + HDLSEGGLA A+ E L+G G L +D A LF E+
Sbjct: 646 LRAASRDGLVSAAHDLSEGGLAQAIVESALAGETGCRIVLPDD------ADPFVMLFSES 699
Query: 728 TGCLLVEI--KEENR 740
G +LV + EE+R
Sbjct: 700 AGRVLVAVPRTEESR 714
Score = 75.1 bits (183), Expect = 2e-11, Method: Composition-based stats.
Identities = 72/285 (25%), Positives = 121/285 (42%), Gaps = 31/285 (10%)
Query: 108 NAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
N G++ DE ++ + + ++P+ GA + R+V A P AVT+ L
Sbjct: 467 NGGVLRIDEATGRGIALSTDASGRYTLLDPYTGAQLALAEAYRNVAATGATPVAVTNCLN 526
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN---PLV 222
FG P+ P G + + + G+ D +GIP G V ++ S P
Sbjct: 527 FGSPEDP------GVMWQ---FAQAVRGLADGCVALGIPVTGGNVSFYNQTGSTAIMPTP 577
Query: 223 YCGCAGIAPRGKHRTKPSAG---DHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSV 279
G G+ R + G + L G T RD L G+ ++ + TG+ G +
Sbjct: 578 VVGVLGVIDDVTRRIPTAMGAEPSETLMLLGDT-RDELDGSIWAQV-----TGEHLGGTP 631
Query: 280 QIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGE--MASALGCDVDLAKIPVK 337
+ +K +A+VL A GL SA D GG + A+ E +A GC + L
Sbjct: 632 PAVDLAREKLLADVLRAASRDGLVSAAHDLSEGGLAQAIVESALAGETGCRIVLP----- 686
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
P+ + SE+ R+++AVP + L+ +C+A + +G
Sbjct: 687 -DDADPFVMLFSESAGRVLVAVPRTEESRLRAMCEARRLPAVRIG 730
>gi|87200270|ref|YP_497527.1| phosphoribosylformylglycinamidine synthase II [Novosphingobium
aromaticivorans DSM 12444]
gi|110831817|sp|Q2G630|PURL_NOVAD Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|87135951|gb|ABD26693.1| phosphoribosylformylglycinamidine synthase II [Novosphingobium
aromaticivorans DSM 12444]
Length = 719
Score = 283 bits (723), Expect = 4e-74, Method: Composition-based stats.
Identities = 227/744 (30%), Positives = 345/744 (46%), Gaps = 92/744 (12%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + + TS AP
Sbjct: 34 ELGIFSVMWSEHCSYKSSRIHLKKLPTS------------------------------AP 63
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 64 WVICGPGENAGVIDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVA 123
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG PD P K ++ GV+ G+ YGN +G+PTV G ++H+AY N
Sbjct: 124 NMNALRFGRPDHPKM---------KHLVQGVVAGIGGYGNCVGVPTVGGETNFHKAYDGN 174
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A K + G+ I+ +G KTGRDG+ GAT +S D + D
Sbjct: 175 ILVNAMTVGVADTDKIFYSAATGLGNPIVYVGSKTGRDGIHGATMASADFDEKS-DEKRP 233
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ AI D GA G +S+ EMA+ G +D+ K+P
Sbjct: 234 TVQVGDPFTEKLLIEACLELMATDAIVAIQDMGAAGLTSSSVEMATNGKAGIILDMDKVP 293
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ +G+ P+E+ LSE+QERM++ + K + + +++ +G T + ++F
Sbjct: 294 CREEGMTPYEMMLSESQERMLMVLKPGKEAMAEAIFRKWELDFAVIGEVTDTGHMVLKFQ 353
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGK------PFIKYPEYKEPDLNAALKAVINHH 449
+ + ++ G L P A D K P PE DL A L +I
Sbjct: 354 GETVCDIPLGPLAEDAPLYDRPALSLADYKAWANVAPLGTVPE--STDLGADLVKLIGCP 411
Query: 450 AVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQ 509
+ ++ I YD +V G L+ G DAAV++ T KA+AIS PR
Sbjct: 412 DLANRRWIFEQYDSQV-GADTLQKSGG-------DAAVVRIHGTS--KALAISTDCTPRY 461
Query: 510 GLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNT 569
DPY A+ E RN A GA P AI + +P RPE M +++ +
Sbjct: 462 CYADPYEGGKQAVAETWRNICAVGARP--LAITNCLNFANPQRPEIMAQIVQALNGMGDA 519
Query: 570 ALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIY 629
P +SG S NE ++ G +I P+ I +G++ D + FK EG AI+
Sbjct: 520 CRALDYPIVSGNVSLYNESKATGGGS-AILPTPAIGGVGLMLDHEVMTTVAFKDEGDAIW 578
Query: 630 LVGKPQFSFGGSVF-AELFGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLS 687
LVG G S++ E+ G G++ +V ++ E ++ I G + + HD+S
Sbjct: 579 LVGGEGTHLGQSLYLREIHGREDGDAPSVDLAVERRNGE---QVREWIAAGRLSAVHDIS 635
Query: 688 EGGLAAALYEMCLSG-----------IGAELKED-----FHTRL-----GASKIASLFG- 725
+GGL AL EM L+G A ED TR GA+++ ++ G
Sbjct: 636 DGGLLVALTEMALAGNKGCTLDIALTTAAAFGEDQSRYVVTTRAGEVLEGATRLGTVGGS 695
Query: 726 ETTGCLLVEIKEENRSAFEKEMEG 749
+ G L ++E N + F MEG
Sbjct: 696 QVAGVELAALREANEAFFRDWMEG 719
>gi|31789477|gb|AAP58590.1| putative phosphoribosylformylglycinamidine synthase II [uncultured
Acidobacteria bacterium]
Length = 746
Score = 283 bits (723), Expect = 5e-74, Method: Composition-based stats.
Identities = 219/747 (29%), Positives = 343/747 (45%), Gaps = 98/747 (13%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + + T+ P
Sbjct: 33 ELGIFSVMWSEHCSYKSSRVHLRTLPTT------------------------------GP 62
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
VL +NAG ++ E FK E+HNHPS IEP+ GA TGVGG+IRD+ + ARP A
Sbjct: 63 RVLQGPGENAGAVDIGEGLAAVFKIESHNHPSFIEPYQGAATGVGGIIRDIFTMGARPIA 122
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ D L FG D PA +R ++GV+ G+ YGN +GIPTV G + + E+Y N
Sbjct: 123 LLDSLRFGSLDDPA---------VRRTMAGVVAGIGGYGNSIGIPTVGGEIGFDESYTGN 173
Query: 220 PLVYCGCAGIAPRGKHRTKPS--AGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
PLV C GIA + T + AG+ + +G KTGRDG+ GAT +S D ++ +
Sbjct: 174 PLVNVFCLGIARTDEIITASASGAGNPVYYVGAKTGRDGIHGATMASAEFDETSAE-KRP 232
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P ++K + E ++ I D GA G + + EM S G ++D++ +P
Sbjct: 233 AVQVGDPFMEKLLLEACLEVMKTDALVGIQDMGAAGLTCSTCEMGSRGGAGVEIDVSLVP 292
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ G+ P+E+ LSE+QERM++ + ++++ + D+ +G T D +RV+
Sbjct: 293 QRETGMTPYEIMLSESQERMLLVAKKGREAEVERIFEKWDLHAVPIGVVTTDGKMRVK-- 350
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKE------------PDLNAALK 443
G + + P L P +P + KE P+ +
Sbjct: 351 -------ERGIVVAEIPNAALTDEAPVYHRPMTEPAYLKEAQRLDITALGPAPEPSEVFT 403
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN 503
++ + SK + YDH V+ T++ P G A V++ T +A+A+S
Sbjct: 404 RLLASPGIASKRWVYTQYDHMVRTNTLVLPGMG--------AGVVRVKGTS--RALALST 453
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
N R LDP+A A A+ EA RN AGA+P NF G+P RPE MW +
Sbjct: 454 DCNGRFVYLDPFAGAQLAVAEASRNVACAGAEPIGATNCLNF--GNPERPEIMWQFAKAV 511
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
P G S NE ++G+ ++ P+ ++ +G++ FK
Sbjct: 512 EGMGAACRALGIPITGGNVSLYNE---TDGR--AVLPTPVLGVVGLLERAETAVTRAFKA 566
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP---FKKEAAELYKKLHSNIMKGLV 680
+G + ++G+ GGS E G +PP +EAA L + L +GL+
Sbjct: 567 DGDVVVVLGESFAELGGS---EYLKAVHGLIRGMPPSLDLAREAA-LQRLLVKGATQGLI 622
Query: 681 LSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGAS----KIASLFGETTGCLLVEI 735
S HD +EGGLA L E C +G+G ++ D GA+ + +LFGE+ ++V +
Sbjct: 623 RSAHDCAEGGLAVTLAECCFDTGMGVDI--DLGAVTGAAPGLDAVTALFGESASRVVVSV 680
Query: 736 KEENRSAF--EKEMEGASIYEIGKTCG 760
SA EG +G+ G
Sbjct: 681 TRAQESALLALASAEGVPAQPVGRVEG 707
Score = 65.1 bits (157), Expect = 2e-08, Method: Composition-based stats.
Identities = 64/265 (24%), Positives = 103/265 (38%), Gaps = 24/265 (9%)
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
++PF GA V R+V A P T+ L FG+P+ P + +E
Sbjct: 462 LDPFAGAQLAVAEASRNVACAGAEPIGATNCLNFGNPERP---------EIMWQFAKAVE 512
Query: 193 GVKDYGNKMGIPTVNGGVHYH---EAYASNPLVYCGCAGIAPRGKH---RTKPSAGDHII 246
G+ +GIP G V + + A P G G+ R + R + GD ++
Sbjct: 513 GMGAACRALGIPITGGNVSLYNETDGRAVLPTPVLGVVGLLERAETAVTRAFKADGDVVV 572
Query: 247 SLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAI 306
LG G S + A G + G + + + + +L+ QGL +
Sbjct: 573 VLGESFAELG------GSEYLKAVHGLIRGMPPSL-DLAREAALQRLLVKGATQGLIRSA 625
Query: 307 TDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL 364
DC GG + + E + +G D+DL + GL E+ R+V++V +
Sbjct: 626 HDCAEGGLAVTLAECCFDTGMGVDIDLGAVTGAAPGLDAVTALFGESASRVVVSVTRAQE 685
Query: 365 EALQKLCDANDVELTNLGRFTGDAV 389
AL L A V +GR G +
Sbjct: 686 SALLALASAEGVPAQPVGRVEGSRI 710
>gi|86743092|ref|YP_483492.1| phosphoribosylformylglycinamidine synthase II [Frankia sp. CcI3]
gi|108936019|sp|Q2J4M9|PURL_FRASC Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|86569954|gb|ABD13763.1| phosphoribosylformylglycinamidine synthase II [Frankia sp. CcI3]
Length = 761
Score = 283 bits (723), Expect = 5e-74, Method: Composition-based stats.
Identities = 231/753 (30%), Positives = 350/753 (46%), Gaps = 96/753 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKI-DIDGTSLTEEQKKAYPGLCVNSIIKTYIKK 91
+RP +DAE + WSEHC +K+ K + T LT+
Sbjct: 40 RRP-SDAELAMYSVMWSEHCSYKSSKVHLRQFRDTPLTDR-------------------- 78
Query: 92 ATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVM 151
+L +NAG+++ E V+FK E+HNHPS +EP+ GA TGVGG++RD++
Sbjct: 79 ---------LLVGMGENAGVVDVGEGLAVTFKIESHNHPSFVEPYQGAATGVGGIVRDIL 129
Query: 152 GVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVH 211
+ ARP V D L FG D R++ GV+ G+ YGN +G+PT+ G V
Sbjct: 130 TMGARPIGVLDPLRFGEADAA---------DTARVLPGVVAGIGGYGNCLGLPTIGGEVV 180
Query: 212 YHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGAT-FSSMVMD 268
+ YA NPLV C G+ P + +T + G+ ++ LG KTGRDG+ G + +S D
Sbjct: 181 FDPTYAGNPLVNALCVGVMPVDRVQTSAATGVGNAVVLLGAKTGRDGIGGVSILASATFD 240
Query: 269 ASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA---- 324
G SVQ+G+P +K + E ++ D+ L + I D G G + A+ E +A
Sbjct: 241 EGGGPARRPSVQVGDPFTEKILIETCLELFDRKLVTGIQDLGGAGLTCALTETTAAGIAT 300
Query: 325 ---LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
G +VDL +P++ +A E+ SE+QERM+ V + L + L + V T +
Sbjct: 301 GQPGGMEVDLDLVPLREASMAAHEVLASESQERMLAIVTPEALPEVLALAERWGVLATRI 360
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFL-HSGP----PQRK------LKAAPPKDGKPFIKY 430
G T L VR+ + ++++ G L GP P R+ ++A P + +
Sbjct: 361 GTVTNSGRLTVRWHGEVVVDVPPGSLADDGPVYERPLRRPVDFDLVRADAPTPAR--LAR 418
Query: 431 PEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKP 490
P P+L L ++ + S+ + YD VQ GTVL P+DA V++
Sbjct: 419 PR-TGPELRETLLRLVASPNLCSRAWVTDQYDRYVQAGTVLAQ--------PEDAGVLRL 469
Query: 491 METEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP 550
G +A++ N R LDP+A A+ EA RN AAG+ P A+ + G P
Sbjct: 470 SAATG-LGIALATDGNGRYARLDPFAGTQLALAEACRNVAAAGSVP--IAVTNCLNFGSP 526
Query: 551 NRPETMWALIE----MARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISA 606
PE MW + +A C L P G SF N+ S+ I P+ +I
Sbjct: 527 EDPEVMWQFAQACAGLAEGCRRLGL----PVTGGNVSFYNQTGST-----PIHPTPVIGV 577
Query: 607 MGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE 666
+G+ D+ R F +EG + L+G+ FGGS +A + G F +E
Sbjct: 578 LGLFDDVTRRTPIGFAEEGDVLILLGETADEFGGSEWAWVTHRHLGGEPPAVDFAREKL- 636
Query: 667 LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFG 725
L + L + G++ + HDLS+GGLA AL E CL G GA + G+ LF
Sbjct: 637 LGEILVAGSRDGMLTAAHDLSDGGLAQALVESCLRGGHGARII----LPAGSDPFVELFS 692
Query: 726 ETTGCLLVEI--KEENRSAFEKEMEGASIYEIG 756
E+ G +V + EE R E+ G +G
Sbjct: 693 ESAGRAVVAVPRAEELRFTDMCEVRGLPWRRVG 725
>gi|121601697|ref|YP_989150.1| phosphoribosylformylglycinamidine synthase II [Bartonella
bacilliformis KC583]
gi|120613874|gb|ABM44475.1| phosphoribosylformylglycinamidine synthase II [Bartonella
bacilliformis KC583]
Length = 737
Score = 282 bits (721), Expect = 6e-74, Method: Composition-based stats.
Identities = 228/743 (30%), Positives = 351/743 (47%), Gaps = 82/743 (11%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ K +KT K
Sbjct: 33 REPTFTELGIFSAMWNEHCSYKSSK------------------------KWLKTLPTKGK 68
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
I P +NAG+++ V FK E+HNHPS IEP+ GA TG+GG++RD+ +
Sbjct: 69 CVIQGPG------ENAGVVDIGNGQCVVFKMESHNHPSYIEPYQGAATGIGGILRDIFTM 122
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG PD P + ++SGV+ G+ Y N G+PTV G V++
Sbjct: 123 GARPVAAINALRFGSPDHP---------RTRHLVSGVVSGIGGYSNAFGVPTVGGEVNFD 173
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
+ Y N LV AGIA + G ++ LG KTGRDG+ GAT +S D +
Sbjct: 174 KRYNGNILVNAFAAGIAKIDSIFYSKAQGVGLPVVYLGAKTGRDGVGGATMASAEFDDAI 233
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
D +VQ+G+P +K + E ++ AI D GA G +S+ EM + LG ++
Sbjct: 234 -DEKRPTVQVGDPFTEKCLLEACLELMALKAVIAIQDMGAAGLTSSSVEMGAKGNLGIEL 292
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L KIPV+ + + +E+ LSE+QERM++ + + + + ++ + +G+ T D
Sbjct: 293 NLDKIPVREENMTAYEIMLSESQERMLMVLKPEMEKQAAAIFHKWGLDFSIIGKTTDDLR 352
Query: 390 LRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKE-PDLNAALKAVI 446
RV KE++NL L P R A P K +K E KE + AL ++
Sbjct: 353 FRVLHQGKEVVNLPIKELGDEAPVYDRPWIAPSP---KAILKAEEVKEIENFGDALLTLL 409
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALN 506
N +S+ + YD +QG +++RP DA VI+ ++ K A+A S+ +
Sbjct: 410 NSADQSSRRWVYEQYDTFIQGNSLVRP--------GGDAGVIR-VDNNDKHALAFSSDVT 460
Query: 507 PRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSC 566
PR DPY A+ E RN A GA P A DN G+P +PE M L+ +
Sbjct: 461 PRYCEADPYEGGKQAVAECWRNISATGATP--LAATDNLNFGNPEKPEIMGQLVFAIKGI 518
Query: 567 YNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGS 626
P +SG S NE + G+ SI P+ I+ +GI+ D +V ++G
Sbjct: 519 GEACKELDFPIVSGNVSLYNE---TNGE--SILPTPTIAGVGIIDDWLKVVTVGGMQDGD 573
Query: 627 AIYLVGKPQFSFGGSVFA-ELFGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCH 684
I LVG G S++ ++ I +G V +K+ + + + I +G + + H
Sbjct: 574 IIILVGPCGSHLGQSIYVRDILNIDTGTPPHVDLQLEKKNGQFVRDV---INRGFIHAAH 630
Query: 685 DLSEGGLAAALYEMCL---SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRS 741
D+S+GGLA AL EM + GI A+L + + A LFGE G L+ IK +
Sbjct: 631 DISDGGLAIALAEMVIKSGKGIRAKLSNI------SPRHAELFGEDQGRYLIAIKPNALN 684
Query: 742 AFEK--EMEGASIYEIGKTCGKA 762
+ ++ + S+ E+G G A
Sbjct: 685 SLKELSQTNMISLTELGTVEGDA 707
Score = 69.3 bits (168), Expect = 1e-09, Method: Composition-based stats.
Identities = 73/291 (25%), Positives = 126/291 (43%), Gaps = 30/291 (10%)
Query: 108 NAGIIEFD--EKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
+AG+I D +K+ ++F ++ +P+ G V R++ A P A TD L
Sbjct: 439 DAGVIRVDNNDKHALAFSSDVTPRYCEADPYEGGKQAVAECWRNISATGATPLAATDNLN 498
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVH-YHEAYASNPLVYC 224
FG+P+ P + + + + I+G+ + ++ P V+G V Y+E + L
Sbjct: 499 FGNPEKPE-------IMGQLVFA--IKGIGEACKELDFPIVSGNVSLYNETNGESILPTP 549
Query: 225 GCAGIAPRGKHRTKPSAGD----HIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQ 280
AG+ + G II L G G L + + +++ TG +Q
Sbjct: 550 TIAGVGIIDDWLKVVTVGGMQDGDIIILVGPCGSH-LGQSIYVRDILNIDTGTPPHVDLQ 608
Query: 281 IGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKIPVKY 338
+ +KK + + D ++G A D GG + A+ EM S G L+ I ++
Sbjct: 609 L-----EKKNGQFVRDVINRGFIHAAHDISDGGLAIALAEMVIKSGKGIRAKLSNISPRH 663
Query: 339 QGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
L E Q R +IA+ + L +L++L N + LT LG GDA+
Sbjct: 664 AEL------FGEDQGRYLIAIKPNALNSLKELSQTNMISLTELGTVEGDAL 708
>gi|148271907|ref|YP_001221468.1| phosphoribosylformylglycinamidine synthase II [Clavibacter
michiganensis subsp. michiganensis NCPPB 382]
gi|147829837|emb|CAN00760.1| phosphoribosylformylglycinamidine synthase II [Clavibacter
michiganensis subsp. michiganensis NCPPB 382]
Length = 786
Score = 282 bits (721), Expect = 7e-74, Method: Composition-based stats.
Identities = 232/784 (29%), Positives = 353/784 (45%), Gaps = 101/784 (12%)
Query: 15 AALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKK 74
AAL + E +R +RP T E + WSEHC +K+ K + G ++E KK
Sbjct: 43 AALGLTEGEYLRIREILGRRP-TSGELAMYSVMWSEHCSYKSSKKYLRQFGQKVSESMKK 101
Query: 75 AYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIE 134
++ +NAG+++ E + V+FK E+HNHPS IE
Sbjct: 102 D-------------------------LMVGMGENAGVVDVGEGWAVTFKIESHNHPSYIE 136
Query: 135 PFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGV 194
PF GA TGVGG++RD++ + ARP AV D L FG D P R++ GV+ G+
Sbjct: 137 PFQGAATGVGGIVRDIISMGARPVAVMDALRFGDIDDP---------DTARVVHGVVAGI 187
Query: 195 KDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHR-----TKPSAGDHIISLG 249
YGN +G+P + G ++ Y NPLV G+ +H G+ ++ G
Sbjct: 188 SFYGNCLGLPNIGGETYFDRVYQGNPLVNALAVGVL---RHEDLHLANARGVGNKVVLFG 244
Query: 250 GKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDC 309
+TG DG+ GA+ + A G +VQ+G+P +K + E ++ + L I D
Sbjct: 245 ARTGGDGIGGASILASDTFADGGPTKRPAVQVGDPFAEKVLIECCLELFAKDLVEGIQDL 304
Query: 310 GAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEAL 367
GA G S A E+AS G + L ++ ++ L E+ +SE+QERM+ V +KLE
Sbjct: 305 GAAGISCATSELASNGDGGMHIRLEEVLLRDPSLTAEEILMSESQERMMAVVQPEKLEGF 364
Query: 368 QKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPF 427
++ DVE + LG T L + + I+++ R + P +P
Sbjct: 365 LEVVRKWDVETSVLGEVTDTGRLVIDHHGERIVDVE---------PRTVAVDGPVYDRP- 414
Query: 428 IKYPEYKEPDLNAALKAVINHHAVNSKED----------------IVRLYDHEVQGGTVL 471
+ YP + + + + A + +D I YD V G T L
Sbjct: 415 VSYPTWIDALQADSASRLARPTAPDEIKDQFLQLLGSPNLADASWITDQYDRYVMGNTAL 474
Query: 472 RPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVA 531
+ P DA +++ ++ E +++ N R LDPY A A+ EA RN A
Sbjct: 475 --------SFPDDAGMVR-VDEESGLGFSVATDANGRFCQLDPYRGAQLALAEAYRNVAA 525
Query: 532 AGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSS 591
+GA P A+ D G P PE MW + L + P G S N+ +
Sbjct: 526 SGATP--VAVSDCLNFGSPEDPEVMWQFSRTVEGLADGCLELEIPVTGGNVSLYNQTGTQ 583
Query: 592 EGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPS 651
+I P+ ++ +G++ D+ R S ++ EG IYL+G + GS +A G
Sbjct: 584 -----AIHPTPVVGVLGVIDDVARRIPSGWQDEGDNIYLLGVTREELDGSAWA---GTVH 635
Query: 652 GESAAVPPFKKEAAELYKKLHSNIMKG----LVLSCHDLSEGGLAAALYEMCLS-GIGAE 706
VPP AAE K L S + G L+ S HDLS+GGL AL E + G+GA
Sbjct: 636 DHLGGVPPVVDLAAE--KDLASLVAAGATQSLIASAHDLSDGGLGQALAESVMRFGVGAR 693
Query: 707 LKED-FHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK--EMEGASIYEIGKTCGKA- 762
+ D R G +LF E+TG +LV + E+ F+ E G + IG T +A
Sbjct: 694 VWLDGIVQRDGVDAATALFSESTGRMLVTVPREDDVKFQGLCEGRGYPVLRIGVTDAQAP 753
Query: 763 GLKL 766
GL+L
Sbjct: 754 GLEL 757
>gi|149882852|ref|YP_001294830.1| putative phosphoribosyl formylglycinamidine (FGAM) synthase II
[Microbacterium phage Min1]
gi|148763483|gb|ABR10501.1| putative phosphoribosyl formylglycinamidine (FGAM) synthase II
[Microbacterium phage Min1]
Length = 775
Score = 282 bits (721), Expect = 7e-74, Method: Composition-based stats.
Identities = 226/735 (30%), Positives = 332/735 (45%), Gaps = 76/735 (10%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP T E + WSEHC +K+ K + G +++E ++
Sbjct: 47 RRP-TSGELAMYSVMWSEHCSYKSSKLYLKRFGQKVSDEMRER----------------- 88
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
++ NAG+I+ E + V+FKAE+HNHPS IEPF GA TGVGG++RD++
Sbjct: 89 --------LMVGMGQNAGVIDVGEGWAVTFKAESHNHPSFIEPFQGAATGVGGIVRDIIS 140
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP AV D L FG D P R++ GV G+ YGN +G+P + G +
Sbjct: 141 MGARPVAVMDALRFGAADDP---------DTARVVHGVTSGISFYGNCLGLPNIGGETVF 191
Query: 213 HEAYASNPLVYCGCAGIAPRG--KHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAS 270
Y +NPLV G+ K G+ ++ +TG DG+ GA+ +
Sbjct: 192 DAVYQANPLVNALAVGVLRHEDLKLANATGLGNKVVLFAARTGGDGIGGASILASDSFDE 251
Query: 271 TGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCD 328
G +VQ+G+P +K + E ++ L AI D GA G S A E+A+ G
Sbjct: 252 AGPTKRPAVQVGDPFAEKVLIECCLELYRDELVEAIQDLGAAGISCATSELAANGNSGMH 311
Query: 329 VDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDA 388
V L + ++ L E+ +SE+QERM+ V KL+A + +VE + LG TGD
Sbjct: 312 VSLDNVLLRDPSLTAEEILMSESQERMMAIVSPAKLDAFLAVTGKWEVETSVLGEVTGDG 371
Query: 389 VLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPK-------DGKPFIKYPEYKEPD-LNA 440
L + + + I+++ + P + A P D + +P L
Sbjct: 372 RLVIDWQGERIVDVDPSTVAVDGPVYERPVAYPTWLDALQADSAELLS--RSNDPAVLRE 429
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
A+++ + I YD+ V G T L + P DA +I+ ++ E A
Sbjct: 430 QFLALVSSPNLADTSWITNQYDYYVLGNTAL--------SFPDDAGMIR-VDEESGLGFA 480
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
I+ N R LDPYA A A+ EA RN GA P TA+ D G P PE MW
Sbjct: 481 IATDANGRYCQLDPYAGAQLALAEAYRNVAVTGAVP--TAVTDCLNFGSPENPEVMWQFG 538
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ + TP G SF N + V I P+ L+ +G++ D+ R S
Sbjct: 539 QTVDGLADGCYALGTPVTGGNVSFYN-----QTGDVPIHPTPLVGVLGLIDDVSRRIPSG 593
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKG-- 678
++ EG IYL+G GS +A+ G PP AAE K+L I
Sbjct: 594 WQDEGQNIYLLGVTSTELSGSAWADTVHDHLG---GRPPAVDLAAE--KRLAGLIAAARD 648
Query: 679 --LVLSCHDLSEGGLAAALYEMCLS-GIGAEL-KEDFHTRLGASKIASLFGETTGCLLVE 734
LV S HDLSEGGLA AL E + G+GA + + R G +LF E+TG ++V
Sbjct: 649 EWLVSSAHDLSEGGLAQALAEGVMRFGVGARVWLTELMERDGVDAATALFSESTGRVIVT 708
Query: 735 IKEENRSAFEKEMEG 749
+ E+ F EG
Sbjct: 709 VPREDDVKFRGLCEG 723
Score = 71.2 bits (173), Expect = 3e-10, Method: Composition-based stats.
Identities = 75/301 (24%), Positives = 126/301 (41%), Gaps = 29/301 (9%)
Query: 104 SFVDNAGIIEFDEKYEVSFKAET--HNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVT 161
SF D+AG+I DE+ + F T + ++P+ GA + R+V A P AVT
Sbjct: 461 SFPDDAGMIRVDEESGLGFAIATDANGRYCQLDPYAGAQLALAEAYRNVAVTGAVPTAVT 520
Query: 162 DVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS--- 218
D L FG P+ P G ++G+ D +G P G V ++
Sbjct: 521 DCLNFGSPENPEVMWQFGQ---------TVDGLADGCYALGTPVTGGNVSFYNQTGDVPI 571
Query: 219 NPLVYCGCAGIAPRGKHRTKPSA----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDV 274
+P G G+ R PS G +I LG + L G+ ++ V D G
Sbjct: 572 HPTPLVGVLGLIDDVSRRI-PSGWQDEGQNIYLLGVTSTE--LSGSAWADTVHDHLGGRP 628
Query: 275 AGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGE--MASALGCDVDLA 332
+ +K++A ++ ARD+ L S+ D GG + A+ E M +G V L
Sbjct: 629 PAVDLAA-----EKRLAGLIAAARDEWLVSSAHDLSEGGLAQALAEGVMRFGVGARVWLT 683
Query: 333 KIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRV 392
++ ++ G+ SE+ R+++ VP + + LC+ + +G + L V
Sbjct: 684 EL-MERDGVDAATALFSESTGRVIVTVPREDDVKFRGLCEGRGYPVLRIGVTDSEPTLEV 742
Query: 393 R 393
+
Sbjct: 743 Q 743
>gi|116493200|ref|YP_804935.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Pediococcus pentosaceus ATCC 25745]
gi|116103350|gb|ABJ68493.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Pediococcus pentosaceus ATCC 25745]
Length = 734
Score = 281 bits (720), Expect = 1e-73, Method: Composition-based stats.
Identities = 220/731 (30%), Positives = 337/731 (46%), Gaps = 86/731 (11%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K ++K + + + P
Sbjct: 45 AAMWSEHCAYKNSK------------------------PLLKQFPTTGSQILQGPG---- 76
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AGI++ V FKAE+HNHP+A+EP+ GA TGVGG+IRD+ + ARP A+ D L
Sbjct: 77 --EGAGIVDIGNNQAVVFKAESHNHPTAVEPYQGAATGVGGIIRDIFSMGARPIALMDSL 134
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG + H K ++ I G+ DYGN MGIPTV G + Y +NP++
Sbjct: 135 HFGELNDA---------HTKYLVDQTIAGIGDYGNCMGIPTVGGETTFDTIYQNNPVMNA 185
Query: 225 GCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG 282
C G+ + +A G+ I +G KTGRDG++GA F+S + + S+VQ+G
Sbjct: 186 MCVGLLDINDQQKGAAAGVGNAIYYVGAKTGRDGIQGAIFASTKF-SDEQETQRSAVQVG 244
Query: 283 EPIIQKKVAEV---LIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKIPVK 337
+P +K++ E LI + L I D GA G S+ EMA + G ++L +P +
Sbjct: 245 DPFAEKQLMEACLELIHNHSEYLV-GIQDMGAAGLISSSAEMAAKAGYGMHLNLDLVPQR 303
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
+ + P+EL LSE+QERM++ V A++ L + E +G T ++ F
Sbjct: 304 EEEMIPYELMLSESQERMLLCVKQGFEPAVEALFAKYESEAVKIGEVTAGDRYQLTFKGV 363
Query: 398 EIINLSC-GFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKED 456
++ ++ + P + P + + + K +L +A++ + K
Sbjct: 364 QVADVPVHALVDEAPVYHQPSQKPQHISETKKQQYQPKIENLTKTFQAMLQQPTIAHKGA 423
Query: 457 IVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYA 516
I YD +VQ T+ DAAV++ T+ K +A++ NPR LDPY
Sbjct: 424 IFERYDSQVQTNTI--------STTQSDAAVVRIRGTQ--KTLAMTTDANPRYLYLDPYY 473
Query: 517 AAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTP 576
A+ EA RN VA G P AI D G P PE+ + L + + +F TP
Sbjct: 474 GGQIAVSEAARNIVATGGIP--LAITDCLNFGSPEDPESFYELEQATKGMTEACKLFDTP 531
Query: 577 FISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQF 636
ISG S N E + I P+ ++ +G++ + + DFKK G IY++G+
Sbjct: 532 VISGNVSLYN-----ESNQQPIYPTPMVGMVGLIENPAWITTIDFKKSGDLIYILGETTA 586
Query: 637 SFGGSVFAELFGIPSGESAAVPPF------KKEAAELYKKLHSNIMKGLVLSCHDLSEGG 690
GS EL + G P F ++E EL +L I L+ S HDL+EGG
Sbjct: 587 ELNGS---ELQKMQLGHVEG-PLFNFDLRYEQEQQELLTQL---IHAELLNSAHDLAEGG 639
Query: 691 LAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGA 750
LA L E + +EL D T L A++ LF E +V I + + FE ++
Sbjct: 640 LAVGLAECVFA---SELGCDVKTNLTATE---LFAENQARFIVTIAPDKQKIFEAQVANR 693
Query: 751 SIYEIGKTCGK 761
+ IG+ GK
Sbjct: 694 ATL-IGQVGGK 703
>gi|119713259|gb|ABL97325.1| phosphoribosylformylglycinamidine synthase II [uncultured marine
bacterium HF10_12C08]
Length = 732
Score = 281 bits (718), Expect = 1e-73, Method: Composition-based stats.
Identities = 216/667 (32%), Positives = 333/667 (49%), Gaps = 52/667 (7%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+I+ D+ FK E+HNHPS +EP+ GA TGVGG++RDV + ARP A + L F
Sbjct: 77 ENAGVIDIDDGDVAVFKMESHNHPSFLEPYQGAATGVGGILRDVFTMGARPVANMNALRF 136
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P+ P K ++SGV+ G+ YGN +GIPTV G V++H +Y N LV
Sbjct: 137 GDPNHPKT---------KHLVSGVVGGIGGYGNCIGIPTVGGEVNFHPSYNGNILVNAMT 187
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
GIA + K + G+ ++ +G KTGRDG+ GAT +S D + + +VQ+G+P
Sbjct: 188 VGIAKKDKIFYSAAAGIGNPVVYVGSKTGRDGIHGATMASAEFDDDSEE-KKPTVQVGDP 246
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLA 342
+K + E ++ + AI D GA G +S+ EMAS +G D++L+K+P++ +
Sbjct: 247 FTEKLLLEACLELMKEDAIIAIQDMGAAGLTSSSIEMASKGNVGIDINLSKVPIRAANMT 306
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
+EL LSE+QERM++ + K E + + D+E +G T L + +E ++
Sbjct: 307 AYELMLSESQERMLMVIQPKKEELARSIFKKWDLEFEVIGEVTDTKKLILHMDGEEQASI 366
Query: 403 SCGFLHSGPPQRKLKAAPPKDGKPFIKY--PEYKEPDLNAALKAVINHHAVNSKEDIVRL 460
L P+ + + D P I + ++++ D+ + L +I+H + S++ I
Sbjct: 367 PINILVEDAPEYQ-RDYIINDPSPLISFESKDFEDKDILSDLLKMISHPNLCSRKWIWEQ 425
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YDH V TV+RP DAAV++ T K +AIS +P + Y
Sbjct: 426 YDHMVMADTVVRP--------GSDAAVVRVHGT--NKGIAISTDCSPTYCRHNSYEGGKH 475
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
A+ E RN VA+GA+P AI D G+P +PE M +E R + P ISG
Sbjct: 476 AVVETWRNIVASGAEP--IAITDCMNFGNPEKPEIMGQFVECIRGMGDACSKLNYPVISG 533
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
S NE + EG I P+ I +G++ D+ D K EG+ + L+G+ G
Sbjct: 534 NVSLYNE-TNGEG----IYPTPAIGGVGLIRDLSNTMTIDLKNEGNVLCLIGESNNHLGN 588
Query: 641 SVFAELFGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMC 699
S + + I S E P + + K + I K L+ S HD+ EGG+ A+ EMC
Sbjct: 589 SHYLSI--IQSREDGGTPSINLDDELKNGKFILDCIAKKLLKSVHDVGEGGVLVAIAEMC 646
Query: 700 LS---GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGAS----- 751
+S GI ++ +DF FGE LVE+ + E + ++
Sbjct: 647 ISGKQGIKIDITKDFLHGF-------FFGEDQARYLVEVSQNKLEQLEVDASKSAVKIER 699
Query: 752 IYEIGKT 758
I EIG T
Sbjct: 700 IGEIGGT 706
>gi|104774302|ref|YP_619282.1| Phosphoribosylformylglycinamidine synthase II [Lactobacillus
delbrueckii subsp. bulgaricus ATCC 11842]
gi|116514387|ref|YP_813293.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lactobacillus delbrueckii subsp. bulgaricus ATCC
BAA-365]
gi|103423383|emb|CAI98241.1| Phosphoribosylformylglycinamidine synthase II [Lactobacillus
delbrueckii subsp. bulgaricus ATCC 11842]
gi|116093702|gb|ABJ58855.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Lactobacillus delbrueckii subsp. bulgaricus ATCC
BAA-365]
Length = 740
Score = 281 bits (718), Expect = 2e-73, Method: Composition-based stats.
Identities = 233/737 (31%), Positives = 359/737 (48%), Gaps = 88/737 (11%)
Query: 45 AQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSS 104
A WSEHC +K K S+++ + K P +L
Sbjct: 47 AAMWSEHCSYKKSK------------------------SVLRLFPTKG------PRILQG 76
Query: 105 FVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
+ AG+++ + V FKAE+HNHP+A+EP+ GA TGVGG++RDV + ARP A D L
Sbjct: 77 PGEGAGVVDIGDGQAVVFKAESHNHPTAVEPYQGAATGVGGILRDVFSMGARPVATLDSL 136
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
FG D H + +++ + G+ YGN MGIPTV G + + + Y NP++
Sbjct: 137 HFGELDDA---------HTRWLLNETVAGIGGYGNCMGIPTVGGELTFDDIYKGNPVMNA 187
Query: 225 GCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG 282
G+ + G+ ++ +G KTGRDG+ GATF+S D S + S+VQ+G
Sbjct: 188 MSVGLLDVKDMQKGLAQGEGNAVMYVGAKTGRDGIHGATFASHSFD-SEHESQRSAVQVG 246
Query: 283 EPIIQKKVAEVLID--ARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKY 338
+P ++K + E ++ + I D GA G S+ EMAS G +++L +P +
Sbjct: 247 DPFMEKLLLEACLELTQKHADWLVGIQDMGAAGIVSSSSEMASEGKSGMELNLDLVPQRE 306
Query: 339 QGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTG--DAVLRVRFGE 396
G++ +E+ LSE+QERM++ V E ++K+ D D++ +GR T + VLR GE
Sbjct: 307 SGMSAYEIMLSESQERMLLCVKKGHEEDVKKIFDFYDLDAVVIGRITSGHNYVLR-HHGE 365
Query: 397 K----EIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVN 452
+ +L+ L +++ + KP + PE DL K ++ +
Sbjct: 366 VVCDIPVTSLTEDVLEEPSEEKQPQHMIDDAAKPAWE-PEIT--DLAKTYKQMLAQPTIA 422
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
SK + YD V+ TV+ P +D+ V++ T K +A++ N R L
Sbjct: 423 SKGMFTQTYDSMVRTSTVVGP--------GEDSGVLRVRGTH--KGIAMTTDGNGRFIYL 472
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALV 572
DP A+ EA N +A+GA+P AI D G+PN PE W L V
Sbjct: 473 DPEIGGKRAVVEAAGNIIASGAEP--LAITDCLNFGNPNEPEVFWELHHSVMGIAKACEV 530
Query: 573 FKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVG 632
+TP +SG S NE ++GK SI P+ ++ +G+V ++ + F++EG +YLVG
Sbjct: 531 LETPVVSGNVSLYNE---TDGK--SIYPTPMVGMVGLVKNLDHLVRDSFQEEGDDLYLVG 585
Query: 633 KPQFSFGGSVFAELFGIPSGES-AAVPPFKKEAAELY-KKLHSNIMKGLVLSCHDLSEGG 690
+ + GS EL + +GE ++ + + Y K+L + + G V S HDLSEGG
Sbjct: 586 QTGADYAGS---ELQKMLTGEIFGSLNDLDLDHIKDYQKRLLAQMEAGHVASAHDLSEGG 642
Query: 691 LAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEG 749
LA +L E GIGAE+ D + A LF ET G LV + E SA
Sbjct: 643 LAVSLAESSFGHGIGAEVACDLTS-------AELFSETPGRFLVSVPSE-YSAEFAAALA 694
Query: 750 ASIYEIGKTCGKAGLKL 766
A +IG+T G + LKL
Sbjct: 695 ADAVKIGQTAGDS-LKL 710
>gi|18976571|ref|NP_577928.1| phosphoribosylformylglycinamidine synthase subunit II [Pyrococcus
furiosus DSM 3638]
gi|22096008|sp|Q8U491|PURL_PYRFU Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|18892132|gb|AAL80323.1| phosphoribosylformylglycinamidine synthase II; (purL) [Pyrococcus
furiosus DSM 3638]
Length = 704
Score = 280 bits (717), Expect = 2e-73, Method: Composition-based stats.
Identities = 209/651 (32%), Positives = 332/651 (50%), Gaps = 60/651 (9%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
++AGII+FD+K + E+HNHPSA+EP+GGA TGVGG++RD++ + ARP A+ D + F
Sbjct: 58 EDAGIIKFDDKTWIVIGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRF 117
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P +N + + V++G+ DYGN++G+PTV G + E+ + LV C
Sbjct: 118 G-PLEKEKN--------RYLFEYVVKGIADYGNRIGVPTVGGETEFDESLDNYTLVNVAC 168
Query: 227 AGIAPRGKHR-----TKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQI 281
GI R +H T+P G ++ +G +TGRDG+ G TF+S + + + S+VQI
Sbjct: 169 IGIM-RPEHLVHSYVTEP--GLKLVIVGNRTGRDGIHGVTFASEELGENAEEEDRSAVQI 225
Query: 282 GEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQ 339
+P +K + E ++A G A+ D G GG + A EM G + K+P++
Sbjct: 226 PDPFTEKLLIEATLEAVYTGKVKALKDLGGGGLTCAASEMVGKRGFGAIIYADKVPLREP 285
Query: 340 GLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEI 399
G+ P E+ +SE+QERM+ A+ + +E L K+ + ++E + +G + V + +++
Sbjct: 286 GMTPLEVMISESQERMLFAIKPEDVEELGKIFEKYELEWSVVGEVIEEPKFIVYWKGRKV 345
Query: 400 INLSCGFLHSGP----PQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
L L + P P ++ + + E + L A + V V SK
Sbjct: 346 AELPIELLTNVPTIEWPMKEYRIE---------EDVETPQISLEEAFEKVWRSPNVISKR 396
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
+ YDHEVQG TV++P D+AV+K E G +AI+ NP L+PY
Sbjct: 397 WVWEQYDHEVQGRTVIKP--------GFDSAVLKINEEYG---LAITADGNPTHCYLNPY 445
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKT 575
A + E VRN V+ GA P A++DN P RPE W+ +E + + A F
Sbjct: 446 HGAMGVVVEVVRNLVSVGAKP--LALVDNLNFASPERPEVYWSFVETIKGLADAAKAFGL 503
Query: 576 PFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQ 635
++SG SF NE ++ + P+ +++ +G V + ++P +EG I L+G+ +
Sbjct: 504 AYVSGNVSFYNEVVNK-----PVKPTPVVAGVGKV-KLEKIPRG--PREGDLIGLIGETR 555
Query: 636 FSFGGSVFAELFGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAA 694
GGS + G+ G + V +K AE KL I +GLV HD+S GG+A A
Sbjct: 556 KELGGSELYRVLGVSKGIAPRVDLEVEKRNAESVLKL---IEEGLVSFVHDVSRGGVAVA 612
Query: 695 LYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEK 745
L E+ + +K + T L A F E+ G +V EEN A +K
Sbjct: 613 LAELS-TWFNVGIKSEITTSLLPLDFA--FSESHGRYIVTFPEENLEAVKK 660
>gi|119357078|ref|YP_911722.1| phosphoribosylformylglycinamidine synthase II [Chlorobium
phaeobacteroides DSM 266]
gi|119354427|gb|ABL65298.1| phosphoribosylformylglycinamidine synthase II [Chlorobium
phaeobacteroides DSM 266]
Length = 760
Score = 280 bits (717), Expect = 2e-73, Method: Composition-based stats.
Identities = 213/652 (32%), Positives = 325/652 (49%), Gaps = 46/652 (7%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ + ARP A + L F
Sbjct: 76 ENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTMGARPVASLNSLRF 135
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P + ++ GV+ G+ DYGN G+PTV G +++ E Y NPLV
Sbjct: 136 GSPKDS---------RVRYLVDGVVRGIGDYGNSFGVPTVGGEIYFEECYTGNPLVNAMS 186
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K T G+ ++ +G TGRDG+ GATF+S + ++ D SVQ+G+P
Sbjct: 187 VGLVEHHKTVSATAMGEGNPVLIVGSSTGRDGIHGATFASEDLSEASED-KRPSVQVGDP 245
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-------ALGCDVDLAKIPVK 337
+K + E ++A G + D GA G +S+ EM++ + G ++DL +P++
Sbjct: 246 FAEKLLLEATLEAIATGYVVGLQDMGAAGITSSTSEMSARGIEKTGSGGIEIDLDLVPIR 305
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR-FGE 396
+G+ +E+ LSE+QERM+I + ++ DV+ +G+ T D +LRV+ GE
Sbjct: 306 EEGMTAYEIMLSESQERMLIVALKGYEHKIIEVYQKWDVQAVVIGKVTADGLLRVKQHGE 365
Query: 397 K--EIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVN 452
EI +L+ L G P QR+ P K K + D++A +++ ++
Sbjct: 366 TVAEIPSLTL-VLGGGAPVYQREAIEKIPMTEKA--KLEADQTLDMHALALNLLSRPSIA 422
Query: 453 SKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLL 512
SK+ + R YD VQ T+ P G DAAVI+ + KK +A+ N R L
Sbjct: 423 SKQWVYRQYDSMVQTNTLT-----PVGVT--DAAVIRIKGS--KKGLAMKTDCNSRYVYL 473
Query: 513 DPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALV 572
+P A+ E RN GA P AI + G+P +PE +
Sbjct: 474 NPETGGKIAVAECARNIACTGARP--LAITNCLNFGNPYKPEVYFQFKASVEGMGAACRA 531
Query: 573 FKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVG 632
F TP G SF NE + G R +I P+ I +G++ DI GS F+ G AI L+G
Sbjct: 532 FNTPVTGGNVSFYNE-TTIGGGRTAIYPTPTIGMIGLLDDISSCVGSTFRFVGDAILLLG 590
Query: 633 KPQFSFGGSVFAEL-FGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGL 691
P+ + GS + + +G P +S +V + L + L S K LV S HD+S+GGL
Sbjct: 591 DPELTLDGSEYLVMQYGTPGIDSPSVD--LQHEKNLQELLISLAAKKLVHSAHDVSDGGL 648
Query: 692 AAALYEMCLSGIGAELKEDFHTR-LGASKI---ASLFGETTGCLLVEIKEEN 739
AL E + A L + +G+S LF E G +L+ I EN
Sbjct: 649 FTALAEKAIMKKDAPLGFAVNLEDVGSSDYRIQEHLFSEAQGRVLISIPPEN 700
>gi|67917641|ref|ZP_00511246.1| Phosphoribosylformylglycinamidine synthase II [Chlorobium limicola
DSM 245]
gi|67784670|gb|EAM44044.1| Phosphoribosylformylglycinamidine synthase II [Chlorobium limicola
DSM 245]
Length = 770
Score = 280 bits (717), Expect = 2e-73, Method: Composition-based stats.
Identities = 221/722 (30%), Positives = 334/722 (46%), Gaps = 67/722 (9%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
KR T E + WSEHC +K A ++KT +
Sbjct: 41 KRTPTFTELGIFSVMWSEHCSYKNSIA------------------------VLKTLPRDG 76
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+ + +NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+
Sbjct: 77 -----GALLTGAGEENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFT 131
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP A + L FG P P + ++ GV+ G+ DYGN G+PTV G +++
Sbjct: 132 MGARPVASLNSLRFGSPKDP---------RVRYLVDGVVRGIGDYGNSFGVPTVGGEIYF 182
Query: 213 HEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAS 270
E Y NPLV GI K T G+ ++ +G TGRDG+ GATF+S + +
Sbjct: 183 EECYTGNPLVNAMSVGIVEHHKTVSATAKGEGNPVLIVGSSTGRDGIHGATFASEDLSEA 242
Query: 271 TGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS------- 323
+ D SVQ+G+P +K + E ++A G + D GA G +S+ EM++
Sbjct: 243 SED-KRPSVQVGDPFAEKLLLEATLEAIATGYVVGLQDMGAAGLTSSTSEMSARGIEKTG 301
Query: 324 ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGR 383
G D+DL +P + +G++ +E+ LSE+QERM+I E + ++ DV+ +G
Sbjct: 302 RGGIDIDLDLVPAREEGMSAYEIMLSESQERMLIVAEKGFEERIIEVYRKWDVQAVVIGT 361
Query: 384 FTGDAVLRVRFGEKEIINLSCG--FLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAA 441
T D +R+R + + + L G P A K P + K DL+A
Sbjct: 362 VTSDNQIRIRQHGRIVAEIPAESLVLGGGAPVYIRDAVEKKPATPVARLIGDKHLDLHAL 421
Query: 442 LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAI 501
A+++ ++ SK+ + R YD VQ T+ P G DAAVI+ + +K +A+
Sbjct: 422 SLALLSRPSIASKQWVYRQYDSMVQTNTIT-----PTGT--SDAAVIRVKGS--RKGLAM 472
Query: 502 SNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIE 561
N R L+P A+ E RN +GA P AI + G+P +P+ +
Sbjct: 473 KTDCNARYVYLNPLKGGKIAVAECARNIACSGAKP--LAITNCLNFGNPYKPDVYFQFKT 530
Query: 562 MARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDF 621
F TP G SF NE S G+R +I P+ I +G++ DI V GS +
Sbjct: 531 SVEGMGEACRAFNTPVTGGNVSFYNE-TSIGGERTAIYPTPTIGMIGLLDDIDTVVGSTY 589
Query: 622 KKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVL 681
+ G AI L G P+ S GS + + G+ A + E L + L + K L+
Sbjct: 590 QHVGDAILLFGDPELSLEGSEYLVMQYDTPGQDAPDIDLRHE-KNLQELLVALASKKLLH 648
Query: 682 SCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASK----IASLFGETTGCLLVEIKE 737
S HD+S+GGL AL E + L D A LF E G +LV I
Sbjct: 649 SAHDISDGGLLVALAEKAIMNTDKPLGFDIDIENAAIHPFHIQQQLFSEAQGRVLVSIAP 708
Query: 738 EN 739
E+
Sbjct: 709 ES 710
>gi|145219660|ref|YP_001130369.1| phosphoribosylformylglycinamidine synthase II [Prosthecochloris
vibrioformis DSM 265]
gi|145205824|gb|ABP36867.1| phosphoribosylformylglycinamidine synthase II [Prosthecochloris
vibrioformis DSM 265]
Length = 761
Score = 280 bits (717), Expect = 2e-73, Method: Composition-based stats.
Identities = 197/617 (31%), Positives = 307/617 (49%), Gaps = 38/617 (6%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ + ARP A + L F
Sbjct: 76 ENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTMGARPVASLNSLRF 135
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P P + ++ GV+ G+ DYGN G+PTV G +++ + Y NPLV
Sbjct: 136 GSPKDP---------RVRYLVDGVVRGIGDYGNSFGVPTVGGEIYFEDCYTGNPLVNAMS 186
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ K T G+ ++ +G TGRDG+ GATF+S + ++ D SVQ+G+P
Sbjct: 187 VGLVEHHKTVSATAEGEGNPVLIVGSSTGRDGIHGATFASEDLSEASED-KRPSVQVGDP 245
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-------ALGCDVDLAKIPVK 337
+K + E ++A + G + + D GA G +S+ EM++ G +DL +P +
Sbjct: 246 FAEKLLLEATLEAIETGFVAGLQDMGAAGITSSTSEMSARGIEKNGTGGIMIDLDLVPAR 305
Query: 338 YQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEK 397
+G++ +E+ LSE+QERM+I E + + DV+ +GR T D +++++ +
Sbjct: 306 EEGMSAYEIMLSESQERMLIVAKKGHEEDIIAVYRKWDVQAVTVGRVTSDNNVKIQYRGE 365
Query: 398 EIINLSCG--FLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
+ ++ L G P +A K P + +L A+++ + SK
Sbjct: 366 LVADIPAESLVLGGGAPVYIREAVESKPDTPAAEMTPDSGLNLKDCAIALLSRPNIASKR 425
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
+ R YD VQ TV P G+ DAAVI+ T KKA+A+ N R L+P
Sbjct: 426 WVYRQYDSMVQTNTVT-----PVGHT--DAAVIRIKGT--KKALAMKTDCNSRYVYLNPL 476
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKT 575
A A+ E RN +GA P AI + G+P +PE + + + F T
Sbjct: 477 AGGKIAVAECARNIACSGARP--LAITNCLNFGNPYKPEVYFQFKTSVQGMGDACRAFST 534
Query: 576 PFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQ 635
P G SF NE + G R +I P+ I +G++ DI + GS F G AI L G P
Sbjct: 535 PVTGGNVSFYNES-THGGGRAAIYPTPTIGMIGLLEDIDNLVGSTFTTSGDAIILFGDPD 593
Query: 636 FSFGGSVFAEL-FGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAA 693
+ GS + + +G P ++ + +K +L L K L+ S HD+S+GGL
Sbjct: 594 LNLDGSEYQVMQYGTPGTDAPDINLDHEKNLQDLLVALAG---KKLLHSAHDVSDGGLFV 650
Query: 694 ALYEMCLSGIGAELKED 710
AL E + A L D
Sbjct: 651 ALAEKAIMNETARLGFD 667
>gi|67939860|ref|ZP_00532344.1| Phosphoribosylformylglycinamidine synthase II [Chlorobium
phaeobacteroides BS1]
gi|67913919|gb|EAM63283.1| Phosphoribosylformylglycinamidine synthase II [Chlorobium
phaeobacteroides BS1]
Length = 799
Score = 280 bits (716), Expect = 3e-73, Method: Composition-based stats.
Identities = 226/748 (30%), Positives = 350/748 (46%), Gaps = 85/748 (11%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + WSEHC +K A ++KT ++
Sbjct: 70 RTPTFTELGIFSVMWSEHCSYKNSIA------------------------VLKTLPREG- 104
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
+ S+ +NAG+++ + V+FK E+HNHPSA+EP+ GA TGVGG+ RD+ +
Sbjct: 105 ----GALLTSAGEENAGLVDIGDNLAVAFKIESHNHPSAVEPYQGAATGVGGIHRDIFTM 160
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P + ++ GV+ G+ DYGN G+PTV G +++
Sbjct: 161 GARPVASLNSLRFGSPKDP---------RVRYLVDGVVRGIGDYGNSFGVPTVGGEIYFE 211
Query: 214 EAYASNPLVYCGCAGIAPRGKHRTKPSA-----GDHIISLGGKTGRDGLRGATFSSMVMD 268
+AY NPLV G+ +H+ SA G+ ++ +G TG+DG+ GATF+S +
Sbjct: 212 DAYTGNPLVNAMSVGLV---EHQNTVSATAEGEGNPVLIVGSSTGKDGIHGATFASEDLS 268
Query: 269 ASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS----- 323
++ D SVQ+G+P +K + E ++A G + + D GA G +S+ EM+S
Sbjct: 269 EASED-KRPSVQVGDPFAEKLLLEATLEAIATGYVAGLQDMGAAGLTSSTSEMSSRGIST 327
Query: 324 --ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
+ G ++DL +P++ ++ +E+ LSE+QERM+I + + + D+ +
Sbjct: 328 NGSGGIEIDLDFVPIRENDMSAYEIMLSESQERMLIVAEKGHEQNIIDVYSKWDIHAVII 387
Query: 382 GRFTGDAVLRVRFGEKEIINLSCG--FLHSGPPQRKLKAAPPK-DGKPFIKYPEYKEPDL 438
G T D LRVR + + L G P +A K D P P+ DL
Sbjct: 388 GTVTADNQLRVRHHGAVVAEIPAESLVLGGGAPVYIREAVEKKPDNPPADPRPD-SSIDL 446
Query: 439 NAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKA 498
A +++ + SK+ + + YD VQ TV P G DAAVI+ T KKA
Sbjct: 447 RDASLRLLSRPNIASKQWVYQQYDSMVQTNTVT-----PTGQT--DAAVIRIKGT--KKA 497
Query: 499 VAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWA 558
+A+ N R L+P A+ E RN +GA P AI + G+P +P+ +
Sbjct: 498 LAMKTDCNGRYVYLNPKKGGMIAVAECARNIACSGATP--LAITNCLNFGNPYKPDVYYQ 555
Query: 559 LIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPG 618
F TP G SF NE S +I P+ +I +G++ DI + G
Sbjct: 556 FKASVEGMGEACRAFNTPVTGGNVSFYNE---SSLTGTAIYPTPVIGMIGLLEDIEHLTG 612
Query: 619 SDFKKEGSAIYLVGKPQFSFGGSVFAEL-FGIPSGESAAVPPFKKEAAELYKKLHSNIMK 677
S F G AI L+G P + GS + + +G P G+ A E L K L
Sbjct: 613 STFMHPGDAILLLGNPPLTLDGSEYLVMQYGTP-GQDAPAFDLDHE-LNLQKLLVGLAQS 670
Query: 678 GLVLSCHDLSEGGLAAALYEMCLS------GIGAELKEDFHTRLGASKIASLFGETTGCL 731
GL+ S HD+S+GGL AL E + G+ L+++ T ++ LF E G +
Sbjct: 671 GLMSSAHDISDGGLFTALVEKSIMDSTNPLGMAVNLEQEITTPSFIQEL--LFSEAQGRV 728
Query: 732 LVEIKEEN--RSAFEKEMEGASIYEIGK 757
L+ ++ EN R + E +G IG+
Sbjct: 729 LLSVRPENAARVIEKAEHQGVPAKVIGQ 756
>gi|149184814|ref|ZP_01863132.1| phosphoribosylformylglycinamidine synthase subunit II
[Erythrobacter sp. SD-21]
gi|148832134|gb|EDL50567.1| phosphoribosylformylglycinamidine synthase subunit II
[Erythrobacter sp. SD-21]
Length = 744
Score = 279 bits (714), Expect = 4e-73, Method: Composition-based stats.
Identities = 235/765 (30%), Positives = 359/765 (46%), Gaps = 123/765 (16%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + + K P +AP
Sbjct: 34 ELGIFSVMWSEHCSYKSSRLHL------------KKLP------------------TEAP 63
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 64 WVICGPGENAGVIDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVA 123
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG PD P K ++ GV+ G+ YGN +G+PTV G +++ AY N
Sbjct: 124 NANALRFGRPDHPKM---------KHLVQGVVAGIGGYGNCVGVPTVCGETNFNPAYDGN 174
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A K + G+ I+ +G KTGRDG+ GAT +S + D
Sbjct: 175 ILVNAMTVGVADADKIFYSAATGVGNPIVYVGSKTGRDGIHGATMASADFEED-ADAKRP 233
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIP 335
+VQ+G+P +K + E ++ AI D GA G +S+ EMA+ G +D+ K+P
Sbjct: 234 TVQVGDPFTEKLLIEACLELMATDAIVAIQDMGAAGLTSSSVEMATNGKAGIRLDMDKVP 293
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ +G+ P+E+ LSE+QERM++ + K + + +++ +G T + + FG
Sbjct: 294 CREEGMTPYEMMLSESQERMLMVLKPGKEAMAAAIFEKWELDFAVIGEVTDTQHMVLEFG 353
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYK-------------EPDLNAAL 442
+ + ++ G L A P+ +P++ EY D+ L
Sbjct: 354 GEVVCDIPLG---------PLAADAPEYDRPYLSKEEYTTWAGVAPMTNRPDTDDVGGDL 404
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
++ ++S++ I YD +V T+ DA V++ T KKA+AIS
Sbjct: 405 MKLLASPNLSSRKWISEQYDSQVGADTL---------QTGGDAGVVRVHGT--KKALAIS 453
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM----WA 558
PR PY AI EA RN A GA P A+ + +P RPE M A
Sbjct: 454 TDCTPRYVHAAPYEGGKQAIAEAYRNLCAVGARP--LAVTNCLNFANPQRPEIMAQFVHA 511
Query: 559 LIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPG 618
L M R+C V P +SG S NE ++ G +I P+ I +G++ D +
Sbjct: 512 LEGMGRACR----VLDFPVVSGNVSLYNESKATGGGS-AILPTPAIGGVGLIDDYDHMMT 566
Query: 619 SDFKKEGSAIYLVGKPQFS--------FGGSVF-AELFGIPSGESAAVPP----FKKEAA 665
FK EG AIYL+ +++ G S++ E+ G G + PP +K A
Sbjct: 567 MPFKAEGEAIYLIHAEEWATADPERSHLGKSLWLKEIHGRDEGRT---PPTDLTVEKNAG 623
Query: 666 ELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAEL--KEDFHTRLGASKIAS 722
++ +L I GLV + HD+S+GGLA AL EM ++ GIGA++ E++ SK A
Sbjct: 624 KIILQL---IADGLVSAVHDVSDGGLAIALAEMAIAGGIGADVDWNEEY------SKAAW 674
Query: 723 LFGETTGCLLVEIKE-----ENRSAFEKEMEGASI--YEIGKTCG 760
FGE G ++ + + E + + E ASI IGKT G
Sbjct: 675 WFGEDQGRYVITVPDTQALNEALAEGTENDETASIGFRRIGKTGG 719
>gi|119964003|ref|YP_946435.1| phosphoribosylformylglycinamidine synthase II [Arthrobacter
aurescens TC1]
gi|119950862|gb|ABM09773.1| phosphoribosylformylglycinamidine synthase II [Arthrobacter
aurescens TC1]
Length = 769
Score = 279 bits (714), Expect = 5e-73, Method: Composition-based stats.
Identities = 223/749 (29%), Positives = 343/749 (45%), Gaps = 98/749 (13%)
Query: 27 EFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIK 86
E K R T AE + WSEHC +K+ K + G +TEE KK
Sbjct: 39 EIVKVLGRRPTGAELAMYSVMWSEHCSYKSSKNHLRQFGEKVTEEMKKD----------- 87
Query: 87 TYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGV 146
+L +NAG+ + + V+FK E+HN PS +EP+ GA TG+GG+
Sbjct: 88 --------------MLVGIGENAGVTNLGDGWAVTFKIESHNSPSFVEPYQGAATGIGGI 133
Query: 147 IRDVMGVSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGI 203
+RD++ + ARP AV D L FG HPDT R++ G + G+ YGN +G+
Sbjct: 134 VRDIISMGARPVAVMDPLRFGAIDHPDT------------ARVMHGAVAGIGGYGNCLGL 181
Query: 204 PTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGAT 261
P + G + + Y NPLV G+ R ++ G+ ++ G +TG DG+ GA+
Sbjct: 182 PNIGGEMVFDSVYQGNPLVNALAVGVMRHEDIRLANASGKGNKVVLFGARTGGDGIGGAS 241
Query: 262 FSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEM 321
+ T +VQ+G+P +K + E ++ L I D GA G S A E+
Sbjct: 242 VLASESFDDTKPSKRPAVQVGDPFAEKVLIECCLELFKGSLVEGIQDLGAAGISCATSEL 301
Query: 322 ASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELT 379
AS G +V+L + ++ L P E+ +SE+QERM+ V + + A + + D VE +
Sbjct: 302 ASNGDGGMEVELTSVLLRDPTLTPGEILMSESQERMMAVVTPENIAAFEAVMDKWAVEYS 361
Query: 380 NLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP--- 436
LG T L + + + I+++ P+ P D +PF + PE+++
Sbjct: 362 WLGEVTDTGRLIITWEGEVIVDVD--------PRTVAHDGPVYD-RPFAR-PEWQDSVQA 411
Query: 437 -----------------DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEG 479
+L AA+ ++ + SK I + YD V G T +
Sbjct: 412 NSFTGSVEDAGRPSAPTELAAAVTELVASPNMCSKAWITKQYDRYVGGNTAMA------- 464
Query: 480 NVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKT 539
P DA V++ E G VA++ N R L+PY A A+ EA RN +GA P
Sbjct: 465 -FPDDAGVVRVDEETG-LGVALATDANGRYTYLEPYQGAQLALAEAYRNVATSGAVP--M 520
Query: 540 AILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIP 599
A+ D G P P+ MW L E R + + P G S N+ ++ I
Sbjct: 521 AVSDCLNFGSPEDPDVMWQLAEAIRGLSDACMELGIPVTGGNVSLYNQTGTT-----PIH 575
Query: 600 PSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPP 659
PS +++ +G + D+ R S ++++G AIYL+G GS ++ L G +PP
Sbjct: 576 PSPVVAVLGKLDDVARRTPSGWREDGQAIYLLGTTAAELDGSEWSNL----RGHLGGLPP 631
Query: 660 FKKEAAE--LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELK-EDFHTRL 715
AAE L + L + G+V + HDLSEGGLAAAL E L G+GA + E+ R
Sbjct: 632 KVDLAAERALGEILINASRDGMVDAAHDLSEGGLAAALVESSLRYGVGARIALEELMERD 691
Query: 716 GASKIASLFGETTGCLLVEIKEENRSAFE 744
G +LF E+ +V + F+
Sbjct: 692 GVDLFTALFSESQARAIVSVPRSEEVRFK 720
Score = 71.6 bits (174), Expect = 2e-10, Method: Composition-based stats.
Identities = 76/311 (24%), Positives = 135/311 (43%), Gaps = 36/311 (11%)
Query: 75 AYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEK--YEVSFKAETHNHPSA 132
A P +C K +I K D +F D+AG++ DE+ V+ + + +
Sbjct: 439 ASPNMCS----KAWITKQYDRYVGGNTAMAFPDDAGVVRVDEETGLGVALATDANGRYTY 494
Query: 133 IEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIE 192
+EP+ GA + R+V A P AV+D L FG P+ P ++ I
Sbjct: 495 LEPYQGAQLALAEAYRNVATSGAVPMAVSDCLNFGSPEDP---------DVMWQLAEAIR 545
Query: 193 GVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK----HRTKPSA----GDH 244
G+ D ++GIP G V + + P+ +A GK R PS G
Sbjct: 546 GLSDACMELGIPVTGGNVSLYNQTGTTPIHPSPV--VAVLGKLDDVARRTPSGWREDGQA 603
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
I LG L G+ +S++ G + G ++ + ++ + E+LI+A G+
Sbjct: 604 IYLLGTTAAE--LDGSEWSNL-----RGHLGGLPPKV-DLAAERALGEILINASRDGMVD 655
Query: 305 AITDCGAGGYSSAVGE--MASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPND 362
A D GG ++A+ E + +G + L ++ ++ G+ + SE+Q R +++VP
Sbjct: 656 AAHDLSEGGLAAALVESSLRYGVGARIALEEL-MERDGVDLFTALFSESQARAIVSVPRS 714
Query: 363 KLEALQKLCDA 373
+ + +C A
Sbjct: 715 EEVRFKDMCTA 725
>gi|124005761|ref|ZP_01690600.1| phosphoribosylformylglycinamidine synthase II [Microscilla marina
ATCC 23134]
gi|123988829|gb|EAY28435.1| phosphoribosylformylglycinamidine synthase II [Microscilla marina
ATCC 23134]
Length = 755
Score = 279 bits (714), Expect = 5e-73, Method: Composition-based stats.
Identities = 236/782 (30%), Positives = 373/782 (47%), Gaps = 95/782 (12%)
Query: 3 DEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKID 62
+E+L + + L I E I+E R E + WSEHC +K+
Sbjct: 2 EEQLTTVETAMQLGLLIEEFEKIKELLG---RTPNFTELSAFSVMWSEHCCYKS------ 52
Query: 63 IDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLS-SFVDNAGIIEFDEKYEVS 121
SI+ ++KK +P +L+ + +NAG+++ +
Sbjct: 53 --------------------SIL--WLKKLPKS--SPRMLAEAGEENAGLVDIGNGLACA 88
Query: 122 FKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTL 181
FK E+HNHPSAIEP+ GA TGVGG+ RD+ + ARP A + L FG D
Sbjct: 89 FKIESHNHPSAIEPYQGAATGVGGINRDIFTMGARPIAQLNTLRFGDIDLEKT------- 141
Query: 182 HPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPS- 240
K ++ GV++G+ DYGN G+PTV G V++ +Y +NPLV AGI K + +
Sbjct: 142 --KHLLRGVVKGIGDYGNAFGVPTVGGEVYFDSSYNTNPLVNAFSAGIVETDKIASAIAL 199
Query: 241 -AGDHIISLGGKTGRDGLRGATFSSM-VMDASTGDVAGSSVQIGEPIIQKKVAEVLIDAR 298
G+ + +G TG+DG+ GA F+S + + S D+ SVQ+G+P +K + E ++
Sbjct: 200 GVGNPVFIVGSATGKDGIHGAAFASKDITEDSAKDL--PSVQVGDPFQEKLLLEATLEVI 257
Query: 299 DQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMV 356
G I D GA G + EM++ G D+DL K+P++ + + P+E+ LSE+QERM+
Sbjct: 258 ATGNVVGIQDMGAAGIICSSSEMSAKGEHGMDIDLDKVPLRQENMLPFEILLSESQERML 317
Query: 357 IAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKL 416
+ V K + + + D D+ +G T VRF +K G L + P L
Sbjct: 318 VVVEKGKEQEILDIFDKWDLNCAEIGTVTESN--NVRFFQK-------GELVADVPANAL 368
Query: 417 ---KAAPPKD---GKP--FIKYPEYK-----EP-DLNAALKAVINHHAVNSKEDIVRLYD 462
AP + +P F +Y +K EP D A + ++ H + S++ I YD
Sbjct: 369 VLGGDAPIYEHSYTEPDYFQQYKHFKTEDVPEPTDYAAVAQFLMKHPNIVSRQWIYEQYD 428
Query: 463 HEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAI 522
V GT N P DAAV+ + +A+ IS N R DP A A+
Sbjct: 429 SMV--GTA-----NASTNSPADAAVVHIKGAD--QAIVISVDCNGRYVQADPKIGAMIAV 479
Query: 523 DEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKD 582
E+ RN V AG +P AI +N G+P E W ++ + + +TP G
Sbjct: 480 CESARNVVCAGGNP--VAITNNLNFGNPYNQEVYWQFVQSVKGIIDACEKLETPVTGGNV 537
Query: 583 SFNNE--YLSSEGKRVS--IPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SF N+ +S EG V+ + P+ I +G++ ++ DFK G IY++G+P+
Sbjct: 538 SFYNQASTVSKEGGNVTNAVLPTPTIGMLGLMDNLEHRMTLDFKNVGDIIYVIGEPKNDI 597
Query: 639 GGSVFAELFGIPSGESAAVPPFKKEAA-ELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
GS + L + + ++ P F EA +L + + + I + S HD+S+GGL L E
Sbjct: 598 AGSEY--LTSYHNFKESSAPHFDLEAEYDLQQTVKALIRDKQIQSAHDISDGGLFVTLAE 655
Query: 698 MCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASI--YE 754
+ +G + F + K A LFGE+ ++V IK E++ FE M+ S+ +E
Sbjct: 656 SAMPRDLGFSILTTF-DEIDVRKDAFLFGESQSRVVVTIKAEDQDRFEDFMKEQSVPFFE 714
Query: 755 IG 756
+G
Sbjct: 715 VG 716
>gi|152968011|ref|YP_001363795.1| phosphoribosylformylglycinamidine synthase II [Kineococcus
radiotolerans SRS30216]
gi|151362528|gb|ABS05531.1| phosphoribosylformylglycinamidine synthase II [Kineococcus
radiotolerans SRS30216]
Length = 772
Score = 278 bits (710), Expect = 1e-72, Method: Composition-based stats.
Identities = 238/745 (31%), Positives = 352/745 (47%), Gaps = 82/745 (11%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E IRE +RP T AE + WSEHC +K+ K + G +TE+ K +
Sbjct: 34 EYARIREILG--RRP-TGAELAMYSVMWSEHCSYKSSKVHLRTFGDHITEDMKAS----- 85
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
++ +NAG+++ + + V+FK E+HNHPS IEP+ GA
Sbjct: 86 --------------------LMVGIGENAGVVDIGQGWAVTFKVESHNHPSFIEPYQGAA 125
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFG---HPDTPAENVPKGTLHPKRIISGVIEGVKDY 197
TGVGG+IRD+M + ARP AV D L FG HPDT R++ GV+ GV Y
Sbjct: 126 TGVGGIIRDIMAMGARPIAVMDSLRFGAIDHPDT------------ARVVPGVVSGVGGY 173
Query: 198 GNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGR 254
GN +G+P + G V + Y NPLV C G A R + +A G+ ++ G +TG
Sbjct: 174 GNCIGLPNIGGEVVFDPTYQGNPLVNALCVG-ALRHEDLHLANARGVGNLVVLFGARTGG 232
Query: 255 DGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGY 314
DG+ G + + STG +VQ+G+P +K + E ++ GL I D G G
Sbjct: 233 DGIGGVSVLASETFDSTGPSKRPAVQVGDPFQEKVLIECCLELFHAGLVEGIQDLGGAGL 292
Query: 315 SSAVGEMASA--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCD 372
S A E+ASA G V L ++P++ L+P E+ +SE+QERM+ V + +EA +
Sbjct: 293 SCATSELASAGDGGMLVHLDRVPLRDPSLSPEEILMSESQERMMAIVTPENVEAFLAVTA 352
Query: 373 ANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFL-HSGPPQRKLKAAPPK------DGK 425
DVE LG T L V++ + ++++ + H GP ++ A P D
Sbjct: 353 KWDVEAAVLGEVTDGEHLVVQWHGETVVDVPPRTVAHDGPVYQRPYARPASQDALQADTP 412
Query: 426 PFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDA 485
+ P E +L A L ++ + S+ + YD V G T L P DA
Sbjct: 413 DSLPRPGTGE-ELRATLLRMVASPNLCSRAWVTDQYDRYVLGRTALA--------TPDDA 463
Query: 486 AVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNF 545
V++ ++ E VA+S N R LDP AA A+ EA RN AAGA P A+ D
Sbjct: 464 GVVR-VDEETNLGVALSLDGNGRFARLDPRTGAALALAEAYRNVAAAGAKP--LAVTDCL 520
Query: 546 CLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLIS 605
G P P MW E + P G S N+ EG ++ P+ +I
Sbjct: 521 NFGSPEDPGVMWQFAEAVQGLALACEELGVPVTGGNVSLYNQ-TGDEGLDSAVLPTPVIG 579
Query: 606 AMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAA 665
+G++ D+ R S +++ G +YL+G + FGGS +A G +PP A
Sbjct: 580 VLGVLDDVRRRTPSGWREAGQNVYLLGTTRDEFGGSEWA---WAEHGHLGGLPPVLDLAH 636
Query: 666 ELYKKLHSNIM-----KGLVLSCHDLSEGGLAAALYEMCLS-GIGAEL-KEDFHTRLGAS 718
E KL ++++ GLV + HDLS+GGLA AL E L G+G + ++ R G
Sbjct: 637 E---KLLADVLVQCSRDGLVDAAHDLSDGGLAQALAESALRFGVGVRVWLDELLERDGID 693
Query: 719 KIASLFGETTGCLLVEIKEENRSAF 743
+LF E+ G +V + E F
Sbjct: 694 AFTALFSESAGRAIVSVPREEEVRF 718
Score = 65.5 bits (158), Expect = 1e-08, Method: Composition-based stats.
Identities = 71/294 (24%), Positives = 124/294 (42%), Gaps = 39/294 (13%)
Query: 107 DNAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVL 164
D+AG++ DE+ V+ + + + ++P GA + R+V A+P AVTD L
Sbjct: 461 DDAGVVRVDEETNLGVALSLDGNGRFARLDPRTGAALALAEAYRNVAAAGAKPLAVTDCL 520
Query: 165 CFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN----- 219
FG P+ P G + + ++G+ ++G+P G V +
Sbjct: 521 NFGSPEDP------GVMWQ---FAEAVQGLALACEELGVPVTGGNVSLYNQTGDEGLDSA 571
Query: 220 --PLVYCGCAGIAPRGKHRTKPS----AGDHIISLGGKTGRDGLRGATFSSMVMDASTGD 273
P G G+ + RT PS AG ++ LG T RD G+ ++ A G
Sbjct: 572 VLPTPVIGVLGVLDDVRRRT-PSGWREAGQNVYLLG--TTRDEFGGSEWAW----AEHGH 624
Query: 274 VAGSSVQIGEPII----QKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDV 329
+ G P++ +K +A+VL+ GL A D GG + A+ E A G V
Sbjct: 625 LGGLP-----PVLDLAHEKLLADVLVQCSRDGLVDAAHDLSDGGLAQALAESALRFGVGV 679
Query: 330 DL-AKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
+ ++ G+ + SE+ R +++VP ++ +C A + +G
Sbjct: 680 RVWLDELLERDGIDAFTALFSESAGRAIVSVPREEEVRFTDMCTARGLAHVRIG 733
>gi|118588569|ref|ZP_01545977.1| phosphoribosylformylglycinamidine synthase subunit II [Stappia
aggregata IAM 12614]
gi|118438555|gb|EAV45188.1| phosphoribosylformylglycinamidine synthase subunit II [Stappia
aggregata IAM 12614]
Length = 732
Score = 277 bits (708), Expect = 2e-72, Method: Composition-based stats.
Identities = 230/739 (31%), Positives = 349/739 (47%), Gaps = 81/739 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ K + K P
Sbjct: 32 REPTFTELGIFSAMWNEHCSYKSSKKWL------------KTLP---------------- 63
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
+ P VL +NAG+++ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 64 --TEGPRVLQGPGENAGVVDIGDGQAVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTM 121
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG PD P + ++SGV+ GV YGN G+PTV G V +H
Sbjct: 122 GARPVAAMNALRFGEPDHP---------RTRHLVSGVVSGVGGYGNSFGVPTVGGEVEFH 172
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV AG+A G ++ LG KTGRDG+ GAT +S D T
Sbjct: 173 ARYNGNCLVNAFAAGLAKSDAIFLAKAEGVGLPVVYLGAKTGRDGVGGATMASAEFD-DT 231
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ + G AI D GA G + + EM ++ LG ++
Sbjct: 232 IEEKRPTVQVGDPFTEKCLLEACLELMETGAVIAIQDMGAAGLTCSAVEMGASGDLGIEL 291
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL K+PV+ + ++ +E+ LSE+QERM++ + +K + + ++ +G+ T
Sbjct: 292 DLDKVPVREEQMSAYEMMLSESQERMLMVLRPEKEHEAEAIFKKWGLDFAIVGKTTDTLR 351
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINH 448
V+ + + +L L P+ PK +P + E +EP D ALK ++ +
Sbjct: 352 FIVKHQGEVVADLPIKELGDEAPEYDRPWVEPKK-RPVLSPSEIEEPADYAEALKTLVGN 410
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
+S+ + YD +QG + P DA VI+ T +K ++ S + PR
Sbjct: 411 ANGSSRRWVYEQYDTLIQGNSAATP--------GGDAGVIRVEGT--RKGLSFSVDVTPR 460
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
DP+ A+ E RN A G++P A DN G+P +PE M + +
Sbjct: 461 YCEADPFEGGKQAVAEVWRNLTAVGSEP--LAATDNLNFGNPEKPEIMGQFVGCIKGIGE 518
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
P +SG S NE + G+ +I P+ I +G++PD+ G+ F EG AI
Sbjct: 519 ACRELDFPIVSGNVSLYNE---THGE--AILPTPAIGGVGLLPDVTVRAGAAFVNEGDAI 573
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPF----KKEAAELYKKLHSNIMKGLVLSCH 684
L+G G S + L I E A PP +K L ++L I V + H
Sbjct: 574 LLIGGNGTHLGASQY--LADILGREEGAPPPVDLAAEKRRGTLVRQL---IGAARVTAVH 628
Query: 685 DLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAF 743
D+S GGL AL EM + SGIGA++K D A+LFGE G +V + E+ A
Sbjct: 629 DISSGGLGVALAEMAMASGIGAKVKID------GPAHAALFGEDQGRYVVTVAEDKLEAV 682
Query: 744 EKEM--EGASIYEIGKTCG 760
+++ G + +IG T G
Sbjct: 683 LEDILDGGVDVQQIGTTGG 701
>gi|33239455|ref|NP_874397.1| phosphoribosylformylglycinamidine synthase subunit II
[Prochlorococcus marinus subsp. marinus str. CCMP1375]
gi|33236980|gb|AAP99049.1| Phosphoribosylformylglycinamidine (FGAM) synthase [Prochlorococcus
marinus subsp. marinus str. CCMP1375]
Length = 801
Score = 277 bits (708), Expect = 2e-72, Method: Composition-based stats.
Identities = 217/747 (29%), Positives = 340/747 (45%), Gaps = 96/747 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
KR E WSEHC ++ + S++ +
Sbjct: 43 KRSPNRTELGMFGVMWSEHCCYRNSR------------------------SLLSNFPTTG 78
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+ + P +NAG+++ E ++FK E+HNHPSAIEPF GA TGVGG++RD+
Sbjct: 79 KNILVGPG------ENAGVVDLGEGQRLAFKIESHNHPSAIEPFQGAATGVGGILRDIFT 132
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP A+ + L FG DTP NV ++ GV+ G+ YGN +G+PTV G V +
Sbjct: 133 MGARPIALLNSLRFGPLDTPI-NVG--------LLEGVVSGIAHYGNCVGVPTVGGEVAF 183
Query: 213 HEAYASNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATF-SSMVMDA 269
++Y+ NPLV GI + + G +I +G TGRDG+ GA+F SS + A
Sbjct: 184 DKSYSGNPLVNAMALGIMETKEIVCSGAKGIDFPVIYVGSTTGRDGMGGASFASSELTQA 243
Query: 270 STGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGC 327
S D +VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G
Sbjct: 244 SIDD--RPAVQVGDPFLEKGLIEGCLEAFKTGYVVAAQDMGAAGLTCSCSEMAAKGGVGI 301
Query: 328 DVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGD 387
++DL +P + + + +E LSE+QERM+ V K E + ++ +G+ +
Sbjct: 302 ELDLDLVPAREKNMTAYEFLLSESQERMLFVVEPGKEELIMNKFRKWGLQAKVVGKVLEE 361
Query: 388 AVLRVRFGEKEIINLSCGFLHSGPPQRK--LKAAPPKDGKPFIKYPEYKEP--------- 436
++RV ++ ++NL L P K L PP K K+ E P
Sbjct: 362 NIVRVIHEKQIVVNLPADSLAEDTPVNKHELLEEPPGFIKDHWKWDETSLPKVSIKGVHF 421
Query: 437 -------DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
D N + +++ + SK I YD++VQ T++ P G DAA+I+
Sbjct: 422 KENNTILDWNQIILRLLDDPTIASKRWIYNQYDYQVQNNTIIAPGIG-------DAALIR 474
Query: 490 PMETEGK-----KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDN 544
E E + + +A R LDP A +A+ EA RN GA P A+ DN
Sbjct: 475 LREIENQNQNSNRGIAAVVDCPNRWVALDPERGAIAAVAEASRNISCVGAKP--LAVTDN 532
Query: 545 FCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLI 604
P P W L + + +V +TP G S NE G + I P+ ++
Sbjct: 533 LNFSSPEDPIGYWQLAKACKGLSKACVVLETPVTGGNVSLYNETALPNGLKQPIQPTPVV 592
Query: 605 SAMGIVPDIGRVPGSDFKKEGSAIYLVG---------KPQFSFGGSVFAE-LFGIPSGES 654
+G++ DI +K +G IYL+G S + + E ++G+ +G
Sbjct: 593 GMIGLIQDINSATRQGWKDQGDQIYLLGTSIDPSILNNQNISLAATSYLENIYGLKTGRP 652
Query: 655 AAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELK-EDFH 712
+ ++ +L+ L +I L+ S HD+S+GGL L E C+ SG+G E +
Sbjct: 653 PLIDLEFEKLVQLF--LRESIANNLIKSAHDISDGGLVIGLAESCISSGLGIECNLPEID 710
Query: 713 TRLGASKIASLFGETTGCLLVEIKEEN 739
RL LF E +LV + N
Sbjct: 711 NRLD----KLLFAEGGSRVLVSVSPNN 733
>gi|71083828|ref|YP_266548.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Candidatus Pelagibacter ubique HTCC1062]
gi|91763136|ref|ZP_01265100.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Candidatus Pelagibacter ubique HTCC1002]
gi|110831819|sp|Q4FLJ4|PURL_PELUB Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|71062941|gb|AAZ21944.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Candidatus Pelagibacter ubique HTCC1062]
gi|91717549|gb|EAS84200.1| Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
[Candidatus Pelagibacter ubique HTCC1002]
Length = 730
Score = 277 bits (708), Expect = 2e-72, Method: Composition-based stats.
Identities = 214/731 (29%), Positives = 347/731 (47%), Gaps = 75/731 (10%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
KR E + W+EHC +K+ + + K K
Sbjct: 26 KRVPNITELGIFSAMWNEHCSYKSSRFHL------------------------KNLPTKG 61
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+ I P +NAG+I+ + + FK E+HNHPS IEP+ GA TGVGG++RDV
Sbjct: 62 KNVIQGPG------ENAGVIDIGDDDAIVFKIESHNHPSFIEPYQGAATGVGGIMRDVFT 115
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP A + + FG P K ++ GV+ G+ YGN MG+PT+ G +
Sbjct: 116 MGARPIANLNSIHFGSPQHKKT---------KNLLRGVVHGIGGYGNCMGVPTIAGQTSF 166
Query: 213 HEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAS 270
E+Y N LV G + K + G +I +G KTGRDG+ GA+ +S D
Sbjct: 167 DESYNGNILVNAMTLGHVKKDKIFYSKAAGLGKPVIYVGSKTGRDGIHGASMASASFDDK 226
Query: 271 TGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCD 328
+ +VQ+G+P +K + E ++ AI D GA G +S+ EMAS LG +
Sbjct: 227 IEE-KKPTVQVGDPFTEKLLLEACLELMAGDSIIAIQDMGAAGLTSSSIEMASKGNLGIE 285
Query: 329 VDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDA 388
++L+K+P + ++P+E+ LSE+QERM+I + N K E +K+ D +++ +G+ T
Sbjct: 286 INLSKVPCREANMSPYEIMLSESQERMLIVLENGKEEMAKKIFDKWNLDFAVIGQTTKSK 345
Query: 389 VLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAP-PKDGKPFIKYPEYKEPDLNAALKAV 445
+ + F E+++ ++ L P RK K A PK K + ++K + L +
Sbjct: 346 KIELYFNEEKVADIPVNTLVENSPMYDRKWKKAKLPKRIK--VDKEQFKTLKVKNVLNKI 403
Query: 446 INHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNAL 505
+++ V SKE I + YDH V G T+ +P DA V++ T KAVA S
Sbjct: 404 LSNPNVCSKEWIWQQYDHTVMGDTIQKP--------GGDAGVVRVHGT--NKAVAASVDS 453
Query: 506 NPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARS 565
+ P + + E+ RN ++ GA P AI + G P E M +E +
Sbjct: 454 SAVYCWAHPLSGGKQIVCESWRNLISVGAKP--IAITNCLNFGSPENEENMGEFVECVQG 511
Query: 566 CYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEG 625
+ + P +SG SF N + K + I P+ I +G++ D + D K+
Sbjct: 512 LGEASAYLEFPVVSGNVSFYN-----QTKDIGIKPTPAIGGVGLIKDYQNMVTMDLKEAD 566
Query: 626 SAIYLVGKPQFSFGGSVFA-ELFGIPSGESAAVPPF-KKEAAELYKKLHSNIMKGLVLSC 683
+ + ++GK + S+FA ++ +G + F +K E KL I K + S
Sbjct: 567 NILLVIGKTEGHLDQSLFARDILNEKNGPPPEINLFNEKNNGETILKL---INKKFIKSA 623
Query: 684 HDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
HD+S GG+ AL +MC+ G GA LK+ + ++ LFGE G ++EI +++
Sbjct: 624 HDVSLGGIITALSKMCIKGKKGATLKKSNYL---INQFEYLFGEDQGRYIIEISKDDLEN 680
Query: 743 FEKEMEGASIY 753
K ++ S++
Sbjct: 681 ATKILQENSVH 691
>gi|67460924|sp|Q7VEK9|PURL_PROMA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
Length = 793
Score = 276 bits (707), Expect = 3e-72, Method: Composition-based stats.
Identities = 217/747 (29%), Positives = 340/747 (45%), Gaps = 96/747 (12%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
KR E WSEHC ++ + S++ +
Sbjct: 35 KRSPNRTELGMFGVMWSEHCCYRNSR------------------------SLLSNFPTTG 70
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+ + P +NAG+++ E ++FK E+HNHPSAIEPF GA TGVGG++RD+
Sbjct: 71 KNILVGPG------ENAGVVDLGEGQRLAFKIESHNHPSAIEPFQGAATGVGGILRDIFT 124
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP A+ + L FG DTP NV ++ GV+ G+ YGN +G+PTV G V +
Sbjct: 125 MGARPIALLNSLRFGPLDTPI-NVG--------LLEGVVSGIAHYGNCVGVPTVGGEVAF 175
Query: 213 HEAYASNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATF-SSMVMDA 269
++Y+ NPLV GI + + G +I +G TGRDG+ GA+F SS + A
Sbjct: 176 DKSYSGNPLVNAMALGIMETKEIVCSGAKGIDFPVIYVGSTTGRDGMGGASFASSELTQA 235
Query: 270 STGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGC 327
S D +VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G
Sbjct: 236 SIDD--RPAVQVGDPFLEKGLIEGCLEAFKTGYVVAAQDMGAAGLTCSCSEMAAKGGVGI 293
Query: 328 DVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGD 387
++DL +P + + + +E LSE+QERM+ V K E + ++ +G+ +
Sbjct: 294 ELDLDLVPAREKNMTAYEFLLSESQERMLFVVEPGKEELIMNKFRKWGLQAKVVGKVLEE 353
Query: 388 AVLRVRFGEKEIINLSCGFLHSGPPQRK--LKAAPPKDGKPFIKYPEYKEP--------- 436
++RV ++ ++NL L P K L PP K K+ E P
Sbjct: 354 NIVRVIHEKQIVVNLPADSLAEDTPVNKHELLEEPPGFIKDHWKWDETSLPKVSIKGVHF 413
Query: 437 -------DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIK 489
D N + +++ + SK I YD++VQ T++ P G DAA+I+
Sbjct: 414 KENNTILDWNQIILRLLDDPTIASKRWIYNQYDYQVQNNTIIAPGIG-------DAALIR 466
Query: 490 PMETEGK-----KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDN 544
E E + + +A R LDP A +A+ EA RN GA P A+ DN
Sbjct: 467 LREIENQNQNSNRGIAAVVDCPNRWVALDPERGAIAAVAEASRNISCVGAKP--LAVTDN 524
Query: 545 FCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLI 604
P P W L + + +V +TP G S NE G + I P+ ++
Sbjct: 525 LNFSSPEDPIGYWQLAKACKGLSKACVVLETPVTGGNVSLYNETALPNGLKQPIQPTPVV 584
Query: 605 SAMGIVPDIGRVPGSDFKKEGSAIYLVG---------KPQFSFGGSVFAE-LFGIPSGES 654
+G++ DI +K +G IYL+G S + + E ++G+ +G
Sbjct: 585 GMIGLIQDINSATRQGWKDQGDQIYLLGTSIDPSILNNQNISLAATSYLENIYGLKTGRP 644
Query: 655 AAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELK-EDFH 712
+ ++ +L+ L +I L+ S HD+S+GGL L E C+ SG+G E +
Sbjct: 645 PLIDLEFEKLVQLF--LRESIANNLIKSAHDISDGGLVIGLAESCISSGLGIECNLPEID 702
Query: 713 TRLGASKIASLFGETTGCLLVEIKEEN 739
RL LF E +LV + N
Sbjct: 703 NRLD----KLLFAEGGSRVLVSVSPNN 725
>gi|86750823|ref|YP_487319.1| phosphoribosylformylglycinamidine synthase II [Rhodopseudomonas
palustris HaA2]
gi|86573851|gb|ABD08408.1| phosphoribosylformylglycinamidine synthase II [Rhodopseudomonas
palustris HaA2]
Length = 736
Score = 276 bits (707), Expect = 3e-72, Method: Composition-based stats.
Identities = 233/748 (31%), Positives = 351/748 (46%), Gaps = 96/748 (12%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ ++I + G
Sbjct: 32 REPTFTELGIFSAMWNEHCSYKS--SRIHLKGLP-------------------------- 63
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
APWVL +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 64 --TKAPWVLQGPGENAGVIDIGDNQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTM 121
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P + ++SGV+ GV YGN G+PTV G +H
Sbjct: 122 GARPIACLNALSFGDPSHPKT---------RHLVSGVVAGVGGYGNSFGVPTVGGQTRFH 172
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV G+A K G I+ LG KTGRDG+ GAT +S D +
Sbjct: 173 TRYDGNILVNAMAVGLADSDKIFLAAASGVGMPIVYLGSKTGRDGMGGATMASAEFDEGS 232
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ + AI D GA G + + EM + LG D+
Sbjct: 233 EE-KRPTVQVGDPFAEKLLLEACLEIMAKDCVIAIQDMGAAGLTCSAVEMGAKGDLGVDL 291
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL +P + G+ +E+ LSE+QERM++ + +K + +++ ++ +G T
Sbjct: 292 DLDAVPTRETGMTAYEMMLSESQERMLMVLKPEKEKEAEEIFRKWGLDFAIVGYTTPTKR 351
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFI---KYPEYKEPDLNA------ 440
V+ G G + + P ++L P +P + K P ++NA
Sbjct: 352 FVVKHG---------GAVKADLPIKELGDEAPLYDRPHVPSPKLPVIHAREVNAPMPVPE 402
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
AL+ ++ + SK + YDH + G T+ RP DAAV++ +G K +A
Sbjct: 403 ALEKLLATPDLCSKRWVWEQYDHVIGGNTLQRP--------GGDAAVVRV--EDGPKGLA 452
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
++ + PR DPY A+ EA RN A G P AI DN G+P RPE M L+
Sbjct: 453 LTVDVTPRYCEADPYEGGKQAVAEAYRNITAVGGKP--LAITDNLNFGNPERPEIMGQLV 510
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ + +P +SG S NE + G+ + PS I +G++ D +
Sbjct: 511 GCLKGISEACIALDSPIVSGNVSLYNE---TSGRGILPTPS--IGGVGLLDDFTKSATLA 565
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV 680
FK EG AI L+G+ G SV+ L + E A PP +K H ++++G++
Sbjct: 566 FKAEGEAILLIGETHGWLGQSVY--LRDVCGREEGAPPPVDLAC----EKRHGDVVRGMI 619
Query: 681 -----LSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVE 734
+ HDLS+GGL AL EM +SG IGA L + + A FGE G LV
Sbjct: 620 HAGTATAVHDLSDGGLLVALAEMAISGNIGASLDAPPDSTVAH---AWWFGEDQGRYLVT 676
Query: 735 IKEENRSAFEKEME--GASIYEIGKTCG 760
+KE++ +++ G +IG T G
Sbjct: 677 VKEDDLLTVLSKLKSVGVPCTQIGTTGG 704
>gi|116074278|ref|ZP_01471540.1| phosphoribosylformylglycinamidine synthase subunit II
[Synechococcus sp. RS9916]
gi|116069583|gb|EAU75335.1| phosphoribosylformylglycinamidine synthase subunit II
[Synechococcus sp. RS9916]
Length = 774
Score = 276 bits (706), Expect = 4e-72, Method: Composition-based stats.
Identities = 222/768 (28%), Positives = 349/768 (45%), Gaps = 108/768 (14%)
Query: 26 REFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSII 85
+E + R AE WSEHC ++ + + +P
Sbjct: 28 KEIQRRLGRDPNRAELGMFGVMWSEHCCYRNSRPLL------------SGFP-------- 67
Query: 86 KTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGG 145
+ P +L +NAG+++ + + ++FK E+HNHPSA+EPF GA TGVGG
Sbjct: 68 ----------TEGPRILVGPGENAGVVDLGDGHRLAFKIESHNHPSAVEPFQGAATGVGG 117
Query: 146 VIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPT 205
++RD+ + ARP A+ + L FG + PA + ++ GV+ G+ YGN +G+PT
Sbjct: 118 ILRDIFTMGARPIALLNALRFGPLEEPAT---------RALVEGVVAGISHYGNCVGVPT 168
Query: 206 VNGGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFS 263
+ G V + +Y+ NPLV G+ G+ ++ +G TGRDG+ GA+F+
Sbjct: 169 IGGEVAFDASYSGNPLVNAMALGLMETDDIVKSGASGVGNPVVYVGSTTGRDGMGGASFA 228
Query: 264 SMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS 323
S + A++ D +VQ+G+P ++K + E ++A G A D GA G + + EMA+
Sbjct: 229 SAELSAASLD-DRPAVQVGDPFLEKGLIEACLEAFQSGDVVAAQDMGAAGLTCSCSEMAA 287
Query: 324 A--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
LG ++DL ++P + +G+ +E LSE+QERM+ V + E L + ++ +
Sbjct: 288 KGDLGIELDLDRVPAREEGMTAYEYLLSESQERMLFVVRAGREEPLMERFRRWGLQAAVV 347
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYP--------EY 433
GR + V+RV L G + + P R L P + I P +
Sbjct: 348 GRVLEEPVVRV---------LQHGAVAAEVPSRALAEDTPINHHTLIAEPPSDIQQHWTW 398
Query: 434 KEPDLNAA---------LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQD 484
+E DL A L +++ + SK + R YD +V TV+ G D
Sbjct: 399 QEGDLPVAAADHDWGNDLLKLLDDPTIASKRWVYRQYDQQVLANTVVTSGGG-------D 451
Query: 485 AAVI--KPMETEGK-----KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPE 537
AAV+ +P + +G + VA + R LDP + +A+ EA RN GA+P
Sbjct: 452 AAVVRLRPQQGDGSLNTTVRGVAATVDCPNRSVALDPERGSMAAVAEAARNLSCVGAEP- 510
Query: 538 KTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVS 597
A+ DN P W L R TP G S NE +G
Sbjct: 511 -LAVTDNLNFPSPETDRGYWQLALACRGLSEACRSLNTPVTGGNVSLYNETRGDDGVLTP 569
Query: 598 IPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKP-------QFSFGGSVFAELFGIP 650
I P+ ++ +G+V DI +V G +++ G A+ L+G + GS + G+
Sbjct: 570 IHPTPVVGMVGMVADIDKVCGLAWRQAGDAVVLLGASADQTDDDRLGLAGSSYQ---GVI 626
Query: 651 SGESAAVPPFK--KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAEL 707
G PP A + + I KGL+ S HD S+GGLA AL E L SG GAE+
Sbjct: 627 HGLLTGRPPRVDLDLEARVQATVREAIDKGLLASAHDCSDGGLAVALAESSLASGRGAEI 686
Query: 708 KEDFHTRLGASKI---ASLFGETTGCLLVEIKEENRSAFEKEMEGASI 752
RLGAS LF E ++V +K E +A++ + A +
Sbjct: 687 ------RLGASNARLERRLFAEGGARIVVSVKAECLAAWQTLLAAAQV 728
>gi|148261648|ref|YP_001235775.1| phosphoribosylformylglycinamidine synthase II [Acidiphilium cryptum
JF-5]
gi|146403329|gb|ABQ31856.1| phosphoribosylformylglycinamidine synthase II [Acidiphilium cryptum
JF-5]
Length = 727
Score = 276 bits (705), Expect = 5e-72, Method: Composition-based stats.
Identities = 206/631 (32%), Positives = 310/631 (49%), Gaps = 78/631 (12%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
APWV+ +NAG+++ E FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 64 APWVIHGPGENAGVVDIGEGRAAIFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARP 123
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A + L FG P P KR++ GV+ G+ YGN +G+PTV G ++H +Y
Sbjct: 124 VANLNALRFGDPSLPVT---------KRVVDGVVRGIGGYGNCVGVPTVGGETNFHPSYN 174
Query: 218 SNPLVYCGCAGIAPRGKHRTKPSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
NPLV GIA + + +A G+ ++ +G KTGRDG+ GAT +S A +
Sbjct: 175 GNPLVNAMTVGIADQDRIFLSAAAGIGNPVVYVGSKTGRDGIHGATMASAEFGADAEE-K 233
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAK 333
+VQ+G+P I+K + E ++ AI D GA G +S+ EMA +G ++DL
Sbjct: 234 RPTVQVGDPFIEKLLIEACLELMATDAIVAIQDMGAAGLTSSSVEMAGKGGVGIELDLDS 293
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P + G++ +E+ LSE+QERM+I + + + + + + +++ +GR T + V+
Sbjct: 294 VPQREAGMSAYEMMLSESQERMLIVLKPGREDMARAIFEKWELDFAVIGRITDSGRIVVK 353
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDL-------------NA 440
H G + ++ AP D P + P + EP A
Sbjct: 354 --------------HQGRTEADIELAPLADQAPLYERP-WVEPAKPAPLGPVESPLPPGA 398
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEG-KKAV 499
AL A+I + S+ I YD V G T+ RP DAA+++ EG ++A+
Sbjct: 399 ALLALIGCPDLASRAWIWNQYDGTVGGQTLRRPGQA-------DAAIVR---IEGSRRAL 448
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
A++ PR + DP A A+ E+ RN A GA P A+ DN G+P +P M +
Sbjct: 449 ALTTDCTPRYCVADPETGGAQAVVESWRNITATGATP--LAVTDNLNFGNPEKPAIMGQI 506
Query: 560 IEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPD------I 613
+ R P +SG S NE +EG +I P+ I +G++ D I
Sbjct: 507 VAAIRGMGEACRALDYPIVSGNVSLYNE---TEG--TAILPTPAIGGLGVIDDGAAATGI 561
Query: 614 GRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK--L 671
PG D + L+G+ G S+F L I E A PP AAE +
Sbjct: 562 ALAPGLD-------LVLIGETSGELGASLF--LREILRREDGA-PPALDLAAEKRNGDFV 611
Query: 672 HSNIMKGLVLSCHDLSEGGLAAALYEMCLSG 702
I G + +CHD+S+GGL AL EM L+G
Sbjct: 612 RRQIHAGAIAACHDVSDGGLLVALAEMALAG 642
>gi|148643402|ref|YP_001273915.1| phosphoribosylformylglycinamidine (FGAM) synthase, PurL
[Methanobrevibacter smithii ATCC 35061]
gi|148552419|gb|ABQ87547.1| phosphoribosylformylglycinamidine (FGAM) synthase, PurL
[Methanobrevibacter smithii ATCC 35061]
Length = 716
Score = 276 bits (705), Expect = 5e-72, Method: Composition-based stats.
Identities = 198/616 (32%), Positives = 313/616 (50%), Gaps = 49/616 (7%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
D+AG++ +KY ++ E+HNHPSAIEP+GGA TG+GG++RD++ + ARP A+ D L F
Sbjct: 60 DDAGLVSVTDKYALAVGMESHNHPSAIEPYGGAGTGIGGILRDIISMGARPIALLDSLRF 119
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G D K + V+EG+ DYGN++G+PTV G V + +++ +NPLV C
Sbjct: 120 GSLDDEKS---------KYLFEHVVEGISDYGNRVGVPTVAGEVEFDDSFRTNPLVNVMC 170
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
G+ + K P GD + +GG TGRDG+ G TF+S + + + +VQ+ +P
Sbjct: 171 VGLVEKDKIVRGKAPYVGDVFLLMGGTTGRDGIHGVTFASEELTSDSETEDRPAVQVADP 230
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKIPVKYQGLA 342
+K+V E ++ D+ S + D G GG + + E+ S G VDL IP++ G+
Sbjct: 231 FTKKRVLEASLEILDEINVSGVKDLGGGGLTCCISELVDESNNGARVDLRNIPLRETGMT 290
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
P+E+ LSE+QERMV + ++ Q++CD +++ +G + + + +L
Sbjct: 291 PYEIMLSESQERMVFVINPKDVKKAQEICDKHEIVSAVIGEVIDGNNMIIDDEGSSLADL 350
Query: 403 SCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRL 460
L + PP R+LK K + +P ++ +L +++ + SK+ + +
Sbjct: 351 PT-ILLADPPSLNRELKEIAEDTSKVEVDHPPVRQ-----SLLELLSSPNIASKQWVYKQ 404
Query: 461 YDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAAS 520
YDHEVQ TV++P D DAAV++ + A+A++ N L P+ A
Sbjct: 405 YDHEVQVRTVVKPGD--------DAAVLR---IDDDTAIALTTDANTIHTKLSPFDGGAG 453
Query: 521 AIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISG 580
+ EA+RN ++ GA P A++D G+P PE +W A F P ISG
Sbjct: 454 CVAEAIRNVISMGATP--YAVVDCLNFGNPETPEILWQFKRTIEGMSLVAENFNAPVISG 511
Query: 581 KDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGG 640
SF NE +EG + I P+ + +G V +I + DFK G I L+G G
Sbjct: 512 NVSFYNE---TEG--IKINPTPAVGVIG-VENIENIRTMDFKNSGDKILLIGTTYDEVTG 565
Query: 641 SVFAELFGIPSGESAAVPPFKKE-----AAELYKKLHSNIMKGLVLSCHDLSEGGLAAAL 695
S + I + E P + E + K L + K + + HD+S GGLA AL
Sbjct: 566 SEYHRT--IHNIEKGMAPRIRIEDELANGKTILKLLDEDSSKNIT-AVHDVSHGGLAVAL 622
Query: 696 YEMCLSG-IGAELKED 710
EM + G IG E+ D
Sbjct: 623 SEMVMKGNIGCEIDLD 638
>gi|14591693|ref|NP_143781.1| phosphoribosylformylglycinamidine synthase subunit II [Pyrococcus
horikoshii OT3]
gi|14916648|sp|O59621|PURL_PYRHO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|3258397|dbj|BAA31080.1| 705aa long hypothetical phosphoribosylformylglycinamidine synthase
II [Pyrococcus horikoshii OT3]
Length = 705
Score = 276 bits (705), Expect = 5e-72, Method: Composition-based stats.
Identities = 211/664 (31%), Positives = 326/664 (49%), Gaps = 59/664 (8%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
++AGII+FD+K + E+HNHPSA+EP+GGA TGVGG++RD++ + ARP A+ D + F
Sbjct: 58 EDAGIIKFDDKTWIVIGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRF 117
Query: 167 GHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGC 226
G P +N + + V++G+ DYGN++G+PTV G + E+ + LV C
Sbjct: 118 G-PLEKEKN--------RYLFEYVVKGISDYGNRIGVPTVGGETEFDESLDNYTLVNVAC 168
Query: 227 AGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEP 284
GI H G +I +G +TGRDG+ G TF+S + + + S+VQI +P
Sbjct: 169 VGIMKPEHLVHSYVTEPGLKLIIVGNRTGRDGIHGVTFASEELSENAEEEDRSAVQIPDP 228
Query: 285 IIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLA 342
+K + E ++A G A+ D G GG + A EM G + K+ ++ G+
Sbjct: 229 FTEKLLIEATLEAVYTGKVRALKDLGGGGLTCAASEMVGKRGFGAIIYADKVLLREPGMT 288
Query: 343 PWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINL 402
P E+ +SE+QERM+ AV + +E L ++ + ++E + +G + V + ++ L
Sbjct: 289 PLEVMISESQERMLFAVRPEDVEELARIFEKYELEWSVVGEVIEEPKFIVYWKGSKVAEL 348
Query: 403 SCGFLHSGP----PQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIV 458
L P P ++ K + G P I L A + V + +K I
Sbjct: 349 PIDLLTEVPTIEWPMKEYKIE-EEVGIPRIS--------LQEAFEKVWRSPNIVAKRWIW 399
Query: 459 RLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAA 518
YDHEVQG TV++P D+AV+K E G +AI+ NP L+PY A
Sbjct: 400 EQYDHEVQGRTVVKP--------GFDSAVLKINEEYG---IAITADGNPNHCYLNPYHGA 448
Query: 519 ASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFI 578
+ E VRN V+ GA P A++DN P RPE W+ E + + A F ++
Sbjct: 449 MGLVAEVVRNLVSVGAKP--LALVDNLNFASPERPEVYWSFAETVKGLADAAKAFNLAYV 506
Query: 579 SGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSF 638
SG SF NE + I P+ +++ +G V + ++P K G + LVG+ +
Sbjct: 507 SGNVSFYNEIVDK-----PIKPTPVVAGVGKV-KLSKIPKGPNK--GDVVTLVGETKREL 558
Query: 639 GGSVFAELFGIPSGESAAVP-PFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYE 697
GGS + GI G + V +++ AE +L I LV HDLS GGL AL E
Sbjct: 559 GGSELYRVLGIRKGIAPRVNLEVERKNAESILRL---INASLVSFVHDLSRGGLLVALAE 615
Query: 698 M-CLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIG 756
+ L +G E+ T + + A F E+ G LV + E E+ E + IG
Sbjct: 616 VAALFNVGMEVT--IKTDMNPVEFA--FSESHGRYLVVLPERK---LEEAREITDLKVIG 668
Query: 757 KTCG 760
+ G
Sbjct: 669 RIIG 672
>gi|32267324|ref|NP_861356.1| phosphoribosylformylglycinamidine synthase subunit II [Helicobacter
hepaticus ATCC 51449]
gi|67460925|sp|Q7VF52|PURL_HELHP Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|32263377|gb|AAP78422.1| FGAM synthase [synthetase domain] PurL [Helicobacter hepaticus ATCC
51449]
Length = 745
Score = 276 bits (705), Expect = 5e-72, Method: Composition-based stats.
Identities = 221/744 (29%), Positives = 360/744 (48%), Gaps = 77/744 (10%)
Query: 27 EFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIK 86
E K KRP E A WSEHC +K+ K ++ +P
Sbjct: 30 EILKILKRPPNLIELGIFAAMWSEHCSYKSSKKYLN------------GFP--------- 68
Query: 87 TYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGV 146
APWV+ +NAGII+ E FK E+HNHPS IEP GA TGVGG+
Sbjct: 69 ---------TKAPWVVQGPGENAGIIDIGENLCAVFKIESHNHPSFIEPHAGAATGVGGI 119
Query: 147 IRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTV 206
+RD+ + ARP A + + FG ++N G H + ++ GV+EG+ YGN MG+PT+
Sbjct: 120 MRDIFTMGARPVASLNSIRFG---DISDNGTLGKKH-RYLLRGVVEGIGSYGNCMGVPTI 175
Query: 207 NGGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSS 264
G + + Y N LV C G+ + + + G+ +I +G KTGRDGL GA SS
Sbjct: 176 GGEMSFESCYNGNILVNAFCLGLVKKDEIFYGKAEGIGNPVIYVGSKTGRDGLGGAVMSS 235
Query: 265 MVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA-- 322
+++ V S+VQ+G+P +K + E ++ Q L I D GA G +S+ EMA
Sbjct: 236 DSFSSTSKAVR-SAVQVGDPFAEKLLLEACLELFKQDLIVGIQDMGAAGLTSSSFEMAGR 294
Query: 323 SALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
S G + L K+P++ +G+ P+EL LSE+QERM+I + + + +V+ +G
Sbjct: 295 SGSGMTLYLDKVPMREEGMNPYELMLSESQERMLICAKKGCEQQVLDIFAKWEVDAAIIG 354
Query: 383 RFTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAAL 442
T ++ + + ++ + L P + P + +K L +
Sbjct: 355 EVTKSGIMELFWYGEKCAEIPIAQLSENAPMLDMPLRP-------VAVQTHKANQLKTSQ 407
Query: 443 KA------VINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGK 496
A ++ V +K + YD VQ T+ P G+ DA++I+ T
Sbjct: 408 SAQEIFITLLGSVEVANKRWVYSQYDSSVQSNTIT-----PAGS--GDASMIRIKGT--N 458
Query: 497 KAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETM 556
A+++S N R LDP A A+ + RN++ GA P AI D G P+ PE M
Sbjct: 459 SALSMSVDCNMRYCYLDPKNGAKIAVATSGRNSIVNGAKP--LAISDCLNFGSPHNPEVM 516
Query: 557 WALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRV 616
WA E+ + + V TP +SG S +N+ S+G V I P+ I ++G++ D+ +V
Sbjct: 517 WAFKEVCQGIKESCKVLNTPVVSGNVSLHNQ---SDG--VDIYPTPSIVSVGLIDDVSKV 571
Query: 617 PGSDFKKEGSAIYLVGKPQFSFGGSVFAELF-GIPSGESAAVPPFKKEAAELYKKLHSNI 675
S F+ +G+ + L+G+ + FGGS+ ++ G G+ ++ ++ A L+ +
Sbjct: 572 VSSTFQTQGNMLVLLGEIKAEFGGSLAQKILEGHIYGQIPSIDLTQEFA--LWNLMLEAS 629
Query: 676 MKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVE 734
+ ++ + D+ EGGLA L +M L +G + + HT L + LF + C++VE
Sbjct: 630 DECMLSAAKDIGEGGLAITLAKMALGNGECQPIGCNVHTHLPSQ---LLFAPSQSCIIVE 686
Query: 735 IKEENRSAFEKEMEGASI--YEIG 756
+ E+ + +++ + I EIG
Sbjct: 687 VAGEHLNTLKQKAKQHKIAFTEIG 710
>gi|68553000|ref|ZP_00592383.1| Phosphoribosylformylglycinamidine synthase II [Prosthecochloris
aestuarii DSM 271]
gi|68240141|gb|EAN22419.1| Phosphoribosylformylglycinamidine synthase II [Prosthecochloris
aestuarii DSM 271]
Length = 758
Score = 275 bits (703), Expect = 9e-72, Method: Composition-based stats.
Identities = 215/752 (28%), Positives = 346/752 (46%), Gaps = 74/752 (9%)
Query: 4 EELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDI 63
E + L+ R L+ E R I + + R T E + WSEHC +K A
Sbjct: 5 EPEVNLNLAREHGLNEDEYRTIVDVLQ---RTPTFTELGIYSVMWSEHCSYKNSIA---- 57
Query: 64 DGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFK 123
++KT ++ + S+ +NAG+++ + V+FK
Sbjct: 58 --------------------VLKTLPREG-----GRLLTSAGEENAGLVDIGDNLAVAFK 92
Query: 124 AETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHP 183
E+HNHPSA+EP+ GA TGVGG+ RD+ + ARP A + L FG P P
Sbjct: 93 IESHNHPSAVEPYQGAATGVGGIHRDIFTMGARPVAALNSLRFGSPKDP---------RV 143
Query: 184 KRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKPSA 241
+ ++ GV+ G+ DYGN G+PTV G +++ +AY NPLV G+ K T
Sbjct: 144 RYLVDGVVRGIGDYGNSFGVPTVGGEIYFEDAYTGNPLVNAMSVGLVEHHKTVSATAEGQ 203
Query: 242 GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQG 301
G+ ++ +G TGRDG+ GATF+S + ++ D SVQ+G+P +K + E ++A G
Sbjct: 204 GNPVLIVGSATGRDGIHGATFASEDLSEASED-KRPSVQVGDPFAEKLLLEATLEAIASG 262
Query: 302 LYSAITDCGAGGYSSAVGEMASA-------LGCDVDLAKIPVKYQGLAPWELWLSEAQER 354
+ + D GA G +S+ EM++ G D++L +P + ++ +E+ LSE+QER
Sbjct: 263 FVAGLQDMGAAGITSSTSEMSARGIDKHGHGGIDINLDHVPTREDAMSAYEIMLSESQER 322
Query: 355 MVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEI--INLSCGFLHSGPP 412
M++ E + + D+ +G T D +LR+R K + I + L G P
Sbjct: 323 MLLVAEKGHEEDIIDIYRKWDIHAVVIGSVTNDNMLRIRHRGKVVAEIPATSLVLGGGAP 382
Query: 413 QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLR 472
+A K P + E DL+ +++ + SK+ + + YD VQ TV
Sbjct: 383 VYIREATEKKPETPDAQIVADSELDLHETTIQLLSRPNIASKQWVYQQYDSMVQTNTV-- 440
Query: 473 PYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAA 532
DAAVI+ + K +A+ N R L+P A+ E RN +
Sbjct: 441 -----TATGTSDAAVIRIKGS--NKGLAMQTDCNARYVYLNPREGGMIAVAECARNIACS 493
Query: 533 GADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSE 592
GA P AI + G+P +PE + F TP G SF NE S
Sbjct: 494 GARP--LAITNCLNFGNPYKPEVYYQFKTSVEGMGAACRAFNTPVTGGNVSFYNE---SS 548
Query: 593 GKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSG 652
+I P+ +I +G++ +I + GS F+ G AI L+G P + GS + + G
Sbjct: 549 LTGTAIYPTPVIGMIGLLDNIDNLTGSTFQNAGDAILLLGDPNLTLDGSEYLVMQYATPG 608
Query: 653 ESAAVPPFKKEAAELYKKLHSNI-MKGLVLSCHDLSEGGLAAALYEMCL----SGIGAEL 707
++ P F E + ++L + +GL+ S HD+S+GG+ AL E + S +G +
Sbjct: 609 KT--TPTFDLELEQRLQELLIELSAEGLLSSAHDISDGGMITALAEKAIMKKESPMGFAV 666
Query: 708 KEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
+ R + + E G +L+ + EN
Sbjct: 667 NLETSQRHESFMQELFYSEAQGRVLLSLPAEN 698
>gi|92090040|ref|ZP_01274950.1| Phosphoribosylformylglycinamidine synthase II [Lactobacillus
reuteri 100-23]
gi|91803187|gb|EAS88076.1| Phosphoribosylformylglycinamidine synthase II [Lactobacillus
reuteri 100-23]
Length = 742
Score = 275 bits (703), Expect = 9e-72, Method: Composition-based stats.
Identities = 228/772 (29%), Positives = 357/772 (46%), Gaps = 88/772 (11%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTE--KRPCTDAEFETIAQTWSEHCVHKTFK 58
M EE+ E++ LD A ++ +T+ +R E + WSEHC +K K
Sbjct: 5 MTPEEI----KEKKPYLDWSLTEAEYDYIRTQLLRRLPNYTETGLFSAMWSEHCSYKKSK 60
Query: 59 AKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKY 118
S+++ + K + P + AG+++ D+
Sbjct: 61 ------------------------SVLRLFPNKNERVLQGPG------EGAGVVDIDDGQ 90
Query: 119 EVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPK 178
V FKAE+HNHP+ +EP+ GA TGVGG++RD+ + ARP A D L FG D +
Sbjct: 91 AVVFKAESHNHPTTVEPYQGAATGVGGILRDIFSMGARPIASLDSLHFGELDNSTTRMK- 149
Query: 179 GTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTK 238
++ + G+ DYGN MGIPT+ G + Y N L G+ + +
Sbjct: 150 --------VTNTVRGIGDYGNCMGIPTIAGETTFDPCYQGNILCNAMSVGLMNQKDIQQG 201
Query: 239 PSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLID 296
+A G+ ++ +G KTGRDG+ GATF+S + S+VQ+G P ++K + E +D
Sbjct: 202 RAAGIGNAVMYVGAKTGRDGIHGATFASADFN-DENMTQRSAVQVGNPFMEKLLLEACLD 260
Query: 297 --ARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQ 352
I D GA G S+ EMAS G +++L +P + G++ +E+ LSE+Q
Sbjct: 261 LIRNHPNWLVGIQDMGAAGIVSSSAEMASEGESGMELNLDLVPQREPGMSAYEIMLSESQ 320
Query: 353 ERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP 412
ERM++ V E ++K+ D D+E +GR T + +E+ ++ L
Sbjct: 321 ERMLLCVKKGHEEDVKKIFDFYDLEAVTIGRITAGHDYVLFHDGEEVCHIPVSSLTDDVL 380
Query: 413 QRKLKAAPPKDGKPFIKYPEYKEPDLNAA--LKAVINHHAVNSKEDIVRLYDHEVQGGTV 470
+ + P + + P + NAA L A++ + K + + YD +V+ TV
Sbjct: 381 EEESLEKKPTRIELAEQQPAWIPIIDNAAEVLTALLAQSTIADKSSLYQQYDSQVRTNTV 440
Query: 471 LRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAV 530
P DA V++ T K +A++ N R L P A+ EA N +
Sbjct: 441 AGP--------GSDAGVLRIRGTH--KGLAMTTDGNGRFVYLSPEVGGQIALVEAAANII 490
Query: 531 AAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLS 590
A+GA+P AI D GDP PE W L + + + F TP ISG S NE
Sbjct: 491 ASGAEP--LAITDCLNYGDPTDPEIFWELHQSVQGMADACREFNTPVISGNVSLYNE--- 545
Query: 591 SEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIP 650
+ G+ +I P+ ++ +G++ +I RV S + G +YLVGK + + GS EL +
Sbjct: 546 NNGQ--AIHPTPMVGMVGLIKNIDRVIPSFVQHPGDKVYLVGKTRDDYAGS---ELQKMM 600
Query: 651 SGE-SAAVPPFKKEAAELY-KKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS---GIGA 705
+G+ S V F Y ++L + GLV S HDLSEGGL AL E G+
Sbjct: 601 TGDISGIVKSFDLHHVHQYMQRLLMTMENGLVSSAHDLSEGGLGVALAETVFKTDLGLKI 660
Query: 706 ELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGK 757
+L + TR LF ET G +V + E + FE+ + G + IG+
Sbjct: 661 DLADQPATR--------LFSETPGRFIVTVAPEKATEFEQVL-GKDAHLIGE 703
>gi|154248011|ref|YP_001418969.1| phosphoribosylformylglycinamidine synthase II [Xanthobacter
autotrophicus Py2]
gi|154162096|gb|ABS69312.1| phosphoribosylformylglycinamidine synthase II [Xanthobacter
autotrophicus Py2]
Length = 749
Score = 275 bits (702), Expect = 1e-71, Method: Composition-based stats.
Identities = 222/753 (29%), Positives = 344/753 (45%), Gaps = 94/753 (12%)
Query: 28 FYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKT 87
F K R + E ++ W+EHC +K+ K +
Sbjct: 39 FVKLIGREPSITELGIVSAMWNEHCSYKSSKVWL-------------------------- 72
Query: 88 YIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVI 147
T +P V+ +NAG+++ V FK E+HNHPS IEP+ GA TGVGG++
Sbjct: 73 ----RTLPTKSPRVIQGPGENAGVVDIGNGLAVVFKMESHNHPSFIEPYQGAGTGVGGIL 128
Query: 148 RDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVN 207
RDV + ARP A + L FG NV +R+++GV+ G+ YGN G+PTV
Sbjct: 129 RDVFTMGARPIAALNFLRFGD----CHNVKT-----RRLLAGVVAGIGGYGNSFGVPTVG 179
Query: 208 GGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSM 265
G V +H+ Y N LV G+A + + G I+ LG KTGRDG+ GAT +S
Sbjct: 180 GSVGFHKRYNGNILVNAMAVGLARADEIFYAAATGVGRAIVYLGSKTGRDGIHGATMASA 239
Query: 266 VMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS-- 323
A + +VQ+G+P +K + E ++ G AI D GA G +S+ EM +
Sbjct: 240 EFGADAEE-KRPTVQVGDPFAEKLLLEACLEIMKAGCVVAIQDMGAAGLTSSAVEMGAKG 298
Query: 324 ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGR 383
LG +++L +P + G+ +E+ LSE+QERM++ + + K + + + ++ +GR
Sbjct: 299 GLGVELNLDAVPCRETGMTAYEMMLSESQERMLMVIADGKEDEAEAIFRKWGLDFAIVGR 358
Query: 384 FTGDAVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPF---IKYPEYKEPDLNA 440
T V+ G + + P ++L P+ +P+ + P D+
Sbjct: 359 TTDTLRFVVKHN---------GVVEADLPIKELGDQAPEYRRPYEEPLPRPVVAPEDVRT 409
Query: 441 ------ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETE 494
AL+ +I + SK + YDH + G TV RP DAAV++ +
Sbjct: 410 NASVADALERLIASPDLCSKRWVWEQYDHLIGGNTVQRP--------GGDAAVVRI--ED 459
Query: 495 GKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPE 554
G KA+A++ + PR DP+ A+ EA RN A GA P A+ DN G+P +PE
Sbjct: 460 GPKALALTTDVTPRYCEADPFEGGKQAVAEAWRNLTAVGATP--IAVTDNLNFGNPEKPE 517
Query: 555 TMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIG 614
M + + P +SG S NE + GK I P+ I +G++ D+
Sbjct: 518 IMGQFVACVKGIGAACEALDFPVVSGNVSLYNE---TNGK--GILPTPAIGGVGLIEDLH 572
Query: 615 RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPF----KKEAAELYKK 670
+ FK G + LVGK G S F L + E A PP +K + +
Sbjct: 573 KSMTLAFKAAGEPVLLVGKTTGWLGSSAF--LNTVCEREDGAPPPVDLIAEKRNGDFVRG 630
Query: 671 LHSNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTG 729
L I G+ + HD+S+GGL A+ EM ++G +G L+ G A FGE
Sbjct: 631 L---IRDGIATAVHDVSDGGLLIAIAEMAMAGRVGTSLEA---PPAGMDPYAWWFGEDQA 684
Query: 730 CLLVEIKEENRSAF--EKEMEGASIYEIGKTCG 760
++ + + + EM G + +IGKT G
Sbjct: 685 RYVITVPSGQGAEVIHKAEMAGVPMVKIGKTGG 717
Score = 63.5 bits (153), Expect = 6e-08, Method: Composition-based stats.
Identities = 69/266 (25%), Positives = 110/266 (41%), Gaps = 31/266 (11%)
Query: 134 EPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEG 193
+PF G V R++ V A P AVTD L FG+P+ P I+ +
Sbjct: 478 DPFEGGKQAVAEAWRNLTAVGATPIAVTDNLNFGNPEKP------------EIMGQFVAC 525
Query: 194 VKDYG---NKMGIPTVNGGVH-YHEAYASNPLVYCGCAGIA-PRGKHRTK----PSAGDH 244
VK G + P V+G V Y+E L G+ H++ +AG+
Sbjct: 526 VKGIGAACEALDFPVVSGNVSLYNETNGKGILPTPAIGGVGLIEDLHKSMTLAFKAAGEP 585
Query: 245 IISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYS 304
++ +G TG G + F + V + G A V + I +K+ + + G+ +
Sbjct: 586 VLLVGKTTGWLG--SSAFLNTVCEREDG--APPPVDL---IAEKRNGDFVRGLIRDGIAT 638
Query: 305 AITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKL 364
A+ D GG A+ EMA A L P G+ P+ W E Q R VI VP+ +
Sbjct: 639 AVHDVSDGGLLIAIAEMAMAGRVGTSLEAPPA---GMDPYAWWFGEDQARYVITVPSGQG 695
Query: 365 EALQKLCDANDVELTNLGRFTGDAVL 390
+ + V + +G+ GD ++
Sbjct: 696 AEVIHKAEMAGVPMVKIGKTGGDRLI 721
>gi|152990642|ref|YP_001356364.1| phosphoribosylformylglycinamidine synthase II [Nitratiruptor sp.
SB155-2]
gi|151422503|dbj|BAF70007.1| phosphoribosylformylglycinamidine synthase II [Nitratiruptor sp.
SB155-2]
Length = 735
Score = 275 bits (702), Expect = 1e-71, Method: Composition-based stats.
Identities = 223/723 (30%), Positives = 343/723 (47%), Gaps = 85/723 (11%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ K + K +P +AP
Sbjct: 33 EIGIFSAMWSEHCSYKSSKKYL------------KGFP------------------TEAP 62
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 63 WVIQGPGENAGVIDIGDGMAAVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPVA 122
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG D E+ + H + ++ GV+ G+ YGN +G+PT+ G V + E Y N
Sbjct: 123 NLNALRFG--DVKRED--EVGAHQRYLVRGVVAGIGGYGNCVGVPTIGGEVSFDECYNGN 178
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV GI + + + G+ +I +G KTGRDGL GA SS T +
Sbjct: 179 ILVNAFSLGICKKDEIFYGRAEGVGNPVIYVGSKTGRDGLGGAVMSSDSFTEETKKLR-P 237
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDVD--LAKIP 335
+VQ+G+P +K + E ++ I D GA G +S+ EMA G + L K+P
Sbjct: 238 TVQVGDPFTEKLLLEACLELFKTDYVVGIQDMGAAGLTSSSFEMAGRAGSGMKMYLDKVP 297
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
++ +G+ P+EL LSE+QERM+I E + ++ D++ +G T V+ + +
Sbjct: 298 MREEGMTPYELMLSESQERMLICAKKGTEEKVLEIFRKWDLDAEIIGEVTDTGVMELYWH 357
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEY----KEPDLNA--------ALK 443
+++ + P + P+ +P K PEY KE ++ A +
Sbjct: 358 GEKVAEV---------PVAPVSEEAPELDRP-TKRPEYLAYIKETSIDTVPHVEDQEAFE 407
Query: 444 AVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISN 503
++ V +K + YD VQ TV P G + DA+VI+ E KA+A+S+
Sbjct: 408 KLLGSLEVVNKAWVYEQYDSMVQTNTVKHP-----GTL--DASVIRV--KENGKAIAMSS 458
Query: 504 ALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA 563
NPR +DP AA+A+ A RN +GA P AI D G+P PE MW +
Sbjct: 459 KCNPRYCYIDPKGGAAAAVMAAGRNVAMSGARP--LAITDCLNYGNPENPEVMWQFAQGT 516
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
TP +SG S NE + G VS+ P+ I+ +G+ D +V S F++
Sbjct: 517 EGIKEACRALNTPVVSGNVSLYNE---TNG--VSVYPTPTIAMVGLNDDANKVVPSYFQE 571
Query: 624 EGSAIYLVGKPQFSFGGSVF-AELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLS 682
+Y++G + FGGS++ ELFG +GE + ++KE L+ + +GL+ +
Sbjct: 572 TNDVVYIIGDTEKEFGGSLYLKELFGKVAGELPKI-DYEKE-LRLWNFVIEANNRGLLKA 629
Query: 683 CHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
D+ GG+A AL +M G + F +F ET LVEI +N A
Sbjct: 630 AKDVGVGGIAIALAKMAALG-----NKGFLGNFCFEDSREIFSETFSRALVEIDPKNMHA 684
Query: 743 FEK 745
E+
Sbjct: 685 LEE 687
>gi|85715184|ref|ZP_01046168.1| phosphoribosylformylglycinamidine synthase subunit II [Nitrobacter
sp. Nb-311A]
gi|85698099|gb|EAQ35972.1| phosphoribosylformylglycinamidine synthase subunit II [Nitrobacter
sp. Nb-311A]
Length = 736
Score = 274 bits (701), Expect = 2e-71, Method: Composition-based stats.
Identities = 220/690 (31%), Positives = 329/690 (47%), Gaps = 91/690 (13%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ ++I + G
Sbjct: 32 RTPTFTELGIFSAMWNEHCSYKS--SRIHLRGLP-------------------------- 63
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
APWV+ +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 64 --TKAPWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTM 121
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P + ++SGV+ GV YGN G+PTV G V +H
Sbjct: 122 GARPIACLNALSFGDPSHP---------RTRHLVSGVVAGVGGYGNSFGVPTVGGQVRFH 172
Query: 214 EAYASNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV G+A K ++G + I+ LG KTGRDG+ GAT +S D +
Sbjct: 173 TRYDGNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGATMASAEFDDDS 232
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ +G AI D GA G + + EM + LG D+
Sbjct: 233 EE-KRPTVQVGDPFAEKLLLEACLEIMAKGCVVAIQDMGAAGLTCSAVEMGAKGDLGVDL 291
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL +P + QG++ +E+ LSE+QERM++ + +K + + + ++ +G T
Sbjct: 292 DLDSVPTREQGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAIVGTTTPSRR 351
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYK-------EPDLNA-- 440
VR G + +L P ++L++ P +P + P+ P L
Sbjct: 352 FVVRHGGDVMADL---------PIKELESEAPLYDRPHVPSPQLPVVQARDVAPPLPVVD 402
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
AL+ +I + SK + YDH + G TV RP DAAV++ EG K +A
Sbjct: 403 ALERLIATPELCSKRWVWEQYDHVIGGNTVQRP--------GGDAAVVRV--EEGPKGLA 452
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
++ + PR DP+ A+ EA RN A G P AI DN G+P RPE M +
Sbjct: 453 LTVDVTPRYCEADPFEGGKQAVAEAWRNITAVGGRP--LAITDNLNFGNPERPENMGQFV 510
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ P +SG S NE + G+ + PS I +G++ D +
Sbjct: 511 GCLKGIAAACAALDFPVVSGNVSLYNE---TNGRGILPTPS--IGGVGLLDDFTKSASLA 565
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV 680
FK EG I L+G Q G SV+ L I E A PP A +K + ++++G++
Sbjct: 566 FKAEGHPILLIGDTQGWLGQSVY--LRDICGREEGAPPPVDLAA----EKRNGDVVRGMI 619
Query: 681 -----LSCHDLSEGGLAAALYEMCL-SGIG 704
+ HD+S+GGL AL EM + SGIG
Sbjct: 620 HAGTATAVHDVSDGGLLVALAEMAMASGIG 649
>gi|114797329|ref|YP_760643.1| phosphoribosylformylglycinamidine synthase II [Hyphomonas neptunium
ATCC 15444]
gi|114737503|gb|ABI75628.1| phosphoribosylformylglycinamidine synthase II [Hyphomonas neptunium
ATCC 15444]
Length = 753
Score = 274 bits (701), Expect = 2e-71, Method: Composition-based stats.
Identities = 215/665 (32%), Positives = 332/665 (49%), Gaps = 64/665 (9%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
P V+ +NAG+I+ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 73 GPRVIQGPGENAGVIDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARP 132
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A+ + L FG P P +++++GV+ G+ YGN +G+PTV G + E Y
Sbjct: 133 VALVNALRFGDPSHPKT---------RQLVAGVVAGIGGYGNCVGVPTVAGETQFDEGYN 183
Query: 218 SNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
N LV G+A + K + G I+ +G KTGRDG+ GAT +S D
Sbjct: 184 GNILVNAMAVGLADQDKIFYARGALPGLQILYVGSKTGRDGIHGATMASAEFTEGEED-N 242
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDLAK 333
+VQ+G+P +K + E ++ +I D GA G +S+ EMA +G ++DL K
Sbjct: 243 RPTVQVGDPFTEKLLIEACLELMATDAIQSIQDMGAAGLTSSSVEMADKGGVGIEMDLDK 302
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFT--GDAVLR 391
+P + G+ +E+ LSE+QERM++ + K +K+ D D++ +G T G VL+
Sbjct: 303 VPQRETGMTAYEIMLSESQERMLMILKPGKEAVAKKIFDKWDLDAEVIGVTTDSGRLVLK 362
Query: 392 VRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAA---------- 441
+FGE + C P L P +P+ + P K PD + +
Sbjct: 363 -QFGE-----VVCDI-----PVAPLGEDAPNYDRPWTEPP--KRPDFDISKHPAPANYAE 409
Query: 442 -LKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
L +++ + SK + YD V T+ G DAA+++ T KA+A
Sbjct: 410 VLTKLMSTPDMASKRWVWEQYDRHVMNDTIDSSQSG------GDAAIVRVHGT--NKALA 461
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
I + NP DPY A+ EA RN A GA P AI DN G+P +P TM ++
Sbjct: 462 ICSDCNPHYVAADPYEGGKQAVAEAYRNLSAVGATP--IAITDNLNFGNPEKPATMGYIV 519
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ V P +SG S NE ++GK +IPP+ ++ +G++ D+ ++
Sbjct: 520 KAIEGMAEACRVLNFPVVSGNVSLYNE---TDGK--AIPPTPVVGGVGLIDDLSKIATLK 574
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFA-ELFGIPSGESAAVPPFKKE----AAELYKKLHSNI 675
+ G A+ ++G+ FG S++A + G+ + PP E + + ++L I
Sbjct: 575 GAQPGDALIIIGENAADFGASLYARKWLGLKGDDLGPPPPVDLEDEIQTSAIVREL---I 631
Query: 676 MKGLVLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGA-SKIASLFGETTGCLLVE 734
KGLV + HD+S+GGLA A EM L+G + + RLG+ S +A LF ET G LV
Sbjct: 632 AKGLVHAVHDISDGGLAVAAAEMALAGNVGIMLDAQADRLGSLSPLAYLFSETQGRYLVA 691
Query: 735 IKEEN 739
K E+
Sbjct: 692 AKNED 696
>gi|148238339|ref|YP_001223726.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Synechococcus sp. WH 7803]
gi|147846878|emb|CAK22429.1| Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase
domain [Synechococcus sp. WH 7803]
Length = 765
Score = 274 bits (701), Expect = 2e-71, Method: Composition-based stats.
Identities = 220/738 (29%), Positives = 346/738 (46%), Gaps = 92/738 (12%)
Query: 39 AEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDA 98
AE WSEHC ++ + + + +P D
Sbjct: 29 AELGMFGVMWSEHCCYRNSRPLL------------RGFP------------------TDG 58
Query: 99 PWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPF 158
P +L +NAG+++ E + ++FK E+HNHPSA+EPF GA TGVGG++RD+ + ARP
Sbjct: 59 PRILVGPGENAGVVDLGEGHRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPI 118
Query: 159 AVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYAS 218
A+ + L FG D PA + ++ GV+ G+ YGN +G+PTV G V + AY
Sbjct: 119 ALLNALRFGPLDEPAT---------QGLVEGVVAGISHYGNCVGVPTVGGEVAFDPAYRG 169
Query: 219 NPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAG 276
NPLV G+ G+ ++ +G TGRDG+ GA+F+S + A + D
Sbjct: 170 NPLVNAMALGLMETDDIVKSGASGVGNPVVYVGSTTGRDGMGGASFASAELSADSLD-DR 228
Query: 277 SSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKI 334
+VQ+G+P ++K + E ++A G A D GA G + + EMA+ +G ++DL ++
Sbjct: 229 PAVQVGDPFLEKGLIEACLEAFQSGDVVAAQDMGAAGLTCSCSEMAAKGNVGVELDLDRV 288
Query: 335 PVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRF 394
P + QG+ +E LSE+QERM+ V + EAL + ++ +G+ + V+RV
Sbjct: 289 PAREQGMTAYEFLLSESQERMLFVVQAGREEALMQRFRRWGLQAAVVGQVLEEPVVRVLQ 348
Query: 395 GEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP------DLNAALKAVI 446
+ L P Q L + PP+D + ++ E P D A L A++
Sbjct: 349 HGSVAAEVPARALAEDTPINQHTLISEPPEDIQEHWRWSETDLPSVSRDHDWGADLLALL 408
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEG-------KKAV 499
+ + SK + R YD +V TV+ P G DAAV++ +G + V
Sbjct: 409 DDPTIASKRWVYRQYDQQVLANTVV-----PAGGA--DAAVVRLRPQQGDASLRGANRGV 461
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
A + R LDP A +A+ EA RN GA P A+ DN P P+ W L
Sbjct: 462 AATVDCPNRWVALDPERGAMAAVAEAARNLSCVGAVP--VAVTDNLNFPSPETPKGYWQL 519
Query: 560 IEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGS 619
R V TP G S NE + +G I P+ ++ +G+V D+GRV G
Sbjct: 520 AMACRGLSEGCRVLGTPVTGGNVSLYNETRADDGSLQPIHPTPVVGMVGLVEDLGRVGGL 579
Query: 620 DFKKEGSAIYLVG-------KPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLH 672
+++ G A+ L+G + GS + G+ G PP + +L +++
Sbjct: 580 AWRQAGDAVVLLGVSSDERQDDRVGLAGSSYQ---GVIHGLLTGRPP--RVDLDLEQRVQ 634
Query: 673 SNIM----KGLVLSCHDLSEGGLAAALYEMCL-SGIGAE--LKEDFHTRLGASKIASLFG 725
+ + +GL+ S HD S+GGLA AL E + SG+G + L D G + LF
Sbjct: 635 ALVRQAWEQGLLASAHDSSDGGLAVALAECSIASGLGVDGALPGD-----GVAPERRLFA 689
Query: 726 ETTGCLLVEIKEENRSAF 743
E ++V ++ E A+
Sbjct: 690 EGGARIVVSVRAECMDAW 707
>gi|78776746|ref|YP_393061.1| Phosphoribosylformylglycinamidine synthase II [Thiomicrospira
denitrificans ATCC 33889]
gi|110831840|sp|Q30T55|PURL_THIDN Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|78497286|gb|ABB43826.1| Phosphoribosylformylglycinamidine synthase II [Thiomicrospira
denitrificans ATCC 33889]
Length = 737
Score = 273 bits (699), Expect = 2e-71, Method: Composition-based stats.
Identities = 213/713 (29%), Positives = 339/713 (47%), Gaps = 67/713 (9%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ +K+ + G +P AP
Sbjct: 37 EIGIFSAMWSEHCSYKS--SKVHLSG----------FP------------------TKAP 66
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ Y FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 67 WVIQGPGENAGVIDIGGGYAAVFKMESHNHPSFIEPYQGAATGVGGIMRDVFTMGARPIA 126
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ L FG D +N K + H + ++ GV+ G+ YGN MG+PT+ G + E Y N
Sbjct: 127 NLNALRFG--DVLKDN--KTSAHQRYLVRGVVAGIGGYGNCMGVPTIGGETSFDECYNGN 182
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV G+A + + G+ +I +G KTGRDGL GA SS + +
Sbjct: 183 ILVNAFTLGLAKSDEIFYGRADGIGNPVIYVGAKTGRDGLGGAVMSSDSFTEESKSLR-P 241
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMA--SALGCDVDLAKIP 335
+VQ+G+P +K + E ++ I D GA G +S+ EMA S G + L ++P
Sbjct: 242 TVQVGDPFTEKLLLEACLELFKTDHVVGIQDMGAAGLTSSSFEMAGRSGSGMIMHLDRVP 301
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
+ +G+ P++ LSE+QERM++ + K+ + D++ +G T + + +
Sbjct: 302 AREEGMTPYDFMLSESQERMLLCAKKGSEAEIIKIFEKWDLDAAVIGEVTATGNMELFWH 361
Query: 396 EKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNS 453
++ + + P R + D + ++ A + + V
Sbjct: 362 GDKVAEVPVNPVSEEAPVLNRPMSRPAYLDKIASVTIDDFARVPNQEAFERLTKSMEVVD 421
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
K I YD VQ T+ +G + DA+V++ E KA+A+S N R +D
Sbjct: 422 KSWIYTQYDSMVQTNTI------KKGGM-LDASVVRV--KENGKALAMSADCNVRYCYID 472
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVF 573
P AA+A+ E+ RN +GA P AI D G+P PE MW +
Sbjct: 473 PKGGAAAAVIESGRNVAMSGARP--LAITDCLNFGNPENPEVMWQFGQSCLGIKEACSAL 530
Query: 574 KTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGK 633
TP I G S NE + G VS+ P+ I+ +G+ D +V S F+ EG+ +YLVG+
Sbjct: 531 TTPVIGGNVSLYNE---TNG--VSVFPTPSIATVGVNDDQNKVLMSSFQGEGNTLYLVGE 585
Query: 634 PQFSFGGSVF-AELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLA 692
FGGS++ E+ G+ +G + ++KE + +N KG++ D S GG+A
Sbjct: 586 SNSEFGGSLYMKEICGVVAGVLPEI-DYEKELTLWDLVIEAN-KKGILECAKDASSGGVA 643
Query: 693 AALYEM-CLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFE 744
AL +M +SG+G R+ + +F E+ ++E+K+EN ++FE
Sbjct: 644 IALAKMAAVSGLGCS------ARMLVNDERDIFAESMSRAIIEVKQENSASFE 690
>gi|87123346|ref|ZP_01079197.1| Phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
RS9917]
gi|86169066|gb|EAQ70322.1| Phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
RS9917]
Length = 764
Score = 273 bits (699), Expect = 3e-71, Method: Composition-based stats.
Identities = 217/754 (28%), Positives = 354/754 (46%), Gaps = 84/754 (11%)
Query: 26 REFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSII 85
RE + R AE WSEHC ++ + + + +P
Sbjct: 16 REIQRRLGRDPNRAELGMFGVMWSEHCCYRNSRPLL------------RGFP-------- 55
Query: 86 KTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGG 145
+ P +L +NAG+++ + + ++FK E+HNHPSA+EPF GA TGVGG
Sbjct: 56 ----------TEGPRILVGPGENAGVVDLGDGHRLAFKIESHNHPSAVEPFQGAATGVGG 105
Query: 146 VIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPT 205
++RD+ + ARP A+ + L FG + P+ + ++ GV+ G+ YGN +G+PT
Sbjct: 106 ILRDIFTMGARPIALLNALRFGPMEEPSN---------RGLLEGVVAGIAHYGNCVGVPT 156
Query: 206 VNGGVHYHEAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFS 263
V G V + +Y+ NPLV G+ + G+ ++ +G TGRDG+ GA+F+
Sbjct: 157 VGGEVAFDPSYSGNPLVNAMALGLMETEEIVKSGASGVGNPVVYVGSTTGRDGMGGASFA 216
Query: 264 SMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS 323
S + S+ D +VQ+G+P ++K + E ++A G A D GA G + + EMA+
Sbjct: 217 SAELSGSSLD-DRPAVQVGDPFLEKGLIEACLEAFQSGDVIAAQDMGAAGLTCSCAEMAA 275
Query: 324 A--LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNL 381
+G ++DL ++P + +G+ +E LSE+QERM+ V + + L + ++ +
Sbjct: 276 KGHVGVELDLDRVPAREEGMTAYEFLLSESQERMLFVVRAGREQPLMERFRRWGLQAAVV 335
Query: 382 GRFTGDAVLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPEYKEP--- 436
G+ + V+RV + L P L A PP D + ++ + + P
Sbjct: 336 GQVLAEPVVRVLQHGAVAAEIPARALAEDTPINSHSLLADPPLDIQQHWQWQDSELPGAA 395
Query: 437 ---DLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPM 491
D A L A+++ + SK + R YD +V TV++ DAAV+ +P
Sbjct: 396 LEHDWGADLLALLDDPTIASKRWVYRQYDQQVLANTVIQAGGA-------DAAVVRLRPQ 448
Query: 492 ETEG-----KKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFC 546
+ +G ++AVA + R LDP A +A+ EA RN GADP A+ DN
Sbjct: 449 QGDGSLQGTERAVAATVDCPNRWVALDPERGAMAAVAEAARNLSCVGADP--LAVTDNLN 506
Query: 547 LGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISA 606
P+ W L R TP G S NE S +G V I P+ ++
Sbjct: 507 FPSPDTDRGYWQLAMACRGLAEACRRLNTPVTGGNVSLYNETRSDDGASVPIHPTPVVGM 566
Query: 607 MGIVPDIGRVPGSDFKKEGSAIYLVGKP-------QFSFGGSVFAELFGIPSGESAAVPP 659
+G+V I +V G +++ + L+G P + GS + G+ G PP
Sbjct: 567 VGVVESIAKVIGLGWRQPADPVVLLGVPIDGQADDRLGLAGSAYQ---GVIHGALTGRPP 623
Query: 660 FKKEAAELYKK--LHSNIMKGLVLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLG 716
E+ + + + I +GL+ S HD S+GGLA AL E CL+ G+GA + D + G
Sbjct: 624 RPDLDLEVRVQALVRAAIGQGLLASAHDCSDGGLAVALAESCLAVGLGAAI--DLGSS-G 680
Query: 717 ASKIASLFGETTGCLLVEIKEENRSAFEKEMEGA 750
+ LF E ++V +K E A++ + GA
Sbjct: 681 SRPEQLLFAEGGARIIVSVKAEALEAWQALLAGA 714
>gi|103487678|ref|YP_617239.1| phosphoribosylformylglycinamidine synthase II [Sphingopyxis
alaskensis RB2256]
gi|98977755|gb|ABF53906.1| phosphoribosylformylglycinamidine synthase II [Sphingopyxis
alaskensis RB2256]
Length = 747
Score = 273 bits (699), Expect = 3e-71, Method: Composition-based stats.
Identities = 219/714 (30%), Positives = 335/714 (46%), Gaps = 87/714 (12%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ + + K P +AP
Sbjct: 38 ELGIFSVMWSEHCSYKSSRIHL------------KKLP------------------TEAP 67
Query: 100 WVLSSFVDNAGIIEFDE-----KYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVS 154
WV+ +NAG+I+ E K FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 68 WVICGPGENAGVIDIGEGPDGKKLAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMG 127
Query: 155 ARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHE 214
ARP A + L FG PD P + +I+GV+ G+ YGN +G+PTV G V++H
Sbjct: 128 ARPVANLNALRFGRPDHPKM---------RHLIAGVVHGIGGYGNCVGVPTVGGEVNFHA 178
Query: 215 AYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTG 272
AY N LV G+A + + + G+ I+ +G KTGRDG+ GAT +S A G
Sbjct: 179 AYDGNILVNAMTVGVAEQDRIFYSAASGVGNPIVYVGSKTGRDGIHGATMAS----ADFG 234
Query: 273 DVAGS---SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGC 327
+ A +VQ+G+P +K + E ++ AI D GA G +S+ EMAS +G
Sbjct: 235 EDAEEKRPTVQVGDPFTEKLLIEACLELMASDAIVAIQDMGAAGLTSSSVEMASKGGVGI 294
Query: 328 DVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGD 387
+ + +P + G+ +E+ LSE+QERM++ + K E + + +++ +G T
Sbjct: 295 HLRMDDVPQRETGMTAYEMMLSESQERMLMVLKPGKEEFAKAIFHKWELDFAVIGTVTDT 354
Query: 388 AVLRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVIN 447
+ + + + ++ L P P PE K D+ A LKA++
Sbjct: 355 GRMVLEHHGQIVCDIPLAPLADDAPLYDRPHVPTPKQPELSDVPETK--DVAADLKALMG 412
Query: 448 HHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNP 507
+ S+ I YD +V TV DAA+++ T +A+A+S P
Sbjct: 413 TPDIASRRWIWEQYDSQVGADTV---------QTGGDAALVRIHGT--NRALAMSTDCTP 461
Query: 508 RQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI----EMA 563
R DP A+ E RN A GA P AI + +P RPE M ++ MA
Sbjct: 462 RYCYADPVEGGKQAVAETWRNISAVGATP--LAITNCLNFANPQRPEIMGQIVGCLDGMA 519
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
++C P +SG S NE ++ G +I P+ I +G++ D+G+ G FK+
Sbjct: 520 QACR----ALDYPIVSGNVSLYNESKATGGGS-AILPTPAIGGVGVIEDLGKAVGIGFKR 574
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK-LHSNIMKGLVLS 682
G + VG+ G S++ L I E PP +A + + +I G + +
Sbjct: 575 TGDIVLAVGERMGHLGQSIW--LREIHGREEGPPPPVDLKAEKRTGDFIRQSINAGWITA 632
Query: 683 CHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEI 735
CHD+S+GG+A AL EM L S IG + E+ G ++ S FGE G LV +
Sbjct: 633 CHDVSDGGVAVALAEMALKSNIGVLVSEE--QPFGVAE--SFFGEDQGLYLVTV 682
>gi|90423102|ref|YP_531472.1| phosphoribosylformylglycinamidine synthase II [Rhodopseudomonas
palustris BisB18]
gi|90105116|gb|ABD87153.1| phosphoribosylformylglycinamidine synthase II [Rhodopseudomonas
palustris BisB18]
Length = 736
Score = 273 bits (698), Expect = 3e-71, Method: Composition-based stats.
Identities = 225/689 (32%), Positives = 334/689 (48%), Gaps = 76/689 (11%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
APWVL +NAG+I+ + + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 66 APWVLQGPGENAGVIDIGDNEAIVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARP 125
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A + L FG P+ P + ++SGV+ GV YGN G+PTV G V + Y
Sbjct: 126 IACLNALSFGAPEHPKT---------RHLVSGVVAGVGGYGNSFGVPTVGGQVRFDTRYD 176
Query: 218 SNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
N LV G+A K G I+ LG KTGRDG+ GA+ +S V D + +
Sbjct: 177 GNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGIHGASMASAVFDDDSAE-K 235
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAK 333
+VQ+G+P +K + E ++ AI D GA G +S+ EM + LG D+DL K
Sbjct: 236 RPTVQVGDPFAEKLLLEACLEIMAADCVIAIQDMGAAGLTSSAVEMGAKGNLGVDLDLDK 295
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P + G+ +E+ LSE+QERM++ + +K + + ++ +G T V+
Sbjct: 296 VPTREPGMTAYEMMLSESQERMLMVLKPEKEREAEAIFKKWGLDFAIVGHTTPTLRFVVK 355
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNA-----------AL 442
G G + + P ++L P +P ++ P K P ++A AL
Sbjct: 356 HG---------GEVKADLPIKELGDEAPLYDRPHVETP--KLPIIHARDIKPPIGVVEAL 404
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
+ +I + S+ + YDH + G TV RP DAAV++ +G K +A++
Sbjct: 405 EKLIGSPELCSRRWVWEQYDHVIGGNTVQRP--------GGDAAVVRI--KDGPKGLALT 454
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
+ PR DPY A+ EA RN A G P AI DN G+P RPE M L+
Sbjct: 455 VDVTPRYCEADPYEGGKQAVAEAYRNITAVGGKP--LAITDNLNFGNPERPEIMGQLVGC 512
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
+ + + P +SG S NE + G+ + PS I +G++ D + FK
Sbjct: 513 LKGIAEACVALEAPIVSGNVSLYNE---TNGRGILPTPS--IGGVGLLDDFTKSATLAFK 567
Query: 623 KEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLS 682
G AI L+G+ + G SV+ L I E A PP +A +K + +++G++ S
Sbjct: 568 AAGEAILLIGETRGWLGQSVY--LRDICGREEGAPPPVNLDA----EKRNGTVVRGMIHS 621
Query: 683 -----CHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKI---ASLFGETTGCLLV 733
HDLS+GGL AL EM ++G IGA L G I A FGE LV
Sbjct: 622 GTATAVHDLSDGGLLIALAEMAIAGHIGAALDA------GPEAIVPHAWWFGEDQARYLV 675
Query: 734 EIKEENRSAFEKEME--GASIYEIGKTCG 760
+ + +++ G +IGKT G
Sbjct: 676 TVPADELLGVLTKLKAVGVPCLQIGKTAG 704
>gi|92117186|ref|YP_576915.1| phosphoribosylformylglycinamidine synthase II [Nitrobacter
hamburgensis X14]
gi|91800080|gb|ABE62455.1| phosphoribosylformylglycinamidine synthase II [Nitrobacter
hamburgensis X14]
Length = 744
Score = 273 bits (698), Expect = 4e-71, Method: Composition-based stats.
Identities = 207/631 (32%), Positives = 316/631 (50%), Gaps = 65/631 (10%)
Query: 98 APWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARP 157
APWV+ +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV + ARP
Sbjct: 66 APWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARP 125
Query: 158 FAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYA 217
A + L FG P P + ++ GV+ GV YGN G+PTV G V +H Y
Sbjct: 126 IACLNALSFGDPSHPKT---------RHLVGGVVAGVGGYGNSFGVPTVGGQVRFHTRYD 176
Query: 218 SNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATFSSMVMDASTGDVA 275
N LV G+A K ++G + I+ LG KTGRDG+ GAT +S D + +
Sbjct: 177 GNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGATMASAEFDDDSAE-K 235
Query: 276 GSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAK 333
+VQ+G+P +K + E ++ + AI D GA G + + EM + LG D+DL
Sbjct: 236 RPTVQVGDPFAEKLLLEACLEIMETDCVIAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDS 295
Query: 334 IPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVR 393
+P + QG++ +E+ LSE+QERM++ + +K + + + ++ +G T V+
Sbjct: 296 VPTREQGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAIVGYTTPSQRFVVK 355
Query: 394 FGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNA-----------AL 442
G +++L P ++L++ P +P + P+ P ++A AL
Sbjct: 356 HGGDVMVDL---------PIKELESEAPLYDRPHVPSPQL--PVVHARDVAPRLPVADAL 404
Query: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
+ +I + SK + YDH + G TV RP DAAV++ +G K +A++
Sbjct: 405 EKLIATPELCSKRWVWEQYDHVIGGNTVQRP--------GGDAAVVRV--EDGPKGLALT 454
Query: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEM 562
+ PR DP+ A+ EA RN A G P AI DN G+P RPE M +
Sbjct: 455 VDVTPRYCEADPFEGGKQAVAEAWRNITAVGGRP--LAITDNLNFGNPERPEIMGQFVGC 512
Query: 563 ARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFK 622
+ P +SG S NE + G+ + PS I +G++ D + FK
Sbjct: 513 LKGIAAACTALDFPVVSGNVSLYNE---TNGRGILPTPS--IGGVGLLDDFTQSASLAFK 567
Query: 623 KEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGL--- 679
EG I L+G+ Q G SV+ L + E A PP A +K + ++++G+
Sbjct: 568 AEGECILLIGETQGWLGQSVY--LRDVCGREEGAPPPVDLAA----EKRNGDVVRGMIHA 621
Query: 680 --VLSCHDLSEGGLAAALYEMCLS-GIGAEL 707
V + HD+S+GGL AL EM ++ GIGA L
Sbjct: 622 GTVTAVHDISDGGLLVALAEMAMAGGIGAAL 652
>gi|86606032|ref|YP_474795.1| phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
JA-3-3Ab]
gi|110831829|sp|Q2JQL7|PURL_SYNJA Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|86554574|gb|ABC99532.1| phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
JA-3-3Ab]
Length = 766
Score = 273 bits (698), Expect = 4e-71, Method: Composition-based stats.
Identities = 238/771 (30%), Positives = 352/771 (45%), Gaps = 114/771 (14%)
Query: 21 EMRAIREFYKTEKRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLC 80
E R I++ + P A F + WSEHC +K + + T T E+ PG
Sbjct: 19 EYRQIQQQLGRDPNPTELAMFGVM---WSEHCCYKNSRPLLKHFPT--TGERVVVGPG-- 71
Query: 81 VNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGAN 140
+NAG+++ + ++FK E+HNHPSA+EPF GA
Sbjct: 72 --------------------------ENAGVVDLGDGDWLAFKIESHNHPSAVEPFQGAA 105
Query: 141 TGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK 200
TGVGG++RD+ + ARP A+ + L FG P T N +R+++ V+EG+ YGN
Sbjct: 106 TGVGGILRDIFTLGARPIALLNSLRFG-PLTDPRN--------RRLMARVVEGIAHYGNC 156
Query: 201 MGIPTVNGGVHYHEAYASNPLVYCGCAGI--APRGKHRTKPSAGDHIISLGGKTGRDGLR 258
+G+PTV G V Y+ NPLV G+ P G+ I+ +G TGRDG+R
Sbjct: 157 VGVPTVGGEVAVDPCYSGNPLVNVMALGLLETPAVVKSAARGVGNPILYVGATTGRDGIR 216
Query: 259 GATFSSMVM--DASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSS 316
GA+F+S + DA A VQ+G+P + K + E ++A A D GA G +
Sbjct: 217 GASFASAELKEDAQQDRPA---VQVGDPFLGKCLIEACLEAFATVAVVAAQDMGAAGITC 273
Query: 317 AVGEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAN 374
+ EMA+ +G DL ++P + G+A WE LSE+QERM++ V + + ++
Sbjct: 274 STAEMAAKGGVGIRFDLDRVPARESGMAAWEYLLSESQERMLLVVQKGREAEVMEIFHRW 333
Query: 375 DVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP--QRKLKAAPPKDGKPFIKYPE 432
++ + G + ++ + ++ + L P R L PP+ + ++
Sbjct: 334 GLQASVAGEVIAEPLVEIWHQGSCVVRVPARALAEDTPVYVRPLLPEPPEYVQAAWQWDP 393
Query: 433 YKEPDLN--------------AALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPE 478
P + L ++ + SK I R YDH+VQ TVL P G
Sbjct: 394 STLPPCDRQGIHLPQKTLAWEQVLLQLLASPTLASKAWIYRQYDHQVQNNTVLWPGQG-- 451
Query: 479 GNVPQDAAVIK-----------PMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVR 527
DAAVI+ P +KA+A + N R LDPY A +A+ EA R
Sbjct: 452 -----DAAVIRIRSQKFGVGEVPPLQAARKAIAATLDGNGRWVYLDPYEGAKAAVAEAAR 506
Query: 528 NAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNE 587
N GADP AI DN G P P W L R TP G S NE
Sbjct: 507 NLSCVGADP--LAITDNLNFGSPENPVVYWQLALACRGIAEACRALGTPVTGGNVSLYNE 564
Query: 588 YLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQF-SFGGSVF-AE 645
S +I P+ +I +G++PD+ + G +++EG +YL+G S GGS + A
Sbjct: 565 KGSQ-----AIYPTPVIGMVGLIPDLKFICGQGWQQEGDLVYLLGSQAVTSLGGSEYLAA 619
Query: 646 LFGIPSGESAAVPPFKKEAAELYKKLHS----NIMKGLVLSCHDLSEGGLAAALYEMCLS 701
++ +G A V EL K++ I +G V S HD SEGGLA AL E CLS
Sbjct: 620 IYNKVTGRPAPVD------LELEKRVQGACRHGIRQGWVRSAHDCSEGGLAVALAEACLS 673
Query: 702 -GIGAELKEDFHTRLGASKI---ASLFGETTGCLLVEIKEENRSAFEKEME 748
G GA + L + +LFGE + +LV + RS +E +E
Sbjct: 674 GGRGASVS------LAPGSLPWDQALFGEGSSRILVSVDPAQRSPWEAYLE 718
>gi|15894932|ref|NP_348281.1| bifunctional enzyme phosphoribosylformylglycinamidine (FGAM)
synthase (synthetase domain/glutamine amidotransferase
domain) [Clostridium acetobutylicum ATCC 824]
gi|15024615|gb|AAK79621.1|AE007675_1 phosphoribosylformylglycinamidine (FGAM) synthase [Clostridium
acetobutylicum ATCC 824]
Length = 1255
Score = 273 bits (697), Expect = 4e-71, Method: Composition-based stats.
Identities = 238/806 (29%), Positives = 366/806 (45%), Gaps = 86/806 (10%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTE-KRPCTDAEFETIAQTWSEHCVHKTFKA 59
M+++EL + A+ + +++ RE++K E KR T E + I WS+HC H TF+
Sbjct: 176 MSEDELKVFLDSNGLAMSMEDLKFCREYFKNEEKRNPTITEIKVIDTYWSDHCRHTTFQT 235
Query: 60 K---IDIDGTSLTEEQKKAYPG---------------LCVNSI----IKTYIKKA----- 92
+ I + TE K AY +C+ I +K KK
Sbjct: 236 RLQNIQFEDGKYTEVLKSAYKNYVDARKYVYGNKEKEVCLMDIAVIGMKELKKKGFLNDL 295
Query: 93 --TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDV 150
+D+I+A S V +A + DEK+ V FK ETHNHP+ IEPFGGA T +GG IRD
Sbjct: 296 DESDEINA----CSIVVDADVNGKDEKWLVMFKNETHNHPTEIEPFGGAATCLGGAIRDP 351
Query: 151 MGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGV 210
+ A + V G P E+ KG L K+I G G YGN++G+ T
Sbjct: 352 LSGRAYVYQAMRVTGSGDPRVRIEDTTKGRLPQKKITLGAANGYSSYGNQIGLATGQVSE 411
Query: 211 HYHEAYASNPLVYCGCAGIAPRGK-HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDA 269
Y E + + + G AP+ R +P D +I LGG+TGRDG GAT SS D
Sbjct: 412 CYDEGFIAKRMEVGAVVGAAPKENVVREEPKPSDVVILLGGRTGRDGCGGATGSSKEHDV 471
Query: 270 STGDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASALGCDV 329
++ G+ VQ G ++K+ + + + L D GAGG S A+GE+ G D+
Sbjct: 472 NSLQNCGAEVQKGNAPTERKLQRLFRNNKVSTLIKRCNDFGAGGVSVAIGELTD--GLDI 529
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
+L +P KY+GL EL +SE+QERM + V E + D ++E + + T
Sbjct: 530 NLDLVPKKYEGLDGTELAISESQERMAVVVEKKDAEKFIEYADKENLEAVIVAKVTDTKR 589
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKA---APPKDGKPFIKYPEYKEPDLNAALKAVI 446
L++ + I+N+S FL + ++ + AP K+ F E K D+ + +
Sbjct: 590 LKLFWKGNAIVNISRAFLDTNGVRQNVDVFVKAPKKEDNYF--KTENKNKDVKEEVLETL 647
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQD--AAVIKPMETEGKKAVAISNA 504
V S++ + +D + GTVL P+ G P + AA + + E ++
Sbjct: 648 RDLNVCSQKGLSERFDSTIGAGTVLMPFGGKNQITPAEGMAAKLPVLNGETSTGTVMTYG 707
Query: 505 LNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMA- 563
NP+ G P+ A A+ E++ V G D +KT + N+ W A
Sbjct: 708 YNPKIGKWSPFHGAMYAVIESLTKIVCMGGDYKKTRLTFQEYFERLNKEPERWGKPFAAL 767
Query: 564 RSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKK 623
+F TP I GKDS + ++ +++PP+L+ A+ +V DI V +FKK
Sbjct: 768 LGALKAQEIFNTPAIGGKDSMSGTFMD-----LNVPPTLVSFAVNVV-DINNVISPEFKK 821
Query: 624 EGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSC 683
GS++ LV + + VP F E + + + + I V+S
Sbjct: 822 VGSSVVLVKCER-----------------DENEVPLF-DELKKNFDTVQALIKDKKVISA 863
Query: 684 HDLSEGGLAAALYEMCLSG-IGAE-LKEDFHTRLGASKIASLFGETTGCLLVEIKEENRS 741
+ GGL AAL +MC IG E LKE+ LF G +++E++E S
Sbjct: 864 QSVRHGGLIAALSKMCFGNKIGFEMLKEE-----------ELFTPDYGSIVLELEE---S 909
Query: 742 AFEKEMEGASIYE-IGKTCGKAGLKL 766
KE+ YE IGKT + + L
Sbjct: 910 LDIKELFKDVKYEVIGKTIADSKIIL 935
>gi|27380830|ref|NP_772359.1| phosphoribosylformylglycinamidine synthase subunit II
[Bradyrhizobium japonicum USDA 110]
gi|67460946|sp|Q89IC0|PURL_BRAJA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|27353995|dbj|BAC50984.1| phosphoribosylformylglycinamidine synthetase II [Bradyrhizobium
japonicum USDA 110]
Length = 736
Score = 272 bits (695), Expect = 7e-71, Method: Composition-based stats.
Identities = 230/742 (30%), Positives = 345/742 (46%), Gaps = 80/742 (10%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ ++I + G
Sbjct: 31 REPTFTELGIFSAMWNEHCSYKS--SRIHLRGLP-------------------------- 62
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
APWV+ +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 63 --TKAPWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTM 120
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P+ + ++SGV+ GV YGN G+PTV G V +H
Sbjct: 121 GARPIACLNALSFGAPEHAKT---------RHLVSGVVAGVGGYGNSFGVPTVGGQVRFH 171
Query: 214 EAYASNPLVYCGCAGIAPRGKHRTKPSAGDH--IISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV G+A K ++G + I+ LG KTGRDG+ GA+ +S D +
Sbjct: 172 TRYDGNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGASMASAEFDDKS 231
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQ+G+P +K + E ++ ++G AI D GA G + + EM + LG D+
Sbjct: 232 EE-KRPTVQVGDPFAEKLLLEACLEIMEKGCVIAIQDMGAAGLTCSAVEMGAKGDLGVDL 290
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL +P + G++ +E+ LSE+QERM++ + +K + + + ++ +G T
Sbjct: 291 DLDAVPTRETGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFKKWGLDFAVVGYTTPSKR 350
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEP-DLNAALKAVINH 448
V+ G + +L L P + P P + E P + +AL+ +I
Sbjct: 351 FVVKHGGDVMADLPIKELGDEAPLYD-RPHVPSAALPVVHAREVMAPMGVGSALEKLIGT 409
Query: 449 HAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPR 508
+ SK + YDH + G T+ RP DAAV++ +G K +A++ + PR
Sbjct: 410 PDMCSKRWVWEQYDHVILGNTMQRP--------GGDAAVVRVQ--DGPKGLALTVDVTPR 459
Query: 509 QGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYN 568
DP+ A+ EA RN A G P AI DN G+P RPE M + +
Sbjct: 460 YCEADPFEGGKQAVAEAWRNITAVGGKP--LAITDNLNFGNPERPEIMGQFVGCLKGISE 517
Query: 569 TALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAI 628
P +SG S NE + G+ + PS I +G++ D + FK EG AI
Sbjct: 518 ACRTLDFPVVSGNVSLYNE---TNGRAILPTPS--IGGVGLLDDFTKSASLAFKAEGEAI 572
Query: 629 YLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV-----LSC 683
L+G+ G SV+ L I E A PP A +K + + ++G++ +
Sbjct: 573 LLIGETHGWLGQSVY--LRDICGREEGAPPPVDLAA----EKRNGDCVRGMIHAGTATAV 626
Query: 684 HDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSA 742
HDLS+GGL AL EM + SGIGA+L A FGE LV + E
Sbjct: 627 HDLSDGGLLIALAEMAMASGIGAKL---LAAPTSLVSQAYWFGEDQARYLVTVPETEAGR 683
Query: 743 FEKEMEGASI--YEIGKTCGKA 762
+M G + IG T G A
Sbjct: 684 VLAKMRGCEVPCVRIGTTGGDA 705
>gi|149194633|ref|ZP_01871729.1| phosphoribosylformylglycinamidine synthase subunit II [Caminibacter
mediatlanticus TB-2]
gi|149135377|gb|EDM23857.1| phosphoribosylformylglycinamidine synthase subunit II [Caminibacter
mediatlanticus TB-2]
Length = 740
Score = 272 bits (695), Expect = 8e-71, Method: Composition-based stats.
Identities = 224/732 (30%), Positives = 344/732 (46%), Gaps = 80/732 (10%)
Query: 40 EFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAP 99
E + WSEHC +K+ K + K +P +AP
Sbjct: 39 ELGIFSAMWSEHCSYKSSKIYL------------KGFP------------------TEAP 68
Query: 100 WVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFA 159
WV+ +NAG+I+ FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A
Sbjct: 69 WVIQGPGENAGVIDIGGNMAAVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPVA 128
Query: 160 VTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASN 219
+ + F H ++ N LH K ++SGV+ G+ YGN +G+PT+ G + ++Y N
Sbjct: 129 NLNAIRFAHIES---NDEIAKLH-KHLLSGVVAGIAGYGNCIGVPTIGGETAFEDSYKGN 184
Query: 220 PLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGS 277
LV GI + + + G+ +I +G KTGRDGL GA SS D
Sbjct: 185 ILVNAFALGICKQDEIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMSSDSFKEGDED-QRP 243
Query: 278 SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIP 335
+VQ+G+P +K + E ++ I D GA G +S+ EMAS G + L K+P
Sbjct: 244 TVQVGDPFTEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMASKSRSGLKMYLDKVP 303
Query: 336 VKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFG 395
++ +G+ P+EL LSE+QERM+I + + ++ D++ +G T V+ + +
Sbjct: 304 MREEGMNPYELMLSESQERMLICAKKGYEDKVIEIFKKYDLDAEVIGEVTDSGVVELYWH 363
Query: 396 EKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKE 455
+++ + G + P+ P D IK E E +L A + +I V K
Sbjct: 364 GEKVAEVPVGPITDEAPELCRPVKEP-DYLKEIKNIEIPEIELQKAFEEMIKLPEVVDKA 422
Query: 456 DIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPY 515
I YD V TV D +V+ E K + +S N R ++P
Sbjct: 423 WIYEQYDSMVGTSTV--------DTKRVDGSVL--WVKENNKFLGMSADCNARFCYINPR 472
Query: 516 AAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKT 575
AA+A+ EA RN P+ AI D G+P PE MW E T
Sbjct: 473 LGAAAAVMEAGRNVAVKKITPK--AITDCLNFGNPENPEIMWQFKEACEGIKEACRELNT 530
Query: 576 PFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQ 635
P +SG S NE +EG+ V P + + +G D R S+ KKEG++IY++G+ +
Sbjct: 531 PVVSGNVSLYNE---NEGEGVYPTPEIAMVGVG---DSFR--SSELKKEGNSIYILGETK 582
Query: 636 FSFGGSVFAELFGIPSGESAAVPP---FKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLA 692
FGGS++ + F + + A + P FKKE L++ L S+ L+ S D+S GG+A
Sbjct: 583 SEFGGSLYLKTF---TNKVAGIHPEVDFKKELI-LWEVLQSD----LIASAKDISTGGIA 634
Query: 693 AALYE-MCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGAS 751
A Y+ C+S + + + + +F E+ LVEI+ +N FEK +
Sbjct: 635 IAAYKWACIS------DKCLNLNIKVNDKKDIFSESLSRALVEIEPQNEEEFEKLCKEKG 688
Query: 752 IY--EIGKTCGK 761
IY +IG G+
Sbjct: 689 IYFEKIGSVGGE 700
>gi|56551716|ref|YP_162555.1| phosphoribosylformylglycinamidine synthase subunit II [Zymomonas
mobilis subsp. mobilis ZM4]
gi|59803045|sp|Q9REQ6|PURL_ZYMMO Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|56543290|gb|AAV89444.1| phosphoribosylformylglycinamidine synthase II [Zymomonas mobilis
subsp. mobilis ZM4]
Length = 734
Score = 271 bits (694), Expect = 9e-71, Method: Composition-based stats.
Identities = 212/672 (31%), Positives = 324/672 (48%), Gaps = 54/672 (8%)
Query: 107 DNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCF 166
+NAG+++ + FK E+HNHPS IEP+ GA TGVGG++RDV + ARP A + L F
Sbjct: 75 ENAGVVDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVANLNALRF 134
Query: 167 GHPDTPAENVPKGTLHPK--RIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYC 224
G P HPK ++SGV+ G+ YGN +G+PTV G V++H AY N LV
Sbjct: 135 GSPK-----------HPKTPHLVSGVVAGIGGYGNCVGVPTVGGEVNFHPAYDGNNLVNA 183
Query: 225 GCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG 282
G+A K + AG+ I+ +G KTGRDG+ GAT +S + +VQ+G
Sbjct: 184 MTVGVAETNKIFYSAASGAGNPIVYVGSKTGRDGIHGATMASADF-GKDAEEKRPTVQVG 242
Query: 283 EPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIPVKYQG 340
+P +K + E ++ AI D GA G +S+ EMAS +G ++D+ +P + +G
Sbjct: 243 DPFSEKLLIEACLELMASDAIVAIQDMGAAGLTSSAVEMASKGEVGIELDMDMVPCREEG 302
Query: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII 400
+ P+E+ LSE+QERM++ + + + + +++ +GR T K ++
Sbjct: 303 MTPYEMMLSESQERMLMVLKPGREAEAEAIFKKWELDFAIIGRVT---------DSKHMV 353
Query: 401 NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYK-------EPDLNAALKAVINHHAVNS 453
G + P L P +P++ P+ K + L ++ + S
Sbjct: 354 LTWKGDIVCDIPLAPLADNAPCYDRPWVATPKAKALGAVPASGSITDNLVTLVGSPDLAS 413
Query: 454 KEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLD 513
+ I YD+ V TV P DAAV++ TE KA+A+S + PR D
Sbjct: 414 RRWIWEQYDNMVGADTVQCP--------GGDAAVVRVHGTE--KALAMSVDVTPRYCRAD 463
Query: 514 PYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVF 573
P A+ E RN A GA P + NF G+P RPE M ++ +
Sbjct: 464 PEEGGKQAVAECYRNITAVGALPLASTDCLNF--GNPERPEIMGQIVGAIKGIGEACRAL 521
Query: 574 KTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGK 633
P +SG S NE +G ++I P+ I +G++ D FK G IYLVG
Sbjct: 522 DMPIVSGNVSLYNETRQDDGSSLAILPTPTIGGVGLLQDWRDSTTIAFKNTGEEIYLVGN 581
Query: 634 P-QFSFGGSVF-AELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGL 691
Q G S++ E+ G G + +V +++A + + + I G++ + HD+S+GGL
Sbjct: 582 SGQGHLGQSIWLREIAGREEGTAPSVDLAQEKATGDF--IRAMIQDGMLCAVHDISDGGL 639
Query: 692 AAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGA 750
A AL EM L+G IGA ++ H + A A FGE G LV E G
Sbjct: 640 AVALAEMALAGNIGATVEA--HDKAIAEH-AYYFGEDQGRYLVSSTNAVALVSAAEKAGI 696
Query: 751 SIYEIGKTCGKA 762
++ +G T G A
Sbjct: 697 PVFRLGVTGGDA 708
>gi|154253027|ref|YP_001413851.1| phosphoribosylformylglycinamidine synthase II [Parvibaculum
lavamentivorans DS-1]
gi|154156977|gb|ABS64194.1| phosphoribosylformylglycinamidine synthase II [Parvibaculum
lavamentivorans DS-1]
Length = 739
Score = 271 bits (694), Expect = 9e-71, Method: Composition-based stats.
Identities = 220/734 (29%), Positives = 338/734 (46%), Gaps = 85/734 (11%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ K + T+
Sbjct: 32 REPTLTELGIFSAMWNEHCSYKSSKKWLRTLPTT-------------------------- 65
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
P V+ +NAG+++ + + FK E+HNHPS IEP GA TGVGG++RDV +
Sbjct: 66 ----GPRVICGPGENAGVVDIGDGQAIIFKMESHNHPSYIEPHEGAATGVGGILRDVFTM 121
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG PD P + I+SGV+ G+ YGN G+PT+ G V++
Sbjct: 122 GARPVAALNALRFGAPDHP---------RTRHIVSGVVAGIGGYGNSFGVPTIGGEVNFD 172
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
+Y N LV AG+A K + G I+ LG KTGRDG+ GAT +S ++
Sbjct: 173 PSYNGNCLVNAFAAGLADADKIFYSEAKGVGLPIVYLGSKTGRDGIHGATMASAEFGENS 232
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
+ +VQIG+P +K + E ++ G AI D GA G + + EM + LG ++
Sbjct: 233 EE-KRPTVQIGDPFSEKLLLEACLELMASGAVIAIQDMGAAGLTCSAVEMGAKGDLGVEL 291
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL K+P + G+ +E+ LSE+QERM++ + K + + + ++ +G+ T D
Sbjct: 292 DLDKVPCREDGMTAYEMMLSESQERMLMVLDPAKEKEAEAIFVKWGLDFAIIGKTTDDLR 351
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFIK--YPEYKEP-------DLNA 440
R++ + + +L P + L P+ +P+I PE +P ++
Sbjct: 352 FRIKRHGQVMADL---------PIKDLGDQAPEYDRPWIAPVKPEPLDPSSVPAPNNIGE 402
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
L ++ + S+ + YDH +QG T + GP G DAAVI+ G K +A
Sbjct: 403 ILVRMLGLPDMCSRRWVWEQYDHLIQGNTAI----GPGG----DAAVIRV--ERGPKGLA 452
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
+ + PR DP A+ E RN A GA+P AI DN G+P +P+ M +
Sbjct: 453 FTLDVTPRYCAADPREGGKQAVAECWRNLTAVGAEP--LAITDNLNFGNPEKPDIMGQFV 510
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ P +SG S NE + GK I P+ I A+G++ +
Sbjct: 511 GCIEGIGDACRALDFPVVSGNVSLYNE---TNGK--GILPTPAIGAVGLLDNFEERVTIA 565
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKK-LHSNIMKGL 679
FK EG AI L+G+ + G S++ + + +A PP + + I G
Sbjct: 566 FKAEGEAIVLIGETKGHLGQSIYLRDIAGKTDDRSAPPPVDLAVERRNGDFVRAEIRAGR 625
Query: 680 VLSCHDLSEGGLAAALYEMCLS-GIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEE 738
+ HD+S+GG+ AL EM ++ GIGA +K + L A FGE LV + E
Sbjct: 626 TTAVHDISDGGILVALAEMAMAGGIGASVKPETALPLHAWA----FGEDQARYLVTMPEN 681
Query: 739 NRSAFEKEMEGASI 752
AF E A I
Sbjct: 682 EAKAFIARAEKAGI 695
>gi|78183587|ref|YP_376021.1| phosphoribosylformylglycinamidine synthase subunit II
[Synechococcus sp. CC9902]
gi|110831831|sp|Q3B100|PURL_SYNS9 Phosphoribosylformylglycinamidine synthase 2
(Phosphoribosylformylglycinamidine synthase II) (FGAM
synthase II)
gi|78167881|gb|ABB24978.1| Phosphoribosylformylglycinamidine synthase II [Synechococcus sp.
CC9902]
Length = 766
Score = 271 bits (694), Expect = 1e-70, Method: Composition-based stats.
Identities = 217/679 (31%), Positives = 335/679 (49%), Gaps = 61/679 (8%)
Query: 97 DAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSAR 156
+ P +L +NAG+++ + + ++FK E+HNHPSA+EPF GA TGVGG++RD+ + AR
Sbjct: 65 EGPRILVGPGENAGVVDLGDGHRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGAR 124
Query: 157 PFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAY 216
P A+ + L FG D A NV ++ GV+ G+ YGN +G+PTV G V + +Y
Sbjct: 125 PIALLNALRFGPLDDSA-NVG--------LMEGVVAGIAHYGNCVGVPTVGGEVAFDPSY 175
Query: 217 ASNPLVYCGCAGIAPRGKHRTKPSA---GDHIISLGGKTGRDGLRGATFSSMVMDASTGD 273
+ NPLV G+ K K A G+ ++ +G TGRDG+ GA+F+S + A + D
Sbjct: 176 SGNPLVNAMALGLM-ETKDIVKSGAIGVGNPVVYVGSTTGRDGMGGASFASAELSADSLD 234
Query: 274 VAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMAS--ALGCDVDL 331
+VQ+G+P ++K + E ++A D G A D GA G + + EMA+ LG ++DL
Sbjct: 235 -DRPAVQVGDPFLEKGLIEACLEAFDSGDVVAAQDMGAAGLTCSCSEMAAKGGLGVELDL 293
Query: 332 AKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLR 391
++P + G+ +E LSE+QERM+ V + E L K ++ +G+ + ++R
Sbjct: 294 DRVPARESGMTAYEFLLSESQERMLFVVKAGREEPLMKRFRRWGLQAAVVGQVLEEPIVR 353
Query: 392 VRFGEKEIINLSCGFLHSGPPQRK--LKAAPPKDGKPFIKYPEYKEPDL---NAALKAVI 446
V + + L P K L + PP D + ++ E + PDL AAL ++
Sbjct: 354 VLHHGEVAAEVPATALADDTPIEKHALLSEPPVDLQEHWQWTEAQLPDLADPAAALLGLL 413
Query: 447 NHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVI--KPMETEGK-----KAV 499
+ + SK + R YD +V TV+ + DAAVI +P + +G + V
Sbjct: 414 DDPTIASKRWVHRQYDQQVLANTVV-------SSGAADAAVIRLRPQQGDGSLKTTTRGV 466
Query: 500 AISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWAL 559
A + R LDP A +A+ EA RN G++P AI DN P P+ W L
Sbjct: 467 AATVDCPNRWVALDPERGAMAAVAEAARNLSCVGSEP--LAITDNLNFPSPETPKGFWQL 524
Query: 560 IEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGS 619
R F+TP G S NE +G I P+ +I +G+V DI +V G
Sbjct: 525 AMACRGISEACKAFQTPVTGGNVSLYNETRRDDGSLQPIHPTPVIGMVGVVDDITKVTGL 584
Query: 620 DFKKEGSAIYLVG-KP------QFSFGGSVFAEL-FGIPSGESAAVPP-----FKKEAAE 666
+ + G + L+G KP + GS + + G +G PP +K
Sbjct: 585 GWCQPGDVVVLLGVKPDADQDDRVGLAGSSYQQFTLGTITGR----PPRIDFDLEKRVQG 640
Query: 667 LYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL-SGIGAELKEDFHTRLGASKIASLFG 725
L ++ I GL+ S HD S+GGLA AL E + SG G EL T S LF
Sbjct: 641 LVRQA---IADGLIASAHDSSDGGLAVALAECSIASGFGVELTLSVGT---MSPARLLFA 694
Query: 726 ETTGCLLVEIKEENRSAFE 744
E ++V +K + + ++
Sbjct: 695 EGGARVVVSVKADQLTRWQ 713
>gi|148543379|ref|YP_001270749.1| phosphoribosylformylglycinamidine synthase II [Lactobacillus
reuteri F275]
gi|148530413|gb|ABQ82412.1| phosphoribosylformylglycinamidine synthase II [Lactobacillus
reuteri F275]
Length = 742
Score = 271 bits (693), Expect = 1e-70, Method: Composition-based stats.
Identities = 229/773 (29%), Positives = 363/773 (46%), Gaps = 90/773 (11%)
Query: 1 MNDEELLALSNERRAALDIYEMRAIREFYKTE--KRPCTDAEFETIAQTWSEHCVHKTFK 58
M EE+ E++ LD A ++ +T+ R E + WSEHC +K
Sbjct: 5 MTPEEI----KEKKPYLDWSLTEAEYDYIRTQLLGRLPNYTETGLFSAMWSEHCSYK--- 57
Query: 59 AKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPWVLSSFVDNAGIIEFDEKY 118
K+ P +++ + K + P + AG+++ D+
Sbjct: 58 ---------------KSKP------VLRLFPNKNERVLQGPG------EGAGVVDIDDGQ 90
Query: 119 EVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLCFGHPDTPAENVPK 178
V FKAE+HNHP+ +EP+ GA TGVGG++RD+ + ARP A D L FG D +
Sbjct: 91 AVVFKAESHNHPTTVEPYQGAATGVGGILRDIFSMGARPIASLDSLHFGELDNSTTRMK- 149
Query: 179 GTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTK 238
++ + G+ DYGN MGIPT+ G + Y N L G+ + +
Sbjct: 150 --------VTNTVRGIGDYGNCMGIPTIAGETTFDPCYQGNILCNAMSVGLMDQKDIQQG 201
Query: 239 PSA--GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLID 296
+A G+ ++ +G KTGRDG+ GATF+S + S+VQ+G P ++K + E +D
Sbjct: 202 RAAGIGNAVMYVGAKTGRDGIHGATFASADFN-DENMTQRSAVQVGNPFMEKLLLEACLD 260
Query: 297 -ARDQGLY-SAITDCGAGGYSSAVGEMAS--ALGCDVDLAKIPVKYQGLAPWELWLSEAQ 352
R+ + I D GA G S+ EMAS G +++L +P + G++ +E+ LSE+Q
Sbjct: 261 LIRNHPDWLVGIQDMGAAGIVSSSAEMASEGQSGMELNLDLVPQREPGMSAYEIMLSESQ 320
Query: 353 ERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIINLSCGFLHSGPP 412
ERM++ V E ++K+ D D+E +GR T + +E+ ++ L
Sbjct: 321 ERMLLCVKKGHEEDVKKIFDFYDLEAVTIGRITAGHDYVLFHDGEEVCHIPVSSLTDDVL 380
Query: 413 QRKLKAAPPKDGKPFIKYPEYKEPDLN---AALKAVINHHAVNSKEDIVRLYDHEVQGGT 469
+ + P + + P + PD++ L A++ + K + + YD +V+ T
Sbjct: 381 EEESLEKKPARIELAEQQPAWI-PDIDNVAEVLTALLAQSTIADKSSLYQQYDSQVRTNT 439
Query: 470 VLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASAIDEAVRNA 529
V P DA V++ T K +A++ N R L P A+ EA N
Sbjct: 440 VAGP--------GSDAGVLRIRGTH--KGLAMTTDGNGRFVYLSPEVGGQIALVEAAANI 489
Query: 530 VAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYL 589
+A+GA+P AI D GDP PE W L + + + F TP ISG S NE
Sbjct: 490 IASGAEP--LAITDCLNYGDPTDPEIFWELHQSVQGMADACREFNTPVISGNVSLYNE-- 545
Query: 590 SSEGKRVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGI 649
+ G+ +I P+ ++ +G++ +I RV S + G +YLVG+ + + GS EL +
Sbjct: 546 -NNGQ--AIHPTPMVGMVGLIKNIDRVIPSFVQHPGDKVYLVGQTRDDYAGS---ELQKM 599
Query: 650 PSGE-SAAVPPFKKEAAELY-KKLHSNIMKGLVLSCHDLSEGGLAAALYEMCLS---GIG 704
+G+ S V F Y ++L + + GLV S HDLSEGGL AL E G+
Sbjct: 600 MTGDISGIVESFDLHHVHQYMQRLLTTMENGLVSSAHDLSEGGLGVALAETVFKTDLGLK 659
Query: 705 AELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGASIYEIGK 757
+L D HT A LF ET G +V + E + FE+ + G + IG+
Sbjct: 660 IDLA-DQHT-------ARLFSETPGRFIVTVAPEKATEFEQVL-GKDAHLIGE 703
>gi|15811163|gb|AAL08837.1|AF308671_1 hypothetical phosphoribosylformylglycinamidine synthase [Cowdria
ruminantium]
Length = 521
Score = 271 bits (693), Expect = 1e-70, Method: Composition-based stats.
Identities = 174/495 (35%), Positives = 271/495 (54%), Gaps = 30/495 (6%)
Query: 283 EPIIQKKVAEVLI-DARDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGL 341
+PI QKK+++ +I +ARD LY+AITD GAGG SS++GEM + G V+L K+ +K++ +
Sbjct: 1 DPITQKKLSDAIIKEARDLNLYNAITDNGAGGLSSSIGEMGNN-GFKVELNKVLLKHKNM 59
Query: 342 APWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEIIN 401
PWE+W+SE+QERM +A+P K +K+ +DVE++ +G F V + + I++
Sbjct: 60 LPWEIWVSESQERMTLAIPPSKFPIFEKIMKKHDVEISIIGTFNNTKKAVVSYNDSIIMD 119
Query: 402 LSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHAVNSKEDIVRLY 461
+ FLH+G P+ LK P + + + +P L+ L ++ + SKE I Y
Sbjct: 120 MDINFLHNGIPKTHLKTIPWSNIISSVVDTLHNKP-LDTELNEMMQRMNICSKEFISTQY 178
Query: 462 DHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAISNALNPRQGLLDPYAAAASA 521
DHEVQG +V++P G +G V +A VI+P+ + ++ + S+ L G + Y AA A
Sbjct: 179 DHEVQGTSVIKPIQG-KGRVDGEAIVIRPILSS-ERGLVKSHGLGSSYGEISTYHMAACA 236
Query: 522 IDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALIEMARSCYNTALVFKTPFISGK 581
ID A+RN +A G + A+LDNFC D P+ +W L A++CY A +FKTPFISGK
Sbjct: 237 IDTAIRNYIAIGGNFHHLALLDNFCWCDSTNPKRLWQLKNAAQACYEYAKIFKTPFISGK 296
Query: 582 DSFNNEYLSSEGK----RVSIPPSLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFS 637
DS N++ K +S PPSLLIS +GI+ +I D K G IY++G
Sbjct: 297 DSMFNDFKGYNNKGEPINISAPPSLLISTVGIIENIHNAITLDVKNPGDLIYILGVTYDE 356
Query: 638 FGGSVFAELFGIPSGESAAVPPFK-KEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALY 696
G S + + G+ + VP + K A +LYK + + ++ S L+ GGL L
Sbjct: 357 LGRSEYQKYSGLGNNN---VPQVRAKHAKKLYKLYSNAVNTNIIASAIALNLGGLIIGLI 413
Query: 697 EMCLSG-IGAELK---------EDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFE-- 744
+ + G +GA++ ED + + + LF E+ +LV I N+ FE
Sbjct: 414 KSLIGGELGAKIDLSLVPTHNIEDNNIK----EKVILFSESQSRILVTIAPHNKQKFETI 469
Query: 745 -KEMEGASIYEIGKT 758
K++ A+I I T
Sbjct: 470 FKDIAHANIGIISDT 484
>gi|39934667|ref|NP_946943.1| phosphoribosylformylglycinamidine synthase subunit II
[Rhodopseudomonas palustris CGA009]
gi|67460822|sp|Q6N9F2|PURL_RHOPA Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
gi|39648517|emb|CAE27038.1| phosphoribosylformylglycinamide synthetase [Rhodopseudomonas
palustris CGA009]
Length = 736
Score = 271 bits (692), Expect = 2e-70, Method: Composition-based stats.
Identities = 231/750 (30%), Positives = 353/750 (47%), Gaps = 96/750 (12%)
Query: 34 RPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKAT 93
R T E + W+EHC +K+ ++I + G
Sbjct: 32 REPTFTELGIFSAMWNEHCSYKS--SRIHLKGLP-------------------------- 63
Query: 94 DDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGV 153
APWVL +NAG+I+ + V FK E+HNHPS IEP+ GA TGVGG++RDV +
Sbjct: 64 --TKAPWVLQGPGENAGVIDIGDNQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTM 121
Query: 154 SARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYH 213
ARP A + L FG P P + ++SGV+ GV YGN G+PTV G +H
Sbjct: 122 GARPIACLNALSFGDPSHPKT---------RHLVSGVVAGVGGYGNSFGVPTVGGQTRFH 172
Query: 214 EAYASNPLVYCGCAGIAPRGK--HRTKPSAGDHIISLGGKTGRDGLRGATFSSMVMDAST 271
Y N LV G+A K G I+ LG KTGRDG+ GAT +S D +
Sbjct: 173 TRYDGNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGMGGATMASAEFDEGS 232
Query: 272 GDVAGSSVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDV 329
D +VQ+G+P +K + E ++ + AI D GA G + + EM + LG ++
Sbjct: 233 -DEKRPTVQVGDPFAEKLLLEACLEIMAKDCVIAIQDMGAAGLTCSAVEMGAKGDLGVEL 291
Query: 330 DLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAV 389
DL +P + G+ +E+ LSE+QERM++ + +K + +++ ++ +G T
Sbjct: 292 DLDAVPTRETGMTAYEMMLSESQERMLMVLKPEKEKEAEEIFKKWGLDFAIVGYTTPTKR 351
Query: 390 LRVRFGEKEIINLSCGFLHSGPPQRKLKAAPPKDGKPFI---KYPEYKEPDLNA------ 440
V+ G G + + P ++L P +P++ + P D+NA
Sbjct: 352 FVVKHG---------GQVKADLPIKELGDEAPLYDRPWVESERLPVIHARDINAPMGAAE 402
Query: 441 ALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA 500
AL+ ++ + SK + YDH + G TV RP DAAV++ +G K +A
Sbjct: 403 ALEKLLATPDLCSKRWVWEQYDHVIGGNTVQRP--------GGDAAVVRI--EDGPKGLA 452
Query: 501 ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPETMWALI 560
++ + PR DP+ A+ EA RN A G P AI DN G+P RPE M L+
Sbjct: 453 LTVDVTPRYCEADPFEGGKQAVAEAYRNITAVGGKP--LAITDNLNFGNPERPEIMGQLV 510
Query: 561 EMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSD 620
+ + +P +SG S NE + G+ + PS I +G++ D +
Sbjct: 511 GCLKGISEACIALDSPIVSGNVSLYNE---TSGRGILPTPS--IGGVGVLDDFTKSATLA 565
Query: 621 FKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGLV 680
FK EG AI L+G+ + G SV+ L I E A PP +K H ++++G++
Sbjct: 566 FKAEGEAILLIGETKGWLGQSVY--LREICGREEGAPPPVDLAV----EKRHGDVVRGMI 619
Query: 681 -----LSCHDLSEGGLAAALYEMCLSG-IGAELKEDFHTRLGASKIASLFGETTGCLLVE 734
+ HD+S+GGL A+ EM ++G IGA L + A FGE +V
Sbjct: 620 HAGTATAVHDVSDGGLLVAIAEMAIAGNIGASLDAPPGETVSH---AWWFGEDQARYVVT 676
Query: 735 IKEENRSAFEKEME--GASIYEIGKTCGKA 762
+KE + A + +++ G +IG T G A
Sbjct: 677 VKEADLLAVKTKLKTIGVPCTQIGVTGGHA 706
>gi|111021806|ref|YP_704778.1| phosphoribosylformylglycinamidine synthase II [Rhodococcus sp.
RHA1]
gi|110821336|gb|ABG96620.1| phosphoribosylformylglycinamidine synthase II [Rhodococcus sp.
RHA1]
Length = 761
Score = 270 bits (691), Expect = 2e-70, Method: Composition-based stats.
Identities = 226/734 (30%), Positives = 355/734 (48%), Gaps = 86/734 (11%)
Query: 33 KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKA 92
+RP T+AE + WSEHC +K+ K + G + T+E + +
Sbjct: 41 RRP-TEAELAMYSVMWSEHCSYKSSKVHLKYFGETTTDEMRSS----------------- 82
Query: 93 TDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDVMG 152
+L+ +NAG+++ + + V+FK E+HNHPS +EP+ GA TGVGG++RD+M
Sbjct: 83 --------MLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMA 134
Query: 153 VSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHY 212
+ ARP AV D L FG D P +R++ GV+ GV YGN +G+P V G +
Sbjct: 135 MGARPIAVMDQLRFGAADAP---------DTRRVVDGVVRGVGGYGNSLGLPNVGGETVF 185
Query: 213 HEAYASNPLVYCGCAG-IAPRGKHRTKPS-AGDHIISLGGKTGRDGLRGATFSSMVMDAS 270
E+YA NPLV CAG + H S AG+ II G +TG DG+ G S + +
Sbjct: 186 DESYAGNPLVNALCAGAMRVEDLHLAFASGAGNKIILFGARTGLDGIGGV--SVLASETF 243
Query: 271 TGDVAGS------SVQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGEMASA 324
GD +G+ +VQ+G+P +K + E ++ L I D G G S A E+A+A
Sbjct: 244 DGDESGTGRKKLPAVQVGDPFTEKVLIECCLELYAAKLVVGIQDLGGAGLSCATSELAAA 303
Query: 325 --LGCDVDLAKIPVKYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
G ++L ++P++ G+ E+ SE+QERM V D ++A ++C DV T +G
Sbjct: 304 GDGGMHINLEQVPMRATGMTAAEVLSSESQERMCAVVTPDNVDAFMEVCKKWDVLATVIG 363
Query: 383 RFTGDAVLRVRFGEKEIINLSCGFL-HSGPP-QRKLKAAPPKDG-----KPFIKYPEYKE 435
T L + + + ++++ + H GP +R ++ +D + PE +
Sbjct: 364 EVTDGERLTISWHGETVVDVPPRTVAHEGPVYERPVQRPASQDALVANTTAGLTRPESAD 423
Query: 436 PDLNAALKAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEG 495
+L A L ++ A+ S++ I YD V+G TVL D+ VI+ E G
Sbjct: 424 -ELKATLLKMLASPALCSRKWITEQYDRYVRGNTVLAE--------NADSGVIRVDEKTG 474
Query: 496 KKAVAISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDPNRPET 555
+ +A++ + R LDPYA A A+ EA RN GA P+ + NF G P P
Sbjct: 475 -RGIALATDASGRYTALDPYAGAQLALAEAFRNVAVTGATPKAVSNCLNF--GSPEDPGV 531
Query: 556 MWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIG- 614
MW + R + P G SF N+ S+ I P+ +++ +G++ D+
Sbjct: 532 MWQFQQAVRGLADGCAKLGIPVTGGNVSFYNQTGST-----PILPTPVVAVLGVIDDVHR 586
Query: 615 RVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAE--LYKKLH 672
R+P + G + L+G + F GS++++ + G VPP E L L
Sbjct: 587 RIPTGLGLEPGETLILLGDTRDEFDGSIWSQ---VEHGHLGGVPPKVDLEREQLLADILL 643
Query: 673 SNIMKGLVLSCHDLSEGGLAAALYEMCLSG-IGAE--LKEDFHTRLGASKIASLFGETTG 729
+ GLV + HDLSEGGLA + E L+G G L +D A +LF E++G
Sbjct: 644 AASRDGLVSAAHDLSEGGLAQTVVEAALAGETGCRILLPDD------ADPFVTLFSESSG 697
Query: 730 CLLVEIKEENRSAF 743
+LV + + F
Sbjct: 698 RVLVAVPRTEETRF 711
Score = 72.0 bits (175), Expect = 2e-10, Method: Composition-based stats.
Identities = 70/286 (24%), Positives = 123/286 (43%), Gaps = 33/286 (11%)
Query: 108 NAGIIEFDEKYE--VSFKAETHNHPSAIEPFGGANTGVGGVIRDVMGVSARPFAVTDVLC 165
++G+I DEK ++ + +A++P+ GA + R+V A P AV++ L
Sbjct: 463 DSGVIRVDEKTGRGIALATDASGRYTALDPYAGAQLALAEAFRNVAVTGATPKAVSNCLN 522
Query: 166 FGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCG 225
FG P+ P G + + G+ D K+GIP G V ++ S P++
Sbjct: 523 FGSPEDP------GVMWQ---FQQAVRGLADGCAKLGIPVTGGNVSFYNQTGSTPILPTP 573
Query: 226 CAGI--APRGKHRTKPSA-----GDHIISLGGKTGRDGLRGATFSSMVMDASTGDVAGSS 278
+ HR P+ G+ +I LG RD G+ +S + G + G
Sbjct: 574 VVAVLGVIDDVHRRIPTGLGLEPGETLILLGDT--RDEFDGSIWSQV----EHGHLGGVP 627
Query: 279 VQIGEPIIQKKVAEVLIDARDQGLYSAITDCGAGGYSSAVGE--MASALGCDVDLAKIPV 336
++ + ++ +A++L+ A GL SA D GG + V E +A GC + L
Sbjct: 628 PKV-DLEREQLLADILLAASRDGLVSAAHDLSEGGLAQTVVEAALAGETGCRILLP---- 682
Query: 337 KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLG 382
P+ SE+ R+++AVP + +C A ++ +G
Sbjct: 683 --DDADPFVTLFSESSGRVLVAVPRTEETRFTGMCTARNLPWVRIG 726
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.316 0.135 0.398
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,993,739,262
Number of Sequences: 5470121
Number of extensions: 135427603
Number of successful extensions: 311748
Number of sequences better than 1.0e-05: 500
Number of HSP's better than 0.0 without gapping: 470
Number of HSP's successfully gapped in prelim test: 433
Number of HSP's that attempted gapping in prelim test: 303507
Number of HSP's gapped (non-prelim): 1697
length of query: 766
length of database: 1,894,087,724
effective HSP length: 141
effective length of query: 625
effective length of database: 1,122,800,663
effective search space: 701750414375
effective search space used: 701750414375
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 134 (56.2 bits)