Santos SS, Enohata T; International Conference on AIDS (15th : 2004 : Bangkok, Thailand).

Int Conf AIDS. 2004 Jul 11-16; 15: abstract no. ThPeC7395.

Casa da Aids, Hospital das Clinicas, :University of Sao Paulo School of Medicine, Sao Paulo, Brazil

Background: Introduction of HAART resulted in significant increase in life expectance of HIV infected patients. This population is at risk for a variety of vaccine preventable infections. The National Immunization Program from Brazilian Ministry of Health elaborated recommendations for vaccine use in HIV infected people. Notwithstanding, the vaccine coverage reached by this program is unknown. Methods: Cross-sectional study to evaluate the vaccine coverage of HIV infected adults followed at Casa da Aids, Hospital das Clinicas, University of Sao Paulo School of Medicine. Outpatient clinic responsible for attendance of 3,598 HIV infected patients. 368 patients were randomly chosen. Data were collected on age, gender, mode of HIV transmission, CDC classification, antiretrovirals, last CD4 count and HIV viral load, and immunization charts. Every HIV infected patient should be vaccinated against diphtheria/tetanus, pneumococcal pneumonia, influenza, and hepatitis B. MMR and Yellow Fever vaccines are recommended to patients CD4 count higher than 200 or 350 cell/mm[3], depending of epidemiological risk. Sabin vaccine is not recommended for children who contact HIV infected patients, they should receive Salk vaccine. Results: Up to this moment, we have interviewed 105 patients, 75.2% male, mean age 39.9 years (21-70). In relation to mode of HIV transmission: 53.3% MSM, 41.9% heterosexual, 2.9% IDU, 1% transfusional, and 1% accidental. In relation to disease classification: 42.9% A, 20% B, and 37.1% C. Most of patients (88.6%) were taking antiretroviral drugs, 96.8% of them on HAART. Mean CD4 count 434.1 cell/mm[3] (69-1,390). Viral load<400 copies/mL in 59.6% patients. Only 35.2% patients were adequately immunized for diphtheria/tetanus, 54.3% pneumococcus, 27.6% flu, and 78% hepatitis B. Only one patient received MMR vaccine. Two patients received Yellow Fever vaccine despite CD4<200 cell/mm[3]. In relation to polio, 25% of patients contact with Sabin immunized children.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS Vaccines
• Acquired Immunodeficiency Syndrome
• Adult
• Antiretroviral Therapy, Highly Active
• Brazil
• CD4 Lymphocyte Count
• CD4-Positive T-Lymphocytes
• Child
• Cross-Sectional Studies
• HIV Infections
• HIV Seropositivity
• Humans
• Immunization
• Influenza Vaccines
• Male
• Measles-Mumps-Rubella Vaccine
• Tetanus
• Vaccination
• Vaccines
• Viral Load

Other ID:

• GWAIDS0036958

UI: 102281174

From Meeting Abstracts