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UGID:156406     UniGene Hs.162585     Homo sapiens (human)   SLC12A2 Links
Bumetanide-sensitive Na-K-Cl cotransporter (NKCC1) (SLC12A2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_001037.1 solute carrier family 12 (sodium/potassium/chloride transporters), member 2 H. sapiens 100.0 1211
XP_526998.2 PREDICTED: solute carrier family 12 (sodium/potassium/chloride transporters), member 2 P. troglodytes 99.8 1210
XP_001098624.1 PREDICTED: solute carrier family 12 (sodium/potassium/chloride transporters), member 2 isoform 2 M. mulatta 99.8 1209
NP_033220.2 solute carrier family 12, member 2 M. musculus 97.7 1205
NP_001091331.1 Na-K-2Cl cotransporter 1 X. laevis 90.1 1134
NP_001002080.1 solute carrier family 12 (potassium/chloride transporters), member 2 D. rerio 82.0 1130
NP_648572.1 sodium chloride cotransporter 69 CG4357-PA, isoform A D. melanogaster 58.7 1153
NP_001076724.1 Na-K-Cl Cotransporter homolog family member (nkcc-1) C. elegans 55.1 1092

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; brain; prostate; ear; vascular; salivary gland; heart; larynx; pharynx; lymph node; bone marrow; adrenal gland; thyroid; trachea; testis; embryonic tissue; ovary; mammary gland; stomach; uterus; liver; uncharacterized tissue; thymus; lung; eye; parathyroid; muscle; mixed; kidney; cervix; bladder; skin; pancreas; blood; ascites; connective tissue; mouth; placenta; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q23.3
UniSTS entry: Chr 5 STS-N22107
UniSTS entry: Chr 5 SGC35509
UniSTS entry: Chr 5 bac51423S
UniSTS entry: Chr 5 A006Y26
UniSTS entry: Chr Y D10S275
UniSTS entry: Chr 5 SGC32885
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AY280459.1 Homo sapiens bumetanide-sensitive Na-K-Cl cotransporter (SLC12A2) mRNA, complete cds P
NM_001046.2 Homo sapiens solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2), mRNA PA
CR611229.1 full-length cDNA clone CS0DK009YH09 of HeLa cells Cot 25-normalized of Homo sapiens (human)
AB209192.1 Homo sapiens mRNA for solute carrier family 12 (sodium/potassium/chloride transporters), member 2 variant protein P
AK025062.1 Homo sapiens cDNA: FLJ21409 fis, clone COL03924 A
AF439152.1 Homo sapiens sodium-potassium-chloride cotransporter (SLC12A2) mRNA, partial cds, alternatively spliced P
Z36839.1 H.sapiens (xs81) mRNA, 289bp
M18217.1 Human DNA of undetermined origin found 5' to NCA mRNA
U30246.1 Human bumetanide-sensitive Na-K-Cl cotransporter (NKCC1) mRNA, complete cds P

EST sequences (207)

AI014857.1 Clone IMAGE:1622097 embryonic tissue 3' read A
AI078667.1 Clone IMAGE:1667919 parathyroid 3' read A
AI124709.1 Clone IMAGE:1540026 brain 3' read P
BX098657.1 Clone IMAGp998L215321_;_IMAGE:2155172 intestine A
BX106574.1 Clone IMAGp998M234417 testis 5' read P
AI187969.1 Clone IMAGE:1738558 testis 3' read A
CB146321.1 Clone L16HLK3-26-D07 liver 5' read P
CB158589.1 Clone L18POOL1n1-12-A05 liver 5' read A
CB113574.1 Clone L6ChoCK0-22-F11 liver 5' read
CB137340.1 Clone L6ChoCK0-24-D09 liver 5' read P
CB139845.1 Clone L9SNU354-3-F05 liver 5' read
AI358155.1 Clone IMAGE:1991504 uterus 3' read A
AI380427.1 Clone IMAGE:2107123 uncharacterized tissue 3' read
AI469517.1 Clone IMAGE:2156474 intestine 3' read
AI471561.1 Clone IMAGE:2155172 intestine 3' read A
AI493213.1 Clone IMAGE:2131946 stomach 3' read A
AI743782.1 Clone IMAGE:2368870 mixed 3' read A
AI744509.1 Clone IMAGE:2364557 mixed 3' read A
AL079464.1 Clone DKFZp434C0325 testis 5' read
AL079748.1 Clone DKFZp434I2430 testis 5' read P
AI866005.1 Clone IMAGE:2425803 uterus 3' read
CD105170.1 Clone IMAGE:30369903 mixed 5' read
BX352495.2 Clone CS0DK009YH09 cervix 3' read A
BX442124.2 Clone CS0DF026YC14 brain 5' read
BX404783.2 Clone CS0DF026YC14 brain 5' read P
BX451585.2 Clone CS0DF026YC14 brain 5' read P
BX451586.1 Clone CS0DF026YC14 brain 5' read P
AW009797.1 Clone IMAGE:2504947 intestine 3' read A
AW014143.1 Clone IMAGE:2709453 uncharacterized tissue 3' read A
AW021256.1 Clone IMAGE:2484037 ear 5' read A
BX470908.1 Clone DKFZp686F09123 muscle 5' read P
AW023186.1 Clone IMAGE:2486907 ear 5' read A
CD653679.1 Clone IMAGE:30422487 embryonic tissue 5' read P
CD655113.1 Clone IMAGE:30425556 embryonic tissue 5' read P
BX500796.1 Clone DKFZp779D2259 liver 5' read
BX505900.1 Clone DKFZp686P09212 muscle 5' read
BX506078.1 Clone DKFZp686E07221 muscle 5' read
CD704859.1 pharynx
CD722035.1 Clone oj04f09 eye 5' read
AW104671.1 Clone IMAGE:2597695 ovary 3' read A
AW263313.1 Clone IMAGE:2757464 brain 3' read A
AW361701.1 intestine P
AW375533.1 intestine P
AW390000.1 stomach
AW390027.1 stomach
AW391787.1 stomach P
AW391788.1 stomach P
AW391814.1 stomach P
AW391823.1 stomach P
AW471120.1 Clone IMAGE:2799501 intestine 3' read A
AW571545.1 Clone IMAGE:2839241 uterus 3' read
AW753646.1 intestine
AW812190.1 stomach P
BX951180.1 Clone DKFZp781H0810 uncharacterized tissue 5' read
AW841014.1 intestine
AW845556.1 intestine
AW849350.1 intestine P
AW849478.1 intestine P
AW849655.1 intestine P
AW850543.1 intestine P
AW850545.1 intestine P
AW850557.1 intestine P
AW850618.1 intestine P
AW850621.1 intestine P
AW859514.1 intestine P
AW937878.1 kidney P
AW952223.1 uncharacterized tissue A
AW954352.1 uncharacterized tissue A
CN272098.1 embryonic tissue 5' read P
CN272097.1 embryonic tissue 5' read P
CN274997.1 embryonic tissue 5' read
AW956299.1 uncharacterized tissue A
CN360907.1 embryonic tissue 5' read
CN360908.1 embryonic tissue 5' read
BE084576.1 mammary gland P
BE145138.1 mouth
CR737761.1 Clone IMAGp998C044503 mixed 5' read P
BP203169.1 Clone CAE03447 vascular 5' read P
BP236162.1 Clone HCR06971 vascular 5' read P
BP327886.1 Clone PRS08355 prostate 5' read P
BP334286.1 Clone SLV06187 salivary gland 5' read P
BP258252.1 Clone HRT03021 heart 5' read P
H26319.1 Clone IMAGE:161813 mammary gland 3' read A
CV420076.1 intestine
CV575738.1 Clone oe39g12 eye 5' read P
BE501893.1 Clone IMAGE:3185034 kidney 3' read A
H46617.1 Clone IMAGE:187921 mammary gland 5' read
BE719783.1 larynx
BE720527.1 larynx P
BE814282.1 mammary gland
BE834025.1 ovary
BE876334.1 Clone IMAGE:3889140 lung 5' read P
BE859064.1 Clone IMAGE:3309125 prostate 3' read
BE927927.1 intestine
BE932769.1 larynx
BP417851.1 Clone HIE00907r intestine 3' read
BP418224.1 Clone HIE01304r intestine 3' read
BP419690.1 Clone HIE02942r intestine 3' read
BP423363.1 Clone HIE06905r intestine 3' read
BF000373.1 Clone IMAGE:3317198 intestine 3' read A
AV708692.2 Clone ADCALG05 adrenal gland 5' read
AV757255.1 Clone BMFAFH05 bone marrow 5' read
DR421672.1 Clone nav02a02 eye 5' read
DR421732.1 Clone nav02g07 eye 5' read
AU133142.1 Clone NT2RP4001386 testis 5' read P
AA769199.1 Clone IMAGE:1289834 lymph node 3' read A
DN915633.1 Clone MCF7_RNA_L_20_H13 mammary gland
DA210303.1 Clone BRAWH2018366 brain 5' read
DA292084.1 Clone BRHIP2003869 brain 5' read P
DA215702.1 Clone BRAWH3006122 brain 5' read P
BF695274.1 Clone IMAGE:4244788 muscle 5' read
DA112906.1 Clone BRACE3030947 brain 5' read P
BF701470.1 Clone IMAGE:4282890 brain 5' read
DA343498.1 Clone BRSSN2003618 brain 5' read
BF727172.1 Clone by17g09 eye 5' read P
DA417684.1 Clone BRTHA3027267 brain 5' read P
DA692300.1 Clone NT2NE2012192 5' read P
H65116.1 Clone IMAGE:238612 pharynx 3' read
H65168.1 Clone IMAGE:238612 pharynx 5' read
DA412867.1 Clone BRTHA3020585 brain 5' read
AV720958.1 Clone HTBARG09 brain 5' read P
BF061256.1 Clone IMAGE:3251119 thyroid 3' read PA
BF061266.1 Clone IMAGE:3251178 thyroid 3' read A
BF063777.1 Clone IMAGE:3324141 intestine 3' read A
DA460053.1 Clone CTONG3006720 mouth 5' read P
AU151037.1 Clone NT2RP2004247 testis 3' read
DB002855.1 Clone TBAES2005138 mammary gland 5' read
DA734017.1 Clone NT2RP2004247 testis 5' read
DB020211.1 Clone TESTI2000307 testis 5' read P
DA872342.1 Clone PROST2009201 prostate 5' read P
DB218397.1 Clone TRACH3008125 trachea 5' read
DB231206.1 Clone TRACH3024727 trachea 5' read P
DB225068.1 Clone TRACH3016844 trachea 5' read P
DB233707.1 Clone TRACH3028042 trachea 5' read P
DB083311.1 Clone TESTI4029897 testis 5' read P
DB050295.1 Clone TESTI2039812 testis 5' read P
DB234759.1 Clone TRACH3029476 trachea 5' read P
DB234973.1 Clone TRACH3029768 trachea 5' read P
DB241343.1 Clone TRACH3038113 trachea 5' read P
DB197012.1 Clone TRACH2003962 trachea 5' read
DB197419.1 Clone TRACH2004652 trachea 5' read P
DB236393.1 Clone TRACH3031672 trachea 5' read P
DB348635.1 Clone TRACH2019082 trachea 3' read
DB349668.1 Clone TRACH3017576 trachea 3' read A
DB127049.1 Clone THYMU2036918 thymus 5' read P
DB167431.1 Clone TKIDN2000880 kidney 5' read
DB370116.1 Clone NT2RP4001386 testis 3' read
DB102407.1 Clone THYMU2001601 thymus 5' read
DB097944.1 Clone TESTI4049326 testis 5' read P
DB217363.1 Clone TRACH3006718 trachea 5' read P
BF765895.1 intestine P
BG034886.1 Clone IMAGE:4413323 liver 5' read
BF884820.1 lung P
N22107.1 Clone IMAGE:253982 ear 3' read A
DB545836.1 Clone H023074H02 brain 3' read A
DB576888.1 Clone H033095O09 brain 3' read P
DB547501.1 Clone H023080I11 brain 3' read A
DB520154.1 Clone H013066J12 testis 3' read
DB505604.1 Clone H033095O09 brain 5' read P
DB523270.1 Clone H013079B18 testis 3' read
BG254535.1 Clone IMAGE:4476854 prostate 5' read
BG260706.1 Clone IMAGE:4480195 bladder 5' read
DB454744.1 Clone H013066J12 testis 5' read P
DB477181.1 Clone H023074H02 brain 5' read P
DB478837.1 Clone H023080I11 brain 5' read P
DB515528.1 Clone H013046F04 testis 3' read
BG287050.1 Clone IMAGE:4499914 bladder 5' read P
BG403285.1 Clone IMAGE:4526482 bladder 5' read
BG545721.1 Clone IMAGE:4700902 lung 5' read
BG529061.1 Clone IMAGE:4713349 prostate 5' read P
BG619241.1 Clone IMAGE:4730244 placenta 5' read P
BG675557.1 Clone IMAGE:4747164 skin 5' read
BG676095.1 Clone IMAGE:4747555 skin 5' read
N56950.1 Clone IMAGE:280090 brain 3' read A
U47707.1 Clone xs420 pancreas
BG720175.1 Clone IMAGE:4824556 testis 5' read P
AU186081.1 Clone M00059-011 blood
BI493113.1 Clone IMAGE:2540730 ear 5' read A
BI495973.1 Clone IMAGE:2540045 ear 5' read A
BM663073.1 Clone UI-E-CI0-aaf-f-11-0-UI eye 3' read PA
BM802981.1 Clone IMAGE:5560357 intestine 5' read P
BM788095.1 Clone S10SNU1-21-G06 ascites 5' read
BM790529.1 Clone S21SNU520-11-A06 stomach 5' read
BM978607.1 Clone UI-CF-DU1-adq-m-11-0-UI lung 3' read A
BQ001672.1 Clone IMAGE:5893169 connective tissue 3' read A
BQ009463.1 Clone IMAGE:5834035 connective tissue 3' read PA
BQ021600.1 Clone IMAGE:5828271 connective tissue 3' read PA
BQ318631.1 intestine
BQ320000.1 intestine
BQ440563.1 Clone IMAGE:6157583 skin 5' read P
AA102264.1 Clone IMAGE:511011 intestine 3' read A
AA129551.1 Clone IMAGE:564801 lung 5' read
AA136565.1 Clone IMAGE:564801 lung 3' read A
BM955817.1 Clone HEV#2862 tonsil
AA255695.1 Clone IMAGE:685801 lymph node 5' read P
AA262080.1 Clone IMAGE:685801 lymph node 3' read
CA335769.1 Clone IMAGE:5606992 embryonic tissue 5' read
CA312756.1 Clone UI-CF-FN0-afl-m-22-0-UI lung 3' read PA
CA314642.1 Clone UI-CF-FN0-afh-h-19-0-UI lung 3' read PA
AA425619.1 Clone IMAGE:773337 embryonic tissue 5' read
AA501971.1 Clone IMAGE:956397 prostate A
AA581177.1 Clone IMAGE:802548 intestine 5' read A
T25163.1 Clone 34G6 intestine P
AA618510.1 Clone IMAGE:1117828 prostate 3' read
AA627578.1 Clone IMAGE:1146773 intestine 3' read A
AA639406.1 Clone IMAGE:1159466 intestine 3' read
AA639599.1 Clone IMAGE:1158883 intestine 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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