Title: Effect of High Levels of Ionizing Radiation on Animal Tissues (Formation of Different Carbonyls and Force Feeding of these to Rats)

Authors: Monty, K.J.; Gambal, D.

Publishers: The John Hopkins University, Baltimore, Maryland

Year: 1956

Sponsors: DA-49-007-MD-631

Subjects: Radiation chemistry, and wholesomeness of meats and carbonyls.

Comments: (Authors) Summary: In our previous report, we described methods for the extraction and quantitative estimation of "fat-soluble" and "water-soluble" carbonyl compounds in animal tissues. The methods depend upon the spectrophotometric examination of 2, 4-dinitrophenyl hydrazones prepared from benzene and aqueous trichloroacetic acid extracts of tissue samples. The absorption maxima and specific absorbancies of the crystalline dinitrophenyl hydrazones of a number of aliphatic and aromatic aldehydes and ketones were presented. The present report will deal with the application of these methods to the study of the formation of carbonyl compounds in beef liver, muscle, and kidney by high doses of ionizing radiation, and will consider our approach to the qualitative identification of these carbonyl compounds.