Journal Publications, 2005
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November
Journal of Immunology
Allergen-Induced Airway Hyperresponsiveness Mediated by Cyclooxygenase Inhibition Is Not Dependent on 5-Lipoxygenase or IL-5, but Is IL-13 Dependent.
Peebles RS Jr, Hashimoto K, Sheller JR, Moore ML, Morrow JD, Ji S, Elias JA, Goleniewska K, O'neal J, Mitchell DB, Graham BS, Zhou W.
J Immunol. 2005 Dec 15;175(12):8253-9.
Vaccine
T-Cell Responses Directed against Multiple HLA-A*0201-Restricted Epitopes Derived from Wilms' Tumor 1 Protein in Patients with Leukemia and Healthy Donors: Identification, Quantification, and Characterization.
Rezvani K, Brenchley JM, Price DA, Kilical Y, Gostick E, Sewell AK, Li J, Mielke S, Douek DC, Barrett AJ.
Clin Cancer Res. 2005 Dec 15;11(24):8799-8807.
Journal of Virology
Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization.
Kong WP, Xu L, Stadler K, Ulmer JB, Abrignani S, Rappuoli R, Nabel GJ.
J Virol. 2005 Nov;79(22):13915-23.
Vaccine
Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein.
Epstein SL, Kong WP, Misplon JA, Lo CY, Tumpey TM, Xu L, Nabel GJ.
Vaccine. 2005 Nov 16;23(46-47):5404-10.
Journal of Experimental Medicine
Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.
Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, Roederer M, Koup RA, Migueles SA, Gostick E, Wooldridge L, Sewell AK, Connors M, Douek DC.
J Exp Med. 2005 Nov 21;202(10):1349-61
Nature Medicine
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4(+)CD25(+) regulatory T cells.
Zhang H, Chua KS, Guimond M, Kapoor V, Brown MV, Fleisher TA, Long LM, Bernstein D, Hill BJ, Douek DC, Berzofsky JA, Carter CS, Read EJ, Helman LJ, Mackall CL.
Nat Med. 2005 Nov;11(11):1238-43.
Science
Structure of a V3-containing HIV-1 gp120 core.
Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, Stanfield RL, Dimitrov DS, Korber B, Sodroski J, Wilson IA, Wyatt R, Kwong PD.
Science. 2005 Nov 11;310(5750):1025-8.
Journal of Virology
An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction.
Dey AK, Khati M, Tang M, Wyatt R, Lea SM, James W.
J Virol. 2005 Nov;79(21):13806-10.
October
Proceedings of the National Academy of Sciences
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates.
Wille-Reece U, Flynn BJ, Lore K, Koup RA, Kedl RM, Mattapallil JJ, Weiss WR, Roederer M, Seder RA.
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15190-4.
Nature Medicine
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4(+)CD25(+) regulatory T cells.
Zhang H, Chua KS, Guimond M, Kapoor V, Brown MV, Fleisher TA, Long LM, Bernstein D, Hill BJ, Douek DC, Berzofsky JA, Carter CS, Read EJ, Helman LJ, Mackall CL.
Nat Med. 2005 Oct 16; [Epub ahead of print]
Proceedings of the National Academy of Sciences
Interfacial metal and antibody recognition.
Zhou T, Hamer DH, Hendrickson WA, Sattentau QJ, Kwong PD.
Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14575-80.
Journal of Medical Primatology
Polyvalent DNA prime and envelope protein boost HIV-1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate..
Pal R, Wang S, Kalyanaraman VS, Nair BC, Whitney S, Keen T, Hocker L, Hudacik L, Rose N, Cristillo A, Mboudjeka I, Shen S, Wu-Chou TH, Montefiori D, Mascola J, Lu S, Markham P.
J Med Primatol. 2005 Oct;34(5-6):226-36.
Nature Medicine
A live-cell assay to detect antigen-specific CD4(+) T cells with diverse cytokine profiles.
Chattopadhyay PK, Yu J, Roederer M.
Nat Med . 2005 Oct;11(10):1113-7
September
Journal of Antimicrobial Therapy
Successful treatment of Acinetobacter meningitis with meropenem and rifampicin.
Gleeson T, Petersen K, Mascola J.
J Antimicrob Chemother. 2005 Sep;56(3):602-3.
Journal of Allergy and Clinical Immunology
Respiratory syncytial virus infection in the absence of STAT1 results in airway dysfunction, airway mucus, and augmented IL-17 levels.
Hashimoto K, Durbin JE, Zhou W, Collins RD, Ho SB, Kolls JK, Dubin PJ, Sheller JR, Goleniewska K, O'neal JF, Olson SJ, Mitchell D, Graham BS, Peebles RS Jr.
J Allergy Clin Immunol. 2005 Sep;116(3):550-7.
Blood
Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia.
Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM.
Blood. 2005 Sep 1;106(5):1749-54
Journal of Virology
Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus.
Forsell MN, Li Y, Sundback M, Svehla K, Liljestrom P, Mascola JR, Wyatt R, Karlsson Hedestam GB.
J Virol. 2005 Sep;79(17):10902-14.
Virology
Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d.
Koch M, Frazier J, Sodroski J, Wyatt R.
Virology. 2005 Sep 30;340(2):277-284.
Virology
HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization sensitivity.
Louder MK, Sambor A, Chertova E, Hunte T, Barrett S, Ojong F, Sanders-Buell E, Zolla-Pazner S, McCutchan FE, Roser JD, Gabuzda D, Lifson JD, Mascola JR.
Virology. 2005 Sep 1;339(2):226-38.
Nature Medicine
A live-cell assay to detect antigen-specific CD4(+) T cells with diverse cytokine profiles..
Chattopadhyay PK, Yu J, Roederer M.
Nat Med. 2005 Sep 25; [Epub ahead of print]
Trends in Immunology
Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer.
Kern F, LiPira G, Gratama JW, Manca F, Roederer M.
Trends Immunol. 2005 Sep;26(9):477-84.
August
Proceedings of the National Academy of Sciences
Toward a live microbial microbicide for HIV: Commensal bacteria secreting an HIV fusion inhibitor peptide.
Rao S, Hu S, McHugh L, Lueders K, Henry K, Zhao Q, Fekete RA, Kar S, Adhya S, Hamer DH.
Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):11993-8.
Epub 2005 Jul 22.
International Immunology
Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individuals.
Takase H, Yu CR, Mahdi RM, Douek DC, Dirusso GB, Midgley FM, Dogra R, Allende G, Rosenkranz E, Pugliese A, Egwuagu CE, Gery I.
Int Immunol. 2005 Aug;17(8):1131-40.
Infection and Immunity
Prevention and treatment of cutaneous leishmaniasis in primates by using synthetic type D/A oligodeoxynucleotides expressing CpG motifs.
Flynn B, Wang V, Sacks DL, Seder RA, Verthelyi D.
Infect Immun. 2005 Aug;73(8):4948-54.
Current Opinion in Immunology
Host-pathogen interactions in the 21st century.
Pulendran B, Seder RA.
Curr Opin Immunol. 2005 Aug;17(4):335-7.
Journal of Virology
Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.
Pancera M, Lebowitz J, Schon A, Zhu P, Freire E, Kwong PD, Roux KH, Sodroski J, Wyatt R.
J Virol. 2005 Aug;79(15):9954-69.
Journal of Virology
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies.
Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, Koutsoukos M, Voss G, Goepfert P, Gilbert P, Greene KM, Bilska M, Kothe DL, Salazar-Gonzalez JF, Wei X, Decker JM, Hahn BH, Montefiori DC.
J Virol. 2005 Aug;79(16):10108-25.
Journal of Virology
Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines.
Mascola JR, D'Souza P, Gilbert P, Hahn BH, Haigwood NL, Morris L, Petropoulos CJ, Polonis VR, Sarzotti M, Montefiori DC.
J Virol. 2005 Aug;79(16):10103-7.
July
Contemporary Topics in Laboratory Animal Science
Mammary ductal carcinoma with comedo pattern in a rhesus macaque.
Smith JM, Rao SS, Stump KC, Benazzi C, Sarli G, DeTolla LJ.
Contemp Top Lab Anim Sci. 2005 Jul;44(4):29-33.
Vaccine
Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein.
Epstein SL, Kong WP, Misplon JA, Lo CY, Tumpey TM, Xu L, Nabel GJ.
Vaccine. 2005 Jul 9; [Epub ahead of print]
Journal of Virology
Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses.
Reimann KA, Parker RA, Seaman MS, Beaudry K, Beddall M, Peterson L, Williams KC, Veazey RS, Montefiori DC, Mascola JR, Nabel GJ, Letvin NL.
J Virol. 2005 Jul;79(14):8878-85.
Journal of Virology
A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates.
Barouch DH, Yang ZY, Kong WP, Korioth-Schmitz B, Sumida SM, Truitt DM, Kishko MG, Arthur JC, Miura A, Mascola JR, Letvin NL, Nabel GJ.
J Virol. 2005 Jul;79(14):8828-34.
Molecular Therapy
Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells.
Podsakoff GM, Engel BC, Carbonaro DA, Choi C, Smogorzewska EM, Bauer G, Selander D, Csik S, Wilson K, Betts MR, Koup RA, Nabel GJ, Bishop K, King S, Schmidt M, von Kalle C, Church JA, Kohn DB.
Mol Ther. 2005 Jul;12(1):77-86.
Journal of Virology
Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens.
Wu L, Kong WP, Nabel GJ.
J Virol. 2005 Jul;79(13):8024-31.
Virology
Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus.
Rutigliano JA, Rock MT, Johnson AK, Crowe JE Jr, Graham BS.
Virology. 2005 Jul 5;337(2):335-43.
Nature Medicine
Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.
Jones SM, Feldmann H, Stroher U, Geisbert JB, Fernando L, Grolla A, Klenk HD, Sullivan NJ, Volchkov VE, Fritz EA, Daddario KM, Hensley LE, Jahrling PB, Geisbert TW.
Nat Med. 2005 Jul;11(7):786-90.
Journal of Virology
Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells.
Smed-Sorensen A, Lore K, Vasudevan J, Louder MK, Andersson J, Mascola JR, Spetz AL, Koup RA.
J Virol. 2005 Jul;79(14):8861-9.
Journal of Biological Chemistry
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.
Wooldridge L, van den Berg HA, Glick M, Gostick E, Laugel B, Hutchinson SL, Milicic A, Brenchley JM, Douek DC, Price DA, Sewell AK.
J Biol Chem. 2005 Jul 29;280(30):27491-501.
Virology
Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d.
Koch M, Frazier J, Sodroski J, Wyatt R.
Virology. 2005 Jul 25; [Epub ahead of print]
June
Science
Immunology. Close to the edge: neutralizing the HIV-1 envelope.
Nabel GJ.
Science. 2005 Jun 24;308(5730):1878-9.
Journal of Experimental Medicine
Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells.
Lore K, Smed-Sorensen A, Vasudevan J, Mascola JR, Koup RA.
J Exp Med. 2005 Jun 20;201(12):2023-33.
Journal of Immunology
Immunization with HIV-1 Gag Protein Conjugated to a TLR7/8 Agonist Results in the Generation of HIV-1 Gag-Specific Th1 and CD8+ T Cell Responses.
Wille-Reece U, Wu CY, Flynn BJ, Kedl RM, Seder RA.
J Immunol. 2005 Jun 15;174(12):7676-83.
Clinical Cancer Research
In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins.
Fujiwara H, Melenhorst JJ, El Ouriaghli F, Kajigaya S, Grube M, Sconocchia G, Rezvani K, Price DA, Hensel NF, Douek DC, Barrett AJ.
Clin Cancer Res. 2005 Jun 15;11(12):4495-503.
BMC Immunology
Standardization of cytokine flow cytometry assays.
Maecker HT, Rinfret A, D'Souza P, Darden J, Roig E, Landry C, Hayes P, Birungi J, Anzala O, Garcia M, Harari A, Frank I, Baydo R, Baker M, Holbrook J, Ottinger J, Lamoreaux L, Epling CL, Sinclair E, Suni MA, Punt K, Calarota S, El-Bahi S, Alter G, Maila H, Kuta E, Cox J, Gray C, Altfeld M, Nougarede N, Boyer J, Tussey L, Tobery T, Bredt B, Roederer M, Koup R, Maino VC, Weinhold K, Pantaleo G, Gilmour J, Horton H, Sekaly RP.
BMC Immunol. 2005 Jun 24;6(1):13.
Journal of Immunology
Role for innate IFNs in determining respiratory syncytial virus immunopathology.
Johnson TR, Mertz SE, Gitiban N, Hammond S, Legallo R, Durbin RK, Durbin JE.
J Immunol. 2005 Jun 1;174(11):7234-41.
Bioorganic & Medicinal Chemistry
Synthesis, in vitro, and in vivo characterization of an integrin alpha(v)beta(3)-targeted molecular probe for optical imaging of tumor.
WBurnett CA, Xie J, Quijano J, Shen Z, Hunter F, Bur M, Li KC, Danthi SN.
Bioorg Med Chem. 2005 Jun 1;13(11):3763-71.
May
Journal of Virology
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates.
Santra S, Seaman MS, Xu L, Barouch DH, Lord CI, Lifton MA, Gorgone DA, Beaudry KR, Svehla K, Welcher B, Chakrabarti BK, Huang Y, Yang ZY, Mascola JR, Nabel GJ, Letvin NL.
J Virol. 2005 May;79(10):6516-22.
Vaccine
Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate.
Chakrabarti BK, Ling X, Yang ZY, Montefiori DC, Panet A, Kong WP, Welcher B, Louder MK, Mascola JR, Nabel GJ.
Vaccine. 2005 May 16;23(26):3434-45.
Virology
Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus.
Rutigliano JA, Rock MT, Johnson AK, Crowe JE Jr, Graham BS.
Virology. 2005 May 22 [Epub ahead of print]
Journal of Virology
RhoA signaling is required for respiratory syncytial virus-induced syncytium formation and filamentous virion morphology.
Gower TL, Pastey MK, Peeples ME, Collins PL, McCurdy LH, Hart TK, Guth A, Johnson TR, Graham BS.
J Virol. 2005 May;79(9):5326-36.
Blood
Antigen-specific T cell memory is preserved in children treated for acute lymphoblastic leukemia.
Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM.
Blood. 2005 May 26 [Epub ahead of print]
Proceedings of the National Academy of Sciences
Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans.
Song K, Rabin RL, Hill BJ, De Rosa SC, Perfetto SP, Zhang HH, Foley JF, Reiner JS, Liu J, Mattapallil JJ, Douek DC, Roederer M, Farber JM.
Proc Natl Acad Sci U S A. 2005 May 19; [Epub ahead of print]
Structure
Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Huang CC, Stricher F, Martin L, Decker JM, Majeed S, Barthe P, Hendrickson WA, Robinson J, Roumestand C, Sodroski J, Wyatt R, Shaw GM, Vita C, Kwong PD.
Structure (Camb). 2005 May;13(5):755-68.
Journal of Experimental Medicine
Antigenic conservation and immunogenicity of the HIV coreceptor binding site.
Decker JM, Bibollet-Ruche F, Wei X, Wang S, Levy DN, Wang W, Delaporte E, Peeters M, Derdeyn CA, Allen S, Hunter E, Saag MS, Hoxie JA, Hahn BH, Kwong PD, Robinson JE, Shaw GM.
J Exp Med. 2005 May 2;201(9):1407-19.
Proceedings of the National Academy of Sciences
Resting naive CD4+ T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques.
Nishimura Y, Brown CR, Mattapallil JJ, Igarashi T, Buckler-White A, Lafont BA, Hirsch VM, Roederer M, Martin MA.
Proc Natl Acad Sci U S A. 2005 May 23; [Epub ahead of print]
April
Journal of Virology
Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes.
Seaman MS, Xu L, Beaudry K, Martin KL, Beddall MH, Miura A, Sambor A, Chakrabarti BK, Huang Y, Bailer R, Koup RA, Mascola JR, Nabel GJ, Letvin NL.
J Immunol. 2005 Apr 15;174(8):4753-60.
Journal of Allergy and Clinical Immunology
VRC 004: Safety and Immunogenicity of a Multiclade HIV-1 DNA Vaccine in Healthy Uninfected Adults (VRC-HIVDNA009-00-VP).
Martin JE, Enama ME, Koup RA, Bailer RT, Moodie Z, Roederer M, Nabel GJ, Graham BS.
J Allergy Clin Immunol. 2005 Apr;115(4):892.
Journal of Virology
Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys.
Seaman MS, Santra S, Newberg MH, Philippon V, Manson K, Xu L, Gelman RS, Panicali D, Mascola JR, Nabel GJ, Letvin NL.
J Virol. 2005 Apr;79(8):4580-8.
Journal of Biological Chemistry
Interaction between the CD8 coreceptor and MHC class I stabilizes TCR-antigen complexes at the cell surface.
Wooldridge L, van den Berg HA, Glick M, Gostick E, Laugel B, Hutchinson SL, Milicic A, Brenchley JM, Douek DC, Price DA, Sewell AK.
J Biol Chem. 2005 Apr 18; [Epub ahead of print]
Science
Endosomal Proteolysis of the Ebola Virus Glycoprotein Is Necessary for Infection.
Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM.
Science. 2005 Apr 14; [Epub ahead of print]
March
Journal of Virology
Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys.
Sun Y, Schmitz JE, Acierno PM, Santra S, Subbramanian RA, Barouch DH, Gorgone DA, Lifton MA, Beaudry KR, Manson K, Philippon V, Xu L, Maecker HT, Mascola JR, Panicali D, Nabel GJ, Letvin NL.
J Virol. 2005 Mar;79(5):2956-63.
Journal of Infectious Diseases
Lessons from failure--preparing for future HIV-1 vaccine efficacy trials.
Graham BS, Mascola JR.
J Infect Dis. 2005 Mar 1;191(5):647-9.
Nature
Massive infection and loss of memory CD4(+) T cells in multiple tissues during acute SIV infection.
Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M.
J Infect Dis. 2005 Mar 27; [Epub ahead of print]
Proceedings of the National Academy of Sciences
Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.
Betts MR, Exley B, Price DA, Bansal A, Camacho ZT, Teaberry V, West SM, Ambrozak DR, Tomaras G, Roederer M, Kilby JM, Tartaglia J, Belshe R, Gao F, Douek DC, Weinhold KJ, Koup RA, Goepfert P, Ferrari G.
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4512-7.
American Journal of Transplantation
Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion.
Pearl JP, Parris J, Hale DA, Hoffmann SC, Bernstein WB, McCoy KL, Swanson SJ, Mannon RB, Roederer M, Kirk AD.
Am J Transplant. 2005 Mar;5(3):465-74.
Journal of Virology
Immunologic pressure within class I-restricted cognate human immunodeficiency virus epitopes during highly active antiretroviral therapy.
Casazza JP, Betts MR, Hill BJ, Brenchley JM, Price DA, Douek DC, Koup RA.
J Virol. 2005 Mar;79(6):3653-63.
Journal of Experimental Medicine
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients.
Muraro PA, Douek DC, Packer A, Chung K, Guenaga FJ, Cassiani-Ingoni R, Campbell C, Memon S, Nagle JW, Hakim FT, Gress RE, McFarland HF, Burt RK, Martin R.
J Exp Med. 2005 Mar 7;201(5):805-16.
Blood
Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner.
Seggewiss R, Lore K, Greiner E, Magnusson MK, Price DA, Douek DC, Dunbar CE, Wiestner A.
Blood. 2005 Mar 15;105(6):2473-9.
Vaccine
Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand.
Karnasuta C, Paris RM, Cox JH, Nitayaphan S, Pitisuttithum P, Thongcharoen P, Brown AE, Gurunathan S, Tartaglia J, Heyward WL, McNeil JG, Birx DL, de Souza MS; Thai AIDS Vaccine Evaluation Group, Thailand.
Vaccine. 2005 Mar 31;23(19):2522-9.
February
Nature
Human immunodeficiency virus: refolding the envelope.
Kwong PD.
Nature. 2005 Feb 24;433(7028):815-6.
Virology
Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage.
Pancera M, Wyatt R.
Virology. 2005 Feb 5;332(1):145-56.
January
Proceeding of the National Academy of Sciences
Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses.
Yang ZY, Werner HC, Kong WP, Leung K, Traggiai E, Lanzavecchia A, Nabel GJ
Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):797-801. Epub 2005 Jan 10.
Journal of Virology
Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins.
Mascola JR, Sambor A, Beaudry K, Santra S, Welcher B, Louder MK, Vancott TC, Huang Y, Chakrabarti BK, Kong WP, Yang ZY, Xu L, Montefiori DC, Nabel GJ, Letvin NL.
J Virol. 2005 Jan;79(2):771-9.
Journal of Virology
Comparative immunogenicity of human immunodeficiency virus particles and corresponding polypeptides in a DNA vaccine.
Akahata W, Yang ZY, Nabel GJ.
J Virol. 2005 Jan;79(1):626-31.
Journal of Virology
Ebola virus glycoprotein toxicity is mediated by a dynamin-dependent protein-trafficking pathway.
Sullivan NJ, Peterson M, Yang ZY, Kong WP, Duckers H, Nabel E, Nabel GJ
J Virol. 2005 Jan;79(1):547-53.
Virology
Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.
Grundner C, Li Y, Louder M, Mascola J, Yang X, Sodroski J, Wyatt R.
Virology. 2005 Jan 5;331(1):33-46.
Journal of Biological Chemistry
Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.
Laugel B, Boulter JM, Lissin N, Vuidepot A, Li Y, Gostick E, Crotty LE, Douek DC, Hemelaar J, Price DA, Jakobsen BK, Sewell AK.
J Biol Chem. 2005 Jan 21;280(3):1882-92. Epub 2004 Nov 04.
Journal of Immunology
Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms.
Hashimoto K, Sheller JR, Morrow JD, Collins RD, Goleniewska K, O'Neal J, Zhou W, Ji S, Mitchell DB, Graham BS, Peebles RS Jr.
J Immunol. 2005 Jan 1;174(1):525-32.
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