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Brief Summary

GUIDELINE TITLE

Chronic abdominal pain in children.

BIBLIOGRAPHIC SOURCE(S)

GUIDELINE STATUS

This is the current release of the guideline.

All clinical reports from the American Academy of Pediatrics (AAP) automatically expire 5 years after publication unless reaffirmed, revised, or retired at or before that time.

BRIEF SUMMARY CONTENT

 
RECOMMENDATIONS
 EVIDENCE SUPPORTING THE RECOMMENDATIONS
 IDENTIFYING INFORMATION AND AVAILABILITY
 DISCLAIMER

 Go to the Complete Summary

RECOMMENDATIONS

MAJOR RECOMMENDATIONS

Recommendations

  1. The term "recurrent abdominal pain" as currently used clinically and in the literature should be retired. Functional abdominal pain is the most common cause of chronic abdominal pain. It is a specific diagnosis that needs to be distinguished from anatomic, infectious, inflammatory, or metabolic causes of abdominal pain. Functional abdominal pain may be categorized as one or a combination of: functional dyspepsia, irritable bowel syndrome, abdominal migraine, or functional abdominal pain syndrome (see table below titled "Recommended Clinical Definitions of Long-Lasting Intermittent or Constant Abdominal Pain in Children").
  2. Functional abdominal pain generally can be diagnosed correctly by the primary care clinician in children 4 to 18 years of age with chronic abdominal pain when there are no alarm symptoms or signs, the physical examination is normal, and the stool sample tests are negative for occult blood, without the requirement of additional diagnostic evaluation.
  3. The presence of alarm symptoms or signs, including but not limited to involuntary weight loss, deceleration of linear growth, gastrointestinal blood loss, significant vomiting, chronic severe diarrhea, persistent right upper or right lower quadrant pain, unexplained fever, family history of inflammatory bowel disease, or abnormal or unexplained physical findings, is generally an indication to pursue diagnostic testing for specific anatomic, infectious, inflammatory, or metabolic etiologies on the basis of specific symptoms in an individual case. Significant vomiting includes bilious emesis, protracted vomiting, cyclical vomiting, or a pattern worrisome to the physician. Alarm signs on abdominal examination include localized tenderness in the right upper or right lower quadrants, a localized fullness or mass effect, hepatomegaly, splenomegaly, costovertebral angle tenderness, tenderness over the spine, and perianal abnormalities.
  4. Testing may also be performed to reassure the patient, parent, and physician of the absence of organic disease, particularly if the pain significantly diminishes the quality of life of the patient.
  5. The child with functional abdominal pain is best evaluated and treated in the context of a biopsychosocial model of care. Although psychological factors do not help the clinician distinguish between organic (disease-based) and functional pain, it is important to address these factors in the diagnostic evaluation and management of these children.
  6. Education of the family is an important part of treatment of the child with functional abdominal pain. It is often helpful to summarize the child's symptoms and explain in simple language that although the pain is real, there is most likely no underlying serious or chronic disease. It may be helpful to explain that chronic abdominal pain is a common symptom in children and adolescents, yet few have a disease. Functional abdominal pain can be likened to a headache, a functional disorder experienced at some time by most adults, which very rarely is associated with serious disease. It is important to provide clear and age-appropriate examples of conditions associated with hyperalgesia, such as a healing scar, and manifestations of the interaction between brain and gut, such as the diarrhea or vomiting children may experience during stressful situations (e.g., before school examinations or important sports competitions).
  7. It is recommended that reasonable treatment goals be established, with the main aim being the return to normal function rather than the complete disappearance of pain. Return to school can be encouraged by identifying and addressing obstacles to school attendance.
  8. Medications for functional abdominal pain are best prescribed judiciously as part of a multifaceted, individualized approach to relieve symptoms and disability. It is reasonable to consider the time-limited use of medications that might help to decrease the frequency or severity of symptoms. Treatment might include acid-reduction therapy for pain associated with dyspepsia; antispasmodic agents, smooth muscle relaxants, or low doses of psychotropic agents for pain or nonstimulating laxatives or antidiarrheals for pain associated with altered bowel pattern.
  9. Additional research is needed to fill the large gaps of knowledge on chronic abdominal pain in children.
Recommended Clinical Definitions of Long-Lasting Intermittent or Constant Abdominal Pain in Children
Term Clinical Definition
Chronic abdominal pain Long-lasting intermittent or constant abdominal pain that is functional or organic (disease-based)
Functional abdominal pain Abdominal pain without demonstrable evidence of a pathologic condition, such as an anatomic, metabolic, infectious, inflammatory, or neoplastic disorder; functional abdominal pain may present with symptoms typical of functional dyspepsia, irritable bowel syndrome, abdominal migraine, or functional abdominal pain syndrome.
Functional dyspepsia Functional abdominal pain or discomfort in the upper abdomen
Irritable bowel syndrome Functional abdominal pain associated with alteration in bowel movements
Abdominal migraine Functional abdominal pain with features of migraine (paroxysmal abdominal pain associated with anorexia, nausea, vomiting, or pallor as well as a maternal history of migraine headaches)
Functional abdominal pain syndrome Functional abdominal pain without the characteristics of dyspepsia, irritable bowel syndrome, or abdominal migraine

CLINICAL ALGORITHM(S)

None provided

EVIDENCE SUPPORTING THE RECOMMENDATIONS

TYPE OF EVIDENCE SUPPORTING THE RECOMMENDATIONS

Of the 83 studies for which methodology was reviewed, 46 were case control, 20 were cohort cross section, 10 were cohort follow-up, and 7 were randomized controlled trials (RCTs).

IDENTIFYING INFORMATION AND AVAILABILITY

BIBLIOGRAPHIC SOURCE(S)

ADAPTATION

Not applicable: The guideline was not adapted from another source.

DATE RELEASED

2005 Mar

GUIDELINE DEVELOPER(S)

American Academy of Pediatrics - Medical Specialty Society

SOURCE(S) OF FUNDING

American Academy of Pediatrics

GUIDELINE COMMITTEE

Subcommittee on Chronic Abdominal Pain

COMPOSITION OF GROUP THAT AUTHORED THE GUIDELINE

Subcommittee on Chronic Abdominal Pain: Carlo Di Lorenzo, MD, Co-chairperson; Richard B. Colletti, MD, Co-chairperson; Harold P. Lehmann, MD, PhD; John T. Boyle, MD; William T. Gerson, MD; Jeffrey S. Hyams, MD; Robert H. Squires, Jr, MD; Lynn S. Walker, PhD

Staff: Pamela T. Kanda, MPH

FINANCIAL DISCLOSURES/CONFLICTS OF INTEREST

Not stated

GUIDELINE STATUS

This is the current release of the guideline.

All clinical reports from the American Academy of Pediatrics (AAP) automatically expire 5 years after publication unless reaffirmed, revised, or retired at or before that time.

GUIDELINE AVAILABILITY

Electronic copies: Available from the American Academy of Pediatrics (AAP) Policy Web site.

Print copies: Available from American Academy of Pediatrics, 141 Northwest Point Blvd., P.O. Box 927, Elk Grove Village, IL 60009-0927.

AVAILABILITY OF COMPANION DOCUMENTS

PATIENT RESOURCES

None available

NGC STATUS

This NGC summary was completed by ECRI on March 23, 2005.

COPYRIGHT STATEMENT

This NGC summary is based on the original guideline, which is subject to the guideline developer's copyright restrictions. Please contact the Permissions Editor, American Academy of Pediatrics (AAP), 141 Northwest Point Blvd, Elk Grove Village, IL 60007.

DISCLAIMER

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