Publications |
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Protective efficacy of a MEQ deleted BAC clone of Marek's disease virus
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Silva, R.F., Lee, L.F., Heidari, M., Dunn, J.R. 2008. Protective efficacy of a MEQ deleted BAC clone of Marek's disease virus [abstract]. American Veterinary Medical Association Convention Notes. 145th AVMA Annual Convention, July 19-22, 2008, New Orleans, LA. 2008 CD-ROM.
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Molecular analysis of reticuloendotheliosis virus isolates obtained from chickens, turkeys and prairie chickens located in different regions in the United States
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Fadly, A.M., Mays, J.K., Silva, R.F. 2008. Molecular analysis of reticuloendotheliosis virus isolates obtained from chickens, turkeys and prairie chickens located in different regions in the United States [abstract]. American Veterinary Medical Association Convention Notes. 145th AVMA Annual Convention, July 19-22, 2008, New Orleans, LA. 2008 CD-ROM.
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Biological and molecular characterization of a reticuloendotheliosis virus isolated from turkeys with lymphomas
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Fadly, A., Mays, J., Lee, L., Silva, R., Crespo, R., Woolcock, P. 2008. Biological and molecular characterization of a reticuloendotheliosis virus isolated from turkeys with lymphomas. German Branch of the World Veterinary Poultry Association/Veterinary Medical Society. 7th International Symposium on Turkey Diseases, June 19-21, 2008, Berlin, Germany. p. 231-235.
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Survey of endogenous virus and TVB* receptor status of commercial chicken stocks supplying specific-pathogen-free eggs
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Hunt, Henry D., Fadly, Aly M., Silva, Robert F., Zhang, Huanmin. 2008. Survey of endogenous virus and TVB* receptor status of commercial chicken stocks supplying specific-pathogen-free eggs. Avian Diseases. 52(3):433-440.
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Deletion of the Marek's disease virus UL41 gene (vhs) has no measurable effect on latency or pathogenesis
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Gimeno, I.M., Silva, R.F. 2008. Deletion of the Marek's disease virus UL41 gene (vhs) has no measurable effect on latency or pathogenesis. Virus Genes. 36:499-507.
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Frequency of multiple serotype 1 Marek's disease virus strains in feather follicle epithelium and tumor cells following superinfection
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Dunn, J.R., Witter, R.L., Silva, R.F., Lee, L.F. 2008. Frequency of multiple serotype 1 Marek's disease virus strains in feather follicle epithelium and tumor cells following superinfection [abstract]. American Veterinary Medical Association Convention Notes. 145th AVMA Annual Convention, July 19-22, 2008, New Orleans, LA. 2008 CD-ROM.
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Recombinant Marek's disease virus (MDV) lacking Meq oncogene confers protection against challenge with a very virulent plus strain of MDV
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Lee, L.F., Lupiani, B., Silva, R.F., Kung, H., Reddy, S.M. 2008. Recombinant Marek's disease virus (MDV) lacking Meq oncogene confers protection against challenge with a very virulent plus strain of MDV. Vaccine. 26:1887-1892.
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Transcriptional profiling of Marek's disease virus genes during cytolytic and latent infection
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Heidari, M., Huebner, M., Kireev, D., Silva, R.F. 2008. Transcriptional profiling of Marek's disease virus genes during cytolytic and latent infection. Virus Genes. 36:383-392.
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Load of challenge Marek's disease virus DNA in blood as a criterion for early diagnosis of Marek's disease tumors
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- (05-Dec-07)
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Quantitative evaluation of viral fitness due to a single nucleotide polymorphism in the Marek's disease virus UL 41 gene via an in vitro competition assay
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Mao, W., Niikura, M., Silva, R.F., Cheng, H.H. 2008. Quantitative evaluation of viral fitness due to a single nucleotide polymorphism in the Marek's disease virus UL41 gene via an in vitro competition assay. Journal of Virological Methods. 148:125-131.
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Creation of diversity in the animal virus world by inter-species and intra-species recombinations: lessons learned from poultry viruses
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Davidson, I., Silva, R.F. 2008. Creation of diversity in the animal virus world by inter-species and intraspecies recombinations: lessons learned from poultry viruses. Virus Genes. 36(1):1-9.
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The effect of vaccination on Marek's disease virus shedding
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Silva, R.F., El-Gohary, A., Dunn, J.R. 2007. The effect of vaccination on Marek's disease virus shedding [abstract]. American Association of Avian Pathologists/American Veterinary Medical Association Abstract. p. 39.
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Overview of developments in the last 10-15 years in recombinant vaccines
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Silva, R.F. 2007. Overview of developments in the last 10-15 years in recombinant vaccines. American Association of Avian Pathologists. p. 28-30.
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Use of molecularly cloned avian leukosis virus to study antigenic variation following infection of meat-type chickens
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Fadly, A.M., Mays, J.K., Silva, R.F., Hunt, H.D. 2007. Use of molecularly cloned avian leukosis virus to study antigenic variation following infection of meat-type chickens [abstract]. American Association of Avian Pathologists/American Veterinary Medical Association Abstract. p. 37.
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A comparison between Marek's disease virus production in feather pulp versus feather follicle epithelium (FFE)
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Dunn, J.R., Finlay, J.B., Witter, R.L., Silva, R.F. 2007. A comparison between Marek's disease virus production in feather pulp versus feather follicle epithelium (FFE) [abstract]. American Association of Avian Pathologists/American Veterinary Medical Association Abstract. p. 40.
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Global gene expression profiling of Marek's disease virus during cytolytic and latency infection
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Heidari, M., Huebner, M., Silva, R.F. 2007. Global gene expression profiling of Marek's disease virus during cytolytic and latency infection [abstract]. Herpesvirus International Workshop. Paper No. 1.55.
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Vaccine development using recombinant DNA technology
- (Review Article)
- (09-Jul-07)
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Characterization of reticuloendotheliosis virus isolates obtained from chickens, turkeys and prairie chickens in the United States
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Fadly, A.M., Mays, J.K., Silva, R.F., Lee, L.F. 2007. Characterization of reticuloendotheliosis virus isolates obtained from chickens, turkeys and prairie chickens in the United States [abstract]. 2007 Beijing 15th Congress World Veterinary Poultry Association Abstract Book. p. 208.
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Characterization of LORF11, a unique gene common to the three Marek's disease virus serotypes
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Lee, L.F., Silva, R.F., Cui, X., Zhang, H., Heidari, M., Reddy, S. 2007. Characterization of LORF11, a unique gene common to the three Marek's disease virus serotypes. Avian Diseases. 51:851-857.
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Sequence determination of variable regions within the genomes of Gallid herpesvirus-2 pathotypes
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Spatz, S.J., Silva, R.F. 2007. Sequence determination of variable regions within the genomes of Gallid herpesvirus-2 pathotypes. Archives of Virology. Available: http://www.springerlink.com/content/ku4064776312w861/.
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MDV-induced skin leukosis in scaleless chickens: tumor development in the absence of feather follicles
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Heidari, M., Fitzgerald, S.D., Zhang, H.M., Silva, R.F., Lee, L.F., Dunn, J.R. 2007. MDV-induced skin leukosis in scaleless chickens: tumor development in the absence of feather follicles. Avian Diseases. 51(3):713-718.
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Development of a polymerase chain reaction to differentiate avian leukosis virus (ALV) subgroups: detection of an ALV contaminate in a commercial Marek's disease vaccine
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Silva, R.F., Fadly, A.M., Taylor, S.P. 2007. Development of a polymerase chain reaction to differentiate avian leukosis virus (ALV) subgroups: detection of an ALV contaminate in a commercial Marek's disease vaccine. Avian Diseases. 51(3):663-667.
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Marek's disease virus molecular biology, oncogenesis and immunoprophylaxis
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Lee, L.F., Silva, R.F. 2006. Marek's disease virus molecular biology, oncogenesis and immunoprophylaxis. In: Poultry Health Conference Proceedings. 13th Conference of Chinese Avian Pathologists, October 15-19, 2006, Changsha, China. p. 47-49.
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Role of Ul13 in Generating Cell-Free Mdv
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Silva, R.F., Lee, L.F., Heidari, M., Gimeno, I.M., Spatz, S.J., Zelepsky, J. 2006. The role of UL13 in generating cell-free MDV [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 28.
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Pathogenesis of MDV in the eye: neoplasia or autoimmunity?
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Gimeno, I., Silva, R.F. 2006. Pathogenesis of MDV in the eye: neoplasia or autoimmunity? 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 16.
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Current Status of Recombinant Marek's Disease Vaccines for Control of Future Outbreaks
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Lee, L.F., Silva, R.F., Reddy, S. 2006. Current status of recombinant Marek's disease vaccines for control of future outbreaks [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 43.
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Infectious Bacterial Artificial Chromosome Clones of Marek's Disease Virus Possessing the Complete Viral Genome Derived from Md5 Cosmid Clones
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Niikura, M., Dodgson, J., Silva, R.F., Cheng, H.H. 2006. Infectious bacterial artificial chromosome clones of Marek's disease virus possessing the complete viral genome derived from Md5 cosmid clones [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 37.
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Methods to Distinquish Selected Serotype 1 Mdv in Dually Infected Chickens
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Dunn, J.R., Gross, S.B., Witter, R.L., Silva, R.F., Lee, L.F. 2006. Methods to distinquish selected serotype 1 MDV in dual-infected chickens [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 39.
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Global Gene Expression Profiling During Cytolytic Infection of Marek's Disease Virus: Array Analysis of Host-Pathogen Interactions
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Heidari, M., Huebner, M., Zhang, H.M., Silva, R.F., Spatz, S.J., Kireev, D. 2006. Global gene expression profiling during cytolytic infection of Marek's disease virus: array analysis of host-pathogen interactions [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 8.
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A Comparison Between Mdv Production in Feather Pulp Versus Feather Follicle Epithelium (Ffe)
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Finlay, J.B., Dunn, J.R., Witter, R.L., Silva, R.F. 2006. A comparison between MDV production in feather pulp versus feather follicle epithelium (FFE)[abstract]. 2006 Merck/Merial National Veterinary Scholar Symposium. Veterinary Medicine and Biomedical Science: Creating the Gumbo of Progress. p. 97.
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Polymorphisms in the Long Repeat Regions of Oncogenic and Attenuated Pathotypes of Marek's Disease Virus 1
- (Peer Reviewed Journal)
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Spatz, S.J., Silva, R.F. 2007. Polymorphisms in the long repeat regions of oncogenic and attenuated pathotypes of Marek's disease virus 1. Virus Genes. 35(1):41-53.
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The Role of the Marek's Disease Virus Ul13 Gene in Generating Cell-Free Virus
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Silva, R.F., Gimeno, I.M. 2006. The role of the Marek's disease virus UL13 gene in generating cell-free virus. American Association of Avian Pathologists and American Veterinary Medical Association Scientific Program. p. 72.
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Mechanisms of Evasion by Herpesviruses
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Silva, R.F. 2006. Mechanisms of evasion by herpesviruses. In: American Association of Avian Pathologists Symposium Program. Impact of Subclinical Immunosuppression on Poultry Production, July 2006, Honolulu, Hawaii. p. 54-60.
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Propagation and Molecular Characterization of a Slow-Growing Subgroup a Avian Leukosis Virus That Was Originally Isolated from Commercial Marek's Disease Vaccines
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Fadly, A.M., Silva, R.F., Taylor, S.P. 2006. Propagation and molecular characterization of a slow-growing subgroup A avian leukosis virus that was originally isolated from commercial Marek's disease vaccines [abstract]. American Veterinary Medical Association and American Association of Avian Pathologists Scientific Program. p. 72.
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Characterization of Various Isolates of a Naturally Occurring Recombinant Avian Leukosis Virus Using Biological Assays and Polymerase Chain Reaction
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Banat, G.R., Silva, R.F., Reed, W.F., Fadly, A.M. 2006. Characterization of various isolates of a naturally occurring recombinant avian leukosis virus using biological assays and polymerase chain reaction [abstract]. American Association of Avian Pathologists and American Veterinary Medical Association Scientific Program. p. 173.
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Skin Leukosis Induced by Mdv
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Heidari, M., Fitzgerald, S.D., Silva, R.F., Zhang, H.M. 2006. Skin leukosis induced by MDV [abstract]. American Association of Avian Pathologists and American Veterinary Medical Association Scientific Program. p. 176.
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Emergence of Subgroup J Avian Leukosis Virus Neutralizing Antibody Escape Variants in Meat-Type Chickens Infected with Virus at Hatch
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Pandiri, A., Reed, W., Silva, R.F., Fadly, A.M. 2006. Emergence of subgroup J avian leukosis virus neutralizing antibody escape variants in meat-type chickens infected with virus at hatch [abstract]. American Association of Avian Pathologists and American Veterinary Medical Association Scientific Program. p. 73.
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Methods to Distinguish Selected Serotype 1 Mdv in Dually Infected Chickens
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Dunn, J.R., Gross, S.B., Witter, R.L., Silva, R.F., Lee, L.F. 2006. Methods to distinguish selected serotype 1 MDV in dually infected chickens [abstract]. American Veterinary Medical Association and American Association of Avian Pathologists Scientific Program. p. 73.
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Isolation and Characterization of An Adventitious Avian Leukosis Virus Isolated from Commercial Marek's Disease Vaccines
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Fadly, A.M., Silva, R.F., Hunt, H.D., Pandiri, A., Davis, C. 2006. Isolation and characterization of an adventitious avian leukosis virus isolated from commercial Marek's disease vaccines. Avian Diseases. 50:380-385.
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Oncogenic Marek's Disease Viruses Lacking the 132 Base Pair Repeats Can Still Be Attenuated by Serial in Vitro Cell Culture Passages
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Silva, R.F., Gimeno, I.M. 2006. Oncogenic Marek's disease viruses lacking the 132 base pair repeats can still be attenuated by serial in vitro cell culture passages. Virus Genes. 34(1):87-90.
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Molecular Characterization of the Marek's Disease Virus Vhs Gene (Ul41)
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Silva, R.F., Gimeno, I.M. 2005. Molecular characterization of the Marek's disease virus vhs gene (UL41)[abstract]. American Veterinary Medical Association. p. 49.
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Gene Deletion Mutants of Marek's Disease Virus, the Next Generation of Recombinant Vaccines?
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Lee, L.F., Silva, R.F., Heidari, M., Reddy, S.M. 2005. Gene deletion mutants of Marek's disease virus: the next generation of recombinant vaccines [abstract]? American Veterinary Medical Association. p. 46.
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Biological Characterization of a Mutant Marek's Disease Virus Lacking the Ul41 Gene (Rmd5dul41)
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Gimeno, I.M., Silva, R.F. 2005. Biological characterization of a mutant Marek's disease virus lacking the UL41 gene (RMD5DUL41)[abstract]. American Veterinary Medical Association. p. 48.
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Novel Criteria for the Diagnosis of Mdv Induced Lymphomas
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Gimeno, I.M., Witter, R.L., Fadly, A.M., Silva, R.F. 2005. Novel criteria for the diagnosis of Marek's disease virus-induced lymphomas. Avian Pathology. 34(4):332-340.
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Deletion of the Marek's Disease Virus (Mdv) Virion Host Shutoff Gene (Ul41): Role of Ul41 in Mdv Pathogenesis
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Silva, R.F., Gimeno, I.M. 2005. Deletion of the Marek's disease virus (MDV) virion host shutoff gene (UL41): role of UL41 in MDV pathogenesis [abstract]. 2nd ESVV Veterinary Herpesvirus Symposium, March 2-4, 2005, Ghent, Belgium. Paper No. 2.18.
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The Pp38 Gene of Marek's Disease Virus (Mdv) Is Necessary for Cytolytic Infection of B Cells and the Maintenance of the Transformed State But Not for Cytolytic ... Spread of Mdv.
- (Peer Reviewed Journal)
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Gimeno, I.M., Witter, R.L., Hunt, H.D., Reddy, S.M., Lee, L.F., Silva, R.F. 2005. The pp38 gene of Marek's disease virus (MDV) is necessary for cytolytic infection of B cells and maintenance of the transformed state but not for cytolytic infection of the feather follicle epithelium and horizontal spread of MDV. Journal of Virology. 79(7):4545-4549.
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Marek's Disease Viruses Lacking the 132 Bp Repeats Are Oncogenic But Can Still Be Attenuated by Serial in Vitro Cell Culture Passages
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Silva, R.F., Gimeno, I.M. 2004. Marek's Disease viruses lacking the 132 bp repeats are oncogenic but can still be attenuated by serial in vitro cell culture passages [abstract]. American Veterinary Medical Association. p. 58.
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Marek's Disease Virus Gene Lorf11 Deletion Mutant Is Essential for Replication in Chickens
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Lee, L.F., Silva, R.F., Cui, X., Reddy, S. 2004. Marek's Disease virus gene LORF11 deletion mutant is essential for replication in chickens [abstract]. American Veterinary Medical Association. p. 60.
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Study of Naturally Occurring Avian Leukosis Virus Infection in a Commercial White Leghorn Breeder Flock
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Mays, J.K., Pandiri, A.R., Silva, R.F., Fadly, A.M. 2004. Study of naturally occurring Avian Leukosis virus infection in a commercial white leghorn breeder flock [abstract]. American Veterinary Medical Association. p. 56.
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Novel Methods to Diagnosis Marek's Disease
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Gimeno, I.M., Witter, R.L., Fadly, A.M., Silva, R.F. 2004. Novel methods to diagnosis Marek's Disease [abstract]. American Veterinary Medical Association. p. 59.
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Oncogenic Mdv's Lacking the 132 Bp Repeats Can Be Attenuated by Repeatedly Passing the Virus in Cell Culture
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Silva, R.F., Gimeno, I.M. 2004. Oncogenic MDVs lacking the 132 bp repeats can be attenuated by repeatedly passing the virus in cell culture [abstract]. International Marek's Disease Symposium Abstracts and Proceedings. Paper No. P.1.
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Isolation of Subgroup a Avian Leukosis Virus from Commercial Marek's Disease Vaccines
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Fadly, A.M., Silva, R.F., Hunt, H.D. 2004. Isolation of subgroup A avian leukosis virus from commercial Marek's disease vaccines [abstract]. International Marek's Disease Symposium Abstracts and Proceedings. Paper No. P.8.
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Characterization of An Open Reading Frame in the Genome of Marek's Disease Virus Common to All Three Serotypes
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Lee, L.F., Silva, R.F., Cui, X., Reddy, S. 2004. Characterization of an open reading frame (LORF11) in the genome of Marek's disease virus common to all three serotypes [abstract]. International Marek's Disease Symposium Abstracts and Proceedings. Paper No. I. 5.
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Marek's Disease Virus Encoded Meq Gene Is Involved in Transformation of Lymphocytes But Dispensable for Replication
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Lupiani, B.M., Lee, L.F., Cui, X., Gimeno, I.M., Anderson, A., Morgan, R.W., Silva, R.F., Witter, R.L., Kung, H., Reddy, S. 2004. Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication. Proceedings of the National Academy of Sciences. 101(32):11815-11820.
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Expansion of a Unique Region in the Marek's Disease Virus Genome Occurs Concomitantly with Attenuation But Is Not Sufficient to Cause Attenuation
- (Peer Reviewed Journal)
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Silva, R.F., Reddy, S., Lupiani, B. 2004. Expansion of a unique region in the Marek's disease virus genome occurs concomitantly with attenuation but is not sufficient to cause attenuation. Journal of Virology. 78(2):733-740.
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Detection of Exogenous and Endogenous Avian Leukosis Viruses in Commercial Marek's Disease Vaccines
- (Proceedings/Symposium)
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Fadly, A.M., Silva, R.F., Hunt, H.D. 2003. Detection of exogenous and endogenous avian leukosis viruses in commercial marek's disease vaccines. In: Proceedings of the 170th Annual Meeting of the United States Animal Health Association, October 9-16, 2003, San Diego, California. p. 524-525.
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Comparison of Chinese Field Strains of Avian Leukosis Subgroup J Viruses with Prototype Strain Hprs-103 and U.S. Strains
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Cui, Z., Du, Y., Zhang, Z., Silva, R.F. 2003. Comparison of chinese field strains of avian leukosis subgroup J viruses with prototype strain HPRS-103 and U.S. strains. Avian Diseases. 47:1321-1330.
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New Techniques for Diagnosis of Marek's Disease in Chickens
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Shaw, G., Gimeno, I.M., Witter, R.L., Lee, L.F., Silva, R.F., Fadly, A.M. 2003. New techniques for diagnosis of Marek's disease in chickens. Annual Merck Merial Veterinary Scholars Symposium. p. 105.
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Characterization of the Marek's Disease Virus Lorf-10 Gene
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Silva, R.F., Lupiani, B.M., Reddy, S. 2003. Characterization of the marek's disease virus LORF-10 gene. World Veterinary Poultry Association Congress Proceedings. p. 101.
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Identification and Characterization of Lorf11, a Gene Unique to the Three Serotypes of Marek's Disease Virus
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Lee, L.F., Cui, X., Reddy, S., Silva, R.F. 2003. Identification and characterization of lorf11, a gene unique to the three serotypes of marek's disease virus. World Veterinary Poultry Association Congress Proceedings. p. 145.
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Pathogenicity of a Molecular Clone of a Field Strain of Subgroup J Avian Leukosis Virus
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Lupiani, B.M., Pandiri, A.R., Mays, J.K., Conklin, K.F., Silva, R.F., Reed, W.M., Fadly, A.M. 2003. Pathogenicity of a molecular clone of a field strain of subgroup J avian leukosis virus [abstract]. American Veterinary Medical Association. p. 100.
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Role of the Gene Pp38 in the Pathogenesis of Marek's Disease Virus
- (Proceedings/Symposium)
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Gimeno, I.M., Hunt, H.D., Witter, R.L., Neumann, U., Reddy, S., Silva, R.F. 2003. Role of the gene pp38 in the pathogenesis of marek's disease virus. World Veterinary Poultry Association Congress Proceedings. p. 101.
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The Effect of Deleting Or Inverting the 132 Bp Repeats in a Pathogenic Mdv
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Silva, R.F., Reddy, S., Lupiani, B. 2003. The effect of deleting or inverting the 132 bp repeats in a pathogenic mdv [CD-ROM]. Workshop on Molecular Pathogenesis of Marek's Disease and Avian Immunology. Limassol, Cyprus, BARD.
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Pathogenicity of Two Recombinant Avian Leukosis Viruses
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Lupiani, B., Williams, S.M., Silva, R.F., Hunt, H.D., Fadly, A.M. 2003. Pathogenicity of two recombinant avian leukosis viruses. Avian Diseases. 47:425-432.
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The Effect of Deleting Or Inverting the 132 Base Pair Repeats in a Pathogenic Mdv
- (Abstract)
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Silva, R.F., Lupiani, B., Reddy, S.M. 2002. The effect of deleting or inverting the 132 base pair repeats in a pathogenic mdv [abstract]. Workshop on Molecular Pathogenesis of Marek's Disease and Avian Immunology. p. 49.
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Role of 1.8 Kb Mrna Family of Transcripts in Marek's Disease Virus Pathogenesis
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Silva, R.F., Lupiani, B., Reddy, S.M. 2002. Role of 1.8 kb mrna family of transcripts in marek's disease virus pathogenesis [abstract]. American Veterinary Medical Association. p. 18.
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Recombinant Vaccines and DNA Vaccines-Unfulfilled Promises
- (Proceedings/Symposium)
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Silva, R.F. 2002. Recombinant vaccines and DNA vaccines--unfulfilled promises. American Association of Avian Pathologists. p. 32-45.
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