Cerebral Microcirculation Unit - Division of Intramural Research

S. D. Keilholz, A. C. Silva, M. Raman, H. Merkle, A. P. Koretsky
BOLD and CBV-Weighted Functional Magnetic Resonance Imaging of the Rat Somatosensory System - Magnetic Resonance in Medicine  55(2) 316–324 2006

I. Aoki, Y. Takahashi, K.-H. Chuang, A. C. Silva, T. Igarashi, C. Tanaka, R. W. Childs, A. P. Koretsky
Cell labeling for magnetic resonance imaging with the T1 agent manganese chloride - NMR in Biomedicine  19(1) 50-59 2006

J. H. Lee, A. C. Silva, H. Merkle, A. P. Koretsky
Manganese-enhanced magnetic resonance imaging of mouse brain after systemic administration of MnCl2: dose-dependent and temporal evolution of T1 contrast - Magnetic Resonance in Medicine  53(3) 640-648 2005

J. A. de Zwart, A. C. Silva, P. van Gelderen, P. Kellman, M. Fukunaga, R. Chu, A. P. Koretsky, J. A. Frank, J. H. Duyn
Temporal dynamics of the BOLD fMRI impulse response - Neuroimage  24(3) 667-677 2005

Chen Z, Silva AC, Yang J, Shen J.
Elevated endogenous GABA level correlates with decreased fMRI signals in the rat brain during acute inhibition of GABA transaminase - J Neurosci Res.  79(3) 383-391 2005

A. C. Silva
Perfusion-based fMRI: insights from animal models - Journal of Magnetic Resonance Imaging  22(6) 745-750 2005

A. C. Silva, J. H. Lee, I. Aoki, and A. P. Koretsky
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI): Methodological and Practical Considerations - NMR in Biomedicine  17(8) 532-534 2004

A. P. Koretsky and A. C. Silva
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) - NMR in Biomedicine  17(8) 527-531 2004

S. Keilholz, A. C. Silva, M. Raman, H. Merkle, and A. P. Koretsky
Functional MRI of the Rodent Somatosensory Pathway Using Multi-slice Echo Planar Imaging - Magn. Reson. Med  52(1) 89-99 2004

Aoki I, Wu YJ, Silva AC, Lynch RM, Koretsky AP.
In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI. - Neuroimage  22(3) 1046-1059 2004

Hinds KA, Hill JM, Shapiro EM, Laukkanen MO, Silva AC, Combs CA, Varney TR, Balaban RS, Koretsky AP, Dunbar CE.
Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. - Blood  102(3) 867-872 2003

C. Grabill, A. C. Silva, S. S. Smith, A.P. Koretsky and T. A. Rouault
MRI detection of iron distribution and associated neuronal pathology in iron regulatory protein-2 knockout mice - Brain Res  971 (1) 95-106  2003

Lee SP, Silva AC, Kim SG.
Comparison of diffusion-weighted high-resolution CBF and spin-echo BOLD fMRI at 9.4 T. - Magn Reson Med  47(4) 736-741 2002

A. C. Silva and A. P. Koretsky
Laminar specificity of fMRI onset times during somatosensory stimulation in rat - Proc. Natl. Acad. Sci.  99 (23) 15182-15187  2002

Aoki I, Tanaka C, Takegami T, Ebisu T, Umeda M, Fukunaga M, Fukuda K, Silva AC, Koretsky AP, Naruse S.
Dynamic activity-induced manganese-dependent contrast magnetic resonance imaging (DAIM MRI). - Magn Reson Med.  48(6) 927-933 2002

A. C. Silva, S.-G. Kim and M. Garwood
Imaging Blood Flow in Brain Tumors Using Arterial Spin Labeling - Magn. Reson. Med  44(2) 169-173  2000

T. Duong, A. C. Silva, S.-P. Lee, and S.-G. Kim
Functional MRI of calcium-dependent synaptic activity: cross correlation with CBF and BOLD measurements - Magn. Reson. Med  43(3) 383-392 2000

A. C. Silva, S.-P. Lee, C. Iadecola and S.-G. Kim
Early temporal characteristics of CBF and deoxyhemoglobin changes during somatosensory stimulation - J. Cereb. Blood Flow Metab  20(1) 201-206 2000

Lee SP, Silva AC, Ugurbil K, Kim SG.
Diffusion-weighted spin-echo fMRI at 9.4 T: microvascular/tissue contribution to BOLD signal changes. - Magn Reson Med.   42(5) 919-928 1999

A. C. Silva, S.-P. Lee, G. Yang, C. Iadecola and S.-G. Kim
Simultaneous BOLD and CBF based functional MRI during forepaw stimulation in rat. - J. Cereb. Blood Flow Metab  19(8) 871-879 1999

A. C. Silva and S.-G. Kim
Pseudo-continuous arterial spin labeling technique for measuring CBF dynamics with high temporal resolution - Magn. Reson. Med  43(2) 425-429 1999

Barbier EL, Silva AC, Kim HJ, Williams DS, Koretsky AP.
Perfusion analysis using dynamic arterial spin labeling (DASL). - Magn Reson Med  41(2) 299-308 1999

E. L. Barbier, A. C. Silva, H. J. Kim, D. S. Williams and A. P. Koretsky
Perfusion analysis using dynamic arterial spin labeling (DASL) - Magn. Reson. Med  41 299-308 1999

Forman SD, Silva AC, Dedousis N, Barbier EL, Fernstrom JD, Koretsky AP.
Simultaneous glutamate and perfusion fMRI responses to regional brain stimulation. - J Cereb Blood Flow Metab  18(10) 1064-1070 1998

A. C. Silva, E. L. Barbier, I. J. Lowe, and A. P. Koretsky
Radial Echo-Planar Imaging (rEPI) - J. Magn. Reson. Med  135 242-247 1998

R. G. Pautler, A. C. Silva and A. P. Koretsky
In vivo neuronal tract tracing using manganese enhanced magnetic resonance imaging - Magn. Reson. Med.  40 740-748 1998

Silva AC, Zhang W, Williams DS, Koretsky AP.
Estimation of water extraction fractions in rat brain using magnetic resonance measurement of perfusion with arterial spin labeling. - Magn Reson Med  37(1) 58-68 1997

Silva AC, Williams DS, Koretsky AP.
Evidence for the exchange of arterial spin-labeled water with tissue water in rat brain from diffusion-sensitized  - Magn Reson Med  38(2) 232-237 1997

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