Recent Publications

Greene EC, Mizuuchi K. Dynamics of a protein polymer: the assembly and disassembly pathways of the MuB transposition target complex. EMBO J. 21, 1477-1486, 2002

Mizuuchi M, Mizuuchi K. Conformational isomerization in phage Mu transpososome assembly: effects of the transpositional enhancer and of MuB. EMBO J. 20, 6927-6935, 2001

Zheng RL, Ghirlando R, Lee MS, et al. Barrier-to-autointegration factor (BAF) bridges DNA in a discrete, higher-order nucleoprotein complex. Proc. Natl. Acad. Sci. USA 97, 8997, 2000

Kennedy AK, Haniford DB, Mizuuchi K. Single active site catalysis of the successive phosphoryl transfer steps by DNA transposases: Insights from phosphorothioate stereoselectivity. Cell 101, 295-305, 2000

Mizuuchi K, Nobbs TJ, Halford SE, et al. A new method for determining the stereochemistry of DNA cleavage reactions: Application to the SfiI and HpaII restriction endonucleases and to the MuA transposase. Biochemistry 38,: 4640-4648, 1999

Wei SQ, Mizuuchi K, Craigie R. Footprints on the viral DNA ends in Moloney murine leukemia virus preintegration complexes reflect a specific association with integrase. Proc. Natl. Acad. Sci. USA 95, 10535-10540 SEP 1 1998

Wei SQ, Mizuuchi K, Craigie R
A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration
EMBO J. 16, 7511-7520, 1997

Mizuuchi, K. Polynucleotidyl Transfer Reactions in Site-Specific DNA Recombination. Genes to Cells 2, 1-12, 1997.
Wei, S.-Q., Mizuuchi, K. and Craigie, R. A Large Nucleoprotein Assembly at the Ends of the Viral DNA Mediates Retroviral DNA Integration. EMBO J 16, 7511-7520, 1997.

Clubb, R. T., Schumacher, S., Mizuuchi, K., Gronenborn, A. M. and Clore, G. M. Solution Structure of the Ig Subdomain of the Mu end DNA Binding Domain of Mu Phage Transposase. J Mol Biol 273, 19-25, 1997.

Schumacher, S., Clubb, R. T., Cai, M., Mizuuchi, K., Clore, M. and Gronenborn, A. Solution Structure of the Mu End DNA Binding Ib Subdomain of Phage Mu Transposase: Modular DNA recognition by two tethered domains. EMBO J 16, 7532-7541, 1997.

Yang, W. and Mizuuchi, K. Site-specific Recombination in Plane View. Structure 15, 1401-1406, 1997.

Clubb, R. T., Mizuuchi, M., Huth, J. R., Omichinski, J.G., Savilahti, H., Mizuuchi, K., Clore, G. M. and Gronenborn, A. M. The Wing of the Enhancer-binding Domain of Mu Phage Transposase Is Flexible and Is Essential for Efficient Transposition. Proc. Natl. Acad. Sci. USA 93, 1146-1150, 1996.

van Gent, D. C., Mizuuchi, K. and Gellart, M. Similarities between Initiation of V(D)J Recombination and Retroviral Integration . Science 271, 1592-1594, 1996.

Savilahti, H. and Mizuuchi, K. Mu Transpositional Recombination: Donor DNA Cleavage and Strand Transfer in trans by the Mu Transposase. Cell 85, 271-280, 1996.

Rice, P. A., Yang, S., Mizuuchi, K. and Nash, H. Crystal Structure of an IHF-DNA Complex: A Protein-Induced DNA U-Rurn. Cell 87, 1295-1306, 1996.

Rice, P. A. and Mizuuchi, K. Structure of the Bacteriophage Mu Transposase Core: A Common Structural Motif for DNA Transposition and Retroviral Integration. Cell 82, 209-220, 1995.

Savilahti, H., Rice, P. A. and Mizuuchi, K. The Phage Mu Transpososome Core: DNA Requirements for Assembly and Function. EMBO J. 14, 4893-4903, 1995.

Mizuuchi, M., Baker, T. A. and Mizuuchi, K. Assembly of Phage Mu Transpososomes: Cooperative Transitions Assisted by Protein and DNA Scaffolds. Cell 83, 375-385, 1995.

 

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Last updated, August 12th, 2002

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