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meloxicam - Substance Summary (SID 10369)

structure in first source


Drug and Chemical Information: (Total:1)         

Medication Information

Meloxicam, an oxicam derivative, is a member of the enolic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). Each pale yellow to yellow tablet contains 7.5 mg or 15 mg meloxicam for oral administration. Meloxicam is chemically
DescriptionClinical PharmacologyIndication & Usage
ContraindicationsWarningsPrecautions
Adverse ReactionsOverdosageDosage & Administration
How SuppliedSupplemental Patient MaterialBoxed Warning














Pharmacological Action

Anti-Inflammatory Agents, Non-Steroidal - Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and ...

Cyclooxygenase Inhibitors - Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme ...


  Pharmacological Classification
Chemical Actions and Uses
      Pharmacologic Actions
            Molecular Mechanisms of Pharmacological Action
                  Enzyme Inhibitors
                        Cyclooxygenase Inhibitors
            Physiological Effects of Drugs
                  Peripheral Nervous System Agents
                        Sensory System Agents
                              Analgesics
                                    Analgesics, Non-Narcotic
                                          Anti-Inflammatory Agents, Non-Steroidal
                                                Cyclooxygenase Inhibitors
            Therapeutic Uses
                  Anti-Inflammatory Agents
                        Anti-Inflammatory Agents, Non-Steroidal
                              Cyclooxygenase Inhibitors
                  Antirheumatic Agents
                        Anti-Inflammatory Agents, Non-Steroidal


Literature

Literature Keyword Mining Tool



Data Source:   

Depositor: KEGG
External ID: C08169

Depositor-Supplied Synonyms: (Total: 3)
Sort:
meloxicam
C08169
71125-38-7


Properties Computed from Structure:
Molecular Weight351.40072 [g/mol]
Molecular FormulaC14H13N3O4S2
XLogP33.4
H-Bond Donor2
H-Bond Acceptor7
Rotatable Bond Count2
Tautomer Count8
Exact Mass351.034747
MonoIsotopic Mass351.034747
Topological Polar Surface Area99.6
Heavy Atom Count23
Formal Charge0
Complexity628
Isotope Atom Count0
Defined Atom StereoCenter Count0
Undefined Atom StereoCenter Count0
Defined Bond StereoCenter Count1
Undefined Bond StereoCenter Count0
Covalently-Bonded Unit Count1


Descriptors Computed from Structure:
IUPAC Name: (3E)-3-[hydroxy-[(5-methyl-1,
3-thiazol-2-yl)amino]methylidene]-2-methyl-1,
1-dioxobenzo[e]thiazin-4-one
Canonical SMILES: CC1=CN=C(S1)NC(=C2C(=O)C3=CC=CC=C3S(=O)(=O)N2C)O
Isomeric SMILES: CC1=CN=C(S1)N/C(=C\2/C(=O)C3=CC=CC=C3S(=O)(=O)N2C)/O
InChI: InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10
(9)23(20,21)17(11)2/h3-7,19H,1-2H3,(H,15,16)/b13-11+

InChIKey: DWMREKMVXIFPFM-ACCUITESSA-N


Substance Information:
SID 10369   
Deposit Date: 2005-06-24
Modify Date: 2008-09-10

CID 5281106   
Create Date: 2005-06-24

Related Substances:
Same: 20 Links
Same, Connectivity: 52 Links
Same, Stereochemistry: 22 Links
Same, Isotopes: 48 Links
Same, Any Tautomers: 56 Links

Similar Substances: 133 Links


Depositor-Supplied Comments:
CAS: 71125-38-7
Same as: D00969

     
Compound Displayed

2D

3D

Compound ID5281106
Molecular Weight351.40072 [g/mol]
Molecular FormulaC14H13N3O4S2
XLogP33.4
H-Bond Donor2
H-Bond Acceptor7


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