Alternate Experiment Names
US-1
RADIAT
Experiment Type
Research Area
Radiation biology
Principal Investigator
Co-Investigators
Experiment Description
Objectives:One of the major features of the space environment is the presence of cosmic rays or HZE (high energy and charge) particles. Understanding the biological effects of the complex radiation environment in space is crucial to the safety of spaceflight crews. Of greatest importance are changes to chromosomes which lead to the conversion of normal cells to cancer cells. The objective of this study is to isolate genetic changes in animal cells caused by cosmic rays in space so that their likelihood of occurrence and structural features can be evaluated. The soil nematode Caenorhabditis elegans was used due to its short generation time and thoroughly understood development process.
Preservation complete
No data are available to the archive for this experiment.
Medical Subject Headings (MeSH) (Keywords)
Research Specimens / Subjects
Nelson GA, Johnson TE: Caenorhabditis elegans: a model system for space biology studies. Experimental Gerontology, vol. 26(2-3), 1991, pp. 299-309.
Nelson GA, Schubert WW, Kazarians GA, Richards GF: Development and chromosome mechanics in nematodes: results from IML-1. Advances in Space Research, vol. 14(8), 1994, pp. 209-214.
Nelson GA, Schubert WW, Kazarians GA, Richards GF, Benton EV, Benton ER: Genetic and molecular dosimetry of HZE radiation. BIORACK on Spacelab IML-1, Mattock C, ed., vol. European Space Agency SP; 1162, 1995, pp. 41-50.
Nelson GA, Schubert WW, Kazarians GA, Richards GF, Benton EV, Benton ER, Henke R: Nematode radiobiology and development in space. Results from IML-1. Fifth European Symposium on Life Sciences Research in Space, vol. European Space Agency SP; 366, 1994, pp. 187-191.
Nelson GA: Genetic and molecular dosimetry of HZE radiation (7-IML-1). First International Microgravity Laboratory experiment descriptions, Miller TY, ed., NASA TM-4353 , 1992, pp. 25-31.
Nelson GA, Schubert WW, Kazarians GA, Richards GF, Benton EV, Benton ER, Henke R: Radiation effects in nematodes: results from IML-1 experiments. Advances in Space Research, vol. 14(10), Oct 1994, pp. 87-91.
Nelson GA: Radiation in microgravity. Environmental Physiology, vol. 2, 1996, pp. 785-798.
NASA Critical Path Roadmap References
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Paul Fung